CN105561202A - Traditional Chinese medicine composition for treating uterus cancer - Google Patents
Traditional Chinese medicine composition for treating uterus cancer Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating uterus cancer. The traditional Chinese medicine composition is mainly prepared from, by weight, 3-10 parts of tokay gecko, 4-10 parts of raw pangolin scale, 1-5 parts of pangolin blood, 1-3 parts of java brucea fruit, 1-3 parts of radix sophorae subprostratae, 8-18 parts of horseradish tree, 5-16 parts of acai berry, 5-15 parts of divaricate gynura root, 10-30 parts of flos notoginseng, 8-25 parts of rhizome ligusticum wallichii, 8-25 parts of radix angelicae sinensis, 2-7 parts of flos carthami, 2-8 parts of rhizoma curcumae, 2-8 parts of dragon blood, 1-5 parts of radix gentianae, 5-15 parts of herba dendrobii, 2-6 parts of Chinese caterpillar fungus, 2-6 parts of American ginseng, 4-10 parts of radix clematidis and 8-40 parts of liquorice root. Through reasonable compatibility of traditional Chinese medicines, the traditional Chinese medicine composition can support the healthy energy, promote blood circulation to remove blood stasis, promote qi circulation to relieve pain, prevent cancer cells and improve the immunity of the organism, so that uterus cancer can be treated.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly a kind of Chinese medicine composition for the treatment of uterus carcinoma.
Background technology
Uterus carcinoma is one of modal malignant tumor of gynecological, and uterus carcinoma comprises carcinoma of corpus uteri (also known as carcinoma of endometrium) and cervical cancer.In the world, about have more than 20 ten thousand women to die from cervical cancer every year, in developing country, cervical cancer then belongs to common multiple gynecological tumor, the seniority among brothers and sisters umber one.Uterus carcinoma refers to the malignant tumor occurring in utero vaginal portion and cervical canal, the transfer of cervical cancer, can to adjacent tissue and organ direct extension, down to fornix vaginae and vaginal wall, upwards can invade body of uterus, can pelvic tissue be invaded to both sides, can bladder be invaded forward, can rectum be invaded backward.
Be intended to the Chinese medicine for the treatment of uterus tumor at present, mainly there is the deficiency of several aspect: one is that drug effect is not remarkable; Two be take effect slower; Three is can not treating both the principal and secondary aspects of a disease.A lot of uterus carcinoma patient effectively can not control growth, the metastasis and extension of tumor because of medicine, or drug administration does not recur again later, thus have impact on the time of existence.
Summary of the invention
The invention provides a kind of Chinese medicine composition for the treatment of uterus carcinoma, have significant therapeutic effect to uterus carcinoma.
For achieving the above object, technical scheme of the present invention is:
Treat a Chinese medicine composition for uterus carcinoma, it is made by weight ratio primarily of following component:
Gecko 3 ~ 10 parts, raw first sheet 4 ~ 10 parts, Squama Manis blood 1 ~ 5 part, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 8 ~ 18 parts, Brazilian Acai 5 ~ 16 parts, Radix et Rhizoma Gynurae divaricatae 5 ~ 15 parts, flower of Radix Notoginseng 10 ~ 30 parts, Rhizoma Chuanxiong 8 ~ 25 parts, Radix Angelicae Sinensis 8 ~ 25 parts, 2 ~ 7 parts, Flos Carthami, Rhizoma Curcumae 2 ~ 8 parts, brown 2 ~ 8 parts of blood, Radix Gentianae 1 ~ 5 part, Herba Dendrobii 5 ~ 15 parts, Cordyceps 2 ~ 6 parts, Radix Panacis Quinquefolii 2 ~ 6 parts, Radix Clematidis 4 ~ 10 parts, 8 ~ 40 parts, Radix Glycyrrhizae.
