CN1593540A - Ointment for treating burns and scalds and its preparation - Google Patents
Ointment for treating burns and scalds and its preparation Download PDFInfo
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- CN1593540A CN1593540A CN 200410024499 CN200410024499A CN1593540A CN 1593540 A CN1593540 A CN 1593540A CN 200410024499 CN200410024499 CN 200410024499 CN 200410024499 A CN200410024499 A CN 200410024499A CN 1593540 A CN1593540 A CN 1593540A
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Abstract
The invention relates to a pharmaceutical composition for treating burn and scald and process for its preparation, wherein the composition is prepared from coptis, corktree bark, rhubarb horsetails, garden burnet root, ragwort, alkanna tinctoria, dahurian angelica root, calamine, gypsum fibrosum preparata, sophora bud, borneol.
Description
Affiliated technical field
The invention belongs to Chinese medicine preparation and preparation method thereof, especially for Chinese medicine preparation for the treatment of burn and scald and preparation method thereof.
Background technology
Burn and scald is common clinically injury, the medicine of treatment burn and scald has a lot, during some drug use to the patient stimulate heavy patient in the early stage pain unbearably Chinese patent application 97105945.4 a kind of burn oil is disclosed, according to applicant's introduction the effect of pain relieving granulation promoting is preferably arranged, but remain in some shortcomings.
Summary of the invention
The technical scheme that the purpose of this invention is to provide a kind of Chinese medicine preparation of novel therapeutic burn and scald, another object of the present invention provide the preparation method of this medicine.
Technical scheme of the present invention is,
Rhizoma Coptidis 8-15 Cortex Phellodendri 8-15 Radix Et Rhizoma Rhei 18-30 Radix Sangusorbae 8-15
Herba Artemisiae Anomalae 8-15 Radix Arnebiae (Radix Lithospermi) 8-15 Radix Angelicae Dahuricae 8-15 Calamina (calcined and quenched) 30-50
Gypsum Fibrosum Preparatum 30-50 Flos Sophorae Immaturus 8-15 Borneolum Syntheticum 1-5
Preferably raw material weight umber ratio is,
Rhizoma Coptidis 10 Cortex Phellodendris 10 Radix Et Rhizoma Rhei 20 Radix Sangusorbaes 10
Herba Artemisiae Anomalae 10 Radix Arnebiae (Radix Lithospermi)s 10 Radixs Angelicae Dahuricae 10 Calamina (calcined and quenched) 40
Gypsum Fibrosum Preparatum 40 Flos Sophorae Immaturus 10 Borneolum Syntheticums 1
The preparation method of medicine is,
A. oil immersion takes by weighing Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Sangusorbae, Herba Artemisiae Anomalae, Radix Arnebiae (Radix Lithospermi), the Radix Angelicae Dahuricae, the Flos Sophorae Immaturus according to weight and immerses in the Oleum sesami of 200-300 weight portion and soaked 8-24 hour,
B. fried, be heated to oily temperature 120-150 ℃ above raw material is exploded to withered and yellow with steady fire, the elimination medicinal residues,
C. mix to receive cream, will be crushed to 80-120 purpose Calamina (calcined and quenched), Gypsum Fibrosum Preparatum powder and put into the cool back of Oleum sesami and add Borneolum Syntheticum and receive cream,
D. pack.
For improving the effect of medicine, crude drug also has,
Galla Chinensis 8-15 Radix Angelicae Sinensis 8-15 Radix Rehmanniae 18-30 Radix Scutellariae 8-15
Fructus Gardeniae 8-15 Olibanum 8-15 Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15 catechu 8-15
Flos Lonicerae 8-15 Radix Glycyrrhizae 8-15 Mirabilitum crystallina 30-50 Corium elephatis 8-15
Halloysitum Rubrum 30-50 Cera Flava 18-30
Preferably prescription is,
Rhizoma Coptidis 10 Cortex Phellodendris 10 Radix Et Rhizoma Rhei 20 Radix Sangusorbaes 10
Herba Artemisiae Anomalae 10 Radix Arnebiae (Radix Lithospermi)s 10 Radixs Angelicae Dahuricae 10 Calamina (calcined and quenched) 40
Gypsum Fibrosum Preparatum 40 Flos Sophorae Immaturus 10 Borneolum Syntheticums 2 Halloysitum Rubrums 40
Mirabilitum crystallina 40 Galla Chinensiss 10 Radix Angelicae Sinensis 10 Radix Rehmanniae 20
Radix Scutellariae 10 Fructus Gardeniaees 10 Olibanums 10 Pseudobulbus Bletillae (Rhizoma Bletillae) 10
Catechu 10 Flos Loniceraes 10 Radix Glycyrrhizaes 10 Corium elephatiss 10
The preparation method of ointment,
A. oil immersion, taking by weighing Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Sangusorbae, Herba Artemisiae Anomalae, Radix Arnebiae (Radix Lithospermi), the Radix Angelicae Dahuricae, the Flos Sophorae Immaturus, Galla Chinensis, Radix Angelicae Sinensis, the Radix Rehmanniae, Radix Scutellariae, Fructus Gardeniae, Olibanum, Pseudobulbus Bletillae (Rhizoma Bletillae), catechu, Flos Lonicerae, Radix Glycyrrhizae according to weight immerses in the Oleum sesami of 400-500 weight portion and soaked 8-24 hour
B. fried, be heated to oily temperature 120-150 ℃ above raw material is exploded to withered and yellow with steady fire, the elimination medicinal residues,
C. mix receipts cream, the Cera Flava of pulverizing 80-120 purpose Calamina (calcined and quenched), Gypsum Fibrosum Preparatum, Mirabilitum crystallina, Halloysitum Rubrum, Corium elephatis powder and 20 weight portions put into the cool back of Oleum sesami add Borneolum Syntheticum receipts cream,
D. pack.
The preparation method of powder,
Take by weighing Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, charred Radix Sanguisorbae, Liu according to the weight portion of determining and post anger, Radix Arnebiae (Radix Lithospermi), the Radix Angelicae Dahuricae, the Flos Sophorae Immaturus, Galla Chinensis, Radix Angelicae Sinensis, the Radix Rehmanniae, Radix Scutellariae, Fructus Gardeniae, Olibanum, Pseudobulbus Bletillae (Rhizoma Bletillae), catechu, Flos Lonicerae, Radix Glycyrrhizae, Calamina (calcined and quenched), Gypsum Fibrosum Preparatum, Mirabilitum crystallina, Halloysitum Rubrum, Corium elephatis, Borneolum Syntheticum, all material medicine pulverize separately are packaged spare to 80-120 order uniform mixing.
The using method of ointment: clean wound surface with normal saline earlier during use, cut off the infective wound surface beancurd sheet gently, have the blister patient to puncture blister with the aseptic syringe needle low level and emit hydrops, ointment is put on the skin be coated with wound surface, diel is put on the skin 3 times-5 times.After wound surface ties pale brown color crust, to put on the skin 1-2 time every day, wound surface is with covering, in order to avoid infect.
Effect: pain relieving, convergence, drying, antiinflammatory, the growth of promotion epithelium granulation.
The using method of powder: during use Calx is put into container and precipitate, get surface clarification page or leaf, Ovum Gallus domesticus album is mixed with the Calx clear liquor, add the medicamental pulverata mediation and evenly be coated with wound surface.
Effect: pain relieving, convergence, drying, antiinflammatory.Best to I, II burn and scald effect.
The property of medicine below in conjunction with each material medicine illustrates its effect in medicine of the present invention,
Galla Chinensis: bitter in the mouth acid, property is flat.External has convergence, the cellulitis eczema, fester suppurate, flowing water does not close up for a long time etc.
Radix Angelicae Sinensis: acrid-sweet flavor, little hardship, warm in nature.Enrich blood, invigorate blood circulation, collateral dredging, the effect of external dissipating blood stasis for subsidence of swelling.
