CN105560735A - Composition for treating dysfunctional uterine bleeding and preparation method thereof - Google Patents
Composition for treating dysfunctional uterine bleeding and preparation method thereof Download PDFInfo
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- CN105560735A CN105560735A CN201610063132.8A CN201610063132A CN105560735A CN 105560735 A CN105560735 A CN 105560735A CN 201610063132 A CN201610063132 A CN 201610063132A CN 105560735 A CN105560735 A CN 105560735A
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- uterine bleeding
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- dysfunctional uterine
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Abstract
The invention provides a composition for treating dysfunctional uterine bleeding. The composition is mainly prepared from, by weight, 4.5-9 parts of cornu cervi pantotrichum, 4.5-9 parts of herba ecliptae, 3-6 parts of rhizoma dioscoreae, 3-6 parts of apples, 3-6 parts of galla chinensis, 4.5-9 parts of sanchi, 0.9-1.5 parts of bombyx batryticatus, 9-30 parts of Japanese thistle herb roots, 9-12 parts of rhizoma cimicifugae, 6-12 parts of fructus ligustri lucidi, 6-12 parts of dried human placenta, 4-9 parts of radix paeoniae rubra, 3-12 parts of carapax et plastrum testudinis, 40-50 parts of honey and 200-400 parts of aromatic vinegar. The composition is remarkable in effect when used for treating dysfunctional uterine bleeding and functional uterine bleeding, has the bacteriostasis and haemostasis functions and can further thoroughly treat dysfunctional uterine bleeding from the root.
Description
Technical field
The invention discloses a kind of compositions, especially treat the composition and method of making the same of dysfunctional uterine bleeding.Belong to traditional Chinese medicine field.
Background technology
Dysfunctional uterine bleeding is called for short anovulatory dysfunctional uterine hemorrhage, refers to and is caused by neuroendocrine disorders, instead of caused by the whole bodies such as gestation, endometrial tumors, infection or hematopathy or female genital tract organic disease.Often betide adolescence or climacteric, mostly be anovulation type dysfunctional uterine bleeding.
Clinical manifestation: 1. metrorrhagia at random, few time many during blood volume, or increase suddenly.Amenorrhea time elder, amount of bleeding is many, and the sustainable several months is more than.Cycle is shorter than 21 days, time stream time only.2. health check-up edeoscopy is normal, or the slight increase in bilateral ovaries symmetry ground.3. basal body temperature is unipolar type.4. severe loss of blood can cause anemia, and severe patient can occur dizziness, has palpitation, breathes hard, weak, the phenomenon such as edema, inappetence.
The cause of disease: the reason causing anovulatory functional bleeding is different with climacteric in adolescence.Adolescent Dysfunctional is many reaches maturity incomplete due to hypothalamic-pituitary-ovarian axis or postpones, perfect feed-back regulatory mechanism is not yet set up between Hypothalamus-pituitary and ovary, under the effect of hypophysis follicle stimulating hormone (FSH) and lutropin (LH), follicular development secretion estrogen, but oestrogens on hypothalamic positive feedback still should can not form FSH and LH peak in normal menstrual cycle, though thus have follicular development not ovulate in ovary.Patients with Perimenopause Dysfunctional Uterine Bleeding is mainly due to ovarian function dieback, and follicle quantity reduces and dysmaturity, and reduce pituitary gonadotropic hormone reaction, thus when ovarian failure, ovulation stops and causing climacteric androgen-induced sterile rats simultaneously.Cause the reason of ovulation type anovulatory dysfunctional uterine hemorrhage to mainly contain: 1. have follicular development and ovulation in inadequate luteal function menstrual cycle, but the not enough or corpus luteum of Progesterone Secretion luteal phase fail too early, causes endometrial secretion bad.2. irregular shedding of endometrium is namely because atrophy of corpus iuteum is incomplete, and estrogen and progestogen can not decline rapidly, irregular shedding of endometrium, and the hemorrhage phase is extended, and blood volume increases, incomplete also known as atrophy of corpus iuteum.3. endometrium reparation extends due to after menstrual endometrium strips off, and the new follicular development of next cycle is slow or not good enough, secreted oestrogen deficiencies, so that endometrium can not Regeneration and Repair as scheduled, and menstruation is extended.4. ovulation bleeding is due to the of short duration decline of the hormone onset of ovulation, and make endometrium lose the support of hormone and occur that parton Endometrium comes off and cause withdrawal bleeding, when estrogen secretion q.s, then inner membrance is repaired again and stops blooding.
In the method for existing Chinese medicine dysfunctional uterine bleeding, Authorization Notice No. CN101703614B(application number 200910230042.3) patent discloses a kind of Chinese medicine decoction for the treatment of dysfunctional uterine bleeding, it is characterized in that being made up of the raw material of Chinese medicine of following parts by weight: the Radix Astragali 40 parts, Rhizoma Cimicifugae 15 parts, 30 parts, the Radix Rehmanniae, Radix Angelicae Sinensis 15 parts, Radix Salviae Miltiorrhizae 15 parts, Herba Leonuri 20 parts, Radix Bupleuri 15 parts, 20 parts, Colla Corii Asini and Endoconcha Sepiae 30 parts.Authorization Notice No. CN103263555B(application number 201310212688.5) patent discloses a kind of medicine for the treatment of dysfunctional uterine bleeding, it is characterized in that: it is made up of the crude drug in following weight range: Radix Codonopsis 10-15 gram, Radix Astragali 10-15 gram, Radix Scutellariae 10-15 gram, Cortex Phellodendri 15-20 gram, Radix Rehmanniae 10-20 gram, Radix Paeoniae Alba 8-12 gram, Flos Sophorae 8-12 gram, Radix Sanguisorbae 10-15 gram, Pollen Typhae 10-20 gram, Rhizoma Cyperi 8-12 gram, Carapax et Plastrum Testudinis 8-12 gram, Cortex Ailanthi 10-20 gram, Fructus Mume 10-20 gram, Radix Artemisia ordosicae 8-12 gram, Fibra Trachycarpi 10-20 gram, Radix Angelicae Sinensis 10-15 gram, Concha Ostreae 8-12 gram, Os Draconis 8-12 gram, Colla Corii Asini 6-10 gram, Cortex Lycii 8-12 gram, Flos Chrysanthemi 8-12 gram, Radix Rehmanniae Preparata 8-12 gram, Radix Panacis Quinquefolii 10-15 gram, Radix Glycyrrhizae 8-12 gram, Rhizoma Atractylodis Macrocephalae 10-15 gram, Poria 10-20 gram, Fructus Corni 10-20 gram, Cortex Eucommiae 10-20 gram, Radix Polygalae 10-20 gram, Fructus Schisandrae Chinensis 10-16 gram, Cortex Moutan 8-12 gram, Radix Bupleuri 10-15 gram, Herba Ecliptae 8-16 gram, Radix Berchemiae Yunnanensis 12-20 gram, Herba Commelinae 12-20 gram, Cortex Phellodendri 8-10 gram.Prepare burden expensive and be not easy to obtain, preparation method is complicated, and it is pill for oral administration, lotion and so on, cures the symptoms, not the disease, cannot reach the object of radical cure, be not suitable for long-term taking.
Summary of the invention
For the present situation of existing treatment dysfunctional uterine bleeding deficiency, an object of the present invention is to provide a kind of compositions for the treatment of dysfunctional uterine bleeding, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned treatment dysfunctional uterine bleeding.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a compositions for dysfunctional uterine bleeding, take off the primary raw material stating weight proportion and be prepared from: Cornu Cervi Pantotrichum 4.5-9 part, Herba Ecliptae 4.5-9 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 3-6 part, Fructus Mali pumilae 3-6 part, Galla Chinensis 3-6 part, Radix Notoginseng 4.5-9 part, Bombyx Batryticatus 0.9-1.5 part, cirsii japonici,radix 9-30 part is (preferred, cirsii japonici,radix 9.5-29.5 part), Rhizoma Cimicifugae 9-12 part, Fructus Ligustri Lucidi 6-12 part, Placenta Hominis 6-12 part, Radix Paeoniae Rubra 4-9 part, Carapax et Plastrum Testudinis 3-12 part, Mel 40-50 part, aromatic vinegar 200-400 part.
Treat a compositions for dysfunctional uterine bleeding, preferred proportioning, take off the primary raw material stating weight proportion and be prepared from: Cornu Cervi Pantotrichum 5-8 part, Herba Ecliptae 5-8 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 3.5-5 part, Fructus Mali pumilae 3.5-5 part, Galla Chinensis 3.5-5 part, Radix Notoginseng 5-8 part, Bombyx Batryticatus 1.0-1.4 part, cirsii japonici,radix 12-25 part, Rhizoma Cimicifugae 9.5-11 part, Fructus Ligustri Lucidi 7-11 part, Placenta Hominis 7-11 part, Radix Paeoniae Rubra 5-8 part, Carapax et Plastrum Testudinis 4-10 part, Mel 43-48 part, aromatic vinegar 250-350 part.
Treat a compositions for dysfunctional uterine bleeding, more preferably proportioning, take off the primary raw material stating weight proportion and be prepared from: 7 parts, Cornu Cervi Pantotrichum, Herba Ecliptae 7 parts, RHIIZOMA DIOSCOREAE fr0m Henan of China 4 parts, Fructus Mali pumilae 4 parts, Galla Chinensis 4 parts, Radix Notoginseng 6 parts, Bombyx Batryticatus 1.2 parts, cirsii japonici,radix 20 parts, Rhizoma Cimicifugae 10 parts, Fructus Ligustri Lucidi 9 parts, Placenta Hominis 8 parts, Radix Paeoniae Rubra 6 parts, Carapax et Plastrum Testudinis 6 parts, Mel 45 parts, aromatic vinegar 300 parts.
Treat a preparation method of composition for dysfunctional uterine bleeding, preparation process is as follows:
1. Carapax et Plastrum Testudinis is cleaned up to be fired to and be popular in, drop in decoction of black soybean and cool, take out and grind to form smalls to cross 80-120 mesh sieve stand-by;
2. RHIIZOMA DIOSCOREAE fr0m Henan of China and Fructus Mali pumilae are cleaned up, chopping, is placed in the interior white sugar of clean plate and mixes thoroughly, be placed on food steamer and steam 20-40 minute, be rolled into smalls with ferrum spoon, be placed on iron plate and smoke 3-8 minute, dry in the air cool stand-by;
3. Bombyx Batryticatus light salt brine is soaked 10-20 minute, it is crisp to take out parch, and it is stand-by to grind to form smalls;
4. Cornu Cervi Pantotrichum, Herba Ecliptae, Galla Chinensis, Radix Notoginseng, cirsii japonici,radix, Rhizoma Cimicifugae, Fructus Ligustri Lucidi, Placenta Hominis and Radix Paeoniae Rubra are together cleaned up, chopping, scalds 2-6 time with boiling hot deep fat, dries in the air to crisp, grind to form smalls, crosses 120-160 mesh sieve stand-by;
5. aromatic vinegar is placed in container, slow fire boiling is to boiling, Mel is added after 2-6 minute until boiling, be stirred to rapidly and melt completely, add 1.-4. gains, after stirring, add clear water dilution, the consumption of water is 1-2 times of aromatic vinegar weight, cover lid decocts 13-18 minute slowly, and cross 200-240 order drainage screen, filtrate is bottled and obtained compositions.
Above-mentioned preparation method, 1. step is taken out and is ground to form smalls and cross 90-110 mesh sieve stand-by (preferably take out grind to form smalls cross 100 mesh sieves stand-by).
Above-mentioned preparation method, 2. step is placed on food steamer and steams 25-35 minute, is rolled into smalls with ferrum spoon, is placed on iron plate and smokes 4-7 minute (be preferably placed on food steamer and steam 30 minutes, be rolled into smalls with ferrum spoon, be placed on iron plate and smoke 5 minutes).
Above-mentioned preparation method, 3. Bombyx Batryticatus light salt brine is soaked 13-18 minute (preferably Bombyx Batryticatus light salt brine being soaked 15 minutes) by step.
Above-mentioned preparation method, 4. step scalds 3-5 time with boiling hot deep fat, dries in the air to crisp, grinds to form smalls, crosses 130-150 mesh sieve stand-by (preferably scald 4 times with boiling hot deep fat, dry in the air to crisp, grind to form smalls, cross 140 mesh sieves stand-by).
Above-mentioned preparation method, 5. step adds Mel (preferably adding Mel until boiling after 4 minutes) until boiling after 3-5 minute.
Above-mentioned preparation method, the consumption of step 5. water be the 1.3-1.8 of aromatic vinegar weight doubly, cover lid decocts 14-17 minute slowly, crosses 210-230 order drainage screen (consumption of preferred water is 1.5 times of aromatic vinegar weight, and cover lid decocts 16 minutes slowly, crosses 220 order drainage screens).
Said composition is to the Be very effective of dysfunctional uterine bleeding, dysfunctional uterine hemorrhage, not only there is effect that is antibacterial, hemostasis, fundamentally thoroughly can also treat dysfunctional uterine bleeding, and can for dysfunctional uterine bleeding, reason determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs that dysfunctional uterine hemorrhage is different, the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
Treat a compositions for dysfunctional uterine bleeding, the pharmacological effect of each crude drug is respectively:
Cornu Cervi Pantotrichum: Cornu Cervi Pantotrichum is rare medicinal herbs.Containing compositions such as phospholipid, glycolipid, glue fat, hormone, fatty acid, aminoacid, protein and calcium, phosphorus, magnesium, sodium in Cornu Cervi Pantotrichum, wherein aminoacid ingredient accounts for the over half of total composition.Cornu Cervi Pantotrichum is warm in nature and not dry, have and rouse oneself and improve body function, to patient after asthenia universalis, prolonged illness, diseases such as having good Tonic Action, suffer from a deficiency of the kidney, dizzy, deaf, order is dark, sexual impotence, spermatorrhea, cold womb are infertile, weakness and emaciation, Mental fatigue, fear of cold, spinal column cold type of pain, muscles and bones flaccidity are soft, bleeding not during menses, carbuncle of yin nature are not held back and prolonged illness is deficient.
Herba Ecliptae: sweet in the mouth acid, cool in nature, enter Liver and kidney two warp, nontoxic.Nourishing the liver and kidney, cooling blood for hemostasis, can control various haematemesis, the diseases such as enterorrhagia.Smash juice painting eyebrow to send out, can promote hair growth, for oral administration have black hair, hair color effect.
RHIIZOMA DIOSCOREAE fr0m Henan of China: as one of most important tonification material of Chinese medicine, RHIIZOMA DIOSCOREAE fr0m Henan of China and other conventional tonics, as Radix Ginseng, Radix Codonopsis, the Radix Astragali etc. are compared, maximum difference is also its great advantage, is without any side effects.Therefore being evaluated as " temperature compensation " " property is put down " by always doctor, is the model of " integration of edible and medicinal herbs ", and namely can to allay one's hunger use as normal diet, user does not evade, and is suitable for any crowd, any body constitution, comprises old man, child, anemia of pregnant woman and other special populations.
Fructus Mali pumilae: Fructus Mali pumilae not only can regulate gastrointestinal function, reduces cholesterol, blood pressure lowering, anti-cancer, fat-reducing, can also strengthen the memory of child.Fructus Mali pumilae is not only containing multivitamin, and lipid, mineral, saccharide etc. form the necessary nutrition of brain, and containing being conducive to the fine fibre of upgrowth and development of children, can strengthen the zinc of child's memory.Zinc forms and the closely bound up nucleic acid of memory and the requisite element of albumen, and zinc deficiency can make the dysplasia of cerebral cortex edge part hippocampus.In order to make our memory good, advise that we rationally suitably should eat of Fructus Mali pumilae more.
Galla Chinensis: be the insect gall formed after the upper parasitic times Aphidiadae insecticide horned gall aphid of the trees such as Anacardiaceae Rhus plant Fructus rhois chinensis, potanin sumac and Radix Rhois Sinicae or melaphis peitan Tsai et Tang.Composition: the insect gall master of Fructus rhois chinensis is containing Gallotannin.These tannins comprise: 1,2,3,4,6-five-O-galloyl--D-Glucose etc.Chinese gall oil fat acid: capric acid, lauric acid, myristic acid, Palmic acid, fatty acid, oleic acid, linoleic acid, linolenic acid.Again containing tannic acid, gallic acid.The property of medicine: sour, puckery, cold.Return lung, large intestine, kidney channel.Function cures mainly: astringe the lung, hidroschesis, astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs, hemostasis, removing toxic substances.Cure mainly chronic cough of deficiency lung, spontaneous sweating, chronic dysentery chronic diarrhea, proctoptosis, seminal emission, nebulousurine, various hemorrhage, carbuncle furuncle.
Radix Notoginseng: be the root of Araliaceae Radix Ginseng tree plant Radix Notoginseng.Composition: root master is containing dammarane type four-ring triterpenoid constituents: ginsenoside Rb1, Rd, Re, Rg1, Rg2, Rh1 etc., arasaponin R1, R2, R3, R4, R5, R6, R7, gypenoside etc.The property of medicine: sweet, micro-hardship, temperature.Return liver, stomach, the heart, large intestine channel.Function cures mainly: hemostasis dissipating blood stasis, subduing swelling and relieving pain.Cure mainly haematemesis, hemoptysis, hematuria, have blood in stool, dysentery, metrorrhagia, postpartum hemorrhage, traumatic hemorrhage, tumbling down damages, obstruction of qi in the chest and cardialgia, gastral cavity side of body pain for a long time, and lump in the abdomen amasss block, blood stasis amenorrhea, dysmenorrhea, stomachache of being retarded by silt puerperal, sore, carbuncle and painful swelling.
Bombyx Batryticatus: have another name called Bombyx Batryticatus, flying worm, Bombyx Batryticatus worm, the larva belonging to animal bombyx mori for Bombycidae silkworm infects muscardine and ossified Scorpio.The property of medicine: this product is slightly cylindrical, how bending shrinkage, surperficial lark, matter is hard and crisp, frangibility, acrid in the mouth, salty, and property is put down.Composition: Bombyx Batryticatus containing protein, oxamidic acid., and contains lysine, leucine, aspartic acid etc. 17 seed amino acid.According to modern pharmacological research find, this medical instrument have expelling wind and relieving convulsion, dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat, convulsion, hypoglycemic effect, for apoplexy, migraine and general headache, laryngopharynx swelling and pain, rubella etc.
Cirsii japonici,radix: another name horse Ji, brave Ji, cat Ji, field thistle, Herba seu Radix Cirsii Japonici (Radix Saussureae cordifoliae), field thistle dish etc.Flavor efficacy is sweet, bitter, the cooler profit of property.Merit arrogates to oneself removing heat from blood, hemostasis, is applicable to treat the multiple hemorrhage caused by bleeding due to blood-heat, as spitting of blood, epistaxis, metrorrhagia, hematuria etc.; Be longer than blood stasis dispelling again, subduing inflammation, granulation promoting evacuation of pus.Can be used for treatment hemorrhoidal hamorrhage acute appendicitis, pain infections toxic swelling, furuncle, scrofula tuberculosis etc.
Rhizoma Cimicifugae: pungent, sweet, is slightly cold.Gui Jing: return lung, spleen, large intestine, stomach warp.Effect: deliver rash, heat-clearing and toxic substances removing, ascending up spleen-Qi and Yang.Cure mainly: seasonal epidemic pathogens epidemic disease, headache cold and heat, laryngalgia, aphtha, macule is not saturating; Sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women is collapsed, band, and uterus drops; Carbuncle sore tumefacting virus.
Fructus Ligustri Lucidi: be the fruit of Oleaceae Ligustrum plant Fructus Ligustri Lucidi.Composition: fruit is containing triterpenes: oleanolic acid, acetyloleanolic acid, ursolic acid, acetyl ursolic acid; Phenolic glycoside class: p-hydroxyphenylethanol, Hydroxytyrosol, nuzhenide, oleuropein, Fructus Ligustri Lucidi fruit glycosides, Fructus Ligustri Lucidi acid, Fructus Ligustri Lucidi thuja acid etc.The property of medicine: sweet, bitter, cold.Return liver, warp.Function cures mainly: liver and kidney tonifying, clearind deficient heat you, improving eyesight.Cure mainly Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision.
Placenta Hominis: Placenta Hominis is containing protein, sugar, calcium, vitamin, immune factor, estrogen, gravidity assisting ketone, steroid hormone, promoting sexual gland hormone, thyroliberin etc., the growth of mammary gland, uterus, vagina, testis can be promoted, also facilitation is had to thyroid, also there is good effect to pulmonary tuberculosis, bronchial asthma, anemia etc., grind oral or coloclysis into powder and can prevent measles or mitigation symptoms.Also certain curative effect is had to portal cirrhotic ascites and schistosomicide end-age cirrhosis ascites.
Radix Paeoniae Rubra: for thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Radix Paeoniae Rubra (parched): after frying, the property of medicine relatively relaxes, promoting blood circulation and stopping pain and not damaging the spleen and stomach, can be used for the stagnant pain of the stasis of blood.Wine Radix Paeoniae Rubra: with promoting blood circulation to remove blood stasis power victory, clearing away heat and cooling blood effect is more weak.Be used for amenorrhea or dysmenorrhea, traumatic injury.Hardship, is slightly cold.Return Liver Channel.There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling.
Carapax et Plastrum Testudinis: Carapax et Plastrum Testudinis contains several amino acids, protein, fat and calcium salt etc. containing bone gelatin, hydrolysate.Carapax et Plastrum Testudinis nourishing kidney YANG hyperactivity suppressing, replenishing kidney and strengthening bone, reinforcing the heart of nourishing blood.Cure mainly hyperactivity of YANG due to deficiency of YIN, yin asthenia generating intrinsic heat, stirring-up of pathogenic wind in the interior resulting from deficiency.To suffer from a deficiency of the kidney the atrophic debility of bones, infantile metopism.Deficiency of YIN-blood, palpitation with fear, insomnia, forgetful.
Mel: 1, Mel can improve the composition of blood, promote heart and brain and vascular function, therefore often take and have protective effect for very beneficial 2. Mel of cardiovascular patient to liver, liver cell regeneration can be impelled, certain inhibitory action 3. that is formed of fatty liver is eaten Mel and can be regained one's strength of body rapidly, allaying tiredness, 4. Mel that build up one's resistance to disease also have the effect of sterilization, often edible Mel, not only without prejudice to tooth, effect 5. Mel that can also play sterilizing in oral cavity can treat the skin damage of moderate, particularly scald, during by Mel as skin wound dressing, antibacterial cannot grow people's oral 1 soupspoon Mel (adding in 1 glass of warm water) before sleep every day of 6. insomnias, can help to fall asleep as early as possible 7. Mel can also loosening bowel to relieve constipation (as long as the real Mel of mature native has the effect of loosening bowel to relieve constipation), 8, antioxidation, the antioxidant containing incredible amount in Mel, the rubbish------oxygen-derived free radicals in his energy purged body, reaches anticancer, anti-aging effect.
Aromatic vinegar: 1, vinegar can whet the appetite, promotes the secretion of saliva and gastric juice, helps digest absorption, make honey stomach, promoting digestion and removing stagnation; 2, vinegar has well antibacterial and bactericidal action, can effectively prevention of intestinal tract disease, influenza and respiratory disorder; 3, vinegar can improve appetite, reduce cholesterol, is the potion good recipe of the cardiovascular patients such as hypertension; 4, vinegar can play a very good protection to skin, hair, the record that ancient Chinese medical science is used as medicine with regard to useful vinegar, thinks that it has effect of hair growth promoting, beauty treatment, blood pressure lowering, fat-reducing; 5, vinegar can allaying tiredness, hypnotic, and can alleviate carsickness, seasick malaise symptoms; 6, vinegar can also reduce the alcohol concentration in gastrointestinal tract and blood, plays the effect of relieving alcoholic intoxication; 7, vinegar makes Os Gallus domesticus in addition, Fin Mustetus manazo softens, and promotes the effect that calcium absorption enters.Dietetic therapy effect: the smell of vinegar is bitter, warm in nature, enters liver, stomach warp; There is dissipating blood stasis, hemostasis, removing toxic substances, effect of parasite killing; Cure mainly puerperal blood faints, jaundice, yellowish perspiration, haematemesis, epistaxis, stool hematochezia, pudendum dizziness, feeling of fullness in the head, uncomfortable in chest, carbuncle skin ulcer swollen, can separate again flesh of fish dish poison.
The present invention is by Cornu Cervi Pantotrichum, Herba Ecliptae, RHIIZOMA DIOSCOREAE fr0m Henan of China, Fructus Mali pumilae, Galla Chinensis, Radix Notoginseng, Bombyx Batryticatus, cirsii japonici,radix, Rhizoma Cimicifugae, Fructus Ligustri Lucidi, Placenta Hominis, Radix Paeoniae Rubra, Carapax et Plastrum Testudinis, Mel and aromatic vinegar are combined, can enrich blood, hemostasis, benefiting qi and raising yang, nourishing blood for regulating menstruation, righting method is evil, all medicines coordinate, to dysfunctional uterine bleeding, there is better therapeutic effect, the present composition is based on the principle of traditional Chinese medical herbal treatment dysfunctional uterine bleeding, cheap, life-time service also can not cause the financial burden of patient, treat the ideal medicine of dysfunctional uterine bleeding.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1: a kind of compositions for the treatment of dysfunctional uterine bleeding, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): 4.5 parts, Cornu Cervi Pantotrichum, Herba Ecliptae 4.5 parts, RHIIZOMA DIOSCOREAE fr0m Henan of China 3 parts, Fructus Mali pumilae 3 parts, Galla Chinensis 3 parts, Radix Notoginseng 4.5 parts, Bombyx Batryticatus 0.9 part, cirsii japonici,radix 9 parts, Rhizoma Cimicifugae 9 parts, Fructus Ligustri Lucidi 6 parts, Placenta Hominis 6 parts, Radix Paeoniae Rubra 4 parts, Carapax et Plastrum Testudinis 3 parts, Mel 40 parts, aromatic vinegar 200 parts.
The preparation method of the compositions of above-mentioned treatment dysfunctional uterine bleeding, step is as follows:
1. Carapax et Plastrum Testudinis is cleaned up to be fired to and be popular in, drop in decoction of black soybean and cool, take out and grind to form smalls to cross 80 mesh sieves stand-by;
2. RHIIZOMA DIOSCOREAE fr0m Henan of China and Fructus Mali pumilae are cleaned up, chopping, is placed in the interior white sugar of clean plate and mixes thoroughly, be placed on food steamer and steam 20 minutes, be rolled into smalls with ferrum spoon, be placed on iron plate and smoke 3 minutes, dry in the air cool stand-by;
3. Bombyx Batryticatus light salt brine is soaked 10 minutes, it is crisp to take out parch, and it is stand-by to grind to form smalls;
4. Cornu Cervi Pantotrichum, Herba Ecliptae, Galla Chinensis, Radix Notoginseng, cirsii japonici,radix, Rhizoma Cimicifugae, Fructus Ligustri Lucidi, Placenta Hominis and Radix Paeoniae Rubra are together cleaned up, chopping, scald 2 times with boiling hot deep fat, dry in the air to crisp, grind to form smalls, cross 120 mesh sieves stand-by;
5. aromatic vinegar is placed in container, slow fire boiling is to boiling, Mel is added after 2 minutes until boiling, be stirred to rapidly and melt completely, add 1.-4. gains, after stirring, add clear water dilution, the consumption of water is 1 times of aromatic vinegar weight, cover lid decocts 13 minutes slowly, and cross 200 order drainage screens, filtrate is bottled and obtained compositions.
Model case one: golden XX, female, 38 years old, people from Jinan City, Shandong Province, main suit's menstrual onset dripping urine endlessly is had a surplus March, invalid through many hospitalizes, sees medical history, and patient menstrual's dripping urine endlessly of rising is had a surplus March, menses at present time only, dripping urine endlessly, color purple is black, accompany fritter, lower abdominal distention pain hold concurrently breast and rib the side of body distending pain do not relax, purplish tongue secretly has petechia, stringy pulse, examines as uterus is retarded by silt, stagnation of QI and blood, passages through which vital energy circulates is not smooth, and rule removing stasis to stop bleeding, helps with regulating menstruation.
Give the oral embodiment of the present invention 1 and obtain compositions, after 5 days, malaise symptoms improves, and continues to take 10 days, and self-induction is fully recovered, and follows up a case by regular visits to and has no recurrence in 1 year, also do not relax without other.
Embodiment 2: a kind of compositions for the treatment of dysfunctional uterine bleeding, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): 5 parts, Cornu Cervi Pantotrichum, Herba Ecliptae 5 parts, RHIIZOMA DIOSCOREAE fr0m Henan of China 3.5 parts, Fructus Mali pumilae 3.5 parts, Galla Chinensis 3.5 parts, Radix Notoginseng 5 parts, Bombyx Batryticatus 1.0 parts, cirsii japonici,radix 12 parts, Rhizoma Cimicifugae 9.5 parts, Fructus Ligustri Lucidi 7 parts, Placenta Hominis 7 parts, Radix Paeoniae Rubra 5 parts, Carapax et Plastrum Testudinis 4 parts, Mel 50 parts, aromatic vinegar 400 parts.
The preparation method of the compositions of above-mentioned treatment dysfunctional uterine bleeding, step is as follows:
1. Carapax et Plastrum Testudinis is cleaned up to be fired to and be popular in, drop in decoction of black soybean and cool, take out and grind to form smalls to cross 120 mesh sieves stand-by;
2. RHIIZOMA DIOSCOREAE fr0m Henan of China and Fructus Mali pumilae are cleaned up, chopping, is placed in the interior white sugar of clean plate and mixes thoroughly, be placed on food steamer and steam 40 minutes, be rolled into smalls with ferrum spoon, be placed on iron plate and smoke 8 minutes, dry in the air cool stand-by;
3. Bombyx Batryticatus light salt brine is soaked 20 minutes, it is crisp to take out parch, and it is stand-by to grind to form smalls;
4. Cornu Cervi Pantotrichum, Herba Ecliptae, Galla Chinensis, Radix Notoginseng, cirsii japonici,radix, Rhizoma Cimicifugae, Fructus Ligustri Lucidi, Placenta Hominis and Radix Paeoniae Rubra are together cleaned up, chopping, scald 6 times with boiling hot deep fat, dry in the air to crisp, grind to form smalls, cross 160 mesh sieves stand-by;
5. aromatic vinegar is placed in container, slow fire boiling is to boiling, Mel is added after 6 minutes until boiling, be stirred to rapidly and melt completely, add 1.-4. gains, after stirring, add clear water dilution, the consumption of water is 2 times of aromatic vinegar weight, cover lid decocts 18 minutes slowly, and cross 240 order drainage screens, filtrate is bottled and obtained compositions.
Embodiment 3: a kind of compositions for the treatment of dysfunctional uterine bleeding, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): 8 parts, Cornu Cervi Pantotrichum, Herba Ecliptae 8 parts, RHIIZOMA DIOSCOREAE fr0m Henan of China 5 parts, Fructus Mali pumilae 5 parts, Galla Chinensis 5 parts, Radix Notoginseng 8 parts, Bombyx Batryticatus 1.4 parts, cirsii japonici,radix 25 parts, Rhizoma Cimicifugae 11 parts, Fructus Ligustri Lucidi 11 parts, Placenta Hominis 11 parts, Radix Paeoniae Rubra 8 parts, Carapax et Plastrum Testudinis 10 parts, Mel 43 parts, aromatic vinegar 250 parts.
The preparation method of the compositions of above-mentioned treatment dysfunctional uterine bleeding, step is as follows:
1. Carapax et Plastrum Testudinis is cleaned up to be fired to and be popular in, drop in decoction of black soybean and cool, take out and grind to form smalls to cross 90 mesh sieves stand-by;
2. RHIIZOMA DIOSCOREAE fr0m Henan of China and Fructus Mali pumilae are cleaned up, chopping, is placed in the interior white sugar of clean plate and mixes thoroughly, be placed on food steamer and steam 25 minutes, be rolled into smalls with ferrum spoon, be placed on iron plate and smoke 4 minutes, dry in the air cool stand-by;
3. Bombyx Batryticatus light salt brine is soaked 13 minutes, it is crisp to take out parch, and it is stand-by to grind to form smalls;
4. Cornu Cervi Pantotrichum, Herba Ecliptae, Galla Chinensis, Radix Notoginseng, cirsii japonici,radix, Rhizoma Cimicifugae, Fructus Ligustri Lucidi, Placenta Hominis and Radix Paeoniae Rubra are together cleaned up, chopping, scald 3 times with boiling hot deep fat, dry in the air to crisp, grind to form smalls, cross 130 mesh sieves stand-by;
5. aromatic vinegar is placed in container, slow fire boiling is to boiling, Mel is added after 3 minutes until boiling, be stirred to rapidly and melt completely, add 1.-4. gains, after stirring, add clear water dilution, the consumption of water is 1.3 times of aromatic vinegar weight, cover lid decocts 14 minutes slowly, and cross 210 order drainage screens, filtrate is bottled and obtained compositions.
Embodiment 4: a kind of compositions for the treatment of dysfunctional uterine bleeding, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): 9 parts, Cornu Cervi Pantotrichum, Herba Ecliptae 9 parts, RHIIZOMA DIOSCOREAE fr0m Henan of China 6 parts, Fructus Mali pumilae 6 parts, Galla Chinensis 6 parts, Radix Notoginseng 9 parts, Bombyx Batryticatus 1.5 parts, cirsii japonici,radix 30 parts, Rhizoma Cimicifugae 12 parts, Fructus Ligustri Lucidi 12 parts, Placenta Hominis 12 parts, Radix Paeoniae Rubra 9 parts, Carapax et Plastrum Testudinis 12 parts, Mel 48 parts, aromatic vinegar 350 parts.
The preparation method of the compositions of above-mentioned treatment dysfunctional uterine bleeding, step is as follows:
1. Carapax et Plastrum Testudinis is cleaned up to be fired to and be popular in, drop in decoction of black soybean and cool, take out and grind to form smalls to cross 110 mesh sieves stand-by;
2. RHIIZOMA DIOSCOREAE fr0m Henan of China and Fructus Mali pumilae are cleaned up, chopping, is placed in the interior white sugar of clean plate and mixes thoroughly, be placed on food steamer and steam 35 minutes, be rolled into smalls with ferrum spoon, be placed on iron plate and smoke 7 minutes, dry in the air cool stand-by;
3. Bombyx Batryticatus light salt brine is soaked 18 minutes, it is crisp to take out parch, and it is stand-by to grind to form smalls;
4. Cornu Cervi Pantotrichum, Herba Ecliptae, Galla Chinensis, Radix Notoginseng, cirsii japonici,radix, Rhizoma Cimicifugae, Fructus Ligustri Lucidi, Placenta Hominis and Radix Paeoniae Rubra are together cleaned up, chopping, scald 5 times with boiling hot deep fat, dry in the air to crisp, grind to form smalls, cross 150 mesh sieves stand-by;
5. aromatic vinegar is placed in container, slow fire boiling is to boiling, Mel is added after 5 minutes until boiling, be stirred to rapidly and melt completely, add 1.-4. gains, after stirring, add clear water dilution, the consumption of water is 1.8 times of aromatic vinegar weight, cover lid decocts 17 minutes slowly, and cross 230 order drainage screens, filtrate is bottled and obtained compositions.
Model case two: Liu XX, female, 40 years old, Jiyang County, Jinan City, Shandong Province, irregular menstrual period is perpetual, hemorrhagely after passing through drippingly not to the utmost to have reached more than February, and amount polychrome is scarlet, matter thickness, with dizziness and tinnitus, soreness of the waist and knees, vexed insomnia; Look into coating nature, red, few tongue, thready and rapid pulse, examines as kidney yin is lost, disturbance of deficiency-heat inside the body, and punching is appointed caused by mistake admittedly.
Take the embodiment of the present invention 4 resulting composition after 5 days, hemorrhagely after conscious medicine slightly to alleviate, do not occur heartburn, acid regurgitation; Continue and take 5 days, malaise symptoms disappears, and appetite increases, energetic.
Embodiment 5: a kind of compositions for the treatment of dysfunctional uterine bleeding, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): 7 parts, Cornu Cervi Pantotrichum, Herba Ecliptae 7 parts, RHIIZOMA DIOSCOREAE fr0m Henan of China 4 parts, Fructus Mali pumilae 4 parts, Galla Chinensis 4 parts, Radix Notoginseng 6 parts, Bombyx Batryticatus 1.2 parts, cirsii japonici,radix 20 parts, Rhizoma Cimicifugae 10 parts, Fructus Ligustri Lucidi 9 parts, Placenta Hominis 8 parts, Radix Paeoniae Rubra 6 parts, Carapax et Plastrum Testudinis 6 parts, Mel 45 parts, aromatic vinegar 300 parts.
The preparation method of the compositions of above-mentioned treatment dysfunctional uterine bleeding, step is as follows:
1. Carapax et Plastrum Testudinis is cleaned up to be fired to and be popular in, drop in decoction of black soybean and cool, take out and grind to form smalls to cross 100 mesh sieves stand-by;
2. RHIIZOMA DIOSCOREAE fr0m Henan of China and Fructus Mali pumilae are cleaned up, chopping, is placed in the interior white sugar of clean plate and mixes thoroughly, be placed on food steamer and steam 30 minutes, be rolled into smalls with ferrum spoon, be placed on iron plate and smoke 5 minutes, dry in the air cool stand-by;
3. Bombyx Batryticatus light salt brine is soaked 15 minutes, it is crisp to take out parch, and it is stand-by to grind to form smalls;
4. Cornu Cervi Pantotrichum, Herba Ecliptae, Galla Chinensis, Radix Notoginseng, cirsii japonici,radix, Rhizoma Cimicifugae, Fructus Ligustri Lucidi, Placenta Hominis and Radix Paeoniae Rubra are together cleaned up, chopping, scald 4 times with boiling hot deep fat, dry in the air to crisp, grind to form smalls, cross 140 mesh sieves stand-by;
5. aromatic vinegar is placed in container, slow fire boiling is to boiling, Mel is added after 4 minutes until boiling, be stirred to rapidly and melt completely, add 1.-4. gains, after stirring, add clear water dilution, the consumption of water is 1.5 times of aromatic vinegar weight, cover lid decocts 16 minutes slowly, and cross 220 order drainage screens, filtrate is bottled and obtained compositions.
Experimental example 1: physical data: the clinical practice of compositions of embodiment 5 gained treatment dysfunctional uterine bleeding: screen 300 routine patients with dysfunctional uterine bleedings in 4 hospitals, wherein, 20 years old ~ 50 years old age, 15 days ~ half a year of the state of an illness.Be divided into two groups at random, experimental group and matched group, the data there was no significant differences such as two groups of ages, have comparability.
2, using method: matched group takes certain marketed drugs, the compositions that the oral the present invention of experimental group obtains according to specific embodiment 5, clear water of first having a drink after getting up early morning every day, and then drink the compositions of 50ml, and within 7 days, be a course for the treatment of, available warm water delivery service.
Criterion of therapeutical effect: recovery from illness: the clinical symptoms of dysfunctional uterine bleeding all disappears, effectively: clinical symptom relief, the state of an illness is controlled, invalid: the clinical symptoms of dysfunctional uterine bleeding is without being clearly better or increasing the weight of.With recovery from illness and the calculating effective percentage that takes a turn for the better.Treatment statistical result is in table 1.
Table 1:
Prove through clinical trial, the present composition is on treatment dysfunctional uterine bleeding, effective percentage is 98%, and cure rate is 95%, uses the present composition, can effectively alleviate by dysfunctional uterine bleeding, dysfunctional uterine hemorrhage, etc. disease, alleviate safely the misery of patient fast, and relapse rate is low, not occurring a routine side effect case in clinical, is a kind of compositions of safer effective treatment dysfunctional uterine bleeding.
Claims (10)
1. treat a compositions for dysfunctional uterine bleeding, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Cornu Cervi Pantotrichum 4.5-9 part, Herba Ecliptae 4.5-9 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 3-6 part, Fructus Mali pumilae 3-6 part, Galla Chinensis 3-6 part, Radix Notoginseng 4.5-9 part, Bombyx Batryticatus 0.9-1.5 part, cirsii japonici,radix 9-30 part is (preferred, cirsii japonici,radix 9.5-29.5 part), Rhizoma Cimicifugae 9-12 part, Fructus Ligustri Lucidi 6-12 part, Placenta Hominis 6-12 part, Radix Paeoniae Rubra 4-9 part, Carapax et Plastrum Testudinis 3-12 part, Mel 40-50 part, aromatic vinegar 200-400 part.
2. the compositions for the treatment of dysfunctional uterine bleeding according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Cornu Cervi Pantotrichum 5-8 part, Herba Ecliptae 5-8 part, RHIIZOMA DIOSCOREAE fr0m Henan of China 3.5-5 part, Fructus Mali pumilae 3.5-5 part, Galla Chinensis 3.5-5 part, Radix Notoginseng 5-8 part, Bombyx Batryticatus 1.0-1.4 part, cirsii japonici,radix 12-25 part, Rhizoma Cimicifugae 9.5-11 part, Fructus Ligustri Lucidi 7-11 part, Placenta Hominis 7-11 part, Radix Paeoniae Rubra 5-8 part, Carapax et Plastrum Testudinis 4-10 part, Mel 43-48 part, aromatic vinegar 250-350 part.
3. the compositions for the treatment of dysfunctional uterine bleeding according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: 7 parts, Cornu Cervi Pantotrichum, Herba Ecliptae 7 parts, RHIIZOMA DIOSCOREAE fr0m Henan of China 4 parts, Fructus Mali pumilae 4 parts, Galla Chinensis 4 parts, Radix Notoginseng 6 parts, Bombyx Batryticatus 1.2 parts, cirsii japonici,radix 20 parts, Rhizoma Cimicifugae 10 parts, Fructus Ligustri Lucidi 9 parts, Placenta Hominis 8 parts, Radix Paeoniae Rubra 6 parts, Carapax et Plastrum Testudinis 6 parts, Mel 45 parts, aromatic vinegar 300 parts.
4. the preparation method of composition of the treatment dysfunctional uterine bleeding according to any one of claim 1-3, is characterized in that: step is as follows:
1. Carapax et Plastrum Testudinis is cleaned up to be fired to and be popular in, drop in decoction of black soybean and cool, take out and grind to form smalls to cross 80-120 mesh sieve stand-by;
2. RHIIZOMA DIOSCOREAE fr0m Henan of China and Fructus Mali pumilae are cleaned up, chopping, is placed in the interior white sugar of clean plate and mixes thoroughly, be placed on food steamer and steam 20-40 minute, be rolled into smalls with ferrum spoon, be placed on iron plate and smoke 3-8 minute, dry in the air cool stand-by;
3. Bombyx Batryticatus light salt brine is soaked 10-20 minute, it is crisp to take out parch, and it is stand-by to grind to form smalls;
4. Cornu Cervi Pantotrichum, Herba Ecliptae, Galla Chinensis, Radix Notoginseng, cirsii japonici,radix, Rhizoma Cimicifugae, Fructus Ligustri Lucidi, Placenta Hominis and Radix Paeoniae Rubra are together cleaned up, chopping, scalds 2-6 time with boiling hot deep fat, dries in the air to crisp, grind to form smalls, crosses 120-160 mesh sieve stand-by;
5. aromatic vinegar is placed in container, slow fire boiling is to boiling, Mel is added after 2-6 minute until boiling, be stirred to rapidly and melt completely, add 1.-4. gains, after stirring, add clear water dilution, the consumption of water is 1-2 times of aromatic vinegar weight, cover lid decocts 13-18 minute slowly, and cross 200-240 order drainage screen, filtrate is bottled and obtained compositions.
5. preparation method according to claim 4, is characterized in that: 1. step is taken out and ground to form smalls and cross 90-110 mesh sieve stand-by (preferably take out grind to form smalls cross 100 mesh sieves stand-by).
6. preparation method according to claim 4, it is characterized in that: 2. step is placed on food steamer and steams 25-35 minute, be rolled into smalls with ferrum spoon, be placed in iron plate smokes and (be preferably placed on food steamer and steam 30 minutes for 4-7 minute, be rolled into smalls with ferrum spoon, be placed on iron plate and smoke 5 minutes).
7. preparation method according to claim 4, is characterized in that: 3. Bombyx Batryticatus light salt brine is soaked 13-18 minute (preferably Bombyx Batryticatus light salt brine being soaked 15 minutes) by step.
8. preparation method according to claim 4, is characterized in that: 4. step scalds 3-5 time with boiling hot deep fat, dries in the air to crisp, grind to form smalls, 130-150 mesh sieve is stand-by excessively (preferably scalds 4 times with boiling hot deep fat, dries in the air to crisp, grind to form smalls, cross 140 mesh sieves stand-by).
9. preparation method according to claim 4, is characterized in that: 5. step adds Mel (preferably adding Mel until boiling after 4 minutes) until boiling after 3-5 minute.
10. preparation method according to claim 4, it is characterized in that: the consumption of step 5. water be the 1.3-1.8 of aromatic vinegar weight doubly, cover lid decocts 14-17 minute slowly, (consumption of preferred water is 1.5 times of aromatic vinegar weight to cross 210-230 order drainage screen, cover lid decocts 16 minutes slowly, crosses 220 order drainage screens).
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| CN101703614A (en) * | 2009-11-11 | 2010-05-12 | 宋爱民 | Chinese medicinal decoction for treating dysfunctional uterine bleeding |
| CN103638262A (en) * | 2013-12-22 | 2014-03-19 | 林凡友 | Gynecological hemostatic capsule |
| CN104587127A (en) * | 2015-01-12 | 2015-05-06 | 段希福 | Traditional Chinese medicine preparation for treating dysfunctional uterine bleeding and preparation method thereof |
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- 2016-01-30 CN CN201610063132.8A patent/CN105560735A/en active Pending
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|---|---|---|---|---|
| CN101703614A (en) * | 2009-11-11 | 2010-05-12 | 宋爱民 | Chinese medicinal decoction for treating dysfunctional uterine bleeding |
| CN103638262A (en) * | 2013-12-22 | 2014-03-19 | 林凡友 | Gynecological hemostatic capsule |
| CN104587127A (en) * | 2015-01-12 | 2015-05-06 | 段希福 | Traditional Chinese medicine preparation for treating dysfunctional uterine bleeding and preparation method thereof |
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Application publication date: 20160511 |