CN105560633B - Double-elimination three-way aphtha stopping powder - Google Patents

Double-elimination three-way aphtha stopping powder Download PDF

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CN105560633B
CN105560633B CN201410533833.4A CN201410533833A CN105560633B CN 105560633 B CN105560633 B CN 105560633B CN 201410533833 A CN201410533833 A CN 201410533833A CN 105560633 B CN105560633 B CN 105560633B
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powder
medicine
pain
ulcer
aphtha
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CN105560633A (en
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杨斐渊
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Abstract

The invention relates to a pure traditional Chinese medicine preparation Liangxiaosanzhi aphtha powder for treating recurrent oral ulcer, belonging to the field of traditional Chinese medicines. The powder solves the problems of limited functions, unsatisfactory effects and long treatment course of the existing similar medicines, and integrates the functions of diminishing inflammation, reducing swelling, relieving pain, stopping ulcer and stopping bleeding into one prescription. The raw material medicaments comprise the following components in percentage: 20-50% of frosted eggplant, 20-30% of Chinese gall, 15-25% of Japanese ampelopsis root, 2-8% of borneol, 1-5% of ambergris and 8-12% of chrysanthemum concentrate powder are added, the powder has good effects of diminishing inflammation, reducing swelling, relieving pain, astringing and promoting granulation and promoting rapid healing of ulcer surfaces, and has short treatment course and quick response when used for treating recurrent oral ulcer; has good effects of treating gum swelling and pain, toothache due to wind decay, hemostasis and pain relieving by tooth extraction, glossitis, pharyngitis and the like. The powder is a pure Chinese medicinal preparation, has no toxicity, side effects or irritation, and has the advantages of simple process, convenient use, small dosage and low cost.

Description

Double-elimination three-way aphtha stopping powder
Technical Field
The invention relates to a pure traditional Chinese medicine powder for treating recurrent oral ulcer.
Background
At present, the traditional Chinese medicine external powder for treating recurrent oral ulcer comprises houfeng powder, changansan powder, tin powder, Bingpeng powder, yin nourishing and tissue regeneration promoting powder, watermelon frost and the like, and the traditional Chinese medicine external powder can treat sore throat and also has the defect of poor effects of diminishing inflammation, relieving pain, astringing and promoting tissue regeneration when being used for treating oral ulcer. The oral ulcer membrane of western medicine has good effect, but is limited to a few ulcers, a plurality of ulcers are inconvenient, and the oral ulcer membrane is easy to fall off after eating; the 0.1% triamcinolone acetonide ointment has good anti-inflammatory and analgesic effects, but the ulcer healing time is long.
Disclosure of Invention
The invention mainly solves the problems of non-ideal effects of diminishing inflammation, reducing swelling, relieving pain and stopping ulceration and long treatment course of the existing similar medicines in treating recurrent oral ulcer, and provides multifunctional pure traditional Chinese medicine powder which can completely replace the traditional Chinese medicine powder for treating recurrent oral ulcer.
The invention relates to a medicine for treating recurrent oral ulcer, which basically comprises the following components: 20-50% of frosted eggplant, 20-30% of Chinese gall, 15-25% of radix ampelopsis, 2-8% of borneol and 1-5% of ambergris.
In the traditional Chinese medicine powder for treating dental ulcer, 8-12% of concentrated powder of yellow chrysanthemum is also contained in raw materials, which are equivalent to 15g of coptis root, 20g of rhubarb, 20g of oriental wormwood, 50g of dayflower and 25g of wild chrysanthemum flower. Aims to enhance the effects of diminishing inflammation, clearing away heat and toxic material, promoting granulation and healing wound of the main drug. The concentrated powder can inhibit or kill Staphylococcus aureus, hemolytic streptococcus, Diplococcus pneumoniae, Corynebacterium diphtheriae, Pseudomonas aeruginosa, Escherichia coli, influenza virus, dermatophyte, etc. parasitizing in oral cavity. Wherein the coptis root is used for purging fire and drying dampness and treating mouth and tongue sore toothache; the dayflower herb can clear heat and cool blood, treat all inflammations in the mouth, has good effect particularly on treating oral ulcer, and can shrink capillary vessels to stop bleeding; herba Artemisiae Scopariae detoxifies and resists bacteria, it is good for treating eczema and running water, radix Et rhizoma Rhei detoxifies and carbuncle, purges heat and relaxes the bowels, treat mouth and tongue sores, gum swelling and pain, contain tannin and can astringe ulcer wound surface, contain gallic acid and can stop bleeding; ye Ju Hua is indicated for all kinds of sores and ulcers because it can clear heat and promote regeneration of wound healing.
The medicine for treating recurrent oral ulcer has the following effects: the frost eggplant has the effects of diminishing inflammation and removing swelling and is mainly used for treating aphtha and toothache; galla chinensis contains gallotannin and can precipitate protein, and tissue protein thereof is instantly coagulated to form a layer of capsule to play a role in astringency protection after contacting ulcer mucosa, nerve ending protein precipitation causes local anesthesia to relieve pain, and wound surface is contracted by small blood vessel to stop bleeding by containing gallic acid; the ampelopsis japonica eliminates stagnation and relieves pain, contains mucus and promotes tissue regeneration and heals sore, and is specially used for treating sore and carbuncle, and unhealed after ulceration for a long time; the borneol incense has the effects of clearing heat, relieving pain, accelerating inflammation elimination and promoting healing of ulcer surfaces; ambergris has the effects of promoting qi and blood circulation, eliminating stagnation and relieving pain, and modern medicine proves that the ambergris contains oral mucosa repair factors, and can be used for quickly maintaining and repairing damaged mucosa cells, improving the immunity of a diseased part and preventing relapse in the future. The main drug has the same bacteriostatic and bactericidal effects as the additional drugs. The main and auxiliary drugs are used together, and the curative effect is enhanced. The medicine can be used for treating recurrent oral ulcer for three days, mechanical self-traumatic oral ulcer for the next day, tooth extraction and hemostasis for three minutes, and toothache due to wind decay and gingival swelling and pain can be relieved in one minute. In addition, it can be used for treating oral ulcer, glossitis, pharyngolaryngitis, and angular stomatitis due to drug allergy, scald, lichen planus, and leukoplakia.
Detailed Description
Formula and preparation of a powder for treating aphtha. Main drugs: 20-50g of frosted eggplant, charring for storage, and grinding 20-30g of gallnut, 15-25g of ampelopsis japonica, 2-8g of borneol and 1-5g of ambergris into fine powder; adding concentrated powder of yellow chrysanthemum: decocting 15g of coptis chinensis, 20g of rheum officinale and 500ml of water for 20 minutes, then adding 20g of oriental wormwood, 50g of dayflower and 25g of wild chrysanthemum flower for decocting for 30 minutes, filtering out decoction while hot, adding 400ml of water into medicine residues for decocting for 30 minutes, filtering out decoction, combining two decoctions, dividing into 50-80ml equal parts, placing the mixture in a 100ml evaporating dish, placing the mixture on a boiling water bath for evaporating, and collecting 8-12g of concentrated powder; mixing the main and adjuvant medicines, pulverizing with high speed (25000 r/min) pulverizer, sieving with 120 mesh sieve, sterilizing, and bottling 3g per bottle.
The clinical application is as follows: the powder is directly sprayed on affected parts, and can be used for treating various oral ulcer 3-5 times daily, three days as a treatment course, and other gingival swelling and pain, laryngopharynx swelling and pain, stomatitis, gingival hemorrhage, etc. 3-4 times daily, with the degree of healing. The powder can be used for external treatment, and directly acts on focus, and the superfine powder has adhesion effect of radix Ampelopsis and ambergris, and mucosa penetration effect of Borneolum and Frost fructus Solani Melongenae, and is more beneficial to absorption and exertion of medicine.
The Shuangxiaosan powder for treating aphtha is compared with the Yin-nourishing and tissue regeneration-promoting powder. The observation group uses the powder for treating the disease of two or three kinds of diseases in 68 cases, and the comparison group uses the powder for nourishing yin and promoting tissue regeneration in 66 cases, and the two courses of treatment are respectively carried out. Because the recurrent oral ulcer has the self-limiting characteristic of being healed in 7-10 days, the curative effect is judged as follows: the cure in one course of treatment is obvious effect, the cure in two courses of treatment is effective, and the cure in more than 7 days is ineffective. The two groups of total effective rates and the daily healing conditions are shown in the attached table and the attached drawing, and the attached drawing is the comparison of the daily healing conditions of the powder and the yin nourishing and tissue regeneration promoting powder.
Comparing the powder for treating aphtha with the powder for nourishing yin and promoting tissue regeneration
Number of observers Show effect Is effective Is not effective The total effective rate%
Observation group 68 56 12 0 100
Control group 66 35 20 11 83.3
The total effective rate of the observation group is 100%, the first course of treatment of the patient is cured by 82.3%, the treatment period is shortened by half compared with that of the control group, and no ineffective case exists, which shows that the powder has better effect than the yin-nourishing and granulation-promoting powder.
Typical cases are:
1. a certain land, male, 53 years old, complain about more than ten years of recurrent oral ulcer, relapse six times per year averagely, the ulcer number is 8-12, the duration is 7-14 days, lip, buccal mucosa, palate and tongue are well developed, the powder has the typical characteristics of red, yellow, concave and pain, 2% lidocaine diluent is needed to be used for gargle and pain relief after each meal, the pain is not enough, the powder is applied for two courses of treatment, the relapse period is prolonged to half a year, two courses of treatment are reused, and no relapse occurs in one year after follow-up.
2. When a certain plum is in 32 years old and suffers from herpes-like aphtha, dozens of sesame-sized ulcers appear during the attack, the ulcers are distributed in a 'starry sky' shape, the burning pain is obvious, the pain of eating and speaking is aggravated, the life quality is seriously influenced, the ulcer surface is repaired after two treatment courses of treatment by using the powder, and the ulcers do not relapse after two follow-up years.
3. Certain Tang Dynasty, female, 28 years old, oral cavity both cheek mucosa, bilateral gum symmetrically appeared pearl white speckle-like damage and accompanied with erosion, the burning pain was obvious, diagnosis was flat tongue , two courses of treatment with the powder, the pain disappeared, the white speckle subsided, the erosion face was repaired.

Claims (2)

1. A pure traditional Chinese medicine preparation Liangxiaosanzhi aphtha powder for treating recurrent oral ulcer is characterized in that: the composition consists of two dosage form powder medicines of a main medicine and an additional medicine, wherein the main medicine consists of the following raw material medicines in percentage by weight: 20-50% of solanum melongena, 20-30% of gallnut, 15-25% of radix ampelopsis, 2-8% of borneol and 1-5% of ambergris; the adjuvant drug is a concentrated powder of flos Chrysanthemi with a content of 8-12% and is prepared from crude drugs including Coptidis rhizoma 15g, radix et rhizoma Rhei 20g, herba Artemisiae Scopariae 20g, herba Commelinae 50g, and flos Chrysanthemi Indici 25 g.
2. The preparation method of the powder for eliminating aphtha according to claim 1, which is characterized in that: the main medicine part is directly prepared into powder: 20-50g of frosted eggplant, charring for storage, and grinding 20-30g of gallnut, 15-25g of ampelopsis japonica, 2-8g of borneol and 1-5g of ambergris into fine powder; decocting the part of the additional medicine, and then evaporating the decocted medicine in boiling water bath to obtain concentrated chrysanthemum powder: decocting 15g of coptis chinensis, 20g of rheum officinale and 500ml of water for 20 minutes, then adding 20g of oriental wormwood, 50g of dayflower and 25g of wild chrysanthemum flower for decocting for 30 minutes, filtering out the decoction while the decoction is hot, adding 400ml of water into the residue for decocting for 30 minutes, filtering out the decoction, combining the two decoctions, dividing into 50-80ml equal parts, putting the equal parts into a 100ml evaporating dish, putting the equal parts on a boiling water bath for evaporating to dryness, and collecting 8-12g of concentrated powder; mixing the main medicine and the additional medicine powder, grinding into fine powder by a high-speed 25000r/min grinder, sieving with a 120-mesh sieve, sterilizing, and then respectively placing into bottles, wherein each bottle contains 3g of the medicine for later use.
CN201410533833.4A 2014-10-12 2014-10-12 Double-elimination three-way aphtha stopping powder Expired - Fee Related CN105560633B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703525A (en) * 2009-11-13 2010-05-12 陈冰昆 Externally applied medicament for treating oral diseases and preparation method thereof
CN103372062A (en) * 2013-08-06 2013-10-30 天津太平洋制药有限公司 Medicament for treating thrush
CN103385961A (en) * 2013-08-06 2013-11-13 天津太平洋制药有限公司 Drug for treating aphthae
CN103800465A (en) * 2014-03-09 2014-05-21 朱克兰 Traditional Chinese medicine composition for treating thrush and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703525A (en) * 2009-11-13 2010-05-12 陈冰昆 Externally applied medicament for treating oral diseases and preparation method thereof
CN103372062A (en) * 2013-08-06 2013-10-30 天津太平洋制药有限公司 Medicament for treating thrush
CN103385961A (en) * 2013-08-06 2013-11-13 天津太平洋制药有限公司 Drug for treating aphthae
CN103800465A (en) * 2014-03-09 2014-05-21 朱克兰 Traditional Chinese medicine composition for treating thrush and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
口疮小验方;李玉龙;《赤脚医生杂志》;19781227(第12期);第8页 *

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