CN105534866A - Preparation method of multiple-effect toothpaste capable of removing stains and conducting maintenance - Google Patents
Preparation method of multiple-effect toothpaste capable of removing stains and conducting maintenance Download PDFInfo
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- CN105534866A CN105534866A CN201610048906.XA CN201610048906A CN105534866A CN 105534866 A CN105534866 A CN 105534866A CN 201610048906 A CN201610048906 A CN 201610048906A CN 105534866 A CN105534866 A CN 105534866A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/982—Reproductive organs; Embryos, Eggs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/985—Skin or skin outgrowth, e.g. hair, nails
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Abstract
The invention discloses a preparation method of multiple-effect toothpaste capable of removing stains and conducting maintenance. The toothpaste comprises 3-8 parts of sorbitol, 5-10 parts of glycerin, 2-7 parts of xanthan gum, 1-3 parts of bis-oxy phenyl bi-guanidyl hexane, 2-7 parts of starch, 3-9 parts of sodium carboxymethylcellulose, 2-9 parts of tetrasodium pyrophosphate and 0.01-0.1 part of sodium monofluorophosphate. The preparation method comprises the steps of placing the starch into a premixing pot, conducting stirring while adding the sodium carboxymethylcellulose, so that sodium carboxymethylcellulose, the tetrasodium pyrophosphate and the sodium monofluorophosphate are uniformly dispersed in a mixture of the glycerin, the xanthan gum, the bis-oxy phenyl bi-guanidyl hexane and the sorbitol, and suspending liquid A is obtained. The preparation method is simple in preparation process and convenient to operate, and the obtained toothpaste has good tooth stain removal efficacy, can conduct sterilization and disinfection on the oral cavity, keep teeth in the oral cavity clean, maintain gingiva and prevent redness and swelling of the gingiva and can further promote regeneration of the gingiva.
Description
[technical field]
The present invention relates to the technical field of toothpaste, particularly the technical field of efficient stains removing toothpaste preparation method.
[background technology]
Toothpaste is cleaning supplies conventional in daily life, has very long history.Along with the development of science and technology, technological equipment update and perfect, various types of toothpaste is come out one after another, and quality and the class of product improve constantly, and it is single that the toothpaste on existing market exists effect, the problem that tooth stain of dispelling effect is undesirable.
[summary of the invention]
Object of the present invention solves the problems of the prior art exactly, a kind of preparation method of stains removing maintenance multiple-effect toothpaste is proposed, preparation technology is simple, easy to operate, obtained toothpaste has good tooth stain effect of dispelling, and can carry out sterilizing to oral cavity, keep Buccodental clean, maintenance gingiva, prevents red swelling of gingiva, can also promote that gingiva regenerates.
For achieving the above object, the present invention proposes a kind of preparation method of stains removing maintenance multiple-effect toothpaste, comprise the following steps successively:
