CN105396027A - Medicine for treating male infertility and preparation method thereof - Google Patents

Abstract

The invention provides medicine for treating male infertility and a preparation method thereof. Male infertility refers to infertility caused by male elements, aetiological agents of the disease are complex, and plenty of diseases or elements can cause male infertility. Clinically, male infertility is categorized into sexual dysfunction and normal sexual function, and the normal sexual function condition can be further divided into such symptoms as azoospermatism, oligospermia, asthenozoospermia and asthenospermia. The medicine is prepared by combining cynomorium coccineum, corn cervi pantotrichum, yam rhizomes, human placenta, white atractylodes rhizome, vigna umbellata, radix angelica sinensis, morinda officinalis, rush, epimedium herbs, rhizoma cibotii, fructus psoraleae, fructus alpiniae oxyphyllae, flatstem milkvetch seeds, exocarpium benincasae, actinolite, polygonum multiflorum, adenophora roots, dendrobe, semen allii tuberosi, sealwort, Chinese wolfberry fruits, mulberries, glossy privet fruits, black sesame, seal penes, prepared rehmannia roots, cistanche, gekko, radix paeoniae alba, lily, radix ophiopogonis and radix polygonati officinalis. All drugs are combined, so that all the drugs achieve a synergistic effect in efficacy, and thereby male infertility can be effectively treated.

Description

A kind of medicine for the treatment of male infertility and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of male infertility and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Male infertility refer to due to male factor cause sterile, the pathogenic factor of primary disease is complicated, and a lot of disease or factor all can cause male sterility.Clinically male sterility is divided into sexual dysfunction and normal two classes of sexual function, sexual function normal condition can be further divided into the symptoms such as azoospermia, oligospermatism azoospermia, asthenospermia disease, because current Western medicine cannot treat male infertility fast and effectively, therefore there is great demand in the Chinese medicine of people to rapid, effective treatment male infertility, up to now, also do not find about relevant report of the present invention.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment male infertility, thus completes the present invention.

Object of the present invention is just to provide a kind of Chinese medicine composition of effective treatment male infertility.

Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.

Medicine of the present invention selects Herba Cynomorii, Cornu Cervi Pantotrichum, Rhizoma Dioscoreae Septemlobae, Placenta Hominis, the Rhizoma Atractylodis Macrocephalae, Semen Phaseoli, Radix Angelicae Sinensis, Radix Morindae Officinalis, Medulla Junci, Herba Epimedii, Rhizoma Cibotii, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Astragali Complanati, Exocarpium Benincasae, Actinolitum, Radix Polygoni Multiflori, Radix Adenophorae (Radix Glehniae), Herba Dendrobii, Semen Allii Tuberosi, Rhizoma Polygonati, Fructus Lycii, Fructus Mori, Fructus Ligustri Lucidi, Semen Sesami Nigrum, the penis and tester of an ursine seal, Radix Rehmanniae Preparata, Herba Cistanches, Gecko, Radix Paeoniae Alba, Bulbus Lilii, Radix Ophiopogonis, Rhizoma Polygonati Odorati medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat male infertility.Herba Cynomorii is wherein selected to be because its sweet in the mouth, temperature.Return spleen, kidney, large intestine channel.Function kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.Soft for waist knee joint flaccidity, sexual impotence spermatorrhea, dryness of the intestine constipation.Cornu Cervi Pantotrichum is selected to be because its sweet in the mouth, salty, temperature.Return kidney, Liver Channel.Function invigorating kidney-YANG, benefiting essence-blood, bone and muscle strengthening, adjusts punching to appoint, holder sore.For sexual impotence spermatorrhea, cold womb is infertile, weakness and emaciation, Mental fatigue, fear of cold, and vertigo and tinnitus is deaf, spinal column cold type of pain, and muscles and bones flaccidity is soft, bleeding not during menses; Rhizoma Dioscoreae Septemlobae is selected to be because its bitter in the mouth, flat.Enter liver, stomach, urinary bladder channel.Function is dispeled the wind, dampness removing.Dispelling the wind and dampness pathogens insensitive impediment, lumbocrural pain, dysuria, stranguria with turbid discharge, seminal emission, damp and hot sore.Placenta Hominis is selected to be because its sweet in the mouth, salty, temperature.GUIXIN, lung, kidney channel.Function the kidney warming mends essence, benefiting QI and nourishing blood.For asthenia weakness and emaciation, hectic fever due to YIN-deficiency night sweat, cough and asthma, lack of appetite is breathed hard, impotence and seminal emission, infertile hypogalactia.

