CN105456523A - Composition for rapidly repairing tissue wounds and relieving sensitivity and preparing method thereof - Google Patents

Abstract

The invention discloses a composition for rapidly repairing tissue wounds and relieving sensitivity and a preparing method thereof. The composition is mainly prepared from calcium, magnesium, zinc, potassium, selenium, lotus leaf extract, tea extract, guava leaf extract, angelica koreana extract, herba centellae extract, butanediol and water. By means of the composition for rapidly repairing tissue wounds and relieving sensitivity, generation of skin capillaries can be promoted, growth of tissues is facilitated, wound-surface nerve endings are protected, and pain is relieved. The composition has the effects of rapidly repairing wound tissues, easing pain, absorption heat, diminishing swelling, softening skin and improving scars.

Description

A kind of quick repair tissue wound and responsive composition and method of making the same of releiving

Technical field

The present invention relates to a kind of quick repair tissue wound and responsive composition and method of making the same of releiving.

Background technology

The shallow table scratch of skin surface is wound type common in orthopedic clinical work, especially common with body exposure positions such as facial areas.Have that wound area is comparatively large, easy infection, operative effect difference and route dressing change course for the treatment of is longer, focus easily forms the sequela such as cicatrix, pigment alteration after healing, the harm caused the body and mind of sufferer is larger.

Chinese patent CN102526121A, CN102698312A individually discloses the treatment of compositions to wound repair of different formulations, but this kind of medicine is limited by effective ingredient and can not plays good antiinflammatory bactericidal effect, even there is the risk that wound or wound inflammation are increased the weight of.

Summary of the invention

For deficiency existing in prior art, the present invention aims to provide a kind of quick repair tissue wound and responsive composition and method of making the same of releiving.

The present invention adopts following technical scheme to realize:

Quick repair tissue wound and a responsive compositions of releiving, it is mainly containing, for example lower component: calcium, magnesium, zinc, potassium, selenium, Folium Nelumbinis extract, Folium Camelliae sinensis extract, Folium Psidii Guajavae extract, Angelica gig extract, Herba Centellae extract, butanediol, water.

As preferably, the content of described quick repair tissue wound and the responsive each component of compositions of releiving is as follows: calcium 75000 ~ 76000mg/L, magnesium 6000 ~ 6100mg/L, zinc 2500 ~ 2600mg/L, potassium 1600 ~ 1650mg/L, selenium 12.0 ~ 14.0mg/Lsp, Folium Nelumbinis extract 1 ~ 3g/L, Folium Camelliae sinensis extract 2 ~ 5g/L, Folium Psidii Guajavae extract 1 ~ 2g/L, Angelica gig extract 3 ~ 5g/L, Herba Centellae extract 1 ~ 3g/L, butanediol 5 ~ 10wt%, surplus is water.

As preferably, the content of described quick repair tissue wound and the responsive each component of compositions of releiving is as follows: calcium 75300mg/L, magnesium 6087mg/L, zinc 2560mg/L, potassium 1620mg/L, selenium 13.6mg/Lsp, Folium Nelumbinis extract 2g/L, Folium Camelliae sinensis extract 4g/L, Folium Psidii Guajavae extract 1g/L, Angelica gig extract 4g/L, Herba Centellae extract 2g/L, butanediol 8wt%, surplus is water.

Above-described compositions is prepared into any dosage forms such as gel, and step is as follows:

1) each raw material is taken by formula;

2) each starting material with water being scattered in emulsifying pot in advance, then adding emulsifying agent, wetting agent, antiseptic, being heated with stirring to 80 DEG C to dissolving completely;

3) when stirring is cooled to below 45 DEG C, adds pH adjusting agent and regulate pH to 3 ~ 7, stir and both obtain.

The invention has the beneficial effects as follows:

Quick repair tissue wound of the present invention and responsive compositions of releiving can promote that skin capillary tube generates, and are conducive to tissue growth, and protection wound surface teleneuron, eases the pain.Have and repair wound tissue, analgesia, heat absorption detumescence, softening skin fast, improve scar, eliminate the effect of allergic symptom fast.

