CN105497236A - Ointment for treating animal trauma and preparation method thereof - Google Patents
Ointment for treating animal trauma and preparation method thereof Download PDFInfo
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- CN105497236A CN105497236A CN201610036608.9A CN201610036608A CN105497236A CN 105497236 A CN105497236 A CN 105497236A CN 201610036608 A CN201610036608 A CN 201610036608A CN 105497236 A CN105497236 A CN 105497236A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention relates to an ointment for treating animal trauma. Multiple natural Chinese herbal medicines are adopted as raw materials, wherein cortex phellodendri and flos chrysanthemi indici are used for clearing heat and drying dampness and removing toxin and treating wound; pearls are used for removing toxin and promoting granulation; musk is used for activating blood and dissipating mass and relieving pain and eliminating swelling; radix sophorae flavescentis, fructus kochiae, radix puerariae and fructus cnidii are used for clearing heat and eliminating dampness and dispelling wind and arresting itching; radix angelicae is used for dissipating wind and removing dampness and eliminating swelling and expelling pus; assistant borneol has functions of clearing heat and relieving pain; and the medicines in coordinative compatibility promote each other and together realize the functions of eliminating swelling and relieving pain, stopping bleeding and resolving stasis, suppurating and promoting granulation and promoting wound healing and bring a perfect treatment effect on various ruptures, injuries and inflammations.
Description
Technical field
The invention belongs to ointment technical field, be specifically related to a kind of ointment for the treatment of animal injuries and preparation method thereof.
Background technology
Along with improving constantly of people's living standard, the raising pets such as dog, cat increases gradually, and all kinds of wounds that house pet occurs also are being on the increase.A wound, if processing mode method is improper, inappropriate medication, will cause the infection of wound, and the healing time of wound extends, and even occurs the serious consequences such as disunion, brings misery to house pet and pet owner.
At present, the medicament categories for the house pet such as dog, cat traumatism treatment is a lot, and mostly is Western medicine.Although some has therapeutic effect after using, its curative effect is remarkable not or rehabilitation duration is too slow, delays therapic opportunity.
Summary of the invention
In order to solve the problems referred to above that prior art exists, the invention provides a kind of ointment containing multiple natural Chinese medicine component, eutherapeutic treatment animal injuries and preparation method thereof.
The technical solution adopted in the present invention is:
Treat an ointment for animal injuries, its raw material components comprises:
Cortex Phellodendri, 10-20 weight portion;
Margarita, 15-25 weight portion;
Flos Chrysanthemi Indici, 10-20 weight portion;
Stellera chamaejasme L., 5-15 weight portion;
Moschus, 15-25 weight portion;
Radix Sophorae Flavescentis, 2-8 weight portion;
The Fructus Kochiae, 5-12 weight portion;
Radix Puerariae, 5-12 weight portion;
Fructus Cnidii, 5-12 weight portion;
The Radix Angelicae Dahuricae, 5-12 weight portion;
Borneolum Syntheticum, 5-12 weight portion;
Ethyl hydroxybenzoate, 0.2-0.6 weight portion;
Lanoline, 20-40 weight portion;
Vaseline, 60-100 weight portion.
The raw material components of the ointment of further preferred described treatment animal injuries comprises:
Cortex Phellodendri, 15 weight portions;
Margarita, 20 weight portions;
Flos Chrysanthemi Indici, 15 weight portions;
Stellera chamaejasme L., 10 weight portions;
Moschus, 20 weight portions;
Radix Sophorae Flavescentis, 5 weight portions;
The Fructus Kochiae, 8 weight portions;
Radix Puerariae, 8 weight portions;
Fructus Cnidii, 8 weight portions;
The Radix Angelicae Dahuricae, 8 weight portions;
Borneolum Syntheticum, 8 weight portions;
Ethyl hydroxybenzoate, 0.4 weight portion;
Lanoline, 30 weight portions;
Vaseline, 80 weight portions.
Prepare a method for the ointment of described treatment animal injuries, it comprises the steps:
(1) take Margarita, Moschus, Radix Sophorae Flavescentis, the Fructus Kochiae, Radix Puerariae, Fructus Cnidii and the Radix Angelicae Dahuricae respectively, after difference drying, pulverization process, obtain the fine powder of above-mentioned each raw material, the fine powder of described each raw material is fully mixed, obtains the first compound, stand-by;
(2) take Cortex Phellodendri and Flos Chrysanthemi Indici respectively, after difference drying, pulverization process, obtain Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder, described Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder are fully mixed, obtains the second compound;
(3) add ethanol to described second compound of step (2) and at 40-80 DEG C of reflux, extract, 1-2h, after reclaiming ethanol, obtain extracting solution; Described extracting solution is carried out successively filter, concentrate, obtain the concentrate that relative density is 1.1-1.3g/ml, stand-by;
(4) take Stellera chamaejasme L., after drying, pulverization process, obtain Stellera chamaejasme L. fine powder, add petroleum ether solvent, lixiviate 3-5 days in described Stellera chamaejasme L. fine powder, filtration obtains lixiviating solution, is carried out by described lixiviating solution concentrating obtaining concentrated solution, stand-by;
(5) take ethyl hydroxybenzoate, lanoline and vaseline respectively and fully mix, obtaining the 3rd compound; Described 3rd compound is first heated to 140-160 DEG C, then is cooled to 95-105 DEG C, obtain premix material;
(6) in step (5) described premix material, step (2) described concentrate and step (3) described concentrated solution is added, stirring makes it be cooled to 35-45 DEG C, add described Borneolum Syntheticum more afterwards and fully mix, obtaining the ointment of described treatment animal injuries.
In step (1), the granularity of the fine powder of described each raw material is 110-130 order.
In step (2), the granularity of described cypress fine powder and Flos Chrysanthemi Indici fine powder is 110-130 order.
In step (3), the volumetric concentration of described ethanol is 50-70%.
In step (3), before carrying out described reflux, extract, first described second compound is carried out soak at room temperature 5-15min in described ethanol;
The quality of described second compound is 1:10-1:20g/ml with the ratio of the volume of described ethanol.
In step (4), the granularity of described Stellera chamaejasme L. fine powder is 110-130 order.
In step (4), adopt described petroleum ether solvent to repeat three lixiviate process to described Stellera chamaejasme L. fine powder, be specially:
Petroleum ether solvent is added in described Stellera chamaejasme L. fine powder, lixiviate 3-5 days, filtration obtains the first lixiviating solution and the first filtering residue, petroleum ether solvent is added again afterwards in the first filtering residue, lixiviate 3-5 days, filters and obtains the second lixiviating solution and the second filtering residue, add petroleum ether solvent more afterwards in the second filtering residue, lixiviate 3-5 days, filters and obtains the 3rd lixiviating solution; Described first lixiviating solution, the second lixiviating solution, the 3rd lixiviating solution are carried out concentrated rear merging at 60-80 DEG C respectively, obtains concentrated solution, stand-by;
When carrying out each lixiviate process, the quality of described Stellera chamaejasme L. fine powder or filtering residue is 1:1-1:2g/ml with the ratio of the volume of described petroleum ether solvent.
In step (6), described Borneolum Syntheticum is granularity is 110-130 object fine powder.
For the ease of understanding the present invention, below the raw material in the present invention and drug effect are further elaborated.
Cortex Phellodendri, bitter in the mouth cold in nature, has heat clearing and damp drying, and pathogenic fire purging removes steams, effect of detoxification sore treatment.Be used for the treatment of: damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.
Margarita, sweet in the mouth cold in nature, salty, have tranquilizing mind, yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., heat clearing away pendant expectorant, removing nebula improving eyesight, effect of removing toxic substances and promoting granulation.Be used for the treatment of: palpitation with fear, palpitation with a distress feeling, epilepsy, infantile convulsion is twitched, and dysphoria with smothery sensation is quenched one's thirst, sore throat aphtha, and the raw cataracta of order, skin infection does not close up for a long time.
Flos Chrysanthemi Indici, bitter in the mouth cool in nature, pungent, there is heat-clearing and toxic substances removing, effect of dispelling wind suppressing the hyperactive liver.Be used for the treatment of furuncle, carbuncle, erysipelas, eczema, dermatitis, anemopyretic cold, laryngopharynx swelling and pain, hypertension.
Stellera chamaejasme L., the flat bitter in the mouth of property, pungent, there is removing fluid-retention by purgation, effect of removing mass parasite killing.Be used for the treatment of edema abdominal distention, expectorant carnivorism amasss, trusted subordinate's pain, lump in the abdomen, tuberculosis, scabies.Scabies, tinea are controlled in external, kill fly, maggot.
Moschus, acrid in the mouth warm in nature, has refreshment of having one's ideas straightened out, blood circulation promoting and dispersing pathogen accumulation, effect of alleviating pain and detumescence.Be used for the treatment of calentura and kill dusk, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, blood stasis amenorrhea, lump in the abdomen, trusted subordinate's shoot, traumatic injury, and arthralgia pain is numb, carbuncle malignant boil, sore throat, aphtha, ulcerative gingivitis, glue ear.
Radix Sophorae Flavescentis, bitter in the mouth cold in nature, has heat clearing and damp drying, effect of wind dispelling insecticide.Be used for the treatment of toxic-heat and blood stasis, discharging fresh blood stool, jaundice, leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, mange malignant boil, erosion of vulva pruritus due to damp pathogen, scrofula, scald.External treatment trichomonal vaginitis.
The Fructus Kochiae, bitter in the mouth cold in nature, has clearing away heat-damp and promoting diuresis, effect of dispelling wind for relieving itching.Be used for the treatment of dysuria, stranguria with turbid discharge, leukorrhagia, dysentery, rubella, eczema, scabies, skin pruritus, sore.
Radix Puerariae, the flat sweet in the mouth of property, pungent, there is expelling pathogenic factors from muscles for reducing heat, deliver and examine, promoting the production of body fluid to quench thirst, effect of yang invigorating antidiarrheal.Be used for the treatment of fever caused by exogenous pathogens, rigidity pain on the head and nape, measles goes out smooth from the beginning of, rash, epidemic febrile disease is thirsty, diabetes, has loose bowels, dysentery, hypertension, coronary heart disease.
Fructus Cnidii, acrid in the mouth warm in nature, hardship, have warming the kidney to invigorate YANG, removing dampness and killing parasites, effect of dispelling wind for relieving itching.Be used for the treatment of impotence in male, scrotum pruritus due to damp pathogen, woman's infertility, cold-damp leukorrhagia, pudendal pruritus swells and ache, rheumatic arthralgia, eczema scabies.
The Radix Angelicae Dahuricae, acrid in the mouth warm in nature, has the dehumidifying of loose wind, understand things pain-stopping, effect of detumescence and apocenosis.Be used for the treatment of headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Borneolum Syntheticum, acrid in the mouth cold in nature, hardship, have refreshment of having one's ideas straightened out, effect of clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Beneficial effect of the present invention is:
1, the ointment for the treatment of animal injuries of the present invention, adopt multiple natural Chinese medicinal herb as raw material, Cortex Phellodendri, Flos Chrysanthemi Indici and Stellera chamaejasme L. are in order to heat clearing and damp drying, detoxification sore treatment, Margarita is in order to removing toxic substances and promoting granulation, Moschus is in order to blood circulation promoting and dispersing pathogen accumulation, alleviating pain and detumescence, Radix Sophorae Flavescentis, the Fructus Kochiae, Radix Puerariae and Fructus Cnidii are in order to clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching, the Radix Angelicae Dahuricae dehumidifies in order to loose wind, detumescence and apocenosis, be aided with effect that Borneolum Syntheticum has clearing away heat to alleviate pain, compatibility coordinated by above-mentioned all medicines, mutual gain, jointly play reducing swelling and alleviating pain, hemostasia and dissipation blood stasis, removing the necrotic tissue and promoting granulation, promote effect of wound healing, to various ulceration, various damage, various inflammation all has extraordinary therapeutic effect.
2, the Therapeutic Method of the ointment for the treatment of animal injuries of the present invention, by will with Margarita, Moschus moschiferous is fragrant, Radix Sophorae Flavescentis, the Fructus Kochiae, Radix Puerariae, Fructus Cnidii and the Radix Angelicae Dahuricae obtain the first compound as mixed raw material, again using Cortex Phellodendri and Flos Chrysanthemi Indici as raw material, mix successively, alcohol extraction, filter, concentrate and obtain concentrate, be that raw material is through lixiviate with Stellera chamaejasme L., filter, concentrated obtained concentrated solution, with ethyl hydroxybenzoate, lanoline and vaseline are that raw material obtains premix material, afterwards by described first compound, concentrate, concentrated solution and premix material are carried out fully mixed being incorporated in the process of mixing and are added Borneolum Syntheticum, thus make the effective ingredient of above-mentioned various raw material be able to maximum reservation, drug effect is worked in coordination with performance, prepare ointment and there is reducing swelling and alleviating pain, hemostasia and dissipation blood stasis, removing the necrotic tissue and promoting granulation, promote effect of wound healing, to various ulceration, various damage, various inflammation all has extraordinary therapeutic effect.
Detailed description of the invention
1g is represented with 1 weight portion below in embodiment.
Embodiment 1
The present embodiment provides a kind of ointment for the treatment of animal injuries, and its raw material components comprises:
Cortex Phellodendri, 10 weight portions;
Margarita, 25 weight portions;
Flos Chrysanthemi Indici, 10 weight portions;
Stellera chamaejasme L., 15 weight portions;
Moschus, 15 weight portions;
Radix Sophorae Flavescentis, 8 weight portions;
The Fructus Kochiae, 5 weight portions;
Radix Puerariae, 12 weight portions;
Fructus Cnidii, 5 weight portions;
The Radix Angelicae Dahuricae, 12 weight portions;
Borneolum Syntheticum, 5 weight portions;
Ethyl hydroxybenzoate, 0.6 weight portion;
Lanoline, 20 weight portions;
Vaseline, 100 weight portions.
Further, the preparation method of the ointment of described treatment animal injuries comprises the steps:
(1) Margarita, Moschus, Radix Sophorae Flavescentis, the Fructus Kochiae, Radix Puerariae, Fructus Cnidii and the Radix Angelicae Dahuricae is got according to above-mentioned weight fraction another name, after difference drying, pulverization process, obtain the fine powder that granularity is the above-mentioned each raw material of 110 object, the fine powder of described each raw material is fully mixed, obtain the first compound, stand-by;
(2) take Cortex Phellodendri and Flos Chrysanthemi Indici respectively, after difference drying, pulverization process, obtain granularity and be 110 object Cortex Phellodendri fine powders and Flos Chrysanthemi Indici fine powder, described Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder are fully mixed, obtains the second compound;
(3) add volumetric concentration to described second compound of step (2) be 50% ethanol and at 80 DEG C of reflux, extract, 2h, after reclaiming ethanol, obtain extracting solution; Wherein, the quality of described second compound is 1:10g/ml with the ratio of the volume of described ethanol;
Described extracting solution is carried out successively filter, 65 DEG C concentrate, obtain the concentrate that relative density is 1.1g/ml, stand-by;
(4) Stellera chamaejasme L. is taken, after drying, pulverization process, obtaining granularity is 110 order Stellera chamaejasme L. fine powders, adding petroleum ether solvent and control the quality of described Stellera chamaejasme L. fine powder with the ratio of the volume of described petroleum ether solvent in described Stellera chamaejasme L. fine powder is 1:1g/ml, lixiviate 3 days, filters and obtains lixiviating solution;
Described lixiviating solution is first used anhydrous sodium sulfate drying, then concentrates at 60 DEG C, obtain the oily concentrated solution that pistac has special odor, stand-by;
(5) take ethyl hydroxybenzoate, lanoline and vaseline respectively and fully mix, obtaining the 3rd compound; Described 3rd compound is first heated to 140 DEG C, then is cooled to 95 DEG C, obtain premix material;
(6) in step (5) described premix material, step (2) described concentrate and step (3) described concentrated solution is added, stirring makes it be cooled to 35 DEG C, add granularity afterwards be again 110 object Borneolum Syntheticums and fully mix, obtain the ointment of described treatment animal injuries.
Embodiment 2
The present embodiment provides a kind of ointment for the treatment of animal injuries, and its raw material components comprises:
Cortex Phellodendri, 20 weight portions;
Margarita, 15 weight portions;
Flos Chrysanthemi Indici, 20 weight portions;
Stellera chamaejasme L., 5 weight portions;
Moschus, 25 weight portions;
Radix Sophorae Flavescentis, 2 weight portions;
The Fructus Kochiae, 12 weight portions;
Radix Puerariae, 5 weight portions;
Fructus Cnidii, 12 weight portions;
The Radix Angelicae Dahuricae, 5 weight portions;
Borneolum Syntheticum, 12 weight portions;
Ethyl hydroxybenzoate, 0.2 weight portion;
Lanoline, 40 weight portions;
Vaseline, 60 weight portions.
Further, the preparation method of the ointment of described treatment animal injuries comprises the steps:
(1) Margarita, Moschus, Radix Sophorae Flavescentis, the Fructus Kochiae, Radix Puerariae, Fructus Cnidii and the Radix Angelicae Dahuricae is got according to above-mentioned weight fraction another name, after difference drying, pulverization process, obtain the fine powder that granularity is the above-mentioned each raw material of 130 object, the fine powder of described each raw material is fully mixed, obtain the first compound, stand-by;
(2) take Cortex Phellodendri and Flos Chrysanthemi Indici respectively, after difference drying, pulverization process, obtain granularity and be 130 object Cortex Phellodendri fine powders and Flos Chrysanthemi Indici fine powder, described Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder are fully mixed, obtains the second compound;
(3) add volumetric concentration to described second compound of step (2) be 70% ethanol and at 80 DEG C of reflux, extract, 1h, after reclaiming ethanol, obtain extracting solution; Wherein, the quality of described second compound is 1:20g/ml with the ratio of the volume of described ethanol;
Described extracting solution is carried out successively filter, 70 DEG C concentrate, obtain the concentrate that relative density is 1.3g/ml, stand-by;
(4) Stellera chamaejasme L. is taken, after drying, pulverization process, obtaining granularity is 130 order Stellera chamaejasme L. fine powders, adding petroleum ether solvent and control the quality of described Stellera chamaejasme L. fine powder with the ratio of the volume of described petroleum ether solvent in described Stellera chamaejasme L. fine powder is 1:2g/ml, lixiviate 5 days, filtration obtains the first lixiviating solution and the first filtering residue, petroleum ether solvent is added again afterwards in the first filtering residue, lixiviate 5 days, filtration obtains the second lixiviating solution and the second filtering residue, in the second filtering residue, add petroleum ether solvent more afterwards, lixiviate 5 days, filter and obtain the 3rd lixiviating solution; First lixiviating solution, the second lixiviating solution, the 3rd lixiviating solution are all carried out concentrated rear merging at 73 DEG C respectively, obtains concentrated solution, stand-by;
(5) take ethyl hydroxybenzoate, lanoline and vaseline respectively and fully mix, obtaining the 3rd compound; Described 3rd compound is first heated to 160 DEG C, then is cooled to 105 DEG C, obtain premix material;
(6) in step (5) described premix material, step (2) described concentrate and step (3) described concentrated solution is added, stirring makes it be cooled to 45 DEG C, add granularity afterwards be again 130 object Borneolum Syntheticums and fully mix, obtain the ointment of described treatment animal injuries.
Embodiment 3
The present embodiment provides a kind of ointment for the treatment of animal injuries, and its raw material components comprises:
Cortex Phellodendri, 15 weight portions;
Margarita, 20 weight portions;
Flos Chrysanthemi Indici, 15 weight portions;
Stellera chamaejasme L., 10 weight portions;
Moschus, 20 weight portions;
Radix Sophorae Flavescentis, 5 weight portions;
The Fructus Kochiae, 8 weight portions;
Radix Puerariae, 8 weight portions;
Fructus Cnidii, 8 weight portions;
The Radix Angelicae Dahuricae, 8 weight portions;
Borneolum Syntheticum, 8 weight portions;
Ethyl hydroxybenzoate, 0.4 weight portion;
Lanoline, 30 weight portions;
Vaseline, 80 weight portions.
Further, the preparation method of the ointment of described treatment animal injuries comprises the steps:
(1) Margarita, Moschus, Radix Sophorae Flavescentis, the Fructus Kochiae, Radix Puerariae, Fructus Cnidii and the Radix Angelicae Dahuricae is got according to above-mentioned weight fraction another name, after difference drying, pulverization process, obtain the fine powder that granularity is the above-mentioned each raw material of 120 object, the fine powder of described each raw material is fully mixed, obtain the first compound, stand-by;
(2) take Cortex Phellodendri and Flos Chrysanthemi Indici respectively, after difference drying, pulverization process, obtain granularity and be 120 object Cortex Phellodendri fine powders and Flos Chrysanthemi Indici fine powder, described Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder are fully mixed, obtains the second compound;
(3) add volumetric concentration to described second compound of step (2) be 60% ethanol and at 60 DEG C of reflux, extract, 1.5h, after reclaiming ethanol, obtain extracting solution; Wherein, the quality of described second compound is 1:15g/ml with the ratio of the volume of described ethanol;
Described extracting solution is carried out successively filter, 80 DEG C concentrate, obtain the concentrate that relative density is 1.2g/ml, stand-by;
(4) Stellera chamaejasme L. is taken, after drying, pulverization process, obtaining granularity is 120 order Stellera chamaejasme L. fine powders, adding petroleum ether solvent and control the quality of described Stellera chamaejasme L. fine powder with the ratio of the volume of described petroleum ether solvent in described Stellera chamaejasme L. fine powder is 1:1.5g/ml, lixiviate 4 days, filtration obtains the first lixiviating solution and the first filtering residue, petroleum ether solvent is added again afterwards in the first filtering residue, lixiviate 4 days, filtration obtains the second lixiviating solution and the second filtering residue, in the second filtering residue, add petroleum ether solvent more afterwards, lixiviate 4 days, filter and obtain the 3rd lixiviating solution; First lixiviating solution, the second lixiviating solution, the 3rd lixiviating solution are all carried out concentrated rear merging at 65 DEG C respectively, obtains concentrated solution, stand-by;
(5) take ethyl hydroxybenzoate, lanoline and vaseline respectively and fully mix, obtaining the 3rd compound; Described 3rd compound is first heated to 150 DEG C, then is cooled to 100 DEG C, obtain premix material;
(6) in step (5) described premix material, step (2) described concentrate and step (3) described concentrated solution is added, stirring makes it be cooled to 40 DEG C, add granularity afterwards be again 120 object Borneolum Syntheticums and fully mix, obtain the ointment of described treatment animal injuries.
Embodiment 4
The present embodiment provides a kind of ointment for the treatment of animal injuries, and its raw material components comprises:
Cortex Phellodendri, 12 weight portions;
Margarita, 18 weight portions;
Flos Chrysanthemi Indici, 12 weight portions;
Stellera chamaejasme L., 8 weight portions;
Moschus, 16 weight portions;
Radix Sophorae Flavescentis, 4 weight portions;
The Fructus Kochiae, 7 weight portions;
Radix Puerariae, 7 weight portions;
Fructus Cnidii, 7 weight portions;
The Radix Angelicae Dahuricae, 7 weight portions;
Borneolum Syntheticum, 7 weight portions;
Ethyl hydroxybenzoate, 0.3 weight portion;
Lanoline, 30 weight portions;
Vaseline, 70 weight portions.