The Radix Rehmanniae: sweet and slightly bitter taste, cold in nature.Mainly contain heat clearing and blood cooling, and can stop blooding, can promote blood coagulation, external can cooling blood and dissolving purpura.
Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, Flos Lonicerae, Fructus Gardeniae Six-element medicine have combined effect, but heat-clearing and toxic substances removing, noxious heat in the blood system smoulder and give birth to skin infection furuncle and phyma poison, antibacterial and anti-inflammation functions is arranged.
Radix Sangusorbae: sour in the mouth, hardship, cold nature.Effect has removing heat from blood, can be used for carbuncle skin infection and burn and scald outward.The energy pain relieving also accelerates healing, promotes new skin growth.
Olibanum: acrid in the mouth, hardship, slightly warm in nature, major function have promoting the circulation of blood, invigorate blood circulation, loose congestion, same meridians.Can therapeutical effect be arranged to traumatic injury stasis and resolving masses alive.External carbuncle wound poison, red and swollen tall and big pain subduing swelling and relieving pain.
Herba Artemisiae Anomalae: bitter, warm in nature.Blood system is specially gone in main effect, and the swollen analgesic therapy hemostatic effect of the current stagnation resolvation of temperature can be controlled wound, hemorrhage and burn and scald.
Pseudobulbus Bletillae (Rhizoma Bletillae): bitter in the mouth, property are put down.Astringing to arrest bleeding, muscle-growing and detumescence, closing in are arranged, knife injury is hemorrhage and burn and scald etc.
Radix Arnebiae (Radix Lithospermi): salty in the mouth is sweet, and is cold in nature.Interaction energy leads to nine orifices, and diuretic disappears swollen.Removing heat from blood arranged, invigorate blood circulation, heat-clearing and toxic substances removing, the carbuncle skin infection.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.Diffusing phoenix, dehumidifying, sensible, evacuation of pus, pain relieving five functional are arranged.The effect that external has sterilization evacuation of pus, granulation promoting to put on flesh, remove the rotten and let fresh grow.The antibacterial of inhibition and antibacterial action are arranged.
The Flos Sophorae Immaturus: nature and flavor hardship, cold are trembled with fear into conscience intestinal four warps, are rich in rutin, protein, enhance metabolism.
Radix Glycyrrhizae: sweet in the mouth, property are put down.Mainly contain heat-clearing and toxic substances removing, the effect of the emergency and the mediation property of medicine.
Catechu: bitter and puckery flavor, cold nature.The moisture absorption heat clearing away is arranged, promoting tissue regeneration and ulcer healing, analgesic therapy hemostasis.
Calamina (calcined and quenched): sweet in the mouth, property are put down.Promoting tissue regeneration and ulcer healing is arranged, and dampness detoxifcation is used for skin ulcer and bursts and do not close up for a long time.
Gypsum Fibrosum Preparatum: acrid-sweet flavor, cold in nature.Heat clearing away, damp eliminating are arranged, the itching relieving effect.
Halloysitum Rubrum: sweet in the mouth, sour and astringent, warm in nature.Have astringent or styptic treatment for spontaneous sweatingly, removing dampness, is used for the skin ulcer cellulitis outward and does not close up for a long time hemostasis, leukorrhagia stopping.
Mirabilitum crystallina: acrid in the mouth is salty, property Great Cold.Function has clearing away heat-fire, removing heat from blood.External can be controlled burn and scald.
Corium elephatis: bitter in the mouth, property is flat.Mainly contain the function of promoting tissue regeneration and wound healing.
Borneolum Syntheticum: acrid in the mouth hardship, cold nature.Act on fragrant key and be apt to away, nowhere less than, the stagnated fire of loosing, logical all keys are used for various sore swollen toxins outward, reducing swelling and alleviating pain, the person that burst the taking poison and growing muscle due deodorization of can dispelling.