The Rhizoma Atractylodis Macrocephalae is selected to be because its bitter in the mouth, sweet, temperature.Return spleen, stomach warp.Function invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.

Semen Phaseoli is selected to be because of its sweet in the mouth, acid, flat.GUIXIN, small intestine meridian.Function inducing diuresis to remove edema, removing toxic substances and promoting pus discharge.For edema distension, beriberi limb swells, jaundice dark coloured urine, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.Radix Angelicae Sinensis is selected to be because its taste sweet, acrid, warm.Return liver, the heart, spleen channel.Function is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.Radix Morindae Officinalis is selected to be because its sweet in the mouth, pungent, tepor.Return kidney, Liver Channel.Function kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.Select Medulla Junci to be because its sweet in the mouth, light, be slightly cold.GUIXIN, lung, small intestine meridian.Function clearing away heart-fire, diuresis.For vexed insomnia, the puckery pain of oliguria, aphtha of the mouth and tongue.Herba Epimedii is selected to be because its taste acrid, sweet, warm.Return liver, kidney channel.Function kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.Rhizoma Cibotii is selected to be because its bitter in the mouth, sweet, temperature.Return liver, kidney channel.Function invigorating the liver and kidney, strong spinal column, wind-damp dispelling.For soreness of the waist and knees, weakness of the lower extremities, rheumatic arthralgia.Fructus Psoraleae is selected to be because its acrid in the mouth, hardship, temperature.Return kidney, spleen channel.Function warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.Fructus Alpiniae Oxyphyllae is selected to be because its acrid in the mouth, temperature.Enter spleen, kidney channel.Function warming the spleen, warming the kidney, solid and gas, arresting seminal emission.Control cold air stomachache, invasion by pathogenic cold vomit and diarrhoea, many salivas, seminal emission, dribbling urination, night many urine.Radix Adenophorae (Radix Glehniae) is selected to be because its sweet in the mouth, cool.Function clearing away heat and nourishing YIN, nourishing the lung to arrest cough.Cure mainly tracheitis, pertussis, cough due to lung-heat, cough up phlegm yellow thick; Radix Polygoni Multiflori is selected to be because its bitter in the mouth, sweet, puckery, temperature.Return liver, the heart, kidney channel.Function is detoxified, eliminating carbuncle, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia.Semen Astragali Complanati is selected to be because its sweet in the mouth, temperature.Return liver, kidney channel.Function temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs, reducing urination, improving eyesight.For lumbago due to renal deficiency, seminal emission premature ejaculation, nebulousurine leukorrhagia, dribbling urination, dizzy blurred vision.Exocarpium Benincasae is selected to be because its sweet in the mouth, cool.Return spleen, small intestine meridian.Function inducing diuresis to remove edema.For edema distension, dysuria, summer-heat is thirsty, oliguria with reddish urine.Actinolitum is selected to be because its salty in the mouth, tepor.Function the kidney invigorating, tonifying YANG.For sexual impotence erectile problem, the cold numbness of waist knee joint, limbs are fainted cold, uterus cold caused by deficiency, menoxenia.Select Herba Dendrobii to be because its sweet in the mouth, be slightly cold.Return stomach, kidney channel.Function reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.Semen Allii Tuberosi is selected to be because its taste acrid, sweet, warm.Return liver, kidney channel.Function temperature compensation Liver and kidney, tonifying YANG controlling nocturnal emission with astringent drugs.For impotence and seminal emission, soreness of waist and knee joint, enuresis frequent micturition, nebulousurine leukorrhagia.Rhizoma Polygonati is selected to be because its sweet in the mouth, flat.Return spleen, lung, kidney channel.Function boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.Rhizoma Cibotii is selected to be because its sweet in the mouth, flat.Return liver, kidney channel.Function tonification Liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.Fructus Mori are selected to be because of its sweet in the mouth, acid, cold.GUIXIN, liver, kidney channel.Function is enriched blood YIN nourishing, promotes the production of body fluid and moisturizes.For vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.Fructus Ligustri Lucidi is selected to be because its taste sweet, bitter, cold.Return liver, kidney channel.Function tonification Liver and kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.Semen Sesami Nigrum is selected to be because its sweet in the mouth, flat.Return liver, kidney, large intestine channel.Function invigorating the liver and kidney, benefiting essence-blood, intestine moistening is dry.For dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation; The penis and tester of an ursine seal is selected to be because its warming the kidney, tonifying YANG, benefit essence.Cure mainly kidney portion weak, impotence and seminal emission, waist knee flaccidity is unable; Radix Rehmanniae Preparata is selected to be because its sweet in the mouth, tepor.Return liver, kidney channel.Function nourishing YIN and supplementing blood, beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair; Herba Cistanches is selected to be because its sweet in the mouth, salty, temperature.Return kidney, large intestine channel.Function kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.For sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation.Gecko is selected to be because its salty in the mouth, flat.Return lung, kidney channel.Function invigorating the lung and the kidney, improving inspiration by invigorating kidney-QI Dingchuan, supporing yang benefit essence.For dyspnea due to deficiency tachypnea, chronic cough hemoptysis; Select Radix Paeoniae Alba to be because of its bitter in the mouth, acid, be slightly cold.Return liver, spleen channel.The pain relieving of function suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.Bulbus Lilii is selected to be because its sweet in the mouth, cold.GUIXIN, lung meridian.Function nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.Select be that micro-hardship, is slightly cold because its sweet in the mouth Radix Ophiopogonis.GUIXIN, lung, stomach warp.Function YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.Select Rhizoma Polygonati Odorati to be because its sweet in the mouth, be slightly cold.Attach to the lung and stomach meridians.Function nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.For lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.

Detailed description of the invention

The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:

herba Cynomorii	5-15 grams	rhizoma Cibotii	6-15 grams	rhizoma Polygonati	9-15 grams
						cornu Cervi Pantotrichum	1-5 grams	fructus Psoraleae	6-13 grams	fructus Lycii	6-12 grams
rhizoma Dioscoreae Septemlobae	11-18 grams	fructus Alpiniae Oxyphyllae	3-15 grams	fructus Mori	9-15 grams
						placenta Hominis	1-5 grams	radix Polygoni Multiflori	6-15 grams	fructus Ligustri Lucidi	6-17 grams
the Rhizoma Atractylodis Macrocephalae	6-15 grams	radix Adenophorae (Radix Glehniae)	7-15 grams	semen Sesami Nigrum	9-15 grams
						semen Phaseoli	9-30 grams	semen Astragali Complanati	9-15 grams	the penis and tester of an ursine seal	3-13 grams
radix Angelicae Sinensis	6-13 grams	exocarpium Benincasae	9-30 grams	radix Rehmanniae Preparata	9-15 grams
						radix Morindae Officinalis	3-13 grams	actinolitum	3-8 grams	herba Cistanches	6-12 grams
medulla Junci	1-7 grams	herba Dendrobii	6-12 grams	gecko	3-12 grams
						herba Epimedii	3-13 grams	semen Allii Tuberosi	3-13 grams	radix Paeoniae Alba	6-15 grams
bulbus Lilii	6-15 grams	radix Ophiopogonis	6-15 grams	rhizoma Polygonati Odorati	6-13 grams.

Be preferably:

herba Cynomorii	13 grams	rhizoma Cibotii	13 grams	rhizoma Polygonati	15 grams
						cornu Cervi Pantotrichum	3 grams	fructus Psoraleae	12 grams	fructus Lycii	12 grams
rhizoma Dioscoreae Septemlobae	17 grams	fructus Alpiniae Oxyphyllae	13 grams	fructus Mori	13 grams
						placenta Hominis	3 grams	radix Polygoni Multiflori	13 grams	fructus Ligustri Lucidi	13 grams
the Rhizoma Atractylodis Macrocephalae	12 grams	radix Adenophorae (Radix Glehniae)	15 grams	semen Sesami Nigrum	13 grams
						semen Phaseoli	25 grams	semen Astragali Complanati	15 grams	the penis and tester of an ursine seal	11 grams
radix Angelicae Sinensis	13 grams	exocarpium Benincasae	25 grams	radix Rehmanniae Preparata	13 grams
						radix Morindae Officinalis	12 grams	actinolitum	7 grams	herba Cistanches	12 grams
medulla Junci	5 grams	herba Dendrobii	12 grams	gecko	12 grams
						herba Epimedii	12 grams	semen Allii Tuberosi	13 grams	radix Paeoniae Alba	13 grams
bulbus Lilii	13 grams	radix Ophiopogonis	13 grams	rhizoma Polygonati Odorati	13 grams.

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready:

1, Herba Cynomorii: this product is the dry meat stem of Cynomoriaceae plant Herba Cynomorii.Spring excavates, and removing inflorescence, cleans, run through, shave, dry.

2, Cornu Cervi Pantotrichum: Cornu Cervi Pantotrichum got by summer, Qiu Erji saw, after processing, dries.Get Cornu Cervi Pantotrichum, burn remove floss, scraping, with the fine and soft body of Fabric tape winding, from saw kerf face, aperture pours into hot Chinese liquor, and constantly freshens the drink, and slightly steams, transection sheet to running through or fill with wine, flattens, dry.

3, Rhizoma Dioscoreae Septemlobae: spring, Qiu Junke excavate.Dig out afterwash removing fibrous root, section is dried.

4, the penis and tester of an ursine seal: this product is the dry Placenta Hominis of Healthy People.Fresh human placenta being removed amniotic membrane and umbilical cord, repeatedly rinsing to removing blood, steam or put in boiling water and steam thoroughly, dry, except dedust bits, pound into fritter or be ground into fine powder.

5, the Rhizoma Atractylodis Macrocephalae: excavate when withered and yellow, the upper leaf of inferior leads in winter becomes fragile, removing silt, dries or dries, then remove fibrous root.

6, Semen Phaseoli: autumn fruit maturation and do not ftracture time to choose Herb, dry, lay seed, removing impurity, then dry.

7, Radix Angelicae Sinensis: this product is the dry root of umbelliferae angelica.Autumn end gathers, and removing impurity, cleans, run through, shave, dry or cold drying.

8, Radix Morindae Officinalis: this product is the dry root of Maguireothamnus speciosus Radix Morindae Officinalis.The whole year all can excavate, and cleans, gets Radix Morindae Officinalis, steams thoroughly, remove core while hot, cutting according to steaming method, dry.

9, Medulla Junci: this product is the dry stem pith of rush family plant Medulla Junci.Late summer extracts stem to autumn, dries, and takes out stem pith, removing impurity, the section of cutting.

10, Herba Epimedii: tap when summer, autumn, stem and leaf was luxuriant, the thick stalk of removing and impurity, removing impurity, wins blade, and spray clear water, slightly moistens, shredding, dry.

11, Rhizoma Cibotii: this product is the dry rhizome of Dicksoniaceae plant Rhizoma Cibotii.Autumn, season in winter two excavate, removing silt, dry; Or remove hard root, petiole and golden yellow fine hair, and cut sheet, dry, be " raw Rhizoma Cibotii sheet "; After steaming, shine to six, seventy percent dry, cut sheet, dry, be " ripe Rhizoma Cibotii sheet ".

12, Fructus Psoraleae: this product is the dry mature fruit of legumes psoraleae.To gather during fruit maturation in autumn infructescence, dry, rub fruit, removing impurity.

