CN105688171A - Chicken feed additive and preparation method thereof - Google Patents

Abstract

The invention discloses a chicken feed additive and a preparation method thereof. The feed additive comprises the following medicinal materials of pinellia ternate, tuckahoe, ginger, Chinese honey locust, perillaseed, orange peel, mangnolia officinalis, semen brassicae, platycodon grandiflorum, concentrated beef extract, seed of Chinese waxgourd, perilla leaf, Chinese tamarisk twig, apricot kernel, inula flower, cynanchum glaucescens, common adenostema herb, eucalyptus tereticornis, centipeda minima, wutaishan mushroom, watermelon peel, fineleaf schizonepeta herb, sium latifolium, Chinese parsnip root and licorice root. The feed additive has the beneficial effects that the treatment effects of expelling phlegm, stopping cough and relieving asthma, and relieving exterior syndrome and expelling cold are realized; when the wind and cold type cough syndrome of chicken is treated, the treatment effect is obvious, the side effect is low, the curative rate is high, the treatment cycle is short, the easiness in reoccurrence is avoided, and the like.

Description

A kind of young additive agent for chicken feed and preparation method thereof

This case is divisional application, and the denomination of invention of original application is: for medicine treating chicken wind-cold type cough and preparation method thereof, the applying date of original application is: 2014-03-20, and the application number of original application is: 201410103548.9。

Technical field

The present invention relates to field of feed additive technology, particularly to a kind of young additive agent for chicken feed and preparation method thereof。

Background technology

Chicken is normally breathing per minute 20～40 times, and frequency of respiration is accelerated to be exactly breathe heavily。Have with mouth breathing and stridulate。Chicken breathes heavily and is easiest to recognize when chicken group peace and quiet in night。High temperature, stifling etc. stress make chicken accelerated breathing, and one or more diseases can make chicken breathe heavily and have other respiratory symptoms, and what have is called " respiratory complication (is levied) " or directly claims " respiratory symptom of chicken ", " respiratory tract disease "。

The existing antibacterial of chicken cough cause of disease, also has virus, some appearance mixed infection。Traditional Chinese veterinary medicine thinks the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens, the criminal's of accumulateing lung in pathogenic factor, and sputum blocks trachea, causes cough and asthma, then evil passes edema caused by disorder of QI, checks lung machine, so that clear respectful mistake department, the heap soil or fertilizer over and around the roots of QI rising in reverse order expectorant, it is unfavorable to breathe。Disease sees that heating, body temperature raise 1-2 DEG C, thirsty, dehisces to pant, and stretches neck and faces upward head, breathes and have rale sound, and night, more very the pertussis of suffering from having went out with blood streak sputum, pharyngolaryngeal mucosa hyperemia swelling, coating pseudomembrane, is preced with whisker purple。Seriously suffer from chicken coma slow-witted vertical, paralysis of even twitching, until dead。

Chinese veterinarian thinks, breathes heavily disease and refers to due to diseases caused by exogenous pathogenic factor or internal injury, causes that impairment of dispersing and descending function of the lung, abnormal rising of lung-QI or gas are without being led, and kidney loses to take the photograph and receives, so that a kind of disease that dyspnea etc. are main clinical characteristics。Breathe heavily disease ancient literature also referred to as " breath ", " dyspnea with elevated shoulders ", " upper gas ", " inverse gas ", " dyspnea with rapid and short breath " etc.。"Nei Jing" has more discussion to breathing heavily disease。As " Ling Shu Miraculous Pivot or Divine Axis five is read five and made " is said: " therefore lung patient, dyspnea and flaring of nares。" " Plain Questions lift pain opinion " add: " labor is then panted sweating。" point out to breathe heavily the existing diseases caused by exogenous pathogenic factor of the disease cause of disease, also there is internal injury, pathogenesis also has deficiency and excess not。Additionally, " Plain Questions numbness opinion " cloud: " obstruction of heart-QI person, arteries and veins is obstructed, tired then severe palpitation, sudden and violent upper gas and breathe heavily。" " Plain Questions passages through which vital energy circulates another matter " cloud；" pendant probably, is breathed heavily for liver to some extent。Though " point out and breathe heavily based on lung, it is also related to it dirty。The cause of disease breathing heavily disease is very complicated, exopathogen invasion and attack, improper diet, etc. all can become the cause of disease breathing heavily disease, cause impairment of dispersing and descending function of the lung, abnormal rising of lung-QI or gas without being led, kidney loses and takes the photograph to receive just to become and breathes heavily disease。Exopathogen invasion and attack affection of exogenous wind-cold or the heresy of wind heat, failing timely table dissipates, and heresy is accumulate in lung, stops up resistance lung qi, and lung qi must not be declared and be dropped, thus superinverse is breathed heavily。If kidney yang is weak, the not main water of kidney, pathogenic water to be violated, dry lung insults the heart, abnormal rising of lung-QI, flaccidity of the heart-yang, also can cause and breathe heavily, and this belongs to the time of deficiency complicated with excess。Breathe heavily the sick position of disease, main dirty at lung with kidney, relevant with liver, spleen, the heart。Because of the lung being the dominator of QI, department breathes, outer conjunction fur, the interior canopy for the five internal organs, if exopathogen attacks lung, or violates on its disease of ZANG-organs gas, all can make obstruction of lung-QI, impairment of dispersing and descending function of the lung, breathe unfavorable and cause dyspnea with rapid and short breath, or makes decline of lung-QI, gas become homeless main and dyspnea with rapid and short breath。The kidney being the root of QI, with lung with the cashier taking charge of gas, therefore nephrons is solid, takes the photograph and receives not normal, and gas does not return unit, and negative and positive do not continue mutually, also can QI rising in reverse order in facies pulmonalis cordis for breathing heavily。If disturbing on the turbid pathogenic fluid-retention of insufficiency of the spleen expectorant, or adverse flow of liver-QI is taken advantage of also can cause and is breathed heavily, then the disease for liver spleen affects in lung。Obstruction of heart-QI with dyspnea, then betide when collapse syndrome caused by dyspnea。

The pathologic feature breathing heavily disease has deficiency and excess two class。Excess-dyspnea at lung, stagnation of liver-QI QI rising in reverse order turbid for exopathogen, expectorant, lung stop up pathogen and declare drop unfavorable；Dyspnea due to deficiency is dirty when the lung of duty, kidney two, and because vital essence is not enough, gas yin deficiency consumes and causes the not main gas of lung, failure of the kidney in receiving QI。Therefore the lifting that the basic pathogenesis breathing heavily disease is mechanism of qi is received and paid out not normal, " being real at lung, be empty at kidney "。The mixed person of the state of an illness, often can deficiency in the lower and excess in the upper, simulataneous insufficiency and excessive is also shown in。But in the different phase of PD, give priority between deficiency and excess, or convert mutually。If pneumonopathy and spleen, child-organ disease involving its motherorgan, then temper is also empty, insufficiency of the spleen fortune of losing, and accumulatively wet raise phlegm, upper stain is in lung, obstruction of lung-QI, and cloth is lost in gas Tianjin, and blood is unfavorable, can form the turbid blood stasis of expectorant, and now pathogenesis is based on the domination of pathogen, or the weakened body resistance cross-reference of the domination of pathogen。If protracted course of disease, involving in kidney, its pathogenesis then presents kidney and loses and take the photograph and receive, the time of the excess of the lung of suffering from a deficiency of the kidney of expectorant stasis of blood volt lung。If deficient and weak YANG QI, water is without being led, and pathogenic water overflows, and can go up again icepro cardiopulmonary, and pathogenesis is then excess caused by deficiency, deficient and excessive syndromes appearing together。Chinese veterinarian's categorical identification in terms of causes of disease can be divided into four types: wind cold type cough: morbidity is relatively anxious, tachypnea, and with cough, rhinorrhea with clear discharge, ophthalmic has spumescence secretions, and tracheal strips sends grunt, eyelid swelled, and fear of cold squeezes heap；Phlegm-heat type cough with asthma: morbidity is relatively anxious, coughs dry and comfortable, xerostomia fever of the body, coughs sound pitch and out of breath, and larynx has rale, stretches neck mouth breathing, and expired gas is scorching hot, the thick tears of nose stream, some coughs expectoration often mucus with blood, and some sputums block throat, trachea, causes death by suffocation。The green loose stool of row, some calculus ash water sample loose stools, amount of drinking water increases；Summer-wet type cough with asthma: summer summer heat in season, long summer dampness for contain。When the heresy of heat-damp in summer invades chicken body, suffering from chicken performance spirit depressed, breathe out, some appearance are coughed or have tracheal sound, loss of appetite, and drink is pre-to increase severely, and crop swells, and has loose bowels, and growth of meat chicken is stagnated, the decline of laying hen egg production；Void is coughed: mostly be obstinate disease, and it is faint to suffer from chicken, inappetence, exhales and inhales few more, even dynamic then breathe heavily and have cough, but sound is low, short。

