CN101028365A

CN101028365A - Medicine for treating burn and ambustion and its production

Info

Publication number: CN101028365A
Application number: CN 200710065752
Authority: CN
Inventors: 杨学栋
Original assignee: Individual
Current assignee: Individual
Priority date: 2007-03-27
Filing date: 2007-03-27
Publication date: 2007-09-05
Anticipated expiration: 2027-03-27
Also published as: CN101028365B

Abstract

A medicine for treating burn and scald is prepared proportionally from the mixed liquid prepared from coptis root, scutellaria root and phellodendron bark, solution of calcium hydroxide and rapeseed oil. Its preparing process is also disclosed.

Description

A kind of medicine for the treatment of burn and preparation method thereof

Technical field

The present invention relates to the Chinese medicine medicine technology field, specifically a kind of medicine for the treatment of burn and preparation method thereof.

Background technology

The method of the burn of modern medicine treatment at present is a bandaging strapping for large tracts of land one, after wound surface is carried out debridement, with the absorptive dressing wrapping of wound surface with thick-layer, wound surface is isolated from the outside, and prevents to pollute and blot sepage; The 2nd, the exposure method after the wound surface debridement, utilizes the baking bed that wound surface is dried; Be in addition in wrapping or exposure method,, antiinflammatory antibiotic, augment nutrition to reach therapeutic purposes to the patient infusion fluid infusion.More than the therapy of treatment burn all must can undergo surgery in sterilizing room, and the medical expense costliness.Chinese traditional treatment at present also has a lot of methods, and wherein curative effect has ZHENGHONGHUA YOU and burn cream method etc. preferably, though better therapeutic effect is also arranged, but easy infection in therapeutic process, sometimes treatment time also drags longlyer, stays cicatrix after the recovery from illness, and most of patients has sequela.

Summary of the invention

The purpose of this invention is to provide a kind of infection, rapid obtundent healing, medicine of the treatment burn of preventing from scar and preparation method thereof.

Of the present invention is the medicine of being made by the following weight proportion raw material:

SANHUANG mixed liquor 10～20%, aqua calcis 30～35%, Semen Lactucae sativae oil 50～60%.

Wherein three yellow liquors are that river Rhizoma Coptidis, Radix Scutellariae and Cortex Phellodendri are formulated.

Preparation method:

1, the SANHUANG mixed liquor is produced:

Add SANHUANG spice Rhizoma Coptidis, Radix Scutellariae and Cortex Phellodendri with 100: 5～10 ratio in clear water, three's ratio is a Rhizoma Coptidis: Radix Scutellariae: Cortex Phellodendri=1: 2～3: 2～3, and heated and boiled half an hour then, it is stand-by to remove slag, filter, cool off the aseptic storage in back;

2, aqua calcis is produced:

In cold boiled water, add calcium oxide (being quicklime) with 10: 1～2 ratio, to be cooled and abundant post precipitation, it is stand-by clarifying aqua calcis to separate out storage;

3, the preparation of medicament:

Earlier the SANHUANG mixed liquor is mixed with aqua calcis, again this mixed liquor is added in the Semen Lactucae sativae oil, stir, promptly get milk yellow water oil suspendible shape liquid preparation.

4, get final product package storage (room temperature is preserved down) after employing glass or the above-mentioned medicament of pottery fill, the sterilization.

The present invention is a kind of external-use burn medicament that I researched and developed in nineteen seventies, through updating for many years, and examples up to a hundred are burnt (scalding) hinder the clinical use observation of patient, curative effect is very satisfied, and its actual therapeutic effect surpasses the domestic and international various external-use burn medicines that use at present.

Medicine of the present invention mainly contains following characteristics:

One, analgesic effect is strong.Burn pain is the most violent, and general medicine all is difficult to pain management, and this medicine then has the magical effect of " medicine ends to pain ", only needs 1-5 minute pain to be eased after the use.