The Chinese medicine composition of the above treatment uterus carcinoma, its more specifically technical scheme be: it is made by weight ratio primarily of following component: Gecko 4 ~ 8 parts, raw first sheet 5 ~ 9 parts, Squama Manis blood 2 ~ 4 parts, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 10 ~ 17 parts, Brazilian Acai 7 ~ 14 parts, Radix et Rhizoma Gynurae divaricatae 7 ~ 13 parts, flower of Radix Notoginseng 15 ~ 25 parts, Rhizoma Chuanxiong 10 ~ 22 parts, Radix Angelicae Sinensis 10 ~ 22 parts, 3 ~ 6 parts, Flos Carthami, Rhizoma Curcumae 3 ~ 7 parts, brown 3 ~ 6 parts of blood, Radix Gentianae 2 ~ 4 parts, Herba Dendrobii 7 ~ 13 parts, Cordyceps 3 ~ 5 parts, Radix Panacis Quinquefolii 3 ~ 5 parts, Radix Clematidis 6 ~ 8 parts, 12 ~ 35 parts, Radix Glycyrrhizae.
The Chinese medicine composition of the above treatment uterus carcinoma, preferably makes primarily of following component: Gecko 6 parts, raw first sheet 7 parts, Squama Manis blood 3 parts, brucea 2 parts, Radix Sophorae Tonkinensis 2 parts, Moringa 13 parts, Brazilian Acai 12 parts, Radix et Rhizoma Gynurae divaricatae 10 parts, flower of Radix Notoginseng 20 parts, Rhizoma Chuanxiong 17 parts, Radix Angelicae Sinensis 17 parts, 5 parts, Flos Carthami, Rhizoma Curcumae 5 parts, brown 5 parts of blood, Radix Gentianae 3 parts, Herba Dendrobii 10 parts, Cordyceps 4 parts, Radix Panacis Quinquefolii 4 parts, Radix Clematidis 7 parts, 17 parts, Radix Glycyrrhizae by weight ratio.
The Chinese medicine composition of the above treatment uterus carcinoma, can add by practice of pharmacy any dosage form that customary adjuvant makes clinical acceptance; As preferably, described dosage form is capsule.
Preferably, what described Moringa was selected is Moringa rhizome.
The preparation method of the Chinese medicine composition of above-described treatment uterus carcinoma, comprises the following steps:
(1) following component is taken by weight: Gecko 3 ~ 10 parts, raw first sheet 4 ~ 10 parts, Squama Manis blood 1 ~ 5 part, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 8 ~ 18 parts, Brazilian Acai 5 ~ 16 parts, Radix et Rhizoma Gynurae divaricatae 5 ~ 15 parts, flower of Radix Notoginseng 10 ~ 30 parts, Rhizoma Chuanxiong 8 ~ 25 parts, Radix Angelicae Sinensis 8 ~ 25 parts, 2 ~ 7 parts, Flos Carthami, Rhizoma Curcumae 2 ~ 8 parts, brown 2 ~ 8 parts of blood, Radix Gentianae 1 ~ 5 part, Herba Dendrobii 5 ~ 15 parts, Cordyceps 2 ~ 6 parts, Radix Panacis Quinquefolii 2 ~ 6 parts, Radix Clematidis 4 ~ 10 parts, 8 ~ 40 parts, Radix Glycyrrhizae;
(2) first sheet and Cordyceps grind into powder is respectively given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, for subsequent use;
(4) Brazilian Acai extracts and makes acai berry extract, for subsequent use;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Curcumae, blood brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis and Radix Glycyrrhizae, add the water of said components 6 ~ 10 times of weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, add Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) get Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, makes granule, incapsulates, obtain capsule.
The main Gecko of Chinese medicine composition of the present invention, raw first sheet, Squama Manis blood, brucea, Radix Sophorae Tonkinensis, Moringa, Brazilian Acai, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Curcumae, blood are brown, Radix Gentianae, Herba Dendrobii, Cordyceps, Radix Panacis Quinquefolii, Radix Clematidis and Radix Glycyrrhizae composition, and in side, effect of each Chinese medicine is:
Gecko: record according to " Japan hanako materia medica ", can lung qi be controlled, antitussive, and logical menstruation, lower stranguria caused by urinary stone and control blood;
Raw first sheet: the routed carbuncle of detumescence, searches wind active, stimulating milk secretion of stimulating the menstrual flow; Be used for the treatment of carbuncle skin ulcer kind, anemofrigid-damp arthralgia, amenorrhea;
Squama Manis blood: be used for the treatment of stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, arthralgia, the diseases such as numbness contracture;
Brucea: Oleum Fructus Bruceae has good anticancer effect, is mainly used in pulmonary carcinoma, tumor that cervical cancer also has digestive tract aspect; Oleum Fructus Bruceae can carry out copying the increasing tumor cell of generation by inhibition tumor cell DNA on the one hand, directly can enter into the inside of cancer cell in addition on the one hand, then allow necrocytosis, be discharged to the external of human body, or engulfed by the phagocyte of human body;
Radix Sophorae Tonkinensis: have heat-clearing and toxic substances removing, effect of detumescence sore-throat relieving; Record according to " Bencao Jingshu ", Radix Sophorae Tonkinensis, sweet so and poison, cold so heat extraction, all malicious Bi Rebixin, obtain poor gas, the taste of sweetness and bitterness, then all poison are explained by oneself, therefore are the medicine-feeding of removing toxic substances heat clearing away;
Moringa: be the plant containing enriching high nutritive value, has the advantage of high protein, low lipid, high microsteping, homovitamin, containing its mineral such as life A, B, C and protein, calcium, potassium, ferrum etc. of dimension; Can physical strength reinforcing, treatment anemia, suppress pathogenic bacteria, drive away parasite;
Brazilian Acai: can help wound healing, purify the blood, improves anemia, diarrhoea, fever, hemorrhage, the disease such as jaundice, hepatic disease; Containing vitamin A, B1, B2, B3, B6 and B12, also have vitamin C, D, E and 17 kinds of essential minerals, polyphenoils wherein and vitamin A, C and E, effectively can accelerate human body cell growth, repair impaired skin;
Radix et Rhizoma Gynurae divaricatae: the effect with blood sugar lowering, clearing away heat and cooling blood, promoting blood circulation and stopping pain, hemostasis;
Flower of Radix Notoginseng: the effect with heat clearing away, suppressing the hyperactive liver, blood pressure lowering, research in recent years shows, containing anti-cancer active matters such as arasaponin, beta-elemene, trace element-selenium in Radix Notoginseng; The Rb1 of arasaponin 120ug/ml concentration can make cultured tumor cells 92% be suppressed, and the suppression ratio of Panax Notoginseng saponin R d is then 79%; Panax Notoginseng saponin R h1 has obvious inhibitory action to the hepatoma carcinoma cell of cultivating; Panax Notoginseng saponin R h2 has stronger anti-tumor activity, and can be reversed into non-cancerous cells by inducing cancer cell; In addition, arasaponin and Radix Notoginseng polysaccharide energy enhancing human body immunity function, have certain assosting effect to Therapeutic cancer;
Rhizoma Chuanxiong: for blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, and the up mountain peak that reaches is pushed up; Enter blood system again, descendingly reach the sea of blood; Can tonifying liver blood, profit liver is dry, mends wind empty;
Radix Angelicae Sinensis: there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation, anticancer, anti-ageing anti-old, immune effect; Also can be widely used in various tumor, especially gynecological tumor, stagnate with QI and blood, cohesion person is the most suitable for blood stasis; Radix Angelicae Sinensis and extract sodium ferulate thereof and Radix Angelicae Sinensis polysaccharide have obvious stimulation to monocytes/macrophages system, also have immune regulation and restitution to the body of immunologic hypofunction;
Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contributes to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, traumatic injury, skin infection swells and ache curative effect; Containing Flos Carthami polysaccharide in Flos Carthami, can lymphocyte transformation be promoted, there is effect of enhancing immunity;
