CN105579044A - 双脱水半乳糖醇及其类似物与衍生物用于治疗复发性恶性神经胶瘤或进行性继发脑瘤的用途 - Google Patents

双脱水半乳糖醇及其类似物与衍生物用于治疗复发性恶性神经胶瘤或进行性继发脑瘤的用途 Download PDF

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Publication number
CN105579044A
CN105579044A CN201480042784.2A CN201480042784A CN105579044A CN 105579044 A CN105579044 A CN 105579044A CN 201480042784 A CN201480042784 A CN 201480042784A CN 105579044 A CN105579044 A CN 105579044A
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combination
inhibitors
group
derivatives
hexitol
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Chinese (zh)
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D·M·布朗
K·C·施
A·斯坦斯
R·施瓦兹
S·肯纳卡
H·A·伯三世
J·帕夏
W·加纳
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Del Mar Pharmaceuticals
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Del Mar Pharmaceuticals
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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CN201480042784.2A 2013-05-31 2014-06-02 双脱水半乳糖醇及其类似物与衍生物用于治疗复发性恶性神经胶瘤或进行性继发脑瘤的用途 Pending CN105579044A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361829739P 2013-05-31 2013-05-31
US61/829,739 2013-05-31
PCT/US2014/040461 WO2014194312A2 (en) 2013-05-31 2014-06-02 Use of dianhydrogalactitol and analogs and derivatives thereof to treat recurrent malignant glioma or progressive secondary brian tumor

Publications (1)

Publication Number Publication Date
CN105579044A true CN105579044A (zh) 2016-05-11

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CN201480042784.2A Pending CN105579044A (zh) 2013-05-31 2014-06-02 双脱水半乳糖醇及其类似物与衍生物用于治疗复发性恶性神经胶瘤或进行性继发脑瘤的用途

Country Status (14)

Country Link
US (1) US11026914B2 (enExample)
EP (1) EP3003321A4 (enExample)
JP (3) JP2016520622A (enExample)
KR (4) KR20160065776A (enExample)
CN (1) CN105579044A (enExample)
AU (2) AU2014273911B2 (enExample)
BR (1) BR112015029989A2 (enExample)
CA (1) CA2914025C (enExample)
CL (1) CL2015003512A1 (enExample)
IL (1) IL242853B (enExample)
MX (1) MX382824B (enExample)
SG (1) SG11201509837QA (enExample)
TW (1) TW201536278A (enExample)
WO (1) WO2014194312A2 (enExample)

Cited By (3)

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CN109337884A (zh) * 2018-12-21 2019-02-15 中国农业科学院北京畜牧兽医研究所 一种丙酮酸激酶基因及其应用
CN111328280A (zh) * 2017-09-11 2020-06-23 阿托萨治疗学公司 制备和使用内昔芬的方法
US12201591B2 (en) 2019-07-03 2025-01-21 Atossa Therapeutics, Inc. Sustained release compositions of endoxifen

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WO2014179528A2 (en) * 2013-05-01 2014-11-06 Brown Dennis M Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted naphthalimides such as amonafide for the treatment of immunological, metabolic, infectious, and benign or neoplastic hyperproliferative disease conditions
WO2015109391A1 (en) 2014-01-24 2015-07-30 Children's Hospital Of Eastern Ontario Research Institute Inc. Smc combination therapy for the treatment of cancer
WO2016138542A1 (en) * 2015-02-28 2016-09-01 Cyprus Therapeutics, Inc. Methods for inhibiting tumors and drug resistance
WO2017042634A2 (en) * 2015-09-10 2017-03-16 Del Mar Pharmaceuticals Use of dianhydrogalactitol or derivatives and analogs thereof for treatment of non-small-cell lung carcinoma, glioblastoma, and ovarian carcinoma by induction of dna damage and stalling of cell cycle
WO2017117202A1 (en) * 2015-12-29 2017-07-06 Oncobiologics, Inc. Buffered formulations of bevacizumab
US20200062839A1 (en) * 2017-05-01 2020-02-27 Del Mar Pharmaceuticals (Bc) Ltd. Use of dianhydrogalactitol or analogs and derivatives in combination with vegf inhibitors to treat cancer
US10624869B2 (en) 2017-05-08 2020-04-21 Stanislaw R. Burzynski Methods for the treatment of recurrent glioblastoma (RGBM)
US20180353446A1 (en) * 2017-06-07 2018-12-13 Ranedis Pharmaceuticals, Llc Compositions and methods of treating and/or preventing cancer
US11344521B2 (en) 2017-06-12 2022-05-31 Burzynski Research Institute, Inc. Methods for the treatment of leptomeningeal disease
IL272422B2 (en) * 2017-06-12 2025-03-01 R Burzynski Stanislaw Methods for the treatment of leptomeningeal disease
WO2019211708A1 (en) * 2018-05-04 2019-11-07 Kashiv Biosciences, Llc Stable pharmaceutical compositions of dianhydrogalactitol
KR102415193B1 (ko) 2020-04-16 2022-06-29 사회복지법인 삼성생명공익재단 벤즈브로마론을 유효성분으로 포함하는 뇌암 예방 또는 치료용 약학 조성물
WO2021252432A1 (en) * 2020-06-08 2021-12-16 Neonc Technologies, Inc. Compositions and methods for delivering polynucleotides
CN114796522A (zh) * 2022-01-06 2022-07-29 宁波大学 一种靶向线粒体放大氧化应激的新型抗肿瘤纳米药物
WO2024039764A2 (en) * 2022-08-17 2024-02-22 Ohio State Innovation Foundation Epitranscriptomic analysis of glioma
KR20250052523A (ko) 2023-10-11 2025-04-21 서울대학교병원 재발성 뇌 종양 진단, 예방 또는 치료에서의 cxcr-4의 용도

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111328280A (zh) * 2017-09-11 2020-06-23 阿托萨治疗学公司 制备和使用内昔芬的方法
US11572334B2 (en) 2017-09-11 2023-02-07 Atossa Therapeutics, Inc. Methods for making and using endoxifen
US11680036B1 (en) 2017-09-11 2023-06-20 Atossa Therapeutics, Inc. Methods for making and using endoxifen
US12071391B2 (en) 2017-09-11 2024-08-27 Atossa Therapeutics, Inc. Methods for making and using endoxifen
US12275684B2 (en) 2017-09-11 2025-04-15 Atossa Therapeutics, Inc. Methods for making and using endoxifen
US12281056B2 (en) 2017-09-11 2025-04-22 Atossa Therapeutics, Inc. Methods for making and using endoxifen
US12479790B2 (en) 2017-09-11 2025-11-25 Atossa Therapeutics, Inc. Methods for making and using endoxifen
CN109337884A (zh) * 2018-12-21 2019-02-15 中国农业科学院北京畜牧兽医研究所 一种丙酮酸激酶基因及其应用
CN109337884B (zh) * 2018-12-21 2021-09-17 中国农业科学院北京畜牧兽医研究所 一种丙酮酸激酶基因及其应用
CN109337884B9 (zh) * 2018-12-21 2021-10-29 中国农业科学院北京畜牧兽医研究所 一种丙酮酸激酶基因及其应用
US12201591B2 (en) 2019-07-03 2025-01-21 Atossa Therapeutics, Inc. Sustained release compositions of endoxifen

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JP2022088616A (ja) 2022-06-14
IL242853B (en) 2022-03-01
KR20160065776A (ko) 2016-06-09
KR20210100754A (ko) 2021-08-17
CA2914025A1 (en) 2014-12-04
KR20220080199A (ko) 2022-06-14
EP3003321A4 (en) 2017-01-18
JP2020079259A (ja) 2020-05-28
JP2016520622A (ja) 2016-07-14
WO2014194312A2 (en) 2014-12-04
MX2015016404A (es) 2016-09-28
SG11201509837QA (en) 2015-12-30
US11026914B2 (en) 2021-06-08
AU2014273911B2 (en) 2019-09-19
US20160158186A1 (en) 2016-06-09
TW201536278A (zh) 2015-10-01
MX382824B (es) 2025-03-13
AU2019283893B2 (en) 2022-03-24
CL2015003512A1 (es) 2016-09-09
BR112015029989A2 (pt) 2017-08-22
EP3003321A2 (en) 2016-04-13
CA2914025C (en) 2023-03-07
WO2014194312A3 (en) 2015-02-05
AU2019283893A1 (en) 2020-01-23
KR20230124765A (ko) 2023-08-25
AU2014273911A1 (en) 2016-01-07

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