CN103705788B - A kind of Chinese medicine composition for the treatment of stomach-fire cauma type recurrent oral ulceration - Google Patents

A kind of Chinese medicine composition for the treatment of stomach-fire cauma type recurrent oral ulceration Download PDF

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CN103705788B
CN103705788B CN201410015000.9A CN201410015000A CN103705788B CN 103705788 B CN103705788 B CN 103705788B CN 201410015000 A CN201410015000 A CN 201410015000A CN 103705788 B CN103705788 B CN 103705788B
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stomach
parts
fire
chinese medicine
cauma
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CN103705788A (en
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李润红
王修丽
杜翠云
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Abstract

Treat a Chinese medicine composition for stomach-fire cauma type recurrent oral ulceration, this Chinese medicine composition is by Dendrobium jenkinsii Wall ex Lindl., flat Fructus Pruni pseudocerasi, Baphicacanthus cusia (Nees) Bremek., Folium et Caulis Indigoferae Tinctoriae, Radix Scutellariae, Caulis Bambusae In Taenia, Semen Firmianae, and Fructus Garciniae oblongifoliae, Gypsum Fibrosum is made.Clinical can be used for, treats stomach-fire cauma type recurrent oral ulceration.

Description

A kind of Chinese medicine composition for the treatment of stomach-fire cauma type recurrent oral ulceration
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of stomach-fire cauma type recurrent oral ulceration.
Background technology
Recurrent oral ulceration, also known as recurrent aphtha, is modal oral keritonocytes clinically, be occur in the grain of rice on oral mucosa to Semen Glycines size rounded or oval skin ulcer.Though the non-serious symptom of primary disease, often affects the feed of patient, speaks, affect quality of life.The doctor trained in Western medicine cause of disease and pathogenesis are failed to understand, think out of proportion with heredity, spirit, autoimmune, Copper in Body zinc at present, the factor such as zinc deficiency, microcirculation disturbance is relevant.Ulcer has periodicity, recurrent and self limiting feature, is apt to occur in lip, cheek, lingual margin etc.Doctor trained in Western medicine is based on topical therapeutic, and severe patient merges whole body therapeutic.Stomach-fire cauma type recurrent oral ulceration is clinical normal with thirst and desire for cold drink, bitter taste or smelly, red constipation of urinating, and food paddy is easily hungry, gingivitis or hemorrhage, ulcer surface many at gums up and down, buccal mucosa, lingual surface, pain very time then autonomous sialorrhea, red tongue, dry, rough and yellow fur or dry, the symptoms such as slippery and rapid pulse.Clinical Practice finds, Drug therapy stomach-fire cauma type recurrent oral ulceration of the present invention reaches good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine composition to the treatment stomach-fire cauma type recurrent oral ulceration of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, and adopt Dendrobium jenkinsii Wall ex Lindl., flat Fructus Pruni pseudocerasi, Baphicacanthus cusia (Nees) Bremek., Folium et Caulis Indigoferae Tinctoriae, Radix Scutellariae, Caulis Bambusae In Taenia, Semen Firmianae, Fructus Garciniae oblongifoliae, Gypsum Fibrosum is made, according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention to be made up of following raw material medicaments: Dendrobium jenkinsii Wall ex Lindl. 40-50 part, flat Fructus Pruni pseudocerasi 30-40 part, Baphicacanthus cusia (Nees) Bremek. 30-40 part, Folium et Caulis Indigoferae Tinctoriae 20-30 part, Radix Scutellariae 20-30 part, Caulis Bambusae In Taenia 10-20 part, Semen Firmianae 10-20 part, Fructus Garciniae oblongifoliae 10-20 part, Gypsum Fibrosum 10-20 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: Dendrobium jenkinsii Wall ex Lindl. 45 parts, 35 parts, flat Fructus Pruni pseudocerasi, Baphicacanthus cusia (Nees) Bremek. 35 parts, Folium et Caulis Indigoferae Tinctoriae 25 parts, Radix Scutellariae 25 parts, Caulis Bambusae In Taenia 15 parts, Semen Firmianae 15 parts, Fructus Garciniae oblongifoliae 15 parts, Gypsum Fibrosum 15 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Dendrobium jenkinsii Wall ex Lindl.: sweet, light, cool.Attach to the lung and stomach meridians.Nourishing the lung to arrest cough, tonifying-Yin and nourishing-stomach.Clinical in cough due to lung-heat, pulmonary tuberculosis, asthma, dysentery, stomatitis, stomachache, the diseases such as infantile malnutrition.
Flat Fructus Pruni pseudocerasi: bitter, micro-pungent, flat.Stomach function regulating, sore.Clinical in vomiting and diarrhoea of suffering from abdominal pain, angular cheilitis, traumatic injury.
