The content of the invention
In place of in view of the shortcomings of the prior art, it is an object of the invention to provide a kind of CCN biocontainment laboratories,
Install quick, cheap, pressure difference, humiture can be realized, with the high entrance guard management of degree of safety, it is ensured that experiment safety.
The purpose of the present invention is achieved through the following technical solutions:
A kind of CCN biocontainment laboratories, including door, the first changing rooms, the second changing rooms, laboratory, computer room, air inlet system
System and outlet system of air, the door are entered for CCN biocontainment laboratories, are entered by door in computer room, the computer room, first are more
Between clothing, the second changing rooms, laboratory set gradually, the air inlet system be sequentially communicated including roughing efficiency air filter, medium effeciency filter,
Plenum chamber, centrifugal blower and monoblock type laminar flow hood, the air outlet of the monoblock type laminar flow hood are placed in the interior in laboratory, it is described enter
Wind system is used to continuously convey clean air for laboratory and keeps laboratory to be constantly in positive pressure environment;It is described
Outlet system of air is sequentially communicated including high efficiency particulate air filter and Diffusion of gas stream blowing unit, and the air inlet of the high efficiency particulate air filter is placed in reality
Test the interior of room, the outlet system of air goes out the intake velocity that wind velocity is less than air inlet system;Provided with P2 viruses in the computer room
Laboratory control system, is provided with door lock control system and internal environment monitoring system in the control system of P2 Viral experiments room.
In order to which the present invention is better achieved, pass-through box is provided between the laboratory and the external world.
Further technical scheme is:FFU filter elements are provided with the laboratory.
Further technical scheme is:The door lock control system includes door open button, and the door is provided with enabling
Door lock is controlled, and the door of first changing rooms controls to set on A, the door of second changing rooms provided with the changing rooms door lock opened the door
There is the changing rooms door lock control B of enabling, the door open button controls A, changing rooms door lock with door lock control, changing rooms door lock respectively
B electrical connections are controlled, door open button is used for lock control, changing rooms door lock control A, changing rooms door lock control B on the door and sent out respectively
The control instruction of door.
Currently preferred door lock control system structure technology scheme is:Also include system in the door lock control system
Power supply scram button, system power supply scram button is used for cutting system power supply.
In order to which the various control modes of door open button are better achieved, the door open button controls door.The door open button
Corresponding enabling signal indicator lamp is controlled provided with door lock.Specially:The door open button provided with respectively with door lock control,
Changing rooms door lock control A, the changing rooms door lock control one-to-one enabling signal indicator lamps of B.
The preferred technical scheme of internal environment monitoring system of the present invention is:The internal environment monitoring system includes temperature
Detecting module, ozone concentration detecting module, humidity detecting module and pressure differential detection module, the temperature sensing module, ozone are dense
Degree detecting module, humidity detecting module and pressure differential detection module are correspondingly arranged at the corresponding detection zone in laboratory respectively;Institute
Stating temperature sensing module is used to detect the temperature value of laboratory internal environment and the temperature value detected is transferred into inside in time
Environmental monitoring system;The ozone concentration detecting module is used for the ozone concentration for detecting laboratory internal environment and in time will detection
To ozone concentration be transferred to internal environment monitoring system;The humidity detecting module is used to detect the wet of laboratory internal environment
The humidity value detected is simultaneously transferred to internal environment monitoring system by angle value in time;The pressure differential detection module, which is used to detect, tests
The differential pressure conditions detected are simultaneously transferred to internal environment monitoring system by the differential pressure conditions of chamber interior environment in time.
Preferably, lamp light control system is additionally provided with the P2 Viral experiments room control system, first changing rooms,
Second changing rooms, laboratory, light units, the lamp light control system and each light units electricity are respectively provided with inside computer room
Connection, the lamp light control system is used to control the light units in the first changing rooms, the second changing rooms, laboratory, computer room to open
Open and close.
Preferably, door, the first changing rooms, the second changing rooms, laboratory, machine in the CCN biocontainment laboratories
The equal stainless steel in room or plastic-spraying galvanized steel plain sheet are fabricated by.
