CN1056998C - A Chinese medicinal pill for treating bone tuberculosis and its preparation method - Google Patents
A Chinese medicinal pill for treating bone tuberculosis and its preparation method Download PDFInfo
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- CN1056998C CN1056998C CN97115213A CN97115213A CN1056998C CN 1056998 C CN1056998 C CN 1056998C CN 97115213 A CN97115213 A CN 97115213A CN 97115213 A CN97115213 A CN 97115213A CN 1056998 C CN1056998 C CN 1056998C
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a pill for treating bone tuberculosis and a preparation method thereof, wherein the pill comprises the following raw material medicaments: 29-30 g of honeysuckle, 30 g of bletilla striata, 30-40 g of ephedra, 20-30 g of fructus amomi, 20-30 g of angelica sinensis, 30 g of malt, 2-30 g of medicinal fermented mass, 30 g of hawthorn, 10 g of deerhorn glue, 25-30 g of dragon bone, 100 g of prepared rhizome of rehmannia, 10 g of ginseng, 1 g of pearl, 10 g of cinnamon, 20 g of morinda officinalis, 25-30 g of raw Chinese yam, 15 g of radix stemonae, 5 g of centipede, 20 g of liquorice, 30 g of semen brassicae, 0.5 g/tablet of leemide, p-aminosalicylate or/and 80-100 tablets of rifampicin. Clinical data show that the bone tuberculosis pill has the cure rate of 86.7 percent for the bone tuberculosis, the effective rate of 99.06 percent, no toxic or side effect, no drug resistance and no relapse after healing, and has remarkable effect on male and female patients of different ages and bone tuberculosis patients of different types.
Description
The present invention relates to a kind of bone tuberculosis pill and preparation method thereof of specially controlling.
Western medicine bone tuberculosis informal dress is taken toxic side effect for a long time with isoniazid, to tablets such as amido sodium salicylate, rifampicin, can develop immunity to drugs more easily recurrence of back.
The objective of the invention is to develop kind to bone tuberculosis cure rate height, have no side effect and Drug resistance, the bone tuberculosis ball and the method for making thereof that do not recur after more.
The material medicine of bone tuberculosis ball of the present invention is as follows:
Flos Lonicerae 29-30 gram, the Pseudobulbus Bletillae (Rhizoma Bletillae) 30 grams, Herba Ephedrae 30-40 gram, Fructus Amomi 20-30 gram, Radix Angelicae Sinensis 20-30 gram, Fructus Hordei Germinatus 30 grams, Massa Medicata Fermentata 2-30 gram, Fructus Crataegi 30 grams, Colla cornus cervi 10 grams, Os Draconis 25-30 gram, Radix Rehmanniae Preparata 100 grams, Radix Ginseng 10 grams, Margarita 1 gram, Cortex Cinnamomi 10 grams, Radix Morindae Officinalis 20 grams, Rhizoma Dioscoreae 25-30 gram, the Radix Stemonae 15 grams, Scolopendra 5 gram, Radix Glycyrrhizae 20 grams, the isoniazid of Semen Sinapis Albae 30 grams, 0.5 gram/sheet, to the amido sodium salicylate or/and rifampicin 80-100 sheet.
In above-mentioned prescription, can also add Rhizoma Zingiberis Preparatum 10-15 gram, Magnetitum 10-15 gram, Fructus Forsythiae 15-20 gram.
The preparation method of bone tuberculosis pill of the present invention is as follows:
1. medical material standard: Semen Sinapis Albae is pure white Semen Sinapis forbidding Semen Sinapis, Radix Ginseng red in vain all can, Margarita is Margaritas such as 1-2, Herba Ephedrae wants the green heart of color red, Fructus Amomi will be removed the peel, Os Draconis will remove clean earth, Radix Rehmanniae Preparata is wanted nine steamings, nine solarizations;
2. all batching will be picked up clean silt particle, foreign material and be crossed scalping once, Os Draconis water logging two days, and the boiled water flushing, the Margarita clear water is cleaned the back and was steamed 20 minutes with bean curd, and Radix Ginseng removes clean reed head;
3. medicated powder processing: all components are divided into two groups of pulverizing, and one group is generally Chinese medicine, and one group is Margarita and Os Draconis etc., first coarse pulverization, after be finely ground to powder, stir disinfection by ultraviolet light 30 minutes;
4. with the Mel heating and filtering, decoct, remove the wax end, endure to dropping liquid Cheng Zhu with the copper pot;
5. above-mentioned medicated powder and Mel are stirred and make pill, seal with wax after packing with sterile paper of ultraviolet and wax shell.