Baphicacanthus cusia (Nees) Bremek.: bitter, salty, cold.Return lung, stomach, the heart, Liver Channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis.For high heat headache, send out speckle, cough due to lung-heat, hygropyretic dysentery, jaundice, measles, laryngopharynx swelling and pain, aphtha, mumps, spit blood, gingival hemorrhage, the diseases such as worm venom.
Folium et Caulis Indigoferae Tinctoriae: bitter, cold.Heat-clearing and toxic substances removing, cooling blood for hemostasis.For encephalitis B, parotitis, acute pharyngolaryngitis, lymphadenitis, conjunctival congestion, aphtha, erysipelas, worm venom etc.
Radix Scutellariae: bitter, cold, attaches to the lung and stomach meridians.Heat clearing and damp drying, eliminating fire and detoxication.Vexed for carbuncle sore tumefacting virus, damp and hot painful abdominal mass outward.
Caulis Bambusae In Taenia: sweet, be slightly cold, attaches to the lung and stomach meridians.Removing heat-phlegm, relieves restlessness and prevents vomiting.For the cough caused by expectorant heat or dysphoria and insomnia, gastropyretic vomiting etc.
Semen Firmianae: sweet, flat.GUIXIN, lung, stomach warp.Pleasant stomach function regulating, strengthening the spleen to promote digestion, hemostasis.For gastralgia, diarrhoea of getting ill from overeating, hernia, early whitening of beard and hair, the diseases such as oral aphthae in children.
Fructus Garciniae oblongifoliae: sweet, cool.Return spleen channel.Heat clearing away, promotes the production of body fluid.Clinical in gastric heat Tianjin wound, vomiting, thirsty, lung-heat QI rising in reverse order, cough is more than waits disease.
Gypsum Fibrosum: pungent, sweet, cold, nontoxic.Attach to the lung and stomach meridians.Expelling pathogenic factors from muscles for clearing heat, relieving restlessness is quenched the thirst.Do not move back for calentura high fever, vexed coma, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire is had a headache, toothache due to stomach-fire, aphtha of the mouth and tongue, the burning hot wound of soup etc.
Recurrent oral ulceration belongs to the category such as Chinese medicine " aphtha ", " erosion of the oral mucosa ", " aphtha ".Motherland's medical science is thought, due to eating and drinking without temperance, diseases caused by exogenous pathogenic factor six climate exopathogens, internal damage by the excessive seven emotions, the factors such as overstrain internal injury cause visceral dysfunction, accumulation of heat in the heart and spleen, the gastric heat deficiency of YIN and cause primary disease.Dendrobium jenkinsii Wall ex Lindl. tonifying-Yin and nourishing-stomach of the present invention, for monarch drug, flat Fructus Pruni pseudocerasi stomach function regulating, sore, Baphicacanthus cusia (Nees) Bremek. heat-clearing and toxic substances removing, cooling blood for hemostasis, for ministerial drug, Folium et Caulis Indigoferae Tinctoriae heat-clearing and toxic substances removing, cooling blood for hemostasis, Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, Caulis Bambusae In Taenia removing heat-phlegm, relieving restlessness, the pleasant stomach function regulating of Semen Firmianae, strengthening the spleen to promote digestion, Fructus Garciniae oblongifoliae's heat clearing away, promote the production of body fluid, Gypsum Fibrosum heat clearing away, relieving restlessness are quenched the thirst, compatibility reaches that clearing stomach expels the heat-evil jointly, YIN nourishing removing toxic substances, stomach function regulating sore effect, promote that topical ulcers heals very soon, reach the object for the treatment of stomach-fire cauma type recurrent oral ulceration.
Chinese medicine composition of the present invention is used in 2006 to 2013 the routine patients of clinical observation stomach-fire cauma type recurrent oral ulceration disease 103, and clinical report is as follows:
1, physical data
In 103 routine patients, women 62 example, male 41 example, at minimum 20 years old of age, maximum 69 years old, the course of disease was many at 3 months to 3 years, 35.6 years old mean age.
2, diagnostic criteria
With reference to " Chinese medical disease Standardization of diagnosis and curative effect ":
1. occur ulcer that is single or several diameter 3 ~ 5mm with oral mucosa, scorching hot pain is cardinal symptom;
2. onset is very fast, healing in general about 7 days, if down here, then the course of disease extends, normal easily recurrence more;
3. examination of mouth: stomatocace is comparatively shown shallow, circular or oval, quantity 1 ~ 2 at least, more than 10 at most, surface has faint yellow secretions to adhere to, and ulcer surrounding mucosa is mostly congested.
Stomach-fire cauma type recurrent oral ulceration clinical symptoms: thirst and desire for cold drink, bitter taste or smelly, red constipation of urinating, food paddy is easily hungry, gingivitis or hemorrhage, ulcer surface many at gums up and down, buccal mucosa, lingual surface, pain very time then autonomous sialorrhea, red tongue, dry, rough and yellow fur or dry, slippery and rapid pulse.
3, Therapeutic Method
3.1 prescriptions: Dendrobium jenkinsii Wall ex Lindl. 45g, flat Fructus Pruni pseudocerasi 35g, Baphicacanthus cusia (Nees) Bremek. 35g, Folium et Caulis Indigoferae Tinctoriae 25g, Radix Scutellariae 25g, Caulis Bambusae In Taenia 15g, Semen Firmianae 15g, Fructus Garciniae oblongifoliae 15g, Gypsum Fibrosum 15g.
3.2 preparation methoies: said medicine routinely technique makes decoction.
3.3 instructions of taking: each 1 dose, every day 2 times 5 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 with reference to " Chinese medical disease Standardization of diagnosis and curative effect ":
Cure: oral ulcer heals, local is without sense of discomfort;
Take a turn for the better: although have recurrence during oral ulcer, quantity reduces, and degree alleviates;
Do not heal: oral ulcer symptom and ulcer are without significant change.
4.2 results: in 103 routine patients, cure 65 examples (63.1%), 30 examples that take a turn for the better (29.1%), and do not heal 8 examples (7.8%), and total effective rate is 92.2%.
5, model case
5.1 Wang, man, 32 years old, oral ulcer more than 3 years, recurrent exerbation, rose one after another, once takes Chinese and western drugs and intramuscular injection interferon etc., and the state of an illness is without being clearly better.See time medical that there is the ulcer of two Semen Viciae fabae sample sizes on tongue body both sides, intermediate recess, surface is covered by white pod membrane, and in oral cavity, both sides also sporadically appear multiple aphtha, and surface is greyish white, and ambient color is light red.Red tongue, dry, rough and yellow fur or dry, slippery and rapid pulse.Take the Chinese medicine composition that the present invention treats stomach-fire cauma type recurrent oral ulceration to treat, after treating 1 course for the treatment of, patient mental is good, and ulcer improves gradually, takes medicine continuously 1 course for the treatment of afterwards, and recovery from illness, follows up a case by regular visits to and do not recur for 1 year again.
5.2 Zhangs, female, 36 years old, stomatocace 2 years, mostly was and is dispersed in distribution repeatedly, isolated circle or oval little fester, and diameter is about 2-3mm, red and swollen, causalgia, about 1 week ulcer self-heal.Time have the stomatocace of larger area, diameter is at about 5mm, and number is 1 or 2, and about 2-3 week could heal.Bitter taste or smelly, red constipation of urinating, red tongue, dry, rough and yellow fur or dry, slippery and rapid pulse.Taken the Chinese medicine composition that the present invention treats stomach-fire cauma type recurrent oral ulceration, 4 courses for the treatment of, disease obtains recovery from illness, follows up a case by regular visits to and does not recur for 1 year again.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, a kind of Chinese medicine composition for the treatment of stomach-fire cauma type recurrent oral ulceration, it is made up of following raw material medicaments: Dendrobium jenkinsii Wall ex Lindl. 40g, flat Fructus Pruni pseudocerasi 30g, Baphicacanthus cusia (Nees) Bremek. 30g, Folium et Caulis Indigoferae Tinctoriae 20g, Radix Scutellariae 20g, Caulis Bambusae In Taenia 10g, Semen Firmianae 10g, Fructus Garciniae oblongifoliae 10g, Gypsum Fibrosum 10g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of stomach-fire cauma type recurrent oral ulceration, it is made up of following raw material medicaments: Dendrobium jenkinsii Wall ex Lindl. 45g, flat Fructus Pruni pseudocerasi 35g, Baphicacanthus cusia (Nees) Bremek. 35g, Folium et Caulis Indigoferae Tinctoriae 25g, Radix Scutellariae 25g, Caulis Bambusae In Taenia 15g, Semen Firmianae 15g, Fructus Garciniae oblongifoliae 15g, Gypsum Fibrosum 15g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of stomach-fire cauma type recurrent oral ulceration, it is made up of following raw material medicaments: Dendrobium jenkinsii Wall ex Lindl. 50g, flat Fructus Pruni pseudocerasi 40g, Baphicacanthus cusia (Nees) Bremek. 40g, Folium et Caulis Indigoferae Tinctoriae 30g, Radix Scutellariae 30g, Caulis Bambusae In Taenia 20g, Semen Firmianae 20g, Fructus Garciniae oblongifoliae 20g, Gypsum Fibrosum 20g.

Claims (2)

1. treat a Chinese medicine composition for stomach-fire cauma type recurrent oral ulceration, it is characterized in that being made up of following crude drug:
Dendrobium jenkinsii Wall ex Lindl. 40-50 part, flat Fructus Pruni pseudocerasi 30-40 part, Baphicacanthus cusia (Nees) Bremek. 30-40 part, Folium et Caulis Indigoferae Tinctoriae 20-30 part, Radix Scutellariae 20-30 part, Caulis Bambusae In Taenia 10-20 part, Semen Firmianae 10-20 part, Fructus Garciniae oblongifoliae 10-20 part, Gypsum Fibrosum 10-20 part.
2. Chinese medicine composition according to claim 1, is characterized in that being made up of following crude drug:
Dendrobium jenkinsii Wall ex Lindl. 45 parts, 35 parts, flat Fructus Pruni pseudocerasi, Baphicacanthus cusia (Nees) Bremek. 35 parts, Folium et Caulis Indigoferae Tinctoriae 25 parts, Radix Scutellariae 25 parts, Caulis Bambusae In Taenia 15 parts, Semen Firmianae 15 parts, Fructus Garciniae oblongifoliae 15 parts, Gypsum Fibrosum 15 parts.
CN201410015000.9A 2014-01-14 2014-01-14 A kind of Chinese medicine composition for the treatment of stomach-fire cauma type recurrent oral ulceration Expired - Fee Related CN103705788B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1919320A (en) * 2006-08-19 2007-02-28 袁爱仙 Decoction medicine for treating stomatocace of heart-spleen heat accumulating type and its preparation method
CN101085242A (en) * 2007-06-29 2007-12-12 柴伟利 Traditional Chinese medicine composition for treating oral cavity ulcer
CN101797343A (en) * 2009-04-02 2010-08-11 殷猛 Chinese medicinal formula for treating oral cavity and throat diseases
CN103386068A (en) * 2013-08-04 2013-11-13 郝学江 Traditional Chinese medicinal preparation for treating oral inflammation and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1919320A (en) * 2006-08-19 2007-02-28 袁爱仙 Decoction medicine for treating stomatocace of heart-spleen heat accumulating type and its preparation method
CN101085242A (en) * 2007-06-29 2007-12-12 柴伟利 Traditional Chinese medicine composition for treating oral cavity ulcer
CN101797343A (en) * 2009-04-02 2010-08-11 殷猛 Chinese medicinal formula for treating oral cavity and throat diseases
CN103386068A (en) * 2013-08-04 2013-11-13 郝学江 Traditional Chinese medicinal preparation for treating oral inflammation and preparation method thereof

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