The present invention compared with the prior art, with advantages below and beneficial effect:
(1) present invention installs quick, cheap, can realize pressure difference, humiture, with the high gate inhibition's pipe of degree of safety
Reason, it is ensured that experiment safety.
(2) present invention band HVAC system, being capable of independent operating;Using monolithic construction, install easy;And construction period
Short, small investment, simple installation, operating cost is low.The present invention improves cleaniliness classs easily, and autgmentability is strong, and recycling valency
Value is high;And conveniently moving, install it is quick, cheap.The skeleton of the present invention uses modularization section aluminum frame, intensity pole
Height, but also using micro computer control;Also carry ozone/VHP sterilizing functions, pressure difference, humiture, entrance guard management, system monitoring.
The present invention has the functions such as fault alarm, efficient D0P leak detections, and function is very complete, and one-stop cleaning system solution meets
The requirement of CGMP certifications.
Embodiment
As shown in Fig. 1~Fig. 6, a kind of CCN biocontainment laboratories, including door 1, the first changing rooms 2, the second changing rooms 3,
Laboratory 5, computer room 6, air inlet system and outlet system of air, door 1 are entered for CCN biocontainment laboratories, enter computer room by door 1
In 6, computer room 6, the first changing rooms 2, the second changing rooms 3, laboratory 5 are set gradually, and air inlet system is sequentially communicated including just imitating
Filter 7, medium effeciency filter 8, centrifugal blower 10, plenum chamber 11 and monoblock type laminar flow hood 12, the air outlet of monoblock type laminar flow hood 12
The interior in laboratory 5 is placed in, air inlet system is used to continuously convey the air of cleaning for laboratory 5 and keeps laboratory
5 are constantly in positive pressure environment.Outlet system of air is sequentially communicated including high efficiency particulate air filter 13 and Diffusion of gas stream blowing unit 14, efficient mistake
The air inlet of filter 13 is placed in the interior in laboratory 5, and outlet system of air goes out the intake velocity that wind velocity is less than air inlet system.Computer room
P2 Viral experiments room control system 61 is provided with 6, the He of door lock control system 62 is provided with control system 61 in P2 Viral experiments room
Internal environment monitoring system 64.Door 1 of the present invention, the first changing rooms 2, the second changing rooms 3, laboratory 5, the profile structure of computer room 6
Using the aluminium alloy extrusions researched and developed meticulously, door 1, the first changing rooms 2, the second changing rooms 3, laboratory 5, computer room 6 etc. are used as module
Framework, it is ensured that the overall lines linearity requirement after module strength and installation.The integrated conventional keel knot of the section bar
Structure is easy to complete buckle.The integrated drift angle of the section bar, ditch circular arc, are easily installed and lay PVC epoxies ground.Module is easy to connect
Fast.Outward appearance and use requirement are met using overall plastic-spraying after module connection.Door 1 of the present invention, the first changing rooms 2, second are changed one's clothes
Between 3 buckle structure use building enclosure, produced using the keel buckle of industry universal, and be by research improvement exploitation
100 type hollow gypsum purification plates.There is the buckle structure of the 100 type hollow gypsum purification plate the high not dust suction of cleanliness factor, sound insulation to protect
Temperature, the fire prevention characteristics such as A grades.
As shown in Fig. 2 being provided with pass-through box 4 between the laboratory 5 and the external world, tester can be realized by pass-through box 4
The simple operations such as tool transmission.
According to one embodiment of present invention, FFU filter elements 9 are provided with laboratory 5, FFU filter elements 9 can be to reality
Test room 5 and carry out purification run.
As shown in figure 4, door lock control system 62 includes door open button 621, door 1 is provided with the door lock control 15 opened the door, the
The door of one changing rooms 2 is provided with the changing rooms door lock control A21 opened the door, and the door of the second changing rooms 3 is provided with the changing rooms opened the door
Door lock controls B31, and door open button 621 is electric with door lock control 15, changing rooms door lock control A21, changing rooms door lock control B31 respectively
Connection, door open button 621 is used for lock control 15, changing rooms door lock control A21, changing rooms door lock control B31 on the door and sent respectively
The control instruction of enabling, door lock control 15, changing rooms door lock control A21, changing rooms door lock control B31 respond the control and referred to respectively
Make and open corresponding door lock;Changing rooms door lock controls A21 and the control B31 interlockings of changing rooms door lock.