In recent years, the respiratory tract disease of chicken is at home in local popular, and general sickness rate is 30%～40%, and main manifestations is dyspnea, coughs, stridulates。Infecting this after being ill, chick growth slowly or is stagnated, and laying hen egg yield significantly declines, and Mortality phenomenon occurs in some morbidity chicken group, causes serious harm to poultry husbandry, causes bigger economic loss。The environmental factorss such as the pathogenetic reason of chicken respiratory is extremely complex, and the transmitted pathogen such as virus, antibacterial, Mycoplasma is unclean with air, temperature cataclysm are relevant, bring very big difficulty to clinical definite and preventing and treating。This disease is currently mainly treated with vaccine prevention and chemicals and antibiotic etc., and its effect is undesirable。

Summary of the invention

The technical problem to be solved is in that to provide the young additive agent for chicken feed of a kind of curative effect with expectorant cough suppressant and anti-asthmatic, the cold expelling that induces sweat, and has good effect, short treating period, the advantage that has no side effect at treatment chicken wind and cold cough。

In order to solve above-mentioned technical problem, the invention provides a kind of young additive agent for chicken feed, described feed additive includes following raw medicinal material: the Rhizoma Pinelliae, Poria, Rhizoma Zingiberis Recens, Fructus Gleditsia, Fructus Perillae, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Semen Sinapis Albae, Radix Platycodonis, Extract Carnis Bovis, Semen Benincasae, Folium Perillae, Cacumen Tamaricis, Semen Armeniacae Amarum, Flos Inulae, Rhizoma Cynanchi Stauntonii, adenostemma laveniaKuntze, gray gum, Herba Centipedae, platform mushroom, Exocarpium Citrulli, Herba Schizonepetae, Ou Zeqin, Radix Saposhnikoviae and Radix Glycyrrhizae。

Described feed additive is preferably made up of the raw medicinal material of following parts by weight: Rhizoma Pinelliae 10-20 weight portion, Poria 15-25 weight portion, Rhizoma Zingiberis Recens 10-23 weight portion, Fructus Gleditsia 10-20 weight portion, Fructus Perillae 10-18 weight portion, Pericarpium Citri Reticulatae 20-30 weight portion, Cortex Magnoliae Officinalis 10-25 weight portion, Semen Sinapis Albae 10-20 weight portion, Radix Platycodonis 10-19 weight portion, Extract Carnis Bovis 10-18 weight portion, Semen Benincasae 10-20 weight portion, Folium Perillae 10-21 weight portion, Cacumen Tamaricis 10-20 weight portion, Semen Armeniacae Amarum 10-20 weight portion, Flos Inulae 10-20 weight portion, Rhizoma Cynanchi Stauntonii 10-18 weight portion, adenostemma laveniaKuntze 10-30 weight portion, gray gum 10-25 weight portion, Herba Centipedae 10-20 weight portion, platform mushroom 10-20 weight portion, Exocarpium Citrulli 10-19 weight portion, Herba Schizonepetae 10-24 weight portion, Ou Zeqin 10-19 weight portion, Radix Saposhnikoviae 10-20 weight portion and Radix Glycyrrhizae 10-30 weight portion。

Described feed additive is preferably made up of the raw medicinal material of following parts by weight: Rhizoma Pinelliae 13-16 weight portion, Poria 19-23 weight portion, Rhizoma Zingiberis Recens 14-21 weight portion, Fructus Gleditsia 12-17 weight portion, Fructus Perillae 12-15 weight portion, Pericarpium Citri Reticulatae 23-28 weight portion, Cortex Magnoliae Officinalis 15-25 weight portion, Semen Sinapis Albae 12-16 weight portion, Radix Platycodonis 13-19 weight portion, Extract Carnis Bovis 10-15 weight portion, Semen Benincasae 14-20 weight portion, Folium Perillae 14-19 weight portion, Cacumen Tamaricis 12-18 weight portion, Semen Armeniacae Amarum 13-17 weight portion, Flos Inulae 13-20 weight portion, Rhizoma Cynanchi Stauntonii 13-18 weight portion, adenostemma laveniaKuntze 16-25 weight portion, gray gum 13-21 weight portion, Herba Centipedae 13-20 weight portion, platform mushroom 10-16 weight portion, Exocarpium Citrulli 10-14 weight portion, Herba Schizonepetae 14-20 weight portion, Ou Zeqin 13-19 weight portion, Radix Saposhnikoviae 13-18 weight portion and Radix Glycyrrhizae 15-23 weight portion。

Described feed additive is preferably made up of the raw medicinal material of following parts by weight: the Rhizoma Pinelliae 15 weight portion, Poria 21 weight portion, Rhizoma Zingiberis Recens 17 weight portion, Fructus Gleditsia 14 weight portion, Fructus Perillae 14 weight portion, Pericarpium Citri Reticulatae 25 weight portion, Cortex Magnoliae Officinalis 20 weight portion, Semen Sinapis Albae 14 weight portion, Radix Platycodonis 16 weight portion, Extract Carnis Bovis 13 weight portion, Semen Benincasae 16 weight portion, Folium Perillae 16 weight portion, Cacumen Tamaricis 15 weight portion, Semen Armeniacae Amarum 15 weight portion, Flos Inulae 17 weight portion, Rhizoma Cynanchi Stauntonii 14 weight portion, adenostemma laveniaKuntze 21 weight portion, gray gum 16 weight portion, Herba Centipedae 17 weight portion, platform mushroom 13 weight portion, Exocarpium Citrulli 12 weight portion, Herba Schizonepetae 17 weight portion, Ou Zeqin 16 weight portion, Radix Saposhnikoviae 15 weight portion and Radix Glycyrrhizae 17 weight portion。

Described feed additive preferably also includes: rein in the horse back, Herba tetragoniae, Rhizoma Dioscoreae, Ganoderma and Fructus Crataegi。

Described feed additive is preferably made up of the raw medicinal material of following parts by weight: Rhizoma Pinelliae 10-20 weight portion, Poria 15-25 weight portion, Rhizoma Zingiberis Recens 10-23 weight portion, Fructus Gleditsia 10-20 weight portion, Fructus Perillae 10-18 weight portion, Pericarpium Citri Reticulatae 20-30 weight portion, Cortex Magnoliae Officinalis 10-25 weight portion, Semen Sinapis Albae 10-20 weight portion, Radix Platycodonis 10-19 weight portion, Extract Carnis Bovis 10-18 weight portion, Semen Benincasae 10-20 weight portion, Folium Perillae 10-21 weight portion, Cacumen Tamaricis 10-20 weight portion, Semen Armeniacae Amarum 10-20 weight portion, Flos Inulae 10-20 weight portion, Rhizoma Cynanchi Stauntonii 10-18 weight portion, adenostemma laveniaKuntze 10-30 weight portion, gray gum 10-25 weight portion, Herba Centipedae 10-20 weight portion, platform mushroom 10-20 weight portion, Exocarpium Citrulli 10-19 weight portion, Herba Schizonepetae 10-24 weight portion, Ou Zeqin 10-19 weight portion, Radix Saposhnikoviae 10-20 weight portion, Radix Glycyrrhizae 10-30 weight portion, rein in the horse back 10-20 weight portion, Herba tetragoniae 10-20 weight portion, Rhizoma Dioscoreae 15-25 weight portion, Ganoderma 15-30 weight portion and Fructus Crataegi 10-15 weight portion。

Described feed additive is preferably made up of the raw medicinal material of following parts by weight: the Rhizoma Pinelliae 15 weight portion, Poria 20 weight portion, Rhizoma Zingiberis Recens 17 weight portion, Fructus Gleditsia 15 weight portion, Fructus Perillae 14 weight portion, Pericarpium Citri Reticulatae 25 weight portion, Cortex Magnoliae Officinalis 18 weight portion, Semen Sinapis Albae 15 weight portion, Radix Platycodonis 14 weight portion, Extract Carnis Bovis 14 weight portion, Semen Benincasae 15 weight portion, Folium Perillae 16 weight portion, Cacumen Tamaricis 15 weight portion, Semen Armeniacae Amarum 15 weight portion, Flos Inulae 15 weight portion, Rhizoma Cynanchi Stauntonii 14 weight portion, adenostemma laveniaKuntze 20 weight portion, gray gum 17 weight portion, Herba Centipedae 15 weight portion, platform mushroom 15 weight portion, Exocarpium Citrulli 14 weight portion, Herba Schizonepetae 17 weight portion, Ou Zeqin 14 weight portion, Radix Saposhnikoviae 15 weight portion, Radix Glycyrrhizae 20 weight portion, rein in the horse back 15 weight portions, Herba tetragoniae 15 weight portion, Rhizoma Dioscoreae 21 weight portion, Ganoderma 21 weight portion and Fructus Crataegi 12 weight portion。

