CN105510613A - Reagent blending conveying device and blending method - Google Patents
Reagent blending conveying device and blending method Download PDFInfo
- Publication number
- CN105510613A CN105510613A CN201510961493.XA CN201510961493A CN105510613A CN 105510613 A CN105510613 A CN 105510613A CN 201510961493 A CN201510961493 A CN 201510961493A CN 105510613 A CN105510613 A CN 105510613A
- Authority
- CN
- China
- Prior art keywords
- conveyer
- reagent
- mixing
- kit
- mixing mechanism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/30—Mixing the contents of individual packages or containers, e.g. by rotating tins or bottles
- B01F29/32—Containers specially adapted for coupling to rotating frames or the like; Coupling means therefor
- B01F29/321—Containers specially adapted for coupling to rotating frames or the like; Coupling means therefor of test-tubes or the like
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/80—Mixers with rotating receptacles rotating about a substantially vertical axis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00534—Mixing by a special element, e.g. stirrer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0439—Rotary sample carriers, i.e. carousels
- G01N2035/0446—Combinations of the above
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0474—Details of actuating means for conveyors or pipettes
- G01N2035/0475—Details of actuating means for conveyors or pipettes electric, e.g. stepper motor, solenoid
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention provides a reagent blending device comprising a driving device, a transferring device and a rotating part. The transferring device comprises a conveying mechanism for conveying a reagent box and a blending mechanism for blending reagents, the driving device drives the conveying mechanism and the blending mechanism to move relatively, the rotating part and the blending mechanism are in transmission fit, and the conveying mechanism is sleeved with the blending mechanism to form a bearing structure. The invention further provides a reagent blending method. The blending device is small in size, ingenious in structure, easy to assemble, and low in manufacturing cost. The blending mode is simple and reliable, complete machine operation is high in reliability, and the reagent blending device has high application value in the analysis and detection fields of a full-automatic chemiluminiscence immunity analyzer, a biochemical analyzer and the like.
Description
Technical field
The present invention relates to a kind of reagent evenly mixing device and mixing method, particularly relate to the reagent mixing conveyer for chemical illumination immunity analysis instrument.
Background technology
Fully-automated synthesis analyser automatically can complete from application of sample, reagent adding, reaction, detects, go out the sequence of operations steps such as testing result.Adopt fully-automated synthesis analyser to determine the content of certain composition in tested sample, become very general.Such as Full-automatic chemiluminescence immunoassay analysis meter, comprises sample storehouse, agent bin, reaction warehouse and detection storehouse.The testing process of analyser roughly comprises: first sample and reagent are put into sample storehouse and agent bin respectively, then sample and reagent are joined in reaction cup, make reaction cup respectively through systems such as incubation, separation, cleanings again, finally make reaction cup enter airtight darkroom and complete mensuration.
Chemiluminescence immune assay (chemiluminescenceimmunoassay, CLIA), combine having highly sensitive chemical luminescent detecting technology with the immune response of high specific, so as to quantitatively detecting the analytical technology of various antigen, haptens, antibody, hormone, enzyme, fatty acid, vitamin and medicine etc.Need plurality of reagents in chemiluminescence immune assay, comprising solid-phase reagent, conventional solid-phase reagent is the magnetic particle of mark.Require during use that magnetic particle reagent concentration is evenly distributed, and magnetic particle easily precipitates under gravity, causes uneven.If participate in stability and reliability that correlated response will have a strong impact on test result after magnetic particle reagent precipitates again.So needed to be mixed before use magnetic particle reagent.
Current Full-automatic chemiluminescence immunoassay analysis meter adopts rabbling mechanism to stir and evenly mix magnetic particle reagent, but this mode not only mixing time length, weak effect, and be very easy to form cross pollution.And handle up with high frequency or concussion method mixing magnetic particle reagent, the requirement that the magnetic particle reagent in multiple kit mixes simultaneously can not be met, the detection speed of fully-automatic analyzer can be reduced.Adopting transmission to coordinate in the method for mixing magnetic particle reagent, analytical instrument comprises kit transport unit and magnetic particle reagent mixing portion.Fully-automatic analyzer can according to the needs of test item, and by transport unit, corresponding kit is transported to the reagent collection position of analyser, in the process of transporting kit, magnetic particle reagent mixes by the mode that mixing portion is coordinated by transmission.But in existing design, transport unit and mixing part belong to separate movement system.The structure of these relatively independent dispersions, can reduce operation accuracy and the reliability of analyser, increases the complicacy of analyser assembling and the cost of the manufacturing.The module of physical construction is complicated and various, also can increase the volume of analyser itself, make analyser very huge, need to take more lab space.
In existing fully-automated synthesis analyser, the cooperation between kit and kit bracket, needs by the complicated fit structure part such as hook member usually to keep the position of kit on kit bracket.Thus not only consuming time in manufacture kit and kit bracket process, and cost is high.Between kit and bracket, structure is not compact, and volume is large.Can mechanical noise be produced between assembling fittings, the accuracy of detection of impact analysis instrument, and increase follow-up maintenance difficulty and cost.
At detection analysis field, often need to use plurality of reagents to go the detection of a project.When utilizing fully-automated synthesis analyser test item, plurality of reagents can be integrated in a kit, and this kit is put into fully-automatic analyzer.Have multiple reagent bottle storage chamber in kit, different reagent is installed in different reagent bottles.These reagent bottles that reagent is housed are put into kit storage chamber in advance.
When detecting different projects, need to change the kit in analyser.Or the reagent in kit has been used up, also need to change kit.Use the kit not having handle, operator must catch the body of kit kit could be taken out.If kit discharges very tight in analyser, namely kit is close to mutually, and the space leaving operator's finger grip kit like this for is little, and this allows the taking-up of kit become very inconvenient.And some kit additionally can increase a handle, although operator extracts kit and becomes very convenient, due to the existence of handle, it needs to take the certain space of instrument, adds the overall volume of instrument.This not only increases the material cost of instrument, also therefore can take more lab space.
According to the needs that medical science detects, a sample has needed multiple test item sometimes.Such as analyze patient and whether there is certain communicable disease, just need to carry out the sample of patient the detection of HSV-I, HSV-II, RV, HCMV and TOXO in HBsAg, HBsAb, HBeAg, HBeAb, HBcAb, HCV, ToRCH series, Chlamydia, Gonorrhea, HIV, Syphilis etc.Analyze in clinical samples and whether there is tumor markers, need test example as PSA, Cyfra21-1, AFP, CEA, NSE, CA19-9, CA15-3, CA72-4, CA125, CA50, ProGRP, Fer, TPS, GPC3 etc.Whether there is Drug Abuse to understand detected person, the test item of needs comprises MOP, AMP, BAR, COC, MET, THC, BZO, MDMA, MTD, OPI, PCP etc.Different test items needs to use different detection reagent.Therefore the agent bin in fully-automatic analyzer is needed disposablely can to put into abundant kit, with the requirement of satisfied detection.If it is insufficient that the kit of agent bin deposits position, same detection series can be caused, such as, when infectious disease series detects, need in batches the detection kit of correspondence to be put into analyser and complete detection in batches.First put into analyser by detecting the kit of HBsAg, HBsAb, HBeAg, HBeAb, HBcAb, HCV, Chlamydia, Gonorrhea, now the kit of the agent bin of analyser is deposited position and is piled, then start detection.After first project has detected, take out the kit that first uses, and then put into the detection kit of HSV-I, HSV-II, RV, HCMV, TOXO, Chlamydia, Gonorrhea, HIV, Syphilis of ToRCH series.This have impact on the progress analyzed and detect.
Summary of the invention
In order to the problems of the prior art solved, the invention provides a kind of reagent mixing conveyer, comprise drive unit, transporter and tumbler, transporter comprises the mixing mechanism of conveyer and the mixing reagent transporting kit, drive unit drives conveyer and mixing mechanism to produce relative motion, between tumbler and mixing mechanism, transmission coordinates, and described conveyer and mixing mechanism connect together composition bearing arrangement mutually.
Further, conveyer and mixing mechanism are circular ring structure, and conveyer is arranged in the center pit of mixing mechanism.
Further, drive unit comprises drive motor and drive end, and drive end is arranged in the center pit of conveyer.
Further, the kind of drive between described drive end and conveyer is selected from meshed transmission gear, friction gearing, pulley drive; The kind of drive between mixing mechanism and tumbler is from meshed transmission gear, friction gearing.
Further, conveyer is inner gear structure, and mixing mechanism is outer rotor structure, drive end is provided with driving tooth bar, the annular wheel of described driving tooth bar and conveyer engages each other, and described tumbler is gear, and the outer rotor of described tumbler gear and mixing mechanism engages each other.
Further, conveyer comprises pedestal and mount pad, and pedestal and mixing mechanism interconnect in the mode of bearing, and mount pad is arranged on described pedestal, mount pad includes the driving member coordinated with drive unit.
Present invention also offers a kind of detection reagent mixing method, comprise the following steps:
(1) a kind of reagent is provided to mix conveyer;
(2) be placed on described reagent mixing conveyer by being equipped with the kit that need mix reagent;
(3) reagent mixing conveyer is started, mixing reagent;
Wherein, described reagent mixing conveyer comprises drive unit, transporter and tumbler, transporter comprises the mixing mechanism of conveyer and the mixing reagent transporting kit, drive unit comprises drive motor and drive end, drive end is arranged in the center pit of conveyer, drive unit drives conveyer and mixing mechanism to produce relative motion, between tumbler and mixing mechanism, transmission coordinates, tumbler is for stirring the reagent that need mix, and described conveyer and mixing mechanism connect together composition bearing arrangement mutually.
Further, conveyer and mixing mechanism are circular ring structure, and conveyer is arranged in the center pit of mixing mechanism.
Further, conveyer is inner gear structure, and mixing mechanism is outer rotor structure, drive end is provided with driving tooth bar, the annular wheel of described driving tooth bar and conveyer engages each other, and described tumbler is gear, and the outer rotor of described tumbler gear and mixing mechanism engages each other.
Further, drive unit drives conveyer and mixing mechanism to produce relative motion, the reagent that corresponding kit is transported to analyser by conveyer gathers position, simultaneously along with the rotation of conveyer, transmission is produced between the tumbler mixed for reagent and mixing mechanism, there is rotation in reagent bottle, the reagent be contained in this reagent bottle is mixed because of rotation under mixing mechanism and tumbler transmission in kit.
Reagent of the present invention mixing conveyer volume is little, and structure is ingenious, simple and reliable, easily assemble, and complete machine operational reliability is high, low cost of manufacture.And magnetic particle blending manner of the present invention is simple and reliable, Blending Efficiency of Blending is good, can mix several magnetic particle reagent without cross contamination risk simultaneously.
Detection reagent storage device of the present invention efficiently utilizes space, increases reagent storage amount.By the cooperation of keeper and positioning port between kit and kit bracket, kit more firmly can be placed in agent bin, this matching mechanism effectively can reduce the shake of kit, reduces the noise of analyser.
The fit structure of the shackle member of reagent bottle of the present invention and kit, while mentioning reagent bottle, just can mention kit box body together, maintain the balance of whole box body, and is unlikely to because tilt, and the danger that reagent topples over out occurs.
Accompanying drawing explanation
The schematic diagram that Fig. 1 kit box body is separated with reagent bottle.
Fig. 2 kit box body schematic diagram together with reagent bottle combination.
Fig. 3 kit puts into the schematic diagram of kit bracket.
The schematic diagram that the keeper that Fig. 4 shifts to install coordinates with the positioning port on bracket.
The schematic diagram that the keeper of the corresponding setting of Fig. 5 coordinates with the positioning port on bracket.
Fig. 6 kit only has a schematic diagram sidewall being provided with keeper and coordinating with the positioning port of bracket.
Fig. 7 projection puts into the vertical view of kit box body along fastener passage.
Fig. 8 projection turns to the vertical view under lid eaves.
Fig. 9 projection puts into the Local map of kit box body along fastener passage.
Figure 10 projection turns to the Local map under lid eaves.
The schematic diagram that on Figure 11 reagent bottle, L-type structural member coordinates with inverted concave structural member in box body.
The schematic diagram that on Figure 12 reagent bottle, buckling piece coordinates with buckling groove in box body.
Figure 13 reagent storage device and reagent mix the schematic diagram that conveyer coordinates.
Figure 14 reagent mixing conveyer schematic diagram.
Figure 15 reagent mixing conveyer schematic diagram.
Figure 16 agent bin vertical view.
Figure 17 is the agent bin cut-open view in Figure 16 A-A direction.
Figure 18 puts into the agent bin schematic diagram of kit.
Figure 19 is with the agent bin schematic diagram of refrigerating plant.
The inner structure schematic diagram of Figure 20 Full-automatic chemiluminescence immunoassay analysis meter.
Figure 21 Full-automatic chemiluminescence immunoassay analysis meter schematic diagram.
Figure 22 removes the Full-automatic chemiluminescence immunoassay analysis meter of sample storehouse side shield.
Embodiment
Further describe the present invention below in conjunction with drawings and Examples, but protection scope of the present invention is not limited to this.
A kind of Full-automatic chemiluminescence immunoassay analysis meter 9000, comprises sample storehouse 9300, agent bin 9400, reaction cup storage warehouse 9500, hatches storehouse 9600, clean storehouse 9700 and detect storehouse 9800 as shown in Figure 20 to 22.When sample to be tested carries out constituent analysis, first sample and reagent are put into sample storehouse and agent bin respectively, Full-automatic chemiluminescence immunoassay analysis meter takes out reaction cup from reaction cup storage warehouse 9500, and puts it into and hatch in storehouse.Then by preset program, sample and reagent are joined in reaction cup, start and hatch program, cleaning procedure, finally make reaction cup enter detection storehouse and complete sample component analysis.Wherein said sample storehouse comprises identity information reading device, and described agent bin comprises reagent mixing conveyer.
As illustrated in fig. 1 and 2, box body 2 and mixing chamber 3 is comprised for depositing the kit 1 detecting reagent, need the reagent of mixing when described mixing chamber 3 is for depositing detection, described reagent can directly load in this mixing chamber, or puts into mixing chamber 3 after loading reagent bottle in advance again.If needed, kit can also comprise storage chamber 4, and require not too high reagent to mixing when described storage chamber 4 is for depositing detection, described reagent can directly load in this storage chamber, or puts into storage chamber 4 again after loading reagent bottle in advance.
In the embodiment shown in fig. 1, the reagent that need mix loads in mixing reagent bottle 5 in advance, and described mixing reagent bottle 5 is provided with tumbler 6.The mixing reagent bottle 5 that reagent is housed puts into the mixing chamber 3 of kit, has driven mixing reagent bottle 5 to rotate in mixing chamber 2, make the reagent in reagent bottle 5 because rotate and be in suspension mixing state when tumbler 6 rotates.Tumbler 6 can be the structure that mixing reagent bottle 5 carries, and namely as shown in Figure 1 before reagent bottle 5 puts into mixing chamber, tumbler 6 has inherently been arranged on reagent bottle 5.Tumbler 6 can also be independent parts, and after mixing reagent bottle 5 puts into mixing chamber 3, mixing reagent bottle coordinates with tumbler, thus reagent bottle 5 and tumbler 6 is fitted together.When tumbler is as separate part, it can be arranged on kit, or be arranged on the matching used instrument of kit.In the embodiment depicted in figure 2, after reagent bottle 5 puts into mixing chamber 3, tumbler 6 is positioned at breach 31 place in mixing chamber 3.
The chamber wall in kit storage chamber and/or mixing chamber is provided with positioning port 104, correspondingly on reagent bottle 11 tube wall is provided with keeper 7.Before reagent bottle being put into storage chamber and/or mixing chamber, first reagent bottle keeper 7 is aimed at positioning port 104, then allow reagent bottle down enter in containing cavities and/or mixing chamber, can be accurately placed in containing cavities and/or mixing chamber by guarantee reagent bottle like this.The upper surface of keeper 7 is concordant with the upper surface of reagent bottle, and the degree of depth of positioning port 104 is identical with the depth degree of depth of keeper 7.After reagent bottle keeper inserts along positioning port, if the upper surface of keeper is concordant with the upper surface of positioning port, this illustrates that reagent bottle is put into position exactly.
In another embodiment, the inwall of storage chamber also comprises a shell fragment, for clamping the reagent bottle be placed in storage chamber.
At detection field, such as, during chemiluminescence immunoassay detects, the detection completing a project needs plurality of reagents, comprises the reagent of band solid phase, such as, reagent containing magnetic particle.Therefore select the kit with mixing chamber 3 and multiple storage chamber 4 of the present invention, described mixing reagent bottle put into by the reagent that magnetic particle is housed.
During detection, kit corresponding for test item is put into analyser.In one embodiment, analyser comprises the kit bracket for carrying kit, according to the kind of test item, the detection kit of correspondence is put into the relevant position of described kit bracket, start the detection that once can complete multiple project with Realization analysis instrument.
Kit bracket 100 as shown in Figure 3 comprises inner ring 101 and dividing plate 102, and dividing plate is arranged on inner ring, and form the containing cavities 103 that a horizontal section is fan annular between two dividing plates 102, containing cavities is for placing kit 1.In one embodiment, the number of containing cavities 103 is arranged in mode kit bracket being received most volume kit.Such set-up mode, can meet more test item, in series detects, does not just need to put kit at twice.