A) by sorbitol: 3 ~ 8 parts, glycerol: 5 ~ 10 parts, xanthan gum: 2 ~ 7 parts, dioxygen is for phenyl two guanidine radicals hexane: 1 ~ 3 part, starch: put into premix pot, add sodium carboxymethyl cellulose while stirring for 2 ~ 7 parts: 3 ~ 9 parts, tetrasodium pyrophosphate: 2 ~ 9 parts, sodium monofluorophosphate: 0.01 ~ 0.1 part, makes carboxymethyl cellulose, plain sodium tetrasodium pyrophosphate and sodium monofluorophosphate be dispersed in glycerol, xanthan gum, dioxygen in phenyl two guanidine radicals hexane and sorbitol, obtained suspending liquid A;
B) by stains removing agent: 3 ~ 8 parts, enzyme preparation: 2 ~ 6 parts, sodium fluoride: 0.1 ~ 1 part, green tea extract: 2 ~ 6 parts, stevioside: 1 ~ 7 part, Oleum menthae: 2 ~ 5 parts, water: 12 ~ 25 parts, strontium chloride: 1 ~ 3 part, paeonol: 1 ~ 4 part, thymol: 2 ~ 5 parts, Herba Asari: 4 ~ 9 parts, Herba Schizonepetae: 2 ~ 6 parts, immunoglobulin: 1 ~ 4 part, Radix Berberidis extract: 3 ~ 8 parts, Semen Arecae extract: 2 ~ 6 parts, Herba Patriniae: 1 ~ 6 part, Rhizoma Belamcandae: 2 ~ 7 parts, Oleum Bulbus Allii: 1 ~ 7 part, Cornu Cervi pectin: 2 ~ 7 parts, copper chlorophyllin sodium salt: 1 ~ 4 part, stannous fluoride: 0.1 ~ 1 part, raw Bulbus Allii Cepae extract: 3 ~ 8 parts, mustard: 2 ~ 6 parts, Halitum: 4 ~ 10 parts, Rumalus sophorae extract: 3 ~ 7 parts, Radix Ophiopogonis: 2 ~ 5 parts, fresh Turnip extractive: 2 ~ 8 parts, Oleum Caryophylli: 1 ~ 3 part, 'pearl powder ': 2 ~ 5 parts, Radix et Caulis Opuntiae Dillenii extract: 3 ~ 9 parts, Fructus Piperis Longi: 2 ~ 6 parts, Lasiosphaera Seu Calvatia: 4 ~ 9 parts, Fructus Arctii: 1 ~ 6 part, Nidus Vespae: 2 ~ 5 parts, Mel: 1 ~ 5 part of obtained mixed liquid B of mixing,
C) add in premix pot by suspension B, suspending liquid A and mixed liquid B are uniformly mixed, mixing time is 4h, and during stirring, control temperature is at 25 DEG C, obtains colloid C;
D) by still aging for the colloid in step c 5h, the viscosity of colloid is controlled at 250 ~ 400Pa.s, colloid and 3 ~ 8 parts of calcium bisulfates, 5 ~ 15 parts of anhydride silicas, 2 ~ 10 parts of hydroxyapatite are together added in grinder and carries out grinding 5h;
E), in the colloid vacuum outgas pot after steps d being ground, deviate from the bubble produced because of grinding by the vacuum outgas of-0.2 ~-0.1MPa, degassing time is 3h.
As preferably, described stains removing agent adopts the one or any several mixture in carbamide, zinc citrate and Quadrafos.
As preferably, described enzyme preparation adopts the one or any several mixture in dextranase, amylase, protease and lysozyme.
As preferably, the viscosity of described sodium carboxymethyl cellulose is 1100 ~ 1200mPa.s, and the degree of etherification falling of sodium carboxymethyl cellulose is greater than 0.9.
As preferably, described immunoglobulin extracts the yolk from hen.
Beneficial effect of the present invention: preparation technology of the present invention is simple, easy to operate, obtained toothpaste has good tooth stain function of dispelling, gingiva blood circulation can be promoted simultaneously, the multiple oral problem such as prophylaxis of teeth allergy and gingival hemorrhage, the anti-microbial property of dental surface can be strengthened by adding immunoglobulin in toothpaste, effectively can suppress activity and the absorption of Streptococcus mutans, sterilizing can be carried out to oral cavity, keep Buccodental clean, maintenance gingiva, can effectively eliminate and prevent red swelling of gingiva, and eliminate the problem of gingival hemorrhage, can also promote that gingiva regenerates.Sulphur compound in Bulbus Allii Cepae is strong antimicrobial component, and Bulbus Allii Cepae can kill various bacteria, the Streptococcus mutans decayed tooth comprising causing us, and best with fresh raw Bulbus Allii Cepae effect.
