CN105688168A - Pet all-in-one insect expelling spray and preparation method thereof - Google Patents

Pet all-in-one insect expelling spray and preparation method thereof Download PDF

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Publication number
CN105688168A
CN105688168A CN201610163533.0A CN201610163533A CN105688168A CN 105688168 A CN105688168 A CN 105688168A CN 201610163533 A CN201610163533 A CN 201610163533A CN 105688168 A CN105688168 A CN 105688168A
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pet
extract
spray
anthelmintic
fipronil
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CN201610163533.0A
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Inventor
丁伟
刘丽
陆松侠
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Shanghai Shenya Animal Health Products Fuyang Co Ltd
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Shanghai Shenya Animal Health Products Fuyang Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention relates to a pet all-in-one insect expelling spray and a preparation method thereof, and belongs to the field of pet articles. The pet all-in-one insect expelling spray is prepared from the following raw materials in percentage by weight: 30% to 60% of distilled water, 3% to 7% of olive oil, 8% to 12% of propylene glycol, 5% to 8% of glycerinum, 8% to 12% of high-quality castor oil, 3% to 5% of aloe extract, 3% to 5% of ginger extract, 0.5% to 1% of borneol, 0.3% to 0.7% of eucalyptus oil, 0.12% to 0.15% of pyrethroid, 0.2% to 0.5% of abamectin, 0.1% to 0.3% of Fipronil, 0.5% to 0.7% of N-(2-ethylhexyl)-5-norbornene-2,3-dicarboximide, 1% to 2% of terbinafine hydrochloride, 10% to 14% of ethyl alcohol, and 1% to 2% of camphor extract. The pet all-in-one insect expelling spray has the advantages that by adding multiple plant extracts, the bacteria infection of the pet can be decreased, the damaged hair follicles are restored, the growth of hair follicles is promoted, and the pet skin is effectively protected; various types of parasites at the surface of the pet can be effectively removed, and the attack by the parasites can be prevented; the plant extraction is safe and is free from irritation, so that the pet is cared in all directions.

