CN106562422A - Preparation technology of ganoderma lucidum spore oil and lycopene soft capsules - Google Patents

Preparation technology of ganoderma lucidum spore oil and lycopene soft capsules Download PDF

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Publication number
CN106562422A
CN106562422A CN201610988194.XA CN201610988194A CN106562422A CN 106562422 A CN106562422 A CN 106562422A CN 201610988194 A CN201610988194 A CN 201610988194A CN 106562422 A CN106562422 A CN 106562422A
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China
Prior art keywords
ganoderma lucidum
lucidum spore
spore oil
lycopene
soft capsule
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CN201610988194.XA
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Chinese (zh)
Inventor
王勇
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Kang Tao Biological (nantong) Co Ltd
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Kang Tao Biological (nantong) Co Ltd
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Priority to CN201610988194.XA priority Critical patent/CN106562422A/en
Publication of CN106562422A publication Critical patent/CN106562422A/en
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a preparation technology of ganoderma lucidum spore oil and lycopene soft capsules. Each of the ganoderma lucidum spore oil and lycopene soft capsules consists of a content and a capsule material, wherein the content is made from the following component in proportion by weight: 50g of lycopene and 300g of ganoderma lucidum spore oil; the capsule material is made from the following components in proportion by weight: 50g of gelatin, 20g of glycerine, 50g of purified water, 0.5g of titanium dioxide, 0.14g of nacarat and 0.235g of cacao pigment. The production technology of the ganoderma lucidum spore oil and lycopene soft capsules disclosed by the invention is advanced and simple; the form of the soft capsules is adopted, so that the soft capsules are convenient to take, and rapid and complete to absorb, the effects of the ganoderma lucidum spore oil and lycopene soft capsules for regulating blood fat, enhancing immunity, improving sleep and contributing to postoperative chemoradiotherapy recovery are fully exerted, and the ganoderma lucidum spore oil and lycopene soft capsules are suitable for various crowds suffering from high blood fat and postoperative crowds; and the situation that ganoderma lucidum triterpene substances in the ganoderma lucidum spore oil are not oxidized can be effectively guaranteed, the efficacies of the ganoderma lucidum spore oil is guaranteed, the efficacies of the lycopene for preventing and restraining tumor, regulating cholesterol, eliminating free radicals and the like are increased, and the health-care effects of products, namely the ganoderma lucidum spore oil and lycopene soft capsules, are substantially strengthened.

Description

A kind of preparation technology of ganoderma lucidum spore oil soft capsule of lycopene
Technical field
The present invention relates to health products processing technique field, and in particular to a kind of ganoderma lucidum spore oil soft capsule of lycopene Preparation technology.
Background technology
It is ganoderma lucidum triterpene material to press down cancer active ingredient in ganoderma lucidum spore oil, but its property is unstable, it is easy to oxidation and Failure, therefore prevent ganoderma lucidum triterpene material to be oxidized the emphasis for being to ensure that ganoderma lucidum spore oil effect;And lycopene is western red Contained a kind of natural colouring matter in persimmon, is the most powerful antioxidant being found in the plant of nature at present.
The ganoderma lucidum spore oil soft capsule of lycopene of the present invention, ganoderma lucidum spore oil and lycopene 6 are pressed:1 this gold Ratio is used cooperatively, and is effectively guaranteed ganoderma lucidum triterpene material in ganoderma lucidum spore oil not oxidized, it is ensured that its effect, there is increase Lycopene prevention and the effects such as suppress tumour, adjust cholesterol, remove free radical so that product health-care effect significantly increases By force.
The content of the invention
It is an object of the invention to provide a kind of can effectively prevent ganoderma lucidum triterpene material in ganoderma lucidum spore oil not oxidized The preparation technology of ganoderma lucidum spore oil soft capsule of lycopene.
The technical solution used in the present invention is:
A kind of preparation technology of ganoderma lucidum spore oil soft capsule of lycopene, is made up of content and capsule material, and its innovative point is, institute Stating each component weight proportion in content is:Lycopene 50g, ganoderma lucidum spore oil 300g;Each component weight is matched somebody with somebody in the capsule material Than for:Gelatin 50g, glycerine 20g, purified water 50g, titanium dioxide 0.5g, famille rose 0.14g, cacao pigment 0.235g;Its is concrete Processing step is as follows:
1)Lycopene and ganoderma lucidum spore oil after the completion of proportioning is carried out after mixing 20min, to obtain content feed liquid;
2)60 DEG C will be heated to after glycerine after the completion of proportioning, purified water, titanium dioxide, famille rose, cacao pigment uniformly mixing After obtain mixed solution, then again the gelatin after proportioning added into mixed solution, be heated to 70 DEG C, the heat time is 2~3 little When, and vacuumize under -0.085MPa~-0.09MPa, while being stirred, the filtration of 100 mesh sieves is then carried out again, obtain Stand to after gelatin solution, be incubated, temperature is 60 DEG C;
3)The content feed liquid for obtaining and gelatin solution being carried out into pelleting process, temperature is 18~26 DEG C, relative humidity is 40%~ 50%, you can obtain soft capsule, and content is 350mg/ grains;
4)The soft capsule for obtaining is carried out into heat treatment, shaping time is 2~4 hours, and temperature is 18~26 DEG C, and relative humidity is 35%;
5)Soft capsule after heat treatment is dried, baking temperature is 25~30 DEG C, the time is 18~24 hours, relatively wet Spend for 35%;
6)Dried soft capsule is carried out to select ball, unqualified soft capsule is excluded, qualified soft capsule is carried out with 95% ethanol Cleaning, then be dried 1~2 hour, baking temperature is 25~30 DEG C, and relative humidity is 35%, obtains finished product soft capsule;
7)Finished product soft capsule is wrapped inside into dress, and 60/bottle.
Beneficial effects of the present invention are as follows:
Production technology of the present invention is advanced simple, and soft gelatin capsules make its taking convenience, absorb rapid complete, give full play to its regulation Blood fat, enhance immunity, the recovery for improving the health care of sleep, contributing to Post operation chemicotherapy, it is adaptable to all kinds of highs fat of blood and postoperative crowd; Can effectively ensure that ganoderma lucidum triterpene material is not oxidized in ganoderma lucidum spore oil, it is ensured that its effect, increased tomato red The effects such as element prevention and suppression tumour, regulation cholesterol, removing free radical so that product health-care effect is greatly enhanced.
Specific embodiment
Embodiment 1
A kind of preparation technology of ganoderma lucidum spore oil soft capsule of lycopene, is made up of, each component in content content and capsule material Weight proportion is:Lycopene 50g, ganoderma lucidum spore oil 300g;Each component weight proportion is in capsule material:Gelatin 50g, glycerine 20g, Purified water 50g, titanium dioxide 0.5g, famille rose 0.14g, cacao pigment 0.235g;Its concrete technology step is as follows:
1)Lycopene and ganoderma lucidum spore oil after the completion of proportioning is carried out after mixing 20min, to obtain content feed liquid;
2)60 DEG C will be heated to after glycerine after the completion of proportioning, purified water, titanium dioxide, famille rose, cacao pigment uniformly mixing After obtain mixed solution, then again the gelatin after proportioning added into mixed solution, be heated to 70 DEG C, the heat time is 2 hours, and And vacuumize under -0.085MPa, while being stirred, the filtration of 100 mesh sieves is then carried out again, obtain after gelatin solution stand, Insulation, temperature is 60 DEG C;
3)The content feed liquid for obtaining and gelatin solution are carried out into pelleting process, temperature is 18 DEG C, and relative humidity is 40%, you can To soft capsule, and content is 350mg/ grains;
4)The soft capsule for obtaining is carried out into heat treatment, shaping time is 2 hours, and temperature is 18 DEG C, and relative humidity is 35%;
5)Soft capsule after heat treatment is dried, baking temperature is 25 DEG C, and the time is 18 hours, and relative humidity is 35%;
6)Dried soft capsule is carried out to select ball, unqualified soft capsule is excluded, qualified soft capsule is carried out with 95% ethanol Cleaning, then be dried 1 hour, baking temperature is 25 DEG C, and relative humidity is 35%, obtains finished product soft capsule;
7)Finished product soft capsule is wrapped inside into dress, and 60/bottle.
Embodiment 2
A kind of preparation technology of ganoderma lucidum spore oil soft capsule of lycopene, is made up of, each component in content content and capsule material Weight proportion is:Lycopene 50g, ganoderma lucidum spore oil 300g;Each component weight proportion is in capsule material:Gelatin 50g, glycerine 20g, Purified water 50g, titanium dioxide 0.5g, famille rose 0.14g, cacao pigment 0.235g;Its concrete technology step is as follows:
1)Lycopene and ganoderma lucidum spore oil after the completion of proportioning is carried out after mixing 20min, to obtain content feed liquid;
2)60 DEG C will be heated to after glycerine after the completion of proportioning, purified water, titanium dioxide, famille rose, cacao pigment uniformly mixing After obtain mixed solution, then again the gelatin after proportioning added into mixed solution, be heated to 70 DEG C, the heat time is 3 hours, and And vacuumize under -0.09MPa, while being stirred, the filtration of 100 mesh sieves is then carried out again, obtain being stood after gelatin solution, protect Temperature, temperature is 60 DEG C;
3)The content feed liquid for obtaining and gelatin solution are carried out into pelleting process, temperature is 26 DEG C, and relative humidity is 50%, you can To soft capsule, and content is 350mg/ grains;
4)The soft capsule for obtaining is carried out into heat treatment, shaping time is 4 hours, and temperature is 26 DEG C, and relative humidity is 35%;
5)Soft capsule after heat treatment is dried, baking temperature is 30 DEG C, and the time is 24 hours, and relative humidity is 35%;
6)Dried soft capsule is carried out to select ball, unqualified soft capsule is excluded, qualified soft capsule is carried out with 95% ethanol Cleaning, then be dried 2 hours, baking temperature is 30 DEG C, and relative humidity is 35%, obtains finished product soft capsule;
7)Finished product soft capsule is wrapped inside into dress, and 60/bottle.
Embodiment 3
A kind of preparation technology of ganoderma lucidum spore oil soft capsule of lycopene, is made up of, each component in content content and capsule material Weight proportion is:Lycopene 50g, ganoderma lucidum spore oil 300g;Each component weight proportion is in capsule material:Gelatin 50g, glycerine 20g, Purified water 50g, titanium dioxide 0.5g, famille rose 0.14g, cacao pigment 0.235g;Its concrete technology step is as follows:
1)Lycopene and ganoderma lucidum spore oil after the completion of proportioning is carried out after mixing 20min, to obtain content feed liquid;
2)60 DEG C will be heated to after glycerine after the completion of proportioning, purified water, titanium dioxide, famille rose, cacao pigment uniformly mixing After obtain mixed solution, then again the gelatin after proportioning added into mixed solution, be heated to 70 DEG C, the heat time is 1.5 hours, And vacuumize under -0.087MPa, while being stirred, the filtration of 100 mesh sieves is then carried out again, obtain quiet after gelatin solution Put, be incubated, temperature is 60 DEG C;
3)The content feed liquid for obtaining and gelatin solution are carried out into pelleting process, temperature is 22 DEG C, and relative humidity is 45%, you can To soft capsule, and content is 350mg/ grains;
4)The soft capsule for obtaining is carried out into heat treatment, shaping time is 3 hours, and temperature is 22 DEG C, and relative humidity is 35%;
5)Soft capsule after heat treatment is dried, baking temperature is 27 DEG C, and the time is 21 hours, and relative humidity is 35%;
6)Dried soft capsule is carried out to select ball, unqualified soft capsule is excluded, qualified soft capsule is carried out with 95% ethanol Cleaning, then be dried 1.5 hours, baking temperature is 27 DEG C, and relative humidity is 35%, obtains finished product soft capsule;
7)Finished product soft capsule is wrapped inside into dress, and 60/bottle.
The above is the preferred embodiment of the present invention, it is impossible to the interest field of the present invention is limited with this.Should refer to Go out, for those skilled in the art, technical scheme is modified or equivalent, all Without departing from protection scope of the present invention.

Claims (1)

1. a kind of preparation technology of ganoderma lucidum spore oil soft capsule of lycopene, is made up of, it is characterised in that institute content and capsule material Stating each component weight proportion in content is:Lycopene 50g, ganoderma lucidum spore oil 300g;Each component weight is matched somebody with somebody in the capsule material Than for:Gelatin 50g, glycerine 20g, purified water 50g, titanium dioxide 0.5g, famille rose 0.14g, cacao pigment 0.235g;Its is concrete Processing step is as follows:
Lycopene and ganoderma lucidum spore oil after the completion of proportioning is carried out after mixing 20min, to obtain content feed liquid;
After being heated to 60 DEG C after the glycerine after the completion of proportioning, purified water, titanium dioxide, famille rose, cacao pigment uniformly mixing Mixed solution is obtained, then again the gelatin addition mixed solution after proportioning 70 DEG C is heated to into, the heat time is 2~3 hours, And vacuumize under -0.085MPa~-0.09MPa, while being stirred, the filtration of 100 mesh sieves is then carried out again, obtain bright Stand after glue, be incubated, temperature is 60 DEG C;
The content feed liquid for obtaining and gelatin solution are carried out into pelleting process, temperature is 18~26 DEG C, and relative humidity is 40%~50%, Soft capsule is obtained, and content is 350mg/ grains;
The soft capsule for obtaining is carried out into heat treatment, shaping time is 2~4 hours, and temperature is 18~26 DEG C, and relative humidity is 35%;
Soft capsule after heat treatment is dried, baking temperature is 25~30 DEG C, the time is 18~24 hours, relative humidity For 35%;
Dried soft capsule is carried out to select ball, unqualified soft capsule is excluded, qualified soft capsule is carried out clearly with 95% ethanol Wash, then be dried 1~2 hour, baking temperature is 25~30 DEG C, and relative humidity is 35%, obtains finished product soft capsule;
Finished product soft capsule is wrapped inside into dress, and 60/bottle.
CN201610988194.XA 2016-11-10 2016-11-10 Preparation technology of ganoderma lucidum spore oil and lycopene soft capsules Pending CN106562422A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110839881A (en) * 2019-11-26 2020-02-28 康道生物(南通)有限公司 Ganoderma lucidum spore oil lycopene soft capsule and preparation process thereof
WO2020113495A1 (en) * 2018-12-06 2020-06-11 江苏安惠生物科技有限公司 Soft ganoderma lucidum spore oil capsule
CN114053314A (en) * 2021-09-29 2022-02-18 康道生物(南通)有限公司 Experimental research method of anti-tumor ganoderma lucidum spore oil and lycopene compound preparation
WO2022105726A1 (en) * 2020-11-18 2022-05-27 中科健康产业集团股份有限公司 Production method for lycopene-containing granules with efficient antioxidation effect
CN114601162A (en) * 2022-03-22 2022-06-10 康道生物(南通)有限公司 Method and equipment for preparing ganoderma lucidum spore oil lycopene self-emulsifying soft capsules

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1586619A (en) * 2004-07-08 2005-03-02 乌鲁木齐优康来科技开发有限公司 Natural lycopene compound oil preparation and capsule and its preparing method and use
CN105876435A (en) * 2014-10-22 2016-08-24 会同县贤胜油业有限责任公司 Anti-oxidizing composition soft capsule and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1586619A (en) * 2004-07-08 2005-03-02 乌鲁木齐优康来科技开发有限公司 Natural lycopene compound oil preparation and capsule and its preparing method and use
CN105876435A (en) * 2014-10-22 2016-08-24 会同县贤胜油业有限责任公司 Anti-oxidizing composition soft capsule and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020113495A1 (en) * 2018-12-06 2020-06-11 江苏安惠生物科技有限公司 Soft ganoderma lucidum spore oil capsule
CN110839881A (en) * 2019-11-26 2020-02-28 康道生物(南通)有限公司 Ganoderma lucidum spore oil lycopene soft capsule and preparation process thereof
WO2022105726A1 (en) * 2020-11-18 2022-05-27 中科健康产业集团股份有限公司 Production method for lycopene-containing granules with efficient antioxidation effect
CN114053314A (en) * 2021-09-29 2022-02-18 康道生物(南通)有限公司 Experimental research method of anti-tumor ganoderma lucidum spore oil and lycopene compound preparation
CN114601162A (en) * 2022-03-22 2022-06-10 康道生物(南通)有限公司 Method and equipment for preparing ganoderma lucidum spore oil lycopene self-emulsifying soft capsules

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Application publication date: 20170419

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