In order to better realize the preparation method that foregoing invention purpose present invention also offers a kind of young additive agent for chicken feed, described preparation method comprises the following steps:

Step one, all raw medicinal materials are put in proportion in blender stir, mixing, rear feeding pulverizer is pulverized, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add the water relative to its quality 5 ~ 7 times amount, boil 2 ~ 4 hours, steam pressure is 0.6 ~ 1Mpa process, filter, obtain the first filtrate and filtering residue；

Step 2, the filtering residue of acquisition added again the water relative to its quality 5 ~ 7 times amount, boil 2 ~ 4 hours, steam pressure is 0.6Mpa ~ 1Mpa process, is filtrated to get the second filtrate and filtering residue；

Step 3, the first filtrate and the second filtrate being merged, concentration removes moisture, it is thus achieved that dry cream, adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, it is thus achieved that feed additive powder。

The embodiment of the present invention provide technical scheme have the benefit that feed additive of the present invention there is expectorant cough suppressant and anti-asthmatic, the curative effect of the cold expelling that induces sweat, have evident in efficacy at treatment chicken wind-cold type cough, side effect is low, the advantage such as cure rate height, short treating period, not easily recurrence。

Detailed description of the invention

Embodiments provide a kind of young additive agent for chicken feed, including following raw medicinal material: the Rhizoma Pinelliae, Poria, Rhizoma Zingiberis Recens, Fructus Gleditsia, Fructus Perillae, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Semen Sinapis Albae, Radix Platycodonis, Extract Carnis Bovis, Semen Benincasae, Folium Perillae, Cacumen Tamaricis, Semen Armeniacae Amarum, Flos Inulae, Rhizoma Cynanchi Stauntonii, adenostemma laveniaKuntze, gray gum, Herba Centipedae, platform mushroom, Exocarpium Citrulli, Herba Schizonepetae, Ou Zeqin, Radix Saposhnikoviae and Radix Glycyrrhizae；Preferably, feed additive preferably also includes: rein in the horse back, Herba tetragoniae, Rhizoma Dioscoreae, Ganoderma and Fructus Crataegi。

Wherein, the pharmacological property of each raw medicinal material is as follows:

The Rhizoma Pinelliae: pungent, temperature, poisonous；Enter lung, spleen, stomach three warp。" property of medicine opinion ": " expectorant saliva, appetite promoting and the spleen strengthening, anti-nausea, go expectorant in the heart full, and lower lung qi, master coughs knot。" " Japan hanako materia medica ": " controlling and tell food regurgitation, cramp caused by acute vomiting and diarrhea, intestinal abdomen is cold, intermittent fever due to phlegm。" the pungent scattered warm-dryness syndrome of these product is poisonous, main enter taste double enter lung, water of manageing it wets, lowering the adverse flow of QI, and kind taste damp-phlegm of dispelling。Water is wet to be gone, spleen is strong and sputum from disappearing, inverse gas drops then harmonization of the stomach and feeling of fullness vomiting from only, therefore is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the good medicine of dissolving lump and resolving mass。Both cured mainly the abundant expectoration cough with asthma QI rising in reverse order of spleen damp-phlegm heap soil or fertilizer over and around the roots, controlled again the dizziness palpitation and insomnia of criminal on damp-phlegm, and also can control wind-phlegm and tell inverse, the diseases such as headache limb is numb, hemiplegia, facial hemiparalysis。

Poria: sweet, light is flat。GUIXIN warp, lung meridian, spleen channel, kidney channel。Function: diuretic medicine；Diuretics with the action of eliminating dampness。" medication heart method ": " Poria, light energy profit key, sweet with supporing yang, the panacea of dehumidifying is also。The flat YANG invigorating of sweet in the mouth, strengthening the spleen is relieved oedema or abdominal distension through diuresis or purgation, inducing QI of promoting the production of body fluid。" modern study shows that Poria has the effect of enhancing immunity and can many-sided immunologic function be adjusted。Staphylococcus aureus, Bacillus proteus are had significant inhibitory action by Poria。

Rhizoma Zingiberis Recens: Rhizoma Zingiberis Recens refers to the tuber stem of ginger, the purple Rhizoma Zingiberis Recens of another name, Rhizoma Zingiberis Recens, fresh ginger, old ginger。Warm in nature, its distinctive " gingerol " can stimulating gastrointestinal mucosa, make gastrointestinal redness, digestion power strengthens, can effectively treat eat cold and cool food and too much cause abdominal distention, stomachache, diarrhoea, vomiting etc.。After eating Rhizoma Zingiberis Recens, people has the sensation of body heat, this is because it can distend the blood vessels, blood circulation is accelerated, and the pore with promoting opens, and so not only the unnecessary torrid zone can be walked, also internal pathogenic bacteria, cold is together taken out of simultaneously。When health has eaten cold and cool thing, it is subject to drench with rain or stay in air-conditioned room long afterwards, has eaten Rhizoma Zingiberis Recens and just can eliminate in time because human body is trembled with fear the various discomforts remake。

Fructus Gleditsia: pungent, temperature；Enter lung, Liver Channel。Compendium of Material Medica: " Fructus Gleditsia acupuncture controls wind parasite killing, and merit is same with pod, the different ear but its sharp keen through disease is done。" containing flavonoid glycoside, phenols, aminoacid。Flavone compound is fustin (fustin i.e. 3,7,3,4-tetrahydroxy flavanone), fisetin (fisetin i.e. 3,7,3,4-kaempferol), and containing leucocyanidin。Experiment in vivo, has the effect of inhibitory activity to turbid Mus S-180。Decoct flat board burrows method, and staphylococcus aureus and micrococcus catarrhalis are had inhibitory action；The suppression ratio of S-180 is 32.8% by water logging agent 60g/kg gavage。Fructus Gleditsia, for attacking scattered high strict product, is not broken without heavily fortified point, does not dissipate without expectorant, can switch intestinal stasis relieving, to unconsciousness due to blockage of phlegm disease with it, it is possible to emergency。Outer infections head is prominent, will burst when not bursting, and utilize Fructus Gleditsia to break through its head, and to cut for cutter, defeated and dispersed power is quite strong。

Fructus Perillae: pungent, temperature。Return lung, large intestine channel。" book on Chinese herbal medicine converge ": " Fructus Perillae, scattered gas is very prompt, can the upper and lower all gas of profit clearly, Dingchuan expectorant is meritorious, and can lead to two just, except anemofrigid-damp arthralgia。If the deficiency of vital energy and fullness in the chest person, unavailable also, or hold concurrently Shi Yike with tonic。" " Japan hanako materia medica ": " and in homophony, benefit the five internal organs, the therapeutic method to keep the adverse QI flowing downwards, only cholera, vomiting, regurgitation, qi-restoratives labor, fertile strong people, profit defecation, broken knot, disappear five every, antitussive, moisten ambition, eliminating phlegm-retention。" sending down the abnormal ascending QI expectorant, relieving cough and asthma, loosening bowel to relieve constipation。QI rising in reverse order, cough and asthma, dryness of the intestine constipation is stopped up for expectorant。Feeding chicken with the feedstuff containing perilla oil, chicken plasma cholesterol levels can be made to reduce, the mycete in Bacillus proteus, Aspergillus niger, penicillium and nature is all had inhibitory action, the ethanol extraction after defat has anticorrosion and antioxidation。

