CN105456404A - Method for preparing external use powder of medicine composition for accelerating burnt and scalded wound heeling - Google Patents
Method for preparing external use powder of medicine composition for accelerating burnt and scalded wound heeling Download PDFInfo
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- CN105456404A CN105456404A CN201510921840.6A CN201510921840A CN105456404A CN 105456404 A CN105456404 A CN 105456404A CN 201510921840 A CN201510921840 A CN 201510921840A CN 105456404 A CN105456404 A CN 105456404A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a method for preparing a medicine composition for accelerating burnt and scalded wound heeling, and relates to the technical field of traditional Chinese medicine. According to the method, 65 parts of polygonum cuspidatum root, 65 parts of herba portulacae, 33 parts of herba senecionis scandentis and 20 parts of lineate supplejack leaves are used as raw materials; and the medicine is respectively crushed, sieved and ground for preparing the medicine composition. When the medicine prepared according to the method is used for treating the burnt and scalded wound, the wound pain relieving is fast and exact; the wound heeling time is short; meanwhile, a use method is simple; and the expenditure of a patient is little.
Description
The application is the divisional application that applicant proposes " denomination of invention is: a kind of pharmaceutical composition and application thereof accelerating empyrosis wound surface healing, and the applying date is on June 20th, 2014, and application number is: 2014102780309 ".
Technical field
The invention belongs to technical field of Chinese medicine, in particular to a kind of pharmaceutical composition accelerating empyrosis wound surface healing.
Background technology
In daily life, the skin burn that accidentally causes because taking action or scald often can occur, the lighter's pain is rubescent, severe one is bubbled, and even exfoliation is downright bad, hinders to bone.As cured not in time, pathogenic factor and antibacterial invade, and not only can expand wound surface, skin ulceration, even cause infection, produce septicemia, cause death.At present, costly, treatment cycle is long for burn and scald, dermopathic western medical treatment, the difficulty and the burn and scald in rural area, dermatosis patient are sought medical advice, and process will scar not in time.
Summary of the invention
I am carrying out on the basis of discovery and arrangement absorption to all kinds of Chinese medical book, in conjunction with oneself medical skill handed down from one's ancestors and explore in the experience being engaged in traditional Chinese medical science infections section for many years a kind of can quickly alleviating pain, Shorten the Treatment Process the Chinese powder medicine of burn and scald.Based on this, the object of the present invention is to provide a kind of pharmaceutical composition and the application thereof of accelerating burn and scald.
The object of the present invention is achieved like this:
Accelerate a pharmaceutical composition for empyrosis wound surface healing, described pharmaceutical composition comprises the traditional Chinese medicinal material raw materials of following quality proportioning: polygoni cuspidati,radix 50-80 part, Herba Portulacae 50-80 part, Herba Senecionis Scandentis 28-40 part, Ramulus et Folium Berchemiae Lineatae 15-25 part.
Object of the present invention can also realize like this:
The pharmaceutical composition of described quickening empyrosis wound surface healing, it comprises the traditional Chinese medicinal material raw materials of following quality proportioning: polygoni cuspidati,radix 60-70 part, Herba Portulacae 60-70 part, Herba Senecionis Scandentis 31-36 part, Ramulus et Folium Berchemiae Lineatae 18-22 part.
The pharmaceutical composition of described quickening empyrosis wound surface healing, it is obtained by the traditional Chinese medicinal material raw materials of following quality proportioning: polygoni cuspidati,radix 64-66 part, Herba Portulacae 64-66 part, Herba Senecionis Scandentis 32-34 part, Ramulus et Folium Berchemiae Lineatae 19-21 part.
In a most preferred embodiment of the present invention, the pharmaceutical composition of described quickening empyrosis wound surface healing, it is obtained by the traditional Chinese medicinal material raw materials of following quality proportioning: polygoni cuspidati,radix 65 parts, Herba Portulacae 65 parts, Herba Senecionis Scandentis 33 parts, Ramulus et Folium Berchemiae Lineatae 20 parts.
In a large amount of clinical practices, the pharmaceutical composition of quickening empyrosis wound surface healing of the present invention, it is with external pulvis administration, and therefore request of the present invention protection adopts Chinese powder medicine prepared by above-mentioned traditional Chinese medicinal material raw materials.
The present invention prepares the method for the pharmaceutical composition external pulvis accelerating empyrosis wound surface healing, and the method comprises the steps:
(1) polygoni cuspidati,radix of recipe quantity, Herba Portulacae, Herba Senecionis Scandentis and Ramulus et Folium Berchemiae Lineatae is taken respectively, broken with last medicated powder, cross 100 mesh sieves;
(2) put in mortar by polygoni cuspidati,radix granule, fully grind, inclining, it is for subsequent use;
(3) get the Herba Portulacae after pulverizing, Herba Senecionis Scandentis and Ramulus et Folium Berchemiae Lineatae and to put in mortar grinding evenly, then add polygoni cuspidati,radix powder, grind well, consistent to color even, incline and to pack.