13, Fructus Alpiniae Oxyphyllae: be the fruit of zingiberaceous plant Fructus Alpiniae Oxyphyllae.Harvesting when fruit is brown, White flesh minimizing between 5 ~ June, removing fruit stem, gets Fructus Alpiniae Oxyphyllae and puts in pot, fry to shell burned black, take out cold, and removing shell, gets core and smash use to pieces.

18, Radix Adenophorae (Radix Glehniae): autumn, plane was adopted, removing aerial parts and fibrous root, scrape off rough bark, immediately dry.

17, Radix Polygoni Multiflori: this product is the dried root of polygonum multiflorum thunb, and its rattan claims " Caulis Polygoni Multiflori ".Autumn, winter two excavate when season, leaf was withered, two ends of pruning, and clean, individual greatly be cut into block, dry.

14, Semen Astragali Complanati: this product is the dry mature seed of leguminous plant astragatus complanatus.Tap plant when time of the year when autumn changes into winter, fruit maturation not yet ftractureed, dry, lay seed, removing impurity, dries.

15, Exocarpium Benincasae: this product is the dry outside rind of cucurbitaceous plant Fructus Benincasae.During edible Fructus Benincasae, clean, cut and get outside rind, dry;

16, Actinolitum: be asbestos Ore.The whole year can adopt, and after digging out, removes earth and assorted stone.Put and forge red in smokeless stove fire, take out and put in yellow wine and quench it, dry, fine ground.

19, Herba Dendrobii: the whole year can gather, after dry user gathers, removing impurity, slightly scald or softened by baking, then stranding limit, limit is baked with boiled water, rubs with the hands clean to sheath, dry.After Herba Dendrobii cuts off part fibrous root, stir-fry limit, limit is twisted into spiral type or spring-like, dries, and practises and claims " earrings dendrobium ".

20, Semen Allii Tuberosi: this product is the dry mature seed of liliaceous plant Folium Allii tuberosi.To gather during fruit maturation in autumn infructescence, dry, rub seed, removing impurity.

21, Rhizoma Polygonati: spring, Qiu Erji excavate, removing impurity, cleans, and slightly profit, cuts sheet, dry.

22, Rhizoma Cibotii: this product is the dry mature fruit of plant of Solanaceae lycium barbarum.Summer, autumn two gather when season, fruit took on a red color, hot-air seasoning, removing carpopodium.Or dry in the air to rhicnosis, dry, removing carpopodium.

23, Fructus Mori: this product is the dry fruit ear of moraceae plants Mulberry.Gather when 4 ~ June, fruit reddened, dry,

24, Fructus Ligustri Lucidi: this product is the dry mature fruit of Oleaceae plants Fructus Ligustri Lucidi.Gather during fruit maturation in winter, removing branch and leaf, after slightly steaming or putting in boiling water and slightly scald, dry;

25, Semen Sesami Nigrum: this product is the dry mature seed of Pedaliaceae (Pedaliaceae) Sesamum plant sesame.Tap plant during fruit maturation in autumn, dry, lay seed, removing impurity, then dry.Used time smashs to pieces.

26, the penis and tester of an ursine seal: Carnivora fur seal section fur seal, is used as medicine with male genital.

27, Radix Rehmanniae Preparata: this product is the Preparation process product of Radix Rehmanniae.Get clean Radix Rehmanniae, steam extremely black profit according to steaming method, take out, shine to when about most probably doing, cut sheet, dry, to obtain final product.

28, Herba Cistanches: this product is the fleshy stem of the dry zone scale leaf of orobanchaceae plant cistanche.Excavate when Seedling is not unearthed or is just unearthed more than spring, removing inflorescence, cutting, dries;

29, Gecko: this product is the dry body of Gekkonidae animal Gecko.The whole year all can catch, removing internal organs, wipes clean, struts with bamboo chip, makes all flat straight, cold drying.

30, Radix Paeoniae Alba: this product is the dry root of ranunculaceae plant Radix Paeoniae.Summer, Qiu Erji excavate, and clean, and remove end to end and radicula, put in boiling water after boiling rear removing crust or peeling and boil, dry.

