CN105455131A - Formula of garlic oil and sea buckthorn oil containing soft capsules and preparation process - Google Patents

Formula of garlic oil and sea buckthorn oil containing soft capsules and preparation process Download PDF

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Publication number
CN105455131A
CN105455131A CN201510882580.6A CN201510882580A CN105455131A CN 105455131 A CN105455131 A CN 105455131A CN 201510882580 A CN201510882580 A CN 201510882580A CN 105455131 A CN105455131 A CN 105455131A
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China
Prior art keywords
capsule
oil
garlic
pill
gelatin
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CN201510882580.6A
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Chinese (zh)
Inventor
吴树弟
方祎
杨小宏
张静
胡荣国
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SHAANXI CENTURY HEALTH PHARMACY Co Ltd
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SHAANXI CENTURY HEALTH PHARMACY Co Ltd
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Priority to CN201510882580.6A priority Critical patent/CN105455131A/en
Publication of CN105455131A publication Critical patent/CN105455131A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a formula of a health-care product, namely, garlic oil and sea buckthorn oil containing soft capsules, and a preparation process. The garlic oil and sea buckthorn oil containing soft capsules are obtained through research on the basis of existing sea buckthorn oil type soft capsule health care food. According to the formula, the soft capsules are prepared from 20-100 parts of garlic oil, 50-500 parts of sea buckthorn oil, 200-800 parts of corn oil, 100-200 parts of gelatin, 50-100 parts of glycerin, 100-200 parts of purified water, 1-2 parts of titanium dioxide and 0.5-5 parts of radish red through processes of burdening, drying, pressing and the like and have the efficacy of boosting the immunity and the like.