In one embodiment, the upper edge of kit bracket dividing plate 102 is provided with positioning port 104, and kit is as shown in Figure 2 provided with keeper 7 corresponding to dividing plate positioning port 104 place.Before kit being put into the containing cavities of bracket, first kit keeper is aimed at positioning port, then kit is allowed down to enter in containing cavities, can be accommodated in containing cavities 103 exactly by guarantee reagent box like this, when ensure that testing process gathers reagent, the liquid device of adopting of analyser can enter reagent storage chamber like clockwork or mix in chamber, and is unlikely to adopt the upper cover that kit encountered by liquid device, has damaged and has adopted liquid device.In another embodiment, in order to reduce analyser weight, kit bracket containing cavities is up/down perforation, does not arrange the base plate for supporting kit bottom containing cavities.Therefore the cooperatively interacting of keeper and positioning port, has an effect supported to the kit be placed in containing cavities 103.The depth degree of depth of keeper 7 is identical with the degree of depth of positioning port 104, and after kit puts into containing cavities, if the upper surface of keeper is concordant with the upper surface of positioning port, this illustrates that kit is put into position, meets the requirement that analyser runs.In embodiment as shown in Figures 1 to 3, the upper surface 71 of keeper 7 is concordant with the upper surface 8 of kit, and the degree of depth of positioning port 104 is identical with the depth degree of depth of keeper 7.After kit keeper inserts along positioning port, if the upper surface of keeper 71 is concordant with the upper surface of positioning port, this illustrates that kit is put into position.The design that the upper surface 71 of keeper 7 is concordant with the upper surface 8 of kit, can allow operator observe kit more easily and whether be put into position.
In one embodiment, the interlaced arrangement of keeper on kit two side.Specifically, kit the first side wall is provided with keeper, the keeper on kit second sidewall is not arranged on the corresponding position of the first side wall keeper.Further illustrate, as shown in Figure 1, kit sidewall comprises interposition keeper 72, another sidewall of kit comprises left keeper 73 and right keeper 74, left and right keeper lays respectively at the corresponding both sides of interfix part.As shown in Figure 4, method according to the present embodiment, three pieces of dividing plates 102 with identical positioning port 104 set-up mode constitute two containing cavities 103, after two kits 1 with identical keeper set-up mode put into described containing cavities, two kits lean against the both sides of same dividing plate closely.The interfix part 72 of the first kit and left keeper 73 ˊ of the second kit and right keeper 74 ˊ coordinate with dividing plate positioning port interlacedly.The left keeper 73 of the first kit and right keeper 74 and the 3rd kit interfix part 72 " coordinate with dividing plate positioning port interlacedly.Interfix part 72 ˊ of the second kit is staggered with the left and right keeper of the 4th kit again.Such design proposal reduces the usage quantity of dividing plate, thus reduces the volume of analyser.And kit two side all has membrane support, ensure that the shelf stability of kit in containing cavities.Design compared to Fig. 5 embodiment illustrated in fig. 4, often deposit two kits, kit bracket just can less with one piece of dividing plate, thus reduces the space that kit bracket takies, also allow kit bracket because reduce dividing plate number, and vacate more space and deposit more kit.The keeper 7 of the kit two side shown in Fig. 5 is mutually corresponding setting, when two kits put into containing cavities, must use four pieces of dividing plates 102.Execute the design of example compared to Fig. 6 shown in Fig. 4, kit is deposited more stable.As shown in Figure 6, in order to the containing cavities realizing three pieces of dividing plate compositions can put down two kits, kit is only provided with keeper 7 on a sidewall.After kit puts into containing cavities 103, do not have the kit side of keeper not have dividing plate 102 to support, this makes kit be placed in containing cavities is very built on the sand.
Kit bracket inner ring also can comprise kit positioning and guiding groove 105, kit is provided with guide 9.When kit puts into containing cavities, guide 9 is inserted in gathering sill 105, and moves down along gathering sill.The matching design of gathering sill and guide, allows kit can put into containing cavities quickly and accurately.In embodiment as shown in Figures 2 and 3, gathering sill 105 is positioned at the centre position of two dividing plates, and guide 9 is positioned at the outer middle side part of the narrow end of kit.In another embodiment, guide is also provided with stop block 10, the width of stop block is greater than the width of rebate of gathering sill.As shown in Figure 3, after guide 9 is inserted into gathering sill, stop block 10 is positioned at the outside of gathering sill 105, further defines the position of kit in containing cavities.
The inner side of kit bracket inner ring also can comprise a reinforced wall 106, and described reinforced wall 106 is guarantee reagent box bracket shape further, such as circular.In analyser operational process, the kit bracket of dimensionally stable, can guarantee reagent sampling accuracy.After kit puts into containing cavities, the upper surface of described reinforced wall 106 bottom stop block 10, can also be resisted against, play the effect supporting kit further.
For the reagent storage device of full-automatic vitro diagnosis assays instrument, comprise kit 1 of the present invention and kit bracket 100.Kit bracket comprises containing cavities 103, and the number of described containing cavities 103 is arranged in the mode this kit bracket being received most volume kit.Kit comprises reagent storage chamber 4 and/or mixing chamber 3.The number in described storage chamber 4 and/or mixing chamber 3 and its volume are arranged in the mode this kit being received maximum kind reagent and/or maximum reagent storage amount.At kit as shown in Figure 1, comprise the reagent mixing chamber 3 that three circular reagent storage chambeies 4 and 1 are positioned at the narrow end of kit.Be provided with the larger storage chamber of diameter at the middle part of kit, kit wide end place is arranged side by side the identical storage chamber of two diameters.Described storage chamber is tangent with the inwall of the outward flange and kit that mix chamber.In one embodiment, storage chamber fills up whole kit.
