CN101249157A - Traditional Chinese medicine preparation for improving chicken immunity and antioxidant ability - Google Patents
Traditional Chinese medicine preparation for improving chicken immunity and antioxidant ability Download PDFInfo
- Publication number
- CN101249157A CN101249157A CNA2008100708857A CN200810070885A CN101249157A CN 101249157 A CN101249157 A CN 101249157A CN A2008100708857 A CNA2008100708857 A CN A2008100708857A CN 200810070885 A CN200810070885 A CN 200810070885A CN 101249157 A CN101249157 A CN 101249157A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- group
- chicken
- radix
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention provides a traditional Chinese medicine preparation for enhancing chick immunity and antioxidant capacity, relates to a traditional Chinese medicine additive for the health care, antioxidation and immunity enhancement of a chick, and comprises Astragalus root, Atractylodes macrocephaia, radix saposhinikoviae, lanceolata, poria cocos, tangerine peel, hawthorn, and Epimedium. The preparation method comprises the steps of making available raw ingredients, extraction, concentration, starch adding, drying and crushing. The appearance of patent medicine presents luteotestaceous powdery state, the granularity and the bulk density are uniform, the adhesiveness is strong when being added into feeds, and the colour and the luster are concordant without leading the feeds to be dyed and discolored. The traditional Chinese medicine preparation effectively reduces the chick morbidity, enhances the daily growing weight rising of the chickens and feed conversion rate, and has immunological enhancement effect and antioxidation effect.
Description
Technical field
The present invention relates to health care, antioxidation and the raising immunity Chinese medicine additive of the Chinese medicine additive of a kind of chickling, particularly a kind of chickling.
Background technology
The application of antibiotics and chemicals makes the animal husbandry production over nearly 20 years obtain great achievement, but when constantly obtaining the livestock products high yield, has but lighted the red light of food safety.Food-safety problem is the significant problem concerning national economy.In all food pollutions and poisoning, the not science of veterinary drug is used, and it is residual in animal product to become poisonous and harmful substance, even causes the one of the main reasons of serious problems such as environmental pollution and public hazards, brings infringement for consumers in general's health.Simultaneously, in the international trade process, the animal foodstuff Chang Yin " green barrier " of outlet and suffer economically heavy losses.
At above-mentioned unfavorable situation, produce drug residue free meat products, integrate with, break through the trade technology barriers with international standard, increasing export, increasing the benefit has become the tight demand of the high broiler manufacturing enterprise of meat production enterprise, particularly industrialization level.Chinese medicine has multi-faceted adjusting and therapeutical effect, even medium-term and long-term the use because its low toxicity, side effect are little, meets the food safety requirements of increasingly stringent.
Wang Deyun equal to publish an article in " Agricultural University Of Nanjing's journal " the 3rd phase in 2006 " immune synergism of compound Chinese herbal medicinal ingredients and IL 2 and to the influence of chicken cell factor expression ", introduced with epimedium brevicornum polysaccharide add propolis flavone (side 1), the ginsenoside adds astragalus polysaccharides (side 2) and forms 2 compound recipes, respectively add IL-2 and cooperate new city vaccine immunized chicks, respectively at after the immunity the 7th, 14,21 and 28d detect the dynamic change of serum antibody titer with micromethod; Simultaneously 2 compound recipe each minute 3 kinds of dosage are joined in the chicken periphery blood T lymphocyte of cultivation, cultivate respectively 7 and 24h after detect the mRNA change of Expression of lymphocyte IL-2 and IFN-γ with sxemiquantitative RT-PCR method.The result shows, 2 compound recipe lists with or share with IL-2 and all can significantly improve antibody titer, and the immune synergism of compound recipe and IL-2 is not obvious; The high dose of 3 dosage of side 1 and side 2 can significantly promote the gene expression of IL-2, and 3 dosage of 2 compound recipes can significantly promote the gene expression of IFN-γ, have explained compound Chinese herbal medicinal ingredients and the unconspicuous reason of IL-2 immune synergism.
Wang Jundong equals 2002 publish an article in " animal medicine progress " the 4th phase " four Chinese prescriptions are to some Effect on Performance of broiler chicken ", introduced with 125 7 age in days broiler chicken and be divided into 5 groups at random, every group 25, I～IV group is test group, the V group is matched group, matched group is fed basal diet, other the 4 groups daily rations that are fed with 4 Chinese prescriptions of 1% respectively, feed 6 week the back observe their influences to broiler chicken oxidation resistance, immune organ and fertility performance.The result shows: SOD, GSH-Px activity in each test group chicken serum and the tissue are improved than matched group, and MDA content all has decline, and wherein to organize each index all extremely remarkable with matched group difference for III, IV, and III organizes and is better than IV again and organizes; Spleen body ratio is tested I, II, there were significant differences with matched group for the III group, IV group and matched group zero difference; Each test group fertility performance also all is higher than matched group.Experimental result explanation Chinese drug-treated group can improve the oxidation resistance and the immunity of body, and can improve the broiler chicken fertility performance.