Detailed description of the invention

Further illustrate content of the present invention below by way of specific embodiment, but those skilled in the art should be able to know, described embodiment also limits the present invention never in any form.

embodiment 1

Quick repair tissue wound and a responsive compositions of releiving, the content of its each component is as follows: calcium 75300mg/L, magnesium 6087mg/L, zinc 2560mg/L, potassium 1620mg/L, selenium 13.6mg/Lsp, Folium Nelumbinis extract 2g/L, Folium Camelliae sinensis extract 4g/L, Folium Psidii Guajavae extract 1g/L, Angelica gig extract 4g/L, Herba Centellae extract 2g/L, butanediol 8wt%, surplus is water.

embodiment 2

Quick repair tissue wound and a responsive compositions of releiving, the content of its each component is as follows: calcium 75000mg/L, magnesium 6100mg/L, zinc 2500mg/L, potassium 1600mg/L, selenium 12.0mg/Lsp, Folium Nelumbinis extract 3g/L, Folium Camelliae sinensis extract 2g/L, Folium Psidii Guajavae extract 1g/L, Angelica gig extract 5g/L, Herba Centellae extract 1g/L, butanediol 5wt%, surplus is water.

embodiment 3

Quick repair tissue wound and a responsive compositions of releiving, the content of its each component is as follows: calcium 76000mg/L, magnesium 6000mg/L, zinc 2600mg/L, potassium 1650mg/L, selenium 14.0mg/Lsp, Folium Nelumbinis extract 1g/L, Folium Camelliae sinensis extract 5g/L, Folium Psidii Guajavae extract 2g/L, Angelica gig extract 3g/L, Herba Centellae extract 3g/L, butanediol 10wt%, surplus is water.

embodiment 4

Compositions described in embodiment 1 ~ 3 is prepared into gel, and step is as follows:

1) each raw material is taken by formula;

2) each starting material with water being scattered in emulsifying pot in advance, then adding emulsifying agent, wetting agent, antiseptic, being heated with stirring to 80 DEG C to dissolving completely;

3) when stirring is cooled to below 45 DEG C, adds pH adjusting agent and regulate pH to 3 ~ 7, stir and both obtain.

embodiment 5 clinical trial

Get the SD rat of 20 about 150g, be divided into experimental group 1 ~ 3 and matched group at random, four groups of rat backs do depilation process, after 75% alcohol disinfecting skin, respectively do the otch of a 1 × 1cm in both sides, back, blank group allows its self-heal, the skin wound repair hydrogel of the embodiment of the present invention 1 ~ 3 is smeared in experimental group wound bottom surface, respectively at 3,7,14 days record wound healing rates.Result shows, after having smeared skin wound repair hydrogel of the present invention, the healing rate of wound surface significantly improves (see table 1).

Table 1: the different disposal group rat skin wound healing rate of different time points record

From testing above, compositions of the present invention can repair tissue wound fast.

In addition, select 10 volunteers to use gel of the present invention to be applied to wound site respectively, wound site has ice-cold sensation, can ease the pain, have and repair wound tissue, analgesia, heat absorption detumescence, softening skin fast, improve scar, eliminate the effect of allergic symptom fast.

Claims (4)

1. quick repair tissue wound and a responsive compositions of releiving, it is mainly containing, for example lower component: calcium, magnesium, zinc, potassium, selenium, Folium Nelumbinis extract, Folium Camelliae sinensis extract, Folium Psidii Guajavae extract, Angelica gig extract, Herba Centellae extract, butanediol, water.

2. quick repair tissue wound according to claim 1 and responsive compositions of releiving, it is characterized in that, the content of each component is as follows: calcium 75000 ~ 76000mg/L, magnesium 6000 ~ 6100mg/L, zinc 2500 ~ 2600mg/L, potassium 1600 ~ 1650mg/L, selenium 12.0 ~ 14.0mg/Lsp, Folium Nelumbinis extract 1 ~ 3g/L, Folium Camelliae sinensis extract 2 ~ 5g/L, Folium Psidii Guajavae extract 1 ~ 2g/L, Angelica gig extract 3 ~ 5g/L, Herba Centellae extract 1 ~ 3g/L, butanediol 5 ~ 10wt%, surplus is water.

3. quick repair tissue wound according to claim 1 and 2 and responsive compositions of releiving, it is characterized in that, the content of each component is as follows: calcium 75300mg/L, magnesium 6087mg/L, zinc 2560mg/L, potassium 1620mg/L, selenium 13.6mg/Lsp, Folium Nelumbinis extract 2g/L, Folium Camelliae sinensis extract 4g/L, Folium Psidii Guajavae extract 1g/L, Angelica gig extract 4g/L, Herba Centellae extract 2g/L, butanediol 8wt%, surplus is water.

4. the compositions described in Claims 1 to 4 is prepared into any dosage forms such as gel, step is as follows:

1) each raw material is taken by formula;

2) each starting material with water being scattered in emulsifying pot in advance, then adding emulsifying agent, wetting agent, antiseptic, being heated with stirring to 80 DEG C to dissolving completely;

3) when stirring is cooled to below 45 DEG C, adds pH adjusting agent and regulate pH to 3 ~ 7, stir and both obtain.