Pericarpium Citri Reticulatae: bitter, pungent, temperature。Return lung, spleen channel。Energy regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm。For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm。Temperature can circulation of qi promoting, pungent can disperse, bitter and sluice。Saying from lung, then pungent scattered lung qi, hardship lets out lung qi, temperatureization cold, can control abundant expectoration cough with asthma, and gas is stopped up food and stopped；Pericarpium Citri tangerinae goes its words spoken by an actor from offstage person, is referred to as Exocarpium Citri Rubrum, and its arduous taste is heavier, therefore clinic is used primarily on damp eliminating reduces phlegm, when especially abundant expectoration stops up lung, such as conventional patent medicine Juhong Wan etc。Vascular aurantii has row QI of channels and collaterals, goes the effect of meridians phlegm-damp, therefore when being used in the numb limbs and tense tendons of stagnation of QI causing phlegm retention clinically, fits among other Cheng Fang more。Semen Citri Reticulatae has removing obstruction for relieving pain to dry the effect reduced phlegm, therefore is used clinically for hernia pain, the wet main numbness lumbago of Epileptic etc.。Folium Citri tangerinae color is blue or green, has bar to reach the effect of irritability, therefore clinically for the pain over the hypochondriac region, when mastalgia uncomfortable in chest, also fit in side uses more。Cortex Magnoliae Officinalis: bitter, pungent, warm in nature；Return spleen channel, stomach warp, large intestine channel。Function: circulation of qi promoting removing food stagnancy, dampness is removed full, lowering the adverse QI to relieve asthma。Cortex Magnoliae Officinalis and volatile oil bitter in the mouth thereof can stimulate the sense of taste, reflexive cause saliva, gastric secretion, gastrointestinal peristalsis to accelerate, and have stomach invigorating digestion-aid effect。Experiment in vitro proves, the gram negative bacillis such as the gram positive bacterias such as staphylococcus, Hemolytic streptococcus, streptococcus pneumoniae, bordetella pertussis and anthrax bacillus, dysentery bacterium, Bacillus typhi, Salmonella paratyphi, vibrio cholera, escherichia coli, Bacillus proteus, bacillus subtilis are all had antibacterial action by Cortex Magnoliae Officinalis decoct. experiments show that, comparing with other 61 kinds of Chinese medicines, Cortex Magnoliae Officinalis is the strongest to the effect of Staphylococcus albus, bacillus subtilis, escherichia coli and Bacillus typhi。It act as bactericidal action to Staphylococcus albus and bacillus subtilis。

Semen Sinapis Albae: acrid in the mouth, temperature, nontoxic。Enter the warp of liver, spleen, lung, stomach, the heart and collaterals of the uterus。" Japan hanako materia medica ": " control that pathogenic wind toxic is swollen and paralysis, vinegar grind Fu it。Flutterring damage blood stasis, lumbago kidney cold-peace Rhizoma Zingiberis Recens grinds, micro-warm, is coated with patch。Pained, wine vinegar takes it。" Compendium of Material Medica: " Semen Sinapis Albae is pungent can enter lung, and temperature can be dispersed, therefore has the appetizing of promoting the circulation of QI eliminating phlegm, warming middle-JIAO, dissipates the merit of evil of bitterly subsiding a swelling, ward off。" cold air, settling five organs can be removed, by the expectorant of film diaphragm, ward off stealthy gas, the addiction that disappears malaria, drop interests Dingchuan, and profit key improving eyesight, removing blood stasis relieves the pain, and all can prove effective。Energy dissipating can drop, energy complementary energy liter, help all tonics, outstanding kind receipts merit。Mustard flour is used as flavoring agent, makes salivation and amylase activity increase, and makes heart size and heart rate reduce。

Radix Platycodonis: bitter in the mouth, pungent, property is put down。Return lung meridian。There is lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, profit the five internal organs, effect of filling blood, mending five kinds of over strain, foster the spirit of nobility。Cure mainly cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache, aphtha of the mouth and tongue, conjunctival congestion and swelling pain, uroschesis。For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus。" herbal classic " is said: " main chest and hypochondrium such as lancination, abdominal distention, borborygmus are faint, gas of throbbing with fear in terror "。" Japan hanako materia medica " is said: " all gas lower, only cramp caused by acute vomiting and diarrhea, trusted subordinate's distending pain, mend five kinds of over strain, foster the spirit of nobility, and evil removing wards off temperature, qi-restoratives expectorant, broken lump in the abdomen, evacuation of pus of nourishing blood, and mends internal hemorrhage due to trauma and sore throat "。Modern pharmacological research shows, Radix Platycodonis has and eliminates the phlegm and antitussive effect；Hypoglycemic activity；Suppress gastric secretion and antiulcer action；Antiinflammatory action；Calmness, analgesia and refrigeration function。

Extract Carnis Bovis: sweet in the mouth；Warm in nature。Return spleen channel。Function cures mainly: strengthening the spleen and stomach；Fill blood；Moistening the lung and resolving the phlegm。Main asthenia is won thin；Apoplexy is attached undue importance to one thing to the neglect of the other；Phlegm retention mass in the abdomen；Skin sucutaneous nodule。

Semen Benincasae: feeble QI, taste is micro-sweet。Control phlegm-heat cough, lung abscess, acute appendicitis, gonorrhea, edema, beriberi, hemorrhoid, nasal surface wine。After Semen Benincasae water extraction, through dialyzed solution of dialysing to obtain, cause silk for B cell and split agent, have clonal B cell activator activity and adjuvanticity, plaque forming cells can be made to keep count of and significantly increase, present immunologic enhancement。Separate from Semen Benincasae and be purified into 4 components, there is the effect suppressing trypsin vigor。

Folium Perillae: acrid in the mouth warm in nature, have induce sweat, cold expelling, effect of regulating the flow of vital energy and seeking。Suitable in diseases such as cold, fever with aversion to cold, cough, asthma, distension and fullness of the chest and abdomen。Folium Perillae Herb all has significantly high nutritive value, and it has low sugar, high microsteping, high carotene, high mineral element etc.。Containing perillaldehyde, perilla alcohol, menthone, menthol, eugenol, ergomaketon etc. in volatile oil。Defying age element SOD in every milligram of Folium Perillae content up to 106.2 micrograms。It has been investigated that, the each position of Folium Perillae uniformly has good antitumaous effect, especially higher with the effect in blade, oleanolic acid therein is a kind of very strong natural anti-cancer agent, there is the effect of prophylaxis of tumours, there is again the effect of antiinflammatory, calmness, heart tonifying, diuresis, enhancing immunity, blood fat reducing and resistance growth of cancer cells。Folium Perillae can diaphoresis cold expelling to solve pathogenic factor in the exterior, again can promoting the circulation of QI to alleviate the stagnation in middle-JIAO, resolving depression preventing or arresting vomiting, therefore double that see symptoms of emesis uncomfortable in chest to wind and cold table disease, use this product, be very suitable；Or the not smooth symptom of the stagnation of QI is had without table disease, it is also possible to Yu Xuantong。

Cacumen Tamaricis: sweet, pungent, flat。GUIXIN, lung, stomach warp。Function cures mainly: dissipates wind, induces sweat, rash。For measles without adequate eruption, rheumatic arthralgia。

Semen Armeniacae Amarum: bitter, tepor；Slightly poisonous。" Mingyi Bielu ": " almond core, May adopts it。Its two core person kills a person, it is possible to poison Canis familiaris L.。Raw Jin Shanchuangu。" Shennong's Herbal: " main cough with dyspnea is thundered, sore throat, the therapeutic method to keep the adverse QI flowing downwards, galactopoiesis incised wound, bitterly disappointed renal mass。" " property of medicine opinion ": " and control abdomen numbness obstructed, diaphoresis, main epidemic febrile disease。Control spasm in the epigastrium completely pain, except trusted subordinate is unhappy, treat lung qi cough, dyspnea。Enter Radix Asparagi to decoct, moisten cardiopulmonary。Soup, benefit profit information can be made with cheese。Place i.e. dynamic cold air。" relieving cough and asthma, loosening bowel to relieve constipation。Collective Notes to the Canon of Materia medica: " obtain fiery good。Dislike Radix Astragali, Radix Scutellariae, Radix Puerariae。Fear grass。" Semen Armeniacae Amarum hardship temperature lung qi dispersing, loosening bowel to relieve constipation, only it is suitable for the trouble of the excess syndrome such as ailment said due to cold or exposure, dryness of the intestine。All yin deficiency, stagnated fire person, then should not take orally by single medicinal material for a long time。As the disease taboo single medicinal materials such as pulmonary tuberculosis, bronchitis, chronic enteritis, dry cough without phlegm take for a long time。Correct edible Semen Armeniacae Amarum, it is possible to reach promoting the production of body fluid to quench thirst, lung moistening Dingchuan, laxation relieving constipation, reduce effect of intestinal cancer。