Wang Zili equal to publish an article in " Chinese veterinary science " the 6th phase in 2007 " dynamic effect that Chinese medicine compound is expressed chicken immune organ index and IL-2 ", introduced 300 1 age in days male chickens have been divided into 3 groups at random, two groups give prescription I and square II respectively (by Gypsum Fibrosum, Rhizoma Atractylodis, Cortex Phellodendri, Herba Pogostemonis respectively in mass ratio 1: 1: 1: 1 and 0.5: 1: 1: 1 ratio are formed, dosage drinking-water by body weight 0.3mg/kg), matched group is raised according to conventional method.During respectively at chickling the 7th, 21,35,49 ages in days, randomly drawing 5 chickens for every group cuts open extremely, get bursa of Fabricius, spleen, the average positive expression rate of thymus mensuration immune organ exponential sum IL-2, to inquire into the dynamic effect of Chinese medicine compound to chickling immune organ index and IL-2 expression thereof.The result shows, increase along with administration time, prescription I and square II significantly (P＜0.05) or extremely significantly (P＜0.01) improve the average positive expression rate of immune organ index such as bursa of Fabricius, spleen and thymus and IL-2 thereof, square I is to the influence of each immune organ IL-2 positive expression rate significantly (P＜0.05).Confirm that this Chinese medicine compound can promote the chickling cellular immune level, strengthen its non-specific immunity, and promote the growth of immune organ.
Summary of the invention
The objective of the invention is to develop a kind of chickling health care, antioxidation and raising immunity Chinese medicine additive.
The Chinese medicine preparation of raising chicken immunity of the present invention and oxidation resistance is a kind of Chinese powder medicine, is flaxen powder, feeble QI perfume (or spice), sweet and slightly bitter taste.
The Chinese medicine preparation of raising chicken immunity of the present invention and oxidation resistance is made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Radix Codonopsis, Poria, Pericarpium Citri Reticulatae, Fructus Crataegi, Herba Epimedii, and the shared weight percent of each Chinese medicine of distinguishing the flavor of is as follows:
The Radix Astragali 28%～32% Rhizoma Atractylodis Macrocephalae 8%～12% Radix Saposhnikoviae 3%～7%
Radix Codonopsis 18%～22% Poria 8%～12% Pericarpium Citri Reticulatae 3%～7%
Fructus Crataegi 8%～12% Herba Epimedii 8%～10%
Its preparation method comprises raw material, extraction, concentrates, adds starch, drying, pulverizing.Concrete preparation method is as follows:
1, raw material: prescription proportioning mixing for standby use is dried, pressed to the flavor of 8 in above-mentioned prescription medicine;
2, extract: be not higher than under the condition of 0.05Mpa at 55～60 ℃ of temperature, pressure, with above-mentioned raw materials and isopyknic concentration 70%～75% ethanol, continuous extraction twice in the multi-functional extraction unit of Chinese medicine, extraction time is 1h all, merges the crude extract of twice lixiviate gained;
3, concentrate: putting crude extract in concentrator, be that being concentrated into proportion is 1.2～1.3 under the condition of 50～55 ℃ of-0.06～0.07Mpa, temperature in vacuum, must extractum;
4, add starch: press extractum: the weight ratio of starch=1: 1 is added starch in extractum, and stirs;
5, drying: the mixture of putting above-mentioned starch and extractum under the condition of 60～80 ℃ of temperature, is dried to moisture content≤8% in the electric heating hot air circulation drying oven;
6, pulverize: taking out above-mentioned dry thing, to be crushed to fineness with crushing and pelletizing machine be 50～60 orders, is finished product.
The Chinese medicine preparation of raising chicken immunity of the present invention and oxidation resistance, it is Powdered to be dark yellow in appearance, granularity and bulk density are even, it is strong to make an addition to the feedstuff adhesiveness, feedstuff dyeing variable color is coordinated and can not made to color and luster, do not influence the feedstuff primary colors, can use, original effect is all arranged for chicken group's health care and resistance to oxidation and the immunity of growth promotion and raising chicken in the chick growth overall process.Adopt the Radix Astragali, the Rhizoma Atractylodis Macrocephalae and Radix Codonopsis invigorating the spleen and replenishing QI, spleen invigorating consolidating superficial resistance among the present invention; Poria invigorating spleen for diuresis, mind tranquilizing and the heart calming can help Radix Astragali QI invigorating dampness removing; Hawthorn digesting intestinal stasis relieving, the antidiarrheal that is good for the stomach, the Pericarpium Citri Reticulatae dampness of regulating the flow of vital energy.