Two, strong infection effect is arranged.It is directly to influence one of burn wound healing even murderous major reason that burn wound infects.This medical instrument has stronger anti-inflammation detumescence, removing toxic substances and promoting granulation function, need not make debridement, disinfection to burn wound and handle, and medicinal liquid is directly embrocated in wound surface, can reach the effect that secondary infection appears in sterilization, antiinflammatory, detumescence and prevention wound surface.

Three, the remarkable effect that has elimination edema wound and inhibition body fluid to exosmose.Wound district edema behind the burn is one of outstanding clinical manifestation of burn patient, because blood liquid composition exosmoses in a large number and can cause hypovolemic shock, directly threatens the wounded's life.Traditional treatment to burn wound adopted passive methods such as tissue oven dry more in the past, can't effectively control sepage and prevention secondary infection.After this medicine is applied to wound surface; can directly produce inhibitory action; effectively suppresses sepage and ooze out, and this medicine is a water oiliness medicinal liquid that adhesive force and penetration are stronger; can form one deck protectiveness medicine film immediately at wound surface; and directly act on wound tissue, and reach inhibition body fluid and ooze out, dredge and eliminate edema; guarantee that wound surface does not have infection, promote the good result of wound healing.

Four, can promote skin histology to regenerate rapidly.Can dissolve the eschar that wound surface forms rapidly, activate impaired wound surface skin substrate tissue effectively, promote the wound surface skin histology to regenerate rapidly.In clinical treatment observation, find, use this medicine case wound surface slough incrustation, come off and the skin growth situation all uses traditional therapy much better; Especially need not make skin graft than large-area burns wound surface skin to shallow II °, dark II °, still can reach and promote the regenerated as early as possible promising result of skin histology, this be other external-use burn medicine class can not compare.

Five, preventing from scar behind the burn wound healing.New burn wound promptly uses the treatment of this medicine at the beginning, and general do not have a phenomenon of infection, the wound surface preventing from scar after the healing, and sweat gland and skin texture also recover as before substantially.It is a great problem of traditional treatment burn that cicatrization is arranged after burn wound cures more, maimed because cicatrization causes function limitation, brings lifelong misery to burn patient.And as long as burn wound infects before using this medicine and forms, the wound surface after using the healing of this medicine promptly can residual cicatrix, and general equal the recovery as before of skin colour, texture and function.

Six, curative effect is fast.Use this medicine treatment burn, effect is remarkable, and wound healing is rapid, and healing time uses other burn topical class medicine to shorten more than one times.

Seven, economic and practical, of many uses.The composition of this medicine constitutes simple, and the medicine source is wide, be easy to gather, and production procedure is uncomplicated and with low cost, and development prospect is preferably arranged.Simultaneously, this medicine also has certain therapeutic effect to general wound, red and swollen skin ulcer joint, eczematous dermatitis etc., is a kind of multi-purpose external medicine.

Eight, easy to use, safe.This medicine is coated with the exposure wet treatment outside using, and medicinal liquid directly need only be embrocated in wound surface, keeps the moistening all the time of wound surface, can reach rapid pain relieving, and prophylactic treatment infects, and promotes skin histology to regenerate rapidly, accelerates the promising result of wound healing, has no side effect.Thereby its can yet be regarded as health care medicine of prophylactic treatment burn of hospitalize burn drug of first choice and family's indispensability.

Drug usage of the present invention and consumption: this medicine is a medicine for external use, after fully shaking up during use, directly medicinal liquid is embrocated in wound surface, and consumption is not limit, and can embrocate repeatedly in 1 day, can cure in general 4～9 days.This product is a topical drug, must guard against for oral administration.

Drug therapy of the present invention routine patients' up to a hundred clinical observation result:

This medicine is used for the People's Hospital's surgery burn specific treatment burn and scald patient when districts and cities, under doctor trained in Western medicine Supporting Therapy cooperates, in various degree burn and scald patient has been used this medicine, therapeutic effect is beat all satisfactory, effective percentage reaches 100%, cure rate and do not have the cicatrix rate and also almost reach 100%, and the hospital stays shortens greatly, medical expense reduces significantly, obtains doctor, nurse and patient's consistent favorable comment.