31, Bulbus Lilii: autumn excavates, cleans, strips scale leaf, puts in boiling water and slightly scalds, dry.

32 Radix Ophiopogonis: this product is the dried root of liliaceous plant Radix Ophiopogonis.Summer excavates, and removing impurity, cleans, run through, draw down, dry.

33, Rhizoma Polygonati Odorati: this product is the dry rhizome of liliaceous plant Rhizoma Polygonati Odorati.Autumn excavates, and removing impurity, cleans, run through, cut sheet or section, dry.

1, by the Herba Cynomorii of described weight, Cornu Cervi Pantotrichum, Rhizoma Dioscoreae Septemlobae, Placenta Hominis, the Rhizoma Atractylodis Macrocephalae, Semen Phaseoli, Radix Angelicae Sinensis, Radix Morindae Officinalis, Medulla Junci, Herba Epimedii, Rhizoma Cibotii, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Astragali Complanati, Exocarpium Benincasae, Actinolitum, Radix Polygoni Multiflori, Radix Adenophorae (Radix Glehniae), Herba Dendrobii, Semen Allii Tuberosi, Rhizoma Polygonati, Fructus Lycii, Fructus Mori, Fructus Ligustri Lucidi, Semen Sesami Nigrum, the penis and tester of an ursine seal, Radix Rehmanniae Preparata, Herba Cistanches, Gecko, Radix Paeoniae Alba, Bulbus Lilii, Radix Ophiopogonis, Rhizoma Polygonati Odorati (Actinolitum, Gecko is decocted first) decoct with water twice, add water 8 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor,

2, add water the medicinal residues after first time filtration 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor;

3, merge twice decoction liquor, intense fire boils, then within 10 minutes, namely obtains medicinal liquid with slow fire boiling, is divided into four doses to take.

Medicine of the present invention has the function of nourishing essence and tonifying YANG, dredging microcirculation, conditioning blood vessels, is used for the treatment of male infertility instant effect, good effect, does not recur.

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.

The animal toxicity test of [test example 1] medicine of the present invention

Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 9 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's totally 36 examples for medical treatment.

2, diagnostic criteria

Causing the reason of male sterility varied, is that the complex clinical combined by many kinds of clinical diseases shows.Take dysspermatism as first cause, its concrete reason also can be divided into without sperm or sperm quantity very few, sperm quality is poor; Next is sexual dysfunction, such as impotence and premature ejaculation.Chronic disease, psychological factor, environmental factors also can cause sterile.

3, Therapeutic Method

Select above-mentioned medicament, take to patient, every twice-daily, each potion, take 7 days continuously.

4, efficacy assessment standard

Effective: male infertility symptom is fully recovered, recover normal.

Take a turn for the better: male infertility symptom alleviates, and progressively takes a turn for the better.

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form):

In above-mentioned treatment, by Drug therapy male infertility patient 36 example of the present invention, effective 33 examples of result, obvious effective rate is 91.67%, and take a turn for the better 2 examples, and improvement rate is 5.55%, and invalid 1 example, total effective rate is 97.22%.

Claims (3)

1. treat a medicine for male infertility, it is characterized in that: it is made up of the crude drug in following weight range:

2. medicine according to claim 1, wherein the consumption of each crude drug is:

3. the medicine according to right 1 or 2, is characterized in that: it comprises the following steps:

One, get the raw materials ready:

1, Herba Cynomorii: this product is the dry meat stem of Cynomoriaceae plant Herba Cynomorii,

Spring excavates, and removing inflorescence, cleans, run through, shave, dry,

2, Cornu Cervi Pantotrichum: Cornu Cervi Pantotrichum got by summer, Qiu Erji saw, after processing, dries,

Get Cornu Cervi Pantotrichum, burn remove floss, scraping, with the fine and soft body of Fabric tape winding, from saw kerf face, aperture pours into hot Chinese liquor, and constantly freshens the drink, and slightly steams, transection sheet to running through or fill with wine, flattens, dry,

3, Rhizoma Dioscoreae Septemlobae: spring, Qiu Junke excavate,

Dig out afterwash removing fibrous root, section is dried,

4, the penis and tester of an ursine seal: this product is the dry Placenta Hominis of Healthy People,

Fresh human placenta being removed amniotic membrane and umbilical cord, repeatedly rinsing to removing blood, steam or put in boiling water and steam thoroughly, dry, except dedust bits, pound into fritter or be ground into fine powder,

5, the Rhizoma Atractylodis Macrocephalae: excavate when withered and yellow, the upper leaf of inferior leads in winter becomes fragile, removing silt, dries or dries, then remove fibrous root,

6, Semen Phaseoli: autumn fruit maturation and do not ftracture time to choose Herb, dry, lay seed, removing impurity, then dry,

7, Radix Angelicae Sinensis: this product is the dry root of umbelliferae angelica,

Autumn end gathers, and removing impurity, cleans, run through, shave, dry or cold drying,

8, Radix Morindae Officinalis: this product is the dry root of Maguireothamnus speciosus Radix Morindae Officinalis,

The whole year all can excavate, and cleans, gets Radix Morindae Officinalis, steams thoroughly, remove core while hot, cutting according to steaming method, dry,

9, Medulla Junci: this product is the dry stem pith of rush family plant Medulla Junci,

Late summer extracts stem to autumn, dries, and takes out stem pith, removing impurity, the section of cutting,

10, Herba Epimedii: tap when summer, autumn, stem and leaf was luxuriant, the thick stalk of removing and impurity, removing impurity, wins blade, and spray clear water, slightly moistens, shredding, dry,

11, Rhizoma Cibotii: this product is the dry rhizome of Dicksoniaceae plant Rhizoma Cibotii,

Autumn, season in winter two excavate, removing silt, dry; Or remove hard root, petiole and golden yellow fine hair, and cut sheet, dry, be " raw Rhizoma Cibotii sheet "; After steaming, shine to six, seventy percent dry, cut sheet, dry, be " ripe Rhizoma Cibotii sheet ",

12, Fructus Psoraleae: this product is the dry mature fruit of legumes psoraleae,

To gather during fruit maturation in autumn infructescence, dry, rub fruit, removing impurity,

13, Fructus Alpiniae Oxyphyllae: be the fruit of zingiberaceous plant Fructus Alpiniae Oxyphyllae,

Harvesting when fruit is brown, White flesh minimizing between the 5--6 month, removing fruit stem, gets Fructus Alpiniae Oxyphyllae and puts in pot, fry to shell burned black, take out cold, and removing shell, gets core and smash use to pieces,

18, Radix Adenophorae (Radix Glehniae): autumn, plane was adopted, removing aerial parts and fibrous root, scrape off rough bark, immediately dry,

17, Radix Polygoni Multiflori: this product is the dried root of polygonum multiflorum thunb, and its rattan claims " Caulis Polygoni Multiflori ",

Autumn, winter two excavate when season, leaf was withered, two ends of pruning, and clean, individual greatly be cut into block, dry,

14, Semen Astragali Complanati: this product is the dry mature seed of leguminous plant astragatus complanatus,

Tap plant when time of the year when autumn changes into winter, fruit maturation not yet ftractureed, dry, lay seed, removing impurity, dries,

15, Exocarpium Benincasae: this product is the dry outside rind of cucurbitaceous plant Fructus Benincasae,

During edible Fructus Benincasae, clean, cut and get outside rind, dry;

16, Actinolitum: be asbestos Ore,

The whole year can adopt, and after digging out, removes earth and assorted stone,

Put and forge red in smokeless stove fire, take out and put in yellow wine and quench it, dry, fine ground,

19, Herba Dendrobii: the whole year can gather, after dry user gathers, removing impurity, slightly scald or softened by baking, then stranding limit, limit is baked with boiled water, rubs with the hands clean to sheath, dry,

After Herba Dendrobii cuts off part fibrous root, stir-fry limit, limit is twisted into spiral type or spring-like, dries, and practises and claims " earrings dendrobium ",

20, Semen Allii Tuberosi: this product is the dry mature seed of liliaceous plant Folium Allii tuberosi,

