CN105683152B - 用于治疗高血压和/或纤维化的组合物 - Google Patents
用于治疗高血压和/或纤维化的组合物 Download PDFInfo
- Publication number
- CN105683152B CN105683152B CN201480050979.1A CN201480050979A CN105683152B CN 105683152 B CN105683152 B CN 105683152B CN 201480050979 A CN201480050979 A CN 201480050979A CN 105683152 B CN105683152 B CN 105683152B
- Authority
- CN
- China
- Prior art keywords
- fibrosis
- treatment
- pharmaceutically acceptable
- hypertension
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013903573 | 2013-09-17 | ||
| AU2013903573A AU2013903573A0 (en) | 2013-09-17 | Compositions for the treatment of hypertension and/or fibrosis | |
| PCT/AU2014/000923 WO2015039173A1 (en) | 2013-09-17 | 2014-09-17 | Compositions for the treatment of hypertension and/or fibrosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105683152A CN105683152A (zh) | 2016-06-15 |
| CN105683152B true CN105683152B (zh) | 2017-03-22 |
Family
ID=52687998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480050979.1A Active CN105683152B (zh) | 2013-09-17 | 2014-09-17 | 用于治疗高血压和/或纤维化的组合物 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9458093B2 (https=) |
| EP (1) | EP3046901B1 (https=) |
| JP (1) | JP6122548B2 (https=) |
| KR (1) | KR101736416B1 (https=) |
| CN (1) | CN105683152B (https=) |
| AP (1) | AP2016009079A0 (https=) |
| AU (1) | AU2014324078B2 (https=) |
| BR (1) | BR112016005601B1 (https=) |
| CA (1) | CA2924356C (https=) |
| DK (1) | DK3046901T3 (https=) |
| ES (1) | ES2655455T3 (https=) |
| IL (1) | IL244621A (https=) |
| MX (1) | MX368865B (https=) |
| MY (1) | MY172557A (https=) |
| NO (1) | NO3046901T3 (https=) |
| NZ (1) | NZ717927A (https=) |
| PH (1) | PH12016500497B1 (https=) |
| PL (1) | PL3046901T3 (https=) |
| RU (1) | RU2635564C2 (https=) |
| SG (1) | SG11201601642WA (https=) |
| UA (1) | UA118111C2 (https=) |
| WO (1) | WO2015039173A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3284981B2 (ja) | 1998-11-02 | 2002-05-27 | 株式会社デンソー | 車両用交流発電機およびそのステータの製造方法 |
| US9956166B2 (en) | 2013-09-18 | 2018-05-01 | Sorrento Therapeutics, Inc. | Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin |
| MX376504B (es) | 2015-03-18 | 2025-03-07 | Vectus Biosystems Ltd | Composiciones para el tratamiento de enfermedades renales y/o hepaticas. |
| DK3271320T3 (da) * | 2015-03-18 | 2020-02-03 | Vectus Biosystems Ltd | Sammensætninger til behandling af fibrose og fibroserelaterede tilstande |
| EP3353147B1 (en) * | 2015-09-22 | 2021-01-13 | Vectus Biosystems Limited | Synthesis of terphenyl compounds |
| IL298314B2 (en) * | 2016-04-13 | 2025-04-01 | Univ Nebraska | Methods of administration and methods of treating cardiovascular diseases with resiniparatoxin |
| BR112019001510B1 (pt) * | 2016-07-28 | 2022-11-08 | Vectus Biosystems Limited | Composto, e, uso de um composto para manufatura de um medicamento para tratar profilática ou terapeuticamente fibrose pulmonar, ou uma enfermidade relacionada em um indivíduo com fibrose pulmonar ou em risco de desenvolver fibrose pulmonar |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1993137A (zh) * | 2004-06-11 | 2007-07-04 | 维克特斯生物系统有限公司 | 用于治疗心血管疾病的组合物和方法 |
| US20110082109A1 (en) * | 2009-10-02 | 2011-04-07 | Ajinomoto Co., Inc. | Novel acyl guanidine derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2694288B1 (fr) * | 1992-06-30 | 1994-09-09 | Rhone Poulenc Agrochimie | Phenylbenzamides fongicides et procédés pour les préparer. |
| NZ623674A (en) * | 2005-12-09 | 2014-07-25 | Vectus Biosystems Ltd | Vip fragments and methods of use |
| JP6293266B2 (ja) * | 2013-09-17 | 2018-03-14 | ヴェクタス バイオシステムズ リミテッド | 高血圧及び／又は線維症の処置用組成物 |
-
2014
- 2014-09-17 NO NO14845373A patent/NO3046901T3/no unknown
- 2014-09-17 ES ES14845373.1T patent/ES2655455T3/es active Active
- 2014-09-17 SG SG11201601642WA patent/SG11201601642WA/en unknown
- 2014-09-17 AP AP2016009079A patent/AP2016009079A0/xx unknown
- 2014-09-17 KR KR1020167008664A patent/KR101736416B1/ko active Active
- 2014-09-17 US US15/022,278 patent/US9458093B2/en active Active
- 2014-09-17 RU RU2016112257A patent/RU2635564C2/ru active
- 2014-09-17 DK DK14845373.1T patent/DK3046901T3/en active
- 2014-09-17 CA CA2924356A patent/CA2924356C/en active Active
- 2014-09-17 AU AU2014324078A patent/AU2014324078B2/en active Active
- 2014-09-17 EP EP14845373.1A patent/EP3046901B1/en active Active
- 2014-09-17 UA UAA201602267A patent/UA118111C2/uk unknown
- 2014-09-17 WO PCT/AU2014/000923 patent/WO2015039173A1/en not_active Ceased
- 2014-09-17 PL PL14845373T patent/PL3046901T3/pl unknown
- 2014-09-17 MY MYPI2016000482A patent/MY172557A/en unknown
- 2014-09-17 NZ NZ717927A patent/NZ717927A/en unknown
- 2014-09-17 CN CN201480050979.1A patent/CN105683152B/zh active Active
- 2014-09-17 JP JP2016515425A patent/JP6122548B2/ja active Active
- 2014-09-17 MX MX2016003371A patent/MX368865B/es active IP Right Grant
- 2014-09-17 BR BR112016005601-9A patent/BR112016005601B1/pt active IP Right Grant
-
2016
- 2016-03-14 PH PH12016500497A patent/PH12016500497B1/en unknown
- 2016-03-16 IL IL244621A patent/IL244621A/en active IP Right Grant
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1993137A (zh) * | 2004-06-11 | 2007-07-04 | 维克特斯生物系统有限公司 | 用于治疗心血管疾病的组合物和方法 |
| US20110082109A1 (en) * | 2009-10-02 | 2011-04-07 | Ajinomoto Co., Inc. | Novel acyl guanidine derivatives |
Non-Patent Citations (1)
| Title |
|---|
| A modular synthesis of teraryl-based a-helix mimetics, part 1:synthesis of core fragments with two electronically differentiated leaving groups;Martin Peters et al;《Chem.Eur.J.》;20130104;第19卷;2442-2449 * |
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|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |