CN105596277A - Cactus face cream for treating acne and preparation method thereof - Google Patents

Abstract

The invention discloses cactus face cream for treating acne and a preparation method thereof. The face cream comprises terbinafine hydrochloride, cactus, radix zanthoxyli, herba portulacae, aloe, blueberry, radix glycyrrhizae preparata, carmine radish, pomegranate bark, herba taraxaci, chamomile essential oil, sandalwood essential oil, pearl, polyvinyl alcohol and glycerinum. The preparation method includes material preparation, juicing, extraction of active ingredients of raw traditional Chinese medicinal materials and preparation of the face cream. The face cream is proper in compatibility of the raw medicinal materials, mild and effective, and is capable of effectively treating acne, as well as whitening and moistening the skin, reducing chloasma and scar, resisting to oxidation, promoting skin metabolism, enhancing vascular and skin elasticity, promoting blood circulation, improving skin smoothness, suppressing inflammation and irritability and heightening skin resistance.

Description

A kind of cactus face cream and preparation method of Acne treatment

Technical field

The invention belongs to medicine adornment field, is a kind of cactus face cream and preparation method of Acne treatment concretely.

Background technology

Acne claims again whelk, and main and hypersteatosis, pilosebaceous duct stop up, bacterium infectsClosely related with factors such as inflammatory reactions. After adolescing in human body androgen particularly the level of testosterone is fastSpeed raises, and promotes sebaceous glands grow and produce a large amount of sebums. The dyskeratosis of pilosebaceous duct is made simultaneouslyBecome conduit to stop up, dyssebacia, forming horn plug is micro mist thorn. In hair follicle, multiple-microorganism especiallyPropionibacterium acnes amount reproduction, the lipase that propionibacterium acnes produces decomposes sebum and generates free fatty,Chemotactic inflammatory cell and medium simultaneously, final induction exacerbate inflammation reaction. Acne lesions be apt to occur in face andUpper chest and back, shows as acne, inflammatory papule, and the infringements such as secondary pustule, tubercle, often accompany seborrhea.Easily form pigmentation, the thick even scar of pore etc. and leave over illness, the psychology to patient and life cause tightHeavy impact. Face cream on market mostly only has the effect of moisturizing moisturizing or nourishes rough skin, to acne skin withoutMethod plays result for the treatment of targetedly.

Summary of the invention

For effective Acne treatment, the invention provides a kind of cactus face cream and preparation method of Acne treatment,Not only effective Acne treatment of face cream of the present invention, can also whitening, skin care, desalination color spot, scar,Anti-oxidant, promotion skin metabolism, strengthen blood vessel and skin elasticity, stimulates circulation and promote skinSmoothness, inflammation-inhibiting and allergy, increase skin resistance.

The present invention seeks to be realized by following technical scheme:

A cactus face cream for Acne treatment, its component and parts by weight comprise: terbinafine HCl 2～5Part, 60～65 parts, cactus, 45～50 parts of Radix zanthoxylis, 30～35 parts of purslanes, 40～45 parts of aloes, indigo plant35～40 parts of the certain kind of berries, 35～40 parts of honey-fried licorice roots, 35～40 parts of rouge radish, 40～45 parts of granatums, dandelion 25～30Part, 15～20 parts of chamomile essential oils, 10～20 parts of santal essential oils, 35～40 parts of pearls, 25～30 parts of polyvinyl alcohol,30～35 parts of glycerine.

The object of the invention can also be realized by following technical scheme:

A cactus face cream for Acne treatment, its component and parts by weight comprise: 2 parts of terbinafine HCls,60 parts, cactus, 45 parts of Radix zanthoxylis, 30 parts of purslanes, 40 parts of aloes, 35 parts of blueberries, 35 parts of honey-fried licorice roots,35 parts of rouge radish, 40 parts of granatums, 25 parts of dandelions, 15 parts of chamomile essential oils, 10 parts of santal essential oils,35 parts of pearls, 25 parts of polyvinyl alcohol, 30 parts of glycerine.

A cactus face cream for Acne treatment, its component and parts by weight comprise: 5 parts of terbinafine HCls,65 parts, cactus, 50 parts of Radix zanthoxylis, 35 parts of purslanes, 45 parts of aloes, 40 parts of blueberries, 40 parts of honey-fried licorice roots,40 parts of rouge radish, 45 parts of granatums, 30 parts of dandelions, 20 parts of chamomile essential oils, 20 parts of santal essential oils,40 parts of pearls, 30 parts of polyvinyl alcohol, 35 parts of glycerine.

A cactus face cream for Acne treatment, its component and parts by weight comprise: 3 parts of terbinafine HCls,62 parts, cactus, 48 parts of Radix zanthoxylis, 33 parts of purslanes, 42 parts of aloes, 37 parts of blueberries, 39 parts of honey-fried licorice roots,36 parts of rouge radish, 43 parts of granatums, 27 parts of dandelions, 18 parts of chamomile essential oils, 16 parts of santal essential oils,38 parts of pearls, 29 parts of polyvinyl alcohol, 34 parts of glycerine.

The present invention also provides a kind of preparation method of cactus face cream of Acne treatment, comprises the steps:

1) get the raw materials ready, get the raw materials ready according to component and the parts by weight of the cactus face cream of described a kind of Acne treatment,Wherein crushing pearl is crossed 800 mesh sieves;

2) squeeze the juice, fresh cactus, aloe, blueberry, rouge radish were pulverized to 20 mesh sieves, add 10 timesThe deionized water of parts by weight is soaked 12h, crosses elimination filter residue, and filtrate is for subsequent use;

3) extraction of Chinese medicine material pharmaceutically active ingredient, by step 2) gained filtrate adds in Chinese medicine extracting tank,Open and stir, Chinese medicine material medicine Radix zanthoxyli, purslane, honey-fried licorice root, granatum, dandelion are added to Chinese medicineIn extractor, the temperature of charge in Chinese medicine extracting tank is warming up to 90～100 DEG C of constant temperature 1h, crosses leaching filtrate,Filtrate Vacuum Concentration to thick, when its relative density is 40 DEG C 1.21～1.28, is cooled to room temperature for subsequent use;

4) preparation of face cream, mixes polyvinyl alcohol, glycerine, is heated to 55～60 DEG C, to mixtureMiddle order adds terbinafine HCl, step 3) gained concentrate, step 1) gained pearl powder, chamomileEssential oil, santal essential oil, stir, and is cooled to room temperature packing for subsequent use.

The preparation method of the cactus face cream of a kind of Acne treatment of the present invention, can also be by following technical schemeRealize:

Described step 3) Vacuum Concentration condition is: vacuum is-0.07～-0.08MPa, and temperature is 40～45 DEG C.

For effective Acne treatment, the present invention, through a large amount of screening tests, screens Chinese and Western bulk drug,Take the method for clearing heat and cooling blood, bactericidal antiphlogistic, swelling and pain relieving, Shu Min myogenic, improve illing skin, killSuppress pathogenic bacteria, promote acne wound healing, effectively prophylactic treatment face acnes. All bulk drugs, compatibility phaseSuitable, effectively gentle, specifically, in the bulk drug of choosing:

Terbinafine HCl, is propylamine antifungal, in Antifungi cell ergosterol building-up processMF59 Cycloxygenase, and MF59 is accumulated in cell and rise bactericidal action. Human body cell is to the special ratio of hydrochloric acidNaphthalene sweet smell sensitiveness be fungi ten thousand/. There is broad-spectrum antifungal effect, dermatophyte is had to sterilizationEffect, plays bacteriostasis to Candida albicans. Be applicable to skin, nail infection that superficial fungi causes,The ringworm of the body that causes as trichophyta, dog sporidiole bacteria, acrothesium floccosum etc., jock itch, tinea pedis, onychomycosis andSkin candida albicans infection. Terbinafine HCl disturbs the biosynthetic early stage step of mycosterol specifically,The shortage and the squalene that cause thus ergosterol gather intracellular, thereby cause fungal cell's death.Terbinafine HCl plays a role by the squalene epoxidase on Antifungi cell membrane. This product is only usedIn treatment large area, serious (ringworm of the body, jock itch, tinea pedis, favus of the scalp) and candida albicans (ferment as false in whiteFemale) the skin yeast infection that causes, that considers oral administration according to infection site, seriousness and scope mustThe property wanted.

Cactus, cold in nature, bitter, enters the heart, lung, stomach three warps; The promoting flow of qi and blood circulation, clearing heat and detoxicating. Control heart stomachGas pain, lump in the abdomen, dysentery, hemorrhoid blood, cough, laryngalgia, lung carbuncle, acute mastitis, furunculosis, burn, snakebite.Cactus is a kind of multi-functional plant, 18 seed amino acids and the various trace elements that contain needed by human,As all very high in the content of VB1, VB2, carrotene, potassium, calcium etc., and contain and can strengthen human immunityThe compositions such as the Baobi lotus of ability. There are heat reliving and toxin-eliminating, stomach invigorating moistening lung, the promoting flow of qi and blood circulation, anti-bacteria, beauty treatment to protectSkin and anti-aging effects.

Radix zanthoxyli, bitter, pungent, property is flat returns liver, stomach warp, promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain, dispelling wind and removing obstruction in the meridians, separatesPoison detumescence.

Purslane, cold in nature, the sweet acid of taste, enters the heart, liver, spleen, large intestine channel, has that hygroscopic is antipruritic, heat-clearing disappearsSwollen, clearing heat and detoxicating, Li Shui dries, loose blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, the effect of the cool blood that stops blooding.Purslane has stronger inhibitory action to shigella dysenteriae, typhoid bacillus and Escherichia coli, can be used for various inflammationSupplemental treatment, have the title of " natural antibiotics ", purslane is also rich in vitamin C, vitamin C simultaneouslyHaving good antioxidation can whitening nourishes rough skin, and modern medicine finds, purslane has higher battalionSupport and be worth and medical value, except containing the nutrients such as conventional proteins,vitamins,and minerals,Purslane also contains unique bioactive ingredients, can strengthen the activity of Human Epithelial Cells, contributes to urgeEnter ulcer and must heal.

Aloe: purging intense heat, removing toxic substances, stagnation resolvation, desinsection, argument is red, constipation, gonorrhoea, hematuria, pediatric epilepsy scared,Infantile malnutrition due to digestive disturbances or intestinalparasites, burn and scald, women's amenorrhoea, hemorrhoid, scabies, carbuncle furuncle poison, traumatic injury, the mucus in aloe(mucin is exactly protein), be taking the polysaccharides such as arboranABaloemannanaloetin asNucleus, mucus class material is the important component that prevents cell senescence and treatment chronic allergic, mucoitin is depositedThe muscle and the gastrointestinal mucosa etc. that are human body are located, and allow and organize high resilience, if liquid element is not enough, muscle and stickyFilm will have been lost elasticity and be stiff aging, Aloin A, wound hormone and glycan peptide sweet dew (Ke-2) etc.There is viral infection resisting, promote the effect that wound healing is restored, have anti-inflammation and sterilization, heat absorption detumescence, softening skinSkin, keep the function of cell viability, curdlan to combine with traumatic acid also thering is healing wounds activity.

Blueberry, contains abundant nutritional labeling in fruit, have that the cranial nerve of preventing is aging, a vision protection, strongThe functions such as the heart, anticancer, softening blood vessel, enhancing human organism immunity, nutritional labeling is high, and blueberry is rich in anthocyanidinGlucoside is a kind of strong antioxidant, and it can protect human body to avoid the damage of free radical, and anthocyanidin glucoside alsoCan strengthen blood vessel elasticity, improve the smoothness of blood circulation system and enhancement skin, inflammation-inhibiting and allergy,Vitamin C in blueberry is one of antioxidant vitamins, can effectively remove free radical, prevents skin senescence.

Honey-fried licorice root, contains the number of chemical compositions such as glycyrrhizin, enoxolone, licorice polysaccharide, has anti-inflammatoryAnd anti-allergy action, adjustable body's immunity, antitumor and analgesic effect. Therefore honey-fried licorice rootMain effect is and middle emergency that moistening lung, detoxifies, coordinating the drug actions of a prescription. Be usually used in weakness of the spleen and the stomach, lassitude hypodynamia,Severe palpilation, intermittent pulse, can separate monkshood poison.

Rouge radish, radish is cool in nature, taste is pungent, sweet, have stagnant, the reducing phlegm and fever of disappearing, lower gas wide in, separateEffect of poison, can enhance metabolism, improves a poor appetite, help digest, and can eliminate indigestion stagnant, often eating radish canReduce blood fat, softening blood vessel, stabilizing blood pressure, can prevent coronary heart disease, artery sclerosis, cholelithiasis and other diseases,Rouge radish, except having the effect of common radish, is also rich in anthocyanidin and anthocyanin, and anthocyanidin is a kind of strongStrong antioxidant, it can protect human body to avoid the damage of free radical, and anthocyanidin can also strengthen blood vesselElasticity, smoothness, inflammation-inhibiting and the allergy improving blood circulation system and promote skin.

Granatum, convergence, antibacterial. In vitro test has Pseudomonas aeruginosa, bacterium flexneri, typhoid bacillusAntibacterial action, also has inhibitory action in various degree to various skin fungi, also has resisiting influenza virus effect.

Dandelion, cold in nature, bitter, sweet; Return liver, stomach warp; Clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia,Be mainly used in treating furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen,Heat is drenched puckery pain.

Chamomile essential oil, can improve acne, allergy, eczema, burn and scald, can say pure to skin the bestOne of reveal, there is anti-inflammatory and pacify characteristic, for responsive and face sore skin, to dryness, the sensitive utmost pointGood, treatment pimples, bleb, eczema, tinea, capilary are broken and have good effect, can be used for protectingThe eye skin that face is the most responsive, remarkable for treatment face sore and red seal effect, increase skin resistance.

Santal essential oil, is applicable to aging, dry and lack of water skin, can desalinate scar, microgroove, Glycerin,Prevention wrinkle, can effectively prevent acne scar acne to print and produce.

Pearl, the arresting convulsion of calming the nerves, heat-clearing enriching yin, improving eyesight, removing toxic substances. Convergence myogenic, be applicable to throat rot,Aphthae, ulcer do not close up for a long time, should external application. Suppress lipofuscin, removing free radical, antitumor, desalinationFreckle, chloasma. Modern medicine study is also found, contains a large amount of trace elements in pearl, have anti-oxidant,Strengthen the effects such as skin activity, heat-clearing toxin expelling, but also there is whitening, myogenic, anti-acne, control oil, desalinationThe effects such as color spot. Meanwhile, by the function of its clean in addition clean deep skin, because pearl powder has very strongAdsorption capacity, so the dirt of pore deep layer can clean under the suction-operated of pearl powder. Control the inferiorIt is rotten that infantile malnutrition due to digestive disturbances or intestinalparasites skin damages meat, and unbearably, and the new meat of all sores is full for the pain utmost point, can not rawhide, and soup sprinkles and burns skin to damage meat rotten again,Gnawing pains take no rest; Can, by human epidermal Cell uptake, strengthen cell viability, function enhances metabolism. AgainBecause they contain higher aliphatic etc., thereby there is skin care effect.

Face cream of the present invention, in preparation process, adopts modern advanced medical pharmaceutical technology, fully extracts formerMaterial pharmaceutically active ingredient, selected all medicines: terbinafine HCl bactericidal antiphlogistic can effect a radical cure acne, cactus is cold in nature,Bitter, enters the heart, lung, stomach three warps; The promoting flow of qi and blood circulation, clearing heat and detoxicating. And contain and can strengthen human immunityThe compositions such as the Baobi lotus of ability. There are heat reliving and toxin-eliminating, stomach invigorating moistening lung, the promoting flow of qi and blood circulation, anti-bacteria, beauty treatment to protectSkin and anti-aging effects. Radix zanthoxyli bitter, pungent, property is flat returns liver, stomach warp, promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain,Dispelling wind and removing obstruction in the meridians, removing toxicity for detumescence. Pearl, the arresting convulsion of calming the nerves, heat-clearing enriching yin, improving eyesight, removing toxic substances. Convergence myogenic,Suppress lipofuscin, remove free radical, antitumor, desalination freckle, chloasma. There is anti-oxidant, enhancing skinThe effects such as activity, heat-clearing toxin expelling, but also there is whitening, myogenic, anti-acne, control oil, desalination color spot, cleanThe effects such as face. Above terbinafine HCl, cactus, Radix zanthoxyli, pearl are monarch drug in a prescription altogether, and tool is played sterilization and disappearedInflammation, antipruritic, bitterly, clearing heat and detoxicating, convergence myogenic, desalination scar, effect of color spot and whitening, mainly usesIn Acne treatment. In addition, cactus, Radix zanthoxyli are promoting blood circulation and removing blood stasis, can also promote the absorption of other drug. HorseBitterroot, cold in nature, the sweet acid of taste, enters the heart, liver, spleen, large intestine channel, has that hygroscopic is antipruritic, a clearing heat for detumescence, clearThermal detoxification, Li Shui dries, loose blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, the effect of the cool blood that stops blooding. Aloe:Purging intense heat, removing toxic substances, stagnation resolvation, desinsection, argument is red, constipation, gonorrhoea, hematuria, pediatric epilepsy scared, infantile malnutrition due to digestive disturbances or intestinalparasites, burnsScald women's amenorrhoea, hemorrhoid, scabies, carbuncle furuncle poison, traumatic injury. Granatum, convergence, antibacterial.In vitro test has antibacterial action to Pseudomonas aeruginosa, bacterium flexneri, typhoid bacillus, to various skin fungiAlso there is inhibitory action in various degree, also have resisiting influenza virus effect. Dandelion, cold in nature, bitter, sweet;Return liver, stomach warp; Clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia, is mainly used in treating furuncle swelling toxin, acute mastitis,Scrofula, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen, heat is drenched puckery pain. Above purslane, aloe,Granatum, dandelion are ministerial drug altogether, auxiliary monarch drug in a prescription bactericidal antiphlogistic, heat-clearing toxin expelling, antipruritic. Blueberry, fruitIn contain abundant nutritional labeling, have that the cranial nerve of preventing is aging, a vision protection, cardiac stimulant, anticancer, softeningThe functions such as blood vessel, enhancing human organism immunity, chamomile essential oil, can improve acne, allergy, eczema, burningScald, can say one of best hydrosol of skin, there is anti-inflammatory and pacify characteristic, for responsive and face sore skinSkin, fabulous to dryness, sensitive, to treatment pimples, bleb, eczema, tinea, capilary breaks hasGood effect, can be used for protecting the most responsive eye skin of face, for treatment face sore and red seal effectSignificantly, increase skin resistance. Santal essential oil, is applicable to aging, dry and lack of water skin, can desalinate scar,Microgroove, Glycerin, prevention wrinkle, can effectively prevent acne scar acne to print and produce. Rouge radish, radish is cool in nature,Taste is pungent, sweet, have stagnant, the reducing phlegm and fever of disappearing, lower gas wide in, effect of removing toxic substances, can enhance metabolism.Above blueberry, chamomile essential oil, santal essential oil are adjutant altogether, can improve scar, color spot that acne stays,And can improve immunity, promote the treatment of acne. Honey-fried licorice root, for making medicine, has anti-inflammatory and antiallergic actionEffect, adjustable body's immunity, antitumor and analgesic effect. Therefore main effect of honey-fried licorice root be withMiddle emergency, moistening lung, removing toxic substances, coordinating the drug actions of a prescription.

In addition, purslane is also rich in vitamin C, and vitamin C has good antioxidation and can whitening growSupport skin, the mucous class material of aloe institute is the important component that prevents cell senescence and treatment chronic allergic, gluesLiquid element is present in muscle and the gastrointestinal mucosa etc. of human body to be located, and allows and organizes high resilience. Blueberry is rich in anthocyanidin glucosideBe a kind of strong antioxidant, it can protect human body to avoid the damage of free radical, and anthocyanidin glucoside can alsoEnough strengthen blood vessel elasticity, improve the smoothness of blood circulation system and enhancement skin, inflammation-inhibiting and allergy,Vitamin C in blueberry is one of antioxidant vitamins, can effectively remove free radical, prevents skin senescence.Rouge radish is also rich in anthocyanidin and anthocyanin, and anthocyanidin is a kind of strong antioxidant, and it can be protectedProtect human body and avoid the damage of free radical, anthocyanidin can also strengthen blood vessel elasticity, improve blood circulation system andPromote the smoothness of skin, inflammation-inhibiting and allergy, increase skin resistance.

Auxiliary material polyvinyl alcohol used, glycerine have effect anticorrosion, moisturizing, not only can improve after making face creamThe use term of validity of face cream can also be together with other medicines skin care.

Beneficial effect of the present invention

For effective Acne treatment, the present invention, through a large amount of screening tests, screens Chinese and Western bulk drug,Take the method for clearing heat and cooling blood, bactericidal antiphlogistic, swelling and pain relieving, Shu Min myogenic, improve illing skin, killSuppress pathogenic bacteria, promote acne wound healing, effectively prophylactic treatment face acnes. All bulk drug compatibilities are suitable,Gentle effectively not only effective Acne treatment, can also whitening, skin care, and desalination color spot, scar, resistOxidation, promote to strengthen blood vessel and skin elasticity by skin metabolism, stimulate circulation and promote skinSmoothness, inflammation-inhibiting and allergy, increase skin resistance. Technique of the present invention is simple, and the term of validity is grown, joinedFang Heli, without drug dependence, toxic and side effect is little, cheap, is applicable to suitability for industrialized production.

Detailed description of the invention

According to following embodiment, the present invention may be better understood. But those skilled in the art is easyUnderstand, the described concrete material proportion of embodiment, process conditions and result thereof are only for illustrating the present inventionAnd should can not limit the present invention described in detail in claims yet.

Embodiment 1

A cactus face cream for Acne treatment, its component and parts by weight comprise: 2 parts of terbinafine HCls,60 parts, cactus, 45 parts of Radix zanthoxylis, 30 parts of purslanes, 40 parts of aloes, 35 parts of blueberries, honey-fried licorice root 35Part, 35 parts of rouge radish, 40 parts of granatums, 25 parts of dandelions, 15 parts of chamomile essential oils, santal essence10 parts of oil, 35 parts of pearls, 25 parts of polyvinyl alcohol, 30 parts of glycerine.

A preparation method for the cactus face cream of Acne treatment, comprises the steps:

1) get the raw materials ready, get the raw materials ready according to component and the parts by weight of the cactus face cream of described a kind of Acne treatment,Wherein crushing pearl is crossed 800 mesh sieves;

2) squeeze the juice, fresh cactus, aloe, blueberry, rouge radish were pulverized to 20 mesh sieves, add 10 timesThe deionized water of parts by weight is soaked 12h, crosses elimination filter residue, and filtrate is for subsequent use;

3) extraction of Chinese medicine material pharmaceutically active ingredient, by step 2) gained filtrate adds in Chinese medicine extracting tank,Open and stir, Chinese medicine material medicine Radix zanthoxyli, purslane, honey-fried licorice root, granatum, dandelion are added to Chinese medicineIn extractor, the temperature of charge in Chinese medicine extracting tank is warming up to 90 DEG C of constant temperature 1h, crosses leaching filtrate, will filterLiquid Vacuum Concentration is to thick, when its relative density is 40 DEG C 1.21～1.28, is cooled to room temperature for subsequent use; VacuumConcentrated condition is: vacuum is-0.07～-0.08MPa, and temperature is 40～45 DEG C;

4) preparation of face cream, mixes polyvinyl alcohol, glycerine, is heated to 55～60 DEG C, to mixtureMiddle order adds terbinafine HCl, step 3) gained concentrate, step 1) gained pearl powder, chamomileEssential oil, santal essential oil, stir, and is cooled to room temperature packing for subsequent use.

Using method: sooner or later clean every day and get face cream of the present invention after face and be evenly applied in face.

Embodiment 2

A cactus face cream for Acne treatment, its component and parts by weight comprise: 5 parts of terbinafine HCls,65 parts, cactus, 50 parts of Radix zanthoxylis, 35 parts of purslanes, 45 parts of aloes, 40 parts of blueberries, 40 parts of honey-fried licorice roots,40 parts of rouge radish, 45 parts of granatums, 30 parts of dandelions, 20 parts of chamomile essential oils, 20 parts of santal essential oils,40 parts of pearls, 30 parts of polyvinyl alcohol, 35 parts of glycerine.

A preparation method for the cactus face cream of Acne treatment, comprises the steps:

1) get the raw materials ready, get the raw materials ready according to component and the parts by weight of the cactus face cream of described a kind of Acne treatment,Wherein crushing pearl is crossed 800 mesh sieves;

2) squeeze the juice, fresh cactus, aloe, blueberry, rouge radish were pulverized to 20 mesh sieves, add 10 timesThe deionized water of parts by weight is soaked 12h, crosses elimination filter residue, and filtrate is for subsequent use;

3) extraction of Chinese medicine material pharmaceutically active ingredient, by step 2) gained filtrate adds in Chinese medicine extracting tank,Open and stir, Chinese medicine material medicine Radix zanthoxyli, purslane, honey-fried licorice root, granatum, dandelion are added to Chinese medicineIn extractor, the temperature of charge in Chinese medicine extracting tank is warming up to 95 DEG C of constant temperature 1h, crosses leaching filtrate, will filterLiquid Vacuum Concentration is to thick, when its relative density is 40 DEG C 1.21～1.28, is cooled to room temperature for subsequent use; VacuumConcentrated condition is: vacuum is-0.07～-0.08MPa, and temperature is 40～45 DEG C;

4) preparation of face cream, mixes polyvinyl alcohol, glycerine, is heated to 55～60 DEG C, to mixtureMiddle order adds terbinafine HCl, step 3) gained concentrate, step 1) gained pearl powder, chamomileEssential oil, santal essential oil, stir, and is cooled to room temperature packing for subsequent use.

Using method: sooner or later clean every day and get face cream of the present invention after face and be evenly applied in face.

Embodiment 3

A cactus face cream for Acne treatment, its component and parts by weight comprise: 3 parts of terbinafine HCls,62 parts, cactus, 48 parts of Radix zanthoxylis, 33 parts of purslanes, 42 parts of aloes, 37 parts of blueberries, honey-fried licorice root 39Part, 36 parts of rouge radish, 43 parts of granatums, 27 parts of dandelions, 18 parts of chamomile essential oils, santal essence16 parts of oil, 38 parts of pearls, 29 parts of polyvinyl alcohol, 34 parts of glycerine.

A preparation method for the cactus face cream of Acne treatment, comprises the steps:

1) get the raw materials ready, get the raw materials ready according to component and the parts by weight of the cactus face cream of described a kind of Acne treatment,Wherein crushing pearl is crossed 800 mesh sieves;

2) squeeze the juice, fresh cactus, aloe, blueberry, rouge radish were pulverized to 20 mesh sieves, add 10 timesThe deionized water of parts by weight is soaked 12h, crosses elimination filter residue, and filtrate is for subsequent use;

3) extraction of Chinese medicine material pharmaceutically active ingredient, by step 2) gained filtrate adds in Chinese medicine extracting tank,Open and stir, Chinese medicine material medicine Radix zanthoxyli, purslane, honey-fried licorice root, granatum, dandelion are added to Chinese medicineIn extractor, the temperature of charge in Chinese medicine extracting tank is warming up to 100 DEG C of constant temperature 1h, crosses leaching filtrate, will filterLiquid Vacuum Concentration is to thick, when its relative density is 40 DEG C 1.21～1.28, is cooled to room temperature for subsequent use; VacuumConcentrated condition is: vacuum is-0.07～-0.08MPa, and temperature is 40～45 DEG C;

4) preparation of face cream, mixes polyvinyl alcohol, glycerine, is heated to 55～60 DEG C, to mixtureMiddle order adds terbinafine HCl, step 3) gained concentrate, step 1) gained pearl powder, chamomileEssential oil, santal essential oil, stir, and is cooled to room temperature packing for subsequent use.

Using method: sooner or later clean every day and get face cream of the present invention after face and be evenly applied in face.

Embodiment 4

Hypersensitive test

Get 18 of healthy albino guinea-pigs, body weight 250-300g, male and female dual-purpose, rejects both sides dorsal body setae before test,Every side 3 × 3cm, is divided into test group, blank group and positive controls at random; Positive controls is with 2,4-dinitrofluorobenzene, sensitization 1% concentration, excites and uses 0.1% concentration; The embodiment of the present invention 3 for test groupPreparation cactus face cream. Get face cream prepared by the embodiment of the present invention 3 and be applied to unhairing district, back, the next day 1Inferior, totally 3 times. Contact latter 14 days in last, smear this face cream at back the same area, after 6h, remove medicineAfter product, at once observe, and in 24,48,72h observes and has or not allergic reaction. Blank group and positive controlGroup uses same method excite contact and observe. Result of the test: positive controls animal skin in sensitization after 1 hour isOccur localized erythema and slight oedema, within 24 hours, symptoms of allergic increases the weight of, and sensitization rate is 100%, examinationTest group and blank treated animal skin and all do not occur any symptoms of allergic, sensitization rate is 0%. Experiment knotFruit shows that face cream formula of the present invention is gentle non-stimulated.

Embodiment 5

Transdermal absorption checks

Reference substance is Terbinafine hydrochloride emulsifiable paste, and trial target is the cactus face cream making with embodiment 1, with pureWater purification dissolves control sample, test specimen respectively.

This inspection method with skin is: mouse skin after processing.

This inspection method with instrument is: Transdermal absorption test instrument does Transdermal absorption test, measures by HPLCMedicine transit dose. Test method: " Chinese pharmacopoeia " 2010 version (two) is about transdermal patch releaseAssay method, all in 0.5h, 1h, 2h, 4h sampling. Terbinafine HCl absorptivity (%) result of the testSee the following form.

Interpretation of result: as can be seen from the test results, face cream Transdermal absorption better effects if of the present invention, testThe transdermal absorption factor of sample 2h is similar with the transdermal absorption factor of reference substance 4h; When test specimen 4h, transdermal is inhaledReceive substantially complete.

Embodiment 6

Application Example

The face cream of the embodiment of the present invention 1 to 3 is on probation through 100 face acnes patients respectively, and wherein, man altogether177 people, female is totally 123 people, age 14-40 year. Using method is: experimenter directly uses and is subject to trial product,Every day is each use once sooner or later, after clean face, directly will be subject to trial product to be evenly applied to face, adheres to makingWith three months, check the effect of face cream Acne treatment of the present invention. The evaluation criterion of curative effect is:

Recovery from illness: face acnes skin damages healing, the healing surface of a wound prints and produces without acne scar, acne;

Effective: face acnes reduces, or surface of a wound redness alleviates;

Invalid: the unchanged or aggravation of illness.

Statistics is as follows:

	Embodiment 1	Embodiment 2	Embodiment 3
				Recovery from illness	27	37	35
Effective	68	60	63
				Invalid	5	3	2
Efficient	95	97	98

Experimental result can find out, the efficient of face cream of the present invention reaches more than 95%, and all patients are usingStage is all without bad reaction such as allergic grade.

Model case:

Lin, female, 32 years old, face acnes patient, acne is mainly in cheek, is multiple hoary hair's acne,Medical history 1 year, is used the Chinese medicine Pimple removing scream of the embodiment of the present invention 1 after 1 month, and facial hoary hair's acne are obviousReduce, continue to use 5 months, face acnes recovery from illness, prints and produces without acne scar, acne, and rear 1 year without recurrence.

Liu, female, 14 years old, facial acne nodosum was associated with part blackhead, used the invention processThe Chinese medicine Pimple removing scream of example 2 is after 2 months, and blackhead all disappears, and face acnes alleviates, and continues to use 1Individual month, patient's recovery from illness, printed and produces without acne scar, acne, and rear 1 year without recurrence.