[detailed description of the invention]
Embodiment one:
A preparation method for stains removing maintenance multiple-effect toothpaste, comprises the following steps successively:
A) by sorbitol: 3 ~ 8 parts, glycerol: 5 ~ 10 parts, xanthan gum: 2 ~ 7 parts, dioxygen is for phenyl two guanidine radicals hexane: 1 ~ 3 part, starch: put into premix pot, add sodium carboxymethyl cellulose while stirring for 2 ~ 7 parts: 3 ~ 9 parts, tetrasodium pyrophosphate: 2 ~ 9 parts, sodium monofluorophosphate: 0.01 ~ 0.1 part, makes carboxymethyl cellulose, plain sodium tetrasodium pyrophosphate and sodium monofluorophosphate be dispersed in glycerol, xanthan gum, dioxygen in phenyl two guanidine radicals hexane and sorbitol, obtained suspending liquid A;
B) by stains removing agent: 3 ~ 8 parts, enzyme preparation: 2 ~ 6 parts, sodium fluoride: 0.1 ~ 1 part, green tea extract: 2 ~ 6 parts, stevioside: 1 ~ 7 part, Oleum menthae: 2 ~ 5 parts, water: 12 ~ 25 parts, strontium chloride: 1 ~ 3 part, paeonol: 1 ~ 4 part, thymol: 2 ~ 5 parts, Herba Asari: 4 ~ 9 parts, Herba Schizonepetae: 2 ~ 6 parts, immunoglobulin: 1 ~ 4 part, Radix Berberidis extract: 3 ~ 8 parts, Semen Arecae extract: 2 ~ 6 parts, Herba Patriniae: 1 ~ 6 part, Rhizoma Belamcandae: 2 ~ 7 parts, Oleum Bulbus Allii: 1 ~ 7 part, Cornu Cervi pectin: 2 ~ 7 parts, copper chlorophyllin sodium salt: 1 ~ 4 part, stannous fluoride: 0.1 ~ 1 part, raw Bulbus Allii Cepae extract: 3 ~ 8 parts, mustard: 2 ~ 6 parts, Halitum: 4 ~ 10 parts, Rumalus sophorae extract: 3 ~ 7 parts, Radix Ophiopogonis: 2 ~ 5 parts, fresh Turnip extractive: 2 ~ 8 parts, Oleum Caryophylli: 1 ~ 3 part, 'pearl powder ': 2 ~ 5 parts, Radix et Caulis Opuntiae Dillenii extract: 3 ~ 9 parts, Fructus Piperis Longi: 2 ~ 6 parts, Lasiosphaera Seu Calvatia: 4 ~ 9 parts, Fructus Arctii: 1 ~ 6 part, Nidus Vespae: 2 ~ 5 parts, Mel: 1 ~ 5 part of obtained mixed liquid B of mixing,
C) add in premix pot by suspension B, suspending liquid A and mixed liquid B are uniformly mixed, mixing time is 4h, and during stirring, control temperature is at 25 DEG C, obtains colloid C;
D) by still aging for the colloid in step c 5h, the viscosity of colloid is controlled at 250 ~ 400Pa.s, colloid and 3 ~ 8 parts of calcium bisulfates, 5 ~ 15 parts of anhydride silicas, 2 ~ 10 parts of hydroxyapatite are together added in grinder and carries out grinding 5h;
E), in the colloid vacuum outgas pot after steps d being ground, deviate from the bubble produced because of grinding by the vacuum outgas of-0.2 ~-0.1MPa, degassing time is 3h.
Stains removing agent adopts carbamide, and enzyme preparation adopts dextranase, and the viscosity of sodium carboxymethyl cellulose is 1100Pa.s, and the degree of etherification falling of sodium carboxymethyl cellulose is greater than 0.9, and described immunoglobulin extracts the yolk from hen.
