CN104174005A - Medicine for treating hepatitis b cirrhosis - Google Patents
Medicine for treating hepatitis b cirrhosis Download PDFInfo
- Publication number
- CN104174005A CN104174005A CN201410468141.6A CN201410468141A CN104174005A CN 104174005 A CN104174005 A CN 104174005A CN 201410468141 A CN201410468141 A CN 201410468141A CN 104174005 A CN104174005 A CN 104174005A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- medicine
- rhizoma
- fry
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention provides a medicine for treating hepatitis b cirrhosis. The medicine is prepared from the following components: fructus evodiae, angelica sinensis, sichuan lovage rhizome, radix rehmanniae, radix paeoniae alba, cooked rhubarb, leech (prepared), gadfly (wings and feet removed, fried), scutellaria baicalensis, cassia twig, poria, roasted rhizoma atractylodis macrocephalae, peach kernel, bitter apricot kernel (fried), red ginseng, dried ginger, aconitum vilmorinianum kom and radix glycyrrhizae preparata. The medicine has the effects of nourishing yin and clearing heat, activating blood circulation to remove stasis, dredging channels and eliminating masses, can achieve the effect of treating both symptoms and root causes of hepatitis b cirrhosis and eliminating clinical symptoms to finally achieve the aim of healing. Furthermore, the medicine is combined by medicines with an inflammation-diminishing effect and medicines with effects of protecting liver, dredging channels and nourishing yin, and has an excellent effect on patients with hepatitis b cirrhosis in different courses. The medicine composition has a remarkable effect for treating hepatitis b cirrhosis and does not have side effect.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of hbv-liver cirrhosis.
Background technology
Liver cirrhosis is a kind of chronic hepatopathy that forms feature with the hepatic fibrosis of hepatic tissue diffusivity, pseudolobuli and regenerated nodule, is common clinically refractory disease, and mortality rate is high.In China, the common liver cirrhosis cause of disease is chronic viral hepatitis, especially chronic hepatitis B.The chronicity of viral hepatitis easily causes first dimension of liver, even the result of hepatic fibrosis chronic hepatitis, the pathology reason of development occurs busy liver cirrhosis.
At present, doctor trained in Western medicine mainly adopts antiviral and anti-hepatic fibrosis medicines to the treatment of hbv-liver cirrhosis, but its curative effect is scarce not fully up to expectations.
Summary of the invention
New and effective safe applicable to thrombocytopenic medicine for the treatment of caused by radiotherapy and chemotherapy and preparation method thereof for obtaining, the inventor through a large amount of further investigations, after having paid sufficient creative work, has completed the present invention to this.
For the etiology and pathogenesis of liver cirrhosis, the present invention adopts the medicine of removing pathogenic heat from blood and toxic substance from the body, anti-inflammatory analgesic, blood circulation promoting and blood stasis dispelling, replenishing QI to invigorate the spleen, yin nourishing diuretic to carry out determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.
The present invention relates to a kind of medicine for the treatment of hbv-liver cirrhosis, by Fructus Evodiae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Hirudo (system), Tabanus (remove wing foot, fry), Radix Scutellariae, Ramulus Cinnamomi, Poria, Rhizoma Atractylodis Macrocephalae (parched), Semen Persicae, Semen Armeniacae Amarum (stir-fry), Radix Ginseng Rubra, Rhizoma Zingiberis, yellow Radix Aconiti Lateralis Preparata, Radix Glycyrrhizae Preparata, formed.
As a kind of exemplary exemplifying, in described pharmaceutical composition, in weight portion, its concrete constituent content is as follows:
Fructus Evodiae 40-80 part, Radix Angelicae Sinensis 100-130 part, Rhizoma Chuanxiong 100-130 part, Radix Rehmanniae 280-320 part, Radix Paeoniae Alba 100-130 part, Radix Et Rhizoma Rhei 280-320 part, Hirudo (system) 40-80 part, Tabanus (remove wing foot, fry) 40-80 part, Radix Scutellariae 40-80 part, Ramulus Cinnamomi 100-130 part, Poria 100-140 part, Rhizoma Atractylodis Macrocephalae (parched) 40-80 part, Semen Persicae 100-140 part, Semen Armeniacae Amarum (stir-fry) 100-130 part, Radix Ginseng Rubra 110-120 part, Rhizoma Zingiberis 100-130 part, yellow Radix Aconiti Lateralis Preparata 40-80 part, Radix Glycyrrhizae Preparata 80-100 part.
Medicine of the present invention has optimum ratio to be:
Preferably, 60 parts of Fructus Evodiaes, 120 parts of Radix Angelicae Sinensis, 120 parts of Rhizoma Chuanxiong, 300 parts of Radix Rehmanniae, 120 parts of the Radix Paeoniae Albas, 300 parts of Radix Et Rhizoma Rhei, 60 parts of Hirudos (system), 60 parts of Tabanuss (remove wing foot, fry), 60 parts of Radix Scutellariaes, 120 parts of Ramulus Cinnamomi, 120 parts, Poria, 60 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 120 parts, Semen Persicae, 120 parts of Semen Armeniacae Amarums (stir-fry), 120 parts of Radix Ginseng Rubra, 120 parts of Rhizoma Zingiberiss, 60 parts of yellow Radix Aconiti Lateralis Preparatas, 90 parts of Radix Glycyrrhizae Preparata.
A kind of medicine for the treatment of hbv-liver cirrhosis as above, its preparation method is: 1), according to described weight portion, claim medicine, clear water soaked after 2 hours, adds the decocting 2.5～3.5 hours of 13～17 times of weight, filters centrifugal removing slag, and is condensed into clear paste; 2), by step 1) gained clear paste adds conventional adjuvant, according to technique, is prepared into syrup, electuary, tablet, the watered pill, honeyed pill etc.
Preferably, step 1) for adding the decocting 3 hours of 15 times of weight.
Decoction every day once.
Taboo: pungent, wine, life, food cool, really up to the mark, fried food, beverage, angry.
Wherein, the action and efficacy of main ingredient is:
Fructus Evodiae: enter liver, stomach warp, analgesia, antithrombotic form, antibacterial, antiviral, hepatoprotective effect.
Radix Angelicae Sinensis: sweet, pungent, temperature.Return liver, the heart, spleen channel.Enrich blood, promoting blood circulation and stopping pain, loosening bowel to relieve constipation.
Rhizoma Chuanxiong: return liver, gallbladder, heart channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.
Radix Rehmanniae: clearing away heat and cooling blood.
The Radix Paeoniae Alba: cool in nature, bitter in the mouth acid, is slightly cold, and has blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating.
Radix Et Rhizoma Rhei: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.
Hirudo (system): anticoagulation.
Tabanus: < < Compendium of Materia Medica detailed outline > >: Cheng Wuji cloud, hardship is walked blood, blood agglomeration is passerby not, with hardship, attacks it, therefore control blood-retention with Tabanus, be Liver Channel blood system medicine also.
Radix Scutellariae: be included into the heart, lung, gallbladder, large intestine channel, removing the relative excess fire, except damp and hot, hemostasis, antiabortive.Control high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tells, is defeated in battle, collapses, leaks, conjunctival congestion and swelling pain.
Ramulus Cinnamomi: its nature and flavor acrid, sweet, warm, enter lung, the heart, urinary bladder channel, be to cure mainly the conventional drugs for dispelling internal cold of interior cold, there is the effect of complement sun, promoting blood circulation, warming the spleen and stomach, normal and invigorating the liver and kidney medicine, medicine compatibility fills blood.
Poria: sweet, light, flat.GUIXIN, spleen, kidney channel, have promoting diuresis to eliminate damp pathogen, spleen invigorating, the effect of calming the nerves.
Rhizoma Atractylodis Macrocephalae (parched): sweet, hardship, temperature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, strengthening superficial resistance to stop perspiration.
Semen Persicae: < < Compendium of Materia Medica > >: main stasis migratory arthralgia, hectic fever due to YIN-deficiency, liver-malaria cold and heat, puerperal disorders of blood.
Semen Armeniacae Amarum: anti-inflammatory and antalgic.
Radix Ginseng Rubra: QI invigorating, YIN nourishing, beneficial blood, promote the production of body fluid, the effect such as heart tonifying, stomach invigorating, calmness.
Rhizoma Zingiberis: warming middle-JIAO is by cold, and recuperating depleted YANG is promoted blood circulation.
Radix Glycyrrhizae Preparata: spleen reinforcing stomach function regulating, Yiqi and vein recovery.
Beneficial effect of the present invention:
In conjunction with pharmacology and the property of medicine of above-mentioned raw materials medicine, through a large amount of research and Clinical Treatment Test repeatedly, develop medicine of the present invention, there is nourishing YIN and clearing away heat, promote blood circulation to disperse blood clot, the effect of dredge meridian and eliminate distention blood clot.Medicine of the present invention can reach the effect to hbv-liver cirrhosis treating both the principal and secondary aspects of a disease, eliminates clinical symptoms, finally reaches healing object.Simultaneously this medicine will have antiinflammation medicine and hepatoprotective, stimulate the menstrual flow, Yin-nourishing drug combines, and hepatitis B patient course of disease different times is all had to good result.Medicine composite for curing hbv-liver cirrhosis effect of the present invention significantly and have no side effect.
The specific embodiment
Below by specific embodiment, the present invention is described in detail; but the purposes of these exemplary embodiments and object are only used for exemplifying the present invention; not real protection scope of the present invention is formed to any type of any restriction, more non-protection scope of the present invention is confined to this.
Embodiment 1
Treat a medicine for hbv-liver cirrhosis, in weight portion, its concrete constituent content is as follows:
40 parts of Fructus Evodiaes, 100 parts of Radix Angelicae Sinensis, 100 parts of Rhizoma Chuanxiong, 280 parts of Radix Rehmanniae, 100 parts of the Radix Paeoniae Albas, 280 parts of Radix Et Rhizoma Rhei, 40 parts of Hirudos (system), 40 parts of Tabanuss (remove wing foot, fry), 40 parts of Radix Scutellariaes, 100 parts of Ramulus Cinnamomi, 100 parts, Poria, 40 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 100 parts, Semen Persicae, 100 parts of Semen Armeniacae Amarums (stir-fry), 110 parts of Radix Ginseng Rubra, 100 parts of Rhizoma Zingiberiss, 40 parts of yellow Radix Aconiti Lateralis Preparatas, 80 parts of Radix Glycyrrhizae Preparata.
Concrete preparation method is as follows:
1), according to described weight portion, claim medicine, clear water soaked after 2 hours, added the decocting 2.5～3.5 hours of 13～17 times of weight, filtered centrifugal removing slag, and was condensed into clear paste; 2), by step 1) gained clear paste adds conventional adjuvant, according to technique, is prepared into syrup, electuary, tablet, the watered pill, honeyed pill etc.
Embodiment 2
Treat a medicine for hbv-liver cirrhosis, in described pharmaceutical composition, in weight portion, its concrete constituent content is as follows:
80 parts of Fructus Evodiaes, 130 parts of Radix Angelicae Sinensis, 130 parts of Rhizoma Chuanxiong, 320 parts of Radix Rehmanniae, 130 parts of the Radix Paeoniae Albas, 320 parts of Radix Et Rhizoma Rhei, 80 parts of Hirudos (system), 80 parts of Tabanuss (remove wing foot, fry), 80 parts of Radix Scutellariaes, 130 parts of Ramulus Cinnamomi, 140 parts, Poria, 80 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 140 parts, Semen Persicae, 130 parts of Semen Armeniacae Amarums (stir-fry), 120 parts of Radix Ginseng Rubra, 130 parts of Rhizoma Zingiberiss, 80 parts of yellow Radix Aconiti Lateralis Preparatas, 100 parts of Radix Glycyrrhizae Preparata.Concrete preparation method is as follows:
With embodiment 1.
Embodiment 3
Treat a medicine for hbv-liver cirrhosis, in described pharmaceutical composition, in weight portion, its concrete constituent content is as follows:
50 parts of Fructus Evodiaes, 110 parts of Radix Angelicae Sinensis, 110 parts of Rhizoma Chuanxiong, 290 parts of Radix Rehmanniae, 110 parts of the Radix Paeoniae Albas, 290 parts of Radix Et Rhizoma Rhei, 50 parts of Hirudos (system), 50 parts of Tabanuss (remove wing foot, fry), 50 parts of Radix Scutellariaes, 110 parts of Ramulus Cinnamomi, 110 parts, Poria, 50 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 110 parts, Semen Persicae, 110 parts of Semen Armeniacae Amarums (stir-fry), 110 parts of Radix Ginseng Rubra, 110 parts of Rhizoma Zingiberiss, 60 parts of yellow Radix Aconiti Lateralis Preparatas, 90 parts of Radix Glycyrrhizae Preparata.
Concrete preparation method is as follows:
With embodiment 1.
Embodiment 4
Treat a medicine for hbv-liver cirrhosis, in described pharmaceutical composition, in weight portion, its concrete constituent content is as follows:
70 parts of Fructus Evodiaes, 120 parts of Radix Angelicae Sinensis, 120 parts of Rhizoma Chuanxiong, Radix Rehmanniae 280-320 part, 120 parts of the Radix Paeoniae Albas, 310 parts of Radix Et Rhizoma Rhei, 70 parts of Hirudos (system), 70 parts of Tabanuss (remove wing foot, fry), 70 parts of Radix Scutellariaes, 120 parts of Ramulus Cinnamomi, 130 parts, Poria, 70 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 130 parts, Semen Persicae, 120 parts of Semen Armeniacae Amarums (stir-fry), 120 parts of Radix Ginseng Rubra, 120 parts of Rhizoma Zingiberiss, 70 parts of yellow Radix Aconiti Lateralis Preparatas, 90 parts of Radix Glycyrrhizae Preparata.
Concrete preparation method is as follows:
With embodiment 1.
Embodiment 5
Treat a medicine for hbv-liver cirrhosis, in described pharmaceutical composition, in weight portion, its concrete constituent content is as follows:
60 parts of Fructus Evodiaes, 120 parts of Radix Angelicae Sinensis, 120 parts of Rhizoma Chuanxiong, 300 parts of Radix Rehmanniae, 120 parts of the Radix Paeoniae Albas, 300 parts of Radix Et Rhizoma Rhei, 60 parts of Hirudos (system), 60 parts of Tabanuss (remove wing foot, fry), 60 parts of Radix Scutellariaes, 120 parts of Ramulus Cinnamomi, 120 parts, Poria, 60 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 120 parts, Semen Persicae, 120 parts of Semen Armeniacae Amarums (stir-fry), 120 parts of Radix Ginseng Rubra, 120 parts of Rhizoma Zingiberiss, 60 parts of yellow Radix Aconiti Lateralis Preparatas, 90 parts of Radix Glycyrrhizae Preparata.
Concrete preparation method is as follows:
With embodiment 1.
Case and clinical effectiveness:
Case 1:
Leaf, female, 73 years old, examined in July, 2013, and main suit's abdominal distention, weak is become thin, both sides of the chest distending pain.Clinical main physical signs: abdomen is grand, soft, without tenderness, hepatic region is without button pain, liver palm, yellow urine, sign of ascites is positive, and purplish tongue is dark, stringy pulse, chemical examination liver function is undesired, and paddy third, glutamic oxaloacetic transaminase, GOT are respectively 357 and 477.4; Total protein 62.0; Albumin is 35.0, globulin 27.0; Bilirubin direct 6.4, total bilirubin 12.6.Hepatitis B virus surface antigen is positive, surface antibody is positive, core antibody positive, and Type B color doppler ultrasonic checks: liver volume form is roughly dwindled, rough, liver parenchyma echo unshapeliness, portal vein diameter 15mm, extrahepatic duct has no expansion.Splenomegaly, long river rising in Ningxia and flowing into central Shaanxi 18.1cm, thick 6.3cm, form is full, smooth surface, essence echo is even.