Belong to the body of the young sun of young the moon at chickling, internal organs are tender and lovely, and shape gas does not fill, the characteristics of the spleen tending to insufficiency usually, and according to air making-up and spleen enlivening, dyspepsia and intestinal stasis relieving, clearing away heat and eliminating dampness principle prescription.Prescription cooperates rigorous, does not have the incompatibility of eighteen incompatible medicaments, nineteen medicaments of mutual restraint, and this Chinese medicine preparation can obviously reduce the chickling sickness rate, improves chicken daily gain and feed conversion rate, has immunological enhancement and antioxidation.
The specific embodiment
In order fully to disclose the Chinese medicine preparation of raising chicken immunity of the present invention and oxidation resistance, be illustrated below in conjunction with embodiment.
Embodiment: the preparation method of a kind of Chinese medicine preparation that improves chicken immunity and oxidation resistance----" spirit of chicken stilbene ".
" spirit of chicken stilbene " is made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Radix Codonopsis, Poria, Pericarpium Citri Reticulatae, Fructus Crataegi, Herba Epimedii, and the shared weight percent of each Chinese medicine of distinguishing the flavor of is as follows:
The Radix Astragali 31% Rhizoma Atractylodis Macrocephalae 10% Radix Saposhnikoviae 5% Radix Codonopsis 20% Poria 10%
Pericarpium Citri Reticulatae 5% Fructus Crataegi 10% Herba Epimedii 9%
Concrete preparation method may further comprise the steps:
1, raw material: prescription proportioning mixing for standby use is dried, pressed to above-mentioned 8 flavor Chinese medicines;
2, extract: under the condition of 60 ℃ of temperature, pressure 0.05Mpa, be 75% ethanol with above-mentioned raw materials and isopyknic concentration, continuous extraction twice in the multi-functional extraction unit of Chinese medicine, extraction time is 1h all, merges the crude extract of twice lixiviate gained;
3, concentrate: with crude extract vacuum cock concentrator, in vacuum be-0.06Mpa, under the condition of 55 ℃ of temperature, being concentrated into proportion is 1.2, must extractum;
4, add starch: press extractum: the weight ratio of starch=1: 1 is added starch in extractum, and stirs;
5, drying: the mixture of putting above-mentioned starch and extractum under the condition of 70 ℃ of temperature, is dried to moisture content 8% in the electric heating hot air circulation drying oven;
6, pulverize: taking out above-mentioned dry thing, to be crushed to fineness with crushing and pelletizing machine be 50 orders, is finished product;
7, packing: above-mentioned ground product is distributed into every bag of 500g, standby.
The raw material that " spirit of chicken stilbene " adopted is as implementing shown in the example.
" spirit of chicken stilbene " function: clearing away heat and eliminating dampness, air making-up and spleen enlivening, enhancing immunity, the various common diseases of prevention chickling.
" spirit of chicken stilbene " cures mainly: the various common diseases of control chickling.
" spirit of chicken stilbene " usage and consumption: press the amount of adding the spirit of 2g chicken stilbene in the per kilogram basal diet and add.
Clinical trial result
One, chicken stilbene spirit Chinese medicine additive fertility performance that high-quality chicken is partly put in a suitable place to breed and butcher Effect on Performance
1. test material and method
1.1 test material adopts chicken stilbene spirit Chinese medicine additive
1.2 the selection of experimental animal and grouping
Herd chicken developing head office chicken house at Jianou City Dong You town Chen Shan,,, be divided into I, II, III, IV group at random according to the principle of " kind is identical, and body weight is suitable, male and female half and half " with 384 of the occasion Gallus jabouilleis of 20 ages in days of brooding, every group of 3 repetitions, each repeats 32.Wherein I, II group is all added chicken stilbene spirit Chinese medicine additive (being called 2 groups in 1 group in Chinese medicine and Chinese medicine) respectively by the amount of 2g/kg and 4g/kg in basal diet; The III group is added colistin 6mg/kg and bacitracin zinc 30mg/kg for adding the antibiotic matched group in basal diet; The IV group is blank group, the basal diet of feeding.The composition and the trophic level of experimental basis daily ration see Table 1.
1.3 feeding and management and immune programme for children
Test chicken adopts the form of herding of partly putting in a suitable place to breed under the same conditions; Put at sports ground daytime, and raise evening in hen house, and stocking density is: be 0.12m in the house
2/ only, house is outer to be 2m
2/ only; The chicken of each test group guarantees free choice feeding, drinking-water, and other daily management is identical.Its immunizing health program sees Table 2.
1.4 mensuration project
For examination chicken 20 ages in days, 70 ages in days, 100 ages in days and try 130 ages in days and repeat to randomly draw 10 empty stomaches from each and claim individual weight, the record daily feed intake is calculated daily gain, feed conversion rate, mortality rate; The off-test same day (130 age in days) repeats male and female from each and respectively randomly draws.
Table 1 test chicken basal diet is formed and trophic level
Annotate: contain fowl in every kilogram of premix material and use compound vitamin 24g, choline chloride 100g, copper sulfate 2.4kg, ferrous sulfate 20g, zinc sulfate 23kg, manganese sulfate 20g, 1% sodium selenite 4.6g, 1% calcium iodate 4g, methionine 100g.
