CN105497113A - Traditional Chinese medicine composition and application thereof - Google Patents

Traditional Chinese medicine composition and application thereof Download PDF

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Publication number
CN105497113A
CN105497113A CN201610054435.3A CN201610054435A CN105497113A CN 105497113 A CN105497113 A CN 105497113A CN 201610054435 A CN201610054435 A CN 201610054435A CN 105497113 A CN105497113 A CN 105497113A
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chinese medicine
medicine composition
parts
traditional chinese
application
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Chinese (zh)
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张永锋
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition and application thereof. The composition is prepared from frankincense, myrrh, locust tree branches, borneol and elephant hide. The preparation process includes the steps of adding raw material medicines into a medicine tank to be evenly mixed strictly according to proportion, adding sesame oil into the medicine tank so that raw material medicines can be soaked in sesame oil which is higher than the raw material medicines by 1-3 cm, and decocting the medicines for 1 hour with slow fire. The traditional Chinese medicine composition has a remarkable treatment effect on dermatomyositis, skin ulcer, angular cheilitis and wound long-treatment unhealing, is prepared from pure traditional Chinese medicines, and is stable in medicine effect, free of drug resistance, low in cost and suitable for application and popularization.

Description

A kind of Chinese medicine composition and application thereof
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine composition and application thereof.
Background technology
Integumentary system is the first system of defense of the mankind, along with the development of society, the life stress of modern is increasing, the extraneous factor such as atmospheric pollution is more and more serious in addition, people are in sub-health state for a long time, and this makes human body Shou Dao defence line---and integumentary system very easily occurs dry and cracked and suffers bacteriological infection; Folliculitis (being commonly called as fiery pimple), skin ulcer, angular cheilitis (being commonly called as angular chilitis) are modal skin condition of illness, and its sickness rate is high, easily recurs, and has a strong impact on the daily life of patient.Medicine in the market mainly adopts antibiotic to carry out anti-inflammation and sterilization, but the therapeutic effect of these medicines is poor, and the cycle is long, and easily produces drug resistance.
Summary of the invention
The technical problem to be solved in the present invention is, not enough for prior art, a kind of Chinese medicine composition is provided, its can rapid healing to folliculitis, skin ulcer and angular cheilitis, drug resistance can not be produced to virus and body, and this Chinese drug-treated group can promote wound healing.
For reaching above goal of the invention, the present invention adopts following technical scheme:
A kind of Chinese medicine composition, its crude drug comprises:
Olibanum, myrrh, Rumalus sophorae, Borneolum Syntheticum and Corium elephatis.
As preferably, described raw material medicines in portions by weight is as follows:
Olibanum 8 ~ 12;
Myrrh 9 ~ 13;
Rumalus sophorae 4 ~ 6;
Borneolum Syntheticum 4 ~ 6;
Corium elephatis 12 ~ 18;
As preferably, described raw material medicines in portions by weight is as follows:
Olibanum 10;
Myrrh 10;
Rumalus sophorae 5;
Borneolum Syntheticum 5;
Corium elephatis 15.
As preferably, its processing technology of described Chinese medicine composition is as follows:
(1) crude drug added medicinal cupping and mix;
(2) add Oleum sesami in the medicinal cupping in (1), make crude drug be immersed in Oleum sesami; Oleum sesami did not have crude drug 1 ~ 3cm;
(3) slow fire boils 1h.
As preferably, the application of above Chinese medicine composition in treatment folliculitis.
As preferably, the application of above Chinese medicine composition in treatment angular cheilitis.
As preferably, the application of above Chinese medicine composition in treatment skin ulcer.
The invention discloses a kind of Chinese medicine composition, its crude drug comprises Olibanum, myrrh, Rumalus sophorae, Borneolum Syntheticum and Corium elephatis.Wherein, containing actin in Corium elephatis, tropomyosin, hemoglobin, creatine, in triglyceride, palmitic acid content is high, and vitamin content is higher, for granulation promoting, sore, skin infection does not close up for a long time, has protective effect to wound surface; Olibanum, promoting blood circulation and stopping pain, for all pains of trusted subordinate, the contracture of muscle arteries and veins, traumatic injury, sore, carbuncle and painful swelling; Externally used detumescence granulation promoting; Myrrh, eliminating stasis to stop pain, externally used detumescence granulation promoting, swells and ache for traumatic injury congestion, ulcer sore pain, all pains of breast abdomen; External is controlled the open sore part and is not restrained for a long time;
Borneolum Syntheticum, other titles: Borneolum Syntheticum, Borneolum Syntheticum, brain, Borneolum Syntheticum, sheet brain, Borneolum Syntheticum brain, Flos Mume brain, natural Broneolum Syntheticum, old borneol, borneol.Main component: this product is the crystallization obtained from the resin and volatile oil of Borneolum Syntheticum is intimate pure dextro Borneolum Syntheticum.Multiple ter penoids is contained in the resin of Borneolum Syntheticum and volatile oil.Except Borneolum Syntheticum, still containing sesquiterpenes such as Humuleno, beta-elemene, caryophyllene, the triterpenoids such as oleanolic acid, alphitolic acid, asiatic acid, dipterocarpol, dryobalanone, erythrodiol;
Rumalus sophorae, " Bencao Tujing ": " spring adopts twig, forges as grey black, with wipe Chi Qu ?; Cloisonne branch gets drop, to be coated with tinea ", Rumalus sophorae has dissipating blood stasis to stop blooding, heat clearing and damp drying, effect of wind dispelling insecticide.
Through the effort of Chinese medicine family five generation people, by a large amount of clinical verifications, constantly delete, optimizing materials medicine, final discovery, Olibanum, myrrh, Rumalus sophorae, Borneolum Syntheticum and Corium elephatis match, after boiling, finally make paste external application Chinese medicine combination medicine, this Chinese medicine composition is controlled not conform to leather bag inflammation, skin ulcer, angular cheilitis and wound for a long time significant therapeutic effect;
By Olibanum, myrrh, Rumalus sophorae, Borneolum Syntheticum and Corium elephatis, be solvent with Oleum sesami, boil; Oleum sesami and Oleum sesami, on the one hand as solvent, effective ingredient in crude drug can perfectly combine by Oleum sesami, the boiling point of Oleum sesami own is between 150-180, its boiling point boils the solvent (water) of Chinese Herbs Medicines far above tradition, at high temperature raw material the effective elements of the medicine is endured out, and Oleum sesami boiling point is high, and ingredient can be avoided to volatilize along with steam; The on the other hand sweet in the mouth of Oleum sesami, cool own, has effect of loosening bowel to relieve constipation, removing toxic substances and promoting granulation.Record according in Compendium of Material Medica: " have moisturize, detoxify, pain relieving, detumescence merit." " not Lu " say: " sharp large intestine, afterbirth does not fall.Survivor's lump of rubbing swells, raw alopecia ", the lecithin in addition in Oleum sesami has skin moistening function, and auxiliary damaged skin recovers, and prevents from staying scar.
The embodiment of the invention discloses a kind of Chinese medicine composition and application thereof.Those skilled in the art can use for reference present disclosure, and suitable improving technique parameter realizes.Special needs to be pointed out is, all similar replacements and change apparent to those skilled in the art, they are all deemed to be included in the present invention.Product of the present invention is described by preferred embodiment, related personnel obviously can not depart from content of the present invention, spirit and scope product as herein described and method are changed or suitably change with combination, realize and apply the technology of the present invention.
In order to understand the present invention further, below in conjunction with embodiment, the present invention is described in detail.
Detailed description of the invention
Embodiment 1
A kind of Chinese medicine composition, it comprises the crude drug of following weight portion:
Olibanum 8g;
Myrrh 9g;
Rumalus sophorae 4g;
Borneolum Syntheticum 4g;
Corium elephatis 12g;
Mixed by above crude drug and add medicinal cupping, in medicinal cupping, adding Oleum sesami, Oleum sesami did not have crude drug 1 ~ 4cm, under slow fire, boil 1h, and elimination medicinal residues obtain paste Chinese medicine composition.
Embodiment 2
A kind of Chinese medicine composition, it comprises the crude drug of following weight portion:
Olibanum 10g;
Myrrh 10g;
Rumalus sophorae 5g;
Borneolum Syntheticum 5g;
Corium elephatis 15g.
Mixed by above crude drug and add medicinal cupping, in medicinal cupping, adding Oleum sesami, Oleum sesami did not have crude drug 1 ~ 4cm, under slow fire, boil 1h, and elimination medicinal residues obtain paste Chinese medicine composition.
Embodiment 3
A kind of Chinese medicine composition, it comprises the crude drug of following weight portion:
Olibanum 12;
Myrrh 13;
Rumalus sophorae 6;
Borneolum Syntheticum 6;
Corium elephatis 18;
Mixed by above crude drug and add medicinal cupping, in medicinal cupping, adding Oleum sesami, Oleum sesami did not have crude drug 1 ~ 4cm, under slow fire, boil 1h, and elimination medicinal residues obtain paste Chinese medicine composition.
Embodiment 4
Respectively Oleum sesami in embodiment 1 ~ 3 is replaced with water, after slow fire boils, by evaporation, medicinal liquid is modulated into paste Chinese medicine composition.
Experimental example
The Chinese medicine ointment adopting above-described embodiment 1 ~ 4 to obtain makes plaster, is affixed on corresponding case patient affected part, all has positive effect.A large amount of clinical cases proves that described in embodiment 2, the therapeutic effect of Chinese medicine composition to patient is better than other embodiment.
Be below model case:
Xinji City, Ma Zhuan township, Li Huiming, collare minister has a fiery pimple, and with swelling pain sense, head rotation is limited.
Use Chinese medicine composition obtained by embodiment 2, after medication 2 times, condition of illness takes a turn for the better, and redness starts to disappear, and fully recovers after medication 3 times.
Ningjin County, four irises and orchids towns, Wang Yujie, emery wheel is damaged, wound infection, disunion, and with suppuration phenomenon.
Use Chinese medicine composition obtained by embodiment 2, medication is after 2 weeks, and wound healing, forms a scab after three months and thoroughly come off and do not stay any cicatrix.
Xinji City, Zhi Qiu town, large car city village, Liu Yabo, forehead director has fiery pimple.
Use the Chinese medicine composition of embodiment 1 indication, fully recover after medication 3 times, and do not stay cicatrix.
Zhangjiakou City, Xiahuayuan District, Guo, suffers from angular cheilitis, and the corners of the mouth ftractures, red and swollen, comes off with scurf, smears Ascorbyl B6 paste several weeks, Relapse rate before seeking medical advice.
Use Chinese medicine composition obtained by embodiment 2, medication 1 week rear corners of the mouth cracking, red and swollen phenomenon disappear completely.
Shijiazhuang City, Zhao, collare minister has fiery pimple, and affected part is with slight ulcer.
Use Chinese medicine composition obtained by embodiment 3, after medication 3 times, disease disappears completely.
In above embodiment, change dressings and be spaced apart 6 ~ 12 hours, interval of changing dressings is determined at the adhesion amount of skin surface according to plaster.All there is not bad reflection in above-mentioned test example, patient medication reflection is good.
Separately, through the checking of a large amount of cases, take water as the treatment cycle that the treatment cycle of this Chinese medicine composition of solvent will be longer than with Oleum sesami the Chinese medicine composition being solvent.
Chinese medicine composition disclosed in this invention, has no side effect, and cost of drugs is cheap, instant effect, is applicable to promote the use of.
Below be only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (7)