The present invention is found by a large amount of clinical practice, the traditional Chinese medicinal material raw materials compositions be made up of polygoni cuspidati,radix, Herba Portulacae, Herba Senecionis Scandentis and Ramulus et Folium Berchemiae Lineatae, and during its treatment for burn and scald, wound surface pain relieving is definite rapidly, and wound healing time is short.Therefore, present invention also offers a kind of new pharmaceutical use, that is: the application of above-mentioned traditional Chinese medicinal material raw materials compositions in the medicine of preparation treatment burn and scald.
The using method that the present invention accelerates the pharmaceutical composition of empyrosis wound surface healing is: be first applied to injury with Oleum Sesami is very thin, Chinese powder medicine prepared by rear the present invention is even is spread on affected part, and with the wrapping of health gauze, every day changes dressings once, until recovery from illness.
The medicinal composition powders tool that the present invention relates to has the following advantages and marked improvement:
(1), during treatment for burn and scald, wound surface pain relieving is definite rapidly, and wound healing time is short;
(2) treatment burn is very inexpensive, than general treatment as about low by 70% with the more medical expenses for medicine such as MEIBAO SHIRUN SHAOSHANG GAO, compares medical expense about low by 80% with tertiary hospitals;
(3) usage is simple, directly acts on impaired wound surface, avoids the toxic and side effects used in a large number caused by antibiotic, and patient is easy to accept.
Detailed description of the invention
Be below the concrete preparation embodiment of the present invention and clinical practice example, technical scheme of the present invention done and makes describing and validating further.It should be noted that, traditional Chinese medicinal material raw materials of the present invention has following source: polygoni cuspidati,radix selects the dry root of polygonaceae plant Rhizoma Polygoni Cuspidati PolygonumcuspidatumSieb.etZucc..Herba Portulacae selects the drying children young stem and leaf of portulacaceous plant Herba Portulacae.Herba Senecionis Scandentis selects the dry herb of Compositae Senecio plant Herba Senecionis Scandentis SenecioscandensBuch.-Ham..Ramulus et Folium Berchemiae Lineatae selects the dry young stem and leaf of Rhamnaceae plant Ramulus et Folium Berchemiae Lineatae Berchemialineata (L.) DC..
Embodiment 1
(1) polygoni cuspidati,radix 650g is taken respectively, Herba Portulacae 650g, Herba Senecionis Scandentis 330g, Ramulus et Folium Berchemiae Lineatae 200g, broken with last medicated powder, cross 100 mesh sieves;
(2) put in mortar by polygoni cuspidati,radix granule, fully grind, inclining, it is for subsequent use;
(3) get the Herba Portulacae after pulverizing, Herba Senecionis Scandentis and Ramulus et Folium Berchemiae Lineatae and to put in mortar grinding evenly, then add polygoni cuspidati,radix powder, grind well, consistent to color even, incline and to pack.
Embodiment 2
(1) polygoni cuspidati,radix 700g is taken respectively, Herba Portulacae 800g, Herba Senecionis Scandentis 360g, Ramulus et Folium Berchemiae Lineatae 250g, broken with last medicated powder, cross 100 mesh sieves; (2) put in mortar by polygoni cuspidati,radix granule, fully grind, inclining, it is for subsequent use;
(3) get the Herba Portulacae after pulverizing, Herba Senecionis Scandentis and Ramulus et Folium Berchemiae Lineatae and to put in mortar grinding evenly, then add polygoni cuspidati,radix powder, grind well, consistent to color even, incline and to pack.
Embodiment 3
(1) polygoni cuspidati,radix 800g is taken respectively, Herba Portulacae 700g, Herba Senecionis Scandentis 400g, Ramulus et Folium Berchemiae Lineatae 220g, broken with last medicated powder, cross 100 mesh sieves;
(2) put in mortar by polygoni cuspidati,radix granule, fully grind, inclining, it is for subsequent use;
(3) get the Herba Portulacae after pulverizing, Herba Senecionis Scandentis and Ramulus et Folium Berchemiae Lineatae and to put in mortar grinding evenly, then add polygoni cuspidati,radix powder, grind well, consistent to color even, incline and to pack.
Embodiment 4
(1) polygoni cuspidati,radix 500g is taken respectively, Herba Portulacae 500g, Herba Senecionis Scandentis 280g, Ramulus et Folium Berchemiae Lineatae 150g, broken with last medicated powder, cross 100 mesh sieves;
(2) put in mortar by polygoni cuspidati,radix granule, fully grind, inclining, it is for subsequent use;
(3) get the Herba Portulacae after pulverizing, Herba Senecionis Scandentis and Ramulus et Folium Berchemiae Lineatae and to put in mortar grinding evenly, then add polygoni cuspidati,radix powder, grind well, consistent to color even, incline and to pack.
The effectiveness study of embodiment 5 Chinese powder medicine treatment burned patient
Superficial bums, scald patient 60 example, be all male, age 20-60 year; 21 examples of burn surface area 1%-5%, 27 examples of 6%-1O%, 12 examples of 11%-20%; Boiling water burn 42 example, fire burn 18 example.All patients be divided at random test A group and test B group each 30 routine, two groups in age, burn and scald area and burn and scald type without significant difference, there is comparability.
The nursing of patient and medication: wound surface dirt is cleaned thoroughly, exposes wound surface completely.First fully rinse wound surface with tap water, then with the clean wound surface of normal saline flushing, then rinse (not using other disinfectant to clear up wound surface) with povidone iodine.Vesicle retains as far as possible for a long time, and huge blister should puncture (blister low level) drawing liquid, discharge opeing, notes retaining bubble skin, and direct drug injection, is administered to wound healing.
Test A group patient is first applied to injury with Oleum Sesami is very thin, and polygoni cuspidati,radix powder prepared by rear embodiment 1 is evenly spread on affected part, and with the wrapping of health gauze, every day changes dressings once.
Test B group patient is first applied to injury with Oleum Sesami is very thin, and the Chinese powder medicine prepared of rear embodiment 1 four Chinese medicine material is even is spread on affected part, and wrap up with health gauze, every day changes dressings once.
53 routine patients are after the treatment of homemade traditional Chinese drug burn oil, and pain disappearing time, wound healing time are as shown in the table.
A table 1 liang group patient pain disappears and wound healing time compares
Compare with test A group,
★ p< 0.05;
★ ★ p< 0.01.
Model case: Wu, male, 31 years old, fall down after supper on the iron ore of the high heat of high temperature when going to work in workshop on July 2nd, 2011, scalded burn right lower extremity area about 14% by iron ore, wound surface is redly to hold concurrently mutually in vain, and edema is obvious, and the blister differed in size as seen, include the Superficial bums wound surface of faint yellow supernatant liquid.Patient processes by the method for above-mentioned test B group, treats second day wound surface and oozes out on a small quantity, and the 5th day wound surface has a small amount of skin graft and formed, and within the 6th day, wound surface entirety reduces, and oozes out minimizing, and the skin graft of existing 2/3 covers granulation tissue.
Claims (1)
1. a method for the pharmaceutical composition external pulvis of empyrosis wound surface healing is accelerated in preparation, it is characterized in that comprising following processing step:
(1) polygoni cuspidati,radix 65 parts is taken by mass parts, Herba Portulacae 65 parts, Herba Senecionis Scandentis 33 parts, Ramulus et Folium Berchemiae Lineatae 20 parts, broken with last medicated powder, cross 100 mesh sieves;
(2) put in mortar by polygoni cuspidati,radix granule, fully grind, inclining, it is for subsequent use;
(3) get the Herba Portulacae after pulverizing, Herba Senecionis Scandentis and Ramulus et Folium Berchemiae Lineatae and to put in mortar grinding evenly, then add polygoni cuspidati,radix powder, grind well, consistent to color even, incline and to pack.
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CN201410278030.9A CN104000894B (en) | 2014-06-20 | 2014-06-20 | A kind of pharmaceutical composition and application thereof accelerating empyrosis wound surface healing |
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CN201510921840.6A Withdrawn CN105456404A (en) | 2014-06-20 | 2014-06-20 | Method for preparing external use powder of medicine composition for accelerating burnt and scalded wound heeling |
CN201410278030.9A Active CN104000894B (en) | 2014-06-20 | 2014-06-20 | A kind of pharmaceutical composition and application thereof accelerating empyrosis wound surface healing |
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CN104224989A (en) * | 2014-09-29 | 2014-12-24 | 麻江县生产力促进中心有限责任公司 | Traditional Chinese medicine for treating burn and scald |
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CN1457812A (en) * | 2002-05-17 | 2003-11-26 | 盛杰 | Chinese medicinal tincture for curing burn and scald and its preparing method |
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WO2007136773A1 (en) * | 2006-05-18 | 2007-11-29 | Biobotanic Corp. | Topical herbal formulations |
CN103566112A (en) * | 2012-07-18 | 2014-02-12 | 马千里 | External traditional Chinese medicine paste for treating burns and scalds, and preparation method thereof |
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CN1457812A (en) * | 2002-05-17 | 2003-11-26 | 盛杰 | Chinese medicinal tincture for curing burn and scald and its preparing method |
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CN104000894A (en) | 2014-08-27 |
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Application publication date: 20160406 |