CN104587376A - Drug for treating qi stagnation and blood stasis-type thoracic obstruction and preparation method of drug oral liquid - Google Patents

Drug for treating qi stagnation and blood stasis-type thoracic obstruction and preparation method of drug oral liquid Download PDF

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CN104587376A
CN104587376A CN201310526402.0A CN201310526402A CN104587376A CN 104587376 A CN104587376 A CN 104587376A CN 201310526402 A CN201310526402 A CN 201310526402A CN 104587376 A CN104587376 A CN 104587376A
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radix
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semen
stagnation
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邓生福
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Abstract

The invention discloses a drug for treating qi stagnation and blood stasis-type thoracic obstruction. The drug comprises, by weight, 30-80 parts of radix bupleuri, 1-20 parts of radix scutellariae, 25-50 parts of red sage root, 1-20 parts of green tangerine peel, 20-30 parts of radix curcumae, 20-50 parts of lily, 1-50 parts of rhizoma corydalis, 1-30 parts of faeces trogopterori, 20-30 parts of white peony root, 1-20 parts of semen brassicae, 1-10 parts of peach seed and 10-16 parts of snakegourd seed. The drug is used for treating thoracic obstruction pain and has substantial effects by promoting blood circulation to remove blood stasis and dredging blood vessel. The preparation method of an oral liquid containing the drug has simple processes. The leached oral liquid can be fast absorbed by the human body and produce effects fast. Through a condensation technology, an oral liquid dosage is reduced and the oral liquid is convenient for carrying, preservation and taking.

Description

A kind of medicine and oral liquor thereof for the treatment of the qi stagnation and blood stasis type thoracic obstruction
Technical field
The invention belongs to a kind of Chinese medicine composition, be specifically related to a kind of medicine and oral liquor thereof for the treatment of the qi stagnation and blood stasis type thoracic obstruction .
Background technology
The thoracic obstruction refers to suffocating pain over the chest, even chest pain radiating to the back, loses heart, a kind of disease that failing to sleep due to dyspnea is primary symptom, and the lighter only feels uncomfortable in chest as stopped up, and breathe and owe smooth, severe one then has chest pain, severe patient chest pain radiating to the back, backache radiating to the heart.Many and the inward invasion of pathogenic cold of the generation of primary disease, improper diet, disorder of emotion, the factors such as aged debility are relevant.Its pathogenesis has deficiency and excess two aspect: real is cold coagulation, the stagnation of QI, blood stasis, stagnation of phlegm, stagnated chest-YANG, stagnating heart meridian; Void is heart spleen caused by liver and kidney deficiency, and heart arteries and veins loses supports.This symptom is mainly in mid-aged population, also presents the trend of rejuvenation at present, and it is modal is exactly angina pectoris, Symptoms for having palpitation, breathing hard, dizzy etc.At present, the clinical medicine for the disease treatment of thoracic obstruction angina pectoris class of doctor trained in Western medicine, as nitroglycerin, persantin etc. mainly lay particular emphasis on the alleviation of acute symptom, still lack effective means to the treatment of the cause of disease, the toxic and side effects of its medicine is also larger.And in the current clinical practice of the traditional Chinese medical science, treat angina pectoris Chinese patent medicine used, as FUFANG DANSHEN PIAN, DANQI PIAN etc. also also exist the defect that medication is comprehensive, curative effect is low, onset is slow, therefore, therapeutic effect is unsatisfactory.
Oral liquid absorbs the process characteristic of Chinese medicine, by decoction refining, concentrated, embedding further, sterilizing and obtaining.Oral liquid is come across market, as Oral Liquid Radix Panacis Quinquefolii, Ferulic acid etc. with a kind of form of health product the earliest; And recently, many curative oral liquids emerge in multitude in the formulation, as YINHUANG KOUFUYE, antivirus oral liquid, QINGRE JIEDU KOUFUYE etc., and by increasing popular good, there is following advantage in oral liquid formulations, comprehensively can leach the plurality of health care functions composition in raw material, play the health care that it is comprehensive; Absorb fast, dose-effect is rapid; Can produce in enormous quantities, remove the trouble that consumer does it yourself to make from, taking convenience.
