CN105431172A - 炎症性病症的治疗 - Google Patents

炎症性病症的治疗 Download PDF

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Publication number
CN105431172A
CN105431172A CN201480030407.7A CN201480030407A CN105431172A CN 105431172 A CN105431172 A CN 105431172A CN 201480030407 A CN201480030407 A CN 201480030407A CN 105431172 A CN105431172 A CN 105431172A
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CN
China
Prior art keywords
compound
hydrocarbyl
disease
use according
nalidixic acid
Prior art date
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Pending
Application number
CN201480030407.7A
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English (en)
Chinese (zh)
Inventor
艾伦·莱斯利·罗瑟尔
杰里米·吉尔伯特·温特尔
罗伯特·亚瑟·斯科芬
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Cresset Biomolecular Discovery Ltd
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Cresset Biomolecular Discovery Ltd
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Filing date
Publication date
Priority claimed from GB201306411A external-priority patent/GB201306411D0/en
Priority claimed from GB201306413A external-priority patent/GB201306413D0/en
Application filed by Cresset Biomolecular Discovery Ltd filed Critical Cresset Biomolecular Discovery Ltd
Publication of CN105431172A publication Critical patent/CN105431172A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
CN201480030407.7A 2013-04-09 2014-04-09 炎症性病症的治疗 Pending CN105431172A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB201306411A GB201306411D0 (en) 2013-04-09 2013-04-09 Treatment of inflammatory conditions
GB1306411.8 2013-04-09
GB201306413A GB201306413D0 (en) 2013-04-09 2013-04-09 The local treatment of ophthalmic diseases
GB1306413.4 2013-04-09
PCT/GB2014/051109 WO2014167327A1 (en) 2013-04-09 2014-04-09 The treatment of inflammatory disorders

Publications (1)

Publication Number Publication Date
CN105431172A true CN105431172A (zh) 2016-03-23

Family

ID=50489339

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480030407.7A Pending CN105431172A (zh) 2013-04-09 2014-04-09 炎症性病症的治疗
CN201480030418.5A Pending CN105555364A (zh) 2013-04-09 2014-04-09 炎症性眼科疾病的局部治疗

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201480030418.5A Pending CN105555364A (zh) 2013-04-09 2014-04-09 炎症性眼科疾病的局部治疗

Country Status (11)

Country Link
US (2) US20160068527A1 (https=)
EP (2) EP2983713A1 (https=)
JP (2) JP2016516762A (https=)
CN (2) CN105431172A (https=)
AU (2) AU2014252808A1 (https=)
CA (2) CA2909111A1 (https=)
GB (2) GB2516137B (https=)
HK (2) HK1221166A1 (https=)
RU (2) RU2015145134A (https=)
WO (2) WO2014167326A1 (https=)
ZA (2) ZA201507718B (https=)

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