According to one embodiment of present invention, also include system power supply scram button 623 in door lock control system 62, be
Power supply scram button 623 of uniting is used for cutting system power supply.
The door opening state of each door lock control is checked for the ease of people, the door open button 621 controls door 1.Enabling is pressed
Button 621 is provided with to open the door correspondingly with door lock control 15, changing rooms door lock control A21, changing rooms door lock control B31 respectively
Signal lamp 624.
As shown in fig. 6, internal environment monitoring system 64 include temperature sensing module 641, ozone concentration detecting module 642,
Humidity detecting module 643 and pressure differential detection module 644, temperature sensing module 641, ozone concentration detecting module 642, humidity detection
Module 643 and pressure differential detection module 644 are correspondingly arranged at the corresponding detection zone in laboratory 5 respectively.Temperature sensing module 641
For detecting the temperature value of the internal environment of laboratory 5 and the temperature value detected being transferred into internal environment monitoring system in time
64.The present invention coordinates constant temperature and humidity machine there is provided the required air quantity of the present invention, cold, can reach clean requirement.The behaviour of the present invention
Make platform using hundred grades of laminar flow bench, carry out experimental implementation.Ozone concentration detecting module 642 is used to detect the inner loop of laboratory 5
The ozone concentration detected is simultaneously transferred to internal environment monitoring system 64 by the ozone concentration in border in time.Humidity detecting module 643
For detecting the humidity value of the internal environment of laboratory 5 and the humidity value detected being transferred into internal environment monitoring system in time
64.Pressure differential detection module 644 is used for the differential pressure conditions for detecting the internal environment of laboratory 5 and in time passes the differential pressure conditions detected
It is defeated by internal environment monitoring system 64.The above-mentioned functions module of the present invention can be applied in combination, when being applied in combination, by multiple work(
Energy module access air-conditioning system, completes unified air-supply pressure regulation poor, it is ensured that experimental situation cleanliness factor.Can also be by multiple functional modules
The unified connection host computer of control system, carries out overall supervision, real-time monitoring system running situation.If necessary, it can close, open
Single or multiple connected functional modules, carry out partial operation.It can be adjusted by technological requirement module room-size and layout.
As shown in figure 5, lamp light control system 63 is additionally provided with P2 Viral experiments room control system 61, the first changing rooms 2,
Two changing rooms 3, laboratory 5, light units 631, lamp light control system 63 and each light units are respectively provided with inside computer room 6
631 electrical connections, lamp light control system 63 is used to control the light in the first changing rooms 2, the second changing rooms 3, laboratory 5, computer room 6
Equipment 631 is opened and closed.
According to one embodiment of present invention, in CCN biocontainment laboratories door 1, the first changing rooms 2, second are changed one's clothes
Between 3, laboratory 5, the equal stainless steel of computer room 6 or plastic-spraying galvanized steel plain sheet be fabricated by.
Concrete condition is implemented in the design of the present invention:
1st, condition of work:
2nd, structural parameters:
1., workspace temperature:18-26 DEG C, illumination:>=300Lux,
Relative humidity:35-65%RH, noise:≤65dB.
2., workspace cleanliness factor:Local laminar flow, ten thousand grades.
3., workspace is averagely blown wind speed:>=0.36m/s,
Workspace return air inlet wind speed:≤1.5m/s
4., circulated air and pressure difference maintain wind air quantity, can be set according to actual conditions.It is basic that the present invention possesses
Function
● the product is entered interlocking and the identity validation of a few fan doors in laboratory by independent gate control system controllers.
● door-opening mode is determined by technique, is swiped the card respectively, fingerprint recognition, light-sensitive system are chosen to install.
● by the control system being integrated into gate inhibition's display operator control panel, the constant temperature and humidity machine of configuration is controlled, it is whole to ensure
The environment of module reaches requirement of experiment.
● during experiment, previously according to technological requirement regulation experiment institute's chilling requirement and air quantity.