Flos Inulae: salty, warm, slightly poisonous；Enter lung, liver, stomach warp。Function expectorant, the therapeutic method to keep the adverse QI flowing downwards, softening the hard mass, row water。" herbal classic ": " main stagnation of QI, fullness in the hypochondrium, palpitation with fear。Dewater, go cold and heat between the five internal organs, invigorating middle warmer, the therapeutic method to keep the adverse QI flowing downwards。" " property of medicine opinion ": " main rib side of body gas, lower cold and heat edema, cure mainly bladder retained water, goes by big abdomen, appetizing, the inverse not lower food of preventing or arresting vomiting。" cure mainly expectorant knot in the heart, the lower distension of the side of body, cough with asthma, singultus, saliva such as shellac varnish, epigastric oppression, eructation unrelieved, extensive abdominal edema。People is had a sensitization by chlorogenic acid, sucks containing after the dust of the plant of chlorogenic acid (as in coffee plant), can pant, dermatitis etc., but can through the effect of intestinal secretion thing after eating, become without allergenic substance, therefore during test sensitinogen, Intradermal method should be used without oral medication。" Amplification on Materia Medica addendum ": " patient relates to void person and should not take more, profit large intestine, guards against it。"

Rhizoma Cynanchi Stauntonii: pungent, bitter, tepor；Return lung meridian。. Tang Materia Medica: " Rhizoma Cynanchi Stauntonii, Ye Siliu, or like Flos Genkwa, height of seedling chi is permitted, on the desert of a raw small piece of land surrounded by water, continent。Root is white, is longer than Herba Asari, sweet in the mouth。Custom takes with wine stain, Zhu Shangqi。Not raw shortcut。The present uses climing survivor, bitter in the mouth, and non-real is also。". " herbal classic is met former ": " Rhizoma Cynanchi Stauntonii, slightly warm compared with Radix Cynanchi Atrati, relatively Herba Asari is slightly flat。Specially search edema due to wind pathogen in lung key, if non-Radix Cynanchi Atrati is salty-cold, specially let out lung, stomach scorching, also do not alter like the pungent of Herba Asari, can control kidney, liver heavy cold also。" lowering the adverse-rising QI to resolve phlegm, cough-relieving。Cough with copious phlegm, asthma。This moral character tepor and not dry strong, be longer than and eliminate the phlegm, drop lung qi with flat cough with asthma。No matter genus is cold belongs to heat, and Exogenous and internal injuries, chronic cough of newly coughing all can use it。

Adenostemma laveniaKuntze: bitter, cold。Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling。For high heat of catching a cold, bronchitis, pharyngolaryngitis, tonsillitis, icterohepatitis；Carbuncle furuncle infections, venom are controlled in external。

Gray gum: hardship pungent, micro-, temperature。Function cures mainly: anti-inflammation and sterilization, expelling phlegm for arresting cough, restrains parasite killing。For preventing influenza, epidemic encephalitis type B。Preventing and treating malaria, enteritis, diarrhoea, dysentery, skin ulceration, ulcerative carbuncle is red and swollen, erysipelas, mastitis, trauma infection contamination, tinea, neurodermatitis。Also can control leptospirosis, tracheitis, cough, maggot, smoked mosquito can be killed。

Herba Centipedae: energy dispersing wind-cold, clearing the nasal passage, cough-relieving, removing toxic substances, antipruritic。" book on Chinese herbal medicine converges and says " cloud: " Herba Centipedae, profit nine orifices, the medicine of stuffy nose relieving gas is also。Its acrid in the mouth is strong, and its gas is pungent smoked, and its property rises and dissipates, and can lead to lung meridian, is up to brains, therefore main clam phlegm dyspnea, gas-tight obstructed, nasal obstruction nasal polyp, and feeling of distension and oppression is unfavorable, goes cataracta in order, and cold-evil, all diseases of wind syndrome of head headache in head, all takes the scattered merit of pungent temperature rise also "。Cough-relieving, antiasthmatic effect: this product volatile oil and ethanol extract part have cough-relieving, eliminate the phlegm, antiasthmatic effect。Volatile oil and ethanol extract part have some cough-relieving, eliminate the phlegm, antiasthmatic effect, and sediment fraction cough suppressing effect is inconspicuous, without phlegm-dispelling functions。Experiment in vitro, tubercule bacillus is had inhibitory action by decoct。Beta-hydroxy-Beta-methyl 1,3-propanedicarboxylic acid (HMG) coenzyme A, calcium channel blocker and gallbladder contraction are have obvious inhibiting effect by herb extract。

Platform mushroom: micro-salty, temperature。Function cures mainly: chase after wind, cold expelling, and relaxing muscles and tendons is active。For lumbago and skelalgia, numb hand and foot, grain does not relax。

Exocarpium Citrulli: sweet, light, cold。It is included into the heart, stomach warp。Function cures mainly+clearing away summer-heat, relieving restlessness of purging heat, diuresis。For summer-heat excessive thirst, oliguria with reddish urine, laryngopharynx swelling and pain, or aphtha of the mouth and tongue, the disease such as edema。

Herba Schizonepetae: acrid in the mouth, micro-hardship, property is micro-wet；Enter lung, Liver Channel。" Japan hanako materia medica ": " profit the five internal organs, removing stagnancy of indigested food and making QI downward, relieving alcoholic intoxication。Raw warm-served food of cooking also simmers tea, and controls wind syndrome of head sweating；The pan-fried violent trauma of controlling of Semen Glycines preparatum is trembled with fear。" " detailed outline ": " dissipating wind heat, refresh oneself, throat, the skin ulcer that disappears swells。Control stiffness of the nape, black flower in order, and raw skin ulcer, cloudy ruined, spit blood, epistaxis, hematochezia, dysentery, metrorrhagia, anal fistula。" main cold, fever, headache, eye itching, cough, laryngopharynx swelling and pain, measles, carbuncle, skin ulcer scabies, puerperal blood faints。For catching a cold, headache, measles, rubella, skin infection from the beginning of。Parch to black treating hematochezia, metrorrhagia, puerperal blood faints。Staphylococcus aureus and diphtheria corynebacterium are had stronger antibacterial action by Herba Schizonepetae decoct。Make fever in rabbits with typhoid fever polyvalent vaccine, give Schizonepeta tenuifolia decoct or ethanol preserved material 2g/kg gavage, it has been found that have faint refrigeration function。Herba Schizonepetae oil can reduce normal rat body temperature；Also having sedation, Herba Schizonepetae oil (0.5ml/kg) is to rabbit gavage, it is seen that its movable minimizing, limb muscle is slightly lax。Herba Schizonepetae oil can be obviously prolonged acetylcholine and Cavia porcellus is caused the incubation period breathed heavily by histamine mixed liquor, reduces the number of animals occurring to twitch；Also the guinea pig tracheal smooth muscle that can anti-acetylcholine or histamine be caused is shunk；Still there is phlegm-dispelling functions。

Ou Zeqin: sweet in the mouth；Property is put down。Function cures mainly: wind-expelling pain-stopping；Blood pressure lowering。Main flu；Headache；Hypertension。

Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature；Enter bladder warp, lung meridian, spleen channel, Liver Channel。" Japan hanako materia medica ": " controlling wind as 36, all labor of man are bad, invigorating middle warmer benefit god, blepharitis marginalis, and arresting lacrimation and paralysis are slow, tonneau the five internal organs GUAN-pulse, five kinds of strain and seven kinds of impairment, thin damage night sweat, vexed body weight, energy tranquilizing the mind, even gaseous pulse。" " Changsha medicine solution ": " network of passing through, by wet excessive, gets round by bribery, and relieve the pain pain, relaxing muscles and tendons arteries and veins, stretches anxious twin, and podomere of living plays paralysis, holds back spontaneous perspiration, night sweat, breaks, metrorrhagia。" function expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic。For affection of exogenous wind-cold, general pain of having a headache, rheumatic arthralgia, joint is ached, and stomachache is had loose bowels, discharging fresh blood stool, tetanus, rubella pruritus, skin infection from the beginning of。Deficiency of YIN-blood, calentura wind symptom person should not use, and blood deficiency convulsion is anxious or has a headache not because ailment said due to cold or exposure person avoids clothes。