Rhizoma Curcumae: cure mainly coagulation of QI-blood, trusted subordinate's distending pain, lump in the abdomen, gather, dyspepsia does not disappear, women's blood stasis amenorrhea, traumatic injury are had a pain; Tuber claims " green filament Radix Curcumae ", has the function of promoting QI circulation for relieving depression, removing blood stasis with potent drugs, pain relieving; The curcumenol that Rhizoma Curcumae contains and curdione, directly can suppress to destroy tumor cell, but also can strengthen the immunogenicity of cell, thus promote that body is to the immunoreation of tumor;
Sanguis Draxonis: there is analgesic therapy of invigorating blood circulation, removing stasis to stop bleeding, effect of promoting tissue regeneration and ulcer healing;
Radix Gentianae: for damp and hot yellow cellulitis, swelling of the vulva pudendal pruritus, leukorrhagia, eczema pruritus, deafness, hypochondriac pain, bitter taste, convulsion with spasms; The erythricine that Radix Gentianae contains has significant antiphlogistic effects;
Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision; Record according to " herbal classic ", the main damaging the spleen and stomach of Herba Dendrobii, eliminating impediment, the therapeutic method to keep the adverse QI flowing downwards, tonifying five ZANG-organs asthenia weakness and emaciation, reinforcing YIN-essence, takes thick the intestines and stomach for a long time;
Cordyceps: can the immunity of enhancing body, nourishing lung and kidney; The increased activity of natural killer cell can be made, thus play an important role in anticancer, viral infection resisting;
Radix Panacis Quinquefolii: boosting qi and nourishing yin, clearing away heat and promoting production of body fluid; Be the first-selected medical material of qi-tonifying health-care, can promote that serum albumin synthesizes, bone marrow protein synthesizes, organ protein synthesizes, improve immunity of organisms, anticancer grows, and effectively resists cancer;
Radix Clematidis: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain; For rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone is choked with sobs larynx;
Radix Glycyrrhizae: function cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc.; Also can be used for being in harmonious proportion the strong of some drugs.
In the present invention, Gecko, Fructus Bruceae, flower of Radix Notoginseng, Rhizoma Curcumae have the effect killing cancerous cell; Raw first sheet, Squama Manis blood, Radix et Rhizoma Gynurae divaricatae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami, Sanguis Draxonis, Radix Clematidis have effect of blood circulation promoting and blood stasis dispelling, wind-expelling pain-stopping; Flower of Radix Notoginseng, Flos Carthami, Cordyceps, Radix Panacis Quinquefolii have effect of enhancing immunity, also have certain assosting effect to antitumor; Radix Sophorae Tonkinensis is for heat clearing away of detoxifying; Radix Gentianae, Radix Glycyrrhizae have anti-inflammatory efficacy; Radix Glycyrrhizae, for being in harmonious proportion the property of medicine of drastic remedy, alleviates the stimulation of medicine to organs such as stomaches; Moringa, Brazilian Acai, Radix Panacis Quinquefolii, Herba Dendrobii can reinforcing stomach reg fluids, supplement vitamin and the mineral of needed by human body, improve that patient occurs in antagonism cancer disease process feel sick, become thin, weak, the ill symptoms such as to have no appetite, reduce medicine to the damage of human body; The present invention, by the reasonable compatibility of above-mentioned Chinese medicine, with strengthening the body resistance, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, blocking-up cancerous cell, improves immunity of organisms, finally reaches the object of curing uterus carcinoma.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, but protection scope of the present invention is not limited to following examples:
One, the preparation of the Chinese medicine composition of uterus carcinoma is treated
Embodiment 1
Treat a Chinese medicine composition for uterus carcinoma, make by weight ratio primarily of following component: Gecko 6 parts, raw first sheet 7 parts, Squama Manis blood 3 parts, brucea 2 parts, Radix Sophorae Tonkinensis 2 parts, Moringa 13 parts, Brazilian Acai 12 parts, Radix et Rhizoma Gynurae divaricatae 10 parts, flower of Radix Notoginseng 20 parts, Rhizoma Chuanxiong 17 parts, Radix Angelicae Sinensis 17 parts, 5 parts, Flos Carthami, Rhizoma Curcumae 5 parts, brown 5 parts of blood, Radix Gentianae 3 parts, Herba Dendrobii 10 parts, Cordyceps 4 parts, Radix Panacis Quinquefolii 4 parts, Radix Clematidis 7 parts, 17 parts, Radix Glycyrrhizae.