● the personnel in all turnover laboratories have to comply with defined purification route and program, must not change privately;All
Article will by regulation from pass-through box pass in and out laboratory.
● illuminating lamp is normally opened during use, it is ensured that illumination requirement in laboratory.
● being provided with scram button, there is provided in emergency circumstances quickly open the clean gas-tight door of all interlockings.
● there are enough memory space putting on article with convenient use.Also have at laboratory working area for being used for a long time
Memory space.
● Biohazard Safety Equipment is equipped with laboratory.
● set cleaning facility, hand basin:Stainless steel, includes induction tap, automatic hand dryer
● there are reliable supply of electric power and emergency lighting.
● purifying door:Band observation window, door closer.
● efficient air distributor:Stainless steel punch forming.
● air-supply unit:Include fresh wind port, fresh air return air mixing section, air supply section, flow equalization section (maintenance section), it is middle effect section, go out
Wind section, muffler section.
● exhaust fan unit:There is high efficiency particulate air filter filtering outlet.
● operating desk:Stainless steel makes.
The operating method of the present invention is as follows:
The course of work of CCN biocontainment laboratories is completed by automatic control system cooperative mechanical formula differential pressure indicator.It is all
Automatic control process by DDC purification air-conditionings thermostatic constant wet control system (Siemens PLC, PID proportional integral derivative) controller
Complete.All control operations are all carried out by liquid crystal touch screen.Color liquid crystal touch screen removes displays temperature, humidity, ozone
Or outside the running parameter such as the online concentration of VHP, alarm, it is also responsible for the setting operation of all kinds of parameters.Touch-screen screen display and operation
Multipage is divided to show, menu in Chinese guiding is respectively:
The runnable interface of the present invention can be with Display on the same screen Current Temperatures, humidity, testing button, screen set simultaneously " stop/
Operation " button and clock display.
Its parameter such as following table (table 1):
The automatic control system runnable interface controling parameter of table 1
Parameter title |
Conditions dictate/effect |
Remarks |
1. temperature, humidity |
Temperature humidity |
|
2. ozone/online concentration of VHP |
Ozone/VHP real-time concentrations |
Choose to install on demand |
3. manual tests pattern |
Whether normal test blower fan, disinfection system, interlocking etc. |
Choose to install on demand |
4. automatic disinfections pattern |
Automatic disinfection |
Choose to install on demand |
5. stoppings/operation |
Startup/stopping test or automatic disinfection pattern |
|
On runnable interface can with arrange parameter (parameter has " temperature, humidity set " respectively, " ozone or VHP sterilizations,
Safe concentration setting ", " alarm setting " three interfaces).
The automatic control system major function of CCN biocontainment laboratories is as follows:
1., epidemic disaster is shown
Show real time humiture in air lock chamber's chamber body.
2., ozone/VHP concentration on-line monitoring, control
Ozone/VHP concentration on-line monitoring, control, can set sterilizing concentration and safe concentration and attach delay function.
3., warning function
The system has perfect warning function.
Mainly have:Air-valve alarm, constant temperature and humidity machine alarm, gate inhibition's alarm, system alarm.
When any one or more warning data over run, corresponding touch-screen warning function glittering (red) simultaneously sends alarm
Sound, until failture evacuation.
4., sudden-stop function
System is provided in emergency circumstances, quickly opens all functions of mutually locking a door.
The installation operation of CCN biocontainment laboratories is as follows:
1) doorframe is assembled with wall, using mode connects for screw, and connecting portion is doorframe outer stiffening plate and wallboard keel.
2) door-plate is hinged with doorframe, easy installation and removal.
3) aluminium alloy extrusions, is used as module frame;Integrated conventional keel structure is easy to complete buckle.The integrated top of the section bar
Angle, ditch circular arc, are easily installed and lay PVC epoxies ground.
The present invention is after product testing, between the function such as its entrance guard management, system monitoring, fault alarm, efficient D0P leak detections
It is complete, one-stop cleaning system solution.And meet the requirement of CGMP certifications, its performance meets design and relevant criterion rule
Model requirement.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
Any modifications, equivalent substitutions and improvements made within refreshing and principle etc., should be included in the scope of the protection.