CN110645665A - Pharmaceutical system and control method of A-level environment in pharmaceutical system - Google Patents
Pharmaceutical system and control method of A-level environment in pharmaceutical system Download PDFInfo
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- CN110645665A CN110645665A CN201810665656.3A CN201810665656A CN110645665A CN 110645665 A CN110645665 A CN 110645665A CN 201810665656 A CN201810665656 A CN 201810665656A CN 110645665 A CN110645665 A CN 110645665A
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F7/00—Ventilation
- F24F7/04—Ventilation with ducting systems, e.g. by double walls; with natural circulation
- F24F7/06—Ventilation with ducting systems, e.g. by double walls; with natural circulation with forced air circulation, e.g. by fan positioning of a ventilator in or against a conduit
- F24F7/08—Ventilation with ducting systems, e.g. by double walls; with natural circulation with forced air circulation, e.g. by fan positioning of a ventilator in or against a conduit with separate ducts for supplied and exhausted air with provisions for reversal of the input and output systems
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F11/00—Control or safety arrangements
- F24F11/30—Control or safety arrangements for purposes related to the operation of the system, e.g. for safety or monitoring
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F11/00—Control or safety arrangements
- F24F11/70—Control systems characterised by their outputs; Constructional details thereof
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F11/00—Control or safety arrangements
- F24F11/70—Control systems characterised by their outputs; Constructional details thereof
- F24F11/72—Control systems characterised by their outputs; Constructional details thereof for controlling the supply of treated air, e.g. its pressure
- F24F11/74—Control systems characterised by their outputs; Constructional details thereof for controlling the supply of treated air, e.g. its pressure for controlling air flow rate or air velocity
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F11/00—Control or safety arrangements
- F24F11/89—Arrangement or mounting of control or safety devices
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F13/00—Details common to, or for air-conditioning, air-humidification, ventilation or use of air currents for screening
- F24F13/28—Arrangement or mounting of filters
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F3/00—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
- F24F3/12—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling
- F24F3/16—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by purification, e.g. by filtering; by sterilisation; by ozonisation
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F3/00—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
- F24F3/12—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling
- F24F3/16—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by purification, e.g. by filtering; by sterilisation; by ozonisation
- F24F3/167—Clean rooms, i.e. enclosed spaces in which a uniform flow of filtered air is distributed
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F8/00—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying
- F24F8/10—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by separation, e.g. by filtering
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F8/00—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying
- F24F8/20—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by sterilisation
- F24F8/24—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by sterilisation using sterilising media
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F2110/00—Control inputs relating to air properties
- F24F2110/10—Temperature
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F2110/00—Control inputs relating to air properties
- F24F2110/20—Humidity
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F2110/00—Control inputs relating to air properties
- F24F2110/30—Velocity
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F2110/00—Control inputs relating to air properties
- F24F2110/40—Pressure, e.g. wind pressure
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F2110/00—Control inputs relating to air properties
- F24F2110/50—Air quality properties
- F24F2110/64—Airborne particle content
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/20—Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters
Abstract
The invention discloses a pharmaceutical system and a control method of A-level environment in the pharmaceutical system, wherein the pharmaceutical system comprises: a plurality of cabins which are arranged in an isolated manner; a sterilization transfer window located on one side of the chamber; the air conditioner air inlet system is respectively communicated with the cabins through a plurality of air supply channels so as to filter and guide air in a D-level environment into the cabins; the VHP sterilization system is respectively communicated with the cabins through a plurality of conveying pipelines so as to sterilize the air in the cabins to obtain an A-level environment; the system comprises an online monitoring system and a control system, wherein the online monitoring system comprises a plurality of sensors which are arranged in a plurality of cabins so as to monitor the A-level environment in the cabins; and the air conditioner air outlet system is respectively communicated with the cabins through a plurality of air outlet channels so as to discharge air outwards. The technical scheme of the invention can reduce the cost and improve the production efficiency of the medicine.
Description
Technical Field
The invention relates to the technical field of biological pharmacy, in particular to a pharmacy system and a control method of A-level environment in the pharmacy system.