In one embodiment, the horizontal section of containing cavities and kit is fan annular.The number of containing cavities and the number in reagent storage chamber are combined, and the amount of reagent that reagent storage device can be deposited reaches the maximal value that reagent storage device can deposit amount of reagent.
In one embodiment, described reagent bottle 11 comprises fastener, described storage chamber 4 comprises block piece.Block piece is for stopping that fastener leaves storage chamber.When block piece stops fastener, while mentioning reagent bottle, just kit box body can be mentioned together.Keep the balance of whole box body, and be unlikely to tilt, the danger that reagent topples over out occurs.
In embodiment as shown in Fig. 1 and Fig. 7 to 10, kit 1 comprises box body 2 and storage chamber 4, and storage chamber is for depositing reagent or the reagent bottle of reagent being housed.Described reagent bottle 11 comprises fastener, described storage chamber 4 comprises block piece and fastener passage 12.In one embodiment, described fastener is the projection 13 be arranged on reagent bottle outer wall.Block piece is the lid eaves 14 of box body upper cover, and described lid eaves belongs to a part for box body upper cover, lid eaves 14 than the inwall of storage chamber 3 closer to the center of storage chamber xsect.Described fastener Channel 12-Bit is in upper cover place, and adjacent with block piece.Projection 13 is entered by fastener passage 12 or leaves storage chamber.As shown in figures 7 and 9, when needs put into reagent bottle 11 in box body 1, first the projection 13 on reagent bottle is aimed at fastener passage 12, then reagent bottle is toward transferring in storage chamber.As shown in figures 8 and 10, after reagent bottle arrives the position preset, rotate reagent bottle, the projection 13 (i.e. fastener) on reagent bottle is turned to the below of lid eaves 14 (i.e. block piece), now reagent bottle just can not leave from box body.When mentioning reagent bottle, box body is also raised together, then just kit can be put into analytical instrument, or take out from analytical instrument.When projection is gone to fastener passage 12 place by rotation reagent bottle, make projection 13 no longer be positioned at the below of lid eaves 14, thus reagent bottle can shift out from box body.In a preferred version, the tail end of described projection comprises a stop member 131, and the height of described stop member is higher than the bottom surface of lid eaves.When projection turns to the below of lid eaves, stop member will by lid eaves, thus determines that projection forwards position to.
In embodiment as shown in figure 11, described fastener is L-type structural member 15, and described block piece is inverted concave structural member 16.After reagent bottle arrives the position preset, rotate reagent bottle, turn in inverted concave structural member 16 by the L-type structural member 15 on reagent bottle, now reagent bottle just can not leave from box body.While mentioning reagent bottle, just box body can be mentioned together.
In embodiment as shown in figure 12, described fastener is a buckling piece, and buckling piece comprises elasticity snap arm 17 and card base 18, and one end of snap arm 17 is arranged on the outer wall of reagent bottle.Described block piece is buckling groove 19.When reagent bottle is put into storage chamber, snap arm 17 is pressed to reagent bottle outer wall, and descending along the riser 20 of buckling groove 19, and until card base 18 snaps in buckling groove 19, the riser 20 of buckling piece stops card base upwards to shift out storage chamber.When reagent bottle changed by needs, as long as again snap arm 17 is pressed to reagent bottle outer wall, make card base 18 leave buckling groove 19, thus reagent bottle can be taken out from box body.
Reagent mixing conveyer comprises transporter and drive unit, and transporter comprises conveyer 201 and mixing mechanism 202, and conveyer 201 and mixing mechanism 202 connect together composition bearing arrangement mutually.Kit for placing kit, and is sent to the relevant position of analyser by conveyer.Mixing mechanism 202 coordinates with tumbler 6, for mixing the reagent of the needs mixing in kit.Drive unit comprises drive end 301 and power part 302.Drive unit drives conveyer 201 and mixing mechanism to produce relative motion, is used between the tumbler 6 of reagent mixing and mixing mechanism 202 and produces transmission, thus realize the transhipment and the mixing that detect reagent.
In embodiment as shown in Figure 13 to 17, conveyer 201 and mixing mechanism 202 are circular ring structure, and conveyer is arranged in the center pit of mixing mechanism, and both fit together mutually becomes a bearing arrangement.In embodiment as shown in figure 15, between conveyer 201 and mixing mechanism 202, be provided with ball 203.Mixing mechanism is fixedly mounted on analyser.The drive end 301 of drive unit is arranged in the center pit of conveyer.In one embodiment, conveyer 201 is inner gear structure, and mixing mechanism 202 is outer rotor structure, drive end 301 is provided with driving tooth bar, and described driving tooth bar engages with the annular wheel of conveyer, and power part 302 is motor.Comprise the mixing reagent bottle 5 of bottom with tumbler 6 in kit mixing chamber as shown in Figure 2, reagent bottle is built with the magnetic particle reagent needing mixing, and described tumbler 6 is gear structure.When kit 1 is positioned on conveyer 201, be installed on the gear (tumbler) bottom reagent bottle and engage each other with the outer rotor of mixing mechanism 202.Opening motor makes drive end rotate, and drive end drives conveyer to rotate, and the kit be placed on conveyer also rotates thereupon together, makes the outer rotor of gear and mixing mechanism produce transmission.There is rotation with the reagent bottle of tumbler in bottom, the reagent be contained in reagent bottle is mixed because of rotation under mixing mechanism and tumbler engaged transmission.In the present embodiment, mixing mechanism is fixedly mounted on analyser, and mixing mechanism can not rotate, and conveyer rotates around the central shaft of mixing mechanism.In another scheme, conveyer and mixing mechanism can also rotate around same central shaft is relative.
The kind of drive between described drive end 301 and conveyer 201 can also be selected from the modes such as meshed transmission gear, friction gearing, pulley drive.The kind of drive between mixing mechanism 202 and tumbler 6 can also from the mode such as meshed transmission gear, friction gearing.