Description

Anthelmintic spray that a kind of house pet is unified by multiple-effect and preparation method thereof
Technical field
The present invention relates to anthelmintic spray that a kind of house pet multiple-effect unifies and preparation method thereof, belong to pet supplies field。
Background technology
Present living standard improves; the house pet with hairs such as pet feeding cat, Canis familiaris L. is also more and more; but it is because house pet to pay attention to hygiene as the mankind; so various harmful parasites such as louse, flea, acarid often occur with house pet; these parasites not only can bring disease and misery to house pet; also can by disease propagation to the mankind, so wanting keeping a pet of happiness, anthelmintic and pre-insect protected are inevitable。The method of anthelmintic and product have a lot, have and directly eat to house pet, have the bath gel etc. of anthelmintic, but the medicine side effect eaten is relatively big, is not as safety；Bath gel neither be easily quick to pet bathing, and is likely to serve side effect to pet hair and skin tape through conventional。It addition, the insect repellent products effect on market is single, and only focus on anthelmintic, have ignored the nursing to house pet。
Summary of the invention
It is an object of the invention to solve the weak point that above-mentioned prior art exists, it is provided that a kind of safely and effectively can conveniently drive away parasite with house pet and the impaired hair follicle of pet skin, maintenance anthelmintic spray promoting pet hair growth and preparation method thereof can be protected。
The present invention is achieved by the following technical solutions:
The anthelmintic spray that a kind of house pet is unified by multiple-effect, it is characterized in that is made up of following raw material by weight ratio: distilled water 30%-60%, olive oil 3%-7%, propylene glycol 8%-12%, glycerol 5%-8%, high-quality Oleum Ricini 8%-12%, Aloe extract 3%-5%, Rhizoma Zingiberis Recens extract 3%-5%, Borneolum Syntheticum 0.5%-1%, eucalyptus oil 0.3%-0.7%, chrysanthemum esters 0.12%-0.15%, avilamycin 0.2%-0.5%, Fipronil 0.1%-0.3%, Octacide 264 0.5%-0.7%, terbinafine HCl 1%-2%, ethanol 10%-14%, Camphora extract 1%-2%；
The anthelmintic spray that described a kind of house pet is unified by multiple-effect, is made up of the raw material of following optimal proportion by weight: distilled water 46%, olive oil 4%, propylene glycol 9%, glycerol 6%, high-quality Oleum Ricini 9%, Aloe extract 4%, Rhizoma Zingiberis Recens extract 4.5%, Borneolum Syntheticum 0.63%, eucalyptus oil 0.6%, chrysanthemum esters 0.12%, avilamycin 0.15%, Fipronil 0.2%, Octacide 264 0.6%, terbinafine HCl 2%, ethanol 12%, Camphora extract 1.2%；
The preparation method of the anthelmintic spray that a kind of house pet is unified by multiple-effect, it is characterized in that and comprises the following steps:
(1) chrysanthemum esters, avilamycin, Fipronil, Octacide 264, terbinafine HCl, Borneolum Syntheticum being mixed with ethanol, propylene glycol, high-quality Oleum Ricini, 55-65 DEG C of heating and melting, mix homogeneously forms mixture；
(2) remaining each several part is added in (1) mixture, be eventually adding distilled water。In process always under 55-65 DEG C of water-bath state, namely mix homogeneously obtains medicinal liquid；
(3) medicinal liquid is distributed in watering can, obtains product。
The anthelmintic spray that a kind of house pet of the present invention is unified by multiple-effect, adds plants essential oil and various plants extract, it is possible to reduce house pet is infected by bacterial, and repairs impaired hair follicle and promotes hair growth, effectively protects pet skin。It is possible not only to the effectively removal various parasite of house pet body surface, it is also possible to prevent various parasitic infringement。Plant extract is safe and non-stimulating, has been truly realized the omnibearing care of house pet, not only focuses on anthelmintic, and focuses on protection pet skin and healthy。Only need to push pet hair aside sprays a few spray, and rubbing hair gently can effective anthelmintic, the effectively various parasitic infringement of prevention。
Detailed description of the invention
The specific embodiment of the present invention given below, is used for the composition of the present invention is described in further detail。
Embodiment 1
The anthelmintic spray that a kind of house pet of the present embodiment is unified by multiple-effect, is made up of following raw material by weight ratio: distilled water 40%, olive oil 6%, propylene glycol 12%, glycerol 8%, high-quality Oleum Ricini 10%, Aloe extract 4%, Rhizoma Zingiberis Recens extract 3.4%, Borneolum Syntheticum 0.7%, eucalyptus oil 0.3%, chrysanthemum esters 0.12%, avilamycin 0.25%, Fipronil 0.2%, Octacide 264 0.65%, terbinafine HCl 1%, ethanol 12%, Camphora extract 1.38%。
Embodiment 2
The anthelmintic spray that a kind of house pet of the present embodiment is unified by multiple-effect, is made up of following raw material by weight ratio: distilled water 46%, olive oil 4%, propylene glycol 9%, glycerol 6%, high-quality Oleum Ricini 9%, Aloe extract 4%, Rhizoma Zingiberis Recens extract 4.5%, Borneolum Syntheticum 0.63%, eucalyptus oil 0.6%, chrysanthemum esters 0.12%, avilamycin 0.15%, Fipronil 0.2%, Octacide 264 0.6%, terbinafine HCl 2%, ethanol 12%, Camphora extract 1.2%。
Embodiment 3
The anthelmintic spray that a kind of house pet of the present embodiment is unified by multiple-effect, is made up of following raw material by weight ratio: distilled water 35%, olive oil 5%, propylene glycol 8%, glycerol 7%, high-quality Oleum Ricini 15%, Aloe extract 5%, Rhizoma Zingiberis Recens extract 5.5%, Borneolum Syntheticum 0.67%, eucalyptus oil 0.8%, chrysanthemum esters 0.12%, avilamycin 0.15%, Fipronil 0.2%, Octacide 264 0.9%, terbinafine HCl 2%, ethanol 13%, Camphora extract 1.66%。
The preparation method of the anthelmintic spray that a kind of house pet of above example is unified by multiple-effect, comprises the following steps:
(1) chrysanthemum esters, avilamycin, Fipronil, Octacide 264, terbinafine HCl, Borneolum Syntheticum being mixed with ethanol, propylene glycol, high-quality Oleum Ricini, 55-65 DEG C of heating and melting, mix homogeneously forms mixture；
(2) remaining each several part is added in (1) mixture, be eventually adding distilled water。In process always under 55-65 DEG C of water-bath state, namely mix homogeneously obtains medicinal liquid；
(3) medicinal liquid is distributed in watering can, obtains product。

