CN105687385A

CN105687385A - Ointment for treating radiodermatitis and preparation

Info

Publication number: CN105687385A
Application number: CN201610116689.3A
Authority: CN
Inventors: 杨莎莎; 王凯
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-02-18
Filing date: 2016-02-18
Publication date: 2016-06-22

Abstract

The invention relates to an ointment for treating radiodermatitis and preparation. The ointment is prepared from, by weight, 0.05%-0.1% of peach kernel oil, 0.01%-0.02% of eucalyptus oil, 0.02%-0.04% of cinnamon oil, 0.02%-0.04% of oleum ocimi gratissimi, 0.01%-0.04% of oleum menthae and 5%-10% of olive oil. The ointment for treating the radiodermatitis has the advantages of being capable of improving radiation resistance of skin, improving partial circulation, nourishing the skin, dispelling wind, relieving pain and promoting repair of skin mucous membranes, good in curative effect, capable of giving comfort to a patient and free of toxic and side effects.

Description

The unguentum of a kind for the treatment of radiation dermatitis and preparation

Technical field

The present invention relates to the unguentum of a kind for the treatment of radiation dermatitis and preparation。

Background technology

It is known that radiodermatitis kinds of tumor Patients Treated by Radiotherapy or be occupational employee exposed to radiation or accept the patient of radiation treatment。By the skin injury that ionizing radiation causes。All claiming radiodermatitis, clinical manifestation: I degree is xerosis cutis, pigmentation or depigmentation, coarse, fingernail is gloomy or vertical ridge vitta first；II degree is hyperkeratosis, chap or atrophy is thinning, telangiectasis, and fingernail thickens deformation etc.；III degree is downright bad ulcer, cutin projection, the fusion of finger tip keratinization, tendon contracture, joint deformity, dysfunction etc.。Being subject to Chronic radiation damage, skin can occur flat or excipuliform to have matter hypertrophy, or forms intractable ulcer, can secondary basal cell carcinoma or scale cancer。Treatment at present does not have active drug, simply symptomatic treatment。

Summary of the invention

The invention aims to solve above-mentioned technical deficiency, it is provided that this medicine absorbance height, few side effects, cure rate height, cost is low and the unguentum of a kind for the treatment of radiation dermatitis that has no side effect and preparation。

The medicine have the advantages that have raising skin capability of resistance to radiation, improve local circulation, nourishes rough skin, wind-expelling pain-stopping, promote skin mucosa reparation。Good effect, to patient comfort, has no side effect。

For achieving the above object, the unguentum of a kind for the treatment of radiation dermatitis, it is characterised in that the percentage by weight of crude drug extract is as follows:

Peach kernel oil 0.05～0.1%, Oleum Eucalypti 0.01～0.02%, Oleum Cinnamomi 0.02～0.04%, Oleum Ocimi Gratissimi 0.02～0.04%, Oleum menthae 0.01～0.04%, olive oil 5～10%。

Preparation method: Semen Juglandis is first fried micro-Huang, extruder frying oil merges slow fire heating with above-mentioned volatile oil, refluxes 10 minutes, lets cool, and filters, standby。Add dextrin by 1: 1, be concentrated into the clear paste that relative density is 1.15～1.25 (60 DEG C)。Obtain。

The Semen Juglandis that peach kernel oil in Chinese medicine of the present invention comes, its external can protect skin, plays softening and nourishes, and it plays antipruritic after being absorbed lentamente；Damp eliminating rash effect。Oleum Eucalypti containing eucalyptol (C10H18O) function with cure mainly: wind-expelling pain-stopping。For skin pruritus, neuralgia。Oleum Cinnamomi this product is the volatile oil that the dry branch of canella Cortex Cinnamomi CinnamomumcassiaPresl, leaf obtain through steam distillation。Function with cure mainly: wind dispelling, stomach invigorating。Olive oil has blood circulation promoting, and the effect of skin is repaired in nutrition。Oleum Ocimi Gratissimi this product containing eugenol (C10H12O2) function with cure mainly: analgesia, anticorrosion。For fresh stem that the Oleum menthae this product such as dental caries are labiate Herba Menthae MenthahaplocalyxBriq. and Ye Jing vapor distillation, more freezing, the de-brain of part processes the volatile oil obtained。Can be used for skin or mucosa produces refrigerant sense to alleviate discomfort and pain。Above compatibility of drugs, brings out the best in each other。

