CN105617264A - Traditional Chinese medicine composition preparation for treating uterus cancer and preparation process thereof - Google Patents
Traditional Chinese medicine composition preparation for treating uterus cancer and preparation process thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition preparation for treating uterus cancer. The traditional Chinese medicine composition preparation is mainly prepared from, by weight, 3-10 parts of gecko, 4-10 parts of raw manis pentadactyla scale, 1-5 parts of manis pentadactyla blood, 1-3 parts of java brucea, 1-3 parts of radix sophorae tonkinensis, 5-15 parts of moringa oleifera, 5-16 parts of acai berry, 5-15 parts of gynura divaricata, 10-30 parts of notoginseng bud, 8-25 parts of rhizoma chuanxiong, 6-15 parts of angelica sinensis, 2-8 parts of rhizoma curcumae, 2-8 parts of resina draconis, 1-5 parts of radix gentianae, 5-15 parts of dendrobium, 2-6 parts of cordyceps sinensis, 2-6 parts of American ginseng, 4-10 parts of radix clematidis, 6-13 parts of Tupidanthus calyptratus and 2-6 parts of radix curcuma. The traditional Chinese medicine composition preparation is preferably prepared into capsules. The traditional Chinese medicine composition preparation has the advantage that the traditional Chinese medicine materials are reasonably combined to achieve effects of strengthening and consolidating body resistance, promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain, blocking cancer cells and increasing body immunity so as to finally cure the uterus cancer.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly a kind of Chinese medicinal composition preparation treating uterus carcinoma and production technology thereof.
Background technology
Uterus carcinoma is one of modal malignant tumor of gynecological, and uterus carcinoma includes carcinoma of corpus uteri (also known as carcinoma of endometrium) and cervical cancer. In the world, there are about more than 20 ten thousand women every year and die from cervical cancer, in developing country, cervical cancer then belongs to common multiple gynecological tumor, ranks the umber one. Uterus carcinoma refers to and the malignant tumor at utero vaginal portion and cervical canal occurs, and the transfer of cervical cancer can to adjacent tissue and organ direct extension, down to fornix vaginae and vaginal wall, upwards can invade body of uterus, pelvic tissue can be invaded to both sides, bladder can be invaded forward, rectum can be invaded backward.
It is intended to the Chinese medicine for the treatment of uterus tumor at present, is primarily present the deficiency of several aspect: one is that drug effect is not notable; Two is that the comparison that takes effect is slow; Three is can not treating both the principal and secondary aspects of a disease. A lot of uterus carcinoma patients can not effectively control the growth of tumor, transfer and diffusion because of medicine, or does not recur again after drug administration, thus have impact on the time of existence.
Summary of the invention
The invention provides a kind of Chinese medicinal composition preparation treating uterus carcinoma and production technology thereof, uterus carcinoma is had significant therapeutic effect by prepared Chinese medicinal composition preparation.
For achieving the above object, the technical scheme is that
A kind of Chinese medicinal composition preparation treating uterus carcinoma, raw material is mainly made up by weight ratio of following components:
Gecko 3 ~ 10 parts, raw first sheet 4 ~ 10 parts, Squama Manis blood 1 ~ 5 part, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 5 ~ 15 parts, Brazilian Acai 5 ~ 16 parts, Radix et Rhizoma Gynurae divaricatae 5 ~ 15 parts, flower of Radix Notoginseng 10 ~ 30 parts, Rhizoma Chuanxiong 8 ~ 25 parts, Radix Angelicae Sinensis 6 ~ 15 parts, Rhizoma Curcumae 2 ~ 8 parts, brown 2 ~ 8 parts of blood, Radix Gentianae 1 ~ 5 part, Herba Dendrobii 5 ~ 15 parts, Cordyceps 2 ~ 6 parts, Radix Panacis Quinquefolii 2 ~ 6 parts, Radix Clematidis 4 ~ 10 parts, Ramulus et Folium Tupidanthi celyptrati 6 ~ 13 parts, 2 ~ 6 parts of Rhizoma Curcumae Longae, 8 ~ 40 parts of Radix Glycyrrhizae.
The Chinese medicinal composition preparation of the above treatment uterus carcinoma, it is preferable that be mainly made up by weight ratio of following components: Gecko 6 parts, raw first sheet 7 parts, Squama Manis blood 3 parts, brucea 2 parts, Radix Sophorae Tonkinensis 2 parts, Moringa 10 parts, Brazilian Acai 12 parts, Radix et Rhizoma Gynurae divaricatae 10 parts, flower of Radix Notoginseng 20 parts, Rhizoma Chuanxiong 17 parts, Radix Angelicae Sinensis 12 parts, Rhizoma Curcumae 5 parts, brown 5 parts of blood, Radix Gentianae 3 parts, Herba Dendrobii 10 parts, Cordyceps 4 parts, Radix Panacis Quinquefolii 4 parts, Radix Clematidis 7 parts, Ramulus et Folium Tupidanthi celyptrati 10 parts, 4 parts of Rhizoma Curcumae Longae, 17 parts of Radix Glycyrrhizae.
The Chinese medicinal composition preparation of the above treatment uterus carcinoma, can add customary adjuvant by practice of pharmacy and make any dosage form of clinical acceptance; As preferably, described dosage form is capsule.
Preferably, what described Moringa was selected is Moringa rhizome.
The production technology of the Chinese medicinal composition preparation of above-described treatment uterus carcinoma, comprises the following steps:
(1) following component is weighed by weight: Gecko 3 ~ 10 parts, raw first sheet 4 ~ 10 parts, Squama Manis blood 1 ~ 5 part, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 5 ~ 15 parts, Brazilian Acai 5 ~ 16 parts, Radix et Rhizoma Gynurae divaricatae 5 ~ 15 parts, flower of Radix Notoginseng 10 ~ 30 parts, Rhizoma Chuanxiong 8 ~ 25 parts, Radix Angelicae Sinensis 6 ~ 15 parts, Rhizoma Curcumae 2 ~ 8 parts, brown 2 ~ 8 parts of blood, Radix Gentianae 1 ~ 5 part, Herba Dendrobii 5 ~ 15 parts, Cordyceps 2 ~ 6 parts, Radix Panacis Quinquefolii 2 ~ 6 parts, Radix Clematidis 4 ~ 10 parts, Ramulus et Folium Tupidanthi celyptrati 6 ~ 13 parts, 2 ~ 6 parts of Rhizoma Curcumae Longae, 8 ~ 40 parts of Radix Glycyrrhizae;
(2) first sheet and Cordyceps grind into powder respectively are given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, standby;
(4) Brazilian Acai extracts and makes acai berry extract, standby;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Rhizoma Curcumae, blood is brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis, Ramulus et Folium Tupidanthi celyptrati, Rhizoma Curcumae Longae and Radix Glycyrrhizae, add the water of 6 ~ 10 times of weight of said components, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, adding Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) take Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
The main Gecko of Chinese medicinal composition preparation of the present invention, raw first sheet, Squama Manis blood, brucea, Radix Sophorae Tonkinensis, Moringa, Brazilian Acai, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Rhizoma Curcumae, blood are brown, Radix Gentianae, Herba Dendrobii, Cordyceps, Radix Panacis Quinquefolii, Radix Clematidis, Ramulus et Folium Tupidanthi celyptrati, Rhizoma Curcumae Longae and Radix Glycyrrhizae composition, in side, effect of each Chinese medicine is:
Gecko: record according to " Japan hanako materia medica ", can control lung qi, antitussive, and logical menstruation, lower stranguria caused by urinary stone and control blood;
Raw first sheet: the routed carbuncle of detumescence, searches wind active, stimulating milk secretion of stimulating the menstrual flow; For treating carbuncle skin ulcer kind, anemofrigid-damp arthralgia, amenorrhea;
Squama Manis blood: the diseases such as stimulating milk secretion, detumescence and apocenosis, arthralgia, numbness contracture of stimulating the menstrual flow for treatment;
Brucea: Oleum Fructus Bruceae has good anticancer effect, is mainly used in pulmonary carcinoma, cervical cancer also has the tumor of digestive tract aspect; Oleum Fructus Bruceae can suppress DNA of tumor cell to carry out replicating the increasing tumor cell of generation on the one hand, still further aspect can enter directly into the inside of cancer cell, then allow necrocytosis, be discharged to the external of human body, or swallowed by the phagocyte of human body;
