KR20150006743A - 간암 연관 유전자 특이적 siRNA, 그러한 siRNA를 포함하는 이중나선 올리고 RNA 구조체 및 이를 포함하는 암 예방 또는 치료용 조성물 - Google Patents

간암 연관 유전자 특이적 siRNA, 그러한 siRNA를 포함하는 이중나선 올리고 RNA 구조체 및 이를 포함하는 암 예방 또는 치료용 조성물 Download PDF

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KR20150006743A
KR20150006743A KR1020130080580A KR20130080580A KR20150006743A KR 20150006743 A KR20150006743 A KR 20150006743A KR 1020130080580 A KR1020130080580 A KR 1020130080580A KR 20130080580 A KR20130080580 A KR 20130080580A KR 20150006743 A KR20150006743 A KR 20150006743A
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rna
zbtb7a
yap1
chd1l
artificial sequence
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Korean (ko)
Inventor
채제욱
윤평오
김한나
박한오
한보람
고영호
최기은
김재은
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(주)바이오니아
주식회사 사노피-아벤티스 코리아
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Priority to KR1020130080580A priority Critical patent/KR20150006743A/ko
Priority to JP2016525280A priority patent/JP2016523557A/ja
Priority to EP14823194.7A priority patent/EP3019612A4/en
Priority to US14/903,043 priority patent/US20160145624A1/en
Priority to PCT/KR2014/006146 priority patent/WO2015005670A1/en
Priority to CN201480049435.3A priority patent/CN105722979A/zh
Publication of KR20150006743A publication Critical patent/KR20150006743A/ko
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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KR1020130080580A 2013-07-09 2013-07-09 간암 연관 유전자 특이적 siRNA, 그러한 siRNA를 포함하는 이중나선 올리고 RNA 구조체 및 이를 포함하는 암 예방 또는 치료용 조성물 Withdrawn KR20150006743A (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
KR1020130080580A KR20150006743A (ko) 2013-07-09 2013-07-09 간암 연관 유전자 특이적 siRNA, 그러한 siRNA를 포함하는 이중나선 올리고 RNA 구조체 및 이를 포함하는 암 예방 또는 치료용 조성물
JP2016525280A JP2016523557A (ja) 2013-07-09 2014-07-09 肝臓癌関連遺伝子特異的ｓｉＲＮＡ、そのようなｓｉＲＮＡを含む二重らせんオリゴＲＮＡ構造体及びこれを含む癌予防または治療用組成物
EP14823194.7A EP3019612A4 (en) 2013-07-09 2014-07-09 LIVER CANCER RELATED GENES-SPECIFIC siRNA, DOUBLE-STRANDED OLIGO RNA MOLECULES COMPRISING THE siRNA, AND COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING THE SAME
US14/903,043 US20160145624A1 (en) 2013-07-09 2014-07-09 LIVER CANCER RELATED GENES-SPECIFIC siRNA, DOUBLE-STRANDED OLIGO RNA MOLECULES COMPRISING THE siRNA, AND COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING THE SAME
PCT/KR2014/006146 WO2015005670A1 (en) 2013-07-09 2014-07-09 LIVER CANCER RELATED GENES-SPECIFIC siRNA, DOUBLE-STRANDED OLIGO RNA MOLECULES COMPRISING THE siRNA, AND COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING THE SAME
CN201480049435.3A CN105722979A (zh) 2013-07-09 2014-07-09 肝癌相关的基因特异性siRNA、包含所述siRNA的双链寡RNA分子和包含它们的用于预防或治疗癌症的组合物

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Application Number Priority Date Filing Date Title
KR1020130080580A KR20150006743A (ko) 2013-07-09 2013-07-09 간암 연관 유전자 특이적 siRNA, 그러한 siRNA를 포함하는 이중나선 올리고 RNA 구조체 및 이를 포함하는 암 예방 또는 치료용 조성물

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KR20150006743A true KR20150006743A (ko) 2015-01-19

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KR1020130080580A Withdrawn KR20150006743A (ko) 2013-07-09 2013-07-09 간암 연관 유전자 특이적 siRNA, 그러한 siRNA를 포함하는 이중나선 올리고 RNA 구조체 및 이를 포함하는 암 예방 또는 치료용 조성물

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US (1) US20160145624A1 (enExample)
EP (1) EP3019612A4 (enExample)
JP (1) JP2016523557A (enExample)
KR (1) KR20150006743A (enExample)
CN (1) CN105722979A (enExample)
WO (1) WO2015005670A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020111614A1 (ko) * 2018-11-28 2020-06-04 (주)바이오니아 안드로젠 수용체 특이적 서열을 포함하는 이중나선 올리고뉴클레오티드 구조체, 및 이를 포함하는 탈모 예방 및 발모용 조성물
KR20210120581A (ko) 2020-03-27 2021-10-07 연세대학교 산학협력단 저산소성 대장암의 예방 또는 치료용 조성물

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101861738B1 (ko) 2016-08-24 2018-05-29 (주)바이오니아 마이크로 rna를 포함하는 이중나선 올리고 rna 구조체
CN116898870A (zh) * 2017-07-28 2023-10-20 雷莫内克斯生物制药有限公司 用于预防或治疗肝癌的药物组合物
WO2020160453A1 (en) 2019-01-31 2020-08-06 Ionis Pharmaceuticals, Inc. Modulators of yap1 expression
CN113308541A (zh) * 2021-03-29 2021-08-27 广州医科大学 c-Myc和Chd1l在肿瘤治疗和诊断中的应用
CN115282283B (zh) * 2022-06-21 2024-11-29 上海交通大学 一种小分子药物-寡核苷酸偶联物及其应用
WO2025024334A1 (en) 2023-07-21 2025-01-30 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods

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EP2213738B1 (en) * 2002-11-14 2012-10-10 Dharmacon, Inc. siRNA molecules targeting Bcl-2
WO2007044468A2 (en) * 2005-10-05 2007-04-19 The Cbr Institute For Biomedical Research, Inc. Method to treat flavivirus infection with sirna
JP2008295327A (ja) * 2007-05-30 2008-12-11 Fujifilm Corp 口腔扁平上皮癌の検出方法、及び抑制方法
KR101224828B1 (ko) * 2009-05-14 2013-01-22 (주)바이오니아 ｓｉＲＮＡ 접합체 및 그 제조방법
US8569256B2 (en) * 2009-07-01 2013-10-29 Protiva Biotherapeutics, Inc. Cationic lipids and methods for the delivery of therapeutic agents
EP2496268A4 (en) * 2009-11-06 2013-06-19 Univ Chung Ang Ind GENERATING SYSTEMS ON NANOPARTICLE BASIS
PL3333164T3 (pl) * 2011-07-29 2023-12-18 Karyopharm Therapeutics Inc. Modulatory transportu jądrowego zawierające ugrupowanie hydrazydu i ich zastosowania

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020111614A1 (ko) * 2018-11-28 2020-06-04 (주)바이오니아 안드로젠 수용체 특이적 서열을 포함하는 이중나선 올리고뉴클레오티드 구조체, 및 이를 포함하는 탈모 예방 및 발모용 조성물
KR20210120581A (ko) 2020-03-27 2021-10-07 연세대학교 산학협력단 저산소성 대장암의 예방 또는 치료용 조성물

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US20160145624A1 (en) 2016-05-26
JP2016523557A (ja) 2016-08-12
CN105722979A (zh) 2016-06-29
WO2015005670A1 (en) 2015-01-15
EP3019612A4 (en) 2017-06-28
EP3019612A1 (en) 2016-05-18

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