CN1055630C - 三七丹参片及其制备方法 - Google Patents
三七丹参片及其制备方法 Download PDFInfo
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- CN1055630C CN1055630C CN96113176A CN96113176A CN1055630C CN 1055630 C CN1055630 C CN 1055630C CN 96113176 A CN96113176 A CN 96113176A CN 96113176 A CN96113176 A CN 96113176A CN 1055630 C CN1055630 C CN 1055630C
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- rhizoma cyperi
- ethanol
- notoginseng
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- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 244000131316 Panax pseudoginseng Species 0.000 title abstract 4
- 235000003181 Panax pseudoginseng Nutrition 0.000 title abstract 4
- 241000304195 Salvia miltiorrhiza Species 0.000 title abstract 3
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 title abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000000843 powder Substances 0.000 claims abstract description 26
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 15
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 15
- 239000012535 impurity Substances 0.000 claims abstract description 11
- 229920002472 Starch Polymers 0.000 claims abstract description 10
- 235000019698 starch Nutrition 0.000 claims abstract description 10
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- 229920001353 Dextrin Polymers 0.000 claims abstract description 9
- 239000004375 Dextrin Substances 0.000 claims abstract description 9
- 235000019425 dextrin Nutrition 0.000 claims abstract description 9
- 238000010992 reflux Methods 0.000 claims abstract description 6
- 239000000284 extract Substances 0.000 claims description 16
- 238000000605 extraction Methods 0.000 claims description 10
- 235000002020 sage Nutrition 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
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- 210000001035 gastrointestinal tract Anatomy 0.000 abstract description 4
- 206010002383 Angina Pectoris Diseases 0.000 abstract description 3
- 230000007812 deficiency Effects 0.000 abstract description 3
- 206010008479 Chest Pain Diseases 0.000 abstract description 2
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 210000002216 heart Anatomy 0.000 abstract description 2
- 230000010016 myocardial function Effects 0.000 abstract description 2
- 230000008506 pathogenesis Effects 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
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- 208000006083 Hypokinesia Diseases 0.000 abstract 1
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- 231100000957 no side effect Toxicity 0.000 abstract 1
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- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical class C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 1
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Abstract
本发明是一种三七丹参片,其特征在于含三七15-25%,丹参55-65%,香附15-25%,及淀粉、糊精适量。将三七、香附弃杂质碾粉备用;将丹参洗净,入提取罐,用95%加热回流提取3小时,滤取醇提取液至回收罐,入蒸发锅中80℃烘干,碾粉,与三七、香附粉及淀粉混均,制压成片。本发明的三七丹参片配方独到,切合病机;其制备方法得当,使药效发挥充分,具有活血化瘀,辅益心气,改善心肌功能的作用,对于冠心病,心绞痛,胸痛,气短,这乏力,气虚,血瘀者有较好疗效。并且对胃肠道无刺激,无副作用。
Description
本发明涉及药品生产技术领域,具体地说是三七丹参片及其制备方法。
目前对于治疗冠心病的药物主要有复方丹参片和山海丹。此类药物对冠心病有一定的疗效,但因其内含有冰片类物质,而此类药物对胃肠道有刺激等付作用。
本发明的目的是提供一种疗效好,又对胃肠道无刺激付作用的三七丹参片及其制备方法。
本发明是这样实现的:三七丹参片的组成为:三七15-25%,丹参55-65%,香附15-25%,及淀粉、糊精适量。
上述药片的制备方法是:将15-25%的三七、15-25%的香附弃杂质碾粉备用;将55-65%的丹参弃杂质冲洗净,入提取罐,加浓度为95%的乙醇浸过药面,加热回流提取3小时,滤取醇提取液至回收罐,药渣再加入95%的乙醇重复以上提取二次,合并醇提取液回收醇液,药渣再加水浸过药面,加热至沸2小时,过滤,将水提液与醇提物放入蒸发锅中80℃烘干,碾粉,与三七、香附粉混均,必要时加少量淀粉和糊精,制压成片。用淀粉和糊精主要是工艺上的需要,以补充粉剂的不足。
以下结合实施例对本发明作进一步的详述。
实施例1:
用20克三七、20克香附弃杂质碾粉备用;将60克丹参弃杂质冲洗净,入提取罐,加浓度为95%的乙醇浸过药面,加热至80℃回流提取3小时,滤取醇提取液至回收罐。药渣可重复提取一次,提取后可合并于提取液中,回收溶剂。然后将提取液放入蒸发锅中,将水份蒸干,再移至烘箱中80℃烘干,碾粉,与三七、香附粉及淀粉和糊精混均,制压成片。
实施例2:
用18克三七、18克香附弃杂质碾粉备用;将65克丹参弃杂质冲洗净,入提取罐,加浓度为95%的乙醇浸过药面,加热至80℃回流提取3小时,滤取醇提取液至回收罐。药渣可重复提取一次,提取后可合并于提取液中。然后将提取液放入蒸发锅中,将水份蒸干,再移至烘箱中80℃烘干,碾粉,与三七、香附粉及淀粉和糊精混均,制压成片。
实施例3,用22克三七,22克香附,55克丹参,按上述制备方法制得药片。
本发明的三七丹参片配方独到,切合病机;其制备方法得当,使药效发挥充分,具有活血化瘀,辅益心气,改善心肌功能的作用,对于冠心病,心绞痛,胸痛,气短,这乏力,气虚,血瘀者有较好疗效。并且对胃肠道无刺激,无附作用。本发明的三七丹参片疗效确切,作用持久,使用方便,安全可靠,长期服用对患者的心、肺、肝、肾未见不良反映,是治疗冠心病、心肌缺血、心绞痛理想的药物。
Claims (2)
1、一种三七丹参片,其特征在于其组成为三七15-25%,丹参55-65%,香附15-25%,及淀粉、糊精适量;将三七、香附弃杂质碾粉备用;将丹参弃杂质冲洗净,入提取罐,加浓度为95%的乙醇浸过药面,加热回流提取3小时,滤取醇提取液至回收罐,药渣再加入95%的乙醇重复以上提取二次,合并醇提取液回收醇液,药渣再加水浸过药面,加热至沸2小时,过滤,将水提液与醇提物放入蒸发锅中80℃烘干,碾粉,与三七、香附粉及淀粉和糊精混均,制压成片。
2、一种三七丹参片的制备方法,其特征在于将15-25%的三七、15-25%的香附弃杂质碾粉备用;将55-65%的丹参弃杂质冲洗净,入提取罐,加浓度为95%的乙醇浸过药面,加热回流提取3小时,滤取醇提取液至回收罐,药渣再加入95%的乙醇重复以上提取二次,合并醇提取液回收醇液,药渣再加水浸过药面,加热至沸2小时,过滤,将水提液与醇提物放入蒸发锅中80℃烘干,碾粉,与三七、香附粉及适量淀粉和糊精混均,制压成片。
Priority Applications (1)
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CN96113176A CN1055630C (zh) | 1996-10-25 | 1996-10-25 | 三七丹参片及其制备方法 |
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CN96113176A CN1055630C (zh) | 1996-10-25 | 1996-10-25 | 三七丹参片及其制备方法 |
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CN1151887A CN1151887A (zh) | 1997-06-18 |
CN1055630C true CN1055630C (zh) | 2000-08-23 |
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CN96113176A Expired - Lifetime CN1055630C (zh) | 1996-10-25 | 1996-10-25 | 三七丹参片及其制备方法 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8486464B2 (en) * | 2000-12-22 | 2013-07-16 | Tasly Pharmaceutical Group Co. Ltd. | Herbal composition for angina pectoris, method to prepare same and uses thereof |
US8883228B2 (en) | 2003-07-31 | 2014-11-11 | Tasly Pharmaceutical Group Co. Ltd. | Composition for heart disease, its active ingredients, method to prepare same and uses thereof |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1135996C (zh) * | 2000-06-09 | 2004-01-28 | 红桃开集团股份有限公司 | 一种治疗冠心病、心绞痛的中药及其制备方法 |
CN103385968A (zh) * | 2013-07-19 | 2013-11-13 | 苏州市天灵中药饮片有限公司 | 一种包含三七粉的中药及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1030183A (zh) * | 1987-06-30 | 1989-01-11 | 马德林 | 一种防治冠心病外用药的制作方法 |
CN1110584A (zh) * | 1994-12-17 | 1995-10-25 | 吴秀民 | 一种消炎宁中药 |
-
1996
- 1996-10-25 CN CN96113176A patent/CN1055630C/zh not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1030183A (zh) * | 1987-06-30 | 1989-01-11 | 马德林 | 一种防治冠心病外用药的制作方法 |
CN1110584A (zh) * | 1994-12-17 | 1995-10-25 | 吴秀民 | 一种消炎宁中药 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8486464B2 (en) * | 2000-12-22 | 2013-07-16 | Tasly Pharmaceutical Group Co. Ltd. | Herbal composition for angina pectoris, method to prepare same and uses thereof |
US8883228B2 (en) | 2003-07-31 | 2014-11-11 | Tasly Pharmaceutical Group Co. Ltd. | Composition for heart disease, its active ingredients, method to prepare same and uses thereof |
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Publication number | Publication date |
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CN1151887A (zh) | 1997-06-18 |
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