Further, the preparation method of the ointment of described treatment animal injuries comprises the steps:
(1) Margarita, Moschus, Radix Sophorae Flavescentis, the Fructus Kochiae, Radix Puerariae, Fructus Cnidii and the Radix Angelicae Dahuricae is got according to above-mentioned weight fraction another name, after difference drying, pulverization process, obtain the fine powder that granularity is the above-mentioned each raw material of 120 object, the fine powder of described each raw material is fully mixed, obtain the first compound, stand-by;
(2) take Cortex Phellodendri and Flos Chrysanthemi Indici respectively, after difference drying, pulverization process, obtain granularity and be 120 object Cortex Phellodendri fine powders and Flos Chrysanthemi Indici fine powder, described Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder are fully mixed, obtains the second compound;
(3) add volumetric concentration to described second compound of step (2) be 60% ethanol and at 60 DEG C of reflux, extract, 1h, after reclaiming ethanol, obtain extracting solution; Wherein, the quality of described second compound is 1:18g/ml with the ratio of the volume of described ethanol;
Described extracting solution is carried out successively filter, 70 DEG C concentrate, obtain the concentrate that relative density is 1.2g/ml, stand-by;
(4) Stellera chamaejasme L. is taken, after drying, pulverization process, obtaining granularity is 120 order Stellera chamaejasme L. fine powders, adding petroleum ether solvent and control the quality of described Stellera chamaejasme L. fine powder with the ratio of the volume of described petroleum ether solvent in described Stellera chamaejasme L. fine powder is 1:1.8g/ml, lixiviate 5 days, filtration obtains the first lixiviating solution and the first filtering residue, petroleum ether solvent is added again afterwards in the first filtering residue, lixiviate 5 days, filtration obtains the second lixiviating solution and the second filtering residue, in the second filtering residue, add petroleum ether solvent more afterwards, lixiviate 5 days, filter and obtain the 3rd lixiviating solution; First lixiviating solution, the second lixiviating solution, the 3rd lixiviating solution are all carried out concentrated rear merging at 80 DEG C respectively, obtains concentrated solution, stand-by;
(5) take ethyl hydroxybenzoate, lanoline and vaseline respectively and fully mix, obtaining the 3rd compound; Described 3rd compound is first heated to 150 DEG C, then is cooled to 100 DEG C, obtain premix material;
(6) in step (5) described premix material, step (2) described concentrate and step (3) described concentrated solution is added, stirring makes it be cooled to 40 DEG C, add granularity afterwards be again 120 object Borneolum Syntheticums and fully mix, obtain the ointment of described treatment animal injuries.
Embodiment 5
The present embodiment provides a kind of ointment for the treatment of animal injuries, and its raw material components comprises:
Cortex Phellodendri, 18 weight portions;
Margarita, 22 weight portions;
Flos Chrysanthemi Indici, 18 weight portions;
Stellera chamaejasme L., 12 weight portions;
Moschus, 7 weight portions;
Radix Sophorae Flavescentis, 7 weight portions;
The Fructus Kochiae, 7 weight portions;
Radix Puerariae, 7 weight portions;
Fructus Cnidii, 7 weight portions;
The Radix Angelicae Dahuricae, 7 weight portions;
Borneolum Syntheticum, 7 weight portions;
Ethyl hydroxybenzoate, 0.5 weight portion;
Lanoline, 35 weight portions;
Vaseline, 90 weight portions.
Further, the preparation method of the ointment of described treatment animal injuries comprises the steps:
(1) Margarita, Moschus, Radix Sophorae Flavescentis, the Fructus Kochiae, Radix Puerariae, Fructus Cnidii and the Radix Angelicae Dahuricae is got according to above-mentioned weight fraction another name, after difference drying, pulverization process, obtain the fine powder that granularity is the above-mentioned each raw material of 120 object, the fine powder of described each raw material is fully mixed, obtain the first compound, stand-by;
(2) take Cortex Phellodendri and Flos Chrysanthemi Indici respectively, after difference drying, pulverization process, obtain granularity and be 120 object Cortex Phellodendri fine powders and Flos Chrysanthemi Indici fine powder, described Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder are fully mixed, obtains the second compound;
(3) add volumetric concentration to described second compound of step (2) be 60% ethanol and at 60 DEG C of reflux, extract, 2h, after reclaiming ethanol, obtain extracting solution; Wherein, the quality of described second compound is 1:12g/ml with the ratio of the volume of described ethanol;
Described extracting solution is carried out successively filter, 65 DEG C concentrate, obtain the concentrate that relative density is 1.2g/ml, stand-by;
(4) Stellera chamaejasme L. is taken, after drying, pulverization process, obtaining granularity is 120 order Stellera chamaejasme L. fine powders, adding petroleum ether solvent and control the quality of described Stellera chamaejasme L. fine powder with the ratio of the volume of described petroleum ether solvent in described Stellera chamaejasme L. fine powder is 1:1.2g/ml, lixiviate 3 days, filtration obtains the first lixiviating solution and the first filtering residue, petroleum ether solvent is added again afterwards in the first filtering residue, lixiviate 3 days, filtration obtains the second lixiviating solution and the second filtering residue, in the second filtering residue, add petroleum ether solvent more afterwards, lixiviate 3 days, filter and obtain the 3rd lixiviating solution; First lixiviating solution, the second lixiviating solution, the 3rd lixiviating solution are all carried out concentrated rear merging at 70 DEG C respectively, obtains concentrated solution, stand-by;
(5) take ethyl hydroxybenzoate, lanoline and vaseline respectively and fully mix, obtaining the 3rd compound; Described 3rd compound is first heated to 150 DEG C, then is cooled to 100 DEG C, obtain premix material;
(6) in step (5) described premix material, step (2) described concentrate and step (3) described concentrated solution is added, stirring makes it be cooled to 40 DEG C, add granularity afterwards be again 120 object Borneolum Syntheticums and fully mix, obtain the ointment of described treatment animal injuries.