Conveyer and mixing mechanism are fitted together with bearing arrangement form, conveyer and the friction factor of mixing mechanism in motion process can be reduced, lower mechanical noise when machine runs, reduce the energy consumption that analyser runs, extend the serviceable life of analyser.Respectively conveyer and mixing mechanism are installed to analyser step by step compared to needing in prior art, conveyer of the present invention and mixing mechanism integrally can be installed on analyser, this makes installation simple, convenient, is conducive to regular maintenance, cleaning, replacing.And effectively can ensure that conveyer and mixing mechanism surface level keep mutual parastate, thus guarantee that both position relationships are stablized, keep higher dynamic equilibrium state, improve the running precision of analyser.In long-term operational process, the cooperation of tumbler and mixing machine component is stablized, the phenomenon of beating tooth is less likely to occur.Conveyer and mixing mechanism are assembled into bearing arrangement, and on analyser, corresponding assembly parts will reduce, thus save the installing space of analyser parts.Drive end is arranged in conveyer center pit, make use of the idle space of analyser well, makes the volume of analyser entirety become less.
In another embodiment, mixing mechanism 202 is arranged in the center pit of conveyer 201, and both fit together mutually becomes bearing arrangement.Conveyer 201 is outer rotor structure, and mixing mechanism 202 is inner gear structure, and drive end is arranged on the outer side edges of conveyer.
In one embodiment, conveyer comprises pedestal and mount pad, and pedestal is positioned at the center pit of mixing mechanism, and interconnects in the mode of bearing with mixing mechanism, and mount pad is arranged on described pedestal, and mount pad is for placing kit.Mount pad includes the driving member coordinated with drive end.Drive end drive installation seat rotates, and mount pad drives conveyer to rotate relative to mixing mechanism, and the kit be placed on mount pad also rotates thereupon together, makes tumbler and mixing mechanism produce transmission.There is rotation with the reagent bottle of tumbler in bottom, the reagent be contained in reagent bottle is mixed because of rotation under mixing mechanism and tumbler transmission.In another embodiment, conveyer does not comprise the driving member coordinated with drive end, mixing mechanism does not comprise the driving member coordinated with tumbler, and conveyer and mixing mechanism fit together mutually becomes bearing arrangement.Described driving member, such as gear, friction block, as independently parts, be arranged on the relevant position of conveyer and mixing mechanism respectively.
The agent bin 400 of fully-automatic analyzer comprises reagent storage device and reagent mixing conveyer.Described reagent mixing conveyer comprises transporter and drive unit, and transporter comprises conveyer 201 and mixing mechanism 202, and conveyer 201 and mixing mechanism 202 connect together composition bearing arrangement mutually.Reagent storage device comprises kit and kit bracket, and described kit bracket 100 is arranged on described conveyer 201, and kit 1 puts into kit bracket 100.With the tumbler 6 that the reagent bottle that mixes reagent is connected be housed cooperatively interact with the driving member of mixing mechanism 202.Drive unit comprises drive end 301 and power part 302.When reagent mixing conveyer runs, drive unit drives conveyer 201 and mixing mechanism to produce relative motion, is transported to by kit and detects corresponding position.Simultaneously along with the rotation of conveyer, produce transmission between the tumbler mixed for reagent and mixing mechanism, there is rotation in reagent bottle, the reagent be contained in this reagent bottle is mixed because of rotation under mixing mechanism and tumbler transmission in kit.
As depicted in figs. 18-19 agent bin 400 also comprise heat-insulation layer 401 and Cang Gai, make agent bin be in relatively insulation and airtight state.Reagent storage device surrounds within it by heat-insulation layer, keeps the reagent in agent bin to be in temperature constant state.Described agent bin also comprises agent bin refrigerating plant 403, for the refrigeration of agent bin.In one embodiment, semiconductor chilling plate elected as by described refrigerating plant.In one embodiment, refrigerating plant is arranged at the bottom of the storehouse of agent bin.Agent bin also comprises reagent bottle null pick-up 404, for judging the initial position of agent bin.
A kind of reagent mixing method of fully-automatic analyzer, first puts into agent bin by being equipped with the kit detecting reagent, and is positioned on kit bracket of the present invention.Described kit bracket and reagent of the present invention mix conveyer and cooperatively interact.When reagent mixing conveyer runs, the drive unit of fully-automatic analyzer drives conveyer 201 and mixing mechanism to produce relative motion, and according to the needs of test item, corresponding kit is transported to the reagent collection position of analyser by conveyer.Simultaneously along with the rotation of conveyer, produce transmission between the tumbler mixed for reagent and mixing mechanism, there is rotation in reagent bottle, the reagent be contained in this reagent bottle is mixed because of rotation under mixing mechanism and tumbler transmission in kit.
Claims (10)
1. reagent mixing conveyer, comprise drive unit, transporter and tumbler, transporter comprises the mixing mechanism of conveyer and the mixing reagent transporting kit, drive unit drives conveyer and mixing mechanism to produce relative motion, between tumbler and mixing mechanism, transmission coordinates, it is characterized in that, described conveyer and mixing mechanism connect together composition bearing arrangement mutually.
2. reagent mixing conveyer according to claim 1, it is characterized in that, conveyer and mixing mechanism are circular ring structure, and conveyer is arranged in the center pit of mixing mechanism.
3. reagent mixing conveyer according to claim 1, it is characterized in that, drive unit comprises drive motor and drive end, and drive end is arranged in the center pit of conveyer.
4. reagent mixing conveyer according to claim 3, it is characterized in that, the kind of drive between described drive end and conveyer is selected from meshed transmission gear, friction gearing, pulley drive; The kind of drive between mixing mechanism and tumbler is from meshed transmission gear, friction gearing.