Embodiment two:
A preparation method for stains removing maintenance multiple-effect toothpaste, comprises the following steps successively:
A) by sorbitol: 3 ~ 8 parts, glycerol: 5 ~ 10 parts, xanthan gum: 2 ~ 7 parts, dioxygen is for phenyl two guanidine radicals hexane: 1 ~ 3 part, starch: put into premix pot, add sodium carboxymethyl cellulose while stirring for 2 ~ 7 parts: 3 ~ 9 parts, tetrasodium pyrophosphate: 2 ~ 9 parts, sodium monofluorophosphate: 0.01 ~ 0.1 part, makes carboxymethyl cellulose, plain sodium tetrasodium pyrophosphate and sodium monofluorophosphate be dispersed in glycerol, xanthan gum, dioxygen in phenyl two guanidine radicals hexane and sorbitol, obtained suspending liquid A;
B) by stains removing agent: 3 ~ 8 parts, enzyme preparation: 2 ~ 6 parts, sodium fluoride: 0.1 ~ 1 part, green tea extract: 2 ~ 6 parts, stevioside: 1 ~ 7 part, Oleum menthae: 2 ~ 5 parts, water: 12 ~ 25 parts, strontium chloride: 1 ~ 3 part, paeonol: 1 ~ 4 part, thymol: 2 ~ 5 parts, Herba Asari: 4 ~ 9 parts, Herba Schizonepetae: 2 ~ 6 parts, immunoglobulin: 1 ~ 4 part, Radix Berberidis extract: 3 ~ 8 parts, Semen Arecae extract: 2 ~ 6 parts, Herba Patriniae: 1 ~ 6 part, Rhizoma Belamcandae: 2 ~ 7 parts, Oleum Bulbus Allii: 1 ~ 7 part, Cornu Cervi pectin: 2 ~ 7 parts, copper chlorophyllin sodium salt: 1 ~ 4 part, stannous fluoride: 0.1 ~ 1 part, raw Bulbus Allii Cepae extract: 3 ~ 8 parts, mustard: 2 ~ 6 parts, Halitum: 4 ~ 10 parts, Rumalus sophorae extract: 3 ~ 7 parts, Radix Ophiopogonis: 2 ~ 5 parts, fresh Turnip extractive: 2 ~ 8 parts, Oleum Caryophylli: 1 ~ 3 part, 'pearl powder ': 2 ~ 5 parts, Radix et Caulis Opuntiae Dillenii extract: 3 ~ 9 parts, Fructus Piperis Longi: 2 ~ 6 parts, Lasiosphaera Seu Calvatia: 4 ~ 9 parts, Fructus Arctii: 1 ~ 6 part, Nidus Vespae: 2 ~ 5 parts, Mel: 1 ~ 5 part of obtained mixed liquid B of mixing,
C) add in premix pot by suspension B, suspending liquid A and mixed liquid B are uniformly mixed, mixing time is 4h, and during stirring, control temperature is at 25 DEG C, obtains colloid C;
D) by still aging for the colloid in step c 5h, the viscosity of colloid is controlled at 250 ~ 400Pa.s, colloid and 3 ~ 8 parts of calcium bisulfates, 5 ~ 15 parts of anhydride silicas, 2 ~ 10 parts of hydroxyapatite are together added in grinder and carries out grinding 5h;
E), in the colloid vacuum outgas pot after steps d being ground, deviate from the bubble produced because of grinding by the vacuum outgas of-0.2 ~-0.1MPa, degassing time is 3h.
Stains removing agent adopts the mixture of carbamide, zinc citrate, enzyme preparation adopts the mixture of dextranase, amylase, protease and lysozyme, the viscosity of sodium carboxymethyl cellulose is 1150mPa.s, and the degree of etherification falling of sodium carboxymethyl cellulose is greater than 0.9, and immunoglobulin extracts the yolk from hen.
Embodiment three:
A preparation method for stains removing maintenance multiple-effect toothpaste, comprises the following steps successively:
A) by sorbitol: 3 ~ 8 parts, glycerol: 5 ~ 10 parts, xanthan gum: 2 ~ 7 parts, dioxygen is for phenyl two guanidine radicals hexane: 1 ~ 3 part, starch: put into premix pot, add sodium carboxymethyl cellulose while stirring for 2 ~ 7 parts: 3 ~ 9 parts, tetrasodium pyrophosphate: 2 ~ 9 parts, sodium monofluorophosphate: 0.01 ~ 0.1 part, makes carboxymethyl cellulose, plain sodium tetrasodium pyrophosphate and sodium monofluorophosphate be dispersed in glycerol, xanthan gum, dioxygen in phenyl two guanidine radicals hexane and sorbitol, obtained suspending liquid A;
B) by stains removing agent: 3 ~ 8 parts, enzyme preparation: 2 ~ 6 parts, sodium fluoride: 0.1 ~ 1 part, green tea extract: 2 ~ 6 parts, stevioside: 1 ~ 7 part, Oleum menthae: 2 ~ 5 parts, water: 12 ~ 25 parts, strontium chloride: 1 ~ 3 part, paeonol: 1 ~ 4 part, thymol: 2 ~ 5 parts, Herba Asari: 4 ~ 9 parts, Herba Schizonepetae: 2 ~ 6 parts, immunoglobulin: 1 ~ 4 part, Radix Berberidis extract: 3 ~ 8 parts, Semen Arecae extract: 2 ~ 6 parts, Herba Patriniae: 1 ~ 6 part, Rhizoma Belamcandae: 2 ~ 7 parts, Oleum Bulbus Allii: 1 ~ 7 part, Cornu Cervi pectin: 2 ~ 7 parts, copper chlorophyllin sodium salt: 1 ~ 4 part, stannous fluoride: 0.1 ~ 1 part, raw Bulbus Allii Cepae extract: 3 ~ 8 parts, mustard: 2 ~ 6 parts, Halitum: 4 ~ 10 parts, Rumalus sophorae extract: 3 ~ 7 parts, Radix Ophiopogonis: 2 ~ 5 parts, fresh Turnip extractive: 2 ~ 8 parts, Oleum Caryophylli: 1 ~ 3 part, 'pearl powder ': 2 ~ 5 parts, Radix et Caulis Opuntiae Dillenii extract: 3 ~ 9 parts, Fructus Piperis Longi: 2 ~ 6 parts, Lasiosphaera Seu Calvatia: 4 ~ 9 parts, Fructus Arctii: 1 ~ 6 part, Nidus Vespae: 2 ~ 5 parts, Mel: 1 ~ 5 part of obtained mixed liquid B of mixing,
C) add in premix pot by suspension B, suspending liquid A and mixed liquid B are uniformly mixed, mixing time is 4h, and during stirring, control temperature is at 25 DEG C, obtains colloid C;
D) by still aging for the colloid in step c 5h, the viscosity of colloid is controlled at 250 ~ 400Pa.s, colloid and 3 ~ 8 parts of calcium bisulfates, 5 ~ 15 parts of anhydride silicas, 2 ~ 10 parts of hydroxyapatite are together added in grinder and carries out grinding 5h;
E), in the colloid vacuum outgas pot after steps d being ground, deviate from the bubble produced because of grinding by the vacuum outgas of-0.2 ~-0.1MPa, degassing time is 3h.
Stains removing agent adopts the mixture of carbamide, zinc citrate and Quadrafos, enzyme preparation adopts the mixture of dextranase, protease and lysozyme, the viscosity of sodium carboxymethyl cellulose is 1200mPa.s, and the degree of etherification falling of sodium carboxymethyl cellulose is greater than 0.9, and immunoglobulin extracts the yolk from hen.
Above-described embodiment is to explanation of the present invention, is not limitation of the invention, anyly all belongs to protection scope of the present invention to the scheme after simple transformation of the present invention.