1. a Chinese medicine composition, is characterized in that its crude drug is as follows:
Olibanum, myrrh, Rumalus sophorae, Borneolum Syntheticum and Corium elephatis.
2. a kind of Chinese medicine composition according to claim 1, is characterized in that described raw material medicines in portions by weight is as follows:
Olibanum 8 ~ 12 parts;
Myrrh 9 ~ 13 parts;
Rumalus sophorae 4 ~ 6 parts;
Borneolum Syntheticum 4 ~ 6 parts;
Corium elephatis 12 ~ 18 parts.
3. a kind of Chinese medicine composition according to claim 1 and 2, is characterized in that described raw material medicines in portions by weight is as follows:
Olibanum 10 parts;
Myrrh 10 parts;
Rumalus sophorae 5 parts;
Borneolum Syntheticum 5 parts;
Corium elephatis 15 parts.
4. a kind of Chinese medicine composition according to claim 1 and 2, is characterized in that its processing technology is as follows:
Crude drug is added medicinal cupping and mixes;
In the medicinal cupping in (1), add Oleum sesami, make crude drug be immersed in Oleum sesami; Oleum sesami did not have crude drug 1 ~ 3cm;
Slow fire boils 1h.
5. the application of the Chinese medicine composition as described in claim 1 ~ 5 any one in treatment folliculitis.
6. the application of the Chinese medicine composition as described in claim 1 ~ 5 any one in treatment angular cheilitis.
7. the application of the Chinese medicine composition as described in claim 1 ~ 5 any one in treatment skin ulcer.
CN201610054435.3A 2016-01-27 2016-01-27 Traditional Chinese medicine composition and application thereof Pending CN105497113A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114869937A (en) * 2022-06-14 2022-08-09 徐涛 Medicine for treating external ulcer

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101306117A (en) * 2008-05-26 2008-11-19 李永胜 Production of Qufu powder and Shengjizhangpi paste and evodia fruit paste
CN102327419A (en) * 2011-09-22 2012-01-25 辛胜会 External use medicine for treating wound healing
CN102335309A (en) * 2011-09-26 2012-02-01 张树臣 Formula of ointment for treating burns and scalds
CN103520345A (en) * 2013-10-20 2014-01-22 马光元 External medicine for skin ulcer
CN103989772A (en) * 2014-06-03 2014-08-20 孙忠强 Traditional Chinese medicament for treating skin ulcer and reducing scar formation and preparation process thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101306117A (en) * 2008-05-26 2008-11-19 李永胜 Production of Qufu powder and Shengjizhangpi paste and evodia fruit paste
CN102327419A (en) * 2011-09-22 2012-01-25 辛胜会 External use medicine for treating wound healing
CN102335309A (en) * 2011-09-26 2012-02-01 张树臣 Formula of ointment for treating burns and scalds
CN103520345A (en) * 2013-10-20 2014-01-22 马光元 External medicine for skin ulcer
CN103989772A (en) * 2014-06-03 2014-08-20 孙忠强 Traditional Chinese medicament for treating skin ulcer and reducing scar formation and preparation process thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114869937A (en) * 2022-06-14 2022-08-09 徐涛 Medicine for treating external ulcer

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