CN105641613A - 一种治疗心绞痛的中药 - Google Patents
一种治疗心绞痛的中药 Download PDFInfo
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Abstract
本发明涉及中药应用领域，特别公开了一种治疗心绞痛的中药。该治疗心绞痛的中药，以娑罗子、檀香、沉香、毛冬青、附子、红花、三棱、莪术，炒白芍和炙甘草为原料，按照一定的重量配比混合制成。本发明制备简单，疗效显著，吸收效果好，药效持续时间长，无毒副作用，安全性高，生产成本低，有利于病患及时减轻病状，适于广泛推广应用。
Description
（一）技术领域
本发明涉及中药应用领域，特别涉及一种治疗心绞痛的中药。
（二）背景技术
冠心病心绞痛是由于冠状动脉粥样硬化导致管腔狭窄或冠状动脉痉挛，使心肌缺血和缺氧而引起的胸部发作性疼痛或不适，是冠心病中的一个常见类型。近几年来，冠心病心绞痛的发病率明显升高，在心脏病中的比例已跃居首位。
冠心病心绞痛属中医学“胸痹”、“心痛”范畴，其病机为心阳不足、气滞血瘀、心脉瘀阻，为本虚标实之证。中医认为本病的发生于年老体虚、肾气不足、膏粱厚味、脾胃损伤、七情内伤、气滞血瘀、思考劳倦、伤及心脾等因素有关，同时指出在本病的发病过程中，心、脾、肾虚是病之本，而气滞、血瘀、痰浊、痹阻是病之标。临床多为正虚邪实、虚实相兼出现。冠心病心绞痛的治疗应按虚实加以辩证论治，采用辩证与辨病相结合的方法，长采用“补”与“通”两大法则。
现有各种治疗心绞痛的中西药品，疗效并不理想，易产生不良反应，易引发副作用等作用，现有类似药品，品种单一，疗效也不稳定，病情较轻还有效，病情加重就无效了。
（三）发明内容
本发明为了弥补现有技术的不足，提供了一种制备简单、疗效显著的治疗心绞痛的中药。
本发明是通过如下技术方案实现的：
一种治疗心绞痛的中药，由以下重量份数的原料制成：
娑罗子10-15份、檀香5-10份、沉香2-5份、毛冬青30-50份、附子10-15份、红花10-15份、三棱10-15份、莪术10-15份，炒白芍20-30份、炙甘草5-10份。
其优选的各原料的重量配比为：
娑罗子12份、檀香8份、沉香3份、毛冬青40份、附子12份、红花12份、三棱12份、莪术12份，炒白芍25份、炙甘草8份。
所述原料加十倍重量的水浸泡2小时，之后大火煎煮三次，第一次煎煮1小时，第二次和第三次分别煎煮40min，合并三次煎煮药液，浓缩至膏状后，加入糊精、白砂糖混合均匀，用40目规格的筛网制成颗粒，晾晒或烘干后得到产品。
所述中药膏、糊精和白砂糖的重量比为1:1:1.5。
心绞痛是冠心病的一种病症，本发明既能治疗冠心病，又能治疗心绞痛，而且特别加重了娑罗子、檀香的用量，取得了意想不到的止痛效果。
各原料的药性分析如下：
娑罗子：归肝胃经，理气宽中，和胃止痛，主治心痛、胃痛；
檀香：辛温，归脾胃、心肺经，理气温中，开胃止痛，主治胃痛、腹痛、冠心病、心绞痛；
沉香：辛苦微温，归脾胃肾经，行气止痛，主治心腹作痛，气逆喘急；
毛冬青：苦涩寒，活血，凉血，通脉，消炎等，主治血栓性脉管炎、冠状动脉硬化性心脏病；
红花：辛温，归心肝经，破气行血，消积止痛，主治血瘀经闭，腹痛，癥瘕痞块等；
三棱：辛苦平，归肝经，破气行血，消积止痛，主治血瘀经闭，腹痛，癥瘕痞块等；
莪术：辛苦温，归肝脾经，行气破血，消积止痛，主治同三棱；
附子：辛甘，大热，有毒，归脾肾经，回阳救逆，祛风寒湿邪，主治脉微欲绝，阳气不足，命门火衰等；
白芍：苦酸，微寒，归肝脾经，平肝止痛，养血调经，止汗，主治柔肝止痛，养血敛阴，头痛，肋痛等；
炙甘草：甘平，补脾益气，调和诸药，润肺止咳。
配方中，君药为娑罗子、檀香和沉香，用于行气止痛；臣药为毛冬青和红花，用于祛瘀活血，散瘀止痛；佐药为三棱和莪术，用于行气破血，消积止痛；使药为附子、炒白芍和炙甘草，用于温中回阳，调和诸药，缓急止痛。
临床观察：
（1）临床资料
本发明人于2007年至今，对485例心绞痛患者进行临床观察治疗，年龄24-80岁。
（2）治疗方法
口服，一日三次，每次10-15g，饭后服用。根据患者病情轻重计算治疗时间，轻度患者服用10-15天左右，重病患者连服90-120天即可痊愈。
（3）疗效判定标准
疗效标准参照《中医病症判断疗效标准》中有关疗效标准。
治愈：临床症状全部消失，实验室检查正常。
显效：临床症状基本消失，试验室检查各相关指标接近正常水平。
有效：临床症状减轻，试验室检查各相关指标有所改善，体征有改善。
无效：临床症状无明显好转或加重。
（4）临床结果
临床治愈411例（84.74%），显效44例（9.07%），有效16例（3.30%），无效14例（2.89%），总有效率为97.11%。
典型病例：
（1）甘某某：女，79岁，2015年6月12日来诊，患冠心病心绞痛已十几年，经过各种治疗，疗效不佳，听朋友介绍来诊，服用本发明中药，七天止痛，三个月痊愈；
（2）徐某某：男，27岁，2015年6月23日来诊，胸闷气短已数年，来诊前几天心绞痛严重，服用本发明中药5天疼痛减轻，两个月痊愈；
（3）赵某某：男，34岁，2015年7月20日来诊，胸闷气短，心绞痛，服用本发明中药七天止痛，巩固治疗两个月痊愈；
（4）樊某某：男，43岁，2015年7月28日来诊，胸闷气短，心绞痛已数年，来诊前几天痛感加重，服药本发明中药5天疼痛减轻，两个月痊愈；
（5）刘某某：男，56岁，2015年9月13日来诊，胸闷气短，心绞痛，服用本发明中药七天止痛，两个月痊愈；
（6）郭某：女，42岁，2015年9月26日来诊，胸闷气短，心绞痛，乏力，服用本发明中药七天止痛，巩固治疗两个月痊愈。
本发明制备简单，疗效显著，吸收效果好，药效持续时间长，无毒副作用，安全性高，生产成本低，有利于病患及时减轻病状，适于广泛推广应用。
（四）具体实施方式
实施例1：
取娑罗子10g、檀香5g、沉香2g、毛冬青30g、附子10g、红花10g、三棱10g、莪术10g，炒白芍20g、炙甘草5g，将上述原料混合后加十倍重量的水浸泡2小时，之后大火煎煮三次，第一次煎煮1小时，第二次和第三次分别煎煮40min，合并三次煎煮药液，浓缩至膏状后，加入糊精、白砂糖混合均匀，用40目规格的筛网制成颗粒，晾晒或烘干后得到产品，其中，中药膏、糊精和白砂糖的重量比为1:1:1.5。
用法用量：口服，一日三次，每次10-15g，饭后服用。
实施例2：
取娑罗子15g、檀香10g、沉香5g、毛冬青50g、附子15g、红花15g、三棱15g、莪术15g，炒白芍30g、炙甘草10g，将上述原料混合后加十倍重量的水浸泡2小时，之后大火煎煮三次，第一次煎煮1小时，第二次和第三次分别煎煮40min，合并三次煎煮药液，浓缩至膏状后，加入糊精、白砂糖混合均匀，用40目规格的筛网制成颗粒，晾晒或烘干后得到产品，其中，中药膏、糊精和白砂糖的重量比为1:1:1.5。
用法用量：口服，一日三次，每次10-15g，饭后服用。
实施例3：
取娑罗子12g、檀香8g、沉香3g、毛冬青40g、附子12g、红花12g、三棱12g、莪术12g，炒白芍25g、炙甘草8g，将上述原料混合后加十倍重量的水浸泡2小时，之后大火煎煮三次，第一次煎煮1小时，第二次和第三次分别煎煮40min，合并三次煎煮药液，浓缩至膏状后，加入糊精、白砂糖混合均匀，用40目规格的筛网制成颗粒，晾晒或烘干后得到产品，其中，中药膏、糊精和白砂糖的重量比为1:1:1.5。
用法用量：口服，一日三次，每次10-15g，饭后服用。
Claims (4)
1.一种治疗心绞痛的中药，其特征为，由以下重量份数的原料制成：娑罗子10-15份、檀香5-10份、沉香2-5份、毛冬青30-50份、附子10-15份、红花10-15份、三棱10-15份、莪术10-15份，炒白芍20-30份、炙甘草5-10份。
2.根据权利要求1所述的治疗心绞痛的中药，其特征为，由以下重量分数的原料制成：娑罗子12份、檀香8份、沉香3份、毛冬青40份、附子12份、红花12份、三棱12份、莪术12份，炒白芍25份、炙甘草8份。
3.根据权利要求1或2所述的治疗心绞痛的中药，其特征在于：所述原料加十倍重量的水浸泡2小时，之后大火煎煮三次，第一次煎煮1小时，第二次和第三次分别煎煮40min，合并三次煎煮药液，浓缩至膏状后，加入糊精、白砂糖混合均匀，用40目规格的筛网制成颗粒，晾晒或烘干后得到产品。
4.根据权利要求3所述的治疗心绞痛的中药，其特征在于：所述中药膏、糊精和白砂糖的重量比为1:1:1.5。
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