Background
With the continuous development of biotechnology, biopharmaceutical technology is also continuously developed, and engineers have also designed various pharmaceutical systems. In consideration of the influence of bacteria on the medicine in the pharmaceutical process, the pharmaceutical system must be isolated from the external environment, i.e. the production environment in the pharmaceutical system is a class a environment. The background of the pharmaceutical system is mostly D-level environment, so that higher requirements are provided for the construction standard of pharmaceutical factory buildings; and the materials are transferred from the D level environment to the A level environment and must pass through multi-level isolation and transition areas such as B level environment and C level environment, so that the production efficiency of the medicine is greatly influenced, and the production cost is improved.
In view of the above, there is a need to provide further improvements to the current pharmaceutical systems.
Disclosure of Invention
In order to solve at least one of the above technical problems, the present invention provides a pharmaceutical system.
In order to achieve the purpose, the invention adopts a technical scheme that: providing a pharmaceutical system comprising:
a plurality of cabins which are arranged in an isolated manner;
a sterilization transfer window located on one side of the chamber;
the air conditioner air inlet system is respectively communicated with the cabins through a plurality of air supply channels so as to filter and guide air in a D-level environment into the cabins;
the VHP sterilization system is respectively communicated with the cabins through a plurality of conveying pipelines so as to sterilize the air in the cabins to obtain an A-level environment;
the system comprises an online monitoring system and a control system, wherein the online monitoring system comprises a plurality of sensors which are arranged in a plurality of cabins so as to monitor the A-level environment in the cabins;
and the air conditioner air outlet system is respectively communicated with the cabins through a plurality of air outlet channels so as to discharge air outwards.
The air conditioner air inlet system comprises a first filter, a first centrifugal fan, a second filter and a flow equalizing membrane, wherein the first filter, the first centrifugal fan, the second filter and the flow equalizing membrane are sequentially arranged along the air inlet direction.
The air adjusting and feeding system further comprises an air inlet control valve and a static pressure box, the air inlet control valve is communicated with the static pressure box, the other end of the air inlet control valve is communicated with the first centrifugal fan, and the other end of the static pressure box is communicated with the second filter.
The air conditioner air outlet system comprises an air return pipeline, a third filter and a second centrifugal fan, wherein the air return pipeline, the third filter and the second centrifugal fan are sequentially arranged along the air outlet direction.
The air conditioner air outlet system further comprises an air outlet control valve, and two ends of the air outlet control valve are communicated with the air return pipeline and the third filter respectively.
The air conditioner air outlet system further comprises an air exhaust control valve, and the air exhaust control valve is communicated with the second centrifugal fan.
The on-line monitoring system comprises a temperature sensor, a humidity sensor, an air speed sensor, a pressure difference sensor, a concentration sensor and a dust particle sensor, and is used for collecting temperature, humidity, air speed, pressure difference, concentration of atomized hydrogen peroxide and particle data in the cabin.
The pharmaceutical system further comprises a first control valve, a second control valve and a third control valve, wherein the first control valve is positioned between the cabin and the VHP sterilization system so as to control the entry of the atomized hydrogen peroxide; the second control valve is positioned between the cabin and the VHP sterilization system to control the outflow of the atomized hydrogen peroxide; the third control valve is located at the outlet of the chamber to exhaust the gas.
The pharmaceutical system further comprises an alarm system, and the alarm system is electrically connected with the online monitoring system.
In order to achieve the purpose, the invention adopts another technical scheme that: the control method of the A-level environment in the pharmaceutical system is provided and applied to the pharmaceutical system, and comprises the following steps:
sterilizing the cabins to obtain an A-level environment;
filtering air in a D-level environment and pumping the air into a plurality of cabins;
gas in the pharmaceutical process is discharged;
and monitoring A-level environmental data in the cabins, and controlling an air conditioner air inlet system, a VHP (very high-speed processor) sterilization system and an air conditioner air outlet system according to the monitoring data.
The technical scheme mainly comprises an air conditioner air inlet system, a VHP sterilization system, an air conditioner air outlet system and an online monitoring system, wherein the VHP sterilization system can sterilize air in a cabin to obtain an A-level environment, the air conditioner air inlet system filters and introduces air in a D-level environment, and the air conditioner air outlet system discharges the air in the cabin; the on-line monitoring system can detect the environmental data in the cabin, and can control the VHP sterilization system, the air conditioner air inlet system and the air conditioner air outlet system through the environmental processing, so as to maintain the function of the A-level environment in the cabin and facilitate pharmacy. This scheme simple structure, low in production cost can improve the production efficiency of medicine.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.