Radix Glycyrrhizae: nature and flavor are sweet, flat。Enter spleen, stomach, lung meridian。" herbal classic " is said: " main the five internal organs six mansion cold and heat pathogen, hard muscles and bones, longue meat, times power, incised wound swells, removing toxic substances "。People's cloudy (no) " property of medicine opinion " says: " in main abdomen, cold type of pain, controls infantile convulsion, except distention and fullness in the abdomen；Tonification the five internal organs；Make all poison of drug；Support kidney qi internal injury, make flaccidity；Housewife's human blood drop lumbago；Empty and frequent fever；Add and with it "。Can QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription。Main asthenia lack of appetite, leanness yellowish complexion, shortness of breath and palpitation, loose stool of suffering from abdominal pain, extremity contraction urgency pain, hysteria, cough and asthma, laryngopharynx swelling and pain, ulcerative carbuncle swells and ache, infantile carbuncle, and medicine, alimentary toxicosis。For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong。Western modern medicine haircut is existing, and Radix Glycyrrhizae agent has antiinflammatory and the function of resistance state reflection, therefore in doctor trained in Western medicine clinically mainly as demulcent。Relieving cough, eliminates the phlegm, and treats pharyngalgia laryngitis；Radix Glycyrrhizae or enoxolone have desoxycortone class effect, and chronic adrenocortical hypofunction is had good effects；Glycyrrhiza preparation can promote stomach mucus to be formed and secretion, extends the epithelial cell life-span, has anti-inflammatory activity, be usually used in the treatment of chronic ulcer and duodenal ulcer；The flavone of Radix Glycyrrhizae has antiinflammatory, spasmolytic and antiacid effect；Radix Glycyrrhizae is also one of primary raw material of rendan mini-pills。

Rein in the horse back: bitter, cold。Function cures mainly: lung heat clearing, reduces phlegm, cough-relieving, removing toxic substances。For chronic tracheitis, pulmonary suppuration disease, cough vomiting bloody pus；Hemorrhoid, skin eczema are controlled in external, and rubella is scratched where it itches, furuncle ulcerative carbuncle infections。

Herba tetragoniae: sweet；Micro-pungent；Property is put down。Return lung；Liver；Large intestine channel。Function cures mainly: wind and heat dispersing；Removing toxic substances and promoting subsidence of swelling。The hot conjunctival congestion of main air；Treatment skin ulcer swells and ache；Enteritis；Septicemia；Tumor。

Rhizoma Dioscoreae: sweet in the mouth, property are flat, enter lung, spleen, kidney channel；Not dry oiliness, there are strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will to calm the nerves, effect of life lengthening；Cure mainly that weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI be dry, phlegm dyspnea cough, kidney qi loss, soreness of the waist and knees, lower limb flaccidity is weak, the red disease such as swollen, fat of frequent micturition of quenching one's thirst, seminal emission premature ejaculation, leukorrhagia nebulousurine, skin。Compendium of Material Medica summarizes five big functions " kidney tonifying gas, strengthening the spleen and stomach, stopping leak dysentery, reduce phlegm saliva, moistens skin "。Rhizoma Dioscoreae cook congee or with crystal sugar simmer ripe after take, health is poor, colitis, deficiency of the kidney chronic diseases are all effective in cure。Strengthen the spleen and stomach: treatment weakness of the spleen and stomach, have loose bowels, body is tired, lack of appetite, sweating due to debility。Lung benefiting nourishing kidney: this product is cold not dry, and sweet in the mouth matter is moistened, can treat lung suffer from a deficiency of the kidney damage quench one's thirst, pass out semen, be with inferior disease。It is described as angle's medicine。

Ganoderma: property is sweet, flat。GUIXIN, lung, liver, kidney channel。Cure mainly asthenia, cough, asthma, insomnia, dyspepsia, malignant tumor etc.。Animal pharmacology shows experiment: nervous system is had inhibitory action, blood circulation have blood pressure lowering and strengthen the effect of cardiac contractile force by Ganoderma, and respiratory system is had phlegm-dispelling functions, additionally, also have hepatoprotective, improve immunologic function, antibacterial grade acts on。

Fructus Crataegi: sour in the mouth, sweet, slightly warm in nature, enter spleen, stomach, Liver Channel, for promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, be mainly used to treat accumulation of food in the stomach and intes tine due to indigestion, have loose bowels, dysentery, Fructus Crataegi is the regular supplies for the treatment of dyspepsia, and Fructus Crataegi can increase the secretion of peptic digestion enzyme, facilitating digestion；Dysentery bacterium, bacillus pyocyaneus, staphylococcus aureus etc. had obvious inhibitory action。

Described feed additive is made up of the raw medicinal material of following parts by weight: Rhizoma Pinelliae 10-20 weight portion, Poria 15-25 weight portion, Rhizoma Zingiberis Recens 10-23 weight portion, Fructus Gleditsia 10-20 weight portion, Fructus Perillae 10-18 weight portion, Pericarpium Citri Reticulatae 20-30 weight portion, Cortex Magnoliae Officinalis 10-25 weight portion, Semen Sinapis Albae 10-20 weight portion, Radix Platycodonis 10-19 weight portion, Extract Carnis Bovis 10-18 weight portion, Semen Benincasae 10-20 weight portion, Folium Perillae 10-21 weight portion, Cacumen Tamaricis 10-20 weight portion, Semen Armeniacae Amarum 10-20 weight portion, Flos Inulae 10-20 weight portion, Rhizoma Cynanchi Stauntonii 10-18 weight portion, adenostemma laveniaKuntze 10-30 weight portion, gray gum 10-25 weight portion, Herba Centipedae 10-20 weight portion, platform mushroom 10-20 weight portion, Exocarpium Citrulli 10-19 weight portion, Herba Schizonepetae 10-24 weight portion, Ou Zeqin 10-19 weight portion, Radix Saposhnikoviae 10-20 weight portion and Radix Glycyrrhizae 10-30 weight portion。

Described feed additive is preferably made up of the raw medicinal material of following parts by weight: Rhizoma Pinelliae 13-16 weight portion, Poria 19-23 weight portion, Rhizoma Zingiberis Recens 14-21 weight portion, Fructus Gleditsia 12-17 weight portion, Fructus Perillae 12-15 weight portion, Pericarpium Citri Reticulatae 23-28 weight portion, Cortex Magnoliae Officinalis 15-25 weight portion, Semen Sinapis Albae 12-16 weight portion, Radix Platycodonis 13-19 weight portion, Extract Carnis Bovis 10-15 weight portion, Semen Benincasae 14-20 weight portion, Folium Perillae 14-19 weight portion, Cacumen Tamaricis 12-18 weight portion, Semen Armeniacae Amarum 13-17 weight portion, Flos Inulae 13-20 weight portion, Rhizoma Cynanchi Stauntonii 13-18 weight portion, adenostemma laveniaKuntze 16-25 weight portion, gray gum 13-21 weight portion, Herba Centipedae 13-20 weight portion, platform mushroom 10-16 weight portion, Exocarpium Citrulli 10-14 weight portion, Herba Schizonepetae 14-20 weight portion, Ou Zeqin 13-19 weight portion, Radix Saposhnikoviae 13-18 weight portion and Radix Glycyrrhizae 15-23 weight portion。

Described feed additive can also be made up of the raw medicinal material of following parts by weight: the Rhizoma Pinelliae 15 weight portion, Poria 21 weight portion, Rhizoma Zingiberis Recens 17 weight portion, Fructus Gleditsia 14 weight portion, Fructus Perillae 14 weight portion, Pericarpium Citri Reticulatae 25 weight portion, Cortex Magnoliae Officinalis 20 weight portion, Semen Sinapis Albae 14 weight portion, Radix Platycodonis 16 weight portion, Extract Carnis Bovis 13 weight portion, Semen Benincasae 16 weight portion, Folium Perillae 16 weight portion, Cacumen Tamaricis 15 weight portion, Semen Armeniacae Amarum 15 weight portion, Flos Inulae 17 weight portion, Rhizoma Cynanchi Stauntonii 14 weight portion, adenostemma laveniaKuntze 21 weight portion, gray gum 16 weight portion, Herba Centipedae 17 weight portion, platform mushroom 13 weight portion, Exocarpium Citrulli 12 weight portion, Herba Schizonepetae 17 weight portion, Ou Zeqin 16 weight portion, Radix Saposhnikoviae 15 weight portion and Radix Glycyrrhizae 17 weight portion。

Described feed additive preferably also includes: rein in the horse back, Herba tetragoniae, Rhizoma Dioscoreae, Ganoderma and Fructus Crataegi。

Described feed additive is preferably made up of the raw medicinal material of following parts by weight: Rhizoma Pinelliae 10-20 weight portion, Poria 15-25 weight portion, Rhizoma Zingiberis Recens 10-23 weight portion, Fructus Gleditsia 10-20 weight portion, Fructus Perillae 10-18 weight portion, Pericarpium Citri Reticulatae 20-30 weight portion, Cortex Magnoliae Officinalis 10-25 weight portion, Semen Sinapis Albae 10-20 weight portion, Radix Platycodonis 10-19 weight portion, Extract Carnis Bovis 10-18 weight portion, Semen Benincasae 10-20 weight portion, Folium Perillae 10-21 weight portion, Cacumen Tamaricis 10-20 weight portion, Semen Armeniacae Amarum 10-20 weight portion, Flos Inulae 10-20 weight portion, Rhizoma Cynanchi Stauntonii 10-18 weight portion, adenostemma laveniaKuntze 10-30 weight portion, gray gum 10-25 weight portion, Herba Centipedae 10-20 weight portion, platform mushroom 10-20 weight portion, Exocarpium Citrulli 10-19 weight portion, Herba Schizonepetae 10-24 weight portion, Ou Zeqin 10-19 weight portion, Radix Saposhnikoviae 10-20 weight portion, Radix Glycyrrhizae 10-30 weight portion, rein in the horse back 10-20 weight portion, Herba tetragoniae 10-20 weight portion, Rhizoma Dioscoreae 15-25 weight portion, Ganoderma 15-30 weight portion and Fructus Crataegi 10-15 weight portion。

Described feed additive is preferably made up of the raw medicinal material of following parts by weight: the Rhizoma Pinelliae 15 weight portion, Poria 20 weight portion, Rhizoma Zingiberis Recens 17 weight portion, Fructus Gleditsia 15 weight portion, Fructus Perillae 14 weight portion, Pericarpium Citri Reticulatae 25 weight portion, Cortex Magnoliae Officinalis 18 weight portion, Semen Sinapis Albae 15 weight portion, Radix Platycodonis 14 weight portion, Extract Carnis Bovis 14 weight portion, Semen Benincasae 15 weight portion, Folium Perillae 16 weight portion, Cacumen Tamaricis 15 weight portion, Semen Armeniacae Amarum 15 weight portion, Flos Inulae 15 weight portion, Rhizoma Cynanchi Stauntonii 14 weight portion, adenostemma laveniaKuntze 20 weight portion, gray gum 17 weight portion, Herba Centipedae 15 weight portion, platform mushroom 15 weight portion, Exocarpium Citrulli 14 weight portion, Herba Schizonepetae 17 weight portion, Ou Zeqin 14 weight portion, Radix Saposhnikoviae 15 weight portion, Radix Glycyrrhizae 20 weight portion, rein in the horse back 15 weight portions, Herba tetragoniae 15 weight portion, Rhizoma Dioscoreae 21 weight portion, Ganoderma 21 weight portion and Fructus Crataegi 12 weight portion。

Described preparation method comprises the following steps:

Step one, all raw medicinal materials are put in proportion in blender stir, mixing, rear feeding pulverizer is pulverized, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add the water relative to its quality 5 ~ 7 times amount, boil 2 ~ 4 hours, steam pressure is 0.6 ~ 1Mpa process, filter, obtain the first filtrate and filtering residue；

Step 2, the filtering residue of acquisition added again the water relative to its quality 5 ~ 7 times amount, boil 2 ~ 4 hours, steam pressure is 0.6Mpa ~ 1Mpa process, is filtrated to get the second filtrate and filtering residue；

Step 3, the first filtrate and the second filtrate being merged, concentration removes moisture, it is thus achieved that dry cream, adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, it is thus achieved that feed additive powder。

Embodiment 1 feed additive 1

Embodiments provide a kind of young additive agent for chicken feed, it is made up of the raw medicinal material of parts by weight: the Rhizoma Pinelliae 15 weight portion, Poria 21 weight portion, Rhizoma Zingiberis Recens 17 weight portion, Fructus Gleditsia 14 weight portion, Fructus Perillae 14 weight portion, Pericarpium Citri Reticulatae 25 weight portion, Cortex Magnoliae Officinalis 20 weight portion, Semen Sinapis Albae 14 weight portion, Radix Platycodonis 16 weight portion, Extract Carnis Bovis 13 weight portion, Semen Benincasae 16 weight portion, Folium Perillae 16 weight portion, Cacumen Tamaricis 15 weight portion, Semen Armeniacae Amarum 15 weight portion, Flos Inulae 17 weight portion, Rhizoma Cynanchi Stauntonii 14 weight portion, adenostemma laveniaKuntze 21 weight portion, gray gum 16 weight portion, Herba Centipedae 17 weight portion, platform mushroom 13 weight portion, Exocarpium Citrulli 12 weight portion, Herba Schizonepetae 17 weight portion, Ou Zeqin 16 weight portion, Radix Saposhnikoviae 15 weight portion and Radix Glycyrrhizae 17 weight portion。

Preparation method is as follows:

Step one, all raw medicinal materials are put in proportion in blender stir, mixing, rear feeding pulverizer is pulverized, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add the water relative to its quality 6 times amount, boil 3 hours, steam pressure is 0.8Mpa process, filter, obtain the first filtrate and filtering residue；

Step 2, the filtering residue of acquisition added again the water relative to its quality 6 times amount, boil 3 hours, steam pressure is 0.8Mpa process, is filtrated to get the second filtrate and filtering residue；

Step 3, the first filtrate and the second filtrate being merged, concentration removes moisture, it is thus achieved that dry cream, adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, it is thus achieved that feed additive powder。

Embodiment 2 feed additive 2

Embodiments provide a kind of young additive agent for chicken feed, it is made up of the raw medicinal material of following parts by weight: the Rhizoma Pinelliae 15 weight portion, Poria 20 weight portion, Rhizoma Zingiberis Recens 17 weight portion, Fructus Gleditsia 15 weight portion, Fructus Perillae 14 weight portion, Pericarpium Citri Reticulatae 25 weight portion, Cortex Magnoliae Officinalis 18 weight portion, Semen Sinapis Albae 15 weight portion, Radix Platycodonis 14 weight portion, Extract Carnis Bovis 14 weight portion, Semen Benincasae 15 weight portion, Folium Perillae 16 weight portion, Cacumen Tamaricis 15 weight portion, Semen Armeniacae Amarum 15 weight portion, Flos Inulae 15 weight portion, Rhizoma Cynanchi Stauntonii 14 weight portion, adenostemma laveniaKuntze 20 weight portion, gray gum 17 weight portion, Herba Centipedae 15 weight portion, platform mushroom 15 weight portion, Exocarpium Citrulli 14 weight portion, Herba Schizonepetae 17 weight portion, Ou Zeqin 14 weight portion, Radix Saposhnikoviae 15 weight portion, Radix Glycyrrhizae 20 weight portion, rein in the horse back 15 weight portions, Herba tetragoniae 15 weight portion, Rhizoma Dioscoreae 21 weight portion, Ganoderma 21 weight portion and Fructus Crataegi 12 weight portion。

Described preparation method comprises the following steps:

Step one, all raw medicinal materials are put in proportion in blender stir, mixing, rear feeding pulverizer is pulverized, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add the water relative to its quality 6 times amount, boil 3 hours, steam pressure is 0.8Mpa process, filter, obtain the first filtrate and filtering residue；

Step 2, the filtering residue of acquisition added again the water relative to its quality 6 times amount, boil 3 hours, steam pressure is 0.8Mpa process, is filtrated to get the second filtrate and filtering residue；

Step 3, the first filtrate and the second filtrate being merged, concentration removes moisture, it is thus achieved that dry cream, adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, it is thus achieved that feed additive powder。

Toxicity test

1, cumulative toxicity test report

Select 20 healthy mices, female, male each 10, with the feed additive of the embodiment of the present invention 1 for object, dose design is a phase in every 5 days, each issue dosage respectively 0.10LD50,0.15LD50,0.22LD50,0.34LD50,0.50LD50, the LD50 female, male mice of this sample be 5000m part/k part BW (five dosage is 500,750,1100,1700,2500m part/k part BW)。Within every 5 days, weigh once, adjust dosage, by 0.1ml/10 part BW per os gavage。After 20 days, animal occurs without death condition, off-test, and by ascending-dose to after tested material 20 days, female, buck all occurs without death condition。With the feed additive of embodiment 2 for object, carrying out toxicity test according to the method described above, result such as embodiment 1 is identical。

2, acute toxicity test

Application NIH mice 40, SPF level, male and female half and half, body weight 16～20g, carry out acute toxicity test。Mice is randomly divided into two groups, often group 20, i.e. matched group and administration group, fasting 12 hours before experiment；Feed additive prepared by embodiments of the invention 1 is dissolved in water, (concentration is 6.58g crude drug/ml, maximum concentration) gavage, gavage volume is 5ml/kg(and unit dosage form is 32.9 crude drugs/kg), matched group gives normal saline, within one day, is administered 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record toxic reaction and the death toll of mice。Test result indicate that: compare with matched group, after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal。Therefore the acute toxicity of the feed additive of the embodiment of the present invention 1 is low, clinical drug safety。With the feed additive of embodiment 2 for object, carrying out toxicity test according to the method described above, result such as embodiment 1 is identical。

