CN105412857A - Medicine for treating chilblain and preparation method thereof - Google Patents

Abstract

Chilblain often happens in winter and is caused when the local small artery of the skin of a patient suffering from chilblain shrinks during cold and damp weather or temperature changes suddenly for a long time, the artery blood vessel is paralyzed to expand, venous congestion is caused, and chilblain is caused due to poor local blood circulation. Red spots happen to local skin repeatedly, and tumescent injuries are caused. The medicine is prepared by combining perilla frutescens, aconitum carmichaelii, ginger, aconitum carmichaeli debx, fistular onion stalks, cinnamon, tamarix chinensis, dried ginger, mulberry leaves, asarum, fructus viticis, Chinese prickly ash, duckweed, alpinia officinarum hance, alpinia katsumadai, cloves, amomum cardamomum, black pepper, fructus amomi, fructus piperis longi, eupatorium fortunei, piper cubeba, agastache rugosa, fennel, mangnolia officinalis, evodia rutaecarpa, atractylodes lancea, fructus cnidii, radix clematidis, nidus vespae, clerodendrum trichotomum, paniculate swallowwort roots, caulis piperis futokadsurae and tourmaline. The medicine is combined, so that the functions of the medicine have a synergistic effect, and therefore chilblain can be effectively treated.

Description

A kind of medicine for the treatment of chilblain and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of chilblain and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Chilblain is common in winter, its pathogenic factor be chilblain patient skin run into cold, humidity or the changes in temperature sudden turn of events time, local small artery shrinks, arteries paralysis of a specified duration and expanding, venous congestion, and local blood circulation is bad and fall ill.Local skin is erythema, tumidus infringement repeatedly.Because current Western medicine cannot treat chilblain fast and effectively, therefore there is great demand in the Chinese medicine of people to rapid, effective treatment chilblain, up to now, also do not find about relevant report of the present invention.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment chilblain, thus completes the present invention.

Object of the present invention is just to provide a kind of Chinese medicine composition of effective treatment chilblain.

Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.

