CN105456174B - The preparation method of cosmetic additive agent, cosmetic additive agent and include its cosmetics - Google Patents
The preparation method of cosmetic additive agent, cosmetic additive agent and include its cosmetics Download PDFInfo
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- CN105456174B CN105456174B CN201511023241.9A CN201511023241A CN105456174B CN 105456174 B CN105456174 B CN 105456174B CN 201511023241 A CN201511023241 A CN 201511023241A CN 105456174 B CN105456174 B CN 105456174B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
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Abstract
The present invention provides a kind of preparation method of cosmetic additive agent, cosmetic additive agent and includes its cosmetics, and the preparation method comprises the following steps：1) by after jellyfish desalting processing, processing is hydrolyzed using acidic hydrolysis agent and basic hydrolysis agent, obtains acid viscous fluid and alkaline viscous fluid；2) acid viscous fluid and alkaline viscous fluid are subjected to separating treatment respectively, obtain acid clear liquid and alkaline clear liquid, acid clear liquid and alkaline clear liquid are merged, obtain mixing clear liquid；3) impurity will be removed after mixing clear liquid concentration, obtains jellyfish extract；4) jellyfish extract is mixed with carbohydrate isomer (Pentavitin), obtains cosmetic additive agent.By the present invention cosmetic additive agent be applied to cosmetics in, can depth water lock moisturizing, skin can be made enduringly to possess moisture, even can also pin skin moisture in the case where relative humidity is relatively low, so as to alleviate or solve the problems, such as the drying of skin.
Description
Technical field
The present invention relates to a kind of preparation method of cosmetic additive agent, cosmetic additive agent and its cosmetics are included, are belonged to
In field of daily chemicals.
Background technology
Water, is Source of life, is also the beautiful source of skin.Healthy and beautiful skin should be full and plentiful, Mei Gexi
Born of the same parents' moisture is sufficient, and the colour of skin and gloss of health is presented, and dermatoglyph is orderly, and physiological function perfects；And cell water shortage can be led
The generation of dry line is caused, in addition it is dark and gloomy as permanent wrinkle, and the colour of skin, and dermatoglyph is mixed and disorderly, or even physiological function (example
Such as：Metabolism, excretion) missing.
Influence water content skin health whether key factor is skin.The water content of usual epidermis and corium is about
75%；The water content of cuticula is the state that 10-20% skin can show health, typically not less than 10%.Cuticula
If the problem of less than 10%, dry skin occurs in water content, such as wrinkle, decortication, dark and gloomy etc..
In recent years, with the transition of weather, the deterioration of environment, and the cognition to skin senescence reason, the drying of skin
Problem has turned into a big puzzlement.Numerous cosmetics consumers and cosmetics researcher are intended to can solve the problem that or alleviate skin
The drying problem of skin.At present, the moisturizer of existing more moisturizing class on the market, but due to dry skin be not only by
What moisturizing can solve the problem that, cause the effect of long-term moisturizing barely satisfactory.
The content of the invention
Problems to be solved by the invention
The present invention provides a kind of preparation method of cosmetic additive agent, cosmetic additive agent and includes its cosmetics, this
The cosmetic additive agent of invention can depth water lock moisturizing, skin can be made enduringly to possess moisture, even in relative humidity
Also skin moisture can be pinned in the case of relatively low, so as to alleviate or solve the problems, such as the drying of skin.
The solution used to solve the problem
The present invention provides a kind of preparation method of cosmetic additive agent, comprises the following steps：
1) by after jellyfish desalting processing, processing is hydrolyzed using acidic hydrolysis agent and basic hydrolysis agent, obtained acid viscous
Magma and alkaline viscous fluid；
2) the acid viscous fluid and the alkaline viscous fluid are subjected to separating treatment respectively, obtain acid clear liquid and alkalescence
Clear liquid, the acid clear liquid and the alkaline clear liquid are merged, obtain mixing clear liquid；
3) impurity will be removed after the mixing clear liquid concentration, obtains jellyfish extract；
4) the jellyfish extract is mixed with carbohydrate isomer (Pentavitin), obtains cosmetic additive agent.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the desalting processing includes：Jellyfish is placed in
Immersion treatment in ionized water.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the jellyfish of every 1 parts by weight adds 2-6 weights
Measure the deionized water of part, preferably 3-5 parts by weight.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the treatment conditions of the immersion treatment are：In room
Temperature is lower to soak, and at interval of 0.5-4 hours, preferably 1-2 hours change a deionized water, and immersion number is 3-15 times, preferably 6-10
It is secondary.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the treatment conditions of the hydrolysis process are：Every 1
The jellyfish of parts by weight adds the acidic hydrolysis agent of 3-6 parts by weight and the basic hydrolysis agent of 3-6 parts by weight, excellent in 0.1-0.6MPa
Under the pressure for selecting 0.3-0.5MPa, Hydrolysis At Room Temperature 0.5-2 hours, preferably 0.8-1.2 hours, hydrolyze 2-6 times, preferably 3-5 times.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the acidic hydrolysis agent and basic hydrolysis agent
Concentration is 1-5mol/L, preferably 1.5-2.5mol/L.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the hydrolysis process is first to use basic hydrolysis agent
Hydrolysis, then hydrolyzed with acidic hydrolysis agent；Or first hydrolyzed with acidic hydrolysis agent, then hydrolyzed with basic hydrolysis agent.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the acidic hydrolysis agent is hydrochloric acid solution, sulfuric acid
Solution, salpeter solution；The basic hydrolysis agent is potassium hydroxide solution, sodium hydroxide solution, calcium hydroxide suspension.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, in the cosmetic additive agent, the jellyfish carries
The weight ratio for taking thing and carbohydrate isomer is 1-20：0.001-10, preferably 3-15：0.05-8.
The present invention also provides a kind of cosmetic additive agent, and it is prepared by the preparation method of the cosmetic additive agent of the present invention
Obtain.
The present invention is also carried for a kind of cosmetics of the cosmetic additive agent comprising the present invention, including：
The cosmetic base of 70-98.999 parts by weight,
The cosmetic additive agent of 1.001-30 parts by weight；
Wherein, the gross weight based on the cosmetics, the carbohydrate isomer in the cosmetic additive agent
(Pentavitin) addition is 0.001-10 parts by weight, preferably 0.05-8 parts by weight, in the cosmetic additive agent
The addition of the jellyfish extract is 1-20 parts by weight, preferably 3-15 parts by weight.