It is as follows now partly to be treated the case briefing operating period:

Example 1: Zhou Xuzhong, the man 1 years old, lives 11 villages, busy side township, Lincang, Yunnan county.When the patient is admitted to hospital, be diagnosed as right side cervical region and upper arm 5% shallow II ° scald, use this medicine to embrocate wound surface after being admitted to hospital immediately, infant pain subtracts greatly, do not had pain to wound surface on the 3rd, do not had and infect, the infant sanity, it is normal that emotion is recovered, to the 6th day, the infant wound surface did not have sepage, nothing infection, the formation of no eschar, and the wound surface epidermis is ruddy, the 8th day scald wound of being admitted to hospital taken a turn for the better and do not hindered, and promptly leaves hospital.

Example 2: the Gao Xiang, the man 2 years old, lives military subarea, Lincang, Yunnan.Infant is because of being admitted to hospital by two buttocks of boiled water scald and both thighs rear lateral portion accidentally, through looking into two buttockss of infant and both thighs rear side one 30 * 40cm, 15 * 30cm size wound surface is arranged respectively, the surface is covered with big vesicle, the maximum is 9 * 10cm, and a large amount of sepages are arranged, partly exfoliation, wound surface swelling, rubescent, sharp ache.Be diagnosed as two buttockss and two big limb 15% shallow II ° scald.Embrocate wound surface with this medicine, cooperate the correction electrolyte and the anti-inflammatory treatment of doctor trained in Western medicine.Pain is obviously alleviated after the medication, infant emotion calmness, and can take food on a small quantity, pain relief on the secondth, wound exudate reduces, and treatment to wound surface on the 4th has not had pain, the sepage pettiness, the surface is partly dry and hard, does not have and infects, redness disappears, and is admitted to hospital the 6th, and the infant state of an illness is clearly better, the wound surface drying, exhausted most wound surface is formed a scab, does not have infection, no cicatrization, and basic the healing left hospital in the 8th day.

Example 3: Wu Shuanhong, man, 22 years old, people from Chongqing.The patient is admitted to hospital because of being scalded by boiled water accidentally, reach right skin of dorsum of foot below the left lower extremity knee joint a large amount of limpid blisters are arranged, the surrounding skin redness, pain is obvious, be diagnosed as: left lower extremity and right instep scald 12% shallow II ° scald, embrocate Wound treating with this medicine, and give infection, correction water salt balance therapy.Behind the treatment Ninth Heaven, to scald the position incrustation and come off, epidermis is ruddy normal, and do not have and infect, no cicatrix, the basic healing left hospital.

Example 4: Yang Guilan, woman, 20 years old, the workman of Lincang Prefecture, Yunnan building constructor.Be admitted to hospital by " carbide " burn face and right side palm accidentally during because of work, be diagnosed as face and frons, palm back, right side shallow II ° burn surface area 4%, after in the treatment palm back blister being broken water outlet, embrocate Wound treating, after the medication and give antiinflammatory etc. and support to handle with this medicine.Wound surface is formed a scab after four days, and do not have and infect, no cicatrix, healing is left hospital.

Example 5: Chen Yueming, man, 42 years old, the workman of Lincang Prefecture, Yunnan building constructor.The people.The patient is admitted to hospital because of being scalded by boiled water accidentally, reach right skin of dorsum of foot below the left lower extremity knee joint a large amount of limpid blisters are arranged, the surrounding skin redness, pain is obvious, is diagnosed as: left lower extremity and right instep scald 12% shallow II ° scald, embrocate Wound treating with this medicine, pain is obviously alleviated after the medication, continuing treatment has not had pain after 5 days, does not have and infects, no sepage, downright bad epidermal tissue comes off, newborn epidermis is ruddy, the treatment Ninth Heaven, and facial eschar all comes off, no cicatrix, epidermis is ruddy normal, and therapeutic effect is splendid, and healing is left hospital.