The clinical treatment situation is as follows:
Physical data:
1. sex: male's 49 examples, women's 57 examples.
2. age: 8 examples of person below 10 years old, 11-20 year person's 18 examples, 21-30 year person's 27 examples, 31-40 year person's 3 examples, 41-50 year person's 11 examples, 51-60 year person's 3 examples, person's 2 examples more than 60 years old.
3. the course of disease: 11 examples below a year, 1-5 70 examples, 6-10 20 examples, 11-15 4 examples, 1 example more than 20 years.
4. site of pathological change: cervical vertebra 1 example, thoracic vertebra 26 examples, lumbar vertebra 39 examples, sacro-iliac joints 5 examples, hip joint 11 examples, knee joint 5 examples, ankle joint 5 examples, femur 1 example, tibia 1 example, foot 6 examples, shoulder joint 1 example, elbow joint 1 example, carpal joint 1 example, hand 3 examples.
5. this is organized among the 106 routine patients, and routed person's 33 examples of cold abscess are arranged, chronic sinus tract former's 32 examples, and paraplegia person's 7 examples merge pulmonary tuberculosis person's 11 examples, merge lymphoid tuberculosis person's 2 examples.
Instructions of taking: from 6 o'clock mornings, per 6 hours clothes 1 balls, children's is cut down according to the circumstance, warm boiled water.Period in a medicine is avoided clothes rareripe, living Bulbus Allii, donkey oil, Folium Allii tuberosi etc.
The treatment standard:
(1) clinical cure: General Symptoms disappears, and appetite is promoted, weight increase.Local symptom disappears, swollen disappearing, and pain is ended.Function of joint takes a turn for the better, the healing of crevasse sinus tract.The chemical examination erythrocyte sedimentation rate is normal, and the X line is taken the photograph the visible sick bone reparation of sheet, and bone density increases, and sequestrum absorbs, the edge Chu, neat that disappears.Follow up a case by regular visits to not recurrence over one year, can participate in general physical work.
(2) produce effects: whole body and local symptom are obviously improved, and appetite increases, spiritual amelioration, and abscess is dwindled, and sinus tract heals substantially.The chemical examination erythrocyte sedimentation rate is normal, and the X line is taken the photograph sheet prompting sclerotin and repaired substantially, can participate in light physical labor.
(3) effective: body constitution is recovered to some extent, and local symptom is improved, and X line prompting sclerotin is repaired to some extent.
(4) invalid: through treatment in a year, clinical symptoms did not have improvement, and the X line is taken the photograph sheet strength of character matter and destroyed obviously change of nothing.
Therapeutic outcome:
This is organized among the 106 routine patients, cures 92 examples, accounts for 86.7%, and produce effects 11 examples account for 10.37%, and effective 2 examples account for 1.99%, invalid 1 example, and total effective rate reaches 99.06%, cures in 92 examples that no case was recurrence through check.
The sick curative effect statistics of 106 routine tuberculosis of bone and joint
| Cure | Produce effects | Effectively | Invalid | Add up to |
| 92 86.7％ | 11 10.37％ | 2 1.99％ | 1 0.94％ | 106 100％ |
Cold abscess person's 33 examples occur, cure 32 examples; Chronic sinus tract former's 32 examples are cured 30 examples, form paraplegia person's 7 examples, cure 6 examples, and 1 routine produce effects merges pulmonary tuberculosis person's 11 examples, cures 11 examples, merges lymphoid tuberculosis person's 2 examples, cures 2 examples.
The course of treatment: in this group case, 3 months with interior healing person's 18 examples, 4-7 month healing person 68 examples, 8-11 month healing person 20 examples, healing person's 4 examples more than a year.