The ointment of the treatment animal injuries described in embodiment of the present invention 1-5 is faint yellow fine and smooth emulsifiable paste, has the pungent fragrance of Borneolum Syntheticum; Mastic uniform and smooth, without particulate matter, has suitable vicidity, is easy to coating, melting point about 37 DEG C, limit test of microbe compound Chinese veterinary pharmacopoeia pertinent regulations.In addition, depletion wound cream sample 10g loads in centrifuge tube, with 3000r/min
-1the centrifugal 30min of rotating speed, have no lamination.
Experimental example
The present inventor applies the observation of this unguentum by the house pet having wound to clinical 100 examples, wherein dog class 82 example, cat class 18 example.
Application process: every day 1 time, external, gets appropriate unguentum and embrocates in wound surface.
Efficacy assessment standard:
Cure: clinical symptoms disappears completely, recover example orthobiosis 68.
Effective: clinical symptoms partial disappearance, every sign progressively take a turn for the better 27 example.
Invalid: symptom and sign is not improved 5 examples.Total effective rate 95%.
Typical clinical case:
Small body type Poodle, female, 2 years old, 5kg, body temperature 38.4 DEG C.Medical the previous day to be run over and injure left back thigh by electric motor car, and skin injury (wound is about 6cm) is seriously hemorrhage.Time medical, spirit still can.During diagnosis, observe the Canis familiaris L. Canis familiaris L. mental status, whether motion is normal, whether wound pollutes, and whether wound has foreign body, whether has the situations such as fracture, and clap X sheet and check without fracture situation, belong to hind leg and infect wound, exudate is few, and hair is shaved, iodine tincture disinfection by sick Canis familiaris L. wound portion.With hydrogen peroxide, 0.9% normal saline flushing wound, after thorough debridement, finishing edge of wound, sterilized operation stitching, ointment described in outer painting embodiment 3, wound coating every day, fully recovers and takes out stitches for 5 days afterwards.
Small-sized chihuahua dog, public, 1 years old, 3.2kg, body temperature 38 DEG C.Medical the previous day and other Canis familiaris L.s are had a fist fight, by the head that bites, and 3 place's wounds (being tooth to bite), during diagnosis, observe the Canis familiaris L. Canis familiaris L. mental status, whether motion is normal, whether wound pollutes, and whether wound has foreign body, whether there are the situations such as fracture, clap X sheet and check foreign situation, belong to head infection wound, exudate is few, sick Canis familiaris L. wound shaves hair, iodine tincture disinfection.With hydrogen peroxide, 0.9% normal saline flushing wound, after thorough debridement, finishing edge of wound.Sprinkle golden powder for treating wound in wound, external skin smears ointment described in embodiment 4.Every day changes dressings in time, and after 7 days, wound heals completely.
Persian cat, public, 1 years old, 2.8kg, body temperature 38 DEG C.Medical the previous day and other cats are had a fist fight, by the abdominal part that bites, and 2 place's wounds (being tooth to bite), during diagnosis, observe the cat mental status, whether motion is normal, whether wound pollutes, and whether wound has foreign body, whether there are the situations such as fracture, clap X sheet and check foreign situation, belong to abdominal infection wound, exudate is few, sick cat wound shaves hair, iodine tincture disinfection.With hydrogen peroxide, 0.9% normal saline flushing wound, after thorough debridement, finishing edge of wound.Sprinkle golden powder for treating wound in wound, external skin smears ointment described in embodiment 2.Every day changes dressings in time, and after 7 days, wound heals completely.
The even cat of cloth, female, 2 years old, 3kg, body temperature 38.4 DEG C.Medical the previous day to be run over and injure left back pawl by motorcycle, and skin injury (wound is about 4cm) is seriously hemorrhage.Time medical, spirit still can.During diagnosis, observe the cat mental status, whether motion is normal, whether wound pollutes, and whether wound has foreign body, whether has the situations such as fracture, and clap X sheet and check without fracture situation, belong to hind leg and infect wound, exudate is few, and hair is shaved, iodine tincture disinfection by sick Canis familiaris L. wound portion.With hydrogen peroxide, 0.9% normal saline flushing wound, after thorough debridement, finishing edge of wound, sterilized operation stitching, ointment described in outer painting embodiment 5, wound coating every day, fully recovers and takes out stitches for 5 days afterwards.
The present invention is not limited to above-mentioned preferred forms; anyone can draw other various forms of products under enlightenment of the present invention; no matter but any change is done in its shape or structure; every have identical with the application or akin technical scheme, all drops within protection scope of the present invention.
Claims (10)
1. treat an ointment for animal injuries, it is characterized in that, raw material components comprises:
Cortex Phellodendri, 10-20 weight portion;
Margarita, 15-25 weight portion;
Flos Chrysanthemi Indici, 10-20 weight portion;
Stellera chamaejasme L., 5-15 weight portion;
Moschus, 15-25 weight portion;
Radix Sophorae Flavescentis, 2-8 weight portion;
The Fructus Kochiae, 5-12 weight portion;
Radix Puerariae, 5-12 weight portion;
Fructus Cnidii, 5-12 weight portion;
The Radix Angelicae Dahuricae, 5-12 weight portion;
Borneolum Syntheticum, 5-12 weight portion.
