CN105477618A - Compound ampelopsis grossedentata blood-pressure-lowering tea and preparation method thereof - Google Patents

Compound ampelopsis grossedentata blood-pressure-lowering tea and preparation method thereof Download PDF

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Publication number
CN105477618A
CN105477618A CN201610012605.1A CN201610012605A CN105477618A CN 105477618 A CN105477618 A CN 105477618A CN 201610012605 A CN201610012605 A CN 201610012605A CN 105477618 A CN105477618 A CN 105477618A
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China
Prior art keywords
blood
ampelopsis grossedentata
pressure
compound
preparation
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CN201610012605.1A
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Chinese (zh)
Inventor
云帆
康林芝
唐惠奇
王娜
秦艳
王玮
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GUANGZHOU AOJIAN FENGZE BIOLOGICAL TECHNOLOGY CO LTD
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GUANGZHOU AOJIAN FENGZE BIOLOGICAL TECHNOLOGY CO LTD
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Priority to CN201610012605.1A priority Critical patent/CN105477618A/en
Publication of CN105477618A publication Critical patent/CN105477618A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23FCOFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00Tea; Tea substitutes; Preparations thereof
    • A23F3/34Tea substitutes, e.g. matè; Extracts or infusions thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses compound ampelopsis grossedentata blood-pressure-lowering tea and a preparation method thereof. The compound ampelopsis grossedentata blood-pressure-lowering tea is prepared from ampelopsis grossedentata leaves, roxburgh rose fruits, liquorice, rhizoma zingiberis, radix puerariae and mulberries. The compound ampelopsis grossedentata blood-pressure-lowering tea has the effect of softening blood vessels, lowering blood pressure and the like, medicine-food-homologous type raw materials and food type raw materials are adopted, and the compound ampelopsis grossedentata blood-pressure-lowering tea has the advantages of being safe, free of toxic or side effect, free of dependence after being drunk for a long time and the like and is suitable for being applied and popularized.

Description

A kind of compound recipe Ampelopsis grossedentata blood-pressure decreasing tea and preparation method thereof
Technical field
The present invention relates to the application of Chinese medicine composition in treatment hypertension class disease, be specifically related to one and be used for the treatment of hypertensive compound recipe Ampelopsis grossedentata blood-pressure decreasing tea.
Background technology
In recent years, along with improving constantly of people's living standard, Hypertensive Population is increasing.Once suffer from hypertension, the state of an illness can only be suppressed by long-term taking antihypertensive drugs, usually based on Western medicine.But the problem that long-term taking Western medicine can develop immunity to drugs, patient requires more and more higher to medicine, and long-term taking also exists certain side effect, brings injury to patient body simultaneously.
Summary of the invention
The object of the invention is to the medicine above shortcomings part according to diseases such as existing treatment hypertension, now provide a kind of newly be used for the treatment of hypertensive compound recipe Ampelopsis grossedentata blood-pressure decreasing tea, the effect such as both had vessel softening, reduce blood pressure, also has the advantages such as Pure natural nontoxic side effect, no dependence.
Another object of the present invention is the preparation method providing above-mentioned compound recipe Ampelopsis grossedentata blood-pressure decreasing tea.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
A kind of compound recipe Ampelopsis grossedentata blood-pressure decreasing tea, is made up of the following crude drug according to mass percentage: Ampelopsis grossedentata leaf 30 ~ 40%, Single Roxburgh Rose Fruit 10 ~ 15%, Radix Glycyrrhizae 3 ~ 8%, Rhizoma Zingiberis 6 ~ 10%, Radix Puerariae 20 ~ 30% and Fructus Mori 6 ~ 10%.
The preparation method of compound recipe Ampelopsis grossedentata blood-pressure decreasing tea of the present invention is screened respectively by each crude drug, remove impurity and defective raw material thick, carry out cleaning, dry and pulverize rear for subsequent use respectively.By each raw material mix homogeneously, refill bag preparation, obtain compound recipe Ampelopsis grossedentata blood-pressure decreasing tea.
At every turn the using method of compound recipe Ampelopsis grossedentata blood-pressure decreasing tea of the present invention drinks 3g, brews, twice daily when drinking with more than 85 DEG C boiled water.
More than making packed blood-pressure decreasing tea is only that crude drug of the present invention is made more preferably dosage form, and all the other common dosage forms also can be selected, and its preparation process can slightly be distinguished according to different dosage form, but all belong to the common production process in this area, repeat no more herein.
Crude drug drug effect used in the present invention is as follows respectively:
Ampelopsis grossedentata leaf: resisting hypertension, cough-relieving, eliminate the phlegm, blood fat reducing, to protect the liver; Single Roxburgh Rose Fruit: clearing away heat and promoting production of body fluid, invigorating the stomach and promoting digestion, expelling summer-heat; Radix Glycyrrhizae: heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen; Rhizoma Zingiberis: warming middle-JIAO is by cold, and recuperating depleted YANG is promoted blood circulation, and controls trusted subordinate's cold type of pain, vomits and diarrhoea, cold extremities faint pulse, breathes with cough for cold time, anemofrigid-damp arthralgia, and yang deficiency is told, be defeated in battle, hematochezia; Radix Puerariae: improve immunity, strengthen myocardial contraction, protecting myocardial cell, reduces blood pressure, antiplatelet aggregation; Fructus Mori: nourishing YIN and benefiting blood, intestine moistening of promoting the production of body fluid.
Compared with prior art, the present invention has following beneficial effect:
(1) compound recipe Ampelopsis grossedentata blood-pressure decreasing tea of the present invention is pure natural raw material, and belong to integration of edible and medicinal herbs and foodstuff, not only have the effects such as blood pressure lowering, long-term drink has opsonic action to human body, does not have any toxic and side effects and dependency;
(2) described compound recipe Ampelopsis grossedentata blood-pressure decreasing tea is had vessel softening by the present invention, the effect such as reduce blood pressure.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described, but embodiment does not limit in any form the present invention.
Embodiment 1
By Ampelopsis grossedentata leaf 35g, Single Roxburgh Rose Fruit 13g, Radix Glycyrrhizae 6g, Rhizoma Zingiberis 10g, Radix Puerariae 28g, Fructus Mori 8g through cleaning, dry, pulverize after for subsequent use.By above-mentioned raw materials mix homogeneously, then pack, every bag of 3g, be mixed with Ampelopsis grossedentata blood-pressure decreasing tea.When drinking, brew with more than 85 DEG C boiled water, every bag can brew 3-4 time.
Embodiment 2
By Ampelopsis grossedentata leaf 32g, Single Roxburgh Rose Fruit 15g, Radix Glycyrrhizae 7g, Rhizoma Zingiberis 6g, Radix Puerariae 30g, Fructus Mori 10g through cleaning, dry, pulverize after for subsequent use.By above-mentioned raw materials mix homogeneously, then pack, every bag of 3g, be mixed with Ampelopsis grossedentata blood-pressure decreasing tea.When drinking, brew with more than 85 DEG C boiled water, every bag can brew 3-4 time.
Experimental example 1
Choose patient 400 people, all through clinical diagnosis be hypertension.Patient is divided into four groups, A group is blank group, and B group is the request for utilization number medicine that is the optimum proportioning of the blood-pressure decreasing tea drink formula disclosed in the application for a patent for invention of 200910306676.2 as a control group 1; C group is the request for utilization number medicine that is the optimum proportioning in the health-care tea disclosed in the application for a patent for invention of 201210002970.6 as a control group 2; D group is the blood-pressure decreasing tea that the embodiment of the present application 1 obtains.
Therapeutic effect is divided into effective, effective and invalid, is specially effective: diastolic pressure more than decline 1.3KPa, and reaches normal range; Though or diastolic pressure is not down to normally, more than decline 2.6KPa; Effective: diastolic pressure declines not as good as 1.3KPa, but reaches normal range; Or diastolic pressure comparatively treats the front 1.3 ~ 2.34KPa that declines, but do not reach normal range; Or systolic pressure comparatively treats front more than decline 4.0KPa; Invalid: not reach effective standard.
Medication is after 15 days, and result is as shown in table 1.
Table 1
Group A B C D
Effective 0 22 27 73
Effectively 0 35 49 26
Invalid 100 43 24 1
As shown in Table 1, gained oral liquid of the present invention is used for the treatment of hypertension, evident in efficacy, is much better than B group and C group.
Experimental example 2
The liver function of checking experiment example 1D group experimental subject, routine blood test, routine urinalysis and stool.Result shows, and the indices of experimental subject is and notes abnormalities, and therefore to show the safety of tooth Serpentis blood-pressure decreasing tea good for known compound recipe of the present invention.