5. reagent mixing conveyer according to claim 3, it is characterized in that, conveyer is inner gear structure, mixing mechanism is outer rotor structure, drive end is provided with driving tooth bar, the annular wheel of described driving tooth bar and conveyer engages each other, and described tumbler is gear, and the outer rotor of described tumbler gear and mixing mechanism engages each other.
6. reagent mixing conveyer according to claim 1, it is characterized in that, conveyer comprises pedestal and mount pad, and pedestal and mixing mechanism interconnect in the mode of bearing, mount pad is arranged on described pedestal, mount pad includes the driving member coordinated with drive unit.
7. detect reagent mixing method, comprise the following steps:
(1) a kind of reagent is provided to mix conveyer;
(2) be placed on described reagent mixing conveyer by being equipped with the kit that need mix reagent;
(3) reagent mixing conveyer is started, mixing reagent;
Wherein, described reagent mixing conveyer comprises drive unit, transporter and tumbler, transporter comprises the mixing mechanism of conveyer and the mixing reagent transporting kit, drive unit comprises drive motor and drive end, drive end is arranged in the center pit of conveyer, drive unit drives conveyer and mixing mechanism to produce relative motion, between tumbler and mixing mechanism, transmission coordinates, tumbler is for stirring the reagent that need mix, and described conveyer and mixing mechanism connect together composition bearing arrangement mutually.
8. method according to claim 7, is characterized in that, conveyer and mixing mechanism are circular ring structure, and conveyer is arranged in the center pit of mixing mechanism.
9. method according to claim 7, it is characterized in that, conveyer is inner gear structure, mixing mechanism is outer rotor structure, drive end is provided with driving tooth bar, the annular wheel of described driving tooth bar and conveyer engages each other, and described tumbler is gear, and the outer rotor of described tumbler gear and mixing mechanism engages each other.
10. according to the method one of claim 7-9 Suo Shu, it is characterized in that, drive unit drives conveyer and mixing mechanism to produce relative motion, the reagent that corresponding kit is transported to analyser by conveyer gathers position, simultaneously along with the rotation of conveyer, produce transmission between the tumbler mixed for reagent and mixing mechanism, there is rotation in reagent bottle, the reagent be contained in this reagent bottle is mixed because of rotation under mixing mechanism and tumbler transmission in kit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510961493.XA CN105510613A (en) | 2015-12-21 | 2015-12-21 | Reagent blending conveying device and blending method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510961493.XA CN105510613A (en) | 2015-12-21 | 2015-12-21 | Reagent blending conveying device and blending method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105510613A true CN105510613A (en) | 2016-04-20 |
Family
ID=55718739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510961493.XA Pending CN105510613A (en) | 2015-12-21 | 2015-12-21 | Reagent blending conveying device and blending method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105510613A (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018032719A1 (en) * | 2016-08-17 | 2018-02-22 | 江苏英诺华医疗技术有限公司 | Fully-automatic biochemical analyzer with non-contact pneumatic mixing device, and method of analysis |
| CN108201837A (en) * | 2018-03-19 | 2018-06-26 | 杨雪锋 | A kind of medical tubes automatic mixing device |
| CN108872078A (en) * | 2018-06-29 | 2018-11-23 | 广州市进德生物科技有限公司 | A kind of Full-automatic chemiluminescence analyzer |
| CN109261040A (en) * | 2018-12-04 | 2019-01-25 | 希肯医疗技术（苏州）有限公司 | A kind of poly functional reagent pot |
| CN109358201A (en) * | 2018-10-16 | 2019-02-19 | 基蛋生物科技股份有限公司 | Full-automatic chemiluminescence immunoassay analysis meter |
| CN110554181A (en) * | 2018-05-30 | 2019-12-10 | 深圳市帝迈生物技术有限公司 | Kit and reagent dish device |
| CN111000467A (en) * | 2019-12-28 | 2020-04-14 | 黄赛士 | A even stirring adder of misce bene for safety in production |
| CN111514789A (en) * | 2020-04-15 | 2020-08-11 | 林水彬 | Quick dispensing device that medical care used |
| WO2020215175A1 (en) * | 2019-04-22 | 2020-10-29 | 深圳迈瑞生物医疗电子股份有限公司 | Magnetic bead reagent uniform mixing apparatus, uniform mixing method, and sample analysis device |
| US11255846B2 (en) | 2017-03-01 | 2022-02-22 | Leadway (Hk) Limited | Reagent mixing and conveying device and reagent mixing method |
| EP4059592A1 (en) * | 2021-03-16 | 2022-09-21 | Swissmeca SA | Sample tube and device and method for dispersing and homogenizing |
| WO2022227724A1 (en) * | 2021-04-28 | 2022-11-03 | 深圳市亚辉龙生物科技股份有限公司 | Reagent mixing and loading device and immunological detection apparatus |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07260794A (en) * | 1994-03-23 | 1995-10-13 | Omron Corp | Stirring mechanism of sample preparation device |
| CN101799478A (en) * | 2010-03-12 | 2010-08-11 | 郑州博赛生物技术股份有限公司 | Reagent tray device for automatic immunity analyzer |
| CN102128939A (en) * | 2010-12-31 | 2011-07-20 | 安图实验仪器(郑州)有限公司 | Regent tray |
| CN103235148A (en) * | 2013-04-25 | 2013-08-07 | 深圳市国赛生物技术有限公司 | Reagent disk |