Oleum sesami and Cera Flava: absorb moisture, wound surface is moistened, reduce local excitation, promote fresh epithelial growth.
The present invention forms after further arrangement replenishes according to proved recipe handed down from one's ancestors, medicine of the present invention all has curative effect preferably to I, II, III degree burn and scald, particularly to I, II burn and scald better efficacy, use this medicine do not need in addition with other antibacterials with live special burn ward, medical expense is cheap, is suitable for vast rural area patient and uses.
Observation of curative effect:
Medicine of the present invention basis is a secret prescription handed down in the family from generation to generation, has been applied to for many years clinically, and it is a lot of to treat various burn and scald cases, only nearest some cases curative effect situation is described as follows below:
| The burn and scald degree | Number of patients | The mean treatment time | The healing situation | Remarks |
| I??II | 62 | 5-7 days | The full healing | |
| II III low-grade infection | 20 | 7-15 days | The full healing | |
| II III grade and moderate infection | 18 | 10-20 days | 95％ | Be aided with the antibiotics transfusion |
Case 1, what * *, male, electrogas welding workman by acetylene flame burn arm, mostly are II degree burn in the work, and wherein 40% is the III burn, hinders the back severe infections, cures in 10 days with ointment treatment of the present invention.
Case 2, Liu * *, women, housewife are scalded by boiled water when doing housework accidentally, and scalding area reaches 30% of whole body, cures in 8 days with ointment treatment of the present invention.
The invention has the beneficial effects as follows, medicine of the present invention adopts the multiple appropriate compatibility of medicine that has heat-clearing and toxic substances removing, anti-inflammation and sterilization, analgesic hemostatic, blood circulation promoting and blood stasis dispelling, the taking poison and growing muscle due of dispelling, accelerates wound surface healing, the new skin growth of promotion, each medicine complements each other, use this medicine do not need in addition with other antibacterials with live special burn ward, medical expense is cheap, is suitable for vast rural area patient and uses.
The specific embodiment
The specific embodiment of the present invention is, as shown in the figure:
Embodiment 1,
A. oil immersion takes by weighing Rhizoma Coptidis 50g, Cortex Phellodendri 50g, Radix Et Rhizoma Rhei 100g, Radix Sangusorbae 50g, Herba Artemisiae Anomalae 50g, Radix Arnebiae (Radix Lithospermi) 50g, Radix Angelicae Dahuricae 50g, Flos Sophorae Immaturus 50g and immerses in the Oleum sesami of 1500g and soaked 8-24 hour,
B. fried, with steady fire be heated to oily temperature 120-140 ℃ above raw material is fried to withered and yellow, the elimination medicinal residues,
C. mix to receive cream, will be crushed to 80-120 purpose Calamina (calcined and quenched) 200g, Gypsum Fibrosum Preparatum 200g powder and put into the cool back of Oleum sesami and add Borneolum Syntheticum 5g and receive cream,
D. pack.
Embodiment 2,
A. oil immersion takes by weighing Rhizoma Coptidis 75g, Cortex Phellodendri 50g, Radix Et Rhizoma Rhei 100g, charred Radix Sanguisorbae 75g, Herba Artemisiae Anomalae 50g, Radix Arnebiae (Radix Lithospermi) 50g, Radix Angelicae Dahuricae 50g, Flos Sophorae Immaturus 50g and immerses in the Oleum sesami of 1500g and soaked 12 hours,
B. fried, with steady fire be heated to oily temperature 120-140 ℃ above raw material is fried to withered and yellow, the elimination medicinal residues,
C. mix to receive cream, will be crushed to 80-120 purpose Calamina (calcined and quenched) 250g, Gypsum Fibrosum Preparatum 200g powder and put into the cool back of Oleum sesami and add Borneolum Syntheticum 10g and receive cream,
D. pack.
Embodiment 3,
A. oil immersion, taking by weighing Rhizoma Coptidis 50g, Cortex Phellodendri 50g, Radix Et Rhizoma Rhei 100, Radix Sangusorbae 50g, Herba Artemisiae Anomalae 50g, Radix Arnebiae (Radix Lithospermi) 50g, Radix Angelicae Dahuricae 50g, Flos Sophorae Immaturus 50g, Galla Chinensis 50g, Radix Angelicae Sinensis 50g, Radix Rehmanniae 100g, Radix Scutellariae 50g, Fructus Gardeniae 50g, Olibanum 50g, Pseudobulbus Bletillae (Rhizoma Bletillae) 50g, catechu 50g, Flos Lonicerae 50g, Radix Glycyrrhizae 50g according to weight immerses in the Oleum sesami of 2000g and soaked 8-24 hour
B. fried, with steady fire be heated to oily temperature 120-140 ℃ above raw material is fried to withered and yellow, the elimination medicinal residues,
C. mix and receive cream, the Cera Flava that is crushed to 80-120 purpose Calamina (calcined and quenched) 200g, Gypsum Fibrosum Preparatum 200g, Mirabilitum crystallina 200g, Halloysitum Rubrum 200g, Corium elephatis 50g powder and 100g is put into the cool back adding of Oleum sesami Borneolum Syntheticum 10g receive cream,
D. pack.
Embodiment 4. takes by weighing Rhizoma Coptidis 50g, Cortex Phellodendri 50g, Radix Et Rhizoma Rhei 100, charred Radix Sanguisorbae 50g, Herba Artemisiae Anomalae 50g, Radix Arnebiae (Radix Lithospermi) 50g, Radix Angelicae Dahuricae 50g, Flos Sophorae Immaturus 50g, Galla Chinensis 50g, Radix Angelicae Sinensis 50g, Radix Rehmanniae 100g, Radix Scutellariae 50g, Fructus Gardeniae 50g, Olibanum 50g, Pseudobulbus Bletillae (Rhizoma Bletillae) 50g, catechu 50g, Flos Lonicerae 50g, Radix Glycyrrhizae 50g, Calamina (calcined and quenched) 200g, Gypsum Fibrosum Preparatum 200g, Mirabilitum crystallina 200g, Halloysitum Rubrum 200g, Corium elephatis 50g, Borneolum Syntheticum 10g pulverize separately to 80-120 order uniform mixing makes powder.
Claims (8)
1. medicine for the treatment of burn and scald is characterized in that: the main medicine that obtains according to following preparation method by the raw material of following weight parts ratio,
Rhizoma Coptidis 8-15 Cortex Phellodendri 8-15 Radix Et Rhizoma Rhei 18-30 Radix Sangusorbae 8-15
Herba Artemisiae Anomalae 8-15 Radix Arnebiae (Radix Lithospermi) 8-15 Radix Angelicae Dahuricae 8-15 Calamina (calcined and quenched) 30-50
Gypsum Fibrosum Preparatum 30-50 Flos Sophorae Immaturus 8-15 Borneolum Syntheticum 1-5
2. the described a kind of medicine for the treatment of burn and scald of claim 1, it is characterized in that: wherein each crude drug consumption is,
Rhizoma Coptidis 10 Cortex Phellodendris 10 Radix Et Rhizoma Rhei 20 Radix Sangusorbaes 10
Herba Artemisiae Anomalae 10 Radix Arnebiae (Radix Lithospermi)s 10 Radixs Angelicae Dahuricae 10 forge furnaces sweet 40
Gypsum Fibrosum Preparatum 40 Flos Sophorae Immaturus 10 Borneolum Syntheticums 1
3. claim 1 or 2 described a kind of preparation methoies for the treatment of the medicine of burn and scald is characterized in that:
A. oil immersion takes by weighing Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Sangusorbae, Liu according to weight and posts in the Oleum sesami that anger, Radix Arnebiae (Radix Lithospermi), the Radix Angelicae Dahuricae, the Flos Sophorae Immaturus immerses the 200-300 weight portion and soaked 8-24 hour,
B. fried, be heated to oily temperature 120-150 ℃ above raw material is exploded to withered and yellow with steady fire, the elimination medicinal residues,
C. mix to receive cream, will pulverize 80-120 purpose Calamina (calcined and quenched), the Gypsum Fibrosum Preparatum powder is put into the cool back of Oleum sesami and added Borneolum Syntheticum receipts cream,
D. pack.
4. by the described a kind of medicine for the treatment of burn and scald of claim 1, it is characterized in that: wherein also have crude drug,
Galla Chinensis 8-15 Radix Angelicae Sinensis 8-15 Radix Rehmanniae 18-30 Radix Scutellariae 8-15
Fructus Gardeniae 8-15 Olibanum 8-15 Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15 catechu 8-15
Flos Lonicerae 8-15 Radix Glycyrrhizae 8-15 Mirabilitum crystallina 30-50 Corium elephatis 8-15
Halloysitum Rubrum 30-50 Cera Flava 18-30
5. by the described a kind of medicine for the treatment of burn and scald of claim 4, it is characterized in that: wherein the consumption of each crude drug is,
Rhizoma Coptidis 10 Cortex Phellodendris 10 Radix Et Rhizoma Rhei 20 Radix Sangusorbaes 10
Herba Artemisiae Anomalae 10 Radix Arnebiae (Radix Lithospermi)s 10 Radixs Angelicae Dahuricae 10 Calamina (calcined and quenched) 40
Gypsum Fibrosum Preparatum 40 Flos Sophorae Immaturus 10 Borneolum Syntheticums 2 Halloysitum Rubrums 40
Mirabilitum crystallina 40 Galla Chinensiss 10 Radix Angelicae Sinensis 10 Radix Rehmanniae 20
Radix Scutellariae 10 Fructus Gardeniaees 10 Olibanums 10 Pseudobulbus Bletillae (Rhizoma Bletillae) 10
Catechu 10 Flos Loniceraes 10 Radix Glycyrrhizaes 10 Corium elephatiss 10
6. by claim 4 or 5 described a kind of medicines for the treatment of burn and scald, it is characterized in that: described medicine is powder or ointment.
7. the described a kind of preparation method for the treatment of the medicine of burn and scald of claim 6, it is characterized in that: the preparation process of ointment is:
A. oil immersion, taking by weighing Rhizoma Coptidis, Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Sangusorbae, Herba Artemisiae Anomalae, Radix Arnebiae (Radix Lithospermi), the Radix Angelicae Dahuricae, the Flos Sophorae Immaturus, Galla Chinensis, Radix Angelicae Sinensis, the Radix Rehmanniae, Radix Scutellariae, Fructus Gardeniae, Olibanum, Pseudobulbus Bletillae (Rhizoma Bletillae), catechu, Flos Lonicerae, Radix Glycyrrhizae according to weight immerses in the Oleum sesami of 400-500 weight portion and soaked 8-24 hour
B. fried, be heated to oily temperature 120-150 ℃ above raw material is exploded to withered and yellow with steady fire, the elimination medicinal residues,
C. mix receipts cream, the Cera Flava of pulverizing 80-120 purpose Calamina (calcined and quenched), Gypsum Fibrosum Preparatum, Mirabilitum crystallina, Halloysitum Rubrum, Corium elephatis powder and 20 weight portions put into the cool back of Oleum sesami add Borneolum Syntheticum receipts cream,
D. pack.
8. the described a kind of preparation method for the treatment of the medicine of burn and scald of claim 6 is characterized in that:
The preparation process of powder is:
With all material medicine pulverize separately, wherein Radix Sangusorbae is replaced by charred Radix Sanguisorbae, packages spare behind the 80-120 order uniform mixing.
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| CN100420460C (en) * | 2006-01-06 | 2008-09-24 | 陈西成 | Chinese medicinal compsns. for treating burn and scald, its prepn. and usage |
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| CN108159238A (en) * | 2018-01-23 | 2018-06-15 | 党东汉 | Tissue regeneration ointment for curing burn |
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