The specific embodiment

Embodiment 1:

1, the SANHUANG mixed liquor is produced: the ratio with 100: 5 in clear water adds SANHUANG spice Rhizoma Coptidis, Radix Scutellariae and Cortex Phellodendri, three's ratio is a Rhizoma Coptidis: Radix Scutellariae: Cortex Phellodendri=1: 2: 2, heated and boiled half an hour then, it is stand-by to remove slag, filter, cool off the aseptic storage in back;

2, aqua calcis is produced: in cold boiled water, add calcium oxide (being quicklime) with 10: 1 ratio, and to be cooled and abundant post precipitation, it is stand-by clarifying aqua calcis to separate out storage;

3, the preparation of medicament: earlier SANHUANG mixed liquor 10% is mixed with aqua calcis 35%, in the Semen Lactucae sativae oil with this mixed liquor adding 55%, stir again, promptly get milk yellow water oil suspendible shape liquid preparation.

4, get final product package storage after employing glass or the above-mentioned medicament of pottery fill, the sterilization.

Embodiment 2:

1, the SANHUANG mixed liquor is produced: the ratio with 100: 8 in clear water adds SANHUANG spice Rhizoma Coptidis, Radix Scutellariae and Cortex Phellodendri, three's ratio is a Rhizoma Coptidis: Radix Scutellariae: Cortex Phellodendri=1: 2.5: 2.5, heated and boiled half an hour then, it is stand-by to remove slag, filter, cool off the aseptic storage in back;

2, aqua calcis is produced: in cold boiled water, add calcium oxide with 10: 1.5 ratio, and to be cooled and abundant post precipitation, it is stand-by clarifying aqua calcis to separate out storage;

3, the preparation of medicament: earlier SANHUANG mixed liquor 20% is mixed with aqua calcis 30%, in the Semen Lactucae sativae oil with this mixed liquor adding 50%, stir again, promptly get milk yellow water oil suspendible shape liquid preparation.

Embodiment 3:

1, the SANHUANG mixed liquor is produced: the ratio with 100: 10 in clear water adds SANHUANG spice Rhizoma Coptidis, Radix Scutellariae and Cortex Phellodendri, three's ratio is a Rhizoma Coptidis: Radix Scutellariae: Cortex Phellodendri=1: 3: 3, heated and boiled half an hour then, it is stand-by to remove slag, filter, cool off the aseptic storage in back;

2, aqua calcis is produced: in cold boiled water, add calcium oxide with 10: 2 ratio, and to be cooled and abundant post precipitation, it is stand-by clarifying aqua calcis to separate out storage;

3, the preparation of medicament: earlier SANHUANG mixed liquor 12% is mixed with aqua calcis 30%, in the Semen Lactucae sativae oil with this mixed liquor adding 58%, stir again, promptly get milk yellow water oil suspendible shape liquid preparation.

Claims

1, a kind of medicine for the treatment of burn is characterized in that it is the medicine of being made by the following weight proportion raw material: SANHUANG mixed liquor 10～20%, aqua calcis 30～35%, Semen Lactucae sativae oil 50～60%; Wherein three yellow liquors are that river Rhizoma Coptidis, Radix Scutellariae and Cortex Phellodendri are by 1: 2～3: 2～3 mixed liquors that are mixed with.

2, the preparation method of the medicine of treatment burn as claimed in claim 1 is characterized in that carrying out according to the following steps:

1) the SANHUANG mixed liquor is produced:

2) aqua calcis is produced:

In cold boiled water, add calcium oxide with 10: 1～2 ratio, to be cooled and abundant post precipitation, it is stand-by clarifying aqua calcis to separate out storage;

3) preparation of medicament: