CN105535784A - Traditional Chinese medicine composition for treating stomach illness and application thereof - Google Patents

Traditional Chinese medicine composition for treating stomach illness and application thereof Download PDF

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CN105535784A
CN105535784A CN201610007067.7A CN201610007067A CN105535784A CN 105535784 A CN105535784 A CN 105535784A CN 201610007067 A CN201610007067 A CN 201610007067A CN 105535784 A CN105535784 A CN 105535784A
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parts
chinese medicine
medicine composition
radix
crude drug
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唐玲
占希
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Dalian University
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Dalian University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/89—Cyperaceae (Sedge family)
    • A61K36/8905—Cyperus (flatsedge)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9064—Amomum, e.g. round cardamom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
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Abstract

The invention relates to a traditional Chinese medicine composition for treating stomach illness and application thereof, and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from, by weight, 10-35 parts of rhizoma polygonati, 5-15 parts of radix Ophiopogonis, 10-25 parts of wrinkled gianthyssop herb, 5-25 parts of radix paeoniae alba, 10-25 parts of the seed of Chinese dodder, 5-15 parts of fructus amomi, 10-35 parts of pseudo-ginseng, 5-15 parts of milkvetch roots, 5-15 parts of herba artemisiae scopariae, 10-25 parts of rhizoma cyperi, 5-15 parts of ternate buttercup roots and 5-15 parts of liquorice roots.