Description

A kind of formula of garlic Seabuckthorn Oil soft capsule and preparation technology
Technical field
The present invention relates to a kind of formula and preparation technology of health food, specifically a kind of formula of garlic Seabuckthorn Oil soft capsule and preparation technology.
Background technology
Immunity is that human body is resisted extraneous virulence factor and maintained the ability of homoiostasis, and namely human immune system carries out a kind of ability of self-protection, with the normal development sustained life and health.Modern society, sub-health state is very general, being at all of various disease reason---hypoimmunity.Cause the reason of hypoimmunity to have many, comprise environmental pollution, food pollution, operating pressure, economic pressures, improper diet etc.The energy of the healthy body full of physical strength is the capital that people adapt to modern society's competition, however every day anxiety working and learning body can be made to be in overdraw state, as can not get having a rest timely and adjust, accumulating over a long period, immunity of organisms will be caused low.
In " Chinese international inferior health academy's successes in 2002 seminar " held in April, 2002, expert points out: China has the people of 70% to be in sub-health state at present, and the people of 15% is in morbid state, only has the people of 15% to be in health status." white collar " is the main population of inferior health, and has the people of more than 85% to be in sub-health state in company manager.How to improve immunity and become the topic that people often talk about, become the focus of growing interest, developing with develop immunitypty is that the health food of health care just has vast social effect, and has huge market potential.
Now commercially there is the product of many develop immunitypty, as several large classes such as lucidum spore powder, American Ginseng, protein, vitamin, propolis, spirulinas.But it is expensive that these products have, some processed complexs, need to invent some cheap new products.
Summary of the invention
The object of the invention is the kind of inventing a kind of new develop immunitypty---have more curative effect and stay-in-grade garlic Seabuckthorn Oil soft capsule, and preparation technology.
The object of the invention is to be realized by following technical scheme:
Garlic Seabuckthorn Oil soft capsule, its composition of raw materials is:
Garlic oil, hippophae rhamnoides fruit oil, corn oil, gelatin, glycerine, purified water, titanium dioxide and radish red.
The mass parts of described garlic Seabuckthorn Oil soft capsule composition of raw materials is:
Garlic oil 20-100 part, hippophae rhamnoides fruit oil 50-500 part, corn oil 200-800 part, gelatin 100-200 part, glycerine 50-100 part, purified water 100-200 part, titanium dioxide 1-2 part, radish red 0.5-5 part.
Garlic Seabuckthorn Oil soft capsule preparation technology is:
Step 1. gets garlic oil, hippophae rhamnoides fruit oil, corn oil, stirs, standing, degassed, crosses screen cloth discharging, obtains capsule-core feed liquid, for subsequent use.
Step 2. purified water heats, and joins in purified water, seals, stir and heat, make it to become uniform glue by gelatin, glycerine, titanium dioxide, radish red, stops stirring, and leaves standstill and vacuumizes, degassed, obtains capsule hide glue gelatin, for subsequent use.
The capsule-core feed liquid prepared is transported in the stock chest of encapsulating machine by step 3., is transported in the storage glue groove of encapsulating machine by the capsule hide glue gelatin prepared, starts encapsulating machine, suppress to obtain capsule and pill.
The capsule and pill heat treatment that step 4. suppresses, makes it lower the temperature and the surperficial moisture that leaves, obtains sizing capsule and pill.
Capsule and pill after step 5. sizing washs with 95% edible alcohol.
Take out after the washed capsule and pill of step 6. puts into hothouse inner drying.
Preferably, step 1 is: get garlic oil, hippophae rhamnoides fruit oil, corn oil, stir, and leaves standstill and vacuumizes, vacuum-0.06MPa ~-0.08Mpa, degassed 1 hour, crosses 80 eye mesh screen dischargings, obtains capsule-core feed liquid.
Preferably, step 2 is: when purified water is heated to 60 DEG C, joins in purified water, seal gelatin, glycerine, titanium dioxide, radish red, stir, and be heated to 70 DEG C, stir and make it to become uniform glue, stop stirring, leave standstill and vacuumize, vacuum-0.06 ~-0.08MPa, degassed 1 hour, obtains capsule hide glue gelatin.
Preferably, step 3 is: temperature 18 ~ 26 DEG C, and the condition of relative humidity 40 ~ 50% presses down obtained capsule and pill, controls the heavy 1.0g of every capsule-core feed liquid.
Preferably, step 6 is: washed capsule and pill is put into hothouse inner drying and taken out for 20 ~ 30 hours; The temperature of hothouse 25 ~ 30 DEG C, relative humidity 30 ~ 40%.
The present invention is the research carried out on the basis of existing Seabuckthorn Oil soft capsule, make a kind of newly, to improve formula and preparation technology that curative effect and technique prepares level than existing product.Garlic Seabuckthorn Oil soft capsule is with garlic oil, hippophae rhamnoides fruit oil for primary raw material, and with corn oil, gelatin, glycerine, purified water, titanium dioxide, radish red for auxiliary material, the health food made, has the health care of develop immunitypty.This product adopts modern preparation technique machine-shaping, and definite functions is quality controllable, takes safety.
The present invention possesses following advantage:
1. former, the auxiliary material of this product is all through inspection, and adopt Modern preparations processes to form, production technology, production environment meet food hygiene related request, and product safety is effective, can eat for a long time.
2. the selected article prescription with develop immunitypty of this product, ensure that the health care of product.Containing allicin in garlic oil.Find in the experiment that allicin affects immune function of mice, take medicine group spleen, thymus gland weight all have increase, T lymphocyte activator increases, hemolysin quantity increases, monocyte secretion level improves, lysozyme release increases, and therefore allicin can improve cellular immunity, humoral immunity and non-specific immune function.Hippophae rhamnoides fruit oil is made up of multiple beneficial aliphatic acid, and wherein unrighted acid is up to 70%, in hippophae rhamnoides fruit oil carotenoid and vitamin E and various trace elements content also higher.It is low that the full nutrition element of hippophae rhamnoides fruit oil can be applicable to immunity of organisms.
3. formulation selected by this product is reasonable, and this product primary raw material is garlic oil, hippophae rhamnoides fruit oil, is grease, should not be prepared into Conventional solid preparation, and soft capsule can solve the problem.Soft capsule dosage accurately, be easy to carry, pleasing appearance.Soft capsule dosage form has the production equipment of sizing and the manufacturer of specialty, easily realizes industrialization, large-scale production, so formulation is decided to be soft capsule by this product.
Detailed description of the invention
The present invention includes formula and the preparation technology of garlic Seabuckthorn Oil soft capsule.
One, the mass parts of garlic Seabuckthorn Oil soft capsule composition of raw materials of the present invention is:
Garlic oil 20-100 part, hippophae rhamnoides fruit oil 50-500 part, corn oil 200-800 part, gelatin 100-200 part, glycerine 50-100 part, purified water 100-200 part, titanium dioxide 1-2 part, radish red 0.5-5 part.
Two, garlic Seabuckthorn Oil soft capsule preparation technology is:
1. get garlic oil, hippophae rhamnoides fruit oil, corn oil, stir, leave standstill and vacuumize (vacuum :-0.06MPa ~-0.08Mpa) degassed 1 hour, cross 80 eye mesh screen dischargings, obtain capsule-core feed liquid, for subsequent use.
2. when purified water is heated to 60 DEG C, gelatin, glycerine, titanium dioxide, radish red are joined in purified water, seal, start paddle to stir, and be heated to 70 DEG C, stir and make it to become uniform glue, stop stirring, leave standstill and vacuumize (vacuum :-0.06 ~-0.08MPa) degassed 1 hour, obtain capsule hide glue gelatin, for subsequent use.
3. the capsule-core feed liquid prepared is transported in the stock chest of encapsulating machine, the capsule hide glue gelatin prepared is transported in the storage glue groove of encapsulating machine.Start encapsulating machine, temperature 18 ~ 26 DEG C, under the condition of relative humidity 40 ~ 50%, suppress to obtain capsule and pill, control the heavy 1.0g of every capsule-core feed liquid.
4. the capsule and pill heat treatment suppressed, makes it lower the temperature and the surperficial moisture that leaves, obtains sizing capsule and pill.
5. the capsule and pill after sizing washs with 95% edible alcohol.
6. washed capsule and pill is put into hothouse inner drying and is taken out for 20 ~ 30 hours, the temperature of hothouse 25 ~ 30 DEG C, relative humidity 30 ~ 40%.

Claims (7)

1. garlic Seabuckthorn Oil soft capsule, its composition of raw materials is:
Garlic oil, hippophae rhamnoides fruit oil, corn oil, gelatin, glycerine, purified water, titanium dioxide and radish red.
2. garlic Seabuckthorn Oil soft capsule according to claim 1, the mass parts of its composition of raw materials is:
Garlic oil 20-100 part, hippophae rhamnoides fruit oil 50-500 part, corn oil 200-800 part, gelatin 100-200 part, glycerine 50-100 part, purified water 100-200 part, titanium dioxide 1-2 part, radish red 0.5-5 part.
3. garlic Seabuckthorn Oil soft capsule preparation technology is:
Step 1. gets garlic oil, hippophae rhamnoides fruit oil, corn oil, stirs, standing, degassed, crosses screen cloth discharging, obtains capsule-core feed liquid, for subsequent use.
Step 2. purified water heats, and joins in purified water, seals, stir and heat, make it to become uniform glue by gelatin, glycerine, titanium dioxide, radish red, stops stirring, and leaves standstill and vacuumizes, degassed, obtains capsule hide glue gelatin, for subsequent use.
The capsule-core feed liquid prepared is transported in the stock chest of encapsulating machine by step 3., is transported in the storage glue groove of encapsulating machine by the capsule hide glue gelatin prepared, starts encapsulating machine, suppress to obtain capsule and pill.
The capsule and pill heat treatment that step 4. suppresses, makes it lower the temperature and the surperficial moisture that leaves, obtains sizing capsule and pill.
Capsule and pill after step 5. sizing washs with 95% edible alcohol.
Take out after the washed capsule and pill of step 6. puts into hothouse inner drying.
4. preparation technology according to claim 3, step 1 is: get garlic oil, hippophae rhamnoides fruit oil, corn oil, stir, and leaves standstill and vacuumizes, vacuum-0.06MPa ~-0.08Mpa, degassed 1 hour, crosses 80 eye mesh screen dischargings, obtains capsule-core feed liquid.
5. preparation technology according to claim 3, step 2 is: when purified water is heated to 60 DEG C, joins in purified water, seal gelatin, glycerine, titanium dioxide, radish red, stir, and be heated to 70 DEG C, stir and make it to become uniform glue, stop stirring, leave standstill and vacuumize, vacuum-0.06 ~-0.08MPa, degassed 1 hour, obtains capsule hide glue gelatin.
6. preparation technology according to claim 3, step 3 is: temperature 18 ~ 26 DEG C, and the condition of relative humidity 40 ~ 50% presses down obtained capsule and pill, controls the heavy 1.0g of every capsule-core feed liquid.
7. preparation technology according to claim 3, step 6 is: washed capsule and pill is put into hothouse inner drying and taken out for 20 ~ 30 hours; The temperature of hothouse 25 ~ 30 DEG C, relative humidity 30 ~ 40%.
CN201510882580.6A 2015-12-07 2015-12-07 Formula of garlic oil and sea buckthorn oil containing soft capsules and preparation process Pending CN105455131A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107549859A (en) * 2017-09-19 2018-01-09 太仓市林港农场专业合作社 A kind of immune soft capsule of galic essential oil compound enhancing and preparation method thereof
CN108077936A (en) * 2017-11-16 2018-05-29 山西五台山沙棘制品有限公司 A kind of Seabuckthorn Oil Spirulina soft capsule and preparation method thereof
CN111227251A (en) * 2020-03-04 2020-06-05 延寿县鼎鑫生物工程有限公司 Soft capsule containing sea-buckthorn seed oil, spirulina and vitamin E and preparation method thereof
CN112076281A (en) * 2020-10-22 2020-12-15 哈药集团技术中心 Ganoderma applanatum composition for enhancing immunity and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101496573A (en) * 2008-01-29 2009-08-05 北京康必得药业有限公司 Garlic oil soft capsule
CN102524763A (en) * 2010-12-21 2012-07-04 天津天狮生物发展有限公司 Seabuckthorn oil soft capsules and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101496573A (en) * 2008-01-29 2009-08-05 北京康必得药业有限公司 Garlic oil soft capsule
CN102524763A (en) * 2010-12-21 2012-07-04 天津天狮生物发展有限公司 Seabuckthorn oil soft capsules and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107549859A (en) * 2017-09-19 2018-01-09 太仓市林港农场专业合作社 A kind of immune soft capsule of galic essential oil compound enhancing and preparation method thereof
CN107549859B (en) * 2017-09-19 2019-11-01 太仓市林港农场专业合作社 A kind of galic essential oil compound enhances immune soft capsule and preparation method thereof
CN108077936A (en) * 2017-11-16 2018-05-29 山西五台山沙棘制品有限公司 A kind of Seabuckthorn Oil Spirulina soft capsule and preparation method thereof
CN111227251A (en) * 2020-03-04 2020-06-05 延寿县鼎鑫生物工程有限公司 Soft capsule containing sea-buckthorn seed oil, spirulina and vitamin E and preparation method thereof
CN112076281A (en) * 2020-10-22 2020-12-15 哈药集团技术中心 Ganoderma applanatum composition for enhancing immunity and preparation method thereof

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