Medicine of the present invention selects Folium Perillae, Radix Aconiti Lateralis Preparata, Rhizoma Zingiberis Recens, Aconitum carmichjaelii Debx., Bulbus Allii Fistulosi, Cortex Cinnamomi, Ramulus et Folium Tamaricis, Rhizoma Zingiberis, Folium Mori, Herba Asari, Fructus Viticis, Pericarpium Zanthoxyli, Herba Spirodelae, Rhizoma Alpiniae Officinarum, Semen Alpiniae Katsumadai, Flos Caryophylli, Fructus Amomi Rotundus, Fructus Piperis, Fructus Amomi, Fructus Piperis Longi, Herba Eupatorii, Fructus Litseae, Herba Pogostemonis, Fructus Foeniculi, Cortex Magnoliae Officinalis, Fructus Evodiae, Rhizoma Atractylodis, Fructus Cnidii, Radix Clematidis, Nidus Vespae, Folium et Ramulus Clerodendri Trichotomi, Radix Cynanchi Paniculati, Caulis Piperis Kadsurae, tourmaline medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat chilblain.Folium Perillae is selected to be because its acrid in the mouth, temperature.Return lung, spleen channel.Function is induced sweat cold expelling, relieving QI stagnancy in the stomach.For anemofrigid cold, cough vomiting and nausea, vomiting during pregnancy, fish Eriocheir sinensis is poisoning.Radix Aconiti Lateralis Preparata is selected to be because its acrid in the mouth, sweet, hot greatly; Poisonous.GUIXIN, kidney, spleen channel.Function recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.Aconitum carmichjaelii Debx. is selected to be because its acrid in the mouth, heat, poisonous.To start with the moon, the shaoyin channel of fainting.Function dispelling cold and dampness, loose ailment said due to cold or exposure, warming the meridian, pain relieving, controls anemofrigid-damp arthralgia, severe and migratory arthralgia pain, spasm of the limbs, and hemiplegia, wind syndrome of head is had a headache, trusted subordinate's cold type of pain, carbuncle of yin nature toxic swelling.Cortex Cinnamomi is selected to be because its acrid in the mouth, sweet, hot greatly.Return kidney, spleen, the heart, Liver Channel.It is supporing yang that function mends fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.Ramulus et Folium Tamaricis is selected to be because its sweet-salty, flat.Enter lung, stomach, heart channel, function dispelling wind, induces sweat, diuresis, removing toxic substances.Control measles thoroughly difficult, rubella itching over the body, flu, cough with asthma, rheumatic ostalgia.Rhizoma Zingiberis is selected to be because its acrid in the mouth, heat.Return spleen, stomach, kidney, the heart, lung meridian.Function Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.Folium Mori are selected to be because its sweet in the mouth, hardship, cold.Return lung, Liver Channel.Function dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.Herba Asari is selected to be because its acrid in the mouth, temperature.GUIXIN, lung, kidney channel.Function expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.Select Fructus Viticis to be because its acrid in the mouth, hardship, be slightly cold.Return bladder, liver, stomach warp.Function dispelling wind and heat pathogens, the clear sharp head.For anemopyretic cold headache, gingivitis, the many tear of conjunctival congestion, poor vision, has a dizzy spell.Pericarpium Zanthoxyli is selected to be because its acrid in the mouth, temperature.Return spleen, stomach, kidney channel.Function warming middle-JIAO to relieve pain, killing parasites for relieving itching.For coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; External treatment eczema pruritus.Herba Spirodelae is selected to be because its acrid in the mouth, cold.Return lung meridian.Function dispelling wind-heat, rash, diuresis.For measles without adequate eruption, rubella pruritus, edema oliguria.Rhizoma Alpiniae Officinarum is selected to be because its acrid in the mouth, heat.Return spleen, stomach warp.Function warming stomach for dispelling cold, help digestion pain relieving.For coldness and pain in the epigastrium, gastrofrigid vomiting, belch acid regurgitation.Semen Alpiniae Katsumadai is selected to be because its acrid in the mouth, temperature.Return spleen, stomach warp.Function is drying damp and strengthening spleen, stomach warming preventing or arresting vomiting.For internal retention of cold wetness, distension and fullness in the abdomen cold type of pain, belch vomiting, anorexia.Flos Caryophylli is selected to be because its acrid in the mouth, temperature.Return spleen, stomach, lung, kidney channel.Function warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG.For Deficiency and coldness of spleen and stomach, singultus is vomitted, lack of appetite and vomiting, trusted subordinate's cold type of pain, impotence due to deficiency of the kidney.Fructus Amomi Rotundus is selected to be because its acrid in the mouth.Return lung; Liver; Stomach; Large intestine channel.The circulation of qi promoting of function cold expelling, invigorating the stomach and promoting digestion.Main abdominal distention; Accumulation of food in the stomach and intes tine due to indigestion; Lung cold cough selects Fructus Piperis to be because its acrid in the mouth, heat.Return stomach, large intestine channel.Function warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, expectorant.For gastrofrigid vomiting, stomachache is had loose bowels, inappetence, epilepsy abundant expectoration.Fructus Amomi is selected to be because its acrid in the mouth, temperature.Return spleen, stomach, kidney channel.Function removing dampness is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.Fructus Piperis Longi is selected to be because its acrid in the mouth, heat.Return stomach, large intestine channel.Function warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving.For coldness and pain in the epigastrium, vomiting, has loose bowels, migraine; External treatment is had a toothache.Herba Eupatorii is selected to be because its acrid in the mouth, flat.Return spleen, stomach, lung meridian.Function removing dampness by means of aromatics, appetizing of being amusing, delivers expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass vomiting and nausea, sweet greasy in mouth, halitosis, sialism, heat-damp in summer table disease, feeling of fullness in the head is uncomfortable in chest.Fructus Litseae is selected to be because its acrid in the mouth, temperature.Return spleen, stomach, kidney, urinary bladder channel.Function warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain.For cold syndrome of the stomach vomiting, coldness and pain in the epigastrium, colic of cold type is suffered from abdominal pain, stagnancy of cold-damp, turbid urine.Herba Pogostemonis is selected to be because its acrid in the mouth, tepor.Enter lung, spleen, stomach warp.The fast gas of function, and in, ward off dirty, damp eliminating.Cure cold heat-damp in summer, cold and heat, and headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.Fructus Foeniculi is selected to be because its acrid in the mouth, temperature.Return liver,kidney,spleen, stomach warp.Function dispersing cold for relieving pain, regulating qi-flowing for harmonizing stomach.For colic of cold type stomachache, the testis swelling and hanging down of either of the testes, dysmenorrhea, few abdomen cold type of pain, abdominal distention, lack of appetite and vomiting, hydrocele of testis.Salt Fructus Foeniculi warming the kidney dispersing cold for relieving pain.For colic of cold type stomachache, the testis swelling and hanging down of either of the testes, through cold stomachache.Cortex Magnoliae Officinalis is selected to be because its bitter in the mouth, pungent, temperature.Return spleen, stomach, lung, large intestine channel.The expectorant of function dampness, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.Fructus Evodiae is selected to be because its acrid in the mouth, hardship, heat; Slightly poisonous.Return liver, spleen, stomach, kidney channel.Function dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For headache due to JUE YIN disorder, colic of cold type is suffered from abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, vomiting acid regurgitation, Diarrhoea, external treatment aphtha; Hypertension.Rhizoma Atractylodis are selected to be because its acrid in the mouth, hardship, temperature.Return spleen, stomach, Liver Channel.Function is drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.Fructus Cnidii is selected to be because its acrid in the mouth, hardship, temperature; Slightly poisonous.Return kidney channel.Function warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus; Trichomonal vaginitis selects Radix Clematidis to be because its acrid in the mouth, salty, temperature.Return urinary bladder channel.Function expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.For rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone is choked with sobs larynx.Nidus Vespae is selected to be because it is sweet, flat, poisonous.Enter Yangming Channel.Function is dispeled the wind, counteracting toxic substances, parasite killing.Control infantile convulsion, migratory arthralgia, urticaria pruritus, acute mastitis, furunculosis, scrofula, anal fistula, acute toothache, tinea capitis, honeybee stings swollen pain.Folium et Ramulus Clerodendri Trichotomi is selected to be because its taste bitter, sweet, flat.Function remove rheumatism, blood pressure lowering.Root, leaf: rheumatic arthritis, hypertension, dysentery, malaria.Leaf: the tinea manuum is controlled in external, paddy-field dermatitis, eczema, hemorrhoid.Radix Cynanchi Paniculati is selected to be because its acrid in the mouth, temperature.Return liver, stomach warp.Function is dispeled the wind removing dampness, antalgesic-antipruritic.For rheumatic arthralgia, stomachache distension, toothache, lumbago, injury from falling down, urticaria, eczema.Caulis Piperis Kadsurae is selected to be because its acrid in the mouth, hardship, tepor.Return Liver Channel.Function wind-damp dispelling, the meridian dredging, stopping numbness pain.For anemofrigid-damp arthralgia, arthrodynia of extremities, the contracture of muscle arteries and veins, joint stuffiness.Select tourmaline to be because the crystal two ends meeting Accumulating charge of its tourmaline, produce electrical the two poles of the earth, produce the weak current suitable with the bioelectric current of human body.Tourmaline integrates " natural negative ion device ", " far infrared transmitter ", " cell activation teacher ", " blood vessel street cleaner ", " ecological water reorganizer ", numerous good reputation such as " life jewel ".Under the effect of pressure and heating power, permanently to launch the useful wavelength of human body at 4-14 micron far infrared, discharge a large amount of anion.So to health important role.