Claims (3)

1. the anthelmintic spray that house pet is unified by multiple-effect, is characterized in being in that to be made up of following raw material by weight ratio: distilled water 40%, olive oil 6%, propylene glycol 12%, glycerol 8%, high-quality Oleum Ricini 10%, Aloe extract 4%, Rhizoma Zingiberis Recens extract 3.4%, Borneolum Syntheticum 0.7%, eucalyptus oil 0.3%, chrysanthemum esters 0.12%, avilamycin 0.25%, Fipronil 0.2%, Octacide 264 0.65%, terbinafine HCl 1%, ethanol 12%, Camphora extract 1.38%。
2. the anthelmintic spray that a kind of house pet is unified by multiple-effect according to claim 1, is characterized in being in that to be made up of the raw material of following optimal proportion by weight: distilled water 46%, olive oil 4%, propylene glycol 9%, glycerol 6%, high-quality Oleum Ricini 9%, Aloe extract 4%, Rhizoma Zingiberis Recens extract 4.5%, Borneolum Syntheticum 0.63%, eucalyptus oil 0.6%, chrysanthemum esters 0.12%, avilamycin 0.15%, Fipronil 0.2%, Octacide 264 0.6%, terbinafine HCl 2%, ethanol 12%, Camphora extract 1.2%。
3. the preparation method of the anthelmintic spray that a kind of house pet described in claim 1 or 2 is unified by multiple-effect, it is characterized in that comprising the following steps: chrysanthemum esters, avilamycin, Fipronil, Octacide 264, terbinafine HCl, Borneolum Syntheticum are mixed by (1) with ethanol, propylene glycol, high-quality Oleum Ricini, 55-65 DEG C of heating and melting, mix homogeneously forms mixture；(2) being added in (1) mixture by remaining each several part, be eventually adding distilled water, in process always under 55-65 DEG C of water-bath state, namely mix homogeneously obtains medicinal liquid；(3) medicinal liquid is distributed in watering can, obtains product。
CN201610163533.0A 2016-03-19 2016-03-19 Pet all-in-one insect expelling spray and preparation method thereof Pending CN105688168A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107996621A (en) * 2017-11-30 2018-05-08 广西南宁益土生物科技有限责任公司 A kind of composition for preventing cockroach
CN108524499A (en) * 2018-07-13 2018-09-14 佛山市南海东方澳龙制药有限公司 The application of the composition of Thymol, Fipronil and terbinafine HCl, animal dermatosis prevent medication and preparation method thereof
CN109453116A (en) * 2017-09-06 2019-03-12 北京中医药大学 A kind of terbinafine HCl spray and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101919852A (en) * 2010-02-08 2010-12-22 华南农业大学 In vitro anti-insect spray for pets and preparation and using methods thereof
CN104288052A (en) * 2014-10-23 2015-01-21 彭尚元 Parasite-expelling conditioner for pets and preparation method thereof
CN105343112A (en) * 2015-09-29 2016-02-24 武汉中博绿亚生物科技有限公司 Fipronil compound preparation for removing ectoparasites of pets and preparing method of fipronil compound preparation
CN105395484A (en) * 2015-12-25 2016-03-16 武汉回盛生物科技有限公司 Compound terbinafine spraying agent and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101919852A (en) * 2010-02-08 2010-12-22 华南农业大学 In vitro anti-insect spray for pets and preparation and using methods thereof
CN104288052A (en) * 2014-10-23 2015-01-21 彭尚元 Parasite-expelling conditioner for pets and preparation method thereof
CN105343112A (en) * 2015-09-29 2016-02-24 武汉中博绿亚生物科技有限公司 Fipronil compound preparation for removing ectoparasites of pets and preparing method of fipronil compound preparation
CN105395484A (en) * 2015-12-25 2016-03-16 武汉回盛生物科技有限公司 Compound terbinafine spraying agent and preparation method thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109453116A (en) * 2017-09-06 2019-03-12 北京中医药大学 A kind of terbinafine HCl spray and preparation method thereof
CN107996621A (en) * 2017-11-30 2018-05-08 广西南宁益土生物科技有限责任公司 A kind of composition for preventing cockroach
CN108524499A (en) * 2018-07-13 2018-09-14 佛山市南海东方澳龙制药有限公司 The application of the composition of Thymol, Fipronil and terbinafine HCl, animal dermatosis prevent medication and preparation method thereof

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