To gather during fruit maturation in autumn infructescence, dry, rub seed, removing impurity,

21, Rhizoma Polygonati: spring, Qiu Erji excavate, removing impurity, cleans, and slightly profit, cuts sheet, dry,

22, Rhizoma Cibotii: this product is the dry mature fruit of plant of Solanaceae lycium barbarum,

Summer, autumn two gather when season, fruit took on a red color, hot-air seasoning, removing carpopodium,

Or dry in the air to rhicnosis, dry, removing carpopodium,

23, Fructus Mori: this product is the dry fruit ear of moraceae plants Mulberry,

Gather when 4 ~ June, fruit reddened, dry,

24, Fructus Ligustri Lucidi: this product is the dry mature fruit of Oleaceae plants Fructus Ligustri Lucidi,

Gather during fruit maturation in winter, removing branch and leaf, after slightly steaming or putting in boiling water and slightly scald, dry;

25, Semen Sesami Nigrum: this product is the dry mature seed of Pedaliaceae (Pedaliaceae) Sesamum plant sesame,

Tap plant during fruit maturation in autumn, dry, lay seed, removing impurity, then dry, the used time smashs to pieces,

26, the penis and tester of an ursine seal: Carnivora fur seal section fur seal, is used as medicine with male genital,

27, Radix Rehmanniae Preparata: this product is the Preparation process product of Radix Rehmanniae,

Get clean Radix Rehmanniae, steam extremely black profit according to steaming method, take out, shine to when about most probably doing, cut sheet, dry, to obtain final product,

28, Herba Cistanches: this product is the fleshy stem of the dry zone scale leaf of orobanchaceae plant cistanche,

Excavate when Seedling is not unearthed or is just unearthed more than spring, removing inflorescence, cutting, dries;

29, Gecko: this product is the dry body of Gekkonidae animal Gecko,

The whole year all can catch, removing internal organs, wipes clean, struts with bamboo chip, makes all flat straight, cold drying,

30, Radix Paeoniae Alba: this product is the dry root of ranunculaceae plant Radix Paeoniae,

Summer, Qiu Erji excavate, and clean, and remove end to end and radicula, put in boiling water after boiling rear removing crust or peeling and boil, dry,

31, Bulbus Lilii: autumn excavates, cleans, strips scale leaf, puts in boiling water and slightly scalds, dry,

32 Radix Ophiopogonis: this product is the dried root of liliaceous plant Radix Ophiopogonis,

Summer excavates, and removing impurity, cleans, run through, draw down, dry,

33, Rhizoma Polygonati Odorati: this product is the dry rhizome of liliaceous plant Rhizoma Polygonati Odorati,

Autumn excavates, and removing impurity, cleans, run through, cut sheet or section, dry,

Two, prepare

1, by the Herba Cynomorii of described weight, Cornu Cervi Pantotrichum, Rhizoma Dioscoreae Septemlobae, Placenta Hominis, the Rhizoma Atractylodis Macrocephalae, Semen Phaseoli, Radix Angelicae Sinensis, Radix Morindae Officinalis, Medulla Junci, Herba Epimedii, Rhizoma Cibotii, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Astragali Complanati, Exocarpium Benincasae, Actinolitum, Radix Polygoni Multiflori, Radix Adenophorae (Radix Glehniae), Herba Dendrobii, Semen Allii Tuberosi, Rhizoma Polygonati, Fructus Lycii, Fructus Mori, Fructus Ligustri Lucidi, Semen Sesami Nigrum, the penis and tester of an ursine seal, Radix Rehmanniae Preparata, Herba Cistanches, Gecko, Radix Paeoniae Alba, Bulbus Lilii, Radix Ophiopogonis, Rhizoma Polygonati Odorati (Actinolitum, Gecko is decocted first) decoct with water twice, add water 8 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor,

2, add water the medicinal residues after first time filtration 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor;

3, merge twice decoction liquor, intense fire boils, then within 10 minutes, namely obtains medicinal liquid with slow fire boiling, is divided into four doses to take.