CN105412462A - 一种接骨颗粒及其制作方法 - Google Patents

一种接骨颗粒及其制作方法 Download PDF

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CN105412462A
CN105412462A CN201510966981.XA CN201510966981A CN105412462A CN 105412462 A CN105412462 A CN 105412462A CN 201510966981 A CN201510966981 A CN 201510966981A CN 105412462 A CN105412462 A CN 105412462A
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葛兴龙
缪美芬
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Dongyang Peoples Hospital
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Abstract

本发明公开了一种接骨颗粒及其制作方法，属于中药复方制剂技术领域。所述的接骨颗粒包括以下组分：当归10份；秦艽10份；泽兰10份；乳香10份；没药10份；桃仁10份；红花10份；苏木10份；骨碎补10份；赤芍15份；接骨木12份；补骨脂10份；自然铜10份；香附10份；延胡15份；儿茶10份；地鳖虫10份；川牛膝10份；牡丹皮10份；巴戟10份；菟丝子15份；川芎10份；甘草6份。本发明获得的接骨颗粒老少皆宜，食用方便，无毒无害，无副作用，固本培元，开胃消食，保肝护肝，预防疾病，癌症预防，提高免疫力，适用于跌打损伤，骨碎骨折，能迅速消肿止痛，活血化瘀，康复时间短，骨愈合效果好。