Get 3 empty stomaches and measure carcass rate, half clean thorax rate, complete clean thorax rate, lower limb flesh rate, chest muscle rate; And Carnis Gallus domesticus pH value, shearing force, amino acid content measured.
1.5 statistical processing methods
Test data is used the SPSS12.0 statistical processing software and is carried out one factor analysis of variance and DUNCAN multiple comparisons.
2. result and analysis
2.1 chicken stilbene Siberian cocklebur Chinese medicine additive is to the influence of high-quality chicken fertility performance
2.1.1 the test chicken weightening finish relatively
When 70 ages in days, 100 ages in days, 130 ages in days, 1 group in Chinese medicine, 2 groups in Chinese medicine, antibiotic matched group body weight difference is not significantly (p＞0.05) all.When 70 ages in days, 100 ages in days, 130 ages in days, 2 groups in 1 group in Chinese medicine, Chinese medicine improve 4.64% and 5.45% respectively than blank group body weight, and difference is significantly (p＞0.05) not; 8.10% and 9.42%, significant difference (p＜0.05); 10.60% and 11.92%, difference is (p＜0.01) extremely significantly.1 group in omnidistance average daily gain Chinese medicine and Chinese medicine improve 0.81% and 2.12% than antibiotic matched group respectively for 2 groups, and difference is remarkable (p＞0.05) not; Improve 11.36% and 12.81% than blank group, significant difference (p＜0.05).
The immunizing health program of table 2 test chicken
2.1.2 the omnidistance feedstuff-meat ratio of test chicken relatively
1 group in omnidistance feedstuff-meat ratio Chinese medicine and 2 groups in Chinese medicine and antibiotic matched group compare, and difference is remarkable (p＞0.05) not; Reduce by 11.32% and 12.45% than blank group, difference is (p＜0.01) extremely significantly.Four test group differences of daily ingestion amount are remarkable (p＞0.05) not.Illustrate that this test does not influence the palatability of mixed feed with compound Chinese medicinal additive, can improve the speed of growth and the price of deed of meat.
2.1.3 the omnidistance mortality rate of test chicken relatively
2 groups in Chinese medicine, 1 group in Chinese medicine, antibiotic matched group mortality rate reduce by 2.0,1.0,1.0 percentage points than blank group respectively, and difference is not significantly (p＞0.05) all.
2.2 Chinese medicine additive is to butchering Effect on Performance for the examination chicken
2.2.1 test chicken carcass rate relatively
1 group in Chinese medicine and 2 groups of cock carcass of Chinese medicine rate improve 4.45%, 5.30% and 3.17%, 4.07% difference all not significantly (p＞0.05) than antibiotic group and blank group respectively; 1 group in Chinese medicine and 2 groups of hen carcass of Chinese medicine rate than antibiotic group and blank component you can well imagine high by 4.38%, 6.94% and 0.60%, 3.29%, difference is not significantly (P＞0.05) all.
2.2.2 test chicken half clean thorax rate relatively
2 groups in cock half 1 group in clean thorax rate Chinese medicine and Chinese medicine improve 7.64% (P＜0.05) and 5.20% (P＞0.05) than antibiotic group; Improve 7.54% (P＜0.05) and 5.10% (P＞0.05) than blank group; 1 group in hen half clean thorax rate Chinese medicine has improved 0.22% (P＞0.05) than antibiotic group; 2 groups in 1 group in Chinese medicine and Chinese medicine improve 4.56% and 3.88% difference all not significantly (P＞0.05) than blank group.
2.2.3 the complete clean thorax rate of test chicken relatively
2 groups in 1 group in complete clean thorax rate Chinese medicine of cock and Chinese medicine improve 8.30% (P＜0.05) and 4.53% (P＞0.05) than antibiotic group; Improve 9.03% (P＜0.05) and 5.24% (P＞0.05) than blank group; 2 groups in 1 group in complete clean thorax rate Chinese medicine of hen and Chinese medicine improve 2.92%, 1.21% and 7.26%, 5.48% than antibiotic group and blank group, and difference is not significantly (P＞0.05) all.
2.2.4 test pigeon chest, lower limb flesh rate are relatively
Cock chest muscle rate Chinese medicine has improved 2.16% than antibiotic group for 2 groups; 2 groups of rates of 1 group in Chinese medicine and Chinese medicine improve 2.87% and 5.61% difference all not significantly (P＞0.05) than blank group; 2 groups in 1 group in hen chest muscle rate Chinese medicine and Chinese medicine improve 0.72%, 1.33% and 2.02%, 2.64% than antibiotic and blank group of group, and difference is not significantly (P＞0.05) all.2 groups in 1 group in cock lower limb flesh rate Chinese medicine and Chinese medicine than antibiotic group and blank component you can well imagine high by 0.71%, 0.57% and 2.22%, 2.08%, difference is not significantly (P＞0.05) all; 2 groups in 1 group in hen lower limb flesh rate Chinese medicine and Chinese medicine improve 0.71%, 1.73% and 1.39% (P＞0.05), 2.42% than antibiotic group and blank group, and difference is not significantly (P＞0.05) all.Illustrate that this Chinese medicine additive can improve the performance of butchering of broiler.
2.3 chicken stilbene Siberian cocklebur Chinese medicine additive is to the influence of test chicken chest muscle pH value and shearing force
2.3.1 test chicken chest muscle rate pH relatively
Four groups of test male and female thoracic muscle pH value relatively, difference is not significantly (P＞0.05) all.
2.3.2 test chicken chest muscle rate shearing force relatively
The shearing force of cock chest muscle, 2 groups in 1 group in Chinese medicine and Chinese medicine with than antibiotic group relatively, difference is not significantly (P＞0.05) all; 2 groups in 1 group in Chinese medicine and Chinese medicine you can well imagine high 58.23% and 98.26% than blank component, and difference is significantly (p＜0.05) all.2 groups in 1 group in shearing force Chinese medicine of hen chest muscle and Chinese medicine than antibiotic group and blank component you can well imagine high by 67.12%, 37.54% and 71.60%, 41.23%, difference is significantly (p＜0.05) all.Illustrate that chicken stilbene Siberian cocklebur Chinese medicine additive has certain influence to the shearing force and the quality of broiler muscle.
2.4 Chinese medicine additive is to the influence of amino acid content in the muscle
1 group in Chinese medicine is compared with the blank group with the antibiotic group with aspartic acid, threonine, serine, glutamic acid, glycine, alanine, cystine, isoleucine, leucine, tyrosine, lysine, histidine, the acid of cattle semi-annular jade pendant, methionine, the total amount of 2 groups in Chinese medicine, and difference is not remarkable.Illustrate that chicken stilbene Siberian cocklebur Chinese medicine additive is not remarkable to the influence of the amino acid content in the Carnis Gallus domesticus, kept original nutritional labeling of high-quality Carnis Gallus domesticus.
Two, the Carnis Gallus domesticus mensuration up to standard of chicken stilbene Siberian cocklebur Chinese medicine additive test group high-quality chicken
1. test material and method
1,2 groups of test chickens of Chinese medicine are raised 130 ages in days, by the relevant operation of butchering, test chicken are carried out blood-letting, loses hair or feathers, opens hall, separates operations such as breast, lower limb flesh and butcher.Cut chest muscle 100g, pack properly with newly purchasing nonpoisonous packing film behind the rejecting fascia, be sent to Fujian Province Central Inspect Station (country processed food supervision and inspection center) of reservation immediately, carry out the mensuration of the nuisanceless relevant item of Carnis Gallus domesticus.
2. chicken stilbene spirit Chinese medicine additive test Carnis Gallus domesticus NY5034-2001 standard and practical measurement situation (country's processed food supervision and inspection center survey report) see Table 3.
Obviously find out in the table, chicken stilbene spirit Chinese medicine additive test group is butchered test result, not only reach Carnis Gallus domesticus NY5034-2001 standard fully, and in the project of oxytetracycline, chlortetracycline, sulfonamides, enrofloxacin, ciprofloxacin for not detecting the actual GB standard that reaches of this result.The safe Carnis Gallus domesticus that chicken stilbene spirit Chinese medicine additive can obtain higher standard is used in prompting, effectively improves the quality and the taste of Carnis Gallus domesticus simultaneously.
Table 3 Chinese medicine additive test Carnis Gallus domesticus practical measurement result
| Sequence number | Inspection item | Unit | Specification requirement | Assay | Individual event is judged | Remarks (detection limit) |
| 1 | Arsenic (in As) | mg/kg | ≤0.5 | ＜0.1 | Qualified | / |
| 2 | Plumbous (in Pb) | mg/kg | ≤0.1 | 0.1 | Qualified | / |
| 3 | Hydrargyrum (in Hgy) | mg/kg | ≤0.05 | ＜0.05 | Qualified | / |
| 4 | Cadmium (in Cd) | mg/kg | ≤0.1 | ＜0.1 | Qualified | / |
| 5 | Oxytetracycline | mg/kg | ≤0.10 | Do not detect | Qualified | 5×10 -2 |
| 6 | Chlortetracycline | mg/kg | ≤0.10 | Do not detect | Qualified | 5×10 -2 |
| 7 | Sulfonamides (in the sulfonamides total amount) | mg/kg | ≤0.10 | Do not detect | Qualified | 1×10 -2 |
| 8 | Enrofloxacin | mg/kg | ≤0.10 | Do not detect | Qualified | 1×10 -2 |
| 9 | Ciprofloxacin | mg/kg | ≤0.10 | Do not detect | Qualified | 2×10 -2 |
Claims (3)
1, a kind of Chinese medicine preparation that improves chicken immunity and oxidation resistance is characterized in that being made up of the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Saposhnikoviae, Radix Codonopsis, Poria, Pericarpium Citri Reticulatae, Fructus Crataegi, Herba Epimedii, and the shared weight percent of each medicine of distinguishing the flavor of is as follows:
The Radix Astragali 28%～32% Rhizoma Atractylodis Macrocephalae 8%～12% Radix Saposhnikoviae 3%～7%
Radix Codonopsis 18%～22% Poria 8%～12% Pericarpium Citri Reticulatae 3%～7%
Fructus Crataegi 8%～12% Herba Epimedii 8%～10%
2, a kind of Chinese medicine preparation that improves chicken immunity and oxidation resistance according to claim 1, the shared weight percent of medicine that it is characterized in that respectively distinguishing the flavor of is as follows:
The Radix Astragali 31% Rhizoma Atractylodis Macrocephalae 10% Radix Saposhnikoviae 5% Radix Codonopsis 20%
Poria 10% Pericarpium Citri Reticulatae 5% Fructus Crataegi 10% Herba Epimedii 9%
3, a kind of preparation method that improves the Chinese medicine preparation of chicken immunity and oxidation resistance is characterized in that may further comprise the steps:
(1) raw material: adopt claim 1 or 2 described 8 flavor Chinese medicine and prescription proportionings, with the Chinese medicine oven dry, and by its prescription proportioning mixing for standby use;
(2) extract: be not higher than under the condition of 0.05Mpa at 55～60 ℃ of temperature, pressure, with above-mentioned raw materials and isopyknic concentration 70%～75% ethanol, continuous extraction twice in the multi-functional extraction unit of Chinese medicine, extraction time is 1h all, merges the crude extract of twice lixiviate gained;
(3) concentrate: putting crude extract in concentrator, be that being concentrated into proportion is 1.2～1.3 under the condition of 50～55 ℃ of-0.06～0.07Mpa, temperature in vacuum, must extractum;
(4) add starch: press extractum: the weight ratio of starch=1: 1 is added starch in extractum, and stirs;
(5) drying: the mixture of putting above-mentioned starch and extractum under the condition of 60～80 ℃ of temperature, is dried to moisture content≤8% in the electric heating hot air circulation drying oven;
(6) pulverize: taking out above-mentioned dry thing, to be crushed to fineness with crushing and pelletizing machine be 50～60 orders.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100708857A CN101249157B (en) | 2008-04-11 | 2008-04-11 | Traditional Chinese medicine preparation for improving chicken immunity and antioxidant ability |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008100708857A CN101249157B (en) | 2008-04-11 | 2008-04-11 | Traditional Chinese medicine preparation for improving chicken immunity and antioxidant ability |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101249157A true CN101249157A (en) | 2008-08-27 |
| CN101249157B CN101249157B (en) | 2010-12-08 |
Family
ID=39952867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008100708857A Expired - Fee Related CN101249157B (en) | 2008-04-11 | 2008-04-11 | Traditional Chinese medicine preparation for improving chicken immunity and antioxidant ability |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101249157B (en) |
Cited By (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102308929A (en) * | 2011-09-09 | 2012-01-11 | 上海交通大学 | Chinese herbal medicine feed additive for enhancing chicken immunity, preparation method and feed |
| CN101744105B (en) * | 2009-12-25 | 2012-03-14 | 天津市畜牧兽医研究所 | Compound feed containing white melon seed hull powder for laying-period breeding geese |
| CN103083414A (en) * | 2011-10-27 | 2013-05-08 | 天津生机集团股份有限公司 | Traditional Chinese medicine composition used for enhancing chicken immunity |
| CN103127284A (en) * | 2013-03-04 | 2013-06-05 | 董瑞 | Xianqi formula capable of strengthening yang-qi and healthy energy and preparation method |
| CN103283988A (en) * | 2013-01-29 | 2013-09-11 | 广州格拉姆生物科技有限公司 | Lactoferricin feed additive |
| CN103315161A (en) * | 2013-07-15 | 2013-09-25 | 曾勇 | Special feed additive for broiler chick |
| CN103404708A (en) * | 2013-08-26 | 2013-11-27 | 山东新希望六和集团有限公司 | Traditional Chinese medicine composition for improving immunity of poultry in brood time and preparation method thereof |
| CN103734508A (en) * | 2013-12-12 | 2014-04-23 | 济南新起点医药科技有限公司 | Feed for improving immunity of laying hens |
| CN103860656A (en) * | 2012-12-11 | 2014-06-18 | 洛阳惠中兽药有限公司 | Traditional Chinese medicinal composition, and preparation method and application thereof |
| CN104324153A (en) * | 2014-10-22 | 2015-02-04 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for improving immunity of animals and preparation method thereof |
| CN104489416A (en) * | 2015-01-14 | 2015-04-08 | 安徽科技学院 | Immunity-enhancing high-yield Chinese herb feed additive for broiler chicken |
| CN104758416A (en) * | 2014-12-10 | 2015-07-08 | 北京康华远景科技股份有限公司 | Botanical drug composition capable of improving immunity of laying hens and preparation method thereof |
| CN105028925A (en) * | 2015-08-06 | 2015-11-11 | 合肥绿野安品生态农业科技有限公司 | Chinese herbal medicine feed nutrient for poultry |
| CN105341330A (en) * | 2015-07-31 | 2016-02-24 | 河北北方牧业科技有限公司 | Traditional Chinese medicine fattening additive |
| CN105581048A (en) * | 2016-01-09 | 2016-05-18 | 黄庆梅 | Feed additive for enhancing immunity of chicks |
| CN105688171A (en) * | 2014-03-20 | 2016-06-22 | 山东新希望六和集团有限公司 | Chicken feed additive and preparation method thereof |
| CN106581670A (en) * | 2016-12-11 | 2017-04-26 | 钦州学院 | Inactivated pentavaccine for flounder paralichthys and preparation method of inactivated pentavaccine |
| CN108200884A (en) * | 2018-04-17 | 2018-06-26 | 金寨县黑凤凰农业科技开发有限公司 | The new method that Dabie Mountain chicken genetic quality continues |
| CN108524717A (en) * | 2018-07-03 | 2018-09-14 | 厦门法茉维特医药科技有限公司 | A kind of peaceful QI invigorating Chinese traditional medicine composition and preparation method thereof for animals of dwelling |
| CN109021135A (en) * | 2018-07-27 | 2018-12-18 | 四川农业大学 | A kind of codonopsis pilosula var. modesta polysaccharide formulation and preparation method thereof |
| CN114209769A (en) * | 2021-12-30 | 2022-03-22 | 河南金大众生物工程有限公司 | Natural plant composition for improving animal immunity and application thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100364441C (en) * | 2006-04-07 | 2008-01-30 | 张永玉 | Chinese medicinal herb feed additive used for aquaculture and its use method |
| CN100581378C (en) * | 2006-08-01 | 2010-01-20 | 济南亿民动物药业有限公司 | Method for preparing fermented Chinese herbal medicine preparations for feed |
-
2008
- 2008-04-11 CN CN2008100708857A patent/CN101249157B/en not_active Expired - Fee Related
Cited By (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101744105B (en) * | 2009-12-25 | 2012-03-14 | 天津市畜牧兽医研究所 | Compound feed containing white melon seed hull powder for laying-period breeding geese |
| CN102308929A (en) * | 2011-09-09 | 2012-01-11 | 上海交通大学 | Chinese herbal medicine feed additive for enhancing chicken immunity, preparation method and feed |
| CN102308929B (en) * | 2011-09-09 | 2013-02-06 | 上海交通大学 | Chinese herbal medicine feed additive for enhancing chicken immunity, preparation method and feed |
| CN103083414A (en) * | 2011-10-27 | 2013-05-08 | 天津生机集团股份有限公司 | Traditional Chinese medicine composition used for enhancing chicken immunity |
| CN103860656A (en) * | 2012-12-11 | 2014-06-18 | 洛阳惠中兽药有限公司 | Traditional Chinese medicinal composition, and preparation method and application thereof |
| CN103283988A (en) * | 2013-01-29 | 2013-09-11 | 广州格拉姆生物科技有限公司 | Lactoferricin feed additive |
| CN103127284A (en) * | 2013-03-04 | 2013-06-05 | 董瑞 | Xianqi formula capable of strengthening yang-qi and healthy energy and preparation method |
| CN103315161A (en) * | 2013-07-15 | 2013-09-25 | 曾勇 | Special feed additive for broiler chick |
| CN103315161B (en) * | 2013-07-15 | 2014-03-12 | 曾勇 | Special feed additive for broiler chick |
| CN103404708A (en) * | 2013-08-26 | 2013-11-27 | 山东新希望六和集团有限公司 | Traditional Chinese medicine composition for improving immunity of poultry in brood time and preparation method thereof |
| CN103404708B (en) * | 2013-08-26 | 2015-01-21 | 山东新希望六和集团有限公司 | Traditional Chinese medicine composition for improving immunity of poultry in brood time and preparation method thereof |
| CN103734508A (en) * | 2013-12-12 | 2014-04-23 | 济南新起点医药科技有限公司 | Feed for improving immunity of laying hens |
| CN105688171A (en) * | 2014-03-20 | 2016-06-22 | 山东新希望六和集团有限公司 | Chicken feed additive and preparation method thereof |
| CN104324153A (en) * | 2014-10-22 | 2015-02-04 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for improving immunity of animals and preparation method thereof |
| CN104758416A (en) * | 2014-12-10 | 2015-07-08 | 北京康华远景科技股份有限公司 | Botanical drug composition capable of improving immunity of laying hens and preparation method thereof |