| CN203170251U (en) * | 2013-04-16 | 2013-09-04 | 深圳迈瑞生物医疗电子股份有限公司 | Reagent bottle |
| CN103472242A (en) * | 2013-10-14 | 2013-12-25 | 中国科学院苏州生物医学工程技术研究所 | Kit conveying device used for full-automatic chemiluminescence immunoassay instrument |
-
2015
- 2015-12-21 CN CN201510961493.XA patent/CN105510613A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07260794A (en) * | 1994-03-23 | 1995-10-13 | Omron Corp | Stirring mechanism of sample preparation device |
| CN101799478A (en) * | 2010-03-12 | 2010-08-11 | 郑州博赛生物技术股份有限公司 | Reagent tray device for automatic immunity analyzer |
| CN102128939A (en) * | 2010-12-31 | 2011-07-20 | 安图实验仪器(郑州)有限公司 | Regent tray |
| CN203170251U (en) * | 2013-04-16 | 2013-09-04 | 深圳迈瑞生物医疗电子股份有限公司 | Reagent bottle |
| CN103235148A (en) * | 2013-04-25 | 2013-08-07 | 深圳市国赛生物技术有限公司 | Reagent disk |
| CN103472242A (en) * | 2013-10-14 | 2013-12-25 | 中国科学院苏州生物医学工程技术研究所 | Kit conveying device used for full-automatic chemiluminescence immunoassay instrument |
Non-Patent Citations (1)
| Title |
|---|
| 中国轴承工业协会统编: "《滚动轴承基础知识》", 31 August 2006 * |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018032719A1 (en) * | 2016-08-17 | 2018-02-22 | 江苏英诺华医疗技术有限公司 | Fully-automatic biochemical analyzer with non-contact pneumatic mixing device, and method of analysis |
| US11255846B2 (en) | 2017-03-01 | 2022-02-22 | Leadway (Hk) Limited | Reagent mixing and conveying device and reagent mixing method |
| CN108201837A (en) * | 2018-03-19 | 2018-06-26 | 杨雪锋 | A kind of medical tubes automatic mixing device |
| CN110554181A (en) * | 2018-05-30 | 2019-12-10 | 深圳市帝迈生物技术有限公司 | Kit and reagent dish device |
| CN108872078B (en) * | 2018-06-29 | 2020-11-24 | 广州市进德生物科技有限公司 | Full-automatic chemiluminescence analyzer |
| CN108872078A (en) * | 2018-06-29 | 2018-11-23 | 广州市进德生物科技有限公司 | A kind of Full-automatic chemiluminescence analyzer |
| CN109358201A (en) * | 2018-10-16 | 2019-02-19 | 基蛋生物科技股份有限公司 | Full-automatic chemiluminescence immunoassay analysis meter |
| CN109261040A (en) * | 2018-12-04 | 2019-01-25 | 希肯医疗技术（苏州）有限公司 | A kind of poly functional reagent pot |
| WO2020215175A1 (en) * | 2019-04-22 | 2020-10-29 | 深圳迈瑞生物医疗电子股份有限公司 | Magnetic bead reagent uniform mixing apparatus, uniform mixing method, and sample analysis device |
| CN113015910A (en) * | 2019-04-22 | 2021-06-22 | 深圳迈瑞生物医疗电子股份有限公司 | Mixing device and mixing method of magnetic bead reagent and sample analysis equipment |
| CN111000467A (en) * | 2019-12-28 | 2020-04-14 | 黄赛士 | A even stirring adder of misce bene for safety in production |
| CN111514789A (en) * | 2020-04-15 | 2020-08-11 | 林水彬 | Quick dispensing device that medical care used |
| CN111514789B (en) * | 2020-04-15 | 2022-02-18 | 青岛大学附属医院 | Quick dispensing device that medical care used |
| EP4059592A1 (en) * | 2021-03-16 | 2022-09-21 | Swissmeca SA | Sample tube and device and method for dispersing and homogenizing |
| WO2022227724A1 (en) * | 2021-04-28 | 2022-11-03 | 深圳市亚辉龙生物科技股份有限公司 | Reagent mixing and loading device and immunological detection apparatus |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105510613A (en) | Reagent blending conveying device and blending method | |
| US11255846B2 (en) | Reagent mixing and conveying device and reagent mixing method | |
| JP6843826B2 (en) | Chemiluminescence detector and its detection method | |
| CN109142768B (en) | Automatic analyzer and sample analyzing method | |
| CN110133314A (en) | Full-automatic chemiluminescence immunoassay analysis meter | |
| EP1870713B1 (en) | Apparatus for multiple automatic analysis of biosamples, method for autoanalysis, and reaction cuvette | |
| CN202075285U (en) | Minitype rotating disc type full-automatic immunoluminescence analysis system capable of adding sample in whole disc | |
| US11119048B2 (en) | Chemiluminescence detection equipment and its operation method | |
| CN113504380A (en) | Full-automatic chemiluminescence immunoassay analyzer | |
| CN109061210A (en) | A kind of full-automatic illumination chemo-immunity analyzer | |
| CN207866716U (en) | Chemiluminescence detector | |
| CN208721691U (en) | A kind of luminescent chemical immunity analysis instrument | |
| CN203561641U (en) | Chemical luminescence immunity analyzer structure | |
| CN208178045U (en) | A kind of automatic cleaning incubation mixing detection system | |
| CN105388312A (en) | Reagent storing device used for full-automatic analyzer | |
| WO2019183745A1 (en) | Chemiluminescence analyzer and analysis method therefor | |
| CN109975562A (en) | Chemiluminescence detector and its detection method | |
| CN109580596B (en) | Chemiluminescent detector, incubation device and incubation method thereof | |
| CN205333660U (en) | A magnetic particle reagent strorage device for chemiluminescent immunoassay analysis appearance | |
| CN205333666U (en) | Reagent mixing conveyer | |
| CN205333659U (en) | Kit of reagent bottle is equipped with | |
| CN205506850U (en) | A reagent storehouse for external diagnostic equipment | |
| CN205353107U (en) | Full autoanalyzer's reagent strorage device | |
| CN105388311A (en) | Full-automatic chemiluminescence immunoassay instrument | |
| JP2011013148A (en) | Automatic analyzer and magnetic particle moving method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160420 |
|
| RJ01 | Rejection of invention patent application after publication |