Claims (5)
1. a preparation method for stains removing maintenance multiple-effect toothpaste, comprises the following steps successively:
A) by sorbitol: 3 ~ 8 parts, glycerol: 5 ~ 10 parts, xanthan gum: 2 ~ 7 parts, dioxygen is for phenyl two guanidine radicals hexane: 1 ~ 3 part, starch: put into premix pot, add sodium carboxymethyl cellulose while stirring for 2 ~ 7 parts: 3 ~ 9 parts, tetrasodium pyrophosphate: 2 ~ 9 parts, sodium monofluorophosphate: 0.01 ~ 0.1 part, makes carboxymethyl cellulose, plain sodium tetrasodium pyrophosphate and sodium monofluorophosphate be dispersed in glycerol, xanthan gum, dioxygen in phenyl two guanidine radicals hexane and sorbitol, obtained suspending liquid A;
B) by stains removing agent: 3 ~ 8 parts, enzyme preparation: 2 ~ 6 parts, sodium fluoride: 0.1 ~ 1 part, green tea extract: 2 ~ 6 parts, stevioside: 1 ~ 7 part, Oleum menthae: 2 ~ 5 parts, water: 12 ~ 25 parts, strontium chloride: 1 ~ 3 part, paeonol: 1 ~ 4 part, thymol: 2 ~ 5 parts, Herba Asari: 4 ~ 9 parts, Herba Schizonepetae: 2 ~ 6 parts, immunoglobulin: 1 ~ 4 part, Radix Berberidis extract: 3 ~ 8 parts, Semen Arecae extract: 2 ~ 6 parts, Herba Patriniae: 1 ~ 6 part, Rhizoma Belamcandae: 2 ~ 7 parts, Oleum Bulbus Allii: 1 ~ 7 part, Cornu Cervi pectin: 2 ~ 7 parts, copper chlorophyllin sodium salt: 1 ~ 4 part, stannous fluoride: 0.1 ~ 1 part, raw Bulbus Allii Cepae extract: 3 ~ 8 parts, mustard: 2 ~ 6 parts, Halitum: 4 ~ 10 parts, Rumalus sophorae extract: 3 ~ 7 parts, Radix Ophiopogonis: 2 ~ 5 parts, fresh Turnip extractive: 2 ~ 8 parts, Oleum Caryophylli: 1 ~ 3 part, 'pearl powder ': 2 ~ 5 parts, Radix et Caulis Opuntiae Dillenii extract: 3 ~ 9 parts, Fructus Piperis Longi: 2 ~ 6 parts, Lasiosphaera Seu Calvatia: 4 ~ 9 parts, Fructus Arctii: 1 ~ 6 part, Nidus Vespae: 2 ~ 5 parts, Mel: 1 ~ 5 part of obtained mixed liquid B of mixing,
C) add in premix pot by suspension B, suspending liquid A and mixed liquid B are uniformly mixed, mixing time is 4h, and during stirring, control temperature is at 25 DEG C, obtains colloid C;
D) by still aging for the colloid in step c 5h, the viscosity of colloid is controlled at 250 ~ 400Pa.s, colloid and 3 ~ 8 parts of calcium bisulfates, 5 ~ 15 parts of anhydride silicas, 2 ~ 10 parts of hydroxyapatite are together added in grinder and carries out grinding 5h;
E), in the colloid vacuum outgas pot after steps d being ground, deviate from the bubble produced because of grinding by the vacuum outgas of-0.2 ~-0.1MPa, degassing time is 3h.
2. the preparation method of a kind of stains removing maintenance multiple-effect toothpaste as claimed in claim 1, is characterized in that: described stains removing agent adopts the one or any several mixture in carbamide, zinc citrate and Quadrafos.
3. the preparation method of a kind of stains removing maintenance multiple-effect toothpaste as claimed in claim 1, is characterized in that: described enzyme preparation adopts the one or any several mixture in dextranase, amylase, protease and lysozyme.
4. the preparation method of a kind of stains removing maintenance multiple-effect toothpaste as claimed in claim 1, is characterized in that: the viscosity of described sodium carboxymethyl cellulose is 1100 ~ 1200mPa.s, and the degree of etherification falling of sodium carboxymethyl cellulose is greater than 0.9.
5. the preparation method of a kind of stains removing maintenance multiple-effect toothpaste as claimed in claim 1, is characterized in that: described immunoglobulin extracts the yolk from hen.
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| CN116392410A (en) * | 2023-03-23 | 2023-07-07 | 段梅莉 | Functional toothpaste and preparation method thereof |
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