CN105434718A - Medicine for treating turbid urine caused by damp-heat pouring downward syndrome - Google Patents

Medicine for treating turbid urine caused by damp-heat pouring downward syndrome Download PDF

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CN105434718A
CN105434718A CN201510983642.2A CN201510983642A CN105434718A CN 105434718 A CN105434718 A CN 105434718A CN 201510983642 A CN201510983642 A CN 201510983642A CN 105434718 A CN105434718 A CN 105434718A
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radix
herba
rhizoma
medicine
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张红
李振华
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Abstract

The invention discloses a medicine for treating turbid urine caused by a damp-heat pouring downward syndrome. The medicine is prepared from the following raw medicinal materials: coriaceous knotweed rhizome, galium aparine, shrubby breynia, maranta bicolor, leucas ciliate root, sophora davidii, olive kernels, senecio dianthus franch, agrimonia pilosa ldb, wight anotis, torenia fournieri, burmannia disticha, debregeasia longifolia, paulownia kawakamii, veronicastrum herb, phaseolus calcaratus, tartary buckwheat root and stem, elderberry, lemon root, scabrous doellingeria rhizome and root, herba eupatorii chinansis, rheum lidjiangense, climbing fig receptacle, dentiferous dendropanax root and stem, linum perenne, berchemia lineate and brooklet anemone root. The medicine disclosed by the invention has the beneficial effects that the medicine is used for treating the turbid urine caused by the damp-heat pouring downward syndrome, has the efficacies of clearing away heat and toxic materials, promoting urination, removing dampness, reducing swelling, relieving pain, and promoting blood circulation to remove blood stasis, and is good in effect, fast in curative effect, not easy to recur and free of toxic or side effect through scientific matrix conditioning.

Description

A kind of medicine for the treatment of damp heat downward flowing type turbid urine
Technical field
The present invention relates to tcm field, particularly a kind of medicine for the treatment of damp heat downward flowing type turbid urine.
Background technology
Turbid urine refers to turbid urine, in vain as the symptom of water from washing rice slurry.Cause the common disease of turbid urine to have filaricide, kidney consumptive disease, turbid, the kidney system carcinoma of essence, children's exogenous or internal injury, thorax abdomen wound or operation etc. also can cause turbid urine.When the clinical disease kind to taking turbid urine as primary symptom is not yet determined, can turbid urine to be checked as tentative diagnosis, and carry out determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.
Diagnosis: 1. urine microscopy has a large amount of pus cell person, is pyuria, does not belong to turbid urine, is more common in the disease such as kidney illness, kidney work, pyretic stranguria.If 2. when defecation, stem end flows out the thing of nebulousurine, and urine haze-free person, be called and " essence is turbid " do not belong to turbid urine.3. turbid urine is through the uroscopy person that turns out to be chyluria, and its pathological changes can be: (1) companion scrotum, lower limb enlargement, and skin is slightly thick in Corium elephatis, and blood smear discovers and seizes filaricide microfilariae of ohchocerciasis person, then turbid urine is caused by filaricide.(2) if emaciated physique, or there is pulmonary tuberculosis medical history person, should consider that turbid urine is kidney consumptive disease, caused by adipose membrane consumptive disease.(3) if find lump in breast, abdomen, then consider that turbid urine is caused by carcinoma.(4) if turbid urine appears in breast, trauma of abdomen or Post operation, turbid urine and wound should be considered, perform the operation relevant.4. children's in catching cold, diet is uncomfortable and in the situations such as dysfunction of the spleen in transportation, sometimes can occur turbid urine, uroscopy can find a large amount of phosphate, can die away without treatment.5. outside dehematize, urine, stool routine inspection, optionally do splanchnocoel x-ray, B ultrasound, CT and lymphography inspection, to help establishment and the discriminating of diagnosis.
Chinese medical discrimination is divided into, damp heat downward flowing type: turbid urine as wadding, or with grumeleuse, blood, has hotness, red tongue, greasy and thin fur or Huang, stringy pulse or number; Sinking of QI due to deficiency of the spleen type: turbid urine is as rice-washed water, or companion's hematuria, often because of fertile fat and the tired postemphasis of taking food, lusterless complexion, god is tired weak, pale tongue with thin fur, thready and soft pulse; To suffer from a deficiency of the kidney deficiency type: turbid urine is delayed, or bring out because of fatigue, urine is milky white as lipoid, or plate hematuria, lethargy, and lumbago lower limb is soft, dizziness and tinnitus, pale tongue or light red, deep-thready pulse or count accurately.
Because turbid urine rises because of many reasons, therefore entirety is treated, and cannot reach the basic for the treatment of.Therefore except symptomatic treatment, also to treat radical cure.The present invention is exactly that the turbid urine that causes with nephropathy is for treatment target.Chinese traditional treatment, has a lot of advantages.
Summary of the invention
In order to solve the problem, the invention provides a kind of medicine for the treatment of damp heat downward flowing type turbid urine.
In order to realize foregoing invention object, the invention provides a kind of medicine for the treatment of damp heat downward flowing type turbid urine, wherein, obtained by following raw medicinal material: Rhizoma Polygoni coriacei, Herba Galii Teneri, Folium et cacumen Breyniae Fruticosae, Rhizoma Marantae bicoloris, the Leucas ciliata Benth, Radix Sophorae Viciifoliae, Semen Canarii albi, Herba Senecionis Dianthui, Herba silenes fortunei, Anotis wightiana (Wall.) Hook.F., blue pig ear, water Flos Hostae Plantagineae, the Debregeasia orientalis C. J. Chen that comes into leaves, Catalpa ovata G. Don wood, Herba Veronicastri, Semen Phaseoli, Radix Et Rhizoma Fagopyri Tatarici, Ramulus Sambuci Williamsii, Radix Citri Limoniae, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix scopoliae sinensis, Rheum forrestii Diels, Fructus Fici Pumilae, Radix Dendropanacis, Iinum peerenne L., Radix berchemiae lineatae and Radix Anemones Rivularis.
Wherein, obtained by the raw medicinal material of following mass fraction: Rhizoma Polygoni coriacei 10-20 weight portion, Herba Galii Teneri 8-13 weight portion, Folium et cacumen Breyniae Fruticosae 2-4 weight portion, Rhizoma Marantae bicoloris 1-3 weight portion, Leucas ciliata Benth 10-15 weight portion, Radix Sophorae Viciifoliae 12-18 weight portion, Semen Canarii albi 7-14 weight portion, Herba Senecionis Dianthui 10-20 weight portion, Herba silenes fortunei 15-20 weight portion, Anotis wightiana (Wall.) Hook.F. 12-20 weight portion, blue pig ear 8-12 weight portion, water Flos Hostae Plantagineae 10-15 weight portion, come into leaves Debregeasia orientalis C. J. Chen 10-20 weight portion, Catalpa ovata G. Don wood 15-23 weight portion, Herba Veronicastri 10-20 weight portion, Semen Phaseoli 10-20 weight portion, Radix Et Rhizoma Fagopyri Tatarici 8-15 weight portion, Ramulus Sambuci Williamsii 10-15 weight portion, Radix Citri Limoniae 10-20 weight portion, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 4-9 weight portion, Radix scopoliae sinensis 10-13 weight portion, Rheum forrestii Diels 6-12 weight portion, Fructus Fici Pumilae 5-10 weight portion, Radix Dendropanacis 15-18 weight portion, Iinum peerenne L. 10-14 weight portion, Radix berchemiae lineatae 6-12 weight portion and Radix Anemones Rivularis 2-4 weight portion.
Wherein, obtained by the raw medicinal material of following mass fraction: Rhizoma Polygoni coriacei 15 weight portion, Herba Galii Teneri 10 weight portion, Folium et cacumen Breyniae Fruticosae 3 weight portion, Rhizoma Marantae bicoloris 2 weight portion, the Leucas ciliata Benth 12 weight portion, Radix Sophorae Viciifoliae 15 weight portion, Semen Canarii albi 12 weight portion, Herba Senecionis Dianthui 15 weight portion, Herba silenes fortunei 16 weight portion, Anotis wightiana (Wall.) Hook.F. 15 weight portion, blue pig ear 10 weight portion, water Flos Hostae Plantagineae 12 weight portion, the Debregeasia orientalis C. J. Chen that comes into leaves 15 weight portion, Catalpa ovata G. Don wood 18 weight portions, Herba Veronicastri 15 weight portion, Semen Phaseoli 15 weight portion, Radix Et Rhizoma Fagopyri Tatarici 12 weight portion, Ramulus Sambuci Williamsii 12 weight portion, Radix Citri Limoniae 15 weight portion, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 6 weight portion, Radix scopoliae sinensis 12 weight portion, Rheum forrestii Diels 8 weight portion, Fructus Fici Pumilae 8 weight portion, Radix Dendropanacis 16 weight portion, Iinum peerenne L. 12 weight portion, Radix berchemiae lineatae 8 weight portion and Radix Anemones Rivularis 3 weight portion.
In order to achieve the above object, present invention also offers the preparation method of the medicine of described treatment damp heat downward flowing type turbid urine, comprise the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 3 ~ 7 times, mixture is the ethanol of 80% ~ 90%, be heated to boiling reflux 2 ~ 4 hours, filter, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being evaporated to 50 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.09Mpa, relative density is the mastic of 1.04 ~ 1.14, spraying dry, the inlet temperature 165 ~ 175 DEG C of spray dryer, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.2 ~ 0.4 times and 0.1 ~ 0.2 times in the dried cream powder obtained, makes granule, in 45 ~ 50 DEG C of dryings, obtains granule.
Medicine of the present invention, treatment damp heat downward flowing type turbid urine, has heat-clearing and toxic substances removing, changes that water conservancy wets, effect of relieving distension pain relieving and blood circulation promoting and blood stasis dispelling, and by nurse one's health the science of matrix, effective, curative effect soon, not easily recurs, and has no side effect.
Detailed description of the invention
The invention provides a kind of medicine for the treatment of damp heat downward flowing type turbid urine, wherein, following raw medicinal material is comprised: Rhizoma Polygoni coriacei, Herba Galii Teneri, Folium et cacumen Breyniae Fruticosae, Rhizoma Marantae bicoloris, the Leucas ciliata Benth, Radix Sophorae Viciifoliae, Semen Canarii albi, Herba Senecionis Dianthui, Herba silenes fortunei, Anotis wightiana (Wall.) Hook.F., blue pig ear, water Flos Hostae Plantagineae, the Debregeasia orientalis C. J. Chen that comes into leaves, Catalpa ovata G. Don wood, Herba Veronicastri, Semen Phaseoli, Radix Et Rhizoma Fagopyri Tatarici, Ramulus Sambuci Williamsii, Radix Citri Limoniae, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix scopoliae sinensis, Rheum forrestii Diels, Fructus Fici Pumilae, Radix Dendropanacis, Iinum peerenne L., Radix berchemiae lineatae and Radix Anemones Rivularis.Ingredients scientific matching, reaches the object for the treatment of damp heat downward flowing type turbid urine, has good effect.
The pharmacology of various raw medicinal material is as follows:
Rhizoma Polygoni coriacei: [source] is the rhizome of polygonaceae plant leather leaf knotweed.Autumn excavates, and cleans, and selenium is done.[nature and flavor] " the practical Chinese herbal medicine in Guangxi newly selects ": " puckery micro-hardship, flat, nontoxic." [function cures mainly] heat clearing away, removing toxic substances, convergence, granulation promoting.Control dysentery, diarrhoea, carbuncle, hemorrhoid, burn.1. " the practical Chinese herbal medicine in Guangxi newly selects ": " removing toxic substances, convergence, granulation promoting.Control venom, burn, dysentery, diarrhoea." 2. " register planted by Guangxi medicine ": " heat clearing away. convergence, go to amass, puerperal enriches blood.Control the intestines and stomach damp and hot, bloody dysentery, erosion of the oral mucosa, carbuncle, hemorrhoid, burn."
Herba Galii Teneri: [source] draws the herb of rattan or thick Ye Lala rattan for Maguireothamnus speciosus.Autumn gathers, and dries or dries.[nature and flavor] acrid in the mouth; Micro-hardship; Cold nature.[return through] is few cloudy; Taiyin channels.[function cures mainly] heat-clearing and toxic substances removing; Inducing diuresis for treating stranguria syndrome; Reducing swelling and alleviating pain.Main swollen ulcer drug; Mastitis; Appendicitis; Edema; Cold, fever; Dysentery; Urinary tract infection; Hematuria; Gingival hemorrhage; Knife injury is hemorrhage.
Folium et cacumen Breyniae Fruticosae: [source] Euphorbiaceae mountain paint stem platymiscium black flour tree, is used as medicine with root, leaf.The whole year can adopt, and clean section is dried.[nature and flavor] micro-hardship, cool.[function cures mainly] heat-clearing and toxic substances removing, dissipating blood stasis, pain relieving, antipruritic.
Rhizoma Marantae bicoloris: [source] Marantaceae Rhizoma Marantae bicoloris, is used as medicine with root stock.[habitats distribution] Guangdong.[nature and flavor] micro-bitter, acrid, cold.[function cures mainly] clearing heat for detumescence.
The Leucas ciliata Benth: [source] is the root of labiate Herba leucadis ciliatae.[original shape state] phytomorph is " Herba leucadis ciliatae " bar in detail.[function cures mainly] dispels the wind removing toxic substances, liver-smoothing, qi-regulating.Control depression of liver-QI, rheumatic numbness and pain, dysentery, infantile malnutrition, erythra, proctoptosis.
Radix Sophorae Viciifoliae: [source] is the root of leguminous plant Radix Sophorae Viciifoliae.Summer gathers.[nature and flavor] are " Guizhou medical herbs " 1.: " property is put down, bitter in the mouth." 2. " mountain of papers Chinese herbal medicine ": " bitter in the mouth, cold in nature." [function cures mainly] be " Guizhou medical herbs " 1.: " heat clearing away, removing heat from blood, removing toxic substances.Control nose bleeding, have blood in stool." 2. " mountain of papers Chinese herbal medicine ": " heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Control dysentery, cystitis, hematuria, edema."
Semen Canarii albi: [source] is the kernel of olive subject plant Fructus Canarii albi.Collect pit, smash nucleocapsid, take out kernel, dry.[nature and flavor] are " detailed outline " 1.: " sweet, flat, nontoxic." 2. " medical center bun is wanted ": " is sweet light." [function cures mainly] moisturizes, and separates fish, alcoholism.1. " Kaibao Bencao ": " grind the dry pain of deposited lips." 2. " medical center bun is wanted ": " lung moistening, relieves the effect of alcohol, separates worm for fishing poison." 3. " occupying diet spectrum with breath ": " lung moistening, removing toxic substances, parasite killing, rare pox, fish raw meat processed."
Herba Senecionis Dianthui: [source] Compositae Senecio plant Senecio dianthus, with all herbal medicine.Autumn gathers herb, and cutting is dried.[nature and flavor] are bitter, cold.[function cures mainly] heat-clearing and toxic substances removing, wind-damp dispelling, antipruritic.For acute conjunctivitis, furuncle, dermatitis, traumatic injury.
Herba silenes fortunei: [nature and flavor] " Zhejiang conventional medical herbs among the people ": " pungent puckery, cool." [function cures mainly] heat clearing away profit alunite, tonify deficiency is invigorated blood circulation.Control urinary tract infection, leucorrhea, dysentery, body is empty after being ill, turns round, dampens.1. " Jiangsu medical material will ": " strengthening by means of tonics.Control body tiger or weak few power after being ill." 2. " Zhejiang conventional medical herbs among the people ": " clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling."
Anotis wightiana (Wall.) Hook.F.: the false Auricled Hedyotis Herb of the false plants of Hedyotis caudal lobe of [source] Rubiaceae, with all herbal medicine.Xia Qiu gathers, and dries.[nature and flavor] are sweet, sour, flat.[function cures mainly] stomach invigorating, dampness removing, disappear infantile malnutrition.For infantile malnutrition, edema due to deficiency of the spleen, jaundice.
Blue pig ear: [source] Scrophulariaceae blue pig ear, with all herbal medicine.[habitats distribution] Zhejiang, Taiwan, Guangdong, Guangxi, Guizhou.[pharmacological action] bacteriostatic experiment: the antibacterial potency of herb decocting liquid to the O17 strain of icterogenic spirochetosis bleeding type and bad strain is 1/400.[nature and flavor] are bitter, cool.[function cures mainly] heat-clearing and toxic substances removing, dampness removing, cough-relieving, stomach function regulating preventing or arresting vomiting, blood stasis dispelling.
Water Flos Hostae Plantagineae: medical material Ji Yuan: be herb or the root of Burmanniaceae vegetation water Flos Hostae Plantagineae.[nature and flavor] are light; Cold.[function cures mainly] clearing away heat-damp and promoting diuresis; Cough-relieving.Main yellowish or reddish urine; Cough
Come into leaves Debregeasia orientalis C. J. Chen: [source] medical material Ji Yuan: for contrayerva comes into leaves the stem and leaf of Debregeasia orientalis C. J. Chen.[nature and flavor] are pungent; Bitter; Cool in nature.[function cures mainly] dispelling wind stopping cough; Clearing away heat-damp and promoting diuresis.Main Common Cold; Cough; Pyretic arthralgia; Cystitis; Innominate toxic swelling; Toothache.
Catalpa ovata G. Don wood: [source] Moraceae Catalpa ovata G. Don wood, is used as medicine with root bark, leaf.[habitats distribution] Taiwan, Guangdong, Guangxi, Yunnan.[function cures mainly] QI invigorating, lung moistening, invigorates blood circulation, eliminating dampness by diuresis diuresis.Control infirmities and diseases, traumatic injury, dysuria, damp-heat diarrhea.
Herba Veronicastri: [source] Scrophulariaceae Herba veronicastri villosuli platymiscium stenostachyous veronicastrum herb, Herba veronicastri villosuli or veronicastrum latifoliumYamazaki are all with all herbal medicine.The four seasons can adopt, and clean and dry or using fresh herb.[nature and flavor] micro-hardship, cool.[function cures mainly] heat-clearing and toxic substances removing, inducing diuresis to remove edema, eliminating stasis to stop pain.For cough due to lung-heat, hepatitis, edema; Traumatic injury is controlled in external, venom, burn and scald.
Semen Phaseoli: [source] this product is the dry mature seed of leguminous plant Semen Phaseoli or Semen Phaseoli.Autumn fruit maturation and do not ftracture time to choose Herb, dry, lay seed, removing impurity, then dry.[nature and flavor] are sweet, sour, flat.[return through] GUIXIN, small intestine meridian.[function cures mainly] inducing diuresis to remove edema, removing toxic substances and promoting pus discharge.For edema distension, beriberi limb swells, jaundice dark coloured urine, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.
Radix Et Rhizoma Fagopyri Tatarici: [nature and flavor] are sweet; Property is put down.[return through] spleen; Stomach; Large intestine channel.[function cures mainly] spleen invigorating row is stagnant; Regulating QI to relieve pain; Removing toxic substances and promoting subsidence of swelling.Main epigastric distending pain; Dyspepsia; Dysentery; Lumbago and skelalgia; Traumatic injury; Carbuncle malignant boil; Lyssodexis.
Ramulus Sambuci Williamsii: [nature and flavor] are sweet, bitter, flat.[return through] returns Liver Channel.[function cures mainly] reunion of bone, promoting blood circulation and stopping pain, expelling wind and removing dampness.For fracture, traumatic injury, rheumatic arthritis, gout, Kaschin-Beck disease, acute and chronic nephritis; Wound hemorrhage is controlled in external.
Radix Citri Limoniae: the root that [source] is rutaceae Canton lemon or lemon.[nature and flavor] are pungent; Bitter; Tepor.[return through] liver; Kidney channel.[function cures mainly] circulation of qi promoting is stopped blooding; Pain relieving; Cough-relieving.Main stomachache; Colicky; Traumatic injury; Cough.
Rhizoma et Radix Doellingeriae (Herba Doellingeriae): [source] is Compositae Doellingeria plant Rhizoma et Radix Doellingeriae (Herba Doellingeriae), is used as medicine with herb and root.Summer taps herb, and autumn adopts root, cleans and dries.[nature and flavor] are pungent, sweet, cold.[function cures mainly] heat-clearing and toxic substances removing, wind-expelling pain-stopping.For venom, rheumatic arthritis, traumatic injury, headache due to common cold, conjunctival congestion and swelling pain, laryngopharynx swelling and pain; Furuncle is controlled in external, venom.
Radix scopoliae sinensis: [source] is the root of the new hyoscyami of plant of Solanaceae.Autumn and winter gather, and clean; Section is dried.[nature and flavor] work hard, temperature, severe toxicity.[function cures mainly] delivers cold expelling, relaxing muscles and tendons and activating QI and blood in the collateral, pain relieving.
Rheum forrestii Diels: [source] Polygonaceae Rheum forrestii Diels, is used as medicine with root.[habitats distribution] Yunnan.[nature and flavor] are bitter, puckery, cold.[function cures mainly] promoting blood circulation and hemostasis, anti-inflammatory analgetic.Cure mainly traumatic hemorrhage, traumatic injury, dysentery.
Fructus Fici Pumilae: [nature and flavor] are sweet.Flat. 1. " detailed outline ": " sweet, flat, puckery, nontoxic." 2. " must book on Chinese herbal medicine be joined ": " sweet acid, cold." [return through] " must book on Chinese herbal medicine be joined ": " sun of starting with, Foot yangming Channel blood system." [function cures mainly] lactogenesis, dampness removing, invigorates blood circulation, detumescence.Control agalactia, seminal emission, stranguria with turbid discharge, chyluria, chronic dysentery, hemorrhoidal bleeding, discharging fresh blood stool, carbuncle, furuncle.
Radix Dendropanacis: [source] is Araliaceae tree ginseng platymiscium tree ginseng, is used as medicine with root or branch and leaf.[nature and flavor] are sweet, temperature.[function cures mainly] expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation.For migraine, brachial plexus neuritis, rheumatic arthritis, rheumatoid arthritis, lumbar muscle strain, chronic lambago and skelalgia, hemiplegia, traumatic injury, bruise; External is controlled on cutter hemorrhage.
Iinum peerenne L.: [source] flax family (Linaceae) Iinum peerenne L., is used as medicine with flower, fruit.[habitats distribution] Shaanxi, the Inner Mongol, Gansu, Qinghai.[function cures mainly] restores menstrual flow and invigorates blood circulation.Tibetan medicine is used for controlling uterus blood stasis, amenorrhea, physical weakness.
Radix berchemiae lineatae: [source] Rhamnaceae hook fold plant spire Radix Berchemiae Giraldianae, is used as medicine with root.The whole year can adopt, and cleans section, dries.[nature and flavor] micro-hardship, puckery, flat.[function cures mainly] removing stasis to stop bleeding, antitussive pain relieving.For hemoptysis of pulmonary tuberculosis, taste-blindness rate is hemorrhage, schizophrenia, traumatic injury, rheumatic ostalgia, furuncle furuncle and phyma, deradenoncus, painful and swollen testis.
Radix Anemones Rivularis: [source] Ranunculaceae thimbleweed Herba Veronicastri Sibirici, is used as medicine with root.Autumn adopts root, cleans and dries.[nature and flavor] are pungent, bitter, cold.[function cures mainly] clearing away heat-damp and promoting diuresis, reducing swelling and alleviating pain.For laryngopharynx swelling and pain, tonsillitis, toothache, stomachache, acute hepatitis, chronic hepatitis, rheumatalgia, traumatic injury.
The present invention preferably only has above raw medicinal material to obtain.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1
Proportioning: Rhizoma Polygoni coriacei 10g, Herba Galii Teneri 8g, Folium et cacumen Breyniae Fruticosae 2g, Rhizoma Marantae bicoloris 1g, Leucas ciliata Benth 10g, Radix Sophorae Viciifoliae 12g, Semen Canarii albi 7g, Herba Senecionis Dianthui 10g, Herba silenes fortunei 15g, Anotis wightiana (Wall.) Hook.F. 12g, blue pig ear 8g, water Flos Hostae Plantagineae 10g, come into leaves Debregeasia orientalis C. J. Chen 10g, Catalpa ovata G. Don wood 15g, Herba Veronicastri 10g, Semen Phaseoli 10g, Radix Et Rhizoma Fagopyri Tatarici 8g, Ramulus Sambuci Williamsii 10g, Radix Citri Limoniae 10g, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 4g, Radix scopoliae sinensis 10g, Rheum forrestii Diels 6g, Fructus Fici Pumilae 5g, Radix Dendropanacis 15g, Iinum peerenne L. 10g, Radix berchemiae lineatae 6g and Radix Anemones Rivularis 2g.
Its preparation method is:
Step 1: by Semen Canarii albi, Semen Phaseoli and Radix Citri Limoniae grind into powder; Step 2: get 80% soak with ethanol 1 hour, heating extraction 2 times that surplus stock medical material adds 4 times amount again, add 1.0 hours 80% ethanol used times of 3 times amount at every turn, filter to obtain extracting solution and medicinal residues, the extracting solution of twice is merged, be the ultrafiltration post ultrafiltration of 54000 again through the molecular weight that dams, ultrafiltration decompression removing ethanol, during simmer down to 90 DEG C, relative density is the extractum of 1.03, becomes component 1; Step 3: the medicinal residues that step 2 obtains add 2 times amount water soaking 1.0 hours, extracts 1 time, is the extractum of 1.1, as component 2 by relative density during extracting solution heating under reduced pressure simmer down to 85 DEG C for 1.0 hours; Step 4: component 1, component 2 are mixed with the powder that step 1 obtains, adds and is twisted into honey refining pill relative to the Mel of mixture 2 times amount.
Embodiment 2
Proportioning: Rhizoma Polygoni coriacei 20g, Herba Galii Teneri 13g, Folium et cacumen Breyniae Fruticosae 4g, Rhizoma Marantae bicoloris 3g, Leucas ciliata Benth 15g, Radix Sophorae Viciifoliae 18g, Semen Canarii albi 14g, Herba Senecionis Dianthui 20g, Herba silenes fortunei 20g, Anotis wightiana (Wall.) Hook.F. 20g, blue pig ear 12g, water Flos Hostae Plantagineae 15g, come into leaves Debregeasia orientalis C. J. Chen 20g, Catalpa ovata G. Don wood 23g, Herba Veronicastri 20g, Semen Phaseoli 20g, Radix Et Rhizoma Fagopyri Tatarici 15g, Ramulus Sambuci Williamsii 15g, Radix Citri Limoniae 20g, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 9g, Radix scopoliae sinensis 13g, Rheum forrestii Diels 12g, Fructus Fici Pumilae 10g, Radix Dendropanacis 18g, Iinum peerenne L. 14g, Radix berchemiae lineatae 12g and Radix Anemones Rivularis 4g.
Its preparation method is:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 5 times, mixture is the ethanol of 85%, be heated to boiling reflux 3 hours, filter, adopt percolation with the speed of 2ml per minute slowly percolation, collect percolate, when being evaporated to 55 DEG C subsequently under vacuum 0.08Mpa, relative density is the mastic of 1.1, spraying dry, the inlet temperature 170 DEG C of spray dryer, leaving air temp 80 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.3 times and 0.2 times in the dried cream powder obtained, makes granule, in 50 DEG C of dryings, obtains granule.
Embodiment 3
Proportioning: Rhizoma Polygoni coriacei 15g, Herba Galii Teneri 10g, Folium et cacumen Breyniae Fruticosae 3g, Rhizoma Marantae bicoloris 2g, Leucas ciliata Benth 12g, Radix Sophorae Viciifoliae 15g, Semen Canarii albi 12g, Herba Senecionis Dianthui 15g, Herba silenes fortunei 16g, Anotis wightiana (Wall.) Hook.F. 15g, blue pig ear 10g, water Flos Hostae Plantagineae 12g, come into leaves Debregeasia orientalis C. J. Chen 15g, Catalpa ovata G. Don wood 18g, Herba Veronicastri 15g, Semen Phaseoli 15g, Radix Et Rhizoma Fagopyri Tatarici 12g, Ramulus Sambuci Williamsii 12g, Radix Citri Limoniae 15g, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 6g, Radix scopoliae sinensis 12g, Rheum forrestii Diels 8g, Fructus Fici Pumilae 8g, Radix Dendropanacis 16g, Iinum peerenne L. 12g, Radix berchemiae lineatae 8g and Radix Anemones Rivularis 3g.
Its preparation method is:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 5 times, mixture is the ethanol of 85%, be heated to boiling reflux 3 hours, filter, adopt percolation with the speed of 2ml per minute slowly percolation, collect percolate, when being evaporated to 60 DEG C subsequently under vacuum 0.08Mpa, relative density is the mastic of 1.1, spraying dry, the inlet temperature 175 DEG C of spray dryer, leaving air temp 85 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.3 times and 0.2 times in the dried cream powder obtained, makes granule, in 50 DEG C of dryings, obtains granule.
The toxicity test of medicine
1. acute toxicity test: with the medicine of the embodiment of the present invention 1 for object, gives white mouse large enteral dispensing, observes 7 for 100 times of clinical consumption per day.The all animals of result are strong deposits, and its activity, diet, hair, Excreta are no abnormal, have no toxic reaction.Irritation test is carried out to white mouse vagina and damaged skin, there are no irritative response and other untoward reaction.Toxicity test proves, the present invention does not have toxic action and untoward reaction, and clinical practice is safe and reliable.
2. long term toxicity test: the medicine of the embodiment of the present invention 3 presses 13,30 and 40g crude drug/kg continuous use 16 weeks (1.0ml/100g body weight to mice, every day 2 times) and drug withdrawal after 4 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of medicine of the present invention to mice all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 16 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Clinical trial
Case selection: during selecting in May ,-2014 in May, 2013, patient's totally 150 examples of the damp heat downward flowing type turbid urine of certain central hospital's diagnosis and treatment.Wherein, man 72 example, female 78 example.Be divided into three groups at random, often organize 50 people, embodiment 1 group, embodiment 2 groups and embodiment 3 groups.Three groups of patients comparing difference not statistically significant in age, sex, state of an illness weight, has comparability, and according to the weight out-patient treatment of the state of an illness.
Diagnostic criteria:
1, with turbid urine, milky white as cream be primary symptom, or companion see hematuria, clot;
2, often because of oils and fats, protein diet, overfatigue and bringing out, or increase the weight of;
3, damp heat downward flowing type: turbid urine as wadding, or with grumeleuse, blood, has hotness, red tongue, greasy and thin fur or Huang, stringy pulse or number.
Therapeutic Method:
Embodiment 1 group: this group uses the honey of embodiments of the invention 1 refining pill to treat.Each 1 ball, 3 times on the one 5 days is a course for the treatment of, treats 3 courses for the treatment of.
Embodiment 2 groups: this group uses the granule of embodiments of the invention 2 to treat.Each oral 5g, 3 times on the one 5 days is a course for the treatment of, treats 3 courses for the treatment of.
Embodiment 3 groups: this group uses the granule of embodiments of the invention 3 to treat.Each oral 5g, 3 times on the one 5 days is a course for the treatment of, treats 3 courses for the treatment of.
Efficacy evaluation
1, fully recover in the recent period: clinical symptom disappearance, routine urinalysis is normal, continuous three feminine genders of ether experiment.
2, take a turn for the better: chyluria basic controlling, lab testing all take a favorable turn.
3, invalid: symptom and lab testing all do not improve.
Therapeutic outcome
Table 1 is the treatment situation contrast of each group
Group Recent healing Take a turn for the better Invalid
Embodiment 1 group 50(100%) 0(0%) 0(0%)
Embodiment 2 groups 50(100%) 0(0%) 0(0%)
Embodiment 3 groups 50(100%) 0(0%) 0(0%)
As can be seen from Table 1, the therapeutic effect of three embodiment groups is all fine, it can thus be appreciated that medicine of the present invention, in treatment damp heat downward flowing type turbid urine, therapeutic effect is good, determined curative effect.
Table 2 is the treatment time contrast of the recent healing of each group
Group Healing number First course for the treatment of Second course for the treatment of 3rd course for the treatment of
Embodiment 1 group 50 15(30%) 18(36%) 17(34%)
Embodiment 2 groups 50 16(32%) 20(40%) 14(28%)
Embodiment 3 groups 50 17(34%) 20(40%) 23(46%)
As can be seen from Table 2, medicine of the present invention, in treatment damp heat downward flowing type turbid urine, treatment speed is fast, instant effect.
Table 3 is recurrence and side effect contrast (toxic and side effects rate=side effect number/total number of persons, relapse rate=recurrence number/clinical cure number) of each group
Group Toxic and side effects incidence rate Relapse rate
Embodiment 1 group 0(0%) 0(0%)
Embodiment 2 groups 0(0%) 0(0%)
Embodiment 3 groups 0(0%) 0(0%)
As can be seen from Table 3, Drug therapy damp heat downward flowing type turbid urine of the present invention, does not have toxic and side effects, does not recur.
Model case: Shandong Prov. Hospital accepts a patient of diagnosis and treatment, man, 35 years old, suffers from nephritis, causes damp heat downward flowing type turbid urine half a year.The granule of embodiments of the invention 3 is used to treat.Each oral 5g, 3 times on the one 5 days is a course for the treatment of, cures in the recent period after treating 2 courses for the treatment of.In therapeutic process, do not occur other untoward reaction, the later stage follows up half a year, does not recur.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (3)

1. treat the medicine of damp heat downward flowing type turbid urine for one kind, it is characterized in that, obtained by following raw medicinal material: Rhizoma Polygoni coriacei, Herba Galii Teneri, Folium et cacumen Breyniae Fruticosae, Rhizoma Marantae bicoloris, the Leucas ciliata Benth, Radix Sophorae Viciifoliae, Semen Canarii albi, Herba Senecionis Dianthui, Herba silenes fortunei, Anotis wightiana (Wall.) Hook.F., blue pig ear, water Flos Hostae Plantagineae, the Debregeasia orientalis C. J. Chen that comes into leaves, Catalpa ovata G. Don wood, Herba Veronicastri, Semen Phaseoli, Radix Et Rhizoma Fagopyri Tatarici, Ramulus Sambuci Williamsii, Radix Citri Limoniae, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix scopoliae sinensis, Rheum forrestii Diels, Fructus Fici Pumilae, Radix Dendropanacis, Iinum peerenne L., Radix berchemiae lineatae and Radix Anemones Rivularis.
2. the medicine for the treatment of damp heat downward flowing type turbid urine according to claim 1, it is characterized in that, obtained by the raw medicinal material of following mass fraction: Rhizoma Polygoni coriacei 10-20 weight portion, Herba Galii Teneri 8-13 weight portion, Folium et cacumen Breyniae Fruticosae 2-4 weight portion, Rhizoma Marantae bicoloris 1-3 weight portion, Leucas ciliata Benth 10-15 weight portion, Radix Sophorae Viciifoliae 12-18 weight portion, Semen Canarii albi 7-14 weight portion, Herba Senecionis Dianthui 10-20 weight portion, Herba silenes fortunei 15-20 weight portion, Anotis wightiana (Wall.) Hook.F. 12-20 weight portion, blue pig ear 8-12 weight portion, water Flos Hostae Plantagineae 10-15 weight portion, come into leaves Debregeasia orientalis C. J. Chen 10-20 weight portion, Catalpa ovata G. Don wood 15-23 weight portion, Herba Veronicastri 10-20 weight portion, Semen Phaseoli 10-20 weight portion, Radix Et Rhizoma Fagopyri Tatarici 8-15 weight portion, Ramulus Sambuci Williamsii 10-15 weight portion, Radix Citri Limoniae 10-20 weight portion, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 4-9 weight portion, Radix scopoliae sinensis 10-13 weight portion, Rheum forrestii Diels 6-12 weight portion, Fructus Fici Pumilae 5-10 weight portion, Radix Dendropanacis 15-18 weight portion, Iinum peerenne L. 10-14 weight portion, Radix berchemiae lineatae 6-12 weight portion and Radix Anemones Rivularis 2-4 weight portion.
3. the medicine for the treatment of damp heat downward flowing type turbid urine according to claim 1 and 2, it is characterized in that, obtained by the raw medicinal material of following mass fraction: Rhizoma Polygoni coriacei 15 weight portion, Herba Galii Teneri 10 weight portion, Folium et cacumen Breyniae Fruticosae 3 weight portion, Rhizoma Marantae bicoloris 2 weight portion, the Leucas ciliata Benth 12 weight portion, Radix Sophorae Viciifoliae 15 weight portion, Semen Canarii albi 12 weight portion, Herba Senecionis Dianthui 15 weight portion, Herba silenes fortunei 16 weight portion, Anotis wightiana (Wall.) Hook.F. 15 weight portion, blue pig ear 10 weight portion, water Flos Hostae Plantagineae 12 weight portion, the Debregeasia orientalis C. J. Chen that comes into leaves 15 weight portion, Catalpa ovata G. Don wood 18 weight portions, Herba Veronicastri 15 weight portion, Semen Phaseoli 15 weight portion, Radix Et Rhizoma Fagopyri Tatarici 12 weight portion, Ramulus Sambuci Williamsii 12 weight portion, Radix Citri Limoniae 15 weight portion, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 6 weight portion, Radix scopoliae sinensis 12 weight portion, Rheum forrestii Diels 8 weight portion, Fructus Fici Pumilae 8 weight portion, Radix Dendropanacis 16 weight portion, Iinum peerenne L. 12 weight portion, Radix berchemiae lineatae 8 weight portion and Radix Anemones Rivularis 3 weight portion.
CN201510983642.2A 2015-12-24 2015-12-24 Medicine for treating turbid urine caused by damp-heat pouring downward syndrome Withdrawn CN105434718A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1872247A (en) * 2006-04-20 2006-12-06 林莲球 Medication of medicinal broth for treating disease of turbid urine in type of accumulation of damp-heat in the body, and preparation method
CN101843872A (en) * 2010-05-25 2010-09-29 泰一和浦(北京)中医药研究院有限公司 Chinese medicinal composition for treating turbid urine and preparation method thereof
CN103751656A (en) * 2014-01-23 2014-04-30 王芳 Traditional Chinese medicine decoction for treating turbid urea disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1872247A (en) * 2006-04-20 2006-12-06 林莲球 Medication of medicinal broth for treating disease of turbid urine in type of accumulation of damp-heat in the body, and preparation method
CN101843872A (en) * 2010-05-25 2010-09-29 泰一和浦(北京)中医药研究院有限公司 Chinese medicinal composition for treating turbid urine and preparation method thereof
CN103751656A (en) * 2014-01-23 2014-04-30 王芳 Traditional Chinese medicine decoction for treating turbid urea disease

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Application publication date: 20160330