Description

一种接骨颗粒及其制作方法
技术领域
本发明属于中药复方制剂技术领域，特别涉及一种接骨颗粒及其制作方法。
背景技术
随着人口的日益增加，交通工具的快速发展，人们在日常生活之中，很难避免意外事故的发生，所导致的骨质损伤，造成骨折，患者疼痛难忍，致残率较高，常遗留有各种不同程度的后遗症，使人们生活质量下降，饱受病患痛苦的折磨。
现有骨伤病的治疗方法一般采用人工接骨、手术接骨等方法。采用借助X光机或其它手段，将骨折部复位后，利用夹板、石膏绷带或手术钢板固定，服消炎药或治疗跌打损伤药，静养三个月左右，但实施正骨复位后，由于利用外敷用药的渗透作用，使其疗效慢，以及患者自身因素多方面的原因，易使骨折部位出现不同程度的重叠移位，致使部位肿胀疼痛，造成伸屈功能减弱或丧失，给患者带来极大痛苦。如果采用手术钢板固定，在骨折愈合后，还需进行二次手术，取出钢板和固定钢钉，给患者造成的痛苦就可想而知了，并且在骨骼上又留下人为造成的螺钉孔，造成骨折的骨头再次修复，同时这又有感染骨髓炎的可能。
目前治疗骨折的药物虽然很多，但还存在骨碎愈合不佳，消肿止痛速度慢，治疗时间较长，使用效果差等问题。
发明内容
本发明的目的在于克服上述现有技术中存在的缺点与不足，提供一种接骨颗粒。
本发明的另一目的在于提供上述接骨颗粒的制备方法。
本发明的目的通过下述技术方案实现：一种接骨颗粒，按重量份计，包括以下组分：
作为优选实施方式，按重量份，还包含增稠剂5份；所述的增稠剂优选为糊精。
作为优选实施方式，按重量份，还包含干燥剂5份；所述的干燥剂优选为甘露醇。
作为优选实施方式，按重量份，还包含白糖8份，改善口感。
上述的接骨颗粒的制备方法，步骤如下：
1)将当归10份；秦艽10份；泽兰10份；乳香10份；没药10份；桃仁10份；红花10份；苏木10份；骨碎补10份；赤芍15份；接骨木12份；补骨脂10份；自然铜10份；香附10份；延胡15份；儿茶10份；地鳖虫10份；川牛膝10份；牡丹皮10份；巴戟10份；菟丝子15份；川芎10份；甘草6份按重量份计，混合均匀，然后放入粉碎机中进行粉碎，当粉碎到20目时，停止粉碎；
2)取步骤1)中的粉碎颗粒，粉碎颗粒与水按重量比1：10混合均匀，放入反应釜中，加热温度为90～100摄氏度，时间为3小时；
3)过滤，分离药渣和溶液，取出溶液备用；
4)将溶液加热到70～80℃，搅拌真空脱水，浓缩至固体含量30～40％时，加入按重量份计增稠剂5份和白砂糖8份，进行搅拌溶解；
5)搅拌溶解后，加入重量份计干燥剂5份；进行喷雾干燥成颗粒，制备获得接骨颗粒。
步骤5)所述的增稠剂优选为糊精；
步骤6)所述的干燥剂优选为甘露醇。
秦艽，祛风湿，清湿热，止痹痛；泽兰，驱风镇痛，消肿止痛；乳香，活血行气止痛，消肿生肌；没药，散瘀定痛，消肿生肌；桃仁，活血祛瘀，润肠通便，止咳平喘；苏木，活血祛瘀，消肿定痛；骨碎补、补骨脂，补肝，长骨髓；接骨木，风湿痹痛，筋骨疼痛；自然铜，散瘀止痛，续筋接骨；香附，疏肝解郁，理气宽中，调经止痛；地鳖虫，跌打损伤，淤血肿痛，闭经，产后瘀血腹痛；川牛膝，逐瘀通经，通利关节，利尿通淋；牡丹皮，凉血作用；巴戟，菟丝子，均具有长骨髓作用；川芎，为引药，能让药效发挥迅速，且效果好；甘草，为中和作用，让各味药混在一起，发挥更好的作用。
本发明相对于现有技术具有如下的优点及效果：
1.本发明中川芎，为引药，能让药效发挥迅速，且效果好，甘草，为中和作用，让各味药混在一起，发挥更好的作用。
2.本发明配方中的乳香等多味药材的加入，活血止痛，消肿生肌，与另外中药相辅相成，达到治疗效果。
3.本发明获得的接骨颗粒经实验证明，不但有接骨生精的作用，还具有保肝护肝、健胃消食的功效。
4.本发明在制备方法方面，各中药成分混合均匀，使用效果好，方便服用。
5.本发明的配方和方法，经药理实验证明，能够适用于高血脂和高血糖人群，适用范围广泛。
6、本发明中的各中药组分相辅相成，从人体各个系统入手，达到调理效果，从而使各味药发挥出“1+1”大于2的效果，同时具有保健效果。
本发明获得的接骨颗粒老少皆宜，食用方便，无毒无害，无副作用，固本培元，开胃消食，保肝护肝，预防疾病，祛风除痹，提高免疫力，适用于跌打损伤，骨碎骨折，能迅速消肿止痛，活血化瘀，康复时间短，骨愈合效果好。
具体实施方式
下面结合实施例对本发明作进一步详细的描述，但本发明的实施方式不限于此。
实施例1
本发明提供了一种接骨颗粒，按重量份计，包括以下组分：
本实施例中按重量份，还包含增稠剂5份；所述的增稠剂优选为糊精；按重量份，还包含干燥剂5份；所述的干燥剂优选为甘露醇；按重量份，还包含白糖8份。
上述的接骨颗粒的制备方法，步骤如下：
1)将当归10份；秦艽10份；泽兰10份；乳香10份；没药10份；桃仁10份；红花10份；苏木10份；骨碎补10份；赤芍15份；接骨木12份；补骨脂10份；自然铜10份；香附10份；延胡15份；儿茶10份；地鳖虫10份；川牛膝10份；牡丹皮10份；巴戟10份；菟丝子15份；川芎10份；甘草6份按重量份计，混合均匀，然后放入粉碎机中进行粉碎，当粉碎到20目时，停止粉碎；
2)取步骤1)中的粉碎颗粒，粉碎颗粒与水按重量比1：10混合均匀，放入反应釜中，加热温度为90摄氏度，时间为3小时；；
3)过滤，分离药渣和溶液，取出溶液备用；
4)将溶液加热到70℃，搅拌真空脱水，浓缩至固体含量30％时，加入按重量份计增稠剂5份和白砂糖8份，进行搅拌溶解；
5)搅拌溶解后，加入重量份计干燥剂5份；进行喷雾干燥成颗粒，制备获得接骨颗粒。
步骤5)所述的增稠剂优选为糊精；
步骤6)所述的干燥剂优选为甘露醇。。
实施例2
本实施例与实施例1不同之处在于：本实施例中的步骤2)中的加热温度为100摄氏度，步骤4)中的加热温度为80摄氏度，固体含量为40％。
实施例1～2制备获得的接骨颗粒中所包含的秦艽，祛风湿，清湿热，止痹痛；泽兰，驱风镇痛，消肿止痛；乳香，活血行气止痛，消肿生肌；没药，散瘀定痛，消肿生肌；桃仁，活血祛瘀，润肠通便，止咳平喘；苏木，活血祛瘀，消肿定痛；骨碎补、补骨脂，补肝，长骨髓；接骨木，风湿痹痛，筋骨疼痛；自然铜，散瘀止痛，续筋接骨；香附，疏肝解郁，理气宽中，调经止痛；地鳖虫，跌打损伤，淤血肿痛，闭经，产后瘀血腹痛；川牛膝，逐瘀通经，通利关节，利尿通淋；牡丹皮，凉血作用；巴戟，菟丝子，均具有长骨髓作用；川芎，为引药，能让药效发挥迅速，且效果好；甘草，为中和作用，让各味药混在一起，发挥更好的作用。
本发明获得的接骨颗粒，老少皆宜，食用方便，无毒无害，无副作用，固本培元，开胃消食，保肝护肝，预防疾病，癌症预防，提高免疫力，适用于跌打损伤，骨碎骨折，能迅速消肿止痛，活血化瘀，康复时间短，骨愈合效果好。
上述实施例为本发明较佳的实施方式，但本发明的实施方式并不受上述实施例的限制，其他的任何未背离本发明的精神实质与原理下所作的改变、修饰、替代、组合、简化，均应为等效的置换方式，都包含在本发明的保护范围之内。

Claims (6)

1.一种接骨颗粒，其特征在于，按重量份计，包括以下组分：
2.根据权利要求1所述的接骨颗粒，其特征在于：按重量份，还包含增稠剂5份；所述的增稠剂优选为糊精。
3.根据权利要求1所述的接骨颗粒，其特征在于：按重量份，还包含干燥剂5份；所述的干燥剂优选为甘露醇。
4.根据权利要求1所述的接骨颗粒，其特征在于：按重量份，还包含白糖8份。
5.根据权利要求1～4任一项所述的接骨颗粒的制备方法，其特征在于：步骤如下：
1)将当归10份；秦艽10份；泽兰10份；