What described Moringa was selected is Moringa rhizome.
The preparation method of above-mentioned Chinese medicine composition is:
(1) component in above-mentioned formula is taken by weight;
(2) first sheet and Cordyceps grind into powder is respectively given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, for subsequent use;
(4) Brazilian Acai extracts and makes acai berry extract, for subsequent use;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Curcumae, blood brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis and Radix Glycyrrhizae, add the water of said components 6 ~ 10 times of weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, add Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) get Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, makes granule, incapsulates, obtain capsule.
Embodiment 2
Treat a Chinese medicine composition for uterus carcinoma, make by weight ratio primarily of following component: Gecko 3 parts, raw first sheet 4 parts, Squama Manis blood 1 part, brucea 1 part, Radix Sophorae Tonkinensis 1 part, Moringa 8 parts, Brazilian Acai 5 parts, Radix et Rhizoma Gynurae divaricatae 5 parts, flower of Radix Notoginseng 10 parts, Rhizoma Chuanxiong 8 parts, Radix Angelicae Sinensis 8 parts, 2 parts, Flos Carthami, Rhizoma Curcumae 2 parts, brown 2 parts of blood, Radix Gentianae 1 part, Herba Dendrobii 5 parts, Cordyceps 2 parts, Radix Panacis Quinquefolii 2 parts, Radix Clematidis 4 parts, 8 parts, Radix Glycyrrhizae.
What described Moringa was selected is Moringa rhizome.
The preparation method of above-mentioned Chinese medicine composition is:
(1) component in above-mentioned formula is taken by weight;
(2) first sheet and Cordyceps grind into powder is respectively given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, for subsequent use;
(4) Brazilian Acai extracts and makes acai berry extract, for subsequent use;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Curcumae, blood brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis and Radix Glycyrrhizae, add the water of said components 6 ~ 10 times of weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, add Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) get Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, makes granule, incapsulates, obtain capsule.
Embodiment 3
Treat a Chinese medicine composition for uterus carcinoma, make by weight ratio primarily of following component: Gecko 10 parts, raw first sheet 10 parts, Squama Manis blood 5 parts, brucea 3 parts, Radix Sophorae Tonkinensis 3 parts, Moringa 18 parts, Brazilian Acai 16 parts, Radix et Rhizoma Gynurae divaricatae 15 parts, flower of Radix Notoginseng 30 parts, Rhizoma Chuanxiong 25 parts, Radix Angelicae Sinensis 25 parts, 7 parts, Flos Carthami, Rhizoma Curcumae 8 parts, brown 8 parts of blood, Radix Gentianae 5 parts, Herba Dendrobii 15 parts, Cordyceps 6 parts, Radix Panacis Quinquefolii 6 parts, Radix Clematidis 10 parts, 40 parts, Radix Glycyrrhizae.
What described Moringa was selected is Moringa rhizome.
The preparation method of above-mentioned Chinese medicine composition is:
(1) component in above-mentioned formula is taken by weight;
(2) first sheet and Cordyceps grind into powder is respectively given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, for subsequent use;
(4) Brazilian Acai extracts and makes acai berry extract, for subsequent use;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Curcumae, blood brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis and Radix Glycyrrhizae, add the water of said components 6 ~ 10 times of weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, add Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) get Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, makes granule, incapsulates, obtain capsule.
Embodiment 4
Treat a Chinese medicine composition for uterus carcinoma, make by weight ratio primarily of following component: Gecko 4 parts, raw first sheet 5 parts, Squama Manis blood 2 parts, brucea 1 part, Radix Sophorae Tonkinensis 1 part, Moringa 10 parts, Brazilian Acai 7 parts, Radix et Rhizoma Gynurae divaricatae 7 parts, flower of Radix Notoginseng 15 parts, Rhizoma Chuanxiong 10 parts, Radix Angelicae Sinensis 10 parts, 3 parts, Flos Carthami, Rhizoma Curcumae 3 parts, brown 3 parts of blood, Radix Gentianae 2 parts, Herba Dendrobii 7 parts, Cordyceps 3 parts, Radix Panacis Quinquefolii 3 parts, Radix Clematidis 6 parts, 12 parts, Radix Glycyrrhizae.
What described Moringa was selected is Moringa rhizome.
The preparation method of above-mentioned Chinese medicine composition is:
(1) component in above-mentioned formula is taken by weight;
(2) first sheet and Cordyceps grind into powder is respectively given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, for subsequent use;
(4) Brazilian Acai extracts and makes acai berry extract, for subsequent use;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Curcumae, blood brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis and Radix Glycyrrhizae, add the water of said components 6 ~ 10 times of weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, add Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) get Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, makes granule, incapsulates, obtain capsule.
Embodiment 5
Treat a Chinese medicine composition for uterus carcinoma, make by weight ratio primarily of following component: Gecko 8 parts, raw first sheet 9 parts, Squama Manis blood 4 parts, brucea 3 parts, Radix Sophorae Tonkinensis 3 parts, Moringa 17 parts, Brazilian Acai 14 parts, Radix et Rhizoma Gynurae divaricatae 13 parts, flower of Radix Notoginseng 25 parts, Rhizoma Chuanxiong 22 parts, Radix Angelicae Sinensis 22 parts, 6 parts, Flos Carthami, Rhizoma Curcumae 7 parts, brown 6 parts of blood, Radix Gentianae 4 parts, Herba Dendrobii 13 parts, Cordyceps 5 parts, Radix Panacis Quinquefolii 5 parts, Radix Clematidis 8 parts, 35 parts, Radix Glycyrrhizae.
What described Moringa was selected is Moringa rhizome.
The preparation method of above-mentioned Chinese medicine composition is:
(1) component in above-mentioned formula is taken by weight;
(2) first sheet and Cordyceps grind into powder is respectively given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, for subsequent use;
(4) Brazilian Acai extracts and makes acai berry extract, for subsequent use;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Curcumae, blood brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis and Radix Glycyrrhizae, add the water of said components 6 ~ 10 times of weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, add Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) get Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, makes granule, incapsulates, obtain capsule.
Two, clinical practice
1, the selection of case:
Select traditional Chinese medical science uterus tumor patient, through 75 routine clinical observations.
(1) inclusive criteria:
A. the women of age between 38-65 year, 52.8 years old mean age.
B. tcm diagnosis uterus carcinoma is standard: limb is soft unable, seriously deficient, and lower abdomen drops, and suppresses swollen pain, uterus CT visual tumors.
C. can partner treatment, the patient of further consultation on time.
(2) exclusion standard
A. the age is below 38 years old or over-65s person.
B. other serious disease is suffered from
C. gestation or preparation gravid woman, women breast-feeding their children.
D. allergic constitution or to multi-medicament allergy sufferers.
E. not by regulation medication or therapy discontinued, cannot judge that curative effect or data are not congruent and affect the treatment or safety judgement person.
2, clinical trial:
(1) efficacy determination:
A. effective: body constitution strengthens, extremity are strong, and lower abdomen is uncomfortable obviously to be alleviated, and CT shows uterus tumor tumor body to be reduced, and other position does not find nascent tumor.
B. effective: weak symptom makes moderate progress, lower abdomen discomfort is alleviated to some extent, and uterus tumor tumor body has no growth, and other position does not find nascent tumor.
C. invalid: disease is unchanged, uterus tumor tumor body increases, or other position finds nascent tumor.
(2), during clinical experiment, other medicines and health nutrient is withdrawn.Take the preparation (each embodiment is observed through 15 routine patient clinicals) of embodiment 1 ~ 5 in the present invention, observing 3 months, is a course for the treatment of.Instructions of taking: every day 3 times, each 6 capsules, every capsules includes traditional Chinese medicine fine powder and extract 0.25 gram, warm water delivery service after meal, the results detailed in following table:
| Group | Effective | Effectively | Invalid | Effective percentage |
| Embodiment 1 | 7 | 7 | 1 | 93.3% |
| Embodiment 2 | 6 | 6 | 3 | 80% |
| Embodiment 3 | 6 | 6 | 3 | 80% |
| Embodiment 4 | 7 | 6 | 2 | 86.7% |
| Embodiment 5 | 6 | 7 | 2 | 86.7% |
Result shows: adopt the embodiment of the present invention 1 ~ 5 to treat, total effective rate reaches 86.7%, and general effect is better, the symptom such as obviously can improve that patient is weak, pain, anorexia, lower abdomen of becoming thin are uncomfortable, and the mental status is good.
Claims (7)
1. treat a Chinese medicine composition for uterus carcinoma, it is characterized in that, it is made by weight ratio primarily of following component:
Gecko 3 ~ 10 parts, raw first sheet 4 ~ 10 parts, Squama Manis blood 1 ~ 5 part, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 8 ~ 18 parts, Brazilian Acai 5 ~ 16 parts, Radix et Rhizoma Gynurae divaricatae 5 ~ 15 parts, flower of Radix Notoginseng 10 ~ 30 parts, Rhizoma Chuanxiong 8 ~ 25 parts, Radix Angelicae Sinensis 8 ~ 25 parts, 2 ~ 7 parts, Flos Carthami, Rhizoma Curcumae 2 ~ 8 parts, brown 2 ~ 8 parts of blood, Radix Gentianae 1 ~ 5 part, Herba Dendrobii 5 ~ 15 parts, Cordyceps 2 ~ 6 parts, Radix Panacis Quinquefolii 2 ~ 6 parts, Radix Clematidis 4 ~ 10 parts, 8 ~ 40 parts, Radix Glycyrrhizae.
2. the Chinese medicine composition for the treatment of uterus carcinoma according to claim 1, is characterized in that, it is made by weight ratio primarily of following component:
Gecko 4 ~ 8 parts, raw first sheet 5 ~ 9 parts, Squama Manis blood 2 ~ 4 parts, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 10 ~ 17 parts, Brazilian Acai 7 ~ 14 parts, Radix et Rhizoma Gynurae divaricatae 7 ~ 13 parts, flower of Radix Notoginseng 15 ~ 35 parts, Rhizoma Chuanxiong 10 ~ 22 parts, Radix Angelicae Sinensis 10 ~ 22 parts, 3 ~ 6 parts, Flos Carthami, Rhizoma Curcumae 3 ~ 7 parts, brown 3 ~ 6 parts of blood, Radix Gentianae 2 ~ 4 parts, Herba Dendrobii 7 ~ 13 parts, Cordyceps 3 ~ 5 parts, Radix Panacis Quinquefolii 3 ~ 5 parts, Radix Clematidis 6 ~ 8 parts, 12 ~ 35 parts, Radix Glycyrrhizae.
3. the Chinese medicine composition for the treatment of uterus carcinoma according to claim 1, is characterized in that, it is made by weight ratio primarily of following component:
Gecko 6 parts, raw first sheet 7 parts, Squama Manis blood 3 parts, brucea 2 parts, Radix Sophorae Tonkinensis 2 parts, Moringa 13 parts, Brazilian Acai 12 parts, Radix et Rhizoma Gynurae divaricatae 10 parts, flower of Radix Notoginseng 20 parts, Rhizoma Chuanxiong 17 parts, Radix Angelicae Sinensis 17 parts, 5 parts, Flos Carthami, Rhizoma Curcumae 5 parts, brown 5 parts of blood, Radix Gentianae 3 parts, Herba Dendrobii 10 parts, Cordyceps 4 parts, Radix Panacis Quinquefolii 4 parts, Radix Clematidis 7 parts, 17 parts, Radix Glycyrrhizae.
4. the Chinese medicine composition of the treatment uterus carcinoma according to any one of claim 1 ~ 3, is characterized in that:
Described Chinese medicine composition adds by practice of pharmacy any dosage form that customary adjuvant makes clinical acceptance.
5. the Chinese medicine composition for the treatment of uterus carcinoma according to claim 4, is characterized in that:
Described dosage form is capsule.
6. the Chinese medicine composition for the treatment of uterus carcinoma according to claim 1, is characterized in that:
What described Moringa was selected is Moringa rhizome.
7. a kind of preparation method for the treatment of the Chinese medicine composition of uterus carcinoma according to claim 1, is characterized in that comprising the following steps:
(1) following component is taken by weight: Gecko 3 ~ 10 parts, raw first sheet 4 ~ 10 parts, Squama Manis blood 1 ~ 5 part, brucea 1 ~ 3 part, Radix Sophorae Tonkinensis 1 ~ 3 part, Moringa 8 ~ 18 parts, Brazilian Acai 5 ~ 16 parts, Radix et Rhizoma Gynurae divaricatae 5 ~ 15 parts, flower of Radix Notoginseng 10 ~ 30 parts, Rhizoma Chuanxiong 8 ~ 25 parts, Radix Angelicae Sinensis 8 ~ 25 parts, 2 ~ 7 parts, Flos Carthami, Rhizoma Curcumae 2 ~ 8 parts, brown 2 ~ 8 parts of blood, Radix Gentianae 1 ~ 5 part, Herba Dendrobii 5 ~ 15 parts, Cordyceps 2 ~ 6 parts, Radix Panacis Quinquefolii 2 ~ 6 parts, Radix Clematidis 4 ~ 10 parts, 8 ~ 40 parts, Radix Glycyrrhizae;
(2) first sheet and Cordyceps grind into powder is respectively given birth to;
(3) Fructus Bruceae extracts and makes Oleum Fructus Bruceae, for subsequent use;
(4) Brazilian Acai extracts and makes acai berry extract, for subsequent use;
(5) Gecko, raw first sheet powder, Squama Manis blood, Radix Sophorae Tonkinensis, Moringa, Radix et Rhizoma Gynurae divaricatae, flower of Radix Notoginseng, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami, Rhizoma Curcumae, blood brown, Radix Gentianae, Herba Dendrobii, Radix Panacis Quinquefolii, Radix Clematidis and Radix Glycyrrhizae, add the water of said components 6 ~ 10 times of weight, heating extraction 2 ~ 3 times, each 1 ~ 2 hour, filter, merging filtrate, filtrate is condensed into thick paste, add Cordyceps powder, acai berry extract and appropriate amount of starch, dry, pulverizing, get dry extract powder;
(6) get Oleum Fructus Bruceae, with the betacyclodextrin inclusion of 6 ~ 10 times of weight his cyclodextrin inclusion complex at double, add dried cream powder, magnesium stearate and microcrystalline Cellulose, mixing, makes granule, incapsulates, obtain capsule.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103611094A (en) * | 2013-12-12 | 2014-03-05 | 王学玲 | Medicament for treating cervical cancer |
Non-Patent Citations (3)
| Title |
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| 吴复苍: "《常见病遣方用药规律》", 31 October 2015, 中国医药科技出版社 * |
| 周绪堂: "《实用肿瘤诊疗手册》", 30 November 1997, 江西科学技术出版社 * |
| 李冈荣: "《汉方中草药对症图典 第4册》", 30 September 2015, 新疆科技卫生出版社 * |
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