Detailed description of the invention

The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:

folium Perillae	5-15 grams	rhizoma Alpiniae Officinarum	3-13 grams	cortex Magnoliae Officinalis	3-13 grams
						radix Aconiti Lateralis Preparata	3-15 grams	semen Alpiniae Katsumadai	3-13 grams	fructus Evodiae	3-12 grams
aconitum carmichjaelii Debx.	2-12 grams	flos Caryophylli	1-7 grams	rhizoma Atractylodis	3-13 grams
						cortex Cinnamomi	3-12 grams	fructus Amomi Rotundus	3-12 grams	fructus Cnidii	3-13 grams
ramulus et Folium Tamaricis	3-13 grams	fructus Piperis	1-7 grams	radix Clematidis	6-15 grams
						rhizoma Zingiberis	3-12 grams	fructus Amomi	3-12 grams	nidus Vespae	3-13 grams
folium Mori	5-13 grams	fructus Piperis Longi	3-12 grams	folium et Ramulus Clerodendri Trichotomi	5-15 grams
						herba Asari	1-7 grams	herba Eupatorii	3-12 grams	radix Cynanchi Paniculati	3-15 grams
fructus Viticis	5-13 grams	fructus Litseae	1-7 grams	caulis Piperis Kadsurae	6-15 grams
						pericarpium Zanthoxyli	3-12 grams	herba Pogostemonis	5-15 grams	tourmaline	15-50 grams
herba Spirodelae	3-12 grams	fructus Foeniculi	3-12 grams.

Be preferably:

folium Perillae	13 grams	rhizoma Alpiniae Officinarum	12 grams	cortex Magnoliae Officinalis	12 grams
						radix Aconiti Lateralis Preparata	13 grams	semen Alpiniae Katsumadai	12 grams	fructus Evodiae	12 grams
aconitum carmichjaelii Debx.	12 grams	flos Caryophylli	7 grams	rhizoma Atractylodis	12 grams
						cortex Cinnamomi	12 grams	fructus Amomi Rotundus	12 grams	fructus Cnidii	12 grams
ramulus et Folium Tamaricis	12 grams	fructus Piperis	6 grams	radix Clematidis	12 grams
						rhizoma Zingiberis	11 grams	fructus Amomi	12 grams	nidus Vespae	12 grams
folium Mori	12 grams	fructus Piperis Longi	12 grams	folium et Ramulus Clerodendri Trichotomi	13 grams
						herba Asari	7 grams	herba Eupatorii	12 grams	radix Cynanchi Paniculati	13 grams
fructus Viticis	13 grams	fructus Litseae	7 grams	caulis Piperis Kadsurae	13 grams
						pericarpium Zanthoxyli	12 grams	herba Pogostemonis	13 grams	tourmaline	50 grams
herba Spirodelae	12 grams	fructus Foeniculi	12 grams.

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Folium Perillae: this product is the dried leaves (or band twig) of labiate Folium Perillae.Gather when summer, branch and leaf were luxuriant, remove impurity and always obstruct; Or spray clear water, chopping, dry;

2, Radix Aconiti Lateralis Preparata: this product is the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx..Late June excavated to early August, and removing parent root, fibrous root and silt, practise and claim " mud Radix Aconiti Lateralis Preparata ", be processed into following kinds;

3, Aconitum carmichjaelii Debx.: be the tuber of ranunculaceae plant Aconitum carmichjaelii Debx. (cultivation product).Dig out Herb between the Summer Solstice to Slight Heat, removing overground part stem and leaf, then takes daughter root, separates with parent root, pick decontamination, cleans ash bits, dries;

4, Cortex Cinnamomi: this product is the dry bark of canella Cortex Cinnamomi.Strip more than autumn, removing impurity and rough bark.Used time smashs to pieces;

5, Ramulus et Folium Tamaricis: the delicate branch and leaf being Tamaricaceae Ramulus et Folium Tamaricis, tamarix juniperina Bunge or Tamarix ramosissima.When 4 ~ May, flower was not opened, folding gets delicate branch and leaf, picks decontamination, destemming, and cutting after spray profit, dries;

6, Rhizoma Zingiberis: this product is the dry rhizome of zingiber.Winter excavates, removing fibrous root and silt, slightly bubble, cleans, runs through, cut sheet or block, dry;

7, Folium Mori: this product is the dried leaves of moraceae plants Mulberry.Gather after first frost, removing impurity, rubs with the hands broken, removes handle, sieve dedust bits;

8, Herba Asari: summer fructescence or excavate early autumn, removing impurity, spray clear water, slightly moistens, cutting, dries in the shade;

9, Fructus Viticis: gather during fruit maturation in autumn, removing impurity, dries;

10, Pericarpium Zanthoxyli: mature fruit of gathering autumn, removes impurity and dries.Separate for subsequent use with seed;

11, Herba Spirodelae: this product is the dry herb of plant and of its applications duckweed.6 ~ JIUYUE is gathered, and cleans, and removing impurity, dries;

12, Rhizoma Alpiniae Officinarum: this product is the dry rhizome of zingiberaceous plant Rhizoma Alpiniae Officinarum.Excavate at the beginning of autumn late summer, removing impurity, cleans, runs through, shave, dry;

13, Semen Alpiniae Katsumadai: this product is the dry near mature seed of zingiberaceous plant Semen Alpiniae Katsumadai.Summer, Qiu Erji gather, and shine to ninety percent dry, or slightly scald with water, shine to half-dried, and removing peel, takes out seed group, dry.Used time smashs to pieces;

14, Flos Caryophylli: this product is the dry flower of plant clove of myrtaceae.Pluck when alabastrum turns red by green, dry, removing impurity, sieve dedust bits.Used time smashs to pieces;

15, Fructus Amomi Rotundus: be the seed of lid section plant Fructus Amomi subulati.Fruit is gathered during maturation, cuts infructescence, and removing impurity, dries;

16, Fructus Piperis: this product is the nearly ripe or mature fruit of the drying of Piperaceae plant Fructus Piperis.Autumn Mo gathers when time the spring, fruit was dirty-green, dries.Removing impurity and ash bits.Used time is ground into fine powder;

17, Fructus Amomi: gather during fruit maturation between summer, autumn, dries or cold drying.Used time smashs to pieces;

18, Fructus Piperis Longi: this product is the nearly ripe or mature fruit cluster of the drying of Piperaceae plant Fructus Piperis Longi.Fruit ear is gathered by during green blackening, and removing impurity, dries.Used time smashs to pieces;

19, Herba Eupatorii: this product is the dry aerial parts of feverfew Herba Eupatorii.Summer, Qiu Erji tap at twice, and removing impurity, cleans, slightly moisten, cutting, dry;

20, Fructus Litseae: this product is the dry mature fruit of canella cubeb litsen tree.Gather during fruit maturation in autumn, removing impurity, dries;

21, gather autumn, pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even;

22, Fructus Foeniculi: this product is the dry mature fruit of samphire Fructus Foeniculi; Its root, leaf and herb are also pharmaceutically acceptable.Autumn taps plant when fruit is first ripe, dries, lays fruit, removing impurity.Herb and Ye Xiaqiukecai, the root four seasons can adopt, and wash away earth, dry;

23, Cortex Magnoliae Officinalis: strip root bark and branch skin 4 ~ June, scrape off rough bark, cleans, runs through, shredding, dry;

24, Fructus Evodiae: when 8 ~ November, fruit not yet ftractureed, cut Fruit branch, dries or cold drying, except impurity such as debranching, leaf, carpopodiums;

25, Rhizoma Atractylodis: spring, Qiu Erji excavate, removing impurity, cleans, runs through, chip drying;

26, Fructus Cnidii: this product is the dry mature fruit of samphire cnidium monnieri.Gather when summer, autumn two season fruit maturation, removing impurity, dries;

27, Radix Clematidis: autumn excavates, removing impurity, cleans, runs through, cutting, dry;

28, Nidus Vespae: be the nest of Vespidae insecticide hornet.Adopt after, clean, steam thoroughly, be cut into small pieces, dry; Or slightly fry to micro-yellow.Forge Nidus Vespae: get Nidus Vespae fragment and enter in tank, brine sludge sealing, forges sustainability, dew releasing fire-toxin;

29, Folium et Ramulus Clerodendri Trichotomi: Verbena officinalis Ke Cheng paulownia platymiscium clerodendron trichotomum, is used as medicine with root, stem, leaf.Adopt root and stem spring and autumn, picking leaves before blooming, dries;

30, Radix Cynanchi Paniculati is selected to be because its this product is the dry root and rhizome of asclepiadaceae Cynanchum plant Radix Cynanchi Paniculati.Autumn excavates, and removing impurity, cleans rapidly, cutting, dry in the shade;

31, Caulis Piperis Kadsurae: this product is the dry rattan of Piperaceae plant Radix seu Caulis fici Martinii.Summer, Qiu Erji tap, and removing root, leaf, dry.Removing impurity, soaks, runs through, cut sheet, dry;

32, tourmaline: a kind of mineral, glassy lustre, hardness 7-8, has the color variety such as blueness, green, has transparent, also has opaque;

Two, prepare

1, by the Folium Perillae of described weight, Radix Aconiti Lateralis Preparata, Rhizoma Zingiberis Recens, Aconitum carmichjaelii Debx., Bulbus Allii Fistulosi, Cortex Cinnamomi, Ramulus et Folium Tamaricis, Rhizoma Zingiberis, Folium Mori, Herba Asari, Fructus Viticis, Pericarpium Zanthoxyli, Herba Spirodelae, Rhizoma Alpiniae Officinarum, Semen Alpiniae Katsumadai, Flos Caryophylli, Fructus Amomi Rotundus, Fructus Piperis, Fructus Amomi, Fructus Piperis Longi, Herba Eupatorii, Fructus Litseae, Herba Pogostemonis, Fructus Foeniculi, Cortex Magnoliae Officinalis, Fructus Evodiae, Rhizoma Atractylodis, Fructus Cnidii, Radix Clematidis, Nidus Vespae, Folium et Ramulus Clerodendri Trichotomi, Radix Cynanchi Paniculati, Caulis Piperis Kadsurae, tourmaline fine grinding through superfine sieved consider to obtain impalpable powder bottling preserve;

Medicated powder is taken to apply with in chilblain when 2, meeting chilblain.

Medicine of the present invention has blood circulation promoting and blood stasis dispelling, yang invigorating expelling pathogenic factors from muscles, the function that cold expelling dispels the wind, and is used for the treatment of chilblain instant effect, good effect, does not recur.

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.

The animal toxicity test of [test example 1] medicine of the present invention

Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25g/kg, and normal amount is 10g/kg, administering mode be the drug of topical application in body surface, every day 1 time, be used in conjunction 5 days, observe administration reaction every day, result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1, physical data

Accept chilblain patient totally 36 examples for medical treatment.

2, diagnostic criteria

Chilblain is apt to occur in early winter, early spring, and with child, women and peripheral blood circulation, bad person is common, the performances such as these patients often send out cool with acral body skin, acrocyanosis, hyperhidrosis.Skin lesion is apt to occur in the places such as finger, the back of the hand, face, auricle, toes, sufficient edge, heel, the distribution of normal both sides.Common infringement is the edematous erythema of the congestive dark violet redness protuberance of limitation, and indefinite border, edge is cerise, and surface is nervous glossy, and matter is soft.Local pressing can be faded, and goes to press rear redness to recover gradually.

3, Therapeutic Method

Select above-mentioned medicament, use to patient, once a day, apply chilblain medicine at every turn, use 2 days continuously.

4, efficacy assessment standard

Effective: chilblain symptom is fully recovered, recover normal.

Take a turn for the better: chilblain symptom alleviates, and progressively takes a turn for the better.

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form):

In above-mentioned treatment, by Drug therapy chilblain patient 36 example of the present invention, effective 33 examples of result, obvious effective rate is 91.67%, and take a turn for the better 2 examples, and improvement rate is 5.55%, and invalid 1 example, total effective rate is 97.22%.

Claims (3)

1. treat a medicine for chilblain, it is characterized in that: it is made up of the crude drug in following weight range:

folium Perillae 5-15 grams rhizoma Alpiniae Officinarum 3-13 grams cortex Magnoliae Officinalis 3-13 grams radix Aconiti Lateralis Preparata 3-15 grams semen Alpiniae Katsumadai 3-13 grams fructus Evodiae 3-12 grams aconitum carmichjaelii Debx. 2-12 grams flos Caryophylli 1-7 grams rhizoma Atractylodis 3-13 grams cortex Cinnamomi 3-12 grams fructus Amomi Rotundus 3-12 grams fructus Cnidii 3-13 grams ramulus et Folium Tamaricis 3-13 grams fructus Piperis 1-7 grams radix Clematidis 6-15 grams rhizoma Zingiberis 3-12 grams fructus Amomi 3-12 grams nidus Vespae 3-13 grams folium Mori 5-13 grams fructus Piperis Longi 3-12 grams folium et Ramulus Clerodendri Trichotomi 5-15 grams herba Asari 1-7 grams herba Eupatorii 3-12 grams radix Cynanchi Paniculati 3-15 grams fructus Viticis 5-13 grams fructus Litseae 1-7 grams caulis Piperis Kadsurae 6-15 grams pericarpium Zanthoxyli 3-12 grams herba Pogostemonis 5-15 grams tourmaline 15-50 grams herba Spirodelae 3-12 grams fructus Foeniculi 3-12 grams.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

folium Perillae 13 grams rhizoma Alpiniae Officinarum 12 grams cortex Magnoliae Officinalis 12 grams radix Aconiti Lateralis Preparata 13 grams semen Alpiniae Katsumadai 12 grams fructus Evodiae 12 grams aconitum carmichjaelii Debx. 12 grams flos Caryophylli 7 grams rhizoma Atractylodis 12 grams cortex Cinnamomi 12 grams fructus Amomi Rotundus 12 grams fructus Cnidii 12 grams ramulus et Folium Tamaricis 12 grams fructus Piperis 6 grams radix Clematidis 12 grams rhizoma Zingiberis 11 grams fructus Amomi 12 grams nidus Vespae 12 grams folium Mori 12 grams fructus Piperis Longi 12 grams folium et Ramulus Clerodendri Trichotomi 13 grams herba Asari 7 grams herba Eupatorii 12 grams radix Cynanchi Paniculati 13 grams fructus Viticis 13 grams fructus Litseae 7 grams caulis Piperis Kadsurae 13 grams pericarpium Zanthoxyli 12 grams herba Pogostemonis 13 grams tourmaline 50 grams herba Spirodelae 12 grams fructus Foeniculi 12 grams.

3. the medicine according to right 1 or 2, is characterized in that: it comprises the following steps:

One, get the raw materials ready

1, Folium Perillae: this product is the dried leaves (or band twig) of labiate Folium Perillae.Gather when summer, branch and leaf were luxuriant, remove impurity and always obstruct; Or spray clear water, chopping, dry.

2, Radix Aconiti Lateralis Preparata: this product is the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx..Late June excavated to early August, and removing parent root, fibrous root and silt, practise and claim " mud Radix Aconiti Lateralis Preparata ", be processed into following kinds.

3, Aconitum carmichjaelii Debx.: be the tuber of ranunculaceae plant Aconitum carmichjaelii Debx. (cultivation product).Dig out Herb between the Summer Solstice to Slight Heat, removing overground part stem and leaf, then takes daughter root, separates with parent root, pick decontamination, cleans ash bits, dries.

4, Cortex Cinnamomi: this product is the dry bark of canella Cortex Cinnamomi.Strip more than autumn, removing impurity and rough bark.Used time smashs to pieces.

5, Ramulus et Folium Tamaricis: the delicate branch and leaf being Tamaricaceae Ramulus et Folium Tamaricis, tamarix juniperina Bunge or Tamarix ramosissima.When 4 ~ May, flower was not opened, folding gets delicate branch and leaf, picks decontamination, destemming, and cutting after spray profit, dries.

6, Rhizoma Zingiberis: this product is the dry rhizome of zingiber.Winter excavates, removing fibrous root and silt, slightly bubble, cleans, runs through, cut sheet or block, dry.

7, Folium Mori: this product is the dried leaves of moraceae plants Mulberry.Gather after first frost, removing impurity, rubs with the hands broken, removes handle, sieve dedust bits.

8, Herba Asari: summer fructescence or excavate early autumn, removing impurity, spray clear water, slightly moistens, cutting, dries in the shade.

9, Fructus Viticis: gather during fruit maturation in autumn, removing impurity, dries.

10, Pericarpium Zanthoxyli: mature fruit of gathering autumn, removes impurity and dries.Separate for subsequent use with seed.

11, Herba Spirodelae: this product is the dry herb of plant and of its applications duckweed.6 ~ JIUYUE is gathered, and cleans, and removing impurity, dries.

12, Rhizoma Alpiniae Officinarum: this product is the dry rhizome of zingiberaceous plant Rhizoma Alpiniae Officinarum.Excavate at the beginning of autumn late summer, removing impurity, cleans, runs through, shave, dry

13, Semen Alpiniae Katsumadai: this product is the dry near mature seed of zingiberaceous plant Semen Alpiniae Katsumadai.Summer, Qiu Erji gather, and shine to ninety percent dry, or slightly scald with water, shine to half-dried, and removing peel, takes out seed group, dry.Used time smashs to pieces.

14, Flos Caryophylli: this product is the dry flower of plant clove of myrtaceae.Pluck when alabastrum turns red by green, dry, removing impurity, sieve dedust bits.Used time smashs to pieces.

15, Fructus Amomi Rotundus: be the seed of lid section plant Fructus Amomi subulati.Fruit is gathered during maturation, cuts infructescence, and removing impurity, dries.

16, Fructus Piperis: this product is the nearly ripe or mature fruit of the drying of Piperaceae plant Fructus Piperis.Autumn Mo gathers when time the spring, fruit was dirty-green, dries.Removing impurity and ash bits.Used time is ground into fine powder.

17, Fructus Amomi: gather during fruit maturation between summer, autumn, dries or cold drying.Used time smashs to pieces.

18, Fructus Piperis Longi: this product is the nearly ripe or mature fruit cluster of the drying of Piperaceae plant Fructus Piperis Longi.Fruit ear is gathered by during green blackening, and removing impurity, dries.Used time smashs to pieces.

19, Herba Eupatorii: this product is the dry aerial parts of feverfew Herba Eupatorii.Summer, Qiu Erji tap at twice, and removing impurity, cleans, slightly moisten, cutting, dry.

20, Fructus Litseae: this product is the dry mature fruit of canella cubeb litsen tree.Gather during fruit maturation in autumn, removing impurity, dries.

21, gather autumn, pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even.

22, Fructus Foeniculi: this product is the dry mature fruit of samphire Fructus Foeniculi; Its root, leaf and herb are also pharmaceutically acceptable.Autumn taps plant when fruit is first ripe, dries, lays fruit, removing impurity.Herb and Ye Xiaqiukecai, the root four seasons can adopt, and wash away earth, dry.

23, Cortex Magnoliae Officinalis: strip root bark and branch skin 5 ~ June, scrape off rough bark, cleans, runs through, shredding, dry.

24, Fructus Evodiae: when 8 ~ November, fruit not yet ftractureed, cut Fruit branch, dries or cold drying, except impurity such as debranching, leaf, carpopodiums.

25, Rhizoma Atractylodis: spring, Qiu Erji excavate, removing impurity, cleans, runs through, chip drying;

26, Fructus Cnidii: this product is the dry mature fruit of samphire cnidium monnieri.Gather when summer, autumn two season fruit maturation, removing impurity, dries.

27, Radix Clematidis: autumn excavates, removing impurity, cleans, runs through, cutting, dry.

28, Nidus Vespae: be the nest of Vespidae insecticide hornet.Adopt after, clean, steam thoroughly, be cut into small pieces, dry; Or slightly fry to micro-yellow.

29, Folium et Ramulus Clerodendri Trichotomi: Verbena officinalis Ke Cheng paulownia platymiscium clerodendron trichotomum, is used as medicine with root, stem, leaf.Adopt root and stem spring and autumn, picking leaves before blooming, dries.

30, Radix Cynanchi Paniculati is selected to be because its this product is the dry root and rhizome of asclepiadaceae Cynanchum plant Radix Cynanchi Paniculati.Autumn excavates, and removing impurity, cleans rapidly, cutting, dry in the shade.

31, Caulis Piperis Kadsurae: this product is the dry rattan of Piperaceae plant Radix seu Caulis fici Martinii.Summer and autumn gathers, and removing impurity, soaks, run through, cut sheet, dry.

32, tourmaline: a kind of mineral, glassy lustre, hardness 7-8, has the color variety such as blueness, green, has transparent, also has opaque.

Two, prepare

1, by the Folium Perillae of described weight, Radix Aconiti Lateralis Preparata, Rhizoma Zingiberis Recens, Aconitum carmichjaelii Debx., Bulbus Allii Fistulosi, Cortex Cinnamomi, Ramulus et Folium Tamaricis, Rhizoma Zingiberis, Folium Mori, Herba Asari, Fructus Viticis, Pericarpium Zanthoxyli, Herba Spirodelae, Rhizoma Alpiniae Officinarum, Semen Alpiniae Katsumadai, Flos Caryophylli, Fructus Amomi Rotundus, Fructus Piperis, Fructus Amomi, Fructus Piperis Longi, Herba Eupatorii, Fructus Litseae, Herba Pogostemonis, Fructus Foeniculi, Cortex Magnoliae Officinalis, Fructus Evodiae, Rhizoma Atractylodis, Fructus Cnidii, Radix Clematidis, Nidus Vespae, Folium et Ramulus Clerodendri Trichotomi, Radix Cynanchi Paniculati, Caulis Piperis Kadsurae, tourmaline fine grinding through superfine sieved consider to obtain impalpable powder bottling preserve;

Medicated powder is taken to apply with in chilblain when 2, meeting chilblain.