CN105559066A - Chewable tablet containing lutein ester, zeaxanthin, blueberries and Chinese wolfberry fruits and preparation method thereof - Google Patents
Chewable tablet containing lutein ester, zeaxanthin, blueberries and Chinese wolfberry fruits and preparation method thereof Download PDFInfo
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- CN105559066A CN105559066A CN201510999367.3A CN201510999367A CN105559066A CN 105559066 A CN105559066 A CN 105559066A CN 201510999367 A CN201510999367 A CN 201510999367A CN 105559066 A CN105559066 A CN 105559066A
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- zeaxanthin
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- blueberry
- powder
- lutein ester
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- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 title claims abstract description 40
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 title claims abstract description 39
- JKQXZKUSFCKOGQ-JLGXGRJMSA-N (3R,3'R)-beta,beta-carotene-3,3'-diol Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-JLGXGRJMSA-N 0.000 title claims abstract description 35
- JKQXZKUSFCKOGQ-LQFQNGICSA-N Z-zeaxanthin Natural products C([C@H](O)CC=1C)C(C)(C)C=1C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-LQFQNGICSA-N 0.000 title claims abstract description 35
- QOPRSMDTRDMBNK-RNUUUQFGSA-N Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCC(O)C1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C QOPRSMDTRDMBNK-RNUUUQFGSA-N 0.000 title claims abstract description 35
- JKQXZKUSFCKOGQ-LOFNIBRQSA-N all-trans-Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C JKQXZKUSFCKOGQ-LOFNIBRQSA-N 0.000 title claims abstract description 35
- 239000007910 chewable tablet Substances 0.000 title claims abstract description 35
- 235000010930 zeaxanthin Nutrition 0.000 title claims abstract description 35
- 239000001775 zeaxanthin Substances 0.000 title claims abstract description 35
- 229940043269 zeaxanthin Drugs 0.000 title claims abstract description 35
- 240000000851 Vaccinium corymbosum Species 0.000 title claims abstract description 34
- 235000003095 Vaccinium corymbosum Nutrition 0.000 title claims abstract description 34
- 235000017537 Vaccinium myrtillus Nutrition 0.000 title claims abstract description 34
- 235000021014 blueberries Nutrition 0.000 title claims abstract description 34
- 235000015468 Lycium chinense Nutrition 0.000 title claims abstract description 21
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 244000241872 Lycium chinense Species 0.000 title abstract description 5
- 235000013399 edible fruits Nutrition 0.000 title abstract description 3
- 229940068682 chewable tablet Drugs 0.000 title abstract 3
- 239000000843 powder Substances 0.000 claims abstract description 50
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 37
- 239000000314 lubricant Substances 0.000 claims abstract description 19
- 239000000203 mixture Substances 0.000 claims abstract description 15
- 244000007021 Prunus avium Species 0.000 claims abstract description 11
- 235000010401 Prunus avium Nutrition 0.000 claims abstract description 11
- 244000241838 Lycium barbarum Species 0.000 claims description 49
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 49
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 239000003826 tablet Substances 0.000 claims description 12
- 239000002245 particle Substances 0.000 claims description 9
- 239000011122 softwood Substances 0.000 claims description 8
- 238000001291 vacuum drying Methods 0.000 claims description 8
- 239000011812 mixed powder Substances 0.000 claims description 6
- 235000020985 whole grains Nutrition 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 5
- 239000000080 wetting agent Substances 0.000 claims description 5
- 239000012535 impurity Substances 0.000 claims description 4
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- 241000238631 Hexapoda Species 0.000 claims description 3
- 241000607479 Yersinia pestis Species 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 3
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- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical group CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims description 2
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 2
- 235000009508 confectionery Nutrition 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 2
- 238000012856 packing Methods 0.000 claims description 2
- 229940013618 stevioside Drugs 0.000 claims description 2
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims description 2
- 235000019202 steviosides Nutrition 0.000 claims description 2
- 239000000811 xylitol Substances 0.000 claims description 2
- 235000010447 xylitol Nutrition 0.000 claims description 2
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 2
- 229960002675 xylitol Drugs 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 10
- 230000004438 eyesight Effects 0.000 abstract description 9
- 208000003464 asthenopia Diseases 0.000 abstract description 8
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 240000002319 Citrus sinensis Species 0.000 abstract 1
- 235000005976 Citrus sinensis Nutrition 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 235000015203 fruit juice Nutrition 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 6
- 229960005375 lutein Drugs 0.000 description 5
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 description 5
- 229930014669 anthocyanidin Natural products 0.000 description 4
- 150000001452 anthocyanidin derivatives Chemical class 0.000 description 4
- 235000008758 anthocyanidins Nutrition 0.000 description 4
- 235000012680 lutein Nutrition 0.000 description 4
- 239000001656 lutein Substances 0.000 description 4
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 description 4
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 3
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 3
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- -1 oxygen carotenoid Chemical class 0.000 description 3
- 235000019155 vitamin A Nutrition 0.000 description 3
- 239000011719 vitamin A Substances 0.000 description 3
- 229940045997 vitamin a Drugs 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 102000004330 Rhodopsin Human genes 0.000 description 2
- 108090000820 Rhodopsin Proteins 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
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- 230000004304 visual acuity Effects 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 206010013082 Discomfort Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 235000017784 Mespilus germanica Nutrition 0.000 description 1
- 244000182216 Mimusops elengi Species 0.000 description 1
- 235000000560 Mimusops elengi Nutrition 0.000 description 1
- 206010057430 Retinal injury Diseases 0.000 description 1
- 235000007837 Vangueria infausta Nutrition 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 238000011169 microbiological contamination Methods 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
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- 239000002699 waste material Substances 0.000 description 1
- 235000008210 xanthophylls Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention discloses a chewable tablet containing lutein ester, zeaxanthin, blueberries and Chinese wolfberry fruits and a preparation method thereof. The chewable tablet comprises the following components in parts by weight: 1-2 parts of lutein ester, 0.1-0.5 part of zeaxanthin, 10-20 parts of blueberry juice powder, 25-35 parts of Chinese wolfberry fruit juice powder, 5-10 parts of sour and sweet orange powder, 5-10 parts of sweet cherry powder, 20-30 parts of flavoring agents and 0.2-0.6 part of lubricant. The chewable tablets has health-care effects in relieving visual fatigue and improving eyesight, solves problems that the existing products are single in composition and effectiveness, etc., and is good in mouthfeel, convenient to eat, good in absorption effect and more attractive to consumers.
Description
Technical field
The invention belongs to food technology field, relate to a kind of alleviating asthenopia, the chewable tablets improving eyesight and preparation method thereof, particularly relate to a kind of chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine and preparation method thereof.
Background technology
Lutein ester is decomposed into free xanthophyll after absorption of human body, has the basic function that crystal lutein supplements human body loss lutein.Lutein and zeaxanthin belong to containing oxygen carotenoid, and human body can not directly synthesize, and be extensively distributed in the tissue such as human serum, liver, wherein macula retinae Midst density is the highest, and they are the most active ingredient stoping light to expose to cause retinal damage.Increasing epidemiology and clinical testing show, in meals or serum, the lutein of high level and zeaxanthin can reduce eye disease risk.
International food nutritionist claim: the discovery of anthocyanidin is one of greatest discovery on 20th century health history.Anthocyanidin has to be safeguarded eye health, prevents visually impaired healthy element, and its function is the capilary protecting eyes, and then stimulates circulation; More there is the ability accelerating visual purple regeneration simultaneously, and the thing that the formal good vision of visual purple is indispensable; Be the most base substance that eyes produce vision, can strengthen adapting to the susceptibility to the dark low light level.Research shows, anthocyanidin contained in blueberry is maximum.
Matrimony vine is traditional rare traditional Chinese medicine, is again a kind of tonic food, is commonly called as " bright eye ", and the blurring of vision that ancient Chinese medicine doctor treatment deficiency of liver-blood, deficiency of kidney-YIN cause and yctalopia, taste the use fruit of Chinese wolfberry.Containing a large amount of carrotene in matrimony vine, after entering human body, under the effect of enzyme, vitamin A can be changed into.Vitamin A is always called as protection eyes, prevents the special efficacy vitamin of vision degeneration.
Summary of the invention
The invention provides a kind of chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine and preparation method thereof, the people of frequent use computer, like the children of Play Station games, the student that homework is busy, long-time motorist, and be absorbed in the people of trickle work, described chewable tablets can be selected to solve the problems such as eye fatigue, and the present invention effectively can obtain the discomforts such as link kopiopia.
For achieving the above object, technical scheme of the present invention is as follows:
A kind of chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine, described chewable tablets comprises following component: with parts by weight, lutein ester 1-2 part, zeaxanthin 0.1-0.5 part, blueberry juice powder 10-20 part, wolfberry juice powder 25-35 part, sour-sweet orange powder 5-10 part, sweet cherry powder 5-10 part, flavouring 20-30 part and lubricant 0.2-0.6 part.
Further: described chewable tablets comprises following component: with parts by weight, lutein ester 1.5 parts, zeaxanthin 0.25 part, 10 parts, blueberry juice powder, 25 parts, wolfberry juice powder, sour-sweet 5 parts, orange powder, 5 parts, sweet cherry powder, flavouring 30 parts and lubricant 0.5 part.
Further: the preparation method of described wolfberry juice powder is:
(1) raw material is selected: select fresh, full, pure color, without insect pest and the matrimony vine without moldy metamorphism;
(2) screen, impurity elimination: remove damaged rotten individual, residual with washing agent cleaning agriculture, then rinse with clear water, clean the dirt on its surface;
(3) pure water soaks: added in distilled water by clean matrimony vine and soak, the weight ratio of matrimony vine and water is 1:3 ~ 10;
(4) pull an oar and filter: being pulled an oar rapidly by matrimony vine is broken into pulpous state, centrifugal filtration, gets juice clearly;
(5) concentrated: to carry out low temperature concentration, concentrated 2-3 doubly, makes wherein solid concentration reach 17%-20%.
(6) vacuum drying: carry out vacuum drying to inspissated juice, obtains wolfberry juice powder.
Further: the temperature of described concentration is 40-70 DEG C.
Further: described vacuum drying temperature is 40 DEG C.
Further: described flavouring is at least one in D-sorbite, stevioside, sweet mellow wine or xylitol.
Further: described lubricant is dolomol.
Present invention also offers the preparation method of the described chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine, described preparation method comprises following concrete steps:
(1) sieve: each component of composition taking described content, in advance flavouring and lubricant are pulverized, cross 80 mesh sieves;
(2) mix: lutein ester, zeaxanthin, blueberry juice powder, wolfberry juice powder, sour-sweet orange powder, sweet cherry powder, flavouring and lubricant are put in mixer and mixes, mix, obtain mixed powder;
(3) softwood processed and particle: add ethanolic solution and make wetting agent softwood in mixed powder, stir, sieve obtained wet granular;
(4) dried particles and whole grain: described wet granular is dry, sieves, then it is even to add mix lubricant;
(5) compressing tablet: then hybrid particles is placed in tablet press machine compressing tablet and obtains tablet;
(6) carry out packing and checking.
Further: adding volume ratio in described step (3) is that the ethanolic solution of 55%-60% makes wetting agent softwood, stirs, and crosses 18 mesh sieves and granulates.
Further: by wet granular dry 12min at 65 DEG C in described step (4), cross the whole grain of 40 mesh sieve.
Advantage of the present invention and technique effect are: the present invention has prepared a kind of chewable tablets of instant, and people can carry with, and mouthfeel is good, have good market application foreground.This chewable tablets prepared not only has alleviating asthenopia, improves the health-care effect of eyesight, and have anti-oxidant, pre-anti-cancer, fatigue-resisting function concurrently, solve the problems such as composition and effect in existing product be single, and mouthfeel is good, instant, good absorbing effect, does not add any essence and spices, fully meets the requirement of people to health.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme of the present invention is further described in detail.
Embodiment 1
Chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine described in the present embodiment contains following component composition, with parts by weight: lutein ester 1.5 parts, zeaxanthin 0.25 part, 20 parts, blueberry juice powder, 25 parts, wolfberry juice powder, 5 parts, sour-sweet orange powder, 5 parts, sweet cherry powder, flavouring 25 parts and lubricant 0.6 part.Said components can adopt commercial goods, and described wolfberry juice powder also can adopt specific preparation method to obtain.
The preparation method of wolfberry juice powder of the present invention is: raw material selection-screening, impurity elimination-pure water soak-are pulled an oar and filtered-concentrate (protecting look)-vacuum drying-packaging, inspection:
1, raw material is selected: select fresh, full, pure color, matrimony vine without insect pest and moldy metamorphism;
2, screen, impurity elimination: take out damaged rotten individual, residual with washing agent cleaning agriculture, then rinse with clear water, clean the dirt on its surface;
3, pure water soaks: added by clean matrimony vine in distilled water and soak 30 minutes, the weight ratio of matrimony vine and water is 1:5;
4, pull an oar, filter: put into beater making beating and be broken into pulpous state, broken wanting rapidly, is avoided with air Long contact time, slurries being oxidized and brown stain is occurred, select type juice extractor, broken suitable, cross and slightly can affect squeezing effect, cross detailed rules and regulations and can affect crushing juice rate, centrifugal filtration, get juice clearly.
5, concentrated: to adopt low temperature thickener Chinese wolfberry clear juice to carry out low temperature concentration, thickening temperature is about 40 DEG C, reaches the object of protecting look, thus can obtain the concentrated medlar juice that color is vivid, quality better, concentration is higher, concentrated 2-3 doubly, makes wherein solid concentration reach 18%.
6, vacuum drying: utilize vacuum drier to carry out vacuum drying to inspissated juice, temperature is set to 40 DEG C, have energy consumption little, without the advantage such as the three wastes, low noise, and ensure boring consistency by Automated condtrol, without microbiological contamination chance.
The preparation method of the described chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine comprises the following steps:
(1) sieve: take each component in the composition of described consumption, in advance flavouring and lubricant are pulverized, cross 80 mesh sieves;
(2) mix: lutein ester, zeaxanthin, blueberry juice powder, wolfberry juice powder, sour-sweet orange powder, sweet cherry powder, flavouring and lubricant are put in mixer and mixes 25-35min, mix, obtain mixed powder;
(3) softwood processed and particle: add in mixed powder volume ratio be 56% ethanol water make wetting agent softwood, stir, make it " gently hold agglomerating, namely light pressure falls apart ", cross 18 mesh sieves obtain wet granular;
(4) dry particle and whole grain: by described wet granular dry 12min at 65 DEG C, crosses 40 mesh sieve whole grain, and it is even then to add mix lubricant;
(5) compressing tablet: hybrid particles is placed in tablet press machine, trimmer weight, 1g/ sheet, compressing tablet obtains tablet;
(6) pack, check, put in storage.
Embodiment 2
Chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine described in the present embodiment is composed of the following components, with parts by weight: lutein ester 1.5 parts, zeaxanthin 0.25 part, 15 parts, blueberry juice powder, 25 parts, wolfberry juice powder, sour-sweet 4 parts, orange powder, 4 parts, sweet cherry powder, flavouring 30 parts, lubricant 0.5.Concrete preparation method is with shown in embodiment 1.
Embodiment 3
Chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine described in the present embodiment is composed of the following components, with parts by weight: 30 parts, wolfberry juice powder, 10 parts, blueberry juice powder, 5 parts, sour-sweet orange powder, 5 parts, sweet cherry powder, lutein ester 1.5 parts, zeaxanthin 0.25 part, flavouring 30 parts, lubricant 0.5.Concrete preparation method is with shown in embodiment 1.
The chewable tablets prepared by adjusting above-mentioned content proportioning; not only containing the lutein ester and the zeaxanthin that eyes are had to fine protective effect; and be added with containing enrich vitamin A, anthocyanidin, carrotene, vitamin and the healthy eye such as calcium, iron must the blueberry of nutriment and matrimony vine; make its nutritive value abundanter, significantly can alleviate the symptom such as eye-blurred, kopiopia of people.
For verifying the effect of chewable tablets of the present invention, with chewable tablets of the present invention for treatment means, by 180 8-75 year crowds (wherein, 8-22 year teenager 65,23-36 year young people 55,37-58 year a middle-aged person 30,59-70 year the elderly 20, more than 70 years old old man 10) be divided into two groups and carry out human trial, test-meal group twice for each person every day, each two panels, control group then takes the placebo of equivalent, 75 days statistics curative effects.
Wherein eye fatigue disappears, clear depending on thing, and tests with standard 5 meters of logarithmic visual acuity charts, and testing standard is: eyesight promotes 1 row or the above person of 1 row, for effective; Eye fatigue, to be improved depending on thing definition, and through standard 5 meters of logarithmic visual acuity charts tests, eyesight promotes less than 1 passerby, for effectively; Eye fatigue, to look thing definition without any improvement, for invalid.The results are shown in Table shown in 1.
Table 1 eyesight testing result
Human experiment experimental result is as shown in table 1, the symptoms such as the eye fatigue of most people make moderate progress, by analysis, test-meal group improvement rate is 78.9%, and any bad reaction does not all appear in all test personnel, therefore proved patent chewable tablets all has very high edibility to each age group crowd.
Above embodiment only in order to technical scheme of the present invention to be described, but not is limited; Although with reference to previous embodiment to invention has been detailed description, for the person of ordinary skill of the art, still can modify to the technical scheme described in previous embodiment, or equivalent replacement is carried out to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.
Claims (10)
1. the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine, it is characterized in that: described chewable tablets comprises following component: with parts by weight, lutein ester 1-2 part, zeaxanthin 0.1-0.5 part, blueberry juice powder 10-20 part, wolfberry juice powder 25-35 part, sour-sweet orange powder 5-10 part, sweet cherry powder 5-10 part, flavouring 20-30 part and lubricant 0.2-0.6 part.
2. the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine according to claim 1, it is characterized in that: described chewable tablets comprises following component: with parts by weight, lutein ester 1.5 parts, zeaxanthin 0.25 part, 10 parts, blueberry juice powder, 25 parts, wolfberry juice powder, sour-sweet 5 parts, orange powder, 5 parts, sweet cherry powder, flavouring 30 parts and lubricant 0.5 part.
3. the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine according to claim 1, is characterized in that the preparation method of described wolfberry juice powder is:
(1) raw material is selected: select fresh, full, pure color, without insect pest and the matrimony vine without moldy metamorphism;
(2) screen, impurity elimination: remove damaged rotten individual, residual with washing agent cleaning agriculture, then rinse with clear water, clean the dirt on its surface;
(3) pure water soaks: added in distilled water by clean matrimony vine and soak, the weight ratio of matrimony vine and water is 1:3 ~ 10;
(4) pull an oar and filter: being pulled an oar rapidly by matrimony vine is broken into pulpous state, centrifugal filtration, gets juice clearly;
(5) concentrated: to carry out low temperature concentration, concentrated 2-3 doubly, makes wherein solid concentration reach 17%-20%;
(6) vacuum drying: carry out vacuum drying to inspissated juice, obtains wolfberry juice powder.
4. the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine according to claim 3, is characterized in that: the temperature of described concentration is 40-70 DEG C.
5. the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine according to claim 3, is characterized in that: described vacuum drying temperature is 40 DEG C.
6. the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine according to claim 1, is characterized in that: described flavouring is at least one in D-sorbite, stevioside, sweet mellow wine or xylitol.
7. the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine according to claim 1, is characterized in that: described lubricant is dolomol.
8. the preparation method of the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine described in any one of claim 1-7, is characterized in that described preparation method comprises following concrete steps:
(1) sieve: each component of composition taking described content, in advance flavouring and lubricant are pulverized, cross 80 mesh sieves;
(2) mix: lutein ester, zeaxanthin, blueberry juice powder, wolfberry juice powder, sour-sweet orange powder, sweet cherry powder, flavouring and lubricant are put in mixer and mixes, mix, obtain mixed powder;
(3) softwood processed and particle: add ethanolic solution and make wetting agent softwood in mixed powder, stir, sieve obtained wet granular;
(4) dried particles and whole grain: described wet granular is dry, sieves, then it is even to add mix lubricant;
(5) compressing tablet: then hybrid particles is placed in tablet press machine compressing tablet and obtains tablet;
(6) carry out packing and checking.
9. the preparation method of the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine according to claim 8, it is characterized in that: adding volume ratio in described step (3) is that the ethanolic solution of 55%-60% makes wetting agent softwood, stir, cross 18 mesh sieves and granulate.
10. the preparation method of the chewable tablets containing lutein ester, zeaxanthin, blueberry, matrimony vine according to claim 8, is characterized in that: by wet granular dry 12min at 65 DEG C in described step (4), crosses the whole grain of 40 mesh sieve.
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CN109123646A (en) * | 2018-09-30 | 2019-01-04 | 广东亿超生物科技有限公司 | A kind of product and method for production containing zeaxanthin, lutein ester |
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CN111000018A (en) * | 2019-11-27 | 2020-04-14 | 山东国和堂制药有限公司 | Lutein ester tablet for adults |
CN110810605A (en) * | 2019-12-02 | 2020-02-21 | 山东国和堂制药有限公司 | Sweet orange lutein ester tablet for children to eat |
CN110897158A (en) * | 2019-12-09 | 2020-03-24 | 山东国和堂制药有限公司 | Edible blueberry lutein ester tablet |
CN116076722A (en) * | 2023-02-17 | 2023-05-09 | 华北制药河北华维健康产业有限公司 | Lutein beta carotene chewable tablet and preparation method thereof |
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