The present invention follows the prescriptions principle of the traditional Chinese medical science, the present invention according to clinical verification: effective percentage is more than 90%, and cure rate is more than 80%, has no side effect。

Detailed description of the invention

Below in conjunction with implementing case, the invention will be further described:

Embodiment 1: the unguentum of a kind for the treatment of radiation dermatitis and preparation, it is characterised in that the percentage by weight of various volatile oil is as follows:

Peach kernel oil 0.05～0.1%, Oleum Eucalypti 0.01～0.02%, Oleum Cinnamomi 0.02～0.04%, Oleum Ocimi Gratissimi 0.02～0.04%, Oleum menthae 0.01～0.04%, olive oil 5～10%。Preparation technology ibid, obtains runny plaste。

Embodiment 2: unguentum and preparation, by peach kernel oil 0.1%, Oleum Eucalypti 0.02%, Oleum Cinnamomi 0.02%, Oleum Ocimi Gratissimi 0.04%, Oleum menthae 0.02%, olive oil 10%。Preparation technology, with embodiment 1, obtains unguentum 100g。

Clinical efficacy is summed up:

One, we are extensive in clinical practice for many years, treat example patient up to a hundred, and curative effect frequency is good。Use and note: anemia of pregnant woman, menorrhagia person avoid use。

Two, diagnosis basis: have radiation history, clinical manifestation: I degree is xerosis cutis, pigmentation or depigmentation, coarse, fingernail is gloomy or vertical ridge vitta first；II degree is hyperkeratosis, chap or atrophy is thinning, telangiectasis, and fingernail thickens deformation etc.；III degree is downright bad ulcer, cutin projection, the fusion of finger tip keratinization, tendon contracture, joint deformity, dysfunction etc.。Being subject to chronic radioactive damage, skin can occur flat or excipuliform to have matter hypertrophy, or forms intractable ulcer, can secondary basal cell carcinoma or scale cancer。

Three, administrated method: 10g every time, morning every day, external application affected part, 10th be 1 course for the treatment of。

Four, efficacy evaluation:

Cure: clinical symptoms is wholly absent。

Take a turn for the better: clinical symptom relief。

Do not heal: sings and symptoms is not improved。

Five, therapeutic effect: treatment by Chinese herbs primary disease of the present invention, through statistics cure rate more than 85%, effective percentage more than 90%。

Six, model case:

1. Lee XX, female, 30 years old。In August, 2012 goes to a doctor。Main suit's row radical mastectomy, radiotherapy occurs after 2 weeks that axillary fossa mucosa is rubescent, edema；Rotten to the corn。Effect is loseed through anti-inflammatory ointment。Through patient requests with 1 course for the treatment of of Chinese medicinal ointment of the present invention, clinical symptoms is wholly absent, and follows up a case by regular visits to and do not recur again after half a year。

2. king XX, female, 35 years old。In November, 2014 goes to a doctor。Main suit's row operation of lung cancer, radiotherapy occurs after 3 weeks that left chest mucosa is rubescent, edema；Rotten to the corn。Effect is loseed through anti-inflammatory ointment。Through patient requests with 1 course for the treatment of of Chinese medicinal ointment of the present invention, clinical symptoms is wholly absent, and follows up a case by regular visits to and do not recur again after half a year。

3. Lee XX, man, 42 years old。In January, 2015 goes to a doctor。Main suit's skull tumors postoperation radiotherapy 1 month。Scalp mucosa is rubescent, edema, and color is dark gradually。Patient requests is with 3 courses for the treatment of of Chinese medicinal ointment of the present invention, and clinical symptoms is wholly absent, and follows up a case by regular visits to and do not recur again after half a year。

Claims

1. the unguentum of a treating radiation dermatitis, it is characterised in that the percentage by weight of various volatile oil is as follows: peach kernel oil 0.05～0.1%, Oleum Eucalypti 0.01～0.02%, Oleum Cinnamomi 0.02～0.04%, Oleum Ocimi Gratissimi 0.02～0.04%, Oleum menthae 0.01～0.04%, olive oil 5～10%。

2. the preparation method according to the unguentum of claim 1 treating radiation dermatitis, it is characterised in that Semen Juglandis is first fried micro-Huang, extruder frying oil merges slow fire heating with above-mentioned volatile oil, refluxes 10 minutes, lets cool, and filters, standby。Add dextrin by 1: 1, be concentrated into the clear paste that relative density is 1.15～1.25 (60 DEG C)。Obtain。