Radix Sophorae Tonkinensis: have heat-clearing and toxic substances removing, effect of detumescence sore-throat relieving; Record according to " Bencao Jingshu ", Radix Sophorae Tonkinensis, sweet so and poison, cold obtain poor gas so heat extraction, all poison Bi Rebixin, the taste of sweetness and bitterness, then all poison are explained by oneself, therefore for the medicine-feeding of removing toxic substances heat clearing away;
Moringa: be the plant containing abundant high nutritive value, the advantage with high protein, low lipid, high microsteping, homovitamin, containing its life mineral such as A, B, C and protein, calcium, potassium, ferrum of dimension; Can physical strength reinforcing, treatment anemia, suppress pathogenic bacteria, drive away parasite;
Brazilian Acai: can help wound healing, purify the blood, improves the diseases such as anemia, diarrhoea, fever, hemorrhage, jaundice, hepatic disease; Containing vitamin A, B1, B2, B3, B6 and B12, also have vitamin C, D, E and 17 kinds of essential minerals, polyphenoils therein and vitamin A, C and E, can effectively accelerate human body cell growth, repair impaired skin;
Radix et Rhizoma Gynurae divaricatae: there is effect of blood sugar lowering, clearing away heat and cooling blood, promoting blood circulation and stopping pain, hemostasis;
Flower of Radix Notoginseng: have effect of heat clearing away, suppressing the hyperactive liver, blood pressure lowering, recent studies indicate that, containing anti-cancer active matters such as arasaponin, beta-elemene, trace element-selenium in Radix Notoginseng; The Rb1 of arasaponin 120ug/ml concentration can make cultured tumor cells 92% be suppressed, and the suppression ratio of Panax Notoginseng saponin R d is then 79%; The hepatoma carcinoma cell cultivated is had obvious inhibitory action by Panax Notoginseng saponin R h1; Panax Notoginseng saponin R h2 has stronger anti-tumor activity, and Denucleation can be induced to become non-cancerous cells; Additionally, arasaponin and Radix Notoginseng polysaccharide energy enhancing human body immunity function, treatment cancer there is certain assosting effect;
Rhizoma Chuanxiong: for blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go scattered, up up to top, mountain peak; Enter again blood system, descending up to the sea of blood; Can tonifying liver blood, profit liver is dry, mends wind empty;
Radix Angelicae Sinensis: have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation, anti-old, immune effect anticancer, anti-ageing; Being but also widely used for various tumor, especially gynecological tumor, with QI and blood stagnation, cohesion person is the most suitable for blood stasis; Monocytes/macrophages system is had obvious stimulation by Radix Angelicae Sinensis and extract sodium ferulate and Radix Angelicae Sinensis polysaccharide thereof, and the body of immunologic hypofunction is also had immune regulation and restitution;
Rhizoma Curcumae: cure mainly coagulation of QI-blood, trusted subordinate's distending pain, lump in the abdomen, gather, dyspepsia does not disappear, women's blood stasis amenorrhea, traumatic injury are had a pain; Tuber claims " green filament Radix Curcumae ", has the function of promoting QI circulation for relieving depression, removing blood stasis with potent drugs, pain relieving; Curcumenol that Rhizoma Curcumae contains and curdione, can directly suppress to destroy tumor cell, but also can strengthen the immunogenicity of cell, thus promoting the body immunoreation to tumor;
Sanguis Draxonis: there is analgesic therapy of invigorating blood circulation, removing stasis to stop bleeding, effect of promoting tissue regeneration and ulcer healing;
Radix Gentianae: for damp and hot yellow cellulitis, swelling of the vulva pudendal pruritus, leukorrhagia, eczema pruritus, deafness, hypochondriac pain, bitter taste, convulsion with spasms; The erythricine that Radix Gentianae contains has significant antiphlogistic effects;
Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat. Losing for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision; Record according to " herbal classic ", the main damaging the spleen and stomach of Herba Dendrobii, eliminating impediment, the therapeutic method to keep the adverse QI flowing downwards, tonifying five ZANG-organs asthenia weakness and emaciation, reinforcing YIN-essence, for a long time the thick the intestines and stomach of clothes;