Typical case's medical record
Medical record one:
Open * *, the woman, 16 years old, then ditch people from village ground in Liu Jiahui township, Lin County, Shanxi.The patient begins to feel that in February, 84 cervical region aches because of catching cold, the whole body is weak, spontaneous perspiration, aversion to cold and cold limbs.Local doctor is by the rheumatism treatment, and characteristic of disease increases the weight of gradually, numb limbs and tense tendons, the time Fa Shixiu as getting an electric shock, gradually lose one's senses to extremity, wither soft need not, the cervical pain unable to move around, lack of appetite is indigestion and loss of appetite.84 year August 22, sheet was taken the photograph by the People's Hospital, Nikkei Luliang Prefecture, was diagnosed as neck 4,5,6 tuberculosis of spine.On August 24th, 1984 was admitted to hospital.Symptom is: show light desert, and a little less than the respiratory gas, emaciated physique, quadriplegia, spiritlessness and weakness, lusterless complexion, skin is dull and heavy, pale tongue, a little less than the tongue body fistula, no fur.Experience: malnutrition, cardiopulmonary are normal, the abdominal part softness, the liver spleen does not touch, blood pressure 90/60mmHg, 37.5 ℃ of body temperature.The anti-consumptive disease Western medicine of during clothes bone tuberculosis ball, stopping using, through bimestrial treatment, diet increases, and upper extremity function recovers gradually, can under helping, others sit up, and can own end bowl, have a meal with soupspoon.Behind three first quarter moons, lower limb function and consciousness are also recovered gradually, can hold up the bed walking down.Can walk according to cane after four months.On January 10th, 1985 left hospital, the bone tuberculosis pill for curing of going home to continue to take, and check on August 6th, 1985, complexion is normal, weight increase, this limb function is recovered fully, and 20 li hill paths of walking do not have tired sense.The X line is taken the photograph sheet and seen: precentrum destruction region bone density all has and increases, and edge clear is improper with regard to the line of force, and vertebral body becomes wedge to change, and fully recovers through check.
Medical record two:
Cao * *, woman, 31 years old, area just outside a city gate town, Yangcheng County, Shanxi Li Jie people from village.Right chi radius portion takes place May 11 nineteen eighty-three and swells and ache in the patient, left side ancon dull pain, and aggravation gradually is diagnosed as right side chi radius tuberculous osteomyelitis through the mountain doctor Second Academy.Economizing public security hospital hospitalization March, mouthful fertile, intramuscular injection, quiet antituberculosis drugs thing, the state of an illness commentariess on classics of not getting better, the prescription on individual diagnosis of coming.The conscious hectic fever night sweat of patient, heavy towards light dusk, soreness of waist sleepiness, lack of appetite is indigestion and loss of appetite, and left ancon pain can not be rotated and be bent and stretched, and there is pus second month in a season the part.Symptom is: emaciated physique, and lusterless complexion, two cheekbones are little red, and spirit is rotten depressed, is unable to leave the bed, and it is fat swollen that right wrist to elbow is the spindle shape, and capitulum ulnae has sinus tract one place, on every side the purple dark pastiness of color of the leather.The big lymphatic abscess of the 4 * 5Cm of portion, not crevasse are arranged at right jaw bottom.Left side ancon forms the big abscess of 10 * 14Cm.Right groin has the abscess of 10 * 8Cm, not crevasse, the lips and tongue being pale, few tongue.Palpation: deep,thready and forceless pulse and counting, axillary lymph knot enlargement and hard.Withdraw anti-consumptive disease Western medicine during the treatment, mainly with the bone tuberculosis pill for curing.After 20 days, diet increases, left ancon pain relief, but out-of-bed activity, and crevasse healing after 50 days, hectic fever moves back after 80 days, and night sweat ends, and left ancon swelling disappears, and pain is ended, 11 kilograms of weight increase.Check in JIUYUE, 1985 film making: the key sclerotin increase in density of radius and ulna, neat in edge has several garden shape lucent areas, and General Symptoms disappears, the crevasse healing, antisecosis, disease is fully recovered.
To sum up state institute, bone tuberculosis ball of the present invention has special effect to bone tuberculosis:
1. cure rate is up to 86.7%, total effective rate 99.06%.
2. have no side effect, without the resistance to the action of a drug, do not recur after healing.
3. for the men and women's of all ages and classes patient and dissimilar bone tuberculosis special effect is arranged all.