Description

A kind of Chinese medicine composition for the treatment of gastropathy and uses thereof
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of gastropathy, more particularly, relate to a kind ofly treat weakness of the spleen and stomach, the Chinese medicine composition of the disease such as cold syndrome of the stomach is had a pain, hyperchlorhydria and uses thereof.
Background technology
Gastric ulcer is digestive system common frdquently encountered disease, and sickness rate is in rising trend in recent years.Its pathophysiological process is comparatively complicated, summarizes and says to be attack factor to the destruction of gastric mucosa and defense factor to caused by the dysequilibrium of the protective effect of gastric mucosa.Attack factor has the upper small intestine liquid, helicobacter pylori etc. of gastric acid, pepsin, reflux; Protection factor comprises gastric mucosal barrier and gastric mucous barrier.Gastric mucosal barrier not only refers to the protective effect of gastric epithelial, and also includes gastric mucosal blood flow, the various gastric mucosal protection factor as prostaglandin etc.; Gastric mucous barrier and gastric mucus bicarbonate barrier.When any reason causes attack factor reinforcement or protective factors to weaken, all gastric mucosa injury can be caused.In addition, also find that oxygen-derived free radicals is combined lipid peroxide such as producing MDA with polyvalent unsaturated fatty acid in recent years, can failure line plastochondria and lysosome membrane, cause cell death, formation ulcer.Much Chinese medicine can effective scavenging activated oxygen, suppresses the lipid peroxidation in gastric mucosa, thus suppresses ulcer.
At present, conventional anti-ulcer medicament still fails to solve the high problem of ulcer recurrence rate clinically, and untoward reaction problem exposes increasingly.Market is urgent to novel anti-ulcer medicament demand that is efficient, low toxicity.In recent years, Chinese scholars has carried out the experimentation for the treatment of by Chinese herbs gastric ulcer, demonstrate Chinese medicine strengthening gastric mucosal defense ability, improve healing quality, reduce recurrence and toxicity low etc. in advantage, therefore the mechanism of action for the treatment of by Chinese herbs gastric ulcer and the discussion on working substance basis are more and more subject to people's attention.
Summary of the invention
In order to solve the above-mentioned problems in the prior art, the invention provides a kind of Chinese medicine preparation, described Chinese medicine preparation can treat weakness of the spleen and stomach, cold syndrome of the stomach is had a pain, the disease such as hyperchlorhydria, have that patient compliance is high, its effect is fast, good analgesic effect, the feature such as have no side effect.
According to an aspect of the present invention, a kind of Chinese medicine composition for the treatment of gastropathy is provided.
In one embodiment of the invention, described Chinese medicine composition is made up of the crude drug of following weight portion:
Rhizoma Polygonati 10-35 part 5-15 Radix Ophiopogonis part Herba Pogostemonis 10-25 part
Radix Paeoniae Alba 5-25 part Semen Cuscutae 10-25 part Fructus Amomi 5-15 part
Radix Notoginseng 10-35 part Radix Astragali 5-15 part Herba Artemisiae Scopariae 5-15 part
Rhizoma Cyperi 10-25 part Radix Ranunculi Ternati 5-15 part Radix Glycyrrhizae 5-15 part.
In the present invention's preferred embodiment, described Chinese medicine composition is made up of the crude drug of following weight portion:
Rhizoma Polygonati 15-25 part 10-15 Radix Ophiopogonis part Herba Pogostemonis 15-25 part
Radix Paeoniae Alba 10-20 part Semen Cuscutae 15-25 part Fructus Amomi 10-15 part
Radix Notoginseng 15-25 part Radix Astragali 10-15 part Herba Artemisiae Scopariae 10-15 part
Rhizoma Cyperi 15-20 part Radix Ranunculi Ternati 5-10 part Radix Glycyrrhizae 5-10 part.
In another preferred embodiment of the present invention, described Chinese medicine composition is made up of the crude drug of following weight portion:
Rhizoma Polygonati 15 portions of Herba Pogostemoniss, 20 parts of Radix Ophiopogonis 15 parts
The Radix Paeoniae Alba 15 parts of Semen Cuscutae 20 parts of Fructus Amomis 10 parts
Radix Notoginseng 15 parts of Radixs Astragali 15 parts of Herba Artemisiae Scopariae 10 parts
5 parts, Rhizoma Cyperi 15 portions of Radix Ranunculi Ternatis 10 portions of Radix Glycyrrhizaes.
According to a further aspect in the invention, provide a kind of method preparing above-mentioned Chinese medicine composition, comprise the steps:
(1) crude drug taking described weight proportion is for subsequent use;
(2) above 12 taste medicine mixed powders are broken into fine powder, cross 80 mesh sieves; Mix homogeneously, respectively with 8,8,10 times amount water extraction three times, each 1.5 hours, filter merging filtrate, add ethanol to 85%, hold over night, filter and abandon precipitation, filtrate reduced in volume obtains concentrated solution, vacuum drying, obtains Chinese medicine composition.
In accordance with a further aspect of the present invention, the purposes of above-mentioned Chinese medicine composition in the medicine of preparation treatment gastropathy is provided.
Detailed description of the invention
Exploitativeness of the present invention is further described below by embodiment; for a person skilled in the art; should be understood to, the following examples are not limiting the scope of the invention, still belong to protection scope of the present invention to the equivalent replacement of some technical characteristic.
Embodiment 1
Prescription: Rhizoma Polygonati 20g 15g Radix Ophiopogonis Herba Pogostemonis 15g Radix Paeoniae Alba 15g Semen Cuscutae 20g Fructus Amomi 10g Radix Notoginseng 15g Radix Astragali 15g Herba Artemisiae Scopariae 10g Rhizoma Cyperi 15g Radix Ranunculi Ternati 10g Radix Glycyrrhizae 5g.
Method for making: the crude drug taking described weight proportion is for subsequent use; Above 12 taste medicine mixed powders are broken into fine powder, cross 80 mesh sieves; Mix homogeneously, respectively with 8,8,10 times amount water extraction three times, each 1.5 hours, filter merging filtrate, add ethanol to 85%, hold over night, filter and abandon precipitation, filtrate reduced in volume obtains concentrated solution, vacuum drying, obtains Chinese medicine composition (yield 8.9%).
Embodiment 2 Chinese medicine composition is on the impact of chmice acute gastric ulcer model
Get male ICR mouse, about body weight 25g, random packet (n=10), matched group (0.2%CMCNa, 10ml/kg, i.g.), positive controls (cimetidine, 50mg/kg, i.g.), Chinese medicine composition group (prepared by 25,50mg/kg, i.g. embodiment 1).After administration 50 minutes, gavage is given and 0.2ml, 0.3MHCl/60%EtOH causes ulcer, get stomach after 1 hour, inject 1ml normal saline and make it expand, after the formalin with 5% fixes 30 minutes, cut off along greater gastric curvature, on macroscopic gastric mucosa parallel stomach long axis direction have elongation black-red tape, measure the length (mm) of each ulcer, ulcer index (UI) is all ulcer length sums.
Suppression ratio calculates:
Suppression ratio=[UI (matched group)-UI (administration group)]/UI (matched group) × 100%
Concrete outcome is as follows:
Wherein, the Chinese medicine composition preparation method of comparative example 1 is with embodiment 1, and difference is only to remove Rhizoma Cyperi in medical material.
The Chinese medicine composition preparation method of comparative example 2 is with embodiment 1, and difference is only to remove the Radix Astragali in medical material.
Embodiment 3 Chinese medicine composition is on the impact of rat chronic gastritis model
Get SD rat, male and female half and half, about body weight 150g, random packet, often organize 15.For blank group (certainly drinking tap water); Model group (ammonia from drink 0.1% newly configuration); Administration group (ammonia from drink 0.1% newly configuration), after continuous modeling 180d, terminates modeling.The normal saline of blank group and model group gavage same volume; Chinese medicine composition 25mg/kg prepared by administration group difference gastric infusion embodiment 1, successive administration 90d, every day 1 time, after last administration, often group gets 5 rats, measures Gastric Mucosa Blood Flow amount (GMBF) with neutral red clearance.All the other Rat Fast 16h, anesthesia opens abdomen, ligation pylorus, to gastric saline injection 3ml, wins full stomach after 15min, collects rat gastric juice in graduated centrifuge tube.Mus stomach carries out routine and dissects, clean gastric content, and with distilled water flushing 2 times, use filter paper suck dry moisture, the full gastric mucosa of careful scraping 1/3 is weighed, add the homogenate of appropriate distilled water Soniprep, make gastric mucosa homogenate, measure gastric mucosa superoxide dismutase (SOD) vigor, malonaldehyde (MDA) content.Gastric juice, after centrifugal, measures total acidity gastric juice and pepsin activity.
Concrete outcome is as follows:
1, Chinese medicine composition is on the impact of Gastric Mucosa Blood Flow amount
2, Chinese medicine composition is on the impact of SOD and MDA
3, Chinese medicine composition is on the impact of total acidity gastric juice and pepsin activity
Embodiment 4 clinical trial
The routine patient of clinical observation 94, is diagnosed as active stage ulcer through gastroscopy, and Syndrome Differentiation of Traditional Chinese Medicine is asthenic cold type gastric abscess.Each oral meal embodiment 1 Chinese medicinal composition granules (Chinese medicine composition dosage is about 20mg/kg), every day three times, medicine time is 3 weeks, after 3 weeks, carry out traditional Chinese medical science four diagnostic methods dialectical Analyses and fibergastroscopy.
In all cases before the treatment, all there is the symptom such as nausea and vomiting, acid regurgitation, abdominal distention in various degree in patient, and after taking above-mentioned Chinese medicine composition, above-mentioned symptom disappearance 76 is routine, and take a turn for the better 15 examples, and total effective rate is 96%.Gastroscopy result shows, clinical cure 69 example in promotion ulcer healing, and effective 21 examples, total effective rate is 92%.
Content of the present invention merely illustrates some claimed specific embodiments; one of them or more described technical characteristic can be combined with arbitrary one or more technical scheme in technical scheme; these technical schemes obtained through combination also in the application's protection domain, just as these technical schemes obtained through combination in the disclosure of invention concrete record.

Claims (6)

1. treat a Chinese medicine composition for gastropathy, it is characterized in that, this Chinese medicine composition is made up of the crude drug of following weight portion:
Rhizoma Polygonati 10-35 part 5-15 Radix Ophiopogonis part Herba Pogostemonis 10-25 part
Radix Paeoniae Alba 5-25 part Semen Cuscutae 10-25 part Fructus Amomi 5-15 part
Radix Notoginseng 10-35 part Radix Astragali 5-15 part Herba Artemisiae Scopariae 5-15 part
Rhizoma Cyperi 10-25 part Radix Ranunculi Ternati 5-15 part Radix Glycyrrhizae 5-15 part.
2. Chinese medicine composition according to claim 1, is characterized in that, this Chinese medicine composition is made up of the crude drug of following weight portion:
Rhizoma Polygonati 15-25 part 10-15 Radix Ophiopogonis part Herba Pogostemonis 15-25 part
Radix Paeoniae Alba 10-20 part Semen Cuscutae 15-25 part Fructus Amomi 10-15 part
Radix Notoginseng 15-25 part Radix Astragali 10-15 part Herba Artemisiae Scopariae 10-15 part
Rhizoma Cyperi 15-20 part Radix Ranunculi Ternati 5-10 part Radix Glycyrrhizae 5-10 part.
3. Chinese medicine composition according to claim 2, is characterized in that, this Chinese medicine composition is made up of the crude drug of following weight portion:
Rhizoma Polygonati 15 portions of Herba Pogostemoniss, 20 parts of Radix Ophiopogonis 15 parts
The Radix Paeoniae Alba 15 parts of Semen Cuscutae 20 parts of Fructus Amomis 10 parts
Radix Notoginseng 15 parts of Radixs Astragali 15 parts of Herba Artemisiae Scopariae 10 parts
5 parts, Rhizoma Cyperi 15 portions of Radix Ranunculi Ternatis 10 portions of Radix Glycyrrhizaes.
4. the Chinese medicine composition according to claims 1 to 3, is characterized in that, described Chinese medicine composition is made the dosage forms such as tablet, pill, granule or capsule.
5. the preparation method of Chinese medicine composition as claimed in claim 1, is characterized in that, comprise the steps:
(1) crude drug taking described weight proportion is for subsequent use;
(2) above 12 taste medicine mixed powders are broken into fine powder, cross 80 mesh sieves; Mix homogeneously, respectively with 8,8,10 times amount water extraction three times, each 1.5 hours, filter merging filtrate, add ethanol to 85%, hold over night, filter and abandon precipitation, filtrate reduced in volume obtains concentrated solution, vacuum drying, obtains Chinese medicine composition.
6. the purposes of the Chinese medicine composition of claim 1-3 in the medicine of preparation treatment gastropathy.
CN201610007067.7A 2016-01-07 2016-01-07 Traditional Chinese medicine composition for treating stomach illness and application thereof Pending CN105535784A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105878906A (en) * 2016-07-01 2016-08-24 北京怡成堂中医药研究院 Traditional Chinese medicine composition and preparation method thereof
CN115554374A (en) * 2022-10-13 2023-01-03 河北中医学院 Traditional Chinese medicine composition for treating helicobacter pylori gastritis and preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101066286A (en) * 2007-06-07 2007-11-07 沈阳药科大学 Coastal glehnia root extract with function of antagonizing gastric ulcer and its prepn
CN101396542A (en) * 2008-11-13 2009-04-01 陕西东泰制药有限公司 Traditional Chinese medicine formulation for treating gastrosis and preparation method thereof
CN103800786A (en) * 2014-02-28 2014-05-21 娄渊贵 Traditional Chinese medicinal compound preparation for treating gastric diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101066286A (en) * 2007-06-07 2007-11-07 沈阳药科大学 Coastal glehnia root extract with function of antagonizing gastric ulcer and its prepn
CN101396542A (en) * 2008-11-13 2009-04-01 陕西东泰制药有限公司 Traditional Chinese medicine formulation for treating gastrosis and preparation method thereof
CN103800786A (en) * 2014-02-28 2014-05-21 娄渊贵 Traditional Chinese medicinal compound preparation for treating gastric diseases

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Title
张立富: "养胃消萎汤治疗萎缩性胃炎32例", 《四川中医》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105878906A (en) * 2016-07-01 2016-08-24 北京怡成堂中医药研究院 Traditional Chinese medicine composition and preparation method thereof
CN115554374A (en) * 2022-10-13 2023-01-03 河北中医学院 Traditional Chinese medicine composition for treating helicobacter pylori gastritis and preparation method and application thereof
CN115554374B (en) * 2022-10-13 2023-07-07 河北中医学院 Traditional Chinese medicine composition for treating helicobacter pylori gastritis as well as preparation method and application thereof

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