CN1056369C - 哒嗪酮衍生物或其盐和制备方法 - Google Patents

哒嗪酮衍生物或其盐和制备方法 Download PDF

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Publication number
CN1056369C
CN1056369C CN94193266A CN94193266A CN1056369C CN 1056369 C CN1056369 C CN 1056369C CN 94193266 A CN94193266 A CN 94193266A CN 94193266 A CN94193266 A CN 94193266A CN 1056369 C CN1056369 C CN 1056369C
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China
Prior art keywords
alkyl
group
hydrogen atom
compound
general formula
Prior art date
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Expired - Fee Related
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CN94193266A
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English (en)
Chinese (zh)
Other versions
CN1130378A (zh
Inventor
重原格
小田原新二
冈田宏
木村博彦
尾松正人
中山仁志
樋口理惠
武南多纪
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Ishihara Sangyo Kaisha Ltd
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Ishihara Sangyo Kaisha Ltd
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Publication of CN1130378A publication Critical patent/CN1130378A/zh
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Publication of CN1056369C publication Critical patent/CN1056369C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN94193266A 1993-09-06 1994-08-22 哒嗪酮衍生物或其盐和制备方法 Expired - Fee Related CN1056369C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP246344/1993 1993-09-06
JP246344/93 1993-09-06
JP24634493 1993-09-06
JP87999/94 1994-04-01
JP87999/1994 1994-04-01
JP8799994 1994-04-01

Publications (2)

Publication Number Publication Date
CN1130378A CN1130378A (zh) 1996-09-04
CN1056369C true CN1056369C (zh) 2000-09-13

Family

ID=26429218

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94193266A Expired - Fee Related CN1056369C (zh) 1993-09-06 1994-08-22 哒嗪酮衍生物或其盐和制备方法

Country Status (12)

Country Link
US (1) US5763439A (enExample)
EP (1) EP0717734B1 (enExample)
KR (1) KR960704853A (enExample)
CN (1) CN1056369C (enExample)
AT (1) ATE173471T1 (enExample)
AU (1) AU681694B2 (enExample)
CA (1) CA2170637C (enExample)
DE (1) DE69414716T2 (enExample)
ES (1) ES2125474T3 (enExample)
IL (1) IL110845A (enExample)
TW (1) TW259787B (enExample)
WO (1) WO1995007264A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2147841T3 (es) * 1994-01-25 2000-10-01 Nissan Chemical Ind Ltd Derivados de piridazinona.
KR100657189B1 (ko) 1998-08-14 2006-12-14 니혼노야쿠가부시키가이샤 피리다지논 유도체 및 이를 함유하는 의약 조성물
JP4711520B2 (ja) * 2000-03-21 2011-06-29 日本ケミカルリサーチ株式会社 生理活性ペプチド含有粉末
CN102532126B (zh) * 2012-02-10 2014-06-18 贵州大学 2-取代-4-氯-5-[5-取代胺基-2-(1,3,4-噻二唑基)-巯基]-3(2h)-哒嗪酮类衍生物及其制备方法和用途
CN104230902B (zh) * 2013-06-19 2017-05-10 中国科学院大连化学物理研究所 一类6,7‑二羟基香豆素衍生物、制备方法和应用
WO2020169042A1 (zh) * 2019-02-20 2020-08-27 江苏恒瑞医药股份有限公司 6-氧代-1,6-二氢哒嗪类前药衍生物、其制备方法及其在医药上的应用
WO2023166067A1 (en) 2022-03-02 2023-09-07 Syngenta Crop Protection Ag Microbiocidal pyridazinone amide derivatives
WO2024132895A1 (en) 2022-12-19 2024-06-27 Syngenta Crop Protection Ag Microbiocidal dihydrooxadiazinyl pyridazinone compounds
EP4638425A1 (en) 2022-12-19 2025-10-29 Syngenta Crop Protection AG Microbiocidal pyridazine dihydrooxadiazine derivatives

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0186817A1 (en) * 1984-12-10 1986-07-09 Nissan Chemical Industries Ltd. 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it
EP0275997A1 (en) * 1987-01-20 1988-07-27 Nissan Chemical Industries Ltd. 3(2H)pyridazinone, process for its preparation and antagonistic agent against SRS-A containing it
EP0376079A1 (en) * 1988-12-20 1990-07-04 Nissan Chemical Industries Ltd. 3(2H)pyridazinones, processes for their preparation and antagonistic agent against SRS-A
WO1990013292A1 (en) * 1989-04-28 1990-11-15 Brigham And Women's Hospital Use of lipoxin a4 and its derivatives as antagonists for slow-reacting substances of anaphylaxis
EP0482208A1 (en) * 1990-04-25 1992-04-29 Nissan Chemical Industries Ltd. Pyridazinone derivative

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0186817A1 (en) * 1984-12-10 1986-07-09 Nissan Chemical Industries Ltd. 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it
EP0275997A1 (en) * 1987-01-20 1988-07-27 Nissan Chemical Industries Ltd. 3(2H)pyridazinone, process for its preparation and antagonistic agent against SRS-A containing it
EP0376079A1 (en) * 1988-12-20 1990-07-04 Nissan Chemical Industries Ltd. 3(2H)pyridazinones, processes for their preparation and antagonistic agent against SRS-A
WO1990013292A1 (en) * 1989-04-28 1990-11-15 Brigham And Women's Hospital Use of lipoxin a4 and its derivatives as antagonists for slow-reacting substances of anaphylaxis
EP0482208A1 (en) * 1990-04-25 1992-04-29 Nissan Chemical Industries Ltd. Pyridazinone derivative

Also Published As

Publication number Publication date
TW259787B (enExample) 1995-10-11
IL110845A0 (en) 1994-11-28
WO1995007264A1 (en) 1995-03-16
EP0717734A1 (en) 1996-06-26
ES2125474T3 (es) 1999-03-01
AU681694B2 (en) 1997-09-04
ATE173471T1 (de) 1998-12-15
DE69414716T2 (de) 1999-04-08
CA2170637C (en) 2005-01-25
IL110845A (en) 1999-01-26
CN1130378A (zh) 1996-09-04
DE69414716D1 (de) 1998-12-24
EP0717734B1 (en) 1998-11-18
AU7467694A (en) 1995-03-27
KR960704853A (ko) 1996-10-09
CA2170637A1 (en) 1995-03-16
US5763439A (en) 1998-06-09

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