Summary of the invention
Large for prior art western medicines in treatment toxic and side effects, the problems such as Chinese medicine medication is not comprehensively, curative effect is low, onset is slow, the invention provides the medicine that a kind of production cost is low, evident in efficacy, treat the qi stagnation and blood stasis type thoracic obstruction, and technique simply prepares the method for this medicine oral liquid.
To achieve these goals, the technical solution used in the present invention is: a kind of medicine for the treatment of the qi stagnation and blood stasis type thoracic obstruction, and this Chinese medicine composition is made up of the crude drug of following weight portion:
Radix Bupleuri 30-80 part, Radix Scutellariae 1-20 part, Herba Wedeliae Wallichii 25-50 part, Pericarpium Citri Reticulatae Viride 1-20 part, Radix Curcumae 20-30 part, Bulbus Lilii 20-50 part, Rhizoma Corydalis 1-50 part, Oletum Trogopterori 1-30 part, Radix Paeoniae Alba 20-30 part, hundred Semen Sinapis 1-20 parts, Semen Persicae 1-10 part, Semen Trichosanthis 10-16 part.
The weight portion of each crude drug of described Chinese medicine composition is: Radix Bupleuri 45 parts, Radix Scutellariae 10 parts, Herba Wedeliae Wallichii 30 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 24 parts, Bulbus Lilii 30 parts, Rhizoma Corydalis 15 parts, Oletum Trogopterori 10 parts, the Radix Paeoniae Alba 30 parts, hundred 10 parts, Semen Sinapiss, 6 parts, Semen Persicae, Semen Trichosanthis 15 parts.
The oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction, concrete steps are as follows:
A, crude drug process, clean Radix Bupleuri, Radix Scutellariae, Herba Wedeliae Wallichii, Pericarpium Citri Reticulatae Viride, Radix Curcumae, Bulbus Lilii, Rhizoma Corydalis, the Radix Paeoniae Alba, hundred Semen Sinapiss and Semen Trichosanthis, dry, and reprocesses in flakes or section, Semen Persicae is milled into coarse powder;
B, lixiviate, add decoction pot by the crude drug of step a process and Oletum Trogopterori and carry out lixiviate, obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c carries out concentrating to obtain concentrated medicament, and concentrating degree is to daily measuring 30-60ml;
E, subpackage sterilizing, load in sterile chamber after the concentrated medicament of steps d is added antiseptic and seal, and then adopts flowing steam method to carry out sterilization treatment.
The lixiviate of described step b, extraction time crude drug and Oletum Trogopterori being added decoction pot is 1-3 hour, filters and merge to obtain medicine stock solution after decocting 2-4 time.
The concentrated of described steps d is that medicine stock solution is concentrated by backflow, obtains concentrated medicament.
The weight of each crude drug can with a gram calculating above.
In the present invention, the pharmacological property of each raw material is as follows:
Radix Bupleuri: bitter in the mouth, cold nature.Return liver, gallbladder meridian.Evacuation is had to bring down a fever, soothing liver-QI, the function of yang invigorating.For cold, fever, alternate attack of chill and fever, malaria, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, the diseases such as proctoptosis.Recent studies is used for treating influenza virus, tubercule bacillus, disease caused by plasmodium.
Radix Scutellariae: bitter, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Herba Wedeliae Wallichii: sweet, temperature.Enrich blood, invigorate blood circulation, eliminate-poverty blood, puerperal hemorrhea, hysteromyoma, amenorrhea, neurasthenia.
Pericarpium Citri Reticulatae Viride: slightly warm in nature, bitter in the mouth is pungent, enters liver, gallbladder meridian.Have effect of soothing the liver dispelling the stagnated QI, eliminating stagnation expectorant, soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.
Radix Curcumae: arduous, cool, enters the heart, lung, Liver Channel.Promoting QI circulation for relieving depression, removing heat from blood removing blood stasis with potent drugs.Control all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.
Bulbus Lilii: Bulbus Lilii sweet in the mouth, cold nature.GUIXIN, lung meridian.Pathogen precordial pain and distention of the abdomen, sharp defecation, invigorating the spleen and replenishing QI.Except edema cranium is swollen, breast interventral accumulated heat distension, overall pain, newborn tasty laryngopharynx swelling and pain, gulp down a mouthful saliva difficulty, only tears.Except diaphragm portion distending pain, control beriberi heat syndrome cough.Feel at ease, calm the nerves, beneficial will, support the five internal organs, control that insane heresy is mad cries palpitation with fear, the bruise that postpartum hemorrhage causes, schistosomicide, assist the various skin ulcers of carbuncle, acute mastitis carbuncle on the back swollen.Also Bulbus Lilii syndrome can be controlled, warming the lung antitussive
Rhizoma Corydalis: Rhizoma Corydalis acrid in the mouth, hardship, warm in nature.There is promoting blood circulation to remove blood stasis, the function of promoting the circulation of QI pain relieving.For whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
Oletum Trogopterori: sweet in flavor and warm in property, nontoxic, enter Liver Channel, there is dredging blood vessel, effect of eliminating stasis to stop pain; Can be used for blood-stasis internal-depression, escape of blood from meridian hemorrhage, if woman uterine bleeding is through many, the purple polylith of color, stabbing pain of the lower abdomen.
The Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Suitable: people's breast abdomen pain over the hypochondriac region of the blood deficiency deficiency of YIN, pain in the hepatic region, cholecystitis gallstones pain person should eat; Dysentery is suffered from abdominal pain, and women's menalgia person should eat; Spontaneous perspiration easy antiperspirant night sweat person should eat; Sural spasm, spasm of the limbs pain, uneasy lower limb syndrome patients should eat; Coordinate with alleviating various breast abdomen and limbs pain with Radix Glycyrrhizae.
Hundred Semen Sinapiss: warm in nature, acrid in the mouth.Enter lung, stomach two warp.Tool promoting the circulation of QI eliminating phlegm, the effect of reducing swelling and alleviating pain.Promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, removing obstruction in the collateral to relieve pain.Control phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain, regurgitation is vomitted, aphasia due to apoplexy, and limbs arthralgia pain is numb, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury.
Semen Persicae: bitter but sweet flavor is pungent is flat, nontoxic.Blood stasis removing and clots absorbing, moisturizes laxation.Control amenorrhea , mass in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
Semen Trichosanthis: feeble QI, sweet in the mouth, micro-bitterness.Removing heat-phlegm, the disease of scorching productive cough, promoting the circulation of QI the chest stuffiness relieving, for the thoracic obstruction, breast knot, eliminating carbuncle eliminating stagnation, for lung abscess, acute appendicitis, acute mastitis etc., bowel relieving relieving constipation, for dryness of the intestine constipation.
In the present invention, each medicine supplements and complements each other, and the mutual cooperation of various crude drug reaches medicine optimum curative effect.Radix Bupleuri, Radix Scutellariae, Pericarpium Citri Reticulatae Viride, Radix Curcumae, Bulbus Lilii, the Radix Paeoniae Alba, hundred Semen Sinapiss and Semen Trichosanthis, this a few taste medical instrument has the diseases such as treatment is uncomfortable in chest, all pains of distending pain in the chest and hypochondrium, breast abdomen side of body rib, the interventral accumulated heat distension of breast and limbs arthralgia pain are numb, this a few taste medical instrument of Herba Wedeliae Wallichii, Rhizoma Corydalis and Semen Persicae is invigorated blood circulation the curative effects such as QI invigorating, promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving, dredging blood vessel, Oletum Trogopterori has hemorrhage effect for the treatment of blood-stasis internal-depression, escape of blood from meridian, to sum up, the present invention, while treatment thoracic obstruction pain, reaches the remarkable result of the treatment qi stagnation and blood stasis type thoracic obstruction by blood circulation promoting and blood stasis dispelling and dredging blood vessel.
Oral liquor technique of the present invention is simple, and fast in absorption of human body through the oral liquid leached, dose-effect is rapid; By concentration technology, oral liquid dose reduces, and is easy to carry, preserves and takes; Oral liquid finished product, through sterilization treatment, packs, steady quality, not perishable; Oral liquid can be produced in enormous quantities, removes the trouble that consumer does it yourself to make from, taking convenience.
The present invention in clinical case 100 example, total effective rate 96%, cure rate 95.83%.
The present invention treats the routine clinical observation result of morbid leukorrhea 100:
1. clinical data: age 40-80 year.
2. administrated method: oral liquid, the morning, noon and afternoon service once, each one bottle, within 15 days, are a course for the treatment of.
3, therapeutic effect
(1) criterion of therapeutical effect
A. fully recover: symptom and sign disappears, do not recur after stopping using;
B. effective: symptom and sign disappears substantially.Comparatively the lighter is recurred after drug withdrawal.
C. invalid: to treat three months with clinical symptoms without improver.
(2) result: 92 examples of fully recovering (accounting for 90%), effective 4 examples (accounting for 6%), invalid 4 examples (accounting for 4%) total effective rate 96%.
Detailed description of the invention
embodiment 1:treat a medicine for the qi stagnation and blood stasis type thoracic obstruction, this Chinese medicine composition is made up of the crude drug of following weight portion:
Radix Bupleuri 30-80 part, Radix Scutellariae 1-20 part, Herba Wedeliae Wallichii 25-50 part, Pericarpium Citri Reticulatae Viride 1-20 part, Radix Curcumae 20-30 part, Bulbus Lilii 20-50 part, Rhizoma Corydalis 1-50 part, Oletum Trogopterori 1-30 part, Radix Paeoniae Alba 20-30 part, hundred Semen Sinapis 1-20 parts, Semen Persicae 1-10 part, Semen Trichosanthis 10-16 part.
The weight portion of each crude drug of Chinese medicine composition is: Radix Bupleuri 45 parts, Radix Scutellariae 10 parts, Herba Wedeliae Wallichii 30 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 24 parts, Bulbus Lilii 30 parts, Rhizoma Corydalis 15 parts, Oletum Trogopterori 10 parts, the Radix Paeoniae Alba 30 parts, hundred 10 parts, Semen Sinapiss, 6 parts, Semen Persicae, Semen Trichosanthis 15 parts.
The oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction, concrete steps are as follows:
A, crude drug process, clean Radix Bupleuri, Radix Scutellariae, Herba Wedeliae Wallichii, Pericarpium Citri Reticulatae Viride, Radix Curcumae, Bulbus Lilii, Rhizoma Corydalis, the Radix Paeoniae Alba, hundred Semen Sinapiss and Semen Trichosanthis, dry, and reprocesses in flakes or section, Semen Persicae is milled into coarse powder;
B, lixiviate, add decoction pot by the crude drug of step a process and Oletum Trogopterori and carry out lixiviate, obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c carries out concentrating to obtain concentrated medicament, and concentrating degree is to daily measuring 30-60ml;
E, subpackage sterilizing, load in sterile chamber after the concentrated medicament of steps d is added antiseptic and seal, and then adopts flowing steam method to carry out sterilization treatment.
The lixiviate of step b, extraction time raw material and Oletum Trogopterori being added decoction pot is 1-3 hour, filters and merge to obtain medicine stock solution after decocting 2-4 time.
The concentrated of steps d is that medicine stock solution is concentrated by backflow, obtains concentrated medicament.
embodiment 2:treat a medicine for the qi stagnation and blood stasis type thoracic obstruction, this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Radix Bupleuri 45 parts, Radix Scutellariae 10 parts, Herba Wedeliae Wallichii 30 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 24 parts, Bulbus Lilii 30 parts, Rhizoma Corydalis 15 parts, Oletum Trogopterori 10 parts, the Radix Paeoniae Alba 30 parts, hundred 10 parts, Semen Sinapiss, 6 parts, Semen Persicae, Semen Trichosanthis 15 parts.
The oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction, oral formulations is made with above-mentioned crude drug, concrete steps are as follows: a, raw material disposal, Radix Bupleuri 45 parts, Radix Scutellariae 10 parts, Herba Wedeliae Wallichii 30 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 24 parts, Bulbus Lilii 30 parts, Rhizoma Corydalis 15 parts, the Radix Paeoniae Alba 30 parts, 10 parts, hundred Semen Sinapis and Semen Trichosanthis 15 parts are cleaned, dries, reprocess in blocks or section, 6 parts, Semen Persicae is milled into coarse powder;
B, lixiviate, the crude drug of step a process and 10 parts of Oletum Trogopterori are added decoction pot and carries out lixiviate, extraction time is 3 hours, decocts to filter afterwards for 2 times to merge to obtain medicine stock solution;
C, purification, carry out purified treatment by the medicine stock solution of step b through microfilter;
D, concentrated, the medicinal liquid after being purified by step c carries out that backflow is concentrated to obtain concentrated medicament, and concentrating degree extremely daily measures 60ml;
E, subpackage sterilizing, load in sterile chamber after the concentrated medicament of steps d is added antiseptic and seal, and then adopts flowing steam method to carry out sterilization treatment.
Case 1: military certain, man, 41 years old, Yuan Kang town, Linzhou City of Henan Province Xihua people from village, suffocating pain over the chest, chest pain radiating to the back, losed heart, pants.Every natural gift morning, noon and afternoon take three deuterzooid oral liquids, the bottled amount of each 20ml, fully recover after taking 3 courses for the treatment of, from taking 1 year so far without recurrence.
embodiment 3:treat a medicine for the qi stagnation and blood stasis type thoracic obstruction, this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Radix Bupleuri 30 parts, Radix Scutellariae 1 part, Herba Wedeliae Wallichii 25 parts, 5 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 30 parts, Bulbus Lilii 20 parts, Rhizoma Corydalis 35 parts, Oletum Trogopterori 1 part, the Radix Paeoniae Alba 20 parts, hundred 1 part, Semen Sinapiss, 10 parts, Semen Persicae, Semen Trichosanthis 10 parts.
The oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction, oral formulations made by above raw material, concrete steps are as follows: a, raw material disposal, Radix Bupleuri 30 parts, Radix Scutellariae 1 part, Herba Wedeliae Wallichii 25 parts, 5 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 30 parts, Bulbus Lilii 20 parts, Rhizoma Corydalis 35 parts, the Radix Paeoniae Alba 20 parts, 1 part, hundred Semen Sinapis and Semen Trichosanthis 10 parts are cleaned, dries, reprocess in blocks or section, 10 parts, Semen Persicae is milled into coarse powder;
B, lixiviate, the raw material of step a process and 1 part of Oletum Trogopterori are added decoction pot and carries out lixiviate, extraction time is 1 hour, decocts to filter afterwards for 4 times to merge to obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c carries out that backflow is concentrated to obtain concentrated medicament, and concentrating degree extremely daily measures 60ml;
E, subpackage sterilizing, load in sterile chamber after the concentrated medicament of steps d is added antiseptic and seal, and then adopts flowing steam method to carry out sterilization treatment.
Case 2: Zhang, man, 53 years old, Yuan Kang town, Linzhou City of Henan Province Xihua people from village, suffocating pain over the chest, losed heart.Every natural gift morning, noon and afternoon take three deuterzooid oral liquids, the bottled amount of each 20ml, fully recover after taking 2 courses for the treatment of, without recurrence.
embodiment 4:treat a medicine for the qi stagnation and blood stasis type thoracic obstruction, this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Radix Bupleuri 80 parts, Radix Scutellariae 20 parts, Herba Wedeliae Wallichii 50 parts, 20 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 20 parts, Bulbus Lilii 50 parts, Rhizoma Corydalis 50 parts, Oletum Trogopterori 30 parts, the Radix Paeoniae Alba 20 parts, hundred 20 parts, Semen Sinapiss, 10 parts, Semen Persicae, Semen Trichosanthis 16 parts.
The oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction, oral formulations made by above raw material, concrete steps are as follows: a, raw material disposal, Radix Bupleuri 80 parts, Radix Scutellariae 20 parts, Herba Wedeliae Wallichii 50 parts, 20 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 20 parts, Bulbus Lilii 50 parts, Rhizoma Corydalis 50 parts, the Radix Paeoniae Alba 20 parts, 20 parts, hundred Semen Sinapis and Semen Trichosanthis 16 parts are cleaned, dries, reprocess in blocks or section, 10 parts, Semen Persicae is milled into coarse powder;
B, lixiviate, the raw material of step a process and 30 parts of Oletum Trogopterori are added decoction pot and carries out lixiviate, extraction time is 2 hours, decocts to filter afterwards for 4 times to merge to obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c carries out that backflow is concentrated to obtain concentrated medicament, and concentrating degree extremely daily measures 30ml;
E, subpackage sterilizing, load in sterile chamber after the concentrated medicament of steps d is added antiseptic and seal, and then adopts flowing steam method to carry out sterilization treatment.
Case 3: Liu, female, 80 years old, Yuan Kang town, Linzhou City of Henan Province Xihua people from village, suffocating pain over the chest, losed heart, pants.Take 4 courses for the treatment of of this oral liquid, recovery from illness.
embodiment 5:treat a medicine for the qi stagnation and blood stasis type thoracic obstruction, this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Radix Bupleuri 50 parts, Radix Scutellariae 16 parts, Herba Wedeliae Wallichii 40 parts, 8 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 27 parts, Bulbus Lilii 40 parts, Rhizoma Corydalis 30 parts, Oletum Trogopterori 25 parts, the Radix Paeoniae Alba 23 parts, hundred 13 parts, Semen Sinapiss, 4 parts, Semen Persicae, Semen Trichosanthis 12 parts.
The oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction, oral formulations made by above raw material, concrete steps are as follows: a, raw material disposal, Radix Bupleuri 50 parts, Radix Scutellariae 16 parts, Herba Wedeliae Wallichii 40 parts, 8 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 27 parts, Bulbus Lilii 40 parts, Rhizoma Corydalis 30 parts, the Radix Paeoniae Alba 23 parts, 13 parts, hundred Semen Sinapis and Semen Trichosanthis 12 parts are cleaned, dries, reprocess in blocks or section, 4 parts, Semen Persicae is milled into coarse powder;
B, lixiviate, the raw material of step a process and 25 parts of Oletum Trogopterori are added decoction pot and carries out lixiviate, extraction time is 1.5 hours, decocts to filter afterwards for 3 times to merge to obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c carries out that backflow is concentrated to obtain concentrated medicament, and concentrating degree extremely daily measures 30ml;
E, subpackage sterilizing, load in sterile chamber after the concentrated medicament of steps d is added antiseptic and seal, and then adopts flowing steam method to carry out sterilization treatment.
Case 4: Wang, man, 67 years old, Yuan Kang town, Linzhou City of Henan Province Xihua people from village, suffocating pain over the chest, chest pain radiating to the back, losed heart, pants.Take 4 courses for the treatment of of this oral liquid, recovery from illness.
embodiment 6:treat a medicine for the qi stagnation and blood stasis type thoracic obstruction, this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Radix Bupleuri 70 parts, Radix Scutellariae 18 parts, Herba Wedeliae Wallichii 35 parts, 14 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 26 parts, Bulbus Lilii 45 parts, Rhizoma Corydalis 29 parts, Oletum Trogopterori 25 parts, the Radix Paeoniae Alba 22 parts, hundred 9 parts, Semen Sinapiss, 8 parts, Semen Persicae, Semen Trichosanthis 11 parts.
The oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction, oral formulations made by above raw material, concrete steps are as follows: a, raw material disposal, Radix Bupleuri 70 parts, Radix Scutellariae 18 parts, Herba Wedeliae Wallichii 35 parts, 14 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 26 parts, Bulbus Lilii 45 parts, Rhizoma Corydalis 29 parts, the Radix Paeoniae Alba 22 parts, 9 parts, hundred Semen Sinapis and Semen Trichosanthis 11 parts are cleaned, dries, reprocess in blocks or section, 8 parts, Semen Persicae is milled into coarse powder;
B, lixiviate, the raw material of step a process and 25 parts of Oletum Trogopterori are added decoction pot and carries out lixiviate, extraction time is 2.5 hours, decocts to filter afterwards for 4 times to merge to obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c carries out that backflow is concentrated to obtain concentrated medicament, and concentrating degree extremely daily measures 45ml;
E, subpackage sterilizing, load in sterile chamber after the concentrated medicament of steps d is added antiseptic and seal, and adopts flowing steam method to carry out sterilization treatment.