Contrast test

In December, 2012, the AA broiler morbidity of 1500 21 ages in days of Tai'an, Shandong Province poultry smallholder operating, fall ill two days nearly 1/3rd chicken be initially stream nose, sneeze, ophthalmic have spumescence secretions, full chicken a couple of days occurs that cough, dyspnea, tracheal strips send snore subsequently, feed intake significantly reduces, spirit is poor, is unwilling to walk about, and fear of cold squeezes heap。Pathology cuts open inspection: nasal cavity, tracheal strips have mucus, and air bag substantially thickens, and swelling around the eyes is swollen, can extrude lark grumeleuse。According to suffering from chicken symptom and pathological change diagnosis for wind-cold type cough。

Select 600 ill chickens, be randomly divided into three groups, embodiment group 1, embodiment group 2 and matched group。Embodiment group 1 uses the conventional feed being added with the embodiment of the present invention 1 feed additive, and feed additive accounts for the 5% of feedstuff gross weight, uses 3-5 days；Embodiment group 2 uses the conventional feed being added with the embodiment of the present invention 2 feed additive, and feed additive accounts for the 7% of feedstuff gross weight, uses 3-5 days；Matched group uses enrofloxacin and Buddha's warrior attendant to exhale larynx despot's powder to treat, and in every 1kg feedstuff, interpolation enrofloxacin 55g, Buddha's warrior attendant exhale larynx despot powder 40g, use 3-5 days。Test is 21 days, treats according to different chicken symptom improvement situations, and overall therapeutic, after 5 days, adds up the cure rate of ill chicken, effective percentage, inefficiency and mortality rate。Experimental result is as shown in Table 1 and Table 2。

Treatment standard: all symptoms all disappear, appetite and spirit all recover normal, for recovery from illness；Breathe smooth and easy, tracheal strips snore is inconspicuous, cough with asthma symptom is clearly better, and appetite and spirit are recovered substantially, for effectively；All symptoms all do not change, even dead, for invalid；Wherein effective percentage is the percentage ratio that recovery from illness and effective sum account for sum。

Table 1 overall therapeutic is effect synopsis % after 5 days

Group	Sum	Recovery from illness	Effectively	Invalid	Effective percentage	Mortality rate
							Embodiment group 1	200	153	39	8	96%	2%
Embodiment group 2	200	162	32	6	97%	1.5%
							Matched group	200	129	25	46	77%	11.5%

During each experimental group of table 2 is treated 5 days, recovery from illness compares a % with effective chicken and time

Group	Recovery from illness and effectively sum	1st day	3rd day	5th day
					Embodiment group 1	182	37(20.3%)	124(68.1%)	21(11.5%)
Embodiment group 2	194	42(21.6%)	134(69.1%)	18(9.3%) 10-->
					Matched group	154	18(11.7%)	87(56.5%)	49(31.8%)

Data from table 1 and table 2: the feed additive of the present invention have rapid-action, effective percentage is high, determined curative effect, safety is high, the advantage that has no side effect；After treatment simultaneously five days, the feed additive effective chicken being continuing with to the present invention carries out treatment 1-3 days, effective chicken of embodiment group 1 and embodiment group 2 is all fully recovered, few days after continue to observe, the chicken feed intake of embodiment group 1 and embodiment group 2 recovery from illness is higher than matched group；After experiment terminates, still packet is fed and is delivered for sale to 42 ages in days, and result is added up, and in the chicken that embodiment group 1 and embodiment group were cured in 2 five days, relapse rate is respectively as follows: 6.5% and 5.0%, and in the chicken that matched group was cured in five days, relapse rate is 36.4%。

The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all within the spirit and principles in the present invention, any amendment of making, equivalent replacement, improvement etc., should be included within protection scope of the present invention。

Claims (4)

1. a young additive agent for chicken feed, it is characterized in that, described feed additive includes following raw medicinal material: the Rhizoma Pinelliae, Poria, Rhizoma Zingiberis Recens, Fructus Gleditsia, Fructus Perillae, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Semen Sinapis Albae, Radix Platycodonis, Extract Carnis Bovis, Semen Benincasae, Folium Perillae, Cacumen Tamaricis, Semen Armeniacae Amarum, Flos Inulae, Rhizoma Cynanchi Stauntonii, adenostemma laveniaKuntze, gray gum, Herba Centipedae, platform mushroom, Exocarpium Citrulli, Herba Schizonepetae, Ou Zeqin, Radix Saposhnikoviae, Radix Glycyrrhizae, rein in the horse back, Herba tetragoniae, Rhizoma Dioscoreae, Ganoderma and Fructus Crataegi。

2. young additive agent for chicken feed according to claim 1, it is characterised in that described feed additive is made up of the raw medicinal material of following parts by weight: Rhizoma Pinelliae 10-20 weight portion, Poria 15-25 weight portion, Rhizoma Zingiberis Recens 10-23 weight portion, Fructus Gleditsia 10-20 weight portion, Fructus Perillae 10-18 weight portion, Pericarpium Citri Reticulatae 20-30 weight portion, Cortex Magnoliae Officinalis 10-25 weight portion, Semen Sinapis Albae 10-20 weight portion, Radix Platycodonis 10-19 weight portion, Extract Carnis Bovis 10-18 weight portion, Semen Benincasae 10-20 weight portion, Folium Perillae 10-21 weight portion, Cacumen Tamaricis 10-20 weight portion, Semen Armeniacae Amarum 10-20 weight portion, Flos Inulae 10-20 weight portion, Rhizoma Cynanchi Stauntonii 10-18 weight portion, adenostemma laveniaKuntze 10-30 weight portion, gray gum 10-25 weight portion, Herba Centipedae 10-20 weight portion, platform mushroom 10-20 weight portion, Exocarpium Citrulli 10-19 weight portion, Herba Schizonepetae 10-24 weight portion, Ou Zeqin 10-19 weight portion, Radix Saposhnikoviae 10-20 weight portion, Radix Glycyrrhizae 10-30 weight portion, rein in the horse back 10-20 weight portion, Herba tetragoniae 10-20 weight portion, Rhizoma Dioscoreae 15-25 weight portion, Ganoderma 15-30 weight portion and Fructus Crataegi 10-15 weight portion。

3. young additive agent for chicken feed according to claim 1 and 2, it is characterized in that, described feed additive is made up of the raw medicinal material of following parts by weight: the Rhizoma Pinelliae 15 weight portion, Poria 20 weight portion, Rhizoma Zingiberis Recens 17 weight portion, Fructus Gleditsia 15 weight portion, Fructus Perillae 14 weight portion, Pericarpium Citri Reticulatae 25 weight portion, Cortex Magnoliae Officinalis 18 weight portion, Semen Sinapis Albae 15 weight portion, Radix Platycodonis 14 weight portion, Extract Carnis Bovis 14 weight portion, Semen Benincasae 15 weight portion, Folium Perillae 16 weight portion, Cacumen Tamaricis 15 weight portion, Semen Armeniacae Amarum 15 weight portion, Flos Inulae 15 weight portion, Rhizoma Cynanchi Stauntonii 14 weight portion, adenostemma laveniaKuntze 20 weight portion, gray gum 17 weight portion, Herba Centipedae 15 weight portion, platform mushroom 15 weight portion, Exocarpium Citrulli 14 weight portion, Herba Schizonepetae 17 weight portion, Ou Zeqin 14 weight portion, Radix Saposhnikoviae 15 weight portion, Radix Glycyrrhizae 20 weight portion, rein in the horse back 15 weight portions, Herba tetragoniae 15 weight portion, Rhizoma Dioscoreae 21 weight portion, Ganoderma 21 weight portion and Fructus Crataegi 12 weight portion。

4. the preparation method of the young additive agent for chicken feed according to any one of claim 1-3, it is characterised in that described preparation method comprises the following steps:

Step one, all raw medicinal materials are put in proportion in blender stir, mixing, rear feeding pulverizer is pulverized, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add the water relative to its quality 5 ~ 7 times amount, boil 2 ~ 4 hours, steam pressure is 0.6 ~ 1Mpa process, filter, obtain the first filtrate and filtering residue；

Step 2, the filtering residue of acquisition added again the water relative to its quality 5 ~ 7 times amount, boil 2 ~ 4 hours, steam pressure is 0.6Mpa ~ 1Mpa process, is filtrated to get the second filtrate and filtering residue；

Step 3, the first filtrate and the second filtrate being merged, concentration removes moisture, it is thus achieved that dry cream, adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, it is thus achieved that feed additive powder。