Claims (2)

1. a compound recipe Ampelopsis grossedentata blood-pressure decreasing tea, is characterized in that being made up of the following crude drug according to mass percentage: Ampelopsis grossedentata leaf 30 ~ 40%, Single Roxburgh Rose Fruit 10 ~ 15%, Radix Glycyrrhizae 3 ~ 8%, Rhizoma Zingiberis 6 ~ 10%, Radix Puerariae 20 ~ 30% and Fructus Mori 6 ~ 10%.
2. the preparation method of compound recipe Ampelopsis grossedentata blood-pressure decreasing tea described in claim 1, after it is characterized in that comprising the steps: that each crude drug screens respectively, clean, dry, pulverizing, mix homogeneously, packs and get final product.
CN201610012605.1A 2016-01-05 2016-01-05 Compound ampelopsis grossedentata blood-pressure-lowering tea and preparation method thereof Pending CN105477618A (en)

Priority Applications (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770098A (en) * 2016-03-17 2016-07-20 天津元恒德科技有限公司 Blood pressure reducing composition and application thereof
CN113812621A (en) * 2020-07-14 2021-12-21 广东轻工职业技术学院 Compound plant wall-breaking powder and preparation method and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101642179A (en) * 2009-09-08 2010-02-10 项金秀 Tea beverage with functions of lowering pressure, lowering sugar and lowering fat
CN102499298A (en) * 2012-01-06 2012-06-20 雷雨田 Health care tea and preparation method thereof
CN102550756A (en) * 2011-12-29 2012-07-11 武汉龙族药号生物医药科技有限公司 Compound health-care tea containing vine tea and preparation method thereof
CN104186793A (en) * 2014-08-18 2014-12-10 贵州凤冈县仙人岭锌硒有机茶业有限公司 Health tea and preparation method thereof
CN104256009A (en) * 2014-09-27 2015-01-07 山东吴氏恒康健康科技有限公司 Tea containing radix puerariae and mulberry and preparation method of tea

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101642179A (en) * 2009-09-08 2010-02-10 项金秀 Tea beverage with functions of lowering pressure, lowering sugar and lowering fat
CN102550756A (en) * 2011-12-29 2012-07-11 武汉龙族药号生物医药科技有限公司 Compound health-care tea containing vine tea and preparation method thereof
CN102499298A (en) * 2012-01-06 2012-06-20 雷雨田 Health care tea and preparation method thereof
CN104186793A (en) * 2014-08-18 2014-12-10 贵州凤冈县仙人岭锌硒有机茶业有限公司 Health tea and preparation method thereof
CN104256009A (en) * 2014-09-27 2015-01-07 山东吴氏恒康健康科技有限公司 Tea containing radix puerariae and mulberry and preparation method of tea

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* Cited by examiner, † Cited by third party
Title
蒋力生等主编: "《中国药茶大全》", 31 August 2014, 上海科学技术出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770098A (en) * 2016-03-17 2016-07-20 天津元恒德科技有限公司 Blood pressure reducing composition and application thereof
CN113812621A (en) * 2020-07-14 2021-12-21 广东轻工职业技术学院 Compound plant wall-breaking powder and preparation method and application thereof

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Application publication date: 20160413