Case 5: go into business certain, man, 35 years old, Yuan Kang town, Linzhou City of Henan Province Xihua people from village, suffocating pain over the chest, chest pain radiating to the back, losed heart, pants.Every natural gift morning, noon and afternoon take three deuterzooid oral liquids, the bottled amount of each 15ml, fully recover after taking 3 courses for the treatment of.

Claims (5)

1. treat a medicine for the qi stagnation and blood stasis type thoracic obstruction, it is characterized in that: this Chinese medicine composition is made up of the crude drug of following weight portion:
Radix Bupleuri 30-80 part, Radix Scutellariae 1-20 part, Herba Wedeliae Wallichii 25-50 part, Pericarpium Citri Reticulatae Viride 1-20 part, Radix Curcumae 20-30 part, Bulbus Lilii 20-50 part, Rhizoma Corydalis 1-50 part, Oletum Trogopterori 1-30 part, Radix Paeoniae Alba 20-30 part, hundred Semen Sinapis 1-20 parts, Semen Persicae 1-10 part, Semen Trichosanthis 10-16 part.
2. the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction according to claim 1, is characterized in that: the weight portion of each crude drug of described Chinese medicine composition is: Radix Bupleuri 45 parts, Radix Scutellariae 10 parts, Herba Wedeliae Wallichii 30 parts, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Curcumae 24 parts, Bulbus Lilii 30 parts, Rhizoma Corydalis 15 parts, Oletum Trogopterori 10 parts, the Radix Paeoniae Alba 30 parts, hundred 10 parts, Semen Sinapiss, 6 parts, Semen Persicae, Semen Trichosanthis 15 parts.
3. the oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction according to claim 1, is characterized in that: concrete steps are as follows:
A, crude drug process, clean Radix Bupleuri, Radix Scutellariae, Herba Wedeliae Wallichii, Pericarpium Citri Reticulatae Viride, Radix Curcumae, Bulbus Lilii, Rhizoma Corydalis, the Radix Paeoniae Alba, hundred Semen Sinapiss and Semen Trichosanthis, dry, and reprocesses in flakes or section, Semen Persicae is milled into coarse powder;
B, lixiviate, add decoction pot by the crude drug of step a process and Oletum Trogopterori and carry out lixiviate, obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c carries out concentrating to obtain concentrated medicament, and concentrating degree is to daily measuring 30-60ml;
E, subpackage sterilizing, load in sterile chamber after the concentrated medicament of steps d is added antiseptic and seal, and then adopts flowing steam method to carry out sterilization treatment.
4. the oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction according to claim 3, it is characterized in that: the lixiviate of described step b, extraction time crude drug and Oletum Trogopterori being added decoction pot is 1-3 hour, filters and merge to obtain medicine stock solution after decocting 2-4 time.
5. the oral liquor of the medicine of the treatment qi stagnation and blood stasis type thoracic obstruction according to claim 3, is characterized in that: the concentrated of described steps d is that medicine stock solution is concentrated by backflow, obtains concentrated medicament.
CN201310526402.0A 2013-10-31 2013-10-31 Drug for treating qi stagnation and blood stasis-type thoracic obstruction and preparation method of drug oral liquid Pending CN104587376A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822779A (en) * 2017-02-16 2017-06-13 成都富豪斯生物科技有限公司 A kind of Chinese medicine composition of the obstruction of qi in the chest and palpitation and insomnia for treating caused by energy stagnation and blood stasis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106822779A (en) * 2017-02-16 2017-06-13 成都富豪斯生物科技有限公司 A kind of Chinese medicine composition of the obstruction of qi in the chest and palpitation and insomnia for treating caused by energy stagnation and blood stasis

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