| CN104758416B (en) * | 2014-12-10 | 2018-08-21 | 北京康华远景科技股份有限公司 | A kind of plant drug composition improving immunity of layer chicken |
| CN104489416A (en) * | 2015-01-14 | 2015-04-08 | 安徽科技学院 | Immunity-enhancing high-yield Chinese herb feed additive for broiler chicken |
| CN105341330A (en) * | 2015-07-31 | 2016-02-24 | 河北北方牧业科技有限公司 | Traditional Chinese medicine fattening additive |
| CN105028925A (en) * | 2015-08-06 | 2015-11-11 | 合肥绿野安品生态农业科技有限公司 | Chinese herbal medicine feed nutrient for poultry |
| CN105581048A (en) * | 2016-01-09 | 2016-05-18 | 黄庆梅 | Feed additive for enhancing immunity of chicks |
| CN106581670A (en) * | 2016-12-11 | 2017-04-26 | 钦州学院 | Inactivated pentavaccine for flounder paralichthys and preparation method of inactivated pentavaccine |
| CN108200884A (en) * | 2018-04-17 | 2018-06-26 | 金寨县黑凤凰农业科技开发有限公司 | The new method that Dabie Mountain chicken genetic quality continues |
| CN108524717A (en) * | 2018-07-03 | 2018-09-14 | 厦门法茉维特医药科技有限公司 | A kind of peaceful QI invigorating Chinese traditional medicine composition and preparation method thereof for animals of dwelling |
| CN109021135A (en) * | 2018-07-27 | 2018-12-18 | 四川农业大学 | A kind of codonopsis pilosula var. modesta polysaccharide formulation and preparation method thereof |
| CN114209769A (en) * | 2021-12-30 | 2022-03-22 | 河南金大众生物工程有限公司 | Natural plant composition for improving animal immunity and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101249157B (en) | 2010-12-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101249157B (en) | Traditional Chinese medicine preparation for improving chicken immunity and antioxidant ability | |
| CN101259233B (en) | Traditional Chinese medicine preparation for improving adult chicken immunity and antioxidant ability | |
| CN102450523B (en) | Feed for meat ducks and traditional Chinese medicine additive thereof | |
| CN102754753B (en) | Feed for improving growth performances of broiler chickens and preparation method thereof | |
| CN101926411B (en) | Heartleaf houttuynia herb livestock and poultry feed additive and preparation method thereof | |
| CN100502907C (en) | Health-preserving and growth-promoting Chinese medicinal additive for pig | |
| CN102578397B (en) | Chinese herbal medicine feed additive, Chinese herbal medicine mixed feed and preparation method thereof | |
| CN102960547B (en) | Flavor type livestock and poultry feed additive | |
| CN102845638B (en) | Duck feed capable of preventing and treating avian influenza and Chinese herbal additive used therein | |
| CN103750063B (en) | Traditional Chinese herbal medicine composite cattle feed capable of enhancing immunity and improving meat quality | |
| CN102308929A (en) | Chinese herbal medicine feed additive for enhancing chicken immunity, preparation method and feed | |
| CN101711826B (en) | Traditional Chinese medicine composite for improving poulard productivity and application thereof | |
| CN103750064B (en) | Chinese herbal medicine compound pig feed with effects of enhancing immunity and improving meat quality | |
| CN106360107A (en) | Disease-prevention health feed for loaches and preparation method thereof | |
| CN106036167A (en) | Chicken feed | |
| CN103750067B (en) | Traditional Chinese herbal medicine composite chicken feed capable of enhancing immunity and improving meat quality | |
| CN106305613A (en) | Culture method of nuisanceless meat pigeons | |
| CN108771016A (en) | One boar Chinese herbal feed additive and its application | |
| CN103750066B (en) | Chinese herbal medicine compound duck feed with effects of enhancing immunity and improving meat quality | |
| CN105028925A (en) | Chinese herbal medicine feed nutrient for poultry | |
| CN109198203A (en) | A kind of pig-breeding method | |
| CN106360066A (en) | Turkey feed | |
| CN103892048A (en) | Feed additive with functions of soothing nerves, enhancing immunity and promoting growth for piglet and preparation method and application of additive | |
| CN103263538B (en) | Traditional Chinese medicine combination with nourishing, anti-inflammation, antidiarrheal, hemostatic and analgesic effects for livestock and preparation method thereof | |
| CN102824630B (en) | Pharmaceutical composition for treating chicken proventriculitis and preparation method of pharmaceutical composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170703 Address after: 365500 Shaxian County Jinsha Jinsha hi tech Development Zone, Fujian, Sanming City Patentee after: Fujian Wei ear Animal Pharmaceutical Co. Ltd. Address before: 350002 intellectual property management office, Fujian Agriculture And Forestry University, Jinshan, Fujian, Fuzhou Patentee before: Fujian Agricultural and Forestry University |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20101208 Termination date: 20200411 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |