CN105535892A - Traditional Chinese medicine powder for preventing and treating accumulative toxicity and preparation method of traditional Chinese medicine powder - Google Patents

Traditional Chinese medicine powder for preventing and treating accumulative toxicity and preparation method of traditional Chinese medicine powder Download PDF

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Publication number
CN105535892A
CN105535892A CN201511024817.3A CN201511024817A CN105535892A CN 105535892 A CN105535892 A CN 105535892A CN 201511024817 A CN201511024817 A CN 201511024817A CN 105535892 A CN105535892 A CN 105535892A
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parts
radix
semen
powder medicine
chinese powder
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陈世西
杜长海
史競
高飞
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BEIJING RESOURCE ASIA-PACIFIC FEED TECHNOLOGY Co Ltd
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BEIJING RESOURCE ASIA-PACIFIC FEED TECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
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    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
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    • A61K36/539Scutellaria (skullcap)
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Abstract

The invention discloses traditional Chinese medicine powder for preventing and treating accumulative toxicity. The traditional Chinese medicine powder is prepared from the following raw materials in parts by weight: 0.5-4.5 parts of radix bupleuri, 0.5-4.5 parts of scutellaria baicalensis, 0.5-4.0 parts of cassia twig, 0.3-3.0 parts of rhizoma zingiberis, 0.5-4.5 parts of trichosanthes roots, 0.3-3.0 parts of oyster, 0.1-1.0 part of rheum officinale, 0.3-3.0 part of liquorice, 0.2-1.5 parts of semen lepidii, 0.2-1.5 parts of apricot kernel, 0.2-1.5 parts of schizonepeta, 0.3-3.0 parts of fried rhizoma atractylodis macrocephalae, 0.2-1.5 parts of cortex phellodendri and 0.2-1.5 parts of periostracum cicada. The traditional Chinese medicine powder is capable of well repairingliver and kidney damages of animals caused by accumulative toxicity, improving the liver detoxification capacity and the kidneys detoxification capacity of the animals and relatively thoroughly eliminating various toxins in the animals. In addition, the invention further discloses a preparation method of the traditional Chinese medicine powder.

Description

Chinese powder medicine of control animal retention toxicosis and preparation method thereof
Technical field
The present invention relates to a kind of Chinese powder medicine, and prevent and treat Chinese powder medicine of animal retention toxicosis and preparation method thereof in particular to a kind of.
Background technology
At present, the toxin source accumulated in animal mainly contains four large classes: one, from the mycotoxin in feedstuff, as Semen Maydis, bean cake, Testa Tritici etc.; Two, from the medicated premix in feedstuff and heavy metal; Three, from the medicine that disease preventing and treating in production process uses; Four, from the toxin discharged in multiplication process of bacteria in animal body and dead rear disintegrate bacterial endotoxin out.
Prior art is mainly solved by following two modes: one is add mold toxin sorbent in feedstuff, the Montmorillonitum, zeolite, bentonite, potter's clay, Kaolin etc. of such as Aluminosilicates, the shortcoming of this method is that mold toxin sorbent can only the mycotoxin of some kind of partial adsorbates, and addition can not be excessive, otherwise likely adsorb the nutrient substance such as vitamin, aminoacid, cause Animal nutrition to lack; Two is in feedstuff, add mycotoxin catabolic enzyme, although it is higher that mycotoxin catabolic enzyme has safety, have mycotoxin and certain dispel effect, but because enzyme has specificity, mycotoxin catabolic enzyme only just has Degradation to the mycotoxin with respective action site, therefore also can only to degrade Partial Species mycotoxin, and research and development, production cost are large, end product price is high.
Summary of the invention
The object of the present invention is to provide a kind of Chinese powder medicine preventing and treating animal retention toxicosis, this Chinese powder medicine can repair the lesions of liver and kidney of animal very well, improves liver detoxification ability and the kidney toxin expelling ability of animal.
Another object of the present invention is to provide a kind of preparation method of preventing and treating the Chinese powder medicine of animal retention toxicosis, to obtain good drug efficacy and the high Chinese powder medicine of stability, this Chinese powder medicine can repair the lesions of liver and kidney of animal very well, improves liver detoxification ability and the kidney toxin expelling ability of animal.
The present invention solves its technical problem and realizes by the following technical solutions.
The present invention proposes a kind of Chinese powder medicine preventing and treating animal retention toxicosis, and Chinese powder medicine is counted by weight and comprised:
Radix Bupleuri 0.5-4.5 part, Radix Scutellariae 0.5-4.5 part, Ramulus Cinnamomi 0.5-4.0 part, Rhizoma Zingiberis 0.3-3.0 part, Radix Trichosanthis 0.5-4.5 part, Concha Ostreae 0.3-3.0 part, Radix Et Rhizoma Rhei 0.1-1.0 part, Radix Glycyrrhizae 0.3-3.0 part, Semen Lepidii (Semen Descurainiae) 0.2-1.5 part, Semen Armeniacae Amarum 0.2-1.5 part, Herba Schizonepetae 0.2-1.5 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3-3.0 part, Cortex Phellodendri 0.2-1.5 part and Periostracum Cicadae 0.2-1.5 part.
Further, in preferred embodiment of the present invention, the Chinese powder medicine of above-mentioned control animal retention toxicosis, Chinese powder medicine is counted by weight and is also comprised: Semen Plantaginis 0.2-1.5 part, Radix Saposhnikoviae 0.06-0.6 part, Bombyx Batryticatus 0.1-1.0 part and Endoconcha Sepiae 0.2-1.5 part.
Further, in preferred embodiment of the present invention, in the Chinese powder medicine of above-mentioned control animal retention toxicosis:
Radix Bupleuri is 1.5 parts, Radix Scutellariae is 1.5 parts, Ramulus Cinnamomi is 1.5 parts, Rhizoma Zingiberis is 1.0 parts, Radix Trichosanthis is 1.2 parts, Concha Ostreae is 1.0 parts, Radix Et Rhizoma Rhei is 0.3 part, Radix Glycyrrhizae is 0.8 part, Semen Lepidii (Semen Descurainiae) is 0.5 part, Semen Armeniacae Amarum is 0.5 part, Herba Schizonepetae is 0.5 part, Rhizoma Atractylodis Macrocephalae (parched) is 1.0 parts, Cortex Phellodendri be 0.5 part and Periostracum Cicadae is 0.5 part.
Further, in preferred embodiment of the present invention, the Chinese powder medicine of above-mentioned control animal retention toxicosis, also comprises: Semen Plantaginis is 0.5 part, Radix Saposhnikoviae is 0.2 part, Bombyx Batryticatus be 0.3 part and Endoconcha Sepiae is 0.5 part.
The present invention proposes a kind of preparation method of preventing and treating the Chinese powder medicine of animal retention toxicosis, and it comprises:
Material preparation step: Radix Bupleuri 0.5-4.5 part, Radix Scutellariae 0.5-4.5 part, Ramulus Cinnamomi 0.5-4.0 part, Rhizoma Zingiberis 0.3-3.0 part, Radix Trichosanthis 0.5-4.5 part, Concha Ostreae 0.3-3.0 part, Radix Et Rhizoma Rhei 0.1-1.0 part, Radix Glycyrrhizae 0.3-3.0 part, Semen Lepidii (Semen Descurainiae) 0.2-1.5 part, Semen Armeniacae Amarum 0.2-1.5 part, Herba Schizonepetae 0.2-1.5 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3-3.0 part, Cortex Phellodendri 0.2-1.5 part and Periostracum Cicadae 0.2-1.5 part will be taken by weight;
Parch step: described Semen Armeniacae Amarum, described Concha Ostreae, described Radix Et Rhizoma Rhei, described Semen Lepidii (Semen Descurainiae) are fried black respectively; And be pulverized and mixed step.
Further, in preferred embodiment of the present invention, above-mentioned material preparation step also comprises pre-treatment step, and described pre-treatment step comprises removes described Semen Armeniacae Amarum skin zone and tail tip.
Further, in preferred embodiment of the present invention, above-mentioned material preparation step also comprises and takes Semen Plantaginis 0.2-1.5 part, Radix Saposhnikoviae 0.06-0.6 part, Bombyx Batryticatus 0.1-1.0 part and Endoconcha Sepiae 0.2-1.5 part by weight.
Further, in preferred embodiment of the present invention, above-mentioned parch step also comprises sifting step, described in the scope of sieving be 60 order-200 orders.
Further, in preferred embodiment of the present invention, above-mentioned pulverising step comprises at least three pulverizing, and first time is crushed to 60 orders, and second time is crushed to 120 orders, and third time is crushed to 200 orders.
Further, in preferred embodiment of the present invention, the method pulverized in above-mentioned pulverising step comprises chopping or smashes.
The beneficial effect of the Chinese powder medicine of the control animal retention toxicosis of the embodiment of the present invention and preparation method thereof is: count by weight due to Chinese powder medicine and comprise Radix Bupleuri 0.5-4.5 part, Radix Scutellariae 0.5-4.5 part, Ramulus Cinnamomi 0.5-4.0 part, Rhizoma Zingiberis 0.3-3.0 part, Radix Trichosanthis 0.5-4.5 part, Concha Ostreae 0.3-3.0 part, Radix Et Rhizoma Rhei 0.1-1.0 part, Radix Glycyrrhizae 0.3-3.0 part, Semen Lepidii (Semen Descurainiae) 0.2-1.5 part, Semen Armeniacae Amarum 0.2-1.5 part, Herba Schizonepetae 0.2-1.5 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3-3.0 part, Cortex Phellodendri 0.2-1.5 part, and Periostracum Cicadae 0.2-1.5 part, therefore the lesions of liver and kidney that animal is caused because of retention toxicosis can well be repaired, improve animal livers detoxification ability and kidney toxin expelling ability, simultaneously, this Chinese powder medicine all has the function of good detoxication and toxicant eliminating function for the mycotoxin entered in animal body, medicine, heavy metal, bacterial endotoxin etc., the various toxin in animal body can be removed more thoroughly, reduce the adverse effect that various toxin produces the aspect such as physiological status, fertility performance of animal.
Detailed description of the invention
For making the object of the embodiment of the present invention, technical scheme and advantage clearly, be clearly and completely described to the technical scheme in the embodiment of the present invention below.Unreceipted actual conditions person in embodiment, the condition of conveniently conditioned disjunction manufacturer suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, be and can buy by commercially available the conventional products obtained.
Below the compound of the embodiment of the present invention and the processing technology of compound are specifically described.
The Chinese powder medicine of the control animal retention toxicosis that the embodiment of the present invention provides, comprises the following composition counted by weight:
Radix Bupleuri 0.5-4.5 part, Radix Scutellariae 0.5-4.5 part, Ramulus Cinnamomi 0.5-4.0 part, Rhizoma Zingiberis 0.3-3.0 part, Radix Trichosanthis 0.5-4.5 part, Concha Ostreae 0.3-3.0 part, Radix Et Rhizoma Rhei 0.1-1.0 part, Radix Glycyrrhizae 0.3-3.0 part, Semen Lepidii (Semen Descurainiae) 0.2-1.5 part, Semen Armeniacae Amarum 0.2-1.5 part, Herba Schizonepetae 0.2-1.5 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3-3.0 part, Cortex Phellodendri 0.2-1.5 part and Periostracum Cicadae 0.2-1.5 part.
This Chinese powder medicine, carries out compatibility according to the principles of formulating prescriptions of monarch:
Monarch drug is Radix Bupleuri, Radix Scutellariae, Ramulus Cinnamomi, and wherein effect of Radix Bupleuri is elevate a turnable ladder yang-energy, and effect of Radix Scutellariae is for removing gallbladder-heat, and effect of Ramulus Cinnamomi is warming the meridian and promoting blood circulation, supporing yang activating QI;
Ministerial drug: Rhizoma Zingiberis, Concha Ostreae, Radix Et Rhizoma Rhei, Radix Trichosanthis, wherein Rhizoma Zingiberis energy warming the stomach, relax lung, Radix Et Rhizoma Rhei energy laxation, pushes away Chen Zhixin, Radix Trichosanthis and Concha Ostreae energy tonifying kidney-yin, remuval of damp and hot.
Make medicine, adjuvant drug: Radix Glycyrrhizae, Herba Schizonepetae, Rhizoma Atractylodis Macrocephalae (parched), Cortex Phellodendri, Periostracum Cicadae, Semen Lepidii (Semen Descurainiae), Semen Armeniacae Amarum, Radix Saposhnikoviae, Semen Plantaginis, Bombyx Batryticatus, Endoconcha Sepiae, wherein Radix Glycyrrhizae can neutralize all medicines, Herba Schizonepetae can be had one's ideas straightened out, Rhizoma Atractylodis Macrocephalae (parched) energy warming the stomach, dampness, the clear damp-heat in lower-JIAO of Cortex Phellodendri energy, Periostracum Cicadae can be dispeled the wind, and Semen Lepidii (Semen Descurainiae) and Semen Armeniacae Amarum can remove lung-heat.
Preferably, the Chinese powder medicine preventing and treating animal retention toxicosis also comprises the following composition counted by weight: Semen Plantaginis 0.2-1.5 part, Radix Saposhnikoviae 0.06-0.6 part, Bombyx Batryticatus 0.1-1.0 part and Endoconcha Sepiae 0.2-1.5 part.
Wherein, anti-wind energy is dispeled the wind; The diuresis of Semen Plantaginis energy, heat clearing away; Bombyx Batryticatus can be dispelled lung-wind syndrome; Endoconcha Sepiae can control gastritis.After the above-mentioned four taste Chinese medicines of increase, the drug effect of this Chinese powder medicine control animal retention toxicosis is better.
The preparation method of the Chinese powder medicine of the control animal retention toxicosis that the embodiment of the present invention provides, comprises the steps:
1) material preparation step: Radix Bupleuri 0.5-4.5 part, Radix Scutellariae 0.5-4.5 part, Ramulus Cinnamomi 0.5-4.0 part, Rhizoma Zingiberis 0.3-3.0 part, Radix Trichosanthis 0.5-4.5 part, Concha Ostreae 0.3-3.0 part, Radix Et Rhizoma Rhei 0.1-1.0 part, Radix Glycyrrhizae 0.3-3.0 part, Semen Lepidii (Semen Descurainiae) 0.2-1.5 part, Semen Armeniacae Amarum 0.2-1.5 part, Herba Schizonepetae 0.2-1.5 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3-3.0 part, Cortex Phellodendri 0.2-1.5 part and Periostracum Cicadae 0.2-1.5 part will be taken by weight.
In the material preparation step preparing Chinese powder medicine, preferably pre-treatment step is carried out to Semen Armeniacae Amarum, Semen Armeniacae Amarum has bitter temperature lung qi dispersing, effect of loosening bowel to relieve constipation, because Semen Armeniacae Amarum is slightly poisonous, the toxicity of its skin zone and tail tip is comparatively large, and therefore Semen Armeniacae Amarum removes skin zone and the tail tip of Semen Armeniacae Amarum before stir-fry is black, further can ensure drug safety.
2) parch step: described Semen Armeniacae Amarum, described Concha Ostreae, described Radix Et Rhizoma Rhei, described Semen Lepidii (Semen Descurainiae) are fried black respectively.
In the parch step preparing Chinese powder medicine, Semen Armeniacae Amarum, Concha Ostreae, Radix Et Rhizoma Rhei, Semen Lepidii (Semen Descurainiae) fry respectively black object be change its drug effect, make its with other medical material compatibility in prescription after, the drug effect of this Chinese powder medicine is stronger.Wherein, after Concha Ostreae stir-fry is black, its function becomes the effect of remuval of damp and hot from diuretic effect; After Radix Et Rhizoma Rhei stir-fry is black, its function becomes the effect of laxation, antiinflammatory by discharge function; After the stir-fry of Semen Lepidii (Semen Descurainiae), Semen Armeniacae Amarum is black, its function becomes lung heat clearing heat in the interior by lung heat clearing sun thermal change.
3) step is pulverized and mixed.
In the parch step preparing Chinese powder medicine, the medical material in prescription needs to be pulverized and mixed by weight.If medical material amount is large, the mix homogeneously by weight again after first pulverizing one by one of the medical material in prescription, the benefit done like this is the mixed pulverizing difficulty of medical material reducing differing texture, makes it mix more even; If medical material amount is few, the medical material in prescription by weight after mix homogeneously, then is pulverized, and the benefit done like this is to reduce manufacturing procedure, reduces cost.
Be pulverized and mixed in step what prepare Chinese powder medicine, because the pulverizing medicinal materials difficulty of differing texture is different, preferably, adopts at least three disintegrating process, adopt and can reduce pulverizing difficulty in this way, make it mix more even.When preparing this Chinese powder medicine, in pulverizer, carry out coarse powder after first being mixed by medical material, after being crushed to 60 orders for the first time, replaceability can better carry out second time pulverizing by pulverizer, is crushed to 120 orders, finally, carry out third time again to pulverize, be crushed to 200 orders, each medical material is mixed fully.
Be pulverized and mixed in step what prepare Chinese powder medicine, the method for grinding medicinal materials is preferably shredded or smashes.The mode of chopping that what general powder beater adopted is, can by the processing of crude drugs powdered of lamellar or bulk, and the mode of this pulverizing is simple to operate, easily realizes; And adopt the mode smashed, the cell wall rupture of medical material can be made, increase the dissolution rate of effective ingredient in medical material, thus further improve drug effect.
The Chinese powder medicine of this control animal retention toxicosis may be used for many animals, such as chicken, cattle, pig, sheep etc.
Below in conjunction with embodiment, characteristic sum performance of the present invention is described in further detail.
Embodiment 1
The Chinese powder medicine of the control animal retention toxicosis of the present embodiment, comprises the following composition counted by weight:
Radix Bupleuri 1.5 parts, Radix Scutellariae 1.5 parts, Ramulus Cinnamomi 1.5 parts, Rhizoma Zingiberis 1.0 parts, Radix Trichosanthis 1.2 parts, Concha Ostreae 1.0 parts, Radix Et Rhizoma Rhei 0.3 part, 0.8 part, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 0.5 part, 0.5 part, Semen Armeniacae Amarum, Herba Schizonepetae 0.5 part, Rhizoma Atractylodis Macrocephalae (parched) 1.0 parts, Cortex Phellodendri 0.5 part and Periostracum Cicadae 0.5 part.
The preparation method of the Chinese powder medicine of above-mentioned control animal retention toxicosis, concrete preparation process is as follows:
First, Radix Bupleuri 1.5 parts, Radix Scutellariae 1.5 parts, Ramulus Cinnamomi 1.5 parts, Rhizoma Zingiberis 1.0 parts, Radix Trichosanthis 1.2 parts, Concha Ostreae 1.0 parts, Radix Et Rhizoma Rhei 0.3 part, 0.8 part, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 0.5 part, 0.5 part, Semen Armeniacae Amarum, Herba Schizonepetae 0.5 part, Rhizoma Atractylodis Macrocephalae (parched) 1.0 parts, Cortex Phellodendri 0.5 part and Periostracum Cicadae 0.5 part will be taken by weight.
Especially, Semen Armeniacae Amarum skin zone and tail tip is removed.
Then, above-mentioned Semen Armeniacae Amarum, described Concha Ostreae, described Radix Et Rhizoma Rhei, described Semen Lepidii (Semen Descurainiae) are fried black respectively.
Then, above-mentioned medical material is pulverized one by one in powder beater, and the above-mentioned medicinal powder after pulverizing is crossed 200 mesh sieves.Afterwards by the above-mentioned medicinal powder mix homogeneously after sieving, to obtain final product.
Sifting step: above-mentioned medicinal powder is crossed 200 mesh sieves;
Blend step: by above-mentioned medicinal powder mix homogeneously, to obtain final product.
Embodiment 2
The Chinese powder medicine of the control animal retention toxicosis of the present embodiment, comprises the following composition counted by weight:
Radix Bupleuri 1.5 parts, Radix Scutellariae 1.5 parts, Ramulus Cinnamomi 1.5 parts, Rhizoma Zingiberis 1.0 parts, Radix Trichosanthis 1.2 parts, Concha Ostreae 1.0 parts, Radix Et Rhizoma Rhei 0.3 part, 0.8 part, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 0.5 part, 0.5 part, Semen Armeniacae Amarum, Herba Schizonepetae 0.5 part, Rhizoma Atractylodis Macrocephalae (parched) 1.0 parts, Cortex Phellodendri 0.5 part, Periostracum Cicadae 0.5 part, Semen Plantaginis 0.5 part, Radix Saposhnikoviae 0.2 part, Bombyx Batryticatus 0.3 part and Endoconcha Sepiae 0.5 part.
The preparation method of the Chinese powder medicine of above-mentioned control animal retention toxicosis, concrete preparation process is as follows:
First, Radix Bupleuri 1.5 parts, Radix Scutellariae 1.5 parts, Ramulus Cinnamomi 1.5 parts, Rhizoma Zingiberis 1.0 parts, Radix Trichosanthis 1.2 parts, Concha Ostreae 1.0 parts, Radix Et Rhizoma Rhei 0.3 part, 0.8 part, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 0.5 part, 0.5 part, Semen Armeniacae Amarum, Herba Schizonepetae 0.5 part, Rhizoma Atractylodis Macrocephalae (parched) 1.0 parts, Cortex Phellodendri 0.5 part, Periostracum Cicadae 0.5 part, Semen Plantaginis 0.5 part, Radix Saposhnikoviae 0.2 part, Bombyx Batryticatus 0.3 part and Endoconcha Sepiae 0.5 part will be taken by weight.
Especially, Semen Armeniacae Amarum skin zone and tail tip is removed.
Then, above-mentioned Semen Armeniacae Amarum, described Concha Ostreae, described Radix Et Rhizoma Rhei, described Semen Lepidii (Semen Descurainiae) are fried black respectively;
Then, by above-mentioned medical material mix homogeneously, and in powder beater, adopted by mixed medical material three comminuting methods to pulverize, first time is crushed to 60 orders, and second time is crushed to 120 orders, adopts the method smashed to be crushed to 200 orders, mix homogeneously for the third time, to obtain final product.
Embodiment 3
The Chinese powder medicine of the control animal retention toxicosis of the present embodiment, comprises the following composition counted by weight:
Radix Bupleuri 0.5 part, Radix Scutellariae 0.5 part, Ramulus Cinnamomi 0.5 part, Rhizoma Zingiberis 0.3 part, Radix Trichosanthis 0.5 part, Concha Ostreae 0.3 part, Radix Et Rhizoma Rhei 0.1 part, 0.3 part, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 0.2 part, 0.2 part, Semen Armeniacae Amarum, Herba Schizonepetae 0.2 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3 part, Cortex Phellodendri 0.2 part and Periostracum Cicadae 0.2 part.
The preparation method of the Chinese powder medicine of above-mentioned control animal retention toxicosis, concrete preparation process is as follows:
First, Radix Bupleuri 0.5 part, Radix Scutellariae 0.5 part, Ramulus Cinnamomi 0.5 part, Rhizoma Zingiberis 0.3 part, Radix Trichosanthis 0.5 part, Concha Ostreae 0.3 part, Radix Et Rhizoma Rhei 0.1 part, 0.3 part, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 0.2 part, 0.2 part, Semen Armeniacae Amarum, Herba Schizonepetae 0.2 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3 part, Cortex Phellodendri 0.2 part and Periostracum Cicadae 0.2 part will be taken by weight.
Especially, Semen Armeniacae Amarum skin zone and tail tip is removed.
Then, above-mentioned Semen Armeniacae Amarum, described Concha Ostreae, described Radix Et Rhizoma Rhei, described Semen Lepidii (Semen Descurainiae) are fried black respectively.
Then, above-mentioned medical material is pulverized one by one in powder beater, and above-mentioned medicinal powder is crossed 200 mesh sieves.Afterwards, by the above-mentioned medicinal powder mix homogeneously after sieving, to obtain final product.
Embodiment 4
The Chinese powder medicine of the control animal retention toxicosis of the present embodiment, comprises the following composition counted by weight:
Radix Bupleuri 0.5 part, Radix Scutellariae 0.5 part, Ramulus Cinnamomi 0.5 part, Rhizoma Zingiberis 0.3 part, Radix Trichosanthis 0.5 part, Concha Ostreae 0.3 part, Radix Et Rhizoma Rhei 0.1 part, 0.3 part, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 0.2 part, 0.2 part, Semen Armeniacae Amarum, Herba Schizonepetae 0.2 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3 part, Cortex Phellodendri 0.2 part, Periostracum Cicadae 0.2 part, Semen Plantaginis 0.2 part, Radix Saposhnikoviae 0.06 part, Bombyx Batryticatus 0.1 part and Endoconcha Sepiae 0.2 part.
The preparation method of the Chinese powder medicine of above-mentioned control animal retention toxicosis, concrete preparation process is as follows:
First, Radix Bupleuri 0.5 part, Radix Scutellariae 0.5 part, Ramulus Cinnamomi 0.5 part, Rhizoma Zingiberis 0.3 part, Radix Trichosanthis 0.5 part, Concha Ostreae 0.3 part, Radix Et Rhizoma Rhei 0.1 part, 0.3 part, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 0.2 part, 0.2 part, Semen Armeniacae Amarum, Herba Schizonepetae 0.2 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3 part, Cortex Phellodendri 0.2 part, Periostracum Cicadae 0.2 part, Semen Plantaginis 0.2 part, Radix Saposhnikoviae 0.06 part, Bombyx Batryticatus 0.1 part and Endoconcha Sepiae 0.2 part will be taken by weight.
Especially, Semen Armeniacae Amarum skin zone and tail tip is removed;
Then, above-mentioned Semen Armeniacae Amarum, described Concha Ostreae, described Radix Et Rhizoma Rhei, described Semen Lepidii (Semen Descurainiae) are fried black respectively;
Then, after above-mentioned medical material mix homogeneously, in powder beater, adopt three comminuting methods to pulverize, first time is crushed to 60 orders, and second time is crushed to 120 orders, adopts the method smashed to be crushed to 200 orders for the third time, to obtain final product.
Embodiment 5,
The Chinese powder medicine of the control animal retention toxicosis of the present embodiment, comprises the following composition counted by weight:
Radix Bupleuri 4.5 parts, Radix Scutellariae 4.5 parts, Ramulus Cinnamomi 4.0 parts, Rhizoma Zingiberis 3.0 parts, Radix Trichosanthis 4.5 parts, Concha Ostreae 3.0 parts, Radix Et Rhizoma Rhei 1.0 parts, 3.0 parts, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 1.5 parts, 1.5 parts, Semen Armeniacae Amarum, Herba Schizonepetae 1.5 parts, Rhizoma Atractylodis Macrocephalae (parched) 3.0 parts, Cortex Phellodendri 1.5 parts and Periostracum Cicadae 1.5 parts.
The preparation method of the Chinese powder medicine of above-mentioned control animal retention toxicosis, concrete preparation process is as follows:
First, Radix Bupleuri 4.5 parts, Radix Scutellariae 4.5 parts, Ramulus Cinnamomi 4.0 parts, Rhizoma Zingiberis 3.0 parts, Radix Trichosanthis 4.5 parts, Concha Ostreae 3.0 parts, Radix Et Rhizoma Rhei 1.0 parts, 3.0 parts, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 1.5 parts, 1.5 parts, Semen Armeniacae Amarum, Herba Schizonepetae 1.5 parts, Rhizoma Atractylodis Macrocephalae (parched) 3.0 parts, Cortex Phellodendri 1.5 parts and Periostracum Cicadae 1.5 parts will be taken by weight.
Then, above-mentioned Semen Armeniacae Amarum, described Concha Ostreae, described Radix Et Rhizoma Rhei, described Semen Lepidii (Semen Descurainiae) are fried black respectively.
Then, above-mentioned medical material is pulverized one by one in powder beater, and above-mentioned medicinal powder mix homogeneously, to obtain final product.
Embodiment 6,
The Chinese powder medicine of the control animal retention toxicosis of the present embodiment, comprises the following composition counted by weight:
Radix Bupleuri 4.5 parts, Radix Scutellariae 4.5 parts, Ramulus Cinnamomi 4.0 parts, Rhizoma Zingiberis 3.0 parts, Radix Trichosanthis 4.5 parts, Concha Ostreae 3.0 parts, Radix Et Rhizoma Rhei 1.0 parts, 3.0 parts, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 1.5 parts, 1.5 parts, Semen Armeniacae Amarum, Herba Schizonepetae 1.5 parts, Rhizoma Atractylodis Macrocephalae (parched) 3.0 parts, Cortex Phellodendri 1.5 parts, Periostracum Cicadae 1.5 parts, Semen Plantaginis 1.5 parts, Radix Saposhnikoviae 0.6 part, Bombyx Batryticatus 1.0 parts, Endoconcha Sepiae 1.5 parts.
The preparation method of the Chinese powder medicine of above-mentioned control animal retention toxicosis, concrete preparation process is as follows:
First, Radix Bupleuri 4.5 parts, Radix Scutellariae 4.5 parts, Ramulus Cinnamomi 4.0 parts, Rhizoma Zingiberis 3.0 parts, Radix Trichosanthis 4.5 parts, Concha Ostreae 3.0 parts, Radix Et Rhizoma Rhei 1.0 parts, 3.0 parts, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae) 1.5 parts, 1.5 parts, Semen Armeniacae Amarum, Herba Schizonepetae 1.5 parts, Rhizoma Atractylodis Macrocephalae (parched) 3.0 parts, Cortex Phellodendri 1.5 parts, Periostracum Cicadae 1.5 parts, Semen Plantaginis 1.5 parts, Radix Saposhnikoviae 0.6 part, Bombyx Batryticatus 1.0 parts, Endoconcha Sepiae 1.5 parts will be taken by weight.
Then, above-mentioned Semen Armeniacae Amarum, described Concha Ostreae, described Radix Et Rhizoma Rhei, described Semen Lepidii (Semen Descurainiae) are fried black respectively.
Then, after above-mentioned medical material mix homogeneously, in powder beater, adopt three comminuting methods to pulverize, first time is crushed to 60 orders, and second time is crushed to 120 orders, adopts the method smashed to be crushed to 200 orders for the third time.
Embodiment 7,
The prescription of this Chinese powder medicine is Radix Bupleuri, Radix Scutellariae, Ramulus Cinnamomi, Rhizoma Zingiberis, Radix Trichosanthis, Concha Ostreae, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Semen Lepidii (Semen Descurainiae), Semen Armeniacae Amarum, Herba Schizonepetae, Rhizoma Atractylodis Macrocephalae (parched), Cortex Phellodendri, Periostracum Cicadae.Chinese medicinal formulae in the present invention carries out dialectical to animal retention toxicosis, in conjunction with theory of Chinese medical science, releases the rule for the treatment of, forms prescription.This Chinese powder medicine well can repair the lesions of liver and kidney of the animal of retention toxicosis, improves liver detoxification ability and the kidney toxin expelling ability of animal.
Can illustrate that the experimentation of beneficial effect of the present invention is as follows:
This experiment take laying hen as experimental subject, choose weight and health status consistent 360 ages in days sea blue grey laying hens 600, be divided into three groups at random, often organize 200 laying hens, one group is matched group, and another two groups are respectively experiment one group and experiment two groups, control group fed basal diet, test the Chinese powder medicine being added with the present embodiment 1 gained in one group of basal diet of feeding, test the Chinese powder medicine being added with the present embodiment 2 gained in two groups of basal diets of feeding.In the feedstuff of experiment one group with experiment two groups, the mass ratio of the Chinese powder medicine of basal diet and interpolation is 200:1.The feeding and management method of these three groups of laying hens is identical, adopts test chicken staged to raise in cages, unified light regime, full phase free choice feeding and drinking-water.Test one group and experiment to be fed the above-mentioned basal diet being added with Chinese powder medicine two groups of continuous 10 days of every months, be used in conjunction 2 times, basal diet of feeding At All Other Times, matched group whole process is fed basal diet, duration of experiment two months.
(60d) morning when (0d) and off-test before the test, often organize and randomly draw 10 chickens respectively, Culling heart blood is about 3-5 milliliter, 4 DEG C of centrifugal (3000r/min, 20min), separation of serum, puts-20 DEG C of Refrigerator stores, delivers to 309 hospital laboratories and detect glutamate pyruvate transaminase under condition of ice bath, glutamic oxaloacetic transaminase, GOT, total protein, albumin, alkali phosphatase 5 indexs; Duration of test records egg number, egg quality, broken soft egg number, dead naughty chicken number every day respectively.
Experimental result:
1. results of serum biochemical detection is as table 1
Table 1: Chinese powder medicine of the present invention is on the impact of laying hen blood physiological and biochemical indices
As known from Table 1 matched group, test one group and the experiment experiment laying hen of two groups exists hepar damnification, the Chinese powder medicine adding embodiments of the invention 1 and embodiment 2 gained in feedstuff significantly can reduce the content (p<0.05) of glutamic oxaloacetic transaminase, GOT in serum and glutamate pyruvate transaminase, the Chinese medicinal formulae disclosed in the present invention can repair hepar damnification, improves liver function.The total protein levels of testing two groups is significantly increased (p<0.05) relative to matched group, but albumin level compares zero difference, illustrate after using Chinese powder medicine of the present invention, globulin levels in laying hen body (globulin=total protein-albumin) can be significantly improved, disclose the immunocompetence that Chinese powder medicine of the present invention can improve laying hen.
2. performance in layers result is as table 2
Table 2 performance in layers difference
The Chinese powder medicine adding embodiments of the invention 1 and embodiment 2 as known from Table 2 in feed diet can significantly improve laying rate (p<0.05), reduce broken soft egg rate (p<0.05), death rate (p<0.05).
In sum, the Chinese powder medicine in the present invention can repair the lesions of liver and kidney that animal is caused because of retention toxicosis very well, improves animal livers detoxification ability and kidney toxin expelling ability; Simultaneously, this Chinese powder medicine all has the function of good detoxication and toxicant eliminating function for the mycotoxin entered in animal body, medicine, heavy metal, bacterial endotoxin etc., the various toxin in animal body can be removed more thoroughly, reduce the adverse effect that various toxin produces the aspect such as physiological status, fertility performance of animal.
Embodiment described above is the present invention's part embodiment, instead of whole embodiments.The detailed description of embodiments of the invention the claimed scope of the present invention of not intended to be limiting, but only represent selected embodiment of the present invention.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.

Claims (10)

1. prevent and treat a Chinese powder medicine for animal retention toxicosis, it is characterized in that, described Chinese powder medicine is counted by weight and is comprised:
Radix Bupleuri 0.5-4.5 part, Radix Scutellariae 0.5-4.5 part, Ramulus Cinnamomi 0.5-4.0 part, Rhizoma Zingiberis 0.3-3.0 part, Radix Trichosanthis 0.5-4.5 part, Concha Ostreae 0.3-3.0 part, Radix Et Rhizoma Rhei 0.1-1.0 part, Radix Glycyrrhizae 0.3-3.0 part, Semen Lepidii (Semen Descurainiae) 0.2-1.5 part, Semen Armeniacae Amarum 0.2-1.5 part, Herba Schizonepetae 0.2-1.5 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3-3.0 part, Cortex Phellodendri 0.2-1.5 part and Periostracum Cicadae 0.2-1.5 part.
2. the Chinese powder medicine of control animal retention toxicosis according to claim 1, it is characterized in that, described Chinese powder medicine is counted by weight and is also comprised: Semen Plantaginis 0.2-1.5 part, Radix Saposhnikoviae 0.06-0.6 part, Bombyx Batryticatus 0.1-1.0 part and Endoconcha Sepiae 0.2-1.5 part.
3. the Chinese powder medicine of control animal retention toxicosis according to claim 1 and 2, it is characterized in that, described Radix Bupleuri is 1.5 parts, described Radix Scutellariae is 1.5 parts, described Ramulus Cinnamomi is 1.5 parts, described Rhizoma Zingiberis is 1.0 parts, described Radix Trichosanthis is 1.2 parts, described Concha Ostreae is 1.0 parts, described Radix Et Rhizoma Rhei for for 0.3 part, described Radix Glycyrrhizae is 0.8 part, described Semen Lepidii (Semen Descurainiae) is 0.5 part, described Semen Armeniacae Amarum is 0.5 part, described Herba Schizonepetae is 0.5 part, described Rhizoma Atractylodis Macrocephalae (parched) is 1.0 parts, described Cortex Phellodendri be 0.5 part and described Periostracum Cicadae is 0.5 part.
4. the Chinese powder medicine of control animal retention toxicosis according to claim 3, is characterized in that, described Semen Plantaginis is 0.5 part, described Radix Saposhnikoviae is 0.2 part, described Bombyx Batryticatus is 0.3 part, described Endoconcha Sepiae is 0.5 part.
5. prevent and treat a preparation method for the Chinese powder medicine of animal retention toxicosis, it is characterized in that, it comprises:
Material preparation step: take Radix Bupleuri 0.5-4.5 part, Radix Scutellariae 0.5-4.5 part, Ramulus Cinnamomi 0.5-4.0 part, Rhizoma Zingiberis 0.3-3.0 part, Radix Trichosanthis 0.5-4.5 part, Concha Ostreae 0.3-3.0 part, Radix Et Rhizoma Rhei 0.1-1.0 part, Radix Glycyrrhizae 0.3-3.0 part, Semen Lepidii (Semen Descurainiae) 0.2-1.5 part, Semen Armeniacae Amarum 0.2-1.5 part, Herba Schizonepetae 0.2-1.5 part, Rhizoma Atractylodis Macrocephalae (parched) 0.3-3.0 part, Cortex Phellodendri 0.2-1.5 part and Periostracum Cicadae 0.2-1.5 part by weight;
Parch step: described Semen Armeniacae Amarum, described Concha Ostreae, described Radix Et Rhizoma Rhei, described Semen Lepidii (Semen Descurainiae) are fried black respectively; And
Be pulverized and mixed step.
6. the preparation method of the Chinese powder medicine of control animal retention toxicosis according to claim 5, is characterized in that, also comprise pre-treatment step at described material preparation step, and described pre-treatment step comprises removes described Semen Armeniacae Amarum skin zone and tail tip.
7. the preparation method of the Chinese powder medicine of the control animal retention toxicosis according to claim 5 or 6, it is characterized in that, described material preparation step also comprises and takes described Semen Plantaginis 0.2-1.5 part, described Radix Saposhnikoviae 0.06-0.6 part, described Bombyx Batryticatus 0.1-1.0 part, described Endoconcha Sepiae 0.2-1.5 part by weight.
8. the preparation method of the Chinese powder medicine of control animal retention toxicosis according to claim 5, is characterized in that, also comprise sifting step, described in the scope of sieving be 60 order-200 orders.
9. the preparation method of the Chinese powder medicine of control animal retention toxicosis according to claim 8, it is characterized in that, described pulverising step comprises at least three pulverizing, and first time is crushed to 60 orders, and second time is crushed to 120 orders, and third time is crushed to 200 orders.
10. the preparation method of the Chinese powder medicine of control animal retention toxicosis according to claim 9, the method pulverized in described pulverising step comprises chopping or smashes.
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