Clinical diagnosis is: be diagnosed as hbv-liver cirrhosis, portal hypertension, splenomegaly spleen high, ascites forms, and takes medicine of the present invention, and decoction every day once also can be divided into and taking for twice, and sooner or later bfore meals is good.Through taking medicine of the present invention further consultation after 90 days, patient is without abdominal distention, and diet sleep is good.Have a medical check-up, abdominal part is flat soft, and without flatulence, both sides of the chest knocking is without pain sense, spirit still can, liver palm is good, body of the tongue is light red, have rosy cheeks, thready pulse.Ultrasound diagnosis result demonstration liver volume is still dwindled, and Echo heterogenicity is even, and it is smooth that liver shows to owe, portal vein diameter 12mm, the long river rising in Ningxia and flowing into central Shaanxi 15.1cm of Spleen Size, thick 4.3cm; Having no ascites forms.The demonstration of liver function result of laboratory test, paddy third, glutamic oxaloacetic transaminase, GOT are respectively 13.0 and 36.0; Total protein 67.0; Albumin is 33.0; Globulin 34.0; Bilirubin direct 9.2; Unconjugated bilirubin 13.2; Total bilirubin 22.4.Hepatitis B virus checks, hepatovirus surface antigen positive, the surface antibody positive, and core antibody positive, enjoins its maintenance dose as before of going back to take medicine, and maintenance dose is 1 time on the 1st, and instructions about how to take medicine are the same.Check afterwards on the 180th, ultrasound diagnosis result demonstration liver volume is still dwindled, and echo is evenly front, and it is smooth that liver shows to owe, portal vein diameter 11mm, Spleen Size major diameter 14.1cm, thick 4.2cm; Remaining normal.
Case 2:
Huang, female, 69 years old, examined in July, 2012, and appetite is poor, abdominal distention after meal, weak, both sides of the chest distending pain.Take Entecavir treatment.Clinical main physical signs: abdomen is flat soft, without tenderness, hepatic region is without button pain, and without liver palm, yellow urine, purplish tongue is dark, stringy pulse, chemical examination liver function is undesired, and paddy third, glutamic oxaloacetic transaminase, GOT are respectively 60 and 77.4; Total protein 57.0; Albumin is 30.0, globulin 27.0; Bilirubin direct 10.4, total bilirubin 22.6.Hepatitis B virus surface antigen is positive, remaining feminine gender, and Type B color doppler ultrasonic checks: liver volume form is roughly normal, rough, liver parenchyma echo unshapeliness, portal vein diameter 13mm, extrahepatic duct has no expansion.Splenomegaly, long 15.1cm, thick 4.3cm, form is full, smooth surface, essence echo is even.
Clinical diagnosis is: be diagnosed as hbv-liver cirrhosis, portal hypertension, splenomegaly, tell its all medicines of stopping using, with changing, take medicine of the present invention, decoction every day once also can be divided into and taking for twice, and sooner or later bfore meals is good.Through taking medicine of the present invention further consultation after 60 days, main stating, can have a meal, after meal abdominal distention not.Through looking into, abdominal part is without flatulence, and both sides of the chest knocking is without pain sense, spirit still can, body of the tongue is light red, have rosy cheeks, thready pulse.Ultrasound diagnosis result shows liver form normal in size, and Echo heterogenicity is even, and liver shows still to owe smooth, the long 13.1cm of Spleen Size, thick 3.3cm; Portal vein diameter 10mm, the demonstration of liver function result of laboratory test, paddy third, glutamic oxaloacetic transaminase, GOT are respectively 28.0 and 26.0; Total protein 70.0; Albumin is 33.0; Globulin 30.0; Bilirubin direct 3.2; Unconjugated bilirubin 14.2; Total bilirubin 19.5; Hepatitis B virus checks, the hepatitis B virus surface antigen positive, and remaining feminine gender, enjoins its maintenance dose as before of going back to take medicine, and maintenance dose is 1 time on the 1st, and instructions about how to take medicine are the same.After 90 days, check all normal.
Case 3
Wang, man, 39 years old, examined in March, 2012, took hepatagogue and Entecavir, checks that B-type hepatitis is that great three positive, splenomegaly are not light all the time, has a meal few, abdominal distention after meal, feels run-down, and becomes thin, both sides of the chest distending pain.
Clinical diagnosis is: right rib tenderness has lump, pain, and liver palm, yellow urine, purplish tongue is dark, stringy pulse, chemical examination liver function is undesired, and paddy third, glutamic oxaloacetic transaminase, GOT are respectively 189.0 and 176.7; Total protein 59.0; Albumin is 31.0, globulin 36.0; Bilirubin direct 15.5, total bilirubin 36.5.Hepatitis B virus positive, Type B color doppler ultrasonic checks: liver volume is dwindled, and form is roughly normal, rough, liver parenchyma echo unshapeliness, the portal vein diameter broadening rule of owing out of shape, extrahepatic duct has no expansion.Splenomegaly, thick 4.7cm, long river rising in Ningxia and flowing into central Shaanxi 13.1cm, form is full, smooth surface, essence echo is even, Dsv 0.8cm.
Clinical diagnosis is: hbv-liver cirrhosis, tell its all medicines of stopping using, and with changing, take medicine of the present invention, decoction every day once also can be divided into and taking for twice, and sooner or later bfore meals is good.Entecavir changes into and takes 2/3 every day, changes after taking 7 days again and takes half sheet, then change and take 1/3 after taking 7 days, withdraws Entecavir after taking 7 days.Through taking medicine of the present invention further consultation after 30 days, main stating, can have a meal, after meal not abdominal distention, urine is not yellow yet.Through looking into, abdominal part is without flatulence, and both sides of the chest knocking, without pain sense, is not laid one's hand on and lump under right rib, spirit still can, become thin alleviate, liver palm is good, body of the tongue is light red, have rosy cheeks, thready pulse.After 90 days, check that all are normal, the long 12.4cm of spleen, thick 3.9cm, follows up a case by regular visits to so far recurrence.
Hbv-liver cirrhosis diagnosis and treatment standard: by clinical symptoms be diet minimizing, abdominal distention after meal, feel sick, mental weariness, weak, become thin, both sides of the chest distending pain, right flank distending pain be hard, liver palm, yellow urine, purplish tongue is dark, stringy pulse, and chemical examination liver function is undesired, hepatitis B virus positive, liver, splenomegaly when Type B color doppler ultrasonic checks, liver tunicle thickens, and liver surface is rough, liver parenchyma Echoenhance, coarse unshapeliness, the broadening of portal vein diameter, ascites be diagnosed as hbv-liver cirrhosis.
Effective: above clinical symptoms all disappears;
Effective: above clinical symptoms partly disappears;
Invalid: not reach effective and effective evaluation criteria person.
200 hepatitis B patients of accumulative total are taken to the treatment effect of medicine of the present invention after 3 courses for the treatment of and add up, decoction every day once, 7th is a course for the treatment of.Statistical result is in Table 1
Therapeutic outcome see the following form (table 1, table 2):
Platelet curative effect example (%) after table 1. treatment
Above-mentioned clinical research shows: 200 routine hepatitis B patients of pharmaceutical composition clinical treatment of the present invention, treat effective 135 examples after 3 courses for the treatment of, and effective 24 examples, invalid 6 examples, total effective rate reaches 94.1%.Through treatment patient every clinical symptoms, also obviously improve, quality of life improves, the person that do not occur severity of symptoms, and the later stage is without recurrence.
Through clinical observation pharmaceutical composition of the present invention, have no toxic and side effects simultaneously.
Claims (4)
1. a medicine for the treatment of hbv-liver cirrhosis, it is characterized in that: described medicine is comprised of Fructus Evodiae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Hirudo (system), Tabanus (remove wing foot, fry), Radix Scutellariae, Ramulus Cinnamomi, Poria, Rhizoma Atractylodis Macrocephalae (parched), Semen Persicae, Semen Armeniacae Amarum (stir-fry), Radix Ginseng Rubra, Rhizoma Zingiberis, yellow Radix Aconiti Lateralis Preparata, Radix Glycyrrhizae Preparata.
2. the medicine of a kind of hbv-liver cirrhosis as claimed in claim 1, it is characterized in that, each component of described medicine is counted according to weight portion: Fructus Evodiae 40-80 part, Radix Angelicae Sinensis 100-130 part, Rhizoma Chuanxiong 100-130 part, Radix Rehmanniae 280-320 part, Radix Paeoniae Alba 100-130 part, Radix Et Rhizoma Rhei 280-320 part, Hirudo (system) 40-80 part, Tabanus (removes wing foot, fry) 40-80 part, Radix Scutellariae 40-80 part, Ramulus Cinnamomi 100-130 part, Poria 100-140 part, Rhizoma Atractylodis Macrocephalae (parched) 40-80 part, Semen Persicae 100-140 part, Semen Armeniacae Amarum (stir-fry) 100-130 part, Radix Ginseng Rubra 110-120 part, Rhizoma Zingiberis 100-130 part, yellow Radix Aconiti Lateralis Preparata 40-80 part, Radix Glycyrrhizae Preparata 80-100 part.
3. a kind of medicine for the treatment of hbv-liver cirrhosis as claimed in claim 1 or 2, it is characterized in that, each component of described medicine is counted according to weight portion: 60 parts of Fructus Evodiaes, 120 parts of Radix Angelicae Sinensis, 120 parts of Rhizoma Chuanxiong, 300 parts of Radix Rehmanniae, 120 parts of the Radix Paeoniae Albas, 300 parts of Radix Et Rhizoma Rhei, 60 parts of Hirudos (system), 60 parts of Tabanuss (remove wing foot, fry), 60 parts of Radix Scutellariaes, 120 parts of Ramulus Cinnamomi, 120 parts, Poria, 60 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 120 parts, Semen Persicae, 120 parts of Semen Armeniacae Amarums (stir-fry), 120 parts of Radix Ginseng Rubra, 120 parts of Rhizoma Zingiberiss, 60 parts of yellow Radix Aconiti Lateralis Preparatas, 90 parts of Radix Glycyrrhizae Preparata.
4. a kind of medicine for the treatment of hbv-liver cirrhosis as claimed in claim 1, its preparation method is: 1), according to described weight portion, claim medicine, clear water soaked after 2 hours, adds the decocting 2.5～3.5 hours of 13～17 times of weight, filters centrifugal removing slag, and is condensed into clear paste; 2), by step 1) gained clear paste adds conventional adjuvant, according to technique, is prepared into syrup, electuary, tablet, the watered pill, honeyed pill etc.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410468141.6A CN104174005A (en) | 2014-09-15 | 2014-09-15 | Medicine for treating hepatitis b cirrhosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410468141.6A CN104174005A (en) | 2014-09-15 | 2014-09-15 | Medicine for treating hepatitis b cirrhosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104174005A true CN104174005A (en) | 2014-12-03 |
Family
ID=51955533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410468141.6A Pending CN104174005A (en) | 2014-09-15 | 2014-09-15 | Medicine for treating hepatitis b cirrhosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104174005A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535892A (en) * | 2015-12-30 | 2016-05-04 | 北京资源亚太饲料科技有限公司 | Traditional Chinese medicine powder for preventing and treating accumulative toxicity and preparation method of traditional Chinese medicine powder |
| CN109172781A (en) * | 2018-11-22 | 2019-01-11 | 致宁医药（肇庆）股份有限公司 | A kind of Chinese medicine composition for treating hepatitis B, cirrhosis |
| CN111150826A (en) * | 2020-02-17 | 2020-05-15 | 河南中医药大学 | Traditional Chinese medicine for treating post-compensation hepatitis B cirrhosis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055285A (en) * | 2012-12-26 | 2013-04-24 | 柳州市中医院 | Traditional Chinese medicine for treating forepart hepetocirrhosis and preparation method thereof |
| CN103393986A (en) * | 2013-07-25 | 2013-11-20 | 田明军 | Traditional Chinese medicine composition for treating hepatitis b cirrhosis and preparation method thereof |
-
2014
- 2014-09-15 CN CN201410468141.6A patent/CN104174005A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055285A (en) * | 2012-12-26 | 2013-04-24 | 柳州市中医院 | Traditional Chinese medicine for treating forepart hepetocirrhosis and preparation method thereof |
| CN103393986A (en) * | 2013-07-25 | 2013-11-20 | 田明军 | Traditional Chinese medicine composition for treating hepatitis b cirrhosis and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 李希新等: "《当代内科难治病中医治疗》", 31 August 1997 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535892A (en) * | 2015-12-30 | 2016-05-04 | 北京资源亚太饲料科技有限公司 | Traditional Chinese medicine powder for preventing and treating accumulative toxicity and preparation method of traditional Chinese medicine powder |
| CN109172781A (en) * | 2018-11-22 | 2019-01-11 | 致宁医药（肇庆）股份有限公司 | A kind of Chinese medicine composition for treating hepatitis B, cirrhosis |
| CN111150826A (en) * | 2020-02-17 | 2020-05-15 | 河南中医药大学 | Traditional Chinese medicine for treating post-compensation hepatitis B cirrhosis |
| CN111150826B (en) * | 2020-02-17 | 2021-11-09 | 河南中医药大学 | Traditional Chinese medicine for treating post-compensation hepatitis B cirrhosis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103007191B (en) | Chinese medicinal composition for treating jaundice | |
| CN103908640A (en) | Traditional Chinese medicinal composition for treating liver cirrhosis | |
| CN103751570A (en) | Orally taken traditional Chinese medicine for treating migraine | |
| CN103861074A (en) | Traditional Chinese medicinal composition for treating menopausal arthritis | |
| CN105288371A (en) | Traditional Chinese medicine composition for curing gout | |
| CN103156934A (en) | Traditional Chinese medicine for treating apoplexy sequela | |
| CN100998722B (en) | Oral traditional Chinese medicine for treating delayed menstrual ciycle menalgia | |
| CN103638451A (en) | Traditional Chinese medicine for treating chronic hepatitis and preparation method thereof | |
| CN104174005A (en) | Medicine for treating hepatitis b cirrhosis | |
| CN103550728B (en) | A kind ofly treat the Chinese medicine composition that dampness-heat in the liver and gallbladder causes hypochondriac pain | |
| CN105535167A (en) | Chinese herb preparation of sport injury spray | |
| CN102526617A (en) | Chinese herbal medicine powder for lipid reduction and thrombolysis | |
| CN103520657B (en) | Traditional Chinese medicine composition for treating obese fatty liver | |
| CN102274445A (en) | Cassia twig common burreed rhizome tumor eliminating pills | |
| CN102283967B (en) | Chinese medicinal composition for treating pain in lateral lower abdomen | |
| CN101797369A (en) | Traditional Chinese medicinal composition for treating gastric atony | |
| CN103285343A (en) | Medicine for treating liver cancer and preparation method thereof | |
| CN104383517A (en) | Sugar with efficiency of relieving dysmenorrheal and preparation method thereof | |
| CN105561188A (en) | Decoction for treating ascites due to cirrhosis and preparation method thereof | |
| CN103285130B (en) | Chinese medicine composition for liver cancer treatment and preparing method thereof | |
| CN103007193B (en) | Chinese medicinal composition for treating gallbladder distention | |
| CN106214870A (en) | A kind of lavipeditum powder treating rheumatic arthritis and preparation method thereof | |
| CN105477557A (en) | Decoction drug for treating Qi-blood deficiency and blood stasis type diabetic foot and preparation method | |
| CN104667198A (en) | Traditional Chinese medicine composition for treating blood-heat toxic qi invasion type gout and application thereof | |
| CN104547959A (en) | Traditional Chinese medicine composition for treating hyperlipidemia and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20141203 |
|
| RJ01 | Rejection of invention patent application after publication |