Xue, man, 45 years old, face acnes patient, acne is mainly in forehead and cheek, is multiple hoary hairAcne, medical history 3 years, outbreak repeatedly, is used the Chinese medicine Pimple removing scream of the embodiment of the present invention 3 after 1 month,Face acnes obviously reduces, and redness alleviates, and continues to use 6 months, and face acnes recovery from illness, without acne scar, acnePrint and produce, rear 1 year without recurrence.

Above embodiment is only explanation technical conceive of the present invention and feature, and its object is to allow is familiar with thisThe people of technology understands content of the present invention and is implemented, and can not limit the scope of the invention with this, allThe equivalence that Spirit Essence does according to the present invention changes or modifies, and all should be encompassed in protection scope of the present invention.

Claims (6)

1. a cactus face cream for Acne treatment, is characterized in that, its component and parts by weight comprise: salt2～5 parts of acid Terbinafines, 60～65 parts, cactus, 45～50 parts of Radix zanthoxylis, 30～35 parts of purslanes, aloe 40～45Part, 35～40 parts of blueberries, 35～40 parts of honey-fried licorice roots, 35～40 parts of rouge radish, 40～45 parts of granatums, Pu Gong25～30 parts of English, 15～20 parts of chamomile essential oils, 10～20 parts of santal essential oils, 35～40 parts of pearls, polyvinyl alcohol30～35 parts of 25～30 parts, glycerine.

2. the cactus face cream of a kind of Acne treatment according to claim 1, is characterized in that, its groupPoint and parts by weight comprise: 2 parts of terbinafine HCls, 60 parts, cactus, 45 parts of Radix zanthoxylis, 30 parts of purslanes,40 parts of aloes, 35 parts of blueberries, 35 parts of honey-fried licorice roots, 35 parts of rouge radish, 40 parts of granatums, 25 parts of dandelions,15 parts of chamomile essential oils, 10 parts of santal essential oils, 35 parts of pearls, 25 parts of polyvinyl alcohol, 30 parts of glycerine.

3. the cactus face cream of a kind of Acne treatment according to claim 1, is characterized in that, its groupPoint and parts by weight comprise: 5 parts of terbinafine HCls, 65 parts, cactus, 50 parts of Radix zanthoxylis, 35 parts of purslanes,45 parts of aloes, 40 parts of blueberries, 40 parts of honey-fried licorice roots, 40 parts of rouge radish, 45 parts of granatums, 30 parts of dandelions,20 parts of chamomile essential oils, 20 parts of santal essential oils, 40 parts of pearls, 30 parts of polyvinyl alcohol, 35 parts of glycerine.

4. the cactus face cream of a kind of Acne treatment according to claim 1, is characterized in that, its groupPoint and parts by weight comprise: 3 parts of terbinafine HCls, 62 parts, cactus, 48 parts of Radix zanthoxylis, 33 parts of purslanes,42 parts of aloes, 37 parts of blueberries, 39 parts of honey-fried licorice roots, 36 parts of rouge radish, 43 parts of granatums, 27 parts of dandelions,18 parts of chamomile essential oils, 16 parts of santal essential oils, 38 parts of pearls, 29 parts of polyvinyl alcohol, 34 parts of glycerine.

5. a preparation method for the cactus face cream of Acne treatment, is characterized in that, comprises the steps:

1) get the raw materials ready, according to the group of the cactus face cream of a kind of Acne treatment described in claim 1～4 any onePoint and parts by weight get the raw materials ready, wherein crushing pearl is crossed 800 mesh sieves;

2) squeeze the juice, fresh cactus, aloe, blueberry, rouge radish were pulverized to 20 mesh sieves, add 10 timesThe deionized water of parts by weight is soaked 12h, crosses elimination filter residue, and filtrate is for subsequent use;

3) extraction of Chinese medicine material pharmaceutically active ingredient, by step 2) gained filtrate adds in Chinese medicine extracting tank,Open and stir, Chinese medicine material medicine Radix zanthoxyli, purslane, honey-fried licorice root, granatum, dandelion are added to Chinese medicineIn extractor, the temperature of charge in Chinese medicine extracting tank is warming up to 90～100 DEG C of constant temperature 1h, crosses leaching filtrate,Filtrate Vacuum Concentration to thick, when its relative density is 40 DEG C 1.21～1.28, is cooled to room temperature for subsequent use;

4) preparation of face cream, mixes polyvinyl alcohol, glycerine, is heated to 55～60 DEG C, to mixtureMiddle order adds terbinafine HCl, step 3) gained concentrate, step 1) gained pearl powder, chamomileEssential oil, santal essential oil, stir, and is cooled to room temperature packing for subsequent use.

6. the preparation method of the cactus face cream of a kind of Acne treatment according to claim 5, its featureBeing described step 3) Vacuum Concentration condition is: vacuum is-0.07～-0.08MPa, and temperature is 40～45 DEG C.