FIG. 1 is a block diagram of a pharmaceutical system according to an embodiment of the present invention;
fig. 2 is a block diagram of an air inlet system, a first cabin and an air outlet system of an air conditioner according to an embodiment of the present invention.
The implementation, functional features and advantages of the objects of the present invention will be further explained with reference to the accompanying drawings.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that the description of the invention relating to "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying any relative importance or implicit indication of the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present invention.
Referring to fig. 1 and 2, fig. 1 is a block diagram of a pharmaceutical system according to an embodiment of the present invention;
fig. 2 is a block diagram of an air inlet system, a first cabin and an air outlet system of an air conditioner according to an embodiment of the present invention. In an embodiment of the present invention, the pharmaceutical system includes:
a plurality of cabins which are arranged in an isolated manner;
a sterilization transfer window located on one side of the chamber;
the air conditioner comprises an air conditioner air inlet system 10, wherein the air conditioner air inlet system 10 is respectively communicated with a plurality of cabins through a plurality of air supply channels so as to filter and guide air in a D-level environment into the cabins;
the VHP sterilization system 20 is communicated with the cabins through a plurality of conveying pipelines respectively so as to sterilize the air in the cabins to obtain an A-level environment;
the system comprises an online monitoring system 40, wherein the online monitoring system 40 comprises a plurality of sensors which are arranged in a plurality of cabins so as to monitor the class-A environment in the cabins;
and the air conditioner air outlet system 50 is communicated with the cabins through a plurality of air outlet channels respectively, so as to discharge air outwards.
In this embodiment, the chamber is a closed and isolated space, and the environment of each chamber may be different, so as to meet different requirements of the biopharmaceutical configuration, and the specific chamber includes a first chamber 31, a second chamber 32 and a third chamber 33, which may be configured with three pharmaceutical environments. In order to further increase the risk of cabin cross-contamination, an air conditioning circulation mechanism and a VHP sterilization circulation mechanism may also be provided in each cabin. When the materials enter the cabin, the materials need to enter through the sterilization transfer window, the sterilization transfer window adopts two mechanical gates in an interlocking mode, and the materials entering the inside of the equipment through the sterilization transfer window can be effectively sterilized. The VHP sterilization system 20 includes a hydrogen peroxide generator, a delivery conduit, an outlet, and the like. The air within the chamber may be sterilized to place the chamber in a class a environment. The class a environment can be monitored by the online monitoring system 40 for various environmental data, and a warning signal is issued when at least one of the various environmental data is abnormal. The air-conditioning air inlet system 10 and the air-conditioning air outlet system 50 can be controlled according to actual environmental requirements, so as to ensure the stability of the air pressure and the air speed inside and outside the cabin.
The technical scheme of the invention mainly comprises an air conditioner air inlet system 10, a VHP sterilization system 20, an air conditioner air outlet system 50 and an online monitoring system 40, wherein the VHP sterilization system 20 can sterilize the air in a cabin to obtain an A-level environment, the air conditioner air inlet system 10 filters and introduces the air in a D-level environment, and the air conditioner air outlet system 50 discharges the air in the cabin; the on-line monitoring system 40 can detect the environmental data in the cabin, and can control the VHP sterilization system 20, the air conditioner air inlet system 10 and the air conditioner air outlet system 50 through the environmental processing to maintain the function of the A-level environment in the cabin, thereby facilitating the pharmacy. This scheme simple structure, low in production cost can improve the production efficiency of medicine.
In a specific embodiment, the air conditioner air inlet system 10 includes a first filter 11, a first centrifugal fan 12, a second filter 15, and a flow equalizing membrane 16, where the first filter 11, the first centrifugal fan 12, the second filter 15, and the flow equalizing membrane 16 are sequentially disposed along an air inlet direction. In this embodiment, the first filter 11 is a primary filter for filtering dust or large-particle dust in the air, the second filter 15 is a high efficiency filter for filtering bacteria in the air, and the air in the class D environment is prevented from polluting the air in the class a environment, and the first centrifugal fan 12 can improve the air supply efficiency. Further, the air adjusting and feeding system further comprises an air inlet control valve 13 and a static pressure box 14, the air inlet control valve 13 is communicated with the static pressure box 14, the other end of the air inlet control valve 13 is communicated with the first centrifugal fan 12, and the other end of the static pressure box 14 is communicated with the second filter 15. The equalizing membrane 16 and plenum 14 allow air to equalize into the chamber. The intake control valve 13 may be connected to the on-line monitoring system 40 to open the intake control valve 13 when the on-line monitoring system 40 detects a wind pressure is small.
