CN105412530A - Traditional Chinese medicine extract with bacteriostasis, scrap removing and itch relieving function and preparation method and application thereof - Google Patents

Traditional Chinese medicine extract with bacteriostasis, scrap removing and itch relieving function and preparation method and application thereof Download PDF

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Publication number
CN105412530A
CN105412530A CN201510980161.6A CN201510980161A CN105412530A CN 105412530 A CN105412530 A CN 105412530A CN 201510980161 A CN201510980161 A CN 201510980161A CN 105412530 A CN105412530 A CN 105412530A
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chinese medicine
medicine extract
hair
dandruff
parts
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CN105412530B (en
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傅国华
王兴林
刘少勇
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Guangzhou Guerlain Cosmetics Co Ltd
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Guangzhou Guerlain Cosmetics Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/52Juglandaceae (Walnut family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965Asparagus, e.g. garden asparagus or asparagus fern
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/55Liquid-liquid separation; Phase separation

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  • Health & Medical Sciences (AREA)
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Abstract

The invention discloses a traditional Chinese medicine extract with the bacteriostasis, scrap removing and itch relieving function and a preparation method and application thereof. The traditional Chinese medicine extract is prepared from, by weight, 40-60 parts of walnuts, 150-250 parts of almond, 150-250 parts of Chinese wax gourd seeds and 30-60 parts of radix asparagi. The raw materials are extracted through water, extracted liquid precipitates through ethanol or an ethanol solution, filtration is performed, and obtained filter liquor is the traditional Chinese medicine extract with the bacteriostasis, scrap removing and itch relieving function. The traditional Chinese medicine extract can be used for cleaning hair deeply and has the nourishing, bacteriostasis, scrap removing and itch relieving effect, and the cleaned hair is natural in gloss, soft, smooth and easy to tease. When the traditional Chinese medicine extract is used for a long time, the hair can be natural, healthy, supple, dull black and bright. The traditional Chinese medicine extract is mild in property, prepared from common nontoxic traditional Chinese medicine, and suitable for people with any hair quality and can be used for preparing liquid shampoo, cream shampoo, hair conditioners and other daily use chemicals.

Description

A kind of there is antibacterial anti-dandruff and itching-relieving efficacies Chinese medicine extract and preparation method and application
Technical field
The invention belongs to vegetable Chinese herbal medicine field and daily cosmetics technical field, particularly a kind of there is antibacterial anti-dandruff and itching-relieving efficacies Chinese medicine extract and preparation method and application.
Background technology
A lot of shampoo is by the transient clean hair dirt of synthetic or scalp top layer dandruff on the market at present, often fundamentally can not improve the microenvironment of hair quality or the generation of scalp dandruff.Chinese medicine compound hair washing is a kind of very traditional natural method, mainly based on the overall Dialectics thought of theory of Chinese medical science basis " lung associating with skin and hair ", " kidney governing bones store essential substances; its Hua Biao ", contrary treatment lung kidney is started with and is taken good care of scalp and root of hair portion, play righting to rectify a deviation the effect restored balance, improve overall and scalp microenvironment, thus improve the problems such as hair is withered, hair bifurcated, dandruff are many, scalp itch.For thoroughly solving scalp comprehensively, hair problem provide one solve path.
Summary of the invention
Primary and foremost purpose of the present invention is that the shortcoming overcoming prior art is with not enough, provides a kind of Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies.
Another object of the present invention is to provide the described preparation method with the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies.
The described application with the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies.
Object of the present invention is achieved through the following technical solutions: a kind of Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies, is prepared: Semen Juglandis 40 ~ 60 parts, 150 ~ 250 parts, Semen Armeniacae Amarum, Semen Benincasae 150 ~ 250 parts, Radix Asparagi 30 ~ 60 parts by following raw material according to the mass fraction.
The described Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies, is preferably prepared by following raw material according to the mass fraction: Semen Juglandis 40 ~ 60 parts, 150 ~ 200 parts, Semen Armeniacae Amarum, Semen Benincasae 150 ~ 200 parts, Radix Asparagi 30 ~ 60 parts; Be more preferably and prepared by following raw material according to the mass fraction: Semen Juglandis 40 ~ 50 parts, 150 ~ 200 parts, Semen Armeniacae Amarum, Semen Benincasae 150 ~ 200 parts, Radix Asparagi 40 ~ 50 parts; Most preferably be and prepared by following raw material according to the mass fraction: Semen Juglandis 50 parts, 200 parts, Semen Armeniacae Amarum, Semen Benincasae 200 parts, Radix Asparagi 50 parts.
The described preparation method with the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies, comprise following steps: with water, Semen Juglandis, Semen Armeniacae Amarum, Semen Benincasae and Radix Asparagi are extracted, then with ethanol or alcoholic solution, extracting solution is precipitated, filter, the filtrate obtained is the Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies.
Described extracting Semen Juglandis, Semen Armeniacae Amarum, Semen Benincasae and Radix Asparagi with water is extracted Semen Juglandis, Semen Armeniacae Amarum, Semen Benincasae and Radix Asparagi respectively or extract Semen Juglandis, Semen Armeniacae Amarum, Semen Benincasae and Radix Asparagi mixture with water.
The method of described extraction is preferably by water boiling and extraction or uses water supersound extraction.
The number of times of described use water boiling and extraction is preferably twice.
Described ethanol or the addition of alcoholic solution preferably by the final concentration joined after described extracting solution be percent by volume 60 ~ 65% calculate.
The described preparation method with the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies, preferably comprises following concrete steps:
(1) Semen Juglandis, Semen Armeniacae Amarum, Semen Benincasae and Radix Asparagi are mixed, obtain mixed material medicine;
(2) add the water being equivalent to mixed material medicine 5 ~ 12 times of quality, decoct 1 ~ 2 hour, filter, obtain filtrate;
(3) gained filtering residue is continued add 5 ~ 8 times of quality water, decoct 1 ~ 2 hour, obtain filtrate; Merge above-mentioned all filtrate, add ethanol or alcoholic solution, make concentration of alcohol in the mixed liquor finally obtained be percent by volume 60 ~ 65%, place, filter, decompression recycling ethanol, concentrated, obtain the Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies.
The consumption of the water described in step (2) is preferably equivalent to mixed material medicine quality 10 ~ 12 times.
The concentration of the alcoholic solution described in step (3) is preferably percent by volume 95%.
It is 1.1 ~ 1.2 as 60 DEG C of relative densities recorded that described concentrated degree is preferably concentrated.
Agents useful for same of the present invention and raw material are all commercially.
The described application of the Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies in hair-washing hair-care articles for use.
A kind of hair-washing hair-care articles for use, containing the above-mentioned Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies.
The concentration of the described Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies in described hair-washing hair-care articles for use is mass percent is 0.1 ~ 20%, and preferred mass percentage ratio is 1 ~ 10%.
The form of described hair-washing hair-care articles for use comprises shampoo, hair cream and hair conditioner.
The present invention has following advantage and beneficial effect relative to prior art:
(1) the Chinese medicine extract energy deep clean hair with antibacterial anti-dandruff and itching-relieving efficacies provided by the invention, plays nourishing, antibacterial, anti-dandruff, antipruritic effect, makes hair natural gloss soft, soft and smooth easy combing after washing.Life-time service can make hair natural health, submissive pitch-black beautiful.
(2) the Chinese medicine extraction properties gentleness with antibacterial anti-dandruff and itching-relieving efficacies provided by the invention, common nontoxic Chinese medicine, be applicable to any hair quality to use, can be used for preparing the cosmeticses of everyday use such as shampoo, hair cream, hair conditioner, the effect of excellent antibacterial, removing scurf and relieving itching can be reached, and preparation flow is simple, easy to operate, cost-effective.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but embodiments of the present invention are not limited thereto.
Embodiment 1
(1) Semen Juglandis 40 parts, 150 parts, Semen Armeniacae Amarum, Semen Benincasae 150 parts, Radix Asparagi 30 parts are carried out proportioning mixing, pulverize and sieve and obtain coarse powder.Above number is all mass fraction;
(2) claim above-mentioned raw materials 1Kg, add the water of 10kg, decoct 1.5 hours, filter, obtain filtrate;
(3) gained filtering residue is continued to add 8kg water, decoct 1 hour, filter, obtain filtrate;
(4) filtrate that obtains of combining step (2) and (3), be cooled to about 40 DEG C, ethanol is added under stirring, concentration of alcohol in the mixed liquor finally obtained is made to be percent by volume 65%, place, filter, after decompression recycling ethanol, being concentrated into relative density is 1.1 (60 DEG C record), must have the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies.
Embodiment 2
(1) Semen Juglandis 60 parts, 180 parts, Semen Armeniacae Amarum, Semen Benincasae 180 parts, Radix Asparagi 40 parts are carried out proportioning mixing, pulverize and sieve and obtain coarse powder.Above number is all mass fraction;
(2) claim above-mentioned raw materials 1Kg, add the water of 12kg, decoct 2 hours, filter, obtain filtrate;
(3) gained filtering residue is continued to add 5kg water, decoct 1 hour, filter, obtain filtrate;
(4) filtrate that obtains of combining step (2) and (3), be cooled to about 40 DEG C, ethanol is added under stirring, concentration of alcohol in the mixed liquor finally obtained is made to be percent by volume 65%, place, filter, after decompression recycling ethanol, being concentrated into relative density is 1.15 (60 DEG C record), must have the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies.
Embodiment 3
(1) Semen Juglandis 50 parts, 200 parts, Semen Armeniacae Amarum, Semen Benincasae 200 parts, Radix Asparagi 50 parts are carried out proportioning mixing, pulverize and sieve and obtain coarse powder.Above number is all mass fraction;
(2) claim above-mentioned raw materials 1Kg, add the water of 10kg, decoct 1.5 hours, filter, obtain filtrate;
(3) gained filtering residue is continued to add 8kg water, decoct 1 hour, filter, obtain filtrate;
(4) filtrate that obtains of combining step (2) and (3), be cooled to about 40 DEG C, ethanol is added under stirring, concentration of alcohol in the mixed liquor finally obtained is made to be percent by volume 60%, place, filter, after decompression recycling ethanol, being concentrated into relative density is 1.15 (60 DEG C record), must have the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies.
Embodiment 4
(1) Semen Juglandis 60 parts, 150 parts, Semen Armeniacae Amarum, Semen Benincasae 150 parts, Radix Asparagi 60 parts are carried out proportioning mixing, pulverize and sieve and obtain coarse powder.Above number is all mass fraction;
(2) claim above-mentioned raw materials 1Kg, add the water of 12kg, decoct 1.5 hours, filter, obtain filtrate;
(3) gained filtering residue is continued to add 5kg water, decoct 1 hour, filter, obtain filtrate;
(4) filtrate that obtains of combining step (2) and (3), be cooled to about 40 DEG C, ethanol is added under stirring, concentration of alcohol in the mixed liquor finally obtained is made to be percent by volume 60%, place, filter, after decompression recycling ethanol, being concentrated into relative density is 1.1 (60 DEG C record), must have the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies.
Embodiment 5
(1) Semen Juglandis 40 parts, 150 parts, Semen Armeniacae Amarum, Semen Benincasae 200 parts, Radix Asparagi 60 parts are carried out proportioning mixing, pulverize and sieve and obtain coarse powder.Above number is all mass fraction;
(2) claim above-mentioned raw materials 1Kg, add the water of 10kg, decoct 1 hour, filter, obtain filtrate;
(3) gained filtering residue is continued to add 8kg water, decoct 1 hour, filter, obtain filtrate;
(4) filtrate that obtains of combining step (2) and (3), be cooled to about 40 DEG C, ethanol is added under stirring, concentration of alcohol in the mixed liquor finally obtained is made to be percent by volume 65%, place, filter, after decompression recycling ethanol, being concentrated into relative density is 1.1 (60 DEG C record), must have the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies.
Comparative example 1
(1) Semen Juglandis 40 parts, 150 parts, Semen Armeniacae Amarum, Semen Benincasae 150 parts are carried out proportioning mixing, pulverize and sieve and obtain coarse powder.Above number is all mass fraction;
(2) claim above-mentioned raw materials 1Kg, add the water of 10kg, decoct 2 hours, filter, obtain filtrate;
(3) gained filtering residue is continued to add 8kg water, decoct 1 hour, filter, obtain filtrate;
(4) filtrate that obtains of combining step (2) and (3), be cooled to about 40 DEG C, ethanol is added under stirring, concentration of alcohol in the mixed liquor finally obtained is made to be percent by volume 65%, place, filter, after decompression recycling ethanol, being concentrated into relative density is 1.15 (60 DEG C record), obtains Chinese medicine extract.
Fungistatic effect embodiment
1, test specimen
The Chinese medicine extract that embodiment 1 ~ 5 and comparative example 1 obtain detects, and is positive control sample with ketoconazole.
2, test index
Minimum inhibitory concentration (MIC)
Think that the generation of the dandruff is relevant in the excessive multiplication hypertrophy of scalp with pityrosporum furfur (chlosma) at present.Can measure and more in vitro to pityrosporum furfur with or without inhibitory action and action intensity to evaluate anti-dandruff effect.With reference to yeast micro-dilution method in the M27-A scheme that American National Clinical Laboratory Standard committee (NCCLS) is worked out, drug sensitivity testing in vitro is carried out to Malassezia furfur (M.furfurCBS1878, Dutch Culture Collection).
3, experimental result
As shown in table 1 to In vitro culture bacterial strain Inhibition test result:
Table 1
Sample ID Minimum inhibitory concentration (MIC)
Embodiment 1 19.5mg/ml
Embodiment 2 39mg/ml
Embodiment 3 19.5mg/ml
Embodiment 4 39mg/ml
Embodiment 5 19.5mg/ml
Comparative example 1 78mg/ml
Ketoconazole 0.03μg/ml
Note: the activity of Malassezia furfur (M.furfurCBS1878) bacterium liquid is about 5.0 × 10 5cfu/ml.
According to test data, the embodiment of the present invention 1 ~ 5 and comparative example 1 extract all have certain fungistatic effect, and the extract fungistatic effect that comparative example 1 obtains is lower than embodiment 1 ~ 5 extract.
Application Example
Shampoo formula is as shown in table 2, is added to respectively in shampoo by the Chinese medicine extract that above-described embodiment 1 ~ 5 and comparative example 1 obtain, called after shampoo 1, shampoo 2, shampoo 3, shampoo 4, shampoo 5, comparative example 1 respectively with mass ratio 8%; Blank group replaces Chinese medicine extract to be made into by table 2 with deionized water.
Table 2
Material composition Mass percent (%)
Sodium laureth sulfate 5
Dodecyldimethylammonium hydroxide inner salt 4
Dimethiconol 1
Coconut oleoyl amine DEA 2
Polyquaternary ammonium salt-7 0.5
Deionized water 77.97
Chinese medicine extract 8
Castor oil-base maleic acid esters 0.5
Methylisothiazolinone 0.01
Citric acid 0.02
Sodium chloride 1
Human efficiency's effect example
1, relieving itching and removing dandruff effect assessment
(1) evaluation methodology of relieving itching and removing dandruff
The experiment number of often kind of shampoo is 24 people, and man 12 example, female 12 example, at 20 ~ 60 years old age, all has head pruritus, the symptom that dandruff is many.
Using method: wash weekly twice shampoo of the present invention, according to the dense degree of hair, each 20 ~ 100ml, carries out 2 months.
Result of the test:
Criterion of therapeutical effect is divided into: (1) is effective: head pruritus, and dandruff is many or have the fuel-displaced symptom of scalp concurrently and obtain suitable improvement; (2) effective: head pruritus, the symptom that dandruff is many or scalp is fuel-displaced reduces a little; (3) invalid: unchanged before and after using.
(2) effect assessment of relieving itching and removing dandruff is as shown in table 3:
Table 3
Sample Effective Effectively Invalid Total effective rate
Shampoo 1 17 6 1 95.83%
Shampoo 2 15 7 2 91.67%
Shampoo 3 18 6 0 100.00%
Shampoo 4 14 8 2 91.67%
Shampoo 5 16 5 3 87.50%
Reference examples 1 14 2 8 66.67%
Blank group 4 4 16 33.33%
From experiment effect, embodiment effect > reference examples 1 effect > blank example effect.Therefore the extracted form natural plant for preparing of embodiment 1 ~ 5 can effectively relieving itching and removing dandruff, particularly embodiment 3.
2, hair quality effect assessment is improved
(1) evaluation methodology of hair quality is improved
The experiment number of often kind of shampoo is 28 women, 20 ~ 60 years old age, and hair shows as withered damage in various degree, fragile easily broken, difficult combing.
Using method: wash weekly twice shampoo of the present invention, according to the dense degree of hair, each 20 ~ 100ml, carries out 2 months.
(2) result of the test:
Criterion of therapeutical effect is divided into: (1) is effective: cardability, the tensile force intensity of hair are significantly improved; (2) effective: cardability, the tensile force intensity of hair are improved a little; (3) invalid: unchanged before and after using.
The effect assessment improving hair quality is as shown in table 4:
Table 4
Sample Effective Effectively Invalid Total effective rate
Shampoo 1 17 8 3 89.29%
Shampoo 2 15 11 2 92.86%
Shampoo 3 18 9 1 96.43%
Shampoo 4 14 12 2 92.86%
Shampoo 5 16 9 3 89.29%
Reference examples 1 14 5 9 67.86%
Blank group 3 8 17 39.29%
From experiment effect, embodiment effect > reference examples 1 effect > blank example effect.Therefore the natural plant extracts that embodiment 1 ~ 5 prepares effectively can improve hair quality, particularly embodiment 3.
Above-described embodiment is the present invention's preferably embodiment; but embodiments of the present invention are not restricted to the described embodiments; change, the modification done under other any does not deviate from spirit of the present invention and principle, substitute, combine, simplify; all should be the substitute mode of equivalence, be included within protection scope of the present invention.

Claims (10)

1. there is a Chinese medicine extract for antibacterial anti-dandruff and itching-relieving efficacies, it is characterized in that being prepared by following raw material according to the mass fraction: Semen Juglandis 40 ~ 60 parts, 150 ~ 250 parts, Semen Armeniacae Amarum, Semen Benincasae 150 ~ 250 parts, Radix Asparagi 30 ~ 60 parts.
2. there is the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies according to claim 1, it is characterized in that being prepared by following raw material according to the mass fraction: Semen Juglandis 40 ~ 50 parts, 150 ~ 200 parts, Semen Armeniacae Amarum, Semen Benincasae 150 ~ 200 parts, Radix Asparagi 40 ~ 50 parts.
3. there is described in claim 1 or 2 preparation method of the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies, it is characterized in that comprising following steps: extract Semen Juglandis, Semen Armeniacae Amarum, Semen Benincasae and Radix Asparagi with water, then with ethanol or alcoholic solution, extracting solution is precipitated, filter, the filtrate obtained is the Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies.
4. there is the preparation method of the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies according to claim 3, it is characterized in that: the method for described extraction is for using water boiling and extraction or using water supersound extraction.
5. there is the preparation method of the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies according to claim 3, it is characterized in that: it is that percent by volume 60 ~ 65% calculates that described ethanol or the addition of alcoholic solution join the final concentration after described extracting solution by ethanol.
6. there is the preparation method of the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies according to any one of claim 3 ~ 5, it is characterized in that comprising following concrete steps:
(1) Semen Juglandis, Semen Armeniacae Amarum, Semen Benincasae and Radix Asparagi are mixed, obtain mixed material medicine;
(2) add the water being equivalent to mixed material medicine 5 ~ 12 times of quality, decoct 1 ~ 2 hour, filter, obtain filtrate;
(3) gained filtering residue is continued add 5 ~ 8 times of quality water, decoct 1 ~ 2 hour, obtain filtrate; Merge above-mentioned all filtrate, add ethanol or alcoholic solution, make concentration of alcohol in the mixed liquor finally obtained be percent by volume 60% ~ 65%, place, filter, decompression recycling ethanol, concentrated, obtain the Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies.
7. there is the preparation method of the Chinese medicine extract of antibacterial anti-dandruff and itching-relieving efficacies according to claim 6, it is characterized in that:
The consumption of the water described in step (2) is for being equivalent to mixed material medicine quality 10 ~ 12 times;
Described concentrated degree is concentrated is 1.1 ~ 1.2 as 60 DEG C of relative densities recorded.
8. the application of the Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies in hair-washing hair-care articles for use described in claim 1 or 2.
9. hair-washing hair-care articles for use, is characterized in that: containing the Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies described in claim 1 or 2.
10. hair-washing hair-care articles for use according to claim 8, is characterized in that:
The concentration of the described Chinese medicine extract with antibacterial anti-dandruff and itching-relieving efficacies in described hair-washing hair-care articles for use is mass percent is 0.1 ~ 20%;
The form of described hair-washing hair-care articles for use is shampoo, hair cream or hair conditioner.
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CN107049904A (en) * 2017-05-16 2017-08-18 广州市柏亚化妆品有限公司 It is a kind of to be used for maintenance damaged hair and cause the submissive glossy shampoo of hair
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CN113679650A (en) * 2021-09-18 2021-11-23 韶关市曲江美达多食品加工有限公司 Asparagus cochinchinensis shampoo with effects of hairdressing and hair care
CN114869815A (en) * 2022-04-29 2022-08-09 福建片仔癀化妆品有限公司 Anti-dandruff bacteriostatic shampoo and preparation method thereof
CN114869815B (en) * 2022-04-29 2024-05-24 福建片仔癀化妆品有限公司 Anti-dandruff antibacterial shampoo and preparation method thereof

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