CN105560633B - Double-elimination three-way aphtha stopping powder - Google Patents
Double-elimination three-way aphtha stopping powder Download PDFInfo
- Publication number
- CN105560633B CN105560633B CN201410533833.4A CN201410533833A CN105560633B CN 105560633 B CN105560633 B CN 105560633B CN 201410533833 A CN201410533833 A CN 201410533833A CN 105560633 B CN105560633 B CN 105560633B
- Authority
- CN
- China
- Prior art keywords
- powder
- medicine
- pain
- ulcer
- aphtha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000843 powder Substances 0.000 title claims abstract description 50
- 208000002399 aphthous stomatitis Diseases 0.000 title claims abstract description 29
- 238000003379 elimination reaction Methods 0.000 title description 3
- 239000003814 drug Substances 0.000 claims abstract description 37
- 208000007117 Oral Ulcer Diseases 0.000 claims abstract description 19
- 229940079593 drug Drugs 0.000 claims abstract description 12
- 230000000306 recurrent effect Effects 0.000 claims abstract description 12
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 6
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 6
- 244000061458 Solanum melongena Species 0.000 claims abstract description 6
- 235000002597 Solanum melongena Nutrition 0.000 claims abstract description 6
- 229940116229 borneol Drugs 0.000 claims abstract description 6
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 6
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 6
- 238000002360 preparation method Methods 0.000 claims abstract description 5
- 235000007516 Chrysanthemum Nutrition 0.000 claims abstract description 4
- 235000009388 Parthenocissus quinquefolia Nutrition 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 244000189548 Chrysanthemum x morifolium Species 0.000 claims abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 238000001704 evaporation Methods 0.000 claims description 5
- 241000233838 Commelina Species 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 claims description 3
- 241000563984 Ampelopsis Species 0.000 claims description 3
- 241000123835 Ampelopsis japonica Species 0.000 claims description 3
- 235000003097 Artemisia absinthium Nutrition 0.000 claims description 3
- 240000001851 Artemisia dracunculus Species 0.000 claims description 3
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 claims description 3
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims description 3
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 claims description 3
- 244000035851 Chrysanthemum leucanthemum Species 0.000 claims description 3
- 239000001138 artemisia absinthium Substances 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 3
- 238000000227 grinding Methods 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 3
- 241000037740 Coptis chinensis Species 0.000 claims description 2
- 240000004980 Rheum officinale Species 0.000 claims description 2
- 235000008081 Rheum officinale Nutrition 0.000 claims description 2
- 239000002671 adjuvant Substances 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 238000007873 sieving Methods 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 claims description 2
- 241000628997 Flos Species 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 20
- 208000002193 Pain Diseases 0.000 abstract description 19
- 230000036407 pain Effects 0.000 abstract description 19
- 208000025865 Ulcer Diseases 0.000 abstract description 17
- 231100000397 ulcer Toxicity 0.000 abstract description 15
- 230000001737 promoting effect Effects 0.000 abstract description 10
- 206010061218 Inflammation Diseases 0.000 abstract description 8
- 230000004054 inflammatory process Effects 0.000 abstract description 8
- 230000035876 healing Effects 0.000 abstract description 7
- 230000003467 diminishing effect Effects 0.000 abstract description 6
- 230000008961 swelling Effects 0.000 abstract description 5
- 206010018291 Gingival swelling Diseases 0.000 abstract description 4
- 230000000740 bleeding effect Effects 0.000 abstract description 4
- 208000004371 toothache Diseases 0.000 abstract description 4
- 208000005232 Glossitis Diseases 0.000 abstract description 2
- 201000007100 Pharyngitis Diseases 0.000 abstract description 2
- 240000003152 Rhus chinensis Species 0.000 abstract description 2
- 235000014220 Rhus chinensis Nutrition 0.000 abstract description 2
- 238000000605 extraction Methods 0.000 abstract description 2
- 238000005469 granulation Methods 0.000 abstract description 2
- 230000003179 granulation Effects 0.000 abstract description 2
- 230000023597 hemostasis Effects 0.000 abstract description 2
- 241000219099 Parthenocissus quinquefolia Species 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000956 nontoxicity Toxicity 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 230000017423 tissue regeneration Effects 0.000 description 6
- 210000000214 mouth Anatomy 0.000 description 5
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 4
- 210000004877 mucosa Anatomy 0.000 description 4
- 208000032843 Hemorrhage Diseases 0.000 description 3
- 206010052428 Wound Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 2
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Chinese gallotannin Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 description 2
- 241000723353 Chrysanthemum Species 0.000 description 2
- 244000247747 Coptis groenlandica Species 0.000 description 2
- 235000002991 Coptis groenlandica Nutrition 0.000 description 2
- 206010018286 Gingival pain Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000003628 erosive effect Effects 0.000 description 2
- 229940074391 gallic acid Drugs 0.000 description 2
- 235000004515 gallic acid Nutrition 0.000 description 2
- 206010018388 glossodynia Diseases 0.000 description 2
- 210000004379 membrane Anatomy 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 208000018962 mouth sore Diseases 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 210000002105 tongue Anatomy 0.000 description 2
- 230000036269 ulceration Effects 0.000 description 2
- 241001480043 Arthrodermataceae Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 244000241235 Citrullus lanatus Species 0.000 description 1
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 1
- 241000186227 Corynebacterium diphtheriae Species 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010013700 Drug hypersensitivity Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241001005836 Euchloe ausonia Species 0.000 description 1
- 206010018276 Gingival bleeding Diseases 0.000 description 1
- 208000024283 Gingival haemorrhages Diseases 0.000 description 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000219061 Rheum Species 0.000 description 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 241000193998 Streptococcus pneumoniae Species 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 201000003465 angular cheilitis Diseases 0.000 description 1
- 230000001760 anti-analgesic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 235000019606 astringent taste Nutrition 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000005178 buccal mucosa Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 208000007287 cheilitis Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000037304 dermatophytes Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 201000005311 drug allergy Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229920002824 gallotannin Polymers 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000002741 leukoplakia Diseases 0.000 description 1
- 201000011486 lichen planus Diseases 0.000 description 1
- 229960004194 lidocaine Drugs 0.000 description 1
- 210000000088 lip Anatomy 0.000 description 1
- 238000002690 local anesthesia Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 210000003254 palate Anatomy 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000006920 protein precipitation Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 208000003265 stomatitis Diseases 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229960002117 triamcinolone acetonide Drugs 0.000 description 1
- YNDXUCZADRHECN-JNQJZLCISA-N triamcinolone acetonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O YNDXUCZADRHECN-JNQJZLCISA-N 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
- DSNIKOZTDZBWKD-XMNJDQQWSA-N yejuhua lactone Chemical compound O([C@H]1C2C[C@H]([C@@](C3C1C(=CC3)C)(C)O)OC(=O)C)C(=O)C2(C1(C)C=C2)CC22C1[C@H]1OC(=O)C(=C)C1CC[C@@]2(C)O DSNIKOZTDZBWKD-XMNJDQQWSA-N 0.000 description 1
Images
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a pure traditional Chinese medicine preparation Liangxiaosanzhi aphtha powder for treating recurrent oral ulcer, belonging to the field of traditional Chinese medicines. The powder solves the problems of limited functions, unsatisfactory effects and long treatment course of the existing similar medicines, and integrates the functions of diminishing inflammation, reducing swelling, relieving pain, stopping ulcer and stopping bleeding into one prescription. The raw material medicaments comprise the following components in percentage: 20-50% of frosted eggplant, 20-30% of Chinese gall, 15-25% of Japanese ampelopsis root, 2-8% of borneol, 1-5% of ambergris and 8-12% of chrysanthemum concentrate powder are added, the powder has good effects of diminishing inflammation, reducing swelling, relieving pain, astringing and promoting granulation and promoting rapid healing of ulcer surfaces, and has short treatment course and quick response when used for treating recurrent oral ulcer; has good effects of treating gum swelling and pain, toothache due to wind decay, hemostasis and pain relieving by tooth extraction, glossitis, pharyngitis and the like. The powder is a pure Chinese medicinal preparation, has no toxicity, side effects or irritation, and has the advantages of simple process, convenient use, small dosage and low cost.
Description
Technical Field
The invention relates to a pure traditional Chinese medicine powder for treating recurrent oral ulcer.
Background
At present, the traditional Chinese medicine external powder for treating recurrent oral ulcer comprises houfeng powder, changansan powder, tin powder, Bingpeng powder, yin nourishing and tissue regeneration promoting powder, watermelon frost and the like, and the traditional Chinese medicine external powder can treat sore throat and also has the defect of poor effects of diminishing inflammation, relieving pain, astringing and promoting tissue regeneration when being used for treating oral ulcer. The oral ulcer membrane of western medicine has good effect, but is limited to a few ulcers, a plurality of ulcers are inconvenient, and the oral ulcer membrane is easy to fall off after eating; the 0.1% triamcinolone acetonide ointment has good anti-inflammatory and analgesic effects, but the ulcer healing time is long.
Disclosure of Invention
The invention mainly solves the problems of non-ideal effects of diminishing inflammation, reducing swelling, relieving pain and stopping ulceration and long treatment course of the existing similar medicines in treating recurrent oral ulcer, and provides multifunctional pure traditional Chinese medicine powder which can completely replace the traditional Chinese medicine powder for treating recurrent oral ulcer.
The invention relates to a medicine for treating recurrent oral ulcer, which basically comprises the following components: 20-50% of frosted eggplant, 20-30% of Chinese gall, 15-25% of radix ampelopsis, 2-8% of borneol and 1-5% of ambergris.
In the traditional Chinese medicine powder for treating dental ulcer, 8-12% of concentrated powder of yellow chrysanthemum is also contained in raw materials, which are equivalent to 15g of coptis root, 20g of rhubarb, 20g of oriental wormwood, 50g of dayflower and 25g of wild chrysanthemum flower. Aims to enhance the effects of diminishing inflammation, clearing away heat and toxic material, promoting granulation and healing wound of the main drug. The concentrated powder can inhibit or kill Staphylococcus aureus, hemolytic streptococcus, Diplococcus pneumoniae, Corynebacterium diphtheriae, Pseudomonas aeruginosa, Escherichia coli, influenza virus, dermatophyte, etc. parasitizing in oral cavity. Wherein the coptis root is used for purging fire and drying dampness and treating mouth and tongue sore toothache; the dayflower herb can clear heat and cool blood, treat all inflammations in the mouth, has good effect particularly on treating oral ulcer, and can shrink capillary vessels to stop bleeding; herba Artemisiae Scopariae detoxifies and resists bacteria, it is good for treating eczema and running water, radix Et rhizoma Rhei detoxifies and carbuncle, purges heat and relaxes the bowels, treat mouth and tongue sores, gum swelling and pain, contain tannin and can astringe ulcer wound surface, contain gallic acid and can stop bleeding; ye Ju Hua is indicated for all kinds of sores and ulcers because it can clear heat and promote regeneration of wound healing.
The medicine for treating recurrent oral ulcer has the following effects: the frost eggplant has the effects of diminishing inflammation and removing swelling and is mainly used for treating aphtha and toothache; galla chinensis contains gallotannin and can precipitate protein, and tissue protein thereof is instantly coagulated to form a layer of capsule to play a role in astringency protection after contacting ulcer mucosa, nerve ending protein precipitation causes local anesthesia to relieve pain, and wound surface is contracted by small blood vessel to stop bleeding by containing gallic acid; the ampelopsis japonica eliminates stagnation and relieves pain, contains mucus and promotes tissue regeneration and heals sore, and is specially used for treating sore and carbuncle, and unhealed after ulceration for a long time; the borneol incense has the effects of clearing heat, relieving pain, accelerating inflammation elimination and promoting healing of ulcer surfaces; ambergris has the effects of promoting qi and blood circulation, eliminating stagnation and relieving pain, and modern medicine proves that the ambergris contains oral mucosa repair factors, and can be used for quickly maintaining and repairing damaged mucosa cells, improving the immunity of a diseased part and preventing relapse in the future. The main drug has the same bacteriostatic and bactericidal effects as the additional drugs. The main and auxiliary drugs are used together, and the curative effect is enhanced. The medicine can be used for treating recurrent oral ulcer for three days, mechanical self-traumatic oral ulcer for the next day, tooth extraction and hemostasis for three minutes, and toothache due to wind decay and gingival swelling and pain can be relieved in one minute. In addition, it can be used for treating oral ulcer, glossitis, pharyngolaryngitis, and angular stomatitis due to drug allergy, scald, lichen planus, and leukoplakia.
Detailed Description
Formula and preparation of a powder for treating aphtha. Main drugs: 20-50g of frosted eggplant, charring for storage, and grinding 20-30g of gallnut, 15-25g of ampelopsis japonica, 2-8g of borneol and 1-5g of ambergris into fine powder; adding concentrated powder of yellow chrysanthemum: decocting 15g of coptis chinensis, 20g of rheum officinale and 500ml of water for 20 minutes, then adding 20g of oriental wormwood, 50g of dayflower and 25g of wild chrysanthemum flower for decocting for 30 minutes, filtering out decoction while hot, adding 400ml of water into medicine residues for decocting for 30 minutes, filtering out decoction, combining two decoctions, dividing into 50-80ml equal parts, placing the mixture in a 100ml evaporating dish, placing the mixture on a boiling water bath for evaporating, and collecting 8-12g of concentrated powder; mixing the main and adjuvant medicines, pulverizing with high speed (25000 r/min) pulverizer, sieving with 120 mesh sieve, sterilizing, and bottling 3g per bottle.
The clinical application is as follows: the powder is directly sprayed on affected parts, and can be used for treating various oral ulcer 3-5 times daily, three days as a treatment course, and other gingival swelling and pain, laryngopharynx swelling and pain, stomatitis, gingival hemorrhage, etc. 3-4 times daily, with the degree of healing. The powder can be used for external treatment, and directly acts on focus, and the superfine powder has adhesion effect of radix Ampelopsis and ambergris, and mucosa penetration effect of Borneolum and Frost fructus Solani Melongenae, and is more beneficial to absorption and exertion of medicine.
The Shuangxiaosan powder for treating aphtha is compared with the Yin-nourishing and tissue regeneration-promoting powder. The observation group uses the powder for treating the disease of two or three kinds of diseases in 68 cases, and the comparison group uses the powder for nourishing yin and promoting tissue regeneration in 66 cases, and the two courses of treatment are respectively carried out. Because the recurrent oral ulcer has the self-limiting characteristic of being healed in 7-10 days, the curative effect is judged as follows: the cure in one course of treatment is obvious effect, the cure in two courses of treatment is effective, and the cure in more than 7 days is ineffective. The two groups of total effective rates and the daily healing conditions are shown in the attached table and the attached drawing, and the attached drawing is the comparison of the daily healing conditions of the powder and the yin nourishing and tissue regeneration promoting powder.
Comparing the powder for treating aphtha with the powder for nourishing yin and promoting tissue regeneration
Number of observers | Show effect | Is effective | Is not effective | The total effective rate% | |
Observation group | 68 | 56 | 12 | 0 | 100 |
Control group | 66 | 35 | 20 | 11 | 83.3 |
The total effective rate of the observation group is 100%, the first course of treatment of the patient is cured by 82.3%, the treatment period is shortened by half compared with that of the control group, and no ineffective case exists, which shows that the powder has better effect than the yin-nourishing and granulation-promoting powder.
Typical cases are:
1. a certain land, male, 53 years old, complain about more than ten years of recurrent oral ulcer, relapse six times per year averagely, the ulcer number is 8-12, the duration is 7-14 days, lip, buccal mucosa, palate and tongue are well developed, the powder has the typical characteristics of red, yellow, concave and pain, 2% lidocaine diluent is needed to be used for gargle and pain relief after each meal, the pain is not enough, the powder is applied for two courses of treatment, the relapse period is prolonged to half a year, two courses of treatment are reused, and no relapse occurs in one year after follow-up.
2. When a certain plum is in 32 years old and suffers from herpes-like aphtha, dozens of sesame-sized ulcers appear during the attack, the ulcers are distributed in a 'starry sky' shape, the burning pain is obvious, the pain of eating and speaking is aggravated, the life quality is seriously influenced, the ulcer surface is repaired after two treatment courses of treatment by using the powder, and the ulcers do not relapse after two follow-up years.
3. Certain Tang Dynasty, female, 28 years old, oral cavity both cheek mucosa, bilateral gum symmetrically appeared pearl white speckle-like damage and accompanied with erosion, the burning pain was obvious, diagnosis was flat tongue , two courses of treatment with the powder, the pain disappeared, the white speckle subsided, the erosion face was repaired.
Claims (2)
1. A pure traditional Chinese medicine preparation Liangxiaosanzhi aphtha powder for treating recurrent oral ulcer is characterized in that: the composition consists of two dosage form powder medicines of a main medicine and an additional medicine, wherein the main medicine consists of the following raw material medicines in percentage by weight: 20-50% of solanum melongena, 20-30% of gallnut, 15-25% of radix ampelopsis, 2-8% of borneol and 1-5% of ambergris; the adjuvant drug is a concentrated powder of flos Chrysanthemi with a content of 8-12% and is prepared from crude drugs including Coptidis rhizoma 15g, radix et rhizoma Rhei 20g, herba Artemisiae Scopariae 20g, herba Commelinae 50g, and flos Chrysanthemi Indici 25 g.
2. The preparation method of the powder for eliminating aphtha according to claim 1, which is characterized in that: the main medicine part is directly prepared into powder: 20-50g of frosted eggplant, charring for storage, and grinding 20-30g of gallnut, 15-25g of ampelopsis japonica, 2-8g of borneol and 1-5g of ambergris into fine powder; decocting the part of the additional medicine, and then evaporating the decocted medicine in boiling water bath to obtain concentrated chrysanthemum powder: decocting 15g of coptis chinensis, 20g of rheum officinale and 500ml of water for 20 minutes, then adding 20g of oriental wormwood, 50g of dayflower and 25g of wild chrysanthemum flower for decocting for 30 minutes, filtering out the decoction while the decoction is hot, adding 400ml of water into the residue for decocting for 30 minutes, filtering out the decoction, combining the two decoctions, dividing into 50-80ml equal parts, putting the equal parts into a 100ml evaporating dish, putting the equal parts on a boiling water bath for evaporating to dryness, and collecting 8-12g of concentrated powder; mixing the main medicine and the additional medicine powder, grinding into fine powder by a high-speed 25000r/min grinder, sieving with a 120-mesh sieve, sterilizing, and then respectively placing into bottles, wherein each bottle contains 3g of the medicine for later use.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410533833.4A CN105560633B (en) | 2014-10-12 | 2014-10-12 | Double-elimination three-way aphtha stopping powder |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410533833.4A CN105560633B (en) | 2014-10-12 | 2014-10-12 | Double-elimination three-way aphtha stopping powder |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105560633A CN105560633A (en) | 2016-05-11 |
CN105560633B true CN105560633B (en) | 2020-03-17 |
Family
ID=55871645
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410533833.4A Expired - Fee Related CN105560633B (en) | 2014-10-12 | 2014-10-12 | Double-elimination three-way aphtha stopping powder |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105560633B (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101703525A (en) * | 2009-11-13 | 2010-05-12 | 陈冰昆 | Externally applied medicament for treating oral diseases and preparation method thereof |
CN103372062A (en) * | 2013-08-06 | 2013-10-30 | 天津太平洋制药有限公司 | Medicament for treating thrush |
CN103385961A (en) * | 2013-08-06 | 2013-11-13 | 天津太平洋制药有限公司 | Drug for treating aphthae |
CN103800465A (en) * | 2014-03-09 | 2014-05-21 | 朱克兰 | Traditional Chinese medicine composition for treating thrush and preparation method thereof |
-
2014
- 2014-10-12 CN CN201410533833.4A patent/CN105560633B/en not_active Expired - Fee Related
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101703525A (en) * | 2009-11-13 | 2010-05-12 | 陈冰昆 | Externally applied medicament for treating oral diseases and preparation method thereof |
CN103372062A (en) * | 2013-08-06 | 2013-10-30 | 天津太平洋制药有限公司 | Medicament for treating thrush |
CN103385961A (en) * | 2013-08-06 | 2013-11-13 | 天津太平洋制药有限公司 | Drug for treating aphthae |
CN103800465A (en) * | 2014-03-09 | 2014-05-21 | 朱克兰 | Traditional Chinese medicine composition for treating thrush and preparation method thereof |
Non-Patent Citations (1)
Title |
---|
口疮小验方;李玉龙;《赤脚医生杂志》;19781227(第12期);第8页 * |
Also Published As
Publication number | Publication date |
---|---|
CN105560633A (en) | 2016-05-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102091309B (en) | Pharmaceutical composition for treating bedsore and preparation method thereof | |
CN110693997A (en) | Preparation for removing putrefaction and promoting granulation of scald and burn and preparation method thereof | |
CN102813751A (en) | Wound treatment agent | |
CN104274579A (en) | Traditional Chinese medicine oil for preventing and controlling mosquito bite and preparation method of traditional Chinese medicine oil | |
CN107913234B (en) | Pilose antler grass toothpaste and preparation method thereof | |
CN105560633B (en) | Double-elimination three-way aphtha stopping powder | |
CN116115689A (en) | Seven-orifice rhinitis-relieving spray and preparation method thereof | |
CN104491825B (en) | A kind of Chinese medicine ointment for the treatment of oral ulcer | |
CN103446564B (en) | Chinese medicine composition of a kind of anti-inflammation and preparation method thereof | |
CN102885930B (en) | Externally applied cream for treating toothache caused by heat | |
CN102885969B (en) | Externally applied cream for treating toothache caused by deficiency fire | |
CN101757490A (en) | Measles-treating pill | |
CN101336990B (en) | Medicine for treating cholecystitis | |
CN104815155A (en) | Traditional Chinese medicine drops capable of expelling wind, relieving itching and improving eyesight | |
CN102824456A (en) | Specific medicine for treating animal aftosa | |
CN103977115A (en) | External traditional Chinese medicine preparation for treating trauma and infection, and preparation method thereof | |
CN1265826C (en) | Liquid medicine for treating odontopathy | |
CN103055051B (en) | Liquid for treating burn and scald | |
CN103055134A (en) | Traditional Chinese medicine liquid for treating beriberi and processing method of traditional Chinese medicine liquid | |
CN105288269A (en) | Guashan decoction | |
CN101337062A (en) | Traditional Chinese medicine composition for treating tonsillitis | |
CN104906379A (en) | Traditional Chinese medicine ointment for treating bullous impetigo and preparation method of ointment | |
CN104758459A (en) | Traditional Chinese medicine for treating gingivitis | |
CN105560837A (en) | Drug for treating skin injuries and preparation method thereof | |
CN105456718A (en) | Medicinal extract for curing radiodermatitis and preparation thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Yang Feiyuan Inventor after: Other inventor requests not to publish the name Inventor before: Yang Feiyuan |
|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200317 |