In a specific embodiment, the air-conditioning outlet system 50 includes a return duct 51, a third filter 53 and a second centrifugal fan 54, and the return duct 51, the third filter 53 and the second centrifugal fan 54 are sequentially disposed along an outlet direction. The third filter 53 is a high efficiency filter to maintain the concentration of particles in the chamber. The second centrifugal fan 54 can improve the air outlet efficiency. The air-conditioning air outlet system 50 is arranged at the bottom of the cabin, and the corresponding air-conditioning air inlet system 10 is arranged at the top of the cabin. Further, the air conditioner air outlet system 50 further includes an air outlet control valve 52, and two ends of the air outlet control valve 52 are respectively communicated with the air return pipeline 51 and the third filter 53; the air-conditioning air outlet system 50 further comprises an air exhaust control valve 55, and the air exhaust control valve 55 is communicated with the second centrifugal fan 54. The air outlet control valve 52 and the air exhaust control valve 55 can be connected to the on-line monitoring system 40, so that when the on-line monitoring system 40 detects that the air pressure is small, the air outlet control valve 52 and the air exhaust control valve 55 are opened.
In a specific embodiment, the online monitoring system 40 includes a temperature sensor, a humidity sensor, a wind speed sensor, a differential pressure sensor, a concentration sensor, and a dust particle sensor, so as to collect temperature, humidity, wind speed, differential pressure, concentration of atomized hydrogen peroxide, and particle data in the cabin. The on-line monitoring system 40 can also collect temperature, humidity, wind speed, pressure difference, concentration of atomized hydrogen peroxide and particle data, can perform preliminary processing on the collected data, and can also be automatically controlled by an external control system to control a corresponding control valve.
In a specific embodiment, the pharmaceutical system further comprises a first control valve 61, a second control valve 62 and a third control valve 63, wherein the first control valve 61 is located between the chamber and the VHP sterilization system 20 to control the entry of the atomized hydrogen peroxide solution; the second control valve 62 is positioned between the cabin and the VHP sterilization system 20 to control the outflow of the atomized hydrogen peroxide; the third control valve 63 is located at the outlet of the chamber to exhaust the gas. In this embodiment, the first control valve 61 is used to control the introduction of the atomized hydrogen peroxide, and the flow of the atomized hydrogen peroxide can be controlled by the second control valve, so as to realize the internal circulation of the atomized hydrogen peroxide. The third control valve 63 is used to control the discharge of the gas inside the chamber, and when the third control valve 63 is opened, the gas inside the chamber can be discharged outside the chamber.
Further, the pharmaceutical system further comprises an alarm system, and the alarm system is electrically connected with the online monitoring system 40. When the environment in the cabin is abnormal, an alarm signal can be output outwards through the alarm system to remind workers to pay attention to the alarm system; on the other hand, the interior environment of the cabin is maintained through an internal regulation mechanism so as to ensure normal operation.
In this embodiment, the method for controlling a level a environment in a pharmaceutical system is applied to a pharmaceutical system, and includes:
sterilizing the cabins to obtain an A-level environment;
filtering air in a D-level environment and pumping the air into a plurality of cabins;
gas in the pharmaceutical process is discharged;
and monitoring A-level environmental data in the cabins, and controlling an air conditioner air inlet system, a VHP (very high-speed processor) sterilization system and an air conditioner air outlet system according to the monitoring data.
In the embodiment, in the actual pharmaceutical process, a VHP sterilization system is required to sterilize a plurality of cabins to obtain a class a environment, and in the process, sterilization may be performed by using sterilization methods such as atomized hydrogen peroxide and ultraviolet rays; air pressure, atomizing hydrogen peroxide solution concentration and particle concentration in the cabin can be controlled through air conditioner air inlet system and air conditioner air-out system, and in the pharmacy process, the environmental parameter in the cabin constantly changes, and the environmental parameter can detect through a plurality of sensors, and when at least some sensor data is unusual, can pass through on-line monitoring system control VHP sterilization system, air conditioner air inlet system and air conditioner air-out system to maintain the A level environment in the cabin. For example, during sterilization, the first control valve and the second control valve are opened simultaneously to realize internal circulation. When the concentration of the atomized hydrogen peroxide in the chamber reaches a set value, the first control valve and the second control valve are closed through the online monitoring system.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention, and all modifications and equivalents of the present invention, which are made by the contents of the present specification and the accompanying drawings, or directly/indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (10)
1. A pharmaceutical system, comprising:
a plurality of cabins which are arranged in an isolated manner;
a sterilization transfer window located on one side of the chamber;
the air conditioner air inlet system is respectively communicated with the cabins through a plurality of air supply channels so as to filter and guide air in a D-level environment into the cabins;
the VHP sterilization system is respectively communicated with the cabins through a plurality of conveying pipelines so as to sterilize the air in the cabins to obtain an A-level environment;
the system comprises an online monitoring system and a control system, wherein the online monitoring system comprises a plurality of sensors which are arranged in a plurality of cabins so as to monitor the A-level environment in the cabins;
and the air conditioner air outlet system is respectively communicated with the cabins through a plurality of air outlet channels so as to discharge air outwards.
2. The pharmaceutical system of claim 1, wherein the air conditioning intake system comprises a first filter, a first centrifugal fan, a second filter, and a flow equalization membrane, and the first filter, the first centrifugal fan, the second filter, and the flow equalization membrane are sequentially disposed along an intake direction.
3. The pharmaceutical system of claim 2, wherein the air adjustment inlet system further comprises an inlet control valve and a static pressure tank, the inlet control valve is in communication with the static pressure tank, the inlet control valve has another end in communication with the first centrifugal fan, and the static pressure tank has another end in communication with the second filter.
4. The pharmaceutical system of claim 1, wherein the air conditioning outlet system comprises an air return duct, a third filter, and a second centrifugal fan, and the air return duct, the third filter, and the second centrifugal fan are sequentially disposed along an outlet direction.
5. The pharmaceutical system of claim 4, wherein the air conditioning outlet system further comprises an outlet control valve, and both ends of the outlet control valve are respectively communicated with the return air duct and the third filter.
6. The pharmaceutical system of claim 5, wherein the air conditioning outlet system further comprises an exhaust control valve, the exhaust control valve in communication with the second centrifugal fan.
7. The pharmaceutical system of claim 1, wherein the online monitoring system comprises a temperature sensor, a humidity sensor, a wind speed sensor, a pressure differential sensor, a concentration sensor, and a dust particle sensor to collect temperature, humidity, wind speed, pressure differential, concentration of atomized hydrogen peroxide, and particle data in the cabin.
8. The pharmaceutical system of claim 7, further comprising a first control valve, a second control valve, and a third control valve, the first control valve positioned between the chamber and the VHP sterilization system to control the ingress of the atomized hydrogen peroxide solution; the second control valve is positioned between the cabin and the VHP sterilization system to control the outflow of the atomized hydrogen peroxide; the third control valve is located at the outlet of the chamber to exhaust the gas.
9. The pharmaceutical system of claim 8, further comprising an alarm system electrically connected to the online monitoring system.
10. A control method of A-level environment in a pharmaceutical system is applied to the pharmaceutical system, and is characterized by comprising the following steps:
sterilizing the cabins to obtain an A-level environment;
filtering air in a D-level environment and pumping the air into a plurality of cabins;
gas in the pharmaceutical process is discharged;
and monitoring A-level environmental data in the cabins, and controlling an air conditioner air inlet system, a VHP (very high-speed processor) sterilization system and an air conditioner air outlet system according to the monitoring data.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810665656.3A CN110645665A (en) | 2018-06-26 | 2018-06-26 | Pharmaceutical system and control method of A-level environment in pharmaceutical system |
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|---|---|---|---|
| CN201810665656.3A CN110645665A (en) | 2018-06-26 | 2018-06-26 | Pharmaceutical system and control method of A-level environment in pharmaceutical system |
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| CN110645665A true CN110645665A (en) | 2020-01-03 |
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| CN201810665656.3A Pending CN110645665A (en) | 2018-06-26 | 2018-06-26 | Pharmaceutical system and control method of A-level environment in pharmaceutical system |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN112742282A (en) * | 2020-12-29 | 2021-05-04 | 青岛市中心医院 | Chemotherapy medicine sterilization allotment equipment |
| CN112742282B (en) * | 2020-12-29 | 2023-05-30 | 青岛市中心医院 | Chemotherapy medicine sterilization allotment equipment |
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