Claims (3)
1. pill for the treatment of bone tuberculosis is characterized in that material medicine is as follows:
Flos Lonicerae 29-30 gram, the Pseudobulbus Bletillae (Rhizoma Bletillae) 30 grams, Herba Ephedrae 30-40 gram, Fructus Amomi 20-30 gram, Radix Angelicae Sinensis 20-30 gram, Fructus Hordei Germinatus 30 grams, Massa Medicata Fermentata 2-30 gram, Fructus Crataegi 30 grams, Colla cornus cervi 10 grams, Os Draconis 25-30 gram, Radix Rehmanniae Preparata 100 grams, Radix Ginseng 10 grams, Margarita 1 gram, Cortex Cinnamomi 10 grams, Radix Morindae Officinalis 20 grams, Rhizoma Dioscoreae 25-30 gram, the Radix Stemonae 15 grams, Scolopendra 5 gram, Radix Glycyrrhizae 20 grams, the isoniazid of Semen Sinapis Albae 30 grams, 0.5 gram/sheet, to the amido sodium salicylate or/and rifampicin 80-100 sheet.
2. bone tuberculosis pill as claimed in claim 1 is characterized in that having increased following material medicine:
Rhizoma Zingiberis Preparatum 10-15 gram Magnetitum 10-15 gram Fructus Forsythiae 15-20 gram
3. a kind of method for making of the pill of treatment bone tuberculosis as claimed in claim 1 or 2, its feature is as follows:
(1) medical material standard: Semen Sinapis Albae is a pure white Semen Sinapis forbidding Semen Sinapis, Radix Ginseng red in vain all can, Margarita is Margaritas such as 1-2, Herba Ephedrae wants the green heart of color red, Fructus Amomi will be removed the peel, Os Draconis will remove clean earth, Radix Rehmanniae Preparata is wanted nine steamings, nine solarizations;
(2) all batching will be picked up clean silt particle, foreign material and be crossed scalping once, Os Draconis water logging two days, and the boiled water flushing, the Margarita clear water is cleaned the back and was steamed 20 minutes with bean curd, and Radix Ginseng removes clean reed head;
(3) medicated powder processing: all components are divided into two groups of pulverizing, and one group is general Chinese medicine, and one group is Margarita and Os Draconis etc., first coarse pulverization, after be finely ground to powder, stir, disinfection by ultraviolet light 30 minutes, standby;
(4) with the Mel heating and filtering, decoct with the copper pot, remove the wax end, endure to dropping liquid Cheng Zhu;
(5) above-mentioned medicated powder and Mel are stirred make pill, disappeared with ultraviolet and seal with wax after malicious paper and wax shell are packed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97115213A CN1056998C (en) | 1997-08-19 | 1997-08-19 | A Chinese medicinal pill for treating bone tuberculosis and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN97115213A CN1056998C (en) | 1997-08-19 | 1997-08-19 | A Chinese medicinal pill for treating bone tuberculosis and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1208625A CN1208625A (en) | 1999-02-24 |
| CN1056998C true CN1056998C (en) | 2000-10-04 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97115213A Expired - Fee Related CN1056998C (en) | 1997-08-19 | 1997-08-19 | A Chinese medicinal pill for treating bone tuberculosis and its preparation method |
Country Status (1)
| Country | Link |
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| CN (1) | CN1056998C (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1095600A (en) * | 1992-11-26 | 1994-11-30 | 王璐林 | Bone regeneration pill |
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1997
- 1997-08-19 CN CN97115213A patent/CN1056998C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1095600A (en) * | 1992-11-26 | 1994-11-30 | 王璐林 | Bone regeneration pill |
Non-Patent Citations (3)
| Title |
|---|
| 《中成药研究》(4) 1988.4.30 曹殿明等，骨疸胶囊治疗 * |
| 《湖南中医杂志》3(6) 1987.6.30 周书望，骨痨丸治疗骨，关节结核-附215例临床观察 * |
| 《湖南中医杂志》3(6) 1987.6.30 周书望，骨痨丸治疗骨，关节结核-附215例临床观察;《中成药研究》(4) 1988.4.30 曹殿明等，骨疸胶囊治疗 * |
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