2. the ointment for the treatment of animal injuries according to claim 1, it is characterized in that, raw material components comprises:
Cortex Phellodendri, 15 weight portions;
Margarita, 20 weight portions;
Flos Chrysanthemi Indici, 15 weight portions;
Stellera chamaejasme L., 10 weight portions;
Moschus, 20 weight portions;
Radix Sophorae Flavescentis, 5 weight portions;
The Fructus Kochiae, 8 weight portions;
Radix Puerariae, 8 weight portions;
Fructus Cnidii, 8 weight portions;
The Radix Angelicae Dahuricae, 8 weight portions;
Borneolum Syntheticum, 8 weight portions.
3. prepare a method for the ointment of the treatment animal injuries described in claim 1 or 2, it is characterized in that, comprise the steps:
(1) take Margarita, Moschus, Radix Sophorae Flavescentis, the Fructus Kochiae, Radix Puerariae, Fructus Cnidii and the Radix Angelicae Dahuricae respectively, after difference drying, pulverization process, obtain the fine powder of above-mentioned each raw material, the fine powder of described each raw material is fully mixed, obtains the first compound, stand-by;
(2) take Cortex Phellodendri and Flos Chrysanthemi Indici respectively, after difference drying, pulverization process, obtain Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder, described Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder are fully mixed, obtains the second compound;
(3) add ethanol to described second compound of step (2) and at 40-80 DEG C of reflux, extract, 1-2h, after reclaiming ethanol, obtain extracting solution; Described extracting solution is carried out successively filter, concentrate, obtain the concentrate that relative density is 1.1-1.3g/ml, stand-by;
(4) take Stellera chamaejasme L., after drying, pulverization process, obtain Stellera chamaejasme L. fine powder, add petroleum ether solvent, lixiviate 3-5 days in described Stellera chamaejasme L. fine powder, filtration obtains lixiviating solution, is carried out by described lixiviating solution concentrating obtaining concentrated solution, stand-by;
(5) take ethyl hydroxybenzoate, lanoline and vaseline respectively and fully mix, obtaining the 3rd compound; Described 3rd compound is first heated to 140-160 DEG C, then is cooled to 95-105 DEG C, obtain premix material;
(6) in step (5) described premix material, step (2) described concentrate and step (3) described concentrated solution is added, stirring makes it be cooled to 35-45 DEG C, add described Borneolum Syntheticum more afterwards and fully mix, obtaining the ointment of described treatment animal injuries.
4. the preparation method of the ointment for the treatment of animal injuries according to claim 3, is characterized in that, in step (1), the granularity of the fine powder of described each raw material is 110-130 order.
5. the preparation method of the ointment for the treatment of animal injuries according to claim 3, is characterized in that, in step (2), the granularity of described Cortex Phellodendri fine powder and Flos Chrysanthemi Indici fine powder is 110-130 order.
6. the preparation method of the ointment for the treatment of animal injuries according to claim 3, is characterized in that, in step (3), the volumetric concentration of described ethanol is 50-70%.
7. the preparation method of the ointment for the treatment of animal injuries according to claim 3, is characterized in that, in step (3), before carrying out described reflux, extract, first described second compound is carried out soak at room temperature 5-15min in described ethanol;
The quality of described second compound is 1:10-1:20g/ml with the ratio of the volume of described ethanol.
8. the preparation method of the ointment for the treatment of animal injuries according to claim 3, is characterized in that, in step (4), the granularity of described Stellera chamaejasme L. fine powder is 110-130 order.
9. the preparation method of the ointment for the treatment of animal injuries according to claim 3, is characterized in that, in step (4), adopts described petroleum ether solvent to repeat three lixiviate process to described Stellera chamaejasme L. fine powder, is specially:
Petroleum ether solvent is added in described Stellera chamaejasme L. fine powder, lixiviate 3-5 days, filtration obtains the first lixiviating solution and the first filtering residue, petroleum ether solvent is added again afterwards in the first filtering residue, lixiviate 3-5 days, filters and obtains the second lixiviating solution and the second filtering residue, add petroleum ether solvent more afterwards in the second filtering residue, lixiviate 3-5 days, filters and obtains the 3rd lixiviating solution; Described first lixiviating solution, the second lixiviating solution, the 3rd lixiviating solution are carried out concentrated rear merging at 60-80 DEG C respectively, obtains concentrated solution, stand-by;
When carrying out each lixiviate process, the quality of described Stellera chamaejasme L. fine powder or filtering residue is 1:1-1:2g/ml with the ratio of the volume of described petroleum ether solvent.
10. the preparation method of the ointment for the treatment of animal injuries according to claim 3, is characterized in that, in step (6), described Borneolum Syntheticum is granularity is 110-130 object fine powder.
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