According to the cosmetics of the present invention, wherein, the cosmetic base is skin care cream, moisturizing lotion, moisture retention water, skin care
Elite, mildy wash or eye essence.
The effect of invention
The cosmetic additive agent that the preparation method of the present invention is obtained is added in cosmetics, and the water of skin can be pinned with depth
Point, even in the relatively low environment of relative humidity, skin moisture can be also kept for a long time, make skin will not be because of the influence of environment
And water shortage is dried, so as to keep the moisture of skin for a long time and moisten degree, and improve skin elasticity.
Brief description of the drawings
Fig. 1 is the face cream I of the embodiment of the present invention 1 and the face cream III of comparative example 1 skin in moisture content of skin test
The contrast curve of moisture growth rate change；
Fig. 2 is the face cream I of the embodiment of the present invention 1 and the face cream III of comparative example 1 skin in percutaneous water loss test
The contrast curve of skin water loss change.
Embodiment
The invention provides a kind of preparation method of cosmetic additive agent, comprise the following steps：
1) by after jellyfish desalting processing, processing is hydrolyzed using acidic hydrolysis agent and basic hydrolysis agent, obtained acid viscous
Magma and alkaline viscous fluid；
2) the acid viscous fluid and alkaline viscous fluid are subjected to separating treatment respectively, obtain acid clear liquid and alkalescence is clear
Liquid, the acid clear liquid and the alkaline clear liquid are merged, obtain mixing clear liquid；
3) impurity will be removed after the mixing clear liquid concentration, obtains jellyfish extract；
4) the jellyfish extract is mixed with carbohydrate isomer (Pentavitin), obtains cosmetic additive agent.
Jellyfish is the macroplankton in ocean, and species is various, is globally distributed the waters of various regions.In the body of jellyfish
Interior, water accounts for the 96% of its body weight, and the protein backbone of itself accounts for 0.3%, and remaining solid phase is the ore deposit of similar seawater component
Material.Although only there are about 4% skelemin matter and mineral matter in medusoma, this small number of protein and mineral matter foot
To retain its internal 96% moisture.By the present invention preparation method, can obtain in medusoma by protein and mineral
The solid-phase component that matter collectively constitutes.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the desalting processing includes：Jellyfish is placed in
Immersion treatment in ionized water.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the pH value of the water is 3-8, every 1 parts by weight
The jellyfish adds the deionized water of 2-6 parts by weight, preferably 3-5 parts by weight.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the treatment conditions of the immersion treatment are：In room
Temperature is lower to soak, and at interval of 0.5-4 hours, preferably 1-2 hours change a deionized water, and immersion number is 3-15 times, preferably 6-10
It is secondary.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the reaction condition of the hydrolysis process is：Every 1
The jellyfish of parts by weight adds the acidic hydrolysis agent of 3-6 parts by weight and the basic hydrolysis agent of 3-6 parts by weight, excellent in 0.1-0.6MPa
Under the pressure for selecting 0.3-0.5MPa, hydrolyze 2-6 times, preferably 3-5 times.
According to the preparation method of the cosmetic additive agent of the present invention, wherein it is preferred to, the acidic hydrolysis agent and alkaline water
The concentration for solving agent is 1-5mol/L, preferably 1.5-2.5mol/L.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the hydrolysis process can be first to use alkaline water
Agent hydrolysis is solved, then is hydrolyzed with acidic hydrolysis agent；Or first hydrolyzed with acidic hydrolysis agent, then hydrolyzed with basic hydrolysis agent.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, the acidic hydrolysis agent is hydrochloric acid solution, sulfuric acid
Solution, salpeter solution；The basic hydrolysis agent is potassium hydroxide solution, sodium hydroxide solution, calcium hydroxide suspension.
According to the preparation method of the cosmetic additive agent of the present invention, wherein, in the cosmetic additive agent, the jellyfish carries
The weight ratio for taking thing and carbohydrate isomer is 1-20：0.001-10, preferably 3-15：0.05-8.
Preferably, according to the preparation method of the cosmetic additive agent of the present invention, comprise the following steps：
(1) after jellyfish is drained away the water, it is dipped in deionized water and soaks, the weight of the deionized water is jellyfish weight
3 times, change a deionized water at interval of 1-2 hours, soak 6-10 times, slough entrained by jellyfish salinity (such as：Sodium chloride).
(2) by the draining again of the jellyfish after immersion, first with 1.5-2.5mol/L potassium hydroxide solution in 0.3- under normal temperature
Hydrolysis At Room Temperature under 0.5MPa pressure, the weight of the potassium hydroxide solution are 3~6 times of jellyfish weight, and hydrolysis 0.8-1.2 is small
When after leach alkaline viscous fluid, hydrolyzed again with 3~6 times of potassium hydroxide solution that weight is jellyfish weight, altogether using 1.5-
2.5mol/L potassium hydroxide solution hydrolyzes 3-5 times.
(3) and then with 1.5-2.5mol/L hydrochloric acid solution continue to hydrolyze, the amount of the hydrochloric acid solution is the 3 of jellyfish weight
~6 times, acid viscous fluid is leached after hydrolyzing 0.8-1.2 hours, again with 3~6 times of the hydrochloric acid solution that weight is jellyfish weight
Hydrolysis, then hydrolyzed 3-5 times using 1.5-2.5mol/L hydrochloric acid solution.
(4) collect that 3 potassium hydroxide solutions hydrolyze obtained alkaline viscous fluid and 3 hydrochloric acid solutions hydrolyze obtained acidity
Viscous fluid, homogeneous, centrifugal treating, obtain acid clear liquid and alkaline clear liquid (i.e. respectively：Acid clear liquid and alkaline clear liquid), by gained
The acid clear liquid arrived and alkaline clear liquid merge, and obtain mixing clear liquid, are filtered after concentration, add appropriate preservative and obtain jellyfish and carry
Take thing.
(5) resulting jellyfish extract is mixed with carbohydrate isomer (Pentavitin), obtains cosmetics and add
Add agent, wherein, the weight ratio of the jellyfish extract and carbohydrate isomer is 3-15：0.05-8.
Include jellyfish extract and carbohydrate isomer (Pentavitin) in the cosmetic additive agent of the present invention.It is logical
Skin moisture can be pinned by crossing jellyfish extract, reduce percutaneous water loss.Jellyfish is grown in big marine, the bone that protein is formed
Mineral matter in frame and seawater collectively constitutes 4% solid-phase component, supports and maintain enough juicies of percentage of liveweight 96%.Water
Female extract only proximate to the composition of seawater, can not provide mineral matter for cuticula, promote epidermal cell keratinization, can also swash
Epidermal cell living, strengthen the barrier function of skin.Jellyfish also contains protein, can increase filaggrin in cuticula
(Filaggrin) content, promote amino acid content in cuticula to increase, supplement the NMF of skin, increase cutin
The moisture of layer, so as to strengthen the water lock ability of skin.
Carbohydrate isomer (Pentavitin), from vegetalitas D-Glucose, contain glucose, fructose, sweet dew
The compositions such as sugar, galactolipin, psicose.Loricrin can be improved by adding carbohydrate isomer (Pentavitin)
(Loricrin) expression of gene, the function of hornification coating is influenceed；ASM gene expression can also be improved
Level, stimulate the synthesis of ceramide；The gene expression dose of a polyprotein and hyaluronic acid synthase 3 can be improved, is promoted
NMF NMF and hyaluronic acid combination, so as to improve skin moisturizing ability.
Further, since the ammonia in carbonyl and skin keratin in the sugared structure of carbohydrate isomer (Pentavitin)
Base is combined, and is made carbohydrate isomer (Pentavitin) closely coupled with keratin, is not easy to be washed off, only at skin angle
It can be just removed when matter layer comes off naturally, so that carbohydrate isomer (Pentavitin) can enduringly play depth
The function of water lock and water conservation.
The present invention also provides a kind of cosmetic additive agent, and it is prepared by the preparation method of the cosmetic additive agent of the present invention
Obtain.
The present invention also provides a kind of cosmetics, and it includes：
The cosmetic base of 70-98.999 parts by weight,
1.001-30 the cosmetic additive agent of parts by weight；
Wherein, the gross weight based on the cosmetics, the addition of the carbohydrate isomer is 0.001-10 weight
Part, preferably 0.05-8 parts by weight, the addition of the jellyfish extract is 1-20 parts by weight, is preferably 3-15 parts by weight.
The present invention cosmetic additive agent, can depth water lock moisturizing, skin can be made enduringly to possess moisture, even
Skin moisture can be also pinned in the case where relative humidity is relatively low, so as to alleviate or solve the problems, such as the drying of skin.
According to the present invention cosmetics, wherein, the cosmetic base can be skin care cream, moisturizing lotion, moisture retention water,
Facial treatment essence, mildy wash or eye essence.
Butyrospermum parkii fruit fat, tocopherol acetate, trimethylglycine, hyalomitome can be added in the cosmetic base
One or more in the common NMF such as sour sodium, and other usual ingredients in cosmetics.The material foundation specifically added
Depending on the cosmetics to be prepared.
According to the cosmetics of the present invention, also include auxiliary material in the cosmetics, the auxiliary material includes auxiliary agent and water.
The present invention also provides a kind of preparation method of cosmetics of the invention, and it includes mixing each component of the cosmetics
The step of conjunction.
Embodiment
With reference to embodiment, the invention will be further described, but protection scope of the present invention is not limited to this.This hair
Bright carbohydrate isomer (Pentavitin) is purchased from French DSM (DSM) company.The raw material sources city of jellyfish extract
Product is sold, commercially available jellyfish, acid-base reagent (analysis is pure), the deionized water of Binding experiment room and equipment carry out extraction preparation.
In the application, remaining component used in embodiment is commercially available prod, can be easily commercially available.
Embodiment 1
Cosmetic additive agent I preparation：
(1) jellyfish of 5 parts by weight to drain away the water is dipped in deionized water and soaked, the weight of the deionized water is water
3 times of female weight, a deionized water was changed at interval of 1 hour, soaks 10 times, sloughs the salinity (sodium chloride) entrained by jellyfish.
(2) by the draining again of jellyfish after desalting processing, under normal temperature with 2mol/L potassium hydroxide solution 0.3MPa pressure
Hydrolysis At Room Temperature under power, the weight of the potassium hydroxide solution are 6 times of jellyfish weight, and hydrolysis leaches alkaline viscous fluid after 1 hour,
Hydrolyzed again with 6 times of the potassium hydroxide solution that weight is jellyfish weight, hydrolyze 3 using 2mol/L potassium hydroxide solution altogether
It is secondary.
(3) and then with 2mol/L hydrochloric acid solution continue to hydrolyze, the amount of the hydrochloric acid solution is 6 times of jellyfish weight, water
Solution leaches acid viscous fluid after 1.2 hours, is hydrolyzed again with 6 times of the hydrochloric acid solution that weight is jellyfish weight, altogether using 2mol/
L hydrochloric acid solution hydrolyzes 3 times.
(4) collect that 3 potassium hydroxide solutions hydrolyze obtained alkaline viscous fluid and 3 hydrochloric acid solutions hydrolyze obtained acidity
Viscous fluid, homogeneous, centrifugal treating, obtain acid clear liquid and alkaline clear liquid, by resulting acid clear liquid and alkaline clear liquid respectively
Merge, obtain mixing clear liquid, filtered after the mixing clear liquid is concentrated into 25 parts by weight, add appropriate preservative Phenoxyethanol i.e.
Obtain jellyfish extract I.
(5) by the carbohydrate isomer of the resulting jellyfish extract I of 15 parts by weight and 0.1 parts by weight
(Pentavitin) mix, obtain cosmetic additive agent I.
Face cream I preparation：
Active component：By the fourth of 5 parts by weight in the cosmetic additive agent I of 5 parts by weight and face cream I cosmetic base
Glycol, the glycerine of 8 parts by weight, the Sodium Hyaluronate of 0.04 parts by weight, 3 parts by weight polyglycerolmethacrylate (and) the third two
Alcohol (and) Gantrez AN-119 is well mixed, as water miscible active component；By 2 weights in face cream I cosmetic base
The Butyrospermum parkii fruit fat, the tocopherol acetate of 2 parts by weight of amount part are well mixed, as oil-soluble active component.
Auxiliary material in face cream I cosmetic base：The oil phase of 7 parts by weight has cyclomethicone, 3 parts by weight
Caprylic/capric triglyceride, the octyl group polymethyl siloxane of 2 parts by weight, tribehenin essence PEG-20 esters, 1 weight of 2 parts by weight
The stearine, the stearic acid of 0.8 parts by weight, the cetostearyl alcohol of 0.8 parts by weight, the methyl hydroxybenzoate of 0.2 parts by weight of part
With the ethyl hydroxy benzoate of 0.1 parts by weight；And 0.3 parts by weight hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers,
Acrylic acid (ester) class of 0.2 parts by weight/C10-30 alkylol acrylamide acid esters cross-linked polymer, 0.03 parts by weight EDETATE SODIUM and
56.81 the deionized water of parts by weight.
Each auxiliary material in face cream I cosmetic base is separately heated to 75 DEG C, is mixed evenly, is placed in emulsifying
Emulsify, insulated and stirred 20 minutes, cool in device.Active component, and the ammonia of 0.12 parts by weight are added when temperature is down to 43 DEG C
Methylpropanol, the Phenoxyethanol of 0.5 parts by weight, the essence of 0.1 parts by weight, stir, and obtain face cream I.
Embodiment 2
Cosmetic additive agent II preparation：
(1) by the jellyfish of 1 parts by weight to drain away the water, it is dipped in deionized water and soaks, the weight of the deionized water is
3 times of jellyfish weight, a deionized water was changed at interval of 1 hour, soaks 10 times, sloughs the salinity (sodium chloride) entrained by jellyfish
And drain away the water.
(2) by jellyfish after desalting processing at normal temperatures with 2mol/L potassium hydroxide solution under 0.35MPa pressure room
Warm water solution, the weight of the potassium hydroxide solution are 3 times of jellyfish weight, and hydrolysis leaches alkaline viscous fluid after 1 hour, uses again
Weight hydrolyzes for 3 times of potassium hydroxide solution of jellyfish weight, is hydrolyzed 3 times using 2mol/L potassium hydroxide solution altogether.
(3) and then with 2mol/L hydrochloric acid solution continue to hydrolyze, the amount of the hydrochloric acid solution is 3 times of jellyfish weight, water
Solution leaches acid viscous fluid after 1 hour, is hydrolyzed again with 3 times of the hydrochloric acid solution that weight is jellyfish weight, altogether using 2mol/L
Hydrochloric acid solution hydrolyze 3 times.
(4) collect that 3 potassium hydroxide solutions hydrolyze obtained alkaline viscous fluid and 3 hydrochloric acid solutions hydrolyze obtained acidity
Viscous fluid, homogeneous, centrifugal treating, obtain alkaline clear liquid and acid clear liquid, by resulting alkaline clear liquid and acid clear liquid respectively
Merge, obtain mixing clear liquid, filtered after the mixing clear liquid is concentrated into 20 parts by weight, add appropriate preservative Phenoxyethanol and produce
To jellyfish extract II；
(5) by the carbohydrate isomer of the jellyfish extract II of 5 resulting parts by weight and 6 parts by weight
(Pentavitin) mix, obtain cosmetic additive agent II.
Face cream II preparation：
Active component：By 6 parts by weight in the cosmetic additive agent II of 1 parts by weight and face cream II cosmetic base
Butanediol, the glycerine of 5 parts by weight, the Sodium Hyaluronate of 0.03 parts by weight are well mixed, as water miscible active component；Will shield
The tocopherol acetate of 0.5 part of weight in skin frost II cosmetic base is as oil-soluble active component.
Auxiliary material in face cream II cosmetic base：The spiny dogfish of the cyclomethicone of 7 parts by weight, 5 parts by weight
Alkane, the carbonic acid dioctyl ester of 3 parts by weight, the octyl group polymethyl siloxane of 2.5 parts by weight, the cetostearyl alcohol olive of 2.0 parts by weight
The smooth olive oleate of oleate/sorb, the methyl hydroxybenzoate of 0.2 parts by weight and the ethyl hydroxy benzoate of 0.1 parts by weight；And 0.3 weight
Part hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, the allantoin and 0.03 parts by weight of 0.3 parts by weight
The deionized water of EDETATE SODIUM and 66.49 parts by weight.
Each auxiliary material in face cream II cosmetic base is separately heated to 75 DEG C, is mixed evenly, is placed in emulsification
It is fully emulsified in device, insulated and stirred 20 minutes, cooling.Add active component when temperature is down to 43 DEG C, and 0.5 parts by weight
The essence of Phenoxyethanol, 0.05 parts by weight, stirs, and obtains face cream II.
Embodiment 3
Cosmetic additive agent III preparation：
(1) jellyfish of 8 parts by weight to drain away the water is dipped in deionized water and soaked, the weight of the deionized water is water
3 times of female weight, at interval of a deionized water is changed within 1 hour, soak 10 times, slough salinity (sodium chloride) entrained by jellyfish simultaneously
Drain away the water.
(2) by jellyfish after desalting processing at normal temperatures with 2mol/L potassium hydroxide solution under 0.4MPa pressure room temperature
Hydrolysis, the weight of the potassium hydroxide solution are 5 times of jellyfish weight, and hydrolysis leaches alkaline viscous fluid after 1.2 hours, uses again
Weight hydrolyzes for 5 times of potassium hydroxide solution of jellyfish weight, is hydrolyzed 3 times using 2mol/L potassium hydroxide solution altogether.
(3) and then with 2mol/L hydrochloric acid solution continue to hydrolyze, the amount of the hydrochloric acid solution is 5 times of jellyfish weight, water
Solution leaches acid viscous fluid after 1 hour, is hydrolyzed again with 5 times of the hydrochloric acid solution that weight is jellyfish weight, altogether using 2mol/L
Hydrochloric acid solution hydrolyze 3 times.
(4) collect that 3 potassium hydroxide solutions hydrolyze obtained alkaline viscous fluid and 3 hydrochloric acid solutions hydrolyze obtained acidity
Viscous fluid, homogeneous, centrifugal treating, obtain alkaline clear liquid and acid clear liquid, by resulting alkaline clear liquid and acid clear liquid respectively
Merge, obtain mixing clear liquid, filtered after the mixing clear liquid is concentrated into 30 parts by weight, add appropriate preservative Phenoxyethanol and produce
To jellyfish extract II I；
(5) by the resulting jellyfish extract II I of 8 parts by weight and the carbohydrate isomer of 1 parts by weight
(Pentavitin) mix, obtain cosmetic additive agent III.
Moisturizing lotion I preparation：
Active component：By 5 weights in the cosmetic additive agent III of 0.05 parts by weight and moisturizing lotion I cosmetic base
The butanediol of part, the glycerine of 8 parts by weight, the Sodium Hyaluronate of 0.04 parts by weight, the trimethylglycine of 1 parts by weight is measured to mix
It is even, as water miscible active component；By the Butyrospermum parkii fruit fat and 0.5 of 2 parts by weight in moisturizing lotion I cosmetic base
The tocopherol acetate of parts by weight is well mixed, as oil-soluble active component.
Auxiliary material in moisturizing lotion I cosmetic base：The palm of the cyclomethicone of 5 parts by weight, 3 parts by weight
Sour ethylhexyl, the Nexbase 2004 of 2 parts by weight, the jojoba oil of 2 parts by weight, the dimethyl silicone polymer of 2 parts by weight, 2 weights
Measure the methyl of polyglycereol -3 distearate of part, the stearine of 1 parts by weight, 0.2 parts by weight methyl hydroxybenzoate and
The ethyl hydroxy benzoate of 0.1 parts by weight；And 0.3 parts by weight hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers,
The deionized water of the EDETATE SODIUM and 64.93 parts by weight of the allantoin of 0.2 parts by weight and 0.03 parts by weight.
Each auxiliary material in moisturizing lotion I cosmetic base is separately heated to 75 DEG C, is mixed evenly, is placed in emulsification
Emulsify, insulated and stirred 20 minutes, cool in device.Active component, and the benzene oxygen of 0.5 parts by weight are added when temperature is down to 43 DEG C
The essence of ethanol, 0.15 parts by weight, stirs, and obtains moisturizing lotion I.
Embodiment 4
Cosmetic additive agent IV preparation：
(1) by the jellyfish of 12 parts by weight to drain away the water, it is dipped in deionized water and soaks, the weight of the deionized water is
3 times of jellyfish weight, a deionized water was changed at interval of 1 hour, soaks 10 times, sloughs the salinity (sodium chloride) entrained by jellyfish
And drain away the water.
(2) by jellyfish after desalting processing at normal temperatures with 2mol/L potassium hydroxide solution under 0.4MPa pressure room temperature
Hydrolysis, the weight of the potassium hydroxide solution are 4 times of jellyfish weight, and hydrolysis leaches alkaline viscous fluid after 1 hour, again with weight
4 times of the potassium hydroxide solution hydrolysis for jellyfish weight is measured, is hydrolyzed 3 times using 2mol/L potassium hydroxide solution altogether.
(3) and then with 2mol/L hydrochloric acid solution continue to hydrolyze, the amount of the hydrochloric acid solution is 4 times of jellyfish weight, water
Solution leaches acid viscous fluid after 1 hour, is hydrolyzed again with 4 times of the hydrochloric acid solution that weight is jellyfish weight, altogether using 2mol/L
Hydrochloric acid solution hydrolyze 3 times.
(4) collect that 3 potassium hydroxide solutions hydrolyze obtained alkaline viscous fluid and 3 hydrochloric acid solutions hydrolyze obtained acidity
Viscous fluid, homogeneous, centrifugal treating, obtain alkaline clear liquid and acid clear liquid, by resulting alkaline clear liquid and acid clear liquid respectively
Merge, obtain mixing clear liquid, filtered after the mixing clear liquid is concentrated into 12 parts by weight, add appropriate preservative Phenoxyethanol i.e.
Obtain jellyfish extract I V；
(5) by the resulting jellyfish extract I V of 1.5 parts by weight and the carbohydrate isomer of 8 parts by weight
(Pentavitin) mix, obtain cosmetic additive agent IV.
Moisturizing astringent I preparation：
Active component：By 6 weight in the cosmetic additive agent IV of 3 parts by weight and moisturizing astringent I cosmetic base
The trimethylglycine mixing of the butanediol of part, the Sodium Hyaluronate of 0.02 parts by weight, 1.5 parts by weight, as water miscible work
Property component.
Auxiliary material in moisturizing astringent I cosmetic base：Double-PEG-18 methyl ethers dimethylsilanes of 1.5 parts by weight,
The AVC of 0.1 parts by weight, the propane diols of 5 parts by weight, the PEG/PPG- of 1.5 parts by weight
17/6 copolymer, the glycerin polyether -26 of 1 parts by weight, the ethanol of 5 parts by weight, the methyl hydroxybenzoate of 0.1 parts by weight, 0.03 parts by weight
Ethyl hydroxy benzoate, the EDETATE SODIUM of 0.05 parts by weight, and the deionized water of 74.6 parts by weight.
Each auxiliary material in moisturizing astringent I cosmetic base is mixed and stirred for uniformly, to be heated to 75 DEG C, insulated and stirred
20 minutes, cooling.When temperature is down to 43 DEG C, active component, the Phenoxyethanol of 0.5 parts by weight and 0.1 parts by weight are added
Essence, stir, obtain moisturizing astringent I.
Embodiment 5
Cosmetic additive agent V preparation：
(1) by the jellyfish of 15 parts by weight to drain away the water, it is dipped in deionized water and soaks, the weight of the deionized water is
3 times of jellyfish weight, a deionized water was changed at interval of 1 hour, soaks 10 times, sloughs the salinity (sodium chloride) entrained by jellyfish
And drain away the water.
(2) by jellyfish after desalting processing at normal temperatures with 2mol/L potassium hydroxide solution under 0.3MPa pressure room temperature
Hydrolysis, the weight of the potassium hydroxide solution are 5 times of jellyfish weight, and hydrolysis leaches alkaline viscous fluid after 1 hour, again with weight
5 times of the potassium hydroxide solution hydrolysis for jellyfish weight is measured, is hydrolyzed 3 times using 2mol/L potassium hydroxide solution altogether.
(3) and then with 2mol/L hydrochloric acid solution continue to hydrolyze, the amount of the hydrochloric acid solution is 5 times of jellyfish weight, water
Solution leaches acid viscous fluid after 1 hour, is hydrolyzed again with 5 times of the hydrochloric acid solution that weight is jellyfish weight, altogether using 2mol/L
Hydrochloric acid solution hydrolyze 3 times.
(4) collect that 3 potassium hydroxide solutions hydrolyze obtained alkaline viscous fluid and 3 hydrochloric acid solutions hydrolyze obtained acidity
Viscous fluid, homogeneous, centrifugal treating, obtain alkaline clear liquid and acid clear liquid, by resulting alkaline clear liquid and acid clear liquid respectively
Merge, obtain mixing clear liquid, filtered after the mixing clear liquid is concentrated into 45 parts by weight, add appropriate preservative Phenoxyethanol and produce
To jellyfish extract V；
(5) by the resulting jellyfish extract V of 6 parts by weight and the carbohydrate isomer of 3 parts by weight
(Pentavitin) mix, obtain cosmetic additive agent V.
Moisturizing eye essence I preparation：
Active component：By 5 weights in the cosmetic additive agent V of 0.6 parts by weight and moisturizing eye essence I cosmetic base
The Sodium Hyaluronate mixing of the butanediol, 0.03 parts by weight of part is measured, as water miscible active component；By moisturizing eye essence I
Cosmetic base in 0.5 parts by weight tocopherol acetate as oil-soluble active component.
Auxiliary material in moisturizing eye essence I cosmetic base：The cyclomethicone of 7 parts by weight, 3 parts by weight
Octyl group polymethyl siloxane, the carbonic acid dioctyl ester of 2 parts by weight, two C12-13 alcohol malates of 0.5 parts by weight, 0.2 parts by weight
Methyl hydroxybenzoate and 0.1 parts by weight ethyl hydroxy benzoate；And 1.0 ammonium acryloyldime-thyltaurate/docosyl alcohols of parts by weight gather
The Methacrylate Crosspolymer of ether -25, the allantoin of 0.2 parts by weight, the glycerine of 5 parts by weight, the EDTA of 0.05 parts by weight
The deionized water of disodium and 74.27 parts by weight.
Each auxiliary material in moisturizing eye essence I cosmetic base is mixed evenly, is heated to 75 DEG C, insulated and stirred
20 minutes, cooling.When temperature is down to 43 DEG C, active component, and the Phenoxyethanol of 0.5 parts by weight, 0.05 parts by weight are added
Essence, stir, obtain moisturizing eye essence I.
Embodiment 6
Cosmetic additive agent VI preparation：
(1) by the jellyfish of 18 parts by weight to drain away the water, it is dipped in deionized water and soaks, the weight of the deionized water is
3 times of jellyfish weight, a deionized water was changed at interval of 1 hour, soaks 10 times, sloughs the salinity (sodium chloride) entrained by jellyfish
And drain away the water.
(2) by jellyfish after desalting processing at normal temperatures with 2mol/L potassium hydroxide solution under 0.3MPa pressure room temperature
Hydrolysis, the weight of the potassium hydroxide solution are 4 times of jellyfish weight, and hydrolysis leaches viscous fluid after 1 hour, is with weight again
4 times of the potassium hydroxide solution hydrolysis of jellyfish weight, is hydrolyzed 3 times using 2mol/L potassium hydroxide solution altogether.
(3) and then with 2mol/L hydrochloric acid solution continue to hydrolyze, the amount of the hydrochloric acid solution is 4 times of jellyfish weight, water
Solution leaches viscous fluid after 1 hour, is hydrolyzed again with 4 times of the hydrochloric acid solution that weight is jellyfish weight, altogether using 2mol/L salt
Aqueous acid hydrolysis 3 times.
(4) collect that 3 potassium hydroxide solutions hydrolyze obtained viscous fluid and 3 hydrochloric acid solutions hydrolyze obtained viscous fluid,
Homogeneous, centrifugal treating respectively, obtain clear liquid, and resulting clear liquid is merged, and are filtered after concentrating 35 parts by weight, add appropriate anti-corrosion
Agent Phenoxyethanol obtains jellyfish extract VI；
(5) by the resulting jellyfish extract VI of 10 parts by weight and the carbohydrate isomer of 2.5 parts by weight
(Pentavitin) mix, obtain cosmetic additive agent VI.
Gel miles of I of clean skin preparation：
Active component：By 5 parts by weight in the cosmetic additive agent VI of 8 parts by weight and Gel miles of I of clean skin cosmetic base
Butanediol, the Sodium Hyaluronate of 0.03 parts by weight be well mixed, as water miscible active component；By Gel miles of I of clean skin change
The lauroylamidopropyl betaine of 8 parts by weight in cosmetic matrix, the sodium lauroyl glutamate of 5 parts by weight, the coconut palm of 2.5 parts by weight
Seed oil diglycollic amide (coconut oleoyl amine DEA), the olive oil PEG-7 esters of 3 parts by weight, the methoxy cinnamic acid of 0.1 parts by weight
Ethylhexyl, the butylmethoxydibenzoylmethane of 0.05 parts by weight are well mixed, as oil-soluble active component.
Auxiliary material in Gel miles of I of clean skin cosmetic base：Acrylic acid (ester) class/C10-30 alkylol acrylamides of 2.5 parts by weight
The deionized water of acid esters cross-linked polymer, the EDETATE SODIUM of 0.05 parts by weight and 65.27 parts by weight.
Each auxiliary material in Gel miles of I of clean skin cosmetic base is mixed evenly, is heated to 75 DEG C, insulated and stirred 20 is divided
Clock, cooling.When temperature is down to 65 DEG C, oil-soluble active component is added, is stirred, vacuum outgas；When temperature is down to 43 DEG C,
Phenoxyethanol, the essence of 0.2 parts by weight of water miscible active component and 0.5 parts by weight are added, stirs, obtains clean skin
Gel miles of I.
Comparative example 1
Remove jellyfish extract, carbohydrate isomer in the active component for preparing face cream I of embodiment 1
(Pentavitin), remaining obtains face cream III with embodiment 1, and according to the preparation method of embodiment 1.
Comparative example 2
Remove jellyfish extract and carbohydrate isomer in the active component for preparing face cream II of embodiment 2
(Pentavitin), remaining obtains face cream IV with embodiment 2, and according to the preparation method of embodiment 2.
Comparative example 3
Remove jellyfish extract and carbohydrate isomer in the active component for preparing moisturizing lotion I of embodiment 3
(Pentavitin), remaining obtains moisturizing lotion II with embodiment 3, and according to the preparation method of embodiment 3.
Comparative example 4
Remove jellyfish extract and carbohydrate isomer in the active component for preparing moisturizing astringent I of embodiment 4
(Pentavitin), remaining obtains moisturizing astringent II with embodiment 4, and according to the preparation method of embodiment 4.
Comparative example 5
Remove jellyfish extract and carbohydrate isomerism in the preparation moisturizing eye essence I of embodiment 5 active component
Body (Pentavitin), remaining obtains moisturizing eye essence II with embodiment 5, and according to the preparation method of embodiment 5.
Comparative example 6
Remove jellyfish extract and carbohydrate isomer in Gel miles of I of preparation clean skin of embodiment 6 active component
(Pentavitin), remaining obtains Gel miles of II of clean skin with embodiment 6, and according to the preparation method of embodiment 6.
Using effect is tested：
The skin-protection product obtained to embodiment 1-6 carries out using effect test with the obtained skin-protection products of comparative example 1-6.With
Exemplified by the face cream I of the embodiment 1 and face cream III of comparative example 1.Carried out with the 19 entitled object of female volunteers of 20~35 years old
Assess test, wherein more than 30 years old 3,20~30 years old 16.Choose the symmetrical two region conducts of Medial upper arm of volunteer
Test zone, one of region use the face cream of comparative example 1 using the face cream I prepared by embodiment 1, another region
III, the two is tested in the environment in constant temperature and humidity (22 DEG C of temperature, humidity 55%), and test event is human body skin water
Divide content measuring and percutaneous water loss test.Human body skin moisture test period was 3.5 hours, at interval of 0.5 hour
Test is once；The cycle of percutaneous water loss test is 3.5 hours, at interval of test in 0.5 hour once.
Human body skin moisture is tested：
Tested using capacitance method principle, moisture measurement probe vertical is pressed in tested skin surface, probe top
A segment distance is pushed back, probe is internal to have a spring to make to keep 0.16N pressure to be pressed in skin surface 1 second at the top of probe, measures
Humidity measurements (Moisture Measurement Value, MMV).The humidity measurements are between 0~150.
The skin of Medial upper arm is cleaned, volunteer sits quietly 0.5 in the environment of constant temperature and humidity (22 DEG C of temperature, humidity 55%)
After hour, the initial humidity that two test zones are carried out using skinanalysis apparatus (German CK, Cutometer MPA580) is measured
The measurement of value.After 0.5 hour, then smear face cream I and comparative example prepared by the embodiment 1 of equivalent in two test zones respectively
The 1 face cream III prepared, and test the humidity measurements in two regions, interval time is respectively 0.5 hour, 1 hour, it is 1.5 small
When, 2 hours, 2.5 hours, 3 hours, 3.5 hours.Measure humidity measurements.
Each test data is subtracted into the change that initial humidity measured value is the period humidity measurements, then divided by initially
Humidity measurements draw skin moisture content growth rate, as shown in Table 1 and Table 2.
The calculation formula of skin moisture content growth rate is：
Skin moisture content growth rate %=(MMVt-MMV0)/MMV0× 100%
Wherein：MMV0：The initial humidity measured value of skin before smearing；
MMVt：T period humidity of skin measured value after smearing.
Table 1
Table 2
According to the data of Tables 1 and 2, obtain embodiment 1 face cream I and comparative example 1 face cream III it is aqueous in skin
The contrast curve that skin moisture content growth rate changes in examination is measured, as shown in Figure 1.
It can be drawn by table 1, table 2 and Fig. 1：All in all, in minute, the face cream I that is prepared using embodiment 1
The moisture growth rate of face cream III than being prepared using comparative example 1 is higher；In longer time interval, implementation is used
Face cream I prepared by example 1 test zone still has higher moisture.
In addition, according to above-mentioned human body skin moisture method of testing, the face cream II prepared by embodiment 2 and right is used
Face cream IV prepared by ratio 2 determines the change of skin moisture content growth rate；Using the moisturizing lotion I prepared by embodiment 3 and
Moisturizing lotion II measure skin moisture content growth rate changes prepared by comparative example 3；Use the moisturizing prepared by embodiment 4
Adornment water I and the moisturizing astringent II measure skin moisture content growth rate changes prepared by comparative example 4；It is made using embodiment 5
Standby moisturizing eye essence I and the moisturizing eye essence II measure skin moisture content growth rate changes prepared by comparative example 5；Make
Facial cleansing is carried out with Gel miles of I of clean skin prepared by embodiment 6 and Gel miles of II of clean skin prepared by comparative example 6, determines skin water
Divide the change of content growth rate.
Comparing result can be drawn：Using the cosmetics of the cosmetic additive agent containing the present invention, even in relative humidity
In relatively low environment, remaining able to enduringly pin the moisture of skin, skin can keep more water content for a long time, so as to
Make skin water profit plentiful.
The percutaneous water loss of skin (TEWL) is tested：
By taking the face cream I of embodiment 1 and the face cream III of comparative example 1 as an example.Using standard measure, during average computation
Between be 60 seconds.
Test philosophy is Fick (Fick) diffusion law dm/dt=-DAdp/dx
Wherein, A：Area (m2) m：The diffusing capacity (g) of moisture
t：Time (h) D：Diffusion constant (0.0877g/mgmmHg)
p：Steam pressure (mmHg) x：The distance (m) of skin surface detection point
Measuring probe is made up of two groups of temperature sensors and humidity sensor, and probe parameter is：Cylinder diameter φ
=10mm, cylinder height H=20mm.
The shapes and sizes of measuring probe can prevent influence of the air flow to measurement data, and carry out school to probe
It is accurate.
The skin of Medial upper arm is cleaned, volunteer sits quietly 0.5 in the environment of constant temperature and humidity (22 DEG C of temperature, humidity 55%)
After hour, symmetrical two regions of Medial upper arm are chosen as test zone, smear skin care prepared by the embodiment 1 of equivalent respectively
Face cream III prepared by white I and comparative example 1, tests the percutaneous water loss in two regions, interval time is respectively 0.5 hour,
1 hour, 1.5 hours, 2 hours, 2.5 hours, 3 hours, 3.5 hours.Percutaneous water loss rate is measured, as shown in Table 3 and Table 4.
Table 3
Table 4
According to the data shown in table 3 and table 4, the face cream I of embodiment 1 and the face cream III of comparative example 1 are obtained in skin
The contrast curve of percutaneous water loss change in water content test, as shown in Figure 2.
Can be drawn by table 3, table 4 and Fig. 2, in minute, the face cream I that is prepared using embodiment 1 through the severe edema due to hypofunction of the spleen
Point turnover rate has more preferable water lock apparently higher than the face cream III prepared using comparative example 1, face cream I prepared by embodiment 1
Effect；Skin water lock ability directly affects the percutaneous water loss of skin, only has preferable water lock water holding capacity in skin
When, the percutaneous water loss of skin could be reduced.
In addition, the method for testing according to above-mentioned percutaneous water loss, uses the face cream II prepared by embodiment 2 and contrast
Face cream IV prepared by example 2 determines percutaneous water loss rate change；Use the moisturizing lotion I and comparative example 3 prepared by embodiment 3
Prepared moisturizing lotion II determines percutaneous water loss rate change；Use the moisturizing astringent I prepared by embodiment 4 and contrast
Moisturizing astringent II prepared by example 4 determines percutaneous water loss rate change；Use the moisturizing eye essence prepared by embodiment 5
The I and moisturizing eye essence II prepared by comparative example 5 determines percutaneous water loss rate change；Using clean prepared by embodiment 6
Gel miles of I of skin and Gel miles of II of clean skin prepared by comparative example 6 carry out facial cleansing, determine percutaneous water loss rate change.
As can be seen from the results：Using containing the present invention cosmetic additive agent cosmetics, even in relative humidity compared with
In low environment, remain able to reduce percutaneous water loss, make skin more water profit health.
Claims (15)
1. a kind of preparation method of cosmetic additive agent, it is characterised in that comprise the following steps：
1) by after jellyfish desalting processing, processing is hydrolyzed using acidic hydrolysis agent and basic hydrolysis agent, obtains acid viscous fluid
With alkaline viscous fluid；
2) the acid viscous fluid and the alkaline viscous fluid are subjected to separating treatment respectively, obtain acid clear liquid and alkalescence is clear
Liquid, the acid clear liquid and the alkaline clear liquid are merged, obtain mixing clear liquid；
3) impurity will be removed after the mixing clear liquid concentration, obtains jellyfish extract；
4) the jellyfish extract is mixed with carbohydrate isomer Pentavitin, obtains cosmetic additive agent, the water
The weight ratio of female extract and carbohydrate isomer is 1-20：0.001-10；
The desalting processing includes：Jellyfish is placed in immersion treatment in deionized water；
The acidic hydrolysis agent is hydrochloric acid solution, sulfuric acid solution, salpeter solution；The basic hydrolysis agent be potassium hydroxide solution,
Sodium hydroxide solution, calcium hydroxide suspension.
2. the preparation method of cosmetic additive agent according to claim 1, it is characterised in that the water of every 1 parts by weight
Mother adds the deionized water of 2-6 parts by weight.
3. the preparation method of cosmetic additive agent according to claim 2, it is characterised in that the water of every 1 parts by weight
Mother adds the deionized water of 3-5 parts by weight.
4. the preparation method of the cosmetic additive agent according to claim any one of 1-3, it is characterised in that at the immersion
The treatment conditions of reason are：Soak at room temperature, change a deionized water at interval of 0.5-4 hours, immersion number is 3-15 times.
5. the preparation method of cosmetic additive agent according to claim 4, it is characterised in that the processing of the immersion treatment
Condition is：Soak at room temperature, change a deionized water at interval of 1-2 hours, immersion number is 6-10 times.
6. the preparation method of the cosmetic additive agent according to any one of claim 1-3, it is characterised in that the hydrolysis
The treatment conditions of processing are：The jellyfish of every 1 parts by weight adds the acidic hydrolysis agent of 3-6 parts by weight and the alkaline water of 3-6 parts by weight
Agent is solved, under 0.1-0.6MPa pressure, Hydrolysis At Room Temperature 0.5-2 hours, is hydrolyzed 2-6 times.
7. the preparation method of cosmetic additive agent according to claim 6, it is characterised in that the processing of the hydrolysis process
Condition is：The jellyfish of every 1 parts by weight adds the acidic hydrolysis agent of 3-6 parts by weight and the basic hydrolysis agent of 3-6 parts by weight, in 0.3-
Under 0.5MPa pressure, Hydrolysis At Room Temperature 0.8-1.2 hours, hydrolyze 3-5 times.
8. the preparation method of the cosmetic additive agent according to any one of claim 1-3, it is characterised in that the acidity
Hydrolytic reagent and the concentration of basic hydrolysis agent are 1-5mol/L.
9. the preparation method of cosmetic additive agent according to claim 8, it is characterised in that the acidic hydrolysis agent and alkali
The concentration of property hydrolytic reagent is 1.5-2.5mol/L.
10. the preparation method of the cosmetic additive agent according to any one of claim 1-3, it is characterised in that the water
Solution processing hydrolyzes first to be hydrolyzed with basic hydrolysis agent, then with acidic hydrolysis agent；Or first hydrolyzed with acidic hydrolysis agent, then with alkaline
Hydrolytic reagent hydrolyzes.
11. the preparation method of the cosmetic additive agent according to any one of claim 1-3, it is characterised in that describedization
In cosmetic additive, the weight ratio of the jellyfish extract and carbohydrate isomer is 3-15：0.05-8.
12. a kind of cosmetic additive agent, it passes through the preparation side of the cosmetic additive agent any one of claim 1-11
Method is prepared.
A kind of 13. cosmetics of the cosmetic additive agent comprising described in claim 12, it is characterised in that including：
The cosmetic base of 70-98.999 parts by weight,
The cosmetic additive agent of 1.001-30 parts by weight；
Based on the gross weight of the cosmetics, the addition of the carbohydrate isomer in the cosmetic additive agent is
0.001-10 parts by weight, the addition of the jellyfish extract in the cosmetic additive agent is 1-20 parts by weight.
14. cosmetics according to claim 13, it is characterised in that the gross weight based on the cosmetics, the cosmetic
The addition of the carbohydrate isomer in product additive is 0.05-8 parts by weight, described in the cosmetic additive agent
The addition of jellyfish extract is 3-15 parts by weight.
15. the cosmetics according to claim 13 or 14, it is characterised in that the cosmetic base is skin care cream, profit
Skin emulsion, moisture retention water, facial treatment essence, mildy wash or eye essence.
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| CN108245457A (en) * | 2018-03-27 | 2018-07-06 | 广州禾力生物科技有限公司 | A kind of antiallergic composition and preparation method and application |
| CN109770275A (en) * | 2019-02-22 | 2019-05-21 | 水母娘娘海洋生物科技有限公司 | A kind of aurelia water and its preparation method and application |
| CN113546030A (en) * | 2021-08-12 | 2021-10-26 | 杭州满天颂生物科技有限公司 | Moisturizing additive, preparation method thereof and cosmetic product thereof |
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| CN104546532B (en) * | 2015-01-28 | 2017-07-18 | 广州丽丰化妆品制造有限公司 | Essence containing chitosan oligomer and jellyfish collagen albumen and its facial mask being made |
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Effective date of registration: 20210531 Address after: No.23 Xianke Er Road, Huadong Town, Huadu District, Guangzhou City, Guangdong Province 510800 Patentee after: GUANGZHOU KENENG COSMETIC RESEARCH Co.,Ltd. Patentee after: GUANGDONG DANZ GROUP Co.,Ltd. Address before: No.23, Xianke 2nd Road, Huadong Town, Huadu District, Guangzhou, Guangdong 510000 Patentee before: GUANGZHOU KENENG COSMETIC RESEARCH Co.,Ltd. Patentee before: GUANGZHOU BAIYUN LIANJIA FINE CHEMICAL FACTORY Patentee before: GUANGDONG DANZ GROUP Co.,Ltd. |