Cordyceps: can the immunity of enhancing body, nourishing lung and kidney; The increased activity of natural killer cell can be made, thus playing an important role in anticancer, viral infection resisting;
Radix Panacis Quinquefolii: boosting qi and nourishing yin, clearing away heat and promoting production of body fluid; It is qi-tonifying health-care first-selection medical material, it is possible to promote serum albumin synthesis, bone marrow protein synthesis, organ protein's synthesis etc., improves immunity of organisms, it is suppressed that growth of cancer cells, be effective against cancer;
Radix Clematidis: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain; For rheumatic arthralgia, numb limbs and tense tendons, muscle arteries and veins contracture, joint stuffiness, bone is choked with sobs larynx;
Ramulus et Folium Tupidanthi celyptrati: for relaxing muscles and tendons and activating QI and blood in the collateral, circulation of qi promoting damp eliminating, cold expelling dispels the wind, eliminating dampness to stop diarrhea;
Rhizoma Curcumae Longae: removing blood stasis, circulation of qi promoting, stimulate the menstrual flow, pain relieving; Controlling trusted subordinate's feeling of fullness distending pain, brachialgia, lump in the abdomen, women's blood stasis amenorrhea, puerperal, the stasis of blood stopped stomachache, injury from falling down, carbuncle;
Radix Glycyrrhizae: function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc.; Can also be used for the strong of mediation some drugs.
In the present invention, Gecko, Fructus Bruceae, flower of Radix Notoginseng, Rhizoma Curcumae have the effect killing cancerous cell; Raw first sheet, Squama Manis blood, Radix et Rhizoma Gynurae divaricatae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Sanguis Draxonis, Radix Clematidis, Ramulus et Folium Tupidanthi celyptrati and Rhizoma Curcumae Longae have effect of blood circulation promoting and blood stasis dispelling, wind-expelling pain-stopping; Flower of Radix Notoginseng, Cordyceps, Radix Panacis Quinquefolii have effect of enhancing immunity, and antitumor also has certain assosting effect; Radix Sophorae Tonkinensis is used for heat clearing away of detoxifying; Radix Gentianae, Radix Glycyrrhizae have anti-inflammatory efficacy; Radix Glycyrrhizae, for being in harmonious proportion the property of medicine of drastic remedy, alleviates the medicine stimulation to organs such as stomaches; Moringa, Brazilian Acai, Radix Panacis Quinquefolii, Herba Dendrobii can reinforcing stomach reg fluid, supplement the vitamin of needed by human body and mineral, improve that patient occurs in antagonism cancer disease process feel sick, become thin, weak, the ill symptoms such as have no appetite, reduce the medicine damage to human body; The present invention reasonable compatibility by above-mentioned Chinese medicine, with strengthening the body resistance, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, blocking-up cancerous cell, improves immunity of organisms, is finally reached the purpose curing uterus carcinoma.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, but protection scope of the present invention is not limited to following example:
One, the preparation of the Chinese medicinal composition preparation of uterus carcinoma is treated
Embodiment 1
A kind of Chinese medicinal composition preparation treating uterus carcinoma, raw material is mainly made up by weight ratio of following components: Gecko 6 parts, raw first sheet 7 parts, Squama Manis blood 3 parts, brucea 2 parts, Radix Sophorae Tonkinensis 2 parts, Moringa 10 parts, Brazilian Acai 12 parts, Radix et Rhizoma Gynurae divaricatae 10 parts, flower of Radix Notoginseng 20 parts, Rhizoma Chuanxiong 17 parts, Radix Angelicae Sinensis 12 parts, Rhizoma Curcumae 5 parts, brown 5 parts of blood, Radix Gentianae 3 parts, Herba Dendrobii 10 parts, Cordyceps 4 parts, Radix Panacis Quinquefolii 4 parts, Radix Clematidis 7 parts, Ramulus et Folium Tupidanthi celyptrati 10 parts, 4 parts of Rhizoma Curcumae Longae, 17 parts of Radix Glycyrrhizae.
What described Moringa was selected is Moringa rhizome.
The production technology of above-mentioned Chinese medicinal composition preparation is:
(1) component in above-mentioned formula is weighed by weight;
(2) first sheet and Cordyceps grind into powder respectively are given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, standby;
(4) Brazilian Acai extracts and makes acai berry extract, standby;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Rhizoma Curcumae, blood is brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis, Ramulus et Folium Tupidanthi celyptrati, Rhizoma Curcumae Longae and Radix Glycyrrhizae, add the water of 6 ~ 10 times of weight of said components, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, adding Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) take Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Embodiment 2
A kind of Chinese medicinal composition preparation treating uterus carcinoma, raw material is mainly made up by weight ratio of following components: Gecko 3 parts, raw first sheet 4 parts, Squama Manis blood 1 part, brucea 1 part, Radix Sophorae Tonkinensis 1 part, Moringa 5 parts, Brazilian Acai 5 parts, Radix et Rhizoma Gynurae divaricatae 5 parts, flower of Radix Notoginseng 10 parts, Rhizoma Chuanxiong 8 parts, Radix Angelicae Sinensis 6 parts, Rhizoma Curcumae 2 parts, brown 2 parts of blood, Radix Gentianae 1 part, Herba Dendrobii 5 parts, Cordyceps 2 parts, Radix Panacis Quinquefolii 2 parts, Radix Clematidis 4 parts, Ramulus et Folium Tupidanthi celyptrati 6 parts, 2 parts of Rhizoma Curcumae Longae, 8 parts of Radix Glycyrrhizae.
What described Moringa was selected is Moringa rhizome.
The production technology of above-mentioned Chinese medicinal composition preparation is:
(1) component in above-mentioned formula is weighed by weight;
(2) first sheet and Cordyceps grind into powder respectively are given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, standby;
(4) Brazilian Acai extracts and makes acai berry extract, standby;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Rhizoma Curcumae, blood is brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis, Ramulus et Folium Tupidanthi celyptrati, Rhizoma Curcumae Longae and Radix Glycyrrhizae, add the water of 6 ~ 10 times of weight of said components, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, adding Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) take Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Embodiment 3
A kind of Chinese medicinal composition preparation treating uterus carcinoma, raw material is mainly made up by weight ratio of following components: Gecko 10 parts, raw first sheet 10 parts, Squama Manis blood 5 parts, brucea 3 parts, Radix Sophorae Tonkinensis 3 parts, Moringa 15 parts, Brazilian Acai 16 parts, Radix et Rhizoma Gynurae divaricatae 15 parts, flower of Radix Notoginseng 30 parts, Rhizoma Chuanxiong 25 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Curcumae 8 parts, brown 8 parts of blood, Radix Gentianae 5 parts, Herba Dendrobii 15 parts, Cordyceps 6 parts, Radix Panacis Quinquefolii 6 parts, Radix Clematidis 10 parts, Ramulus et Folium Tupidanthi celyptrati 13 parts, 6 parts of Rhizoma Curcumae Longae, 40 parts of Radix Glycyrrhizae.
What described Moringa was selected is Moringa rhizome.
The production technology of above-mentioned Chinese medicinal composition preparation is:
(1) component in above-mentioned formula is weighed by weight;
(2) first sheet and Cordyceps grind into powder respectively are given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, standby;
(4) Brazilian Acai extracts and makes acai berry extract, standby;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Rhizoma Curcumae, blood is brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis, Ramulus et Folium Tupidanthi celyptrati, Rhizoma Curcumae Longae and Radix Glycyrrhizae, add the water of 6 ~ 10 times of weight of said components, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, adding Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) take Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
Two, clinical practice
1, the selection of case:
Select traditional Chinese medical science uterus tumor patient, through 75 example clinical observations.
(1) inclusive criteria:
A. age women between 38-65 year, 52.8 years old mean age.
B. tcm diagnosis uterus carcinoma is standard: limb is soft unable, deficient seriously, lower abdomen drop, suppress swollen pain, uterus CT visual tumors.
C. can partner treatment, the patient of further consultation on time.
(2) exclusion standard
A. the age is below 38 years old or over-65s person.
B. suffers from other serious disease
C. gestation or preparation gravid woman, women breast-feeding their children.
D. allergic constitution or to multi-medicament allergy sufferers.
E. not by regulation medication or therapy discontinued, it is impossible to judge curative effect or data is not congruent affects the treatment or safety judgement person.
2, clinical trial:
(1) efficacy determination:
A. effective: body constitution strengthens, extremity are strong, and lower abdomen is uncomfortable substantially to be alleviated, and CT shows that uterus tumor tumor body reduces, and other position does not find nascent tumor.
B. effective: weak symptom makes moderate progress, lower abdomen discomfort is alleviated to some extent, and uterus tumor tumor body has no growth, and other position does not find nascent tumor.
C. invalid: disease is unchanged, uterus tumor tumor body increases, or other position finds nascent tumor.
(2), during clinical experiment, other medicines and health nutrient are withdrawn. Take the preparation (each embodiment is observed through 25 example patient clinicals) of embodiment 1 ~ 3 in the present invention, observe 3 months, be a course for the treatment of. Instructions of taking: every day 3 times, each 6 capsules, every capsules includes traditional Chinese medicine fine powder and extract 0.25 gram, warm water delivery service after meal, the results detailed in following table:
| Group | Effective | Effectively | Invalid | Effective percentage |
| Embodiment 1 | 12 | 11 | 2 | 92% |
| Embodiment 2 | 10 | 12 | 3 | 88% |
| Embodiment 3 | 10 | 10 | 5 | 80% |
Result shows: adopt the embodiment of the present invention 1 ~ 3 to treat, wherein, the best results of embodiment 1, effective percentage reaches 92%, the effective percentage of embodiment 2,3 is also more than 80%, general effect of the present invention is better, the symptom such as can be obviously improved that patient is weak, pain, anorexia, lower abdomen of becoming thin are uncomfortable, and the mental status is good.
Claims (6)
1. the Chinese medicinal composition preparation treating uterus carcinoma, it is characterised in that raw material is mainly made up by weight ratio of following components:
Gecko 3 ~ 10 parts, raw first sheet 4 ~ 10 parts, Squama Manis blood 1 ~ 5 part, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 5 ~ 15 parts, Brazilian Acai 5 ~ 16 parts, Radix et Rhizoma Gynurae divaricatae 5 ~ 15 parts, flower of Radix Notoginseng 10 ~ 30 parts, Rhizoma Chuanxiong 8 ~ 25 parts, Radix Angelicae Sinensis 6 ~ 15 parts, Rhizoma Curcumae 2 ~ 8 parts, brown 2 ~ 8 parts of blood, Radix Gentianae 1 ~ 5 part, Herba Dendrobii 5 ~ 15 parts, Cordyceps 2 ~ 6 parts, Radix Panacis Quinquefolii 2 ~ 6 parts, Radix Clematidis 4 ~ 10 parts, Ramulus et Folium Tupidanthi celyptrati 6 ~ 13 parts, 2 ~ 6 parts of Rhizoma Curcumae Longae, 8 ~ 40 parts of Radix Glycyrrhizae.
2. the Chinese medicinal composition preparation for the treatment of uterus carcinoma according to claim 1, it is characterised in that raw material is mainly made up by weight ratio of following components:
Gecko 6 parts, raw first sheet 7 parts, Squama Manis blood 3 parts, brucea 2 parts, Radix Sophorae Tonkinensis 2 parts, Moringa 10 parts, Brazilian Acai 12 parts, Radix et Rhizoma Gynurae divaricatae 10 parts, flower of Radix Notoginseng 20 parts, Rhizoma Chuanxiong 17 parts, Radix Angelicae Sinensis 12 parts, Rhizoma Curcumae 5 parts, brown 5 parts of blood, Radix Gentianae 3 parts, Herba Dendrobii 10 parts, Cordyceps 4 parts, Radix Panacis Quinquefolii 4 parts, Radix Clematidis 7 parts, Ramulus et Folium Tupidanthi celyptrati 10 parts, 4 parts of Rhizoma Curcumae Longae, 17 parts of Radix Glycyrrhizae.
3. the Chinese medicinal composition preparation of the treatment uterus carcinoma according to any one of claim 1 ~ 2, it is characterised in that:
Described Chinese medicinal composition preparation adds customary adjuvant by practice of pharmacy and makes any dosage form of clinical acceptance.
4. the Chinese medicinal composition preparation for the treatment of uterus carcinoma according to claim 3, it is characterised in that:
Described dosage form is capsule.
5. the Chinese medicinal composition preparation for the treatment of uterus carcinoma according to claim 1, it is characterised in that:
What described Moringa was selected is Moringa rhizome.
6. the production technology of a kind of Chinese medicinal composition preparation treating uterus carcinoma according to claim 1, it is characterised in that comprise the following steps:
(1) following component is weighed by weight: Gecko 3 ~ 10 parts, raw first sheet 4 ~ 10 parts, Squama Manis blood 1 ~ 5 part, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 5 ~ 15 parts, Brazilian Acai 5 ~ 16 parts, Radix et Rhizoma Gynurae divaricatae 5 ~ 15 parts, flower of Radix Notoginseng 10 ~ 30 parts, Rhizoma Chuanxiong 8 ~ 25 parts, Radix Angelicae Sinensis 6 ~ 15 parts, Rhizoma Curcumae 2 ~ 8 parts, brown 2 ~ 8 parts of blood, Radix Gentianae 1 ~ 5 part, Herba Dendrobii 5 ~ 15 parts, Cordyceps 2 ~ 6 parts, Radix Panacis Quinquefolii 2 ~ 6 parts, Radix Clematidis 4 ~ 10 parts, Ramulus et Folium Tupidanthi celyptrati 6 ~ 13 parts, 2 ~ 6 parts of Rhizoma Curcumae Longae, 8 ~ 40 parts of Radix Glycyrrhizae;
(2) first sheet and Cordyceps grind into powder respectively are given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, standby;
(4) Brazilian Acai extracts and makes acai berry extract, standby;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Rhizoma Curcumae, blood is brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis, Ramulus et Folium Tupidanthi celyptrati, Rhizoma Curcumae Longae and Radix Glycyrrhizae, add the water of 6 ~ 10 times of weight of said components, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, adding Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) take Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, make granule, load capsule, obtain capsule.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103611094A (en) * | 2013-12-12 | 2014-03-05 | 王学玲 | Medicament for treating cervical cancer |
| CN103877508A (en) * | 2014-03-28 | 2014-06-25 | 王俊杰 | Traditional Chinese medicine composition for treating metrocarcinoma |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103611094A (en) * | 2013-12-12 | 2014-03-05 | 王学玲 | Medicament for treating cervical cancer |
| CN103877508A (en) * | 2014-03-28 | 2014-06-25 | 王俊杰 | Traditional Chinese medicine composition for treating metrocarcinoma |
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| Title |
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| 周绪堂: "《实用肿瘤诊疗手册》", 30 November 1997, 江西科学技术出版社 * |
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