CN105636985A - 用于治疗癌症和病毒感染的免疫受体调节 - Google Patents

用于治疗癌症和病毒感染的免疫受体调节 Download PDF

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CN105636985A
CN105636985A CN201480052069.7A CN201480052069A CN105636985A CN 105636985 A CN105636985 A CN 105636985A CN 201480052069 A CN201480052069 A CN 201480052069A CN 105636985 A CN105636985 A CN 105636985A
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cells
domain
mammal
inhibitory agent
human
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M·斯迈思
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QIMR Berghofer Medical Research Institute
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Queensland Institute of Medical Research QIMR
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Priority claimed from AU2013903189A external-priority patent/AU2013903189A0/en
Priority claimed from PCT/AU2013/001132 external-priority patent/WO2015024042A1/en
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Publication of CN105636985A publication Critical patent/CN105636985A/zh
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    • C07ORGANIC CHEMISTRY
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01K67/0276Knock-out vertebrates
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    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P37/00Drugs for immunological or allergic disorders
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    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0331Animal model for proliferative diseases
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01K2267/0387Animal model for diseases of the immune system
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    • A61K2039/507Comprising a combination of two or more separate antibodies
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    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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CN201480052069.7A 2013-08-22 2014-08-22 用于治疗癌症和病毒感染的免疫受体调节 Pending CN105636985A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
AU2013903189 2013-08-22
AU2013903189A AU2013903189A0 (en) 2013-08-22 Immunomodulator
AUPCT/AU2013/001132 2013-10-03
PCT/AU2013/001132 WO2015024042A1 (en) 2013-08-22 2013-10-03 Immunoreceptor modulation for treating cancer and viral infections
AU2014900741A AU2014900741A0 (en) 2014-03-05 Immunoreceptor modulation for treating cancer and viral infections
AU2014900741 2014-03-05
AU2014901002 2014-03-21
AU2014901002A AU2014901002A0 (en) 2014-03-21 Immunoreceptor modulation for treating cancer and viral infections
PCT/AU2014/000830 WO2015024060A1 (en) 2013-08-22 2014-08-22 Immunoreceptor modulation for treating cancer and viral infections

Publications (1)

Publication Number Publication Date
CN105636985A true CN105636985A (zh) 2016-06-01

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US (2) US20160208000A1 (enExample)
EP (1) EP3036258B1 (enExample)
JP (4) JP6618908B2 (enExample)
KR (3) KR20250024106A (enExample)
CN (1) CN105636985A (enExample)
BR (1) BR112016003532A8 (enExample)
CA (1) CA2921774C (enExample)
DK (1) DK3036258T3 (enExample)
ES (1) ES2967538T3 (enExample)
FI (1) FI3036258T3 (enExample)
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HU (1) HUE063307T2 (enExample)
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NZ (1) NZ717534A (enExample)
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SG (1) SG11201601283PA (enExample)
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CN116064400A (zh) * 2015-07-29 2023-05-05 昂克医疗有限公司 具有增强的细胞毒性的修饰的天然杀伤细胞和天然杀伤细胞系

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116064400A (zh) * 2015-07-29 2023-05-05 昂克医疗有限公司 具有增强的细胞毒性的修饰的天然杀伤细胞和天然杀伤细胞系
CN116064400B (zh) * 2015-07-29 2025-09-16 昂克医疗有限公司 具有增强的细胞毒性的修饰的天然杀伤细胞和天然杀伤细胞系
WO2019091449A1 (zh) 2017-11-10 2019-05-16 江苏恒瑞医药股份有限公司 Cd96抗体、其抗原结合片段及医药用途
CN110914304A (zh) * 2017-11-10 2020-03-24 江苏恒瑞医药股份有限公司 Cd96抗体、其抗原结合片段及医药用途
TWI758558B (zh) * 2017-11-10 2022-03-21 大陸商江蘇恒瑞醫藥股份有限公司 Cd96抗體、其抗原結合片段及醫藥用途
CN110914304B (zh) * 2017-11-10 2022-07-26 江苏恒瑞医药股份有限公司 Cd96抗体、其抗原结合片段及医药用途

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JP6618908B2 (ja) 2019-12-11
CA2921774A1 (en) 2015-02-26
MY192043A (en) 2022-07-24
BR112016003532A8 (pt) 2018-01-30
HK1225396A1 (zh) 2017-09-08
KR20250024106A (ko) 2025-02-18
US20210047403A1 (en) 2021-02-18
HUE063307T2 (hu) 2024-01-28
JP2023156487A (ja) 2023-10-24
DK3036258T3 (da) 2023-10-09
KR20160055819A (ko) 2016-05-18
EP3036258B1 (en) 2023-07-19
PL3036258T3 (pl) 2023-12-11
JP2020059714A (ja) 2020-04-16
EP3036258A4 (en) 2017-03-29
US20160208000A1 (en) 2016-07-21
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JP2016530268A (ja) 2016-09-29
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MX2016002263A (es) 2016-12-16
SI3036258T1 (sl) 2023-11-30
ES2967538T3 (es) 2024-04-30
NZ717534A (en) 2022-04-29
KR20230085220A (ko) 2023-06-13
JP2022044808A (ja) 2022-03-17

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