CN105722979A - 肝癌相关的基因特异性siRNA、包含所述siRNA的双链寡RNA分子和包含它们的用于预防或治疗癌症的组合物 - Google Patents

肝癌相关的基因特异性siRNA、包含所述siRNA的双链寡RNA分子和包含它们的用于预防或治疗癌症的组合物 Download PDF

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Publication number
CN105722979A
CN105722979A CN201480049435.3A CN201480049435A CN105722979A CN 105722979 A CN105722979 A CN 105722979A CN 201480049435 A CN201480049435 A CN 201480049435A CN 105722979 A CN105722979 A CN 105722979A
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sirna
double
strand
cancer
rna molecule
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Pending
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CN201480049435.3A
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Chinese (zh)
Inventor
蔡济旭
尹坪伍
金翰娜
朴翰浯
韩宝兰
高映浩
磪基恩
金宰恩
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Bioneer Corp
Sanofi Aventis Korea Co Ltd
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Bioneer Corp
Sanofi Aventis Korea Co Ltd
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CN201480049435.3A 2013-07-09 2014-07-09 肝癌相关的基因特异性siRNA、包含所述siRNA的双链寡RNA分子和包含它们的用于预防或治疗癌症的组合物 Pending CN105722979A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2013-0080580 2013-07-09
KR1020130080580A KR20150006743A (ko) 2013-07-09 2013-07-09 간암 연관 유전자 특이적 siRNA, 그러한 siRNA를 포함하는 이중나선 올리고 RNA 구조체 및 이를 포함하는 암 예방 또는 치료용 조성물
PCT/KR2014/006146 WO2015005670A1 (en) 2013-07-09 2014-07-09 LIVER CANCER RELATED GENES-SPECIFIC siRNA, DOUBLE-STRANDED OLIGO RNA MOLECULES COMPRISING THE siRNA, AND COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING THE SAME

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CN105722979A true CN105722979A (zh) 2016-06-29

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CN201480049435.3A Pending CN105722979A (zh) 2013-07-09 2014-07-09 肝癌相关的基因特异性siRNA、包含所述siRNA的双链寡RNA分子和包含它们的用于预防或治疗癌症的组合物

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US (1) US20160145624A1 (enExample)
EP (1) EP3019612A4 (enExample)
JP (1) JP2016523557A (enExample)
KR (1) KR20150006743A (enExample)
CN (1) CN105722979A (enExample)
WO (1) WO2015005670A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111132682A (zh) * 2017-07-28 2020-05-08 雷莫内克斯生物制药有限公司 用于预防或治疗肝癌的药物组合物
CN113271980A (zh) * 2018-11-28 2021-08-17 柏业公司 包含雄激素受体特异性序列的双链寡核苷酸构建体以及包含其的用于预防脱发和促进头发生长的组合物
CN113308541A (zh) * 2021-03-29 2021-08-27 广州医科大学 c-Myc和Chd1l在肿瘤治疗和诊断中的应用
CN115282283A (zh) * 2022-06-21 2022-11-04 浙江浥眸生物科技有限公司 一种小分子药物-寡核苷酸偶联物及其应用

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KR101861738B1 (ko) 2016-08-24 2018-05-29 (주)바이오니아 마이크로 rna를 포함하는 이중나선 올리고 rna 구조체
EP3917540A1 (en) 2019-01-31 2021-12-08 Ionis Pharmaceuticals, Inc. Modulators of yap1 expression
KR20210120581A (ko) 2020-03-27 2021-10-07 연세대학교 산학협력단 저산소성 대장암의 예방 또는 치료용 조성물
WO2025024334A1 (en) 2023-07-21 2025-01-30 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods

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EP1560931B1 (en) * 2002-11-14 2011-07-27 Dharmacon, Inc. Functional and hyperfunctional sirna
WO2007044468A2 (en) * 2005-10-05 2007-04-19 The Cbr Institute For Biomedical Research, Inc. Method to treat flavivirus infection with sirna
JP2008295327A (ja) * 2007-05-30 2008-12-11 Fujifilm Corp 口腔扁平上皮癌の検出方法、及び抑制方法
KR101224828B1 (ko) * 2009-05-14 2013-01-22 (주)바이오니아 siRNA 접합체 및 그 제조방법
WO2011000106A1 (en) * 2009-07-01 2011-01-06 Protiva Biotherapeutics, Inc. Improved cationic lipids and methods for the delivery of therapeutic agents
US8871509B2 (en) * 2009-11-06 2014-10-28 Chung-Ang University-Academy Corporation Foundation Nanoparticle-based gene delivery systems
PL2736887T3 (pl) * 2011-07-29 2018-03-30 Karyopharm Therapeutics, Inc. Modulatory transportu jądrowego zawierające ugrupowanie hydrazydu i ich zastosowania

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111132682A (zh) * 2017-07-28 2020-05-08 雷莫内克斯生物制药有限公司 用于预防或治疗肝癌的药物组合物
CN111132682B (zh) * 2017-07-28 2024-04-26 雷莫内克斯生物制药有限公司 用于预防或治疗肝癌的药物组合物
US12076336B2 (en) 2017-07-28 2024-09-03 Lemonex Inc. Pharmaceutical composition for preventing or treating liver cancer
CN113271980A (zh) * 2018-11-28 2021-08-17 柏业公司 包含雄激素受体特异性序列的双链寡核苷酸构建体以及包含其的用于预防脱发和促进头发生长的组合物
CN113271980B (zh) * 2018-11-28 2024-02-02 柏业公司 包含雄激素受体特异性序列的双链寡核苷酸构建体以及包含其的用于预防脱发和促进头发生长的组合物
CN113308541A (zh) * 2021-03-29 2021-08-27 广州医科大学 c-Myc和Chd1l在肿瘤治疗和诊断中的应用
CN115282283A (zh) * 2022-06-21 2022-11-04 浙江浥眸生物科技有限公司 一种小分子药物-寡核苷酸偶联物及其应用

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Publication number Publication date
EP3019612A1 (en) 2016-05-18
WO2015005670A1 (en) 2015-01-15
KR20150006743A (ko) 2015-01-19
EP3019612A4 (en) 2017-06-28
JP2016523557A (ja) 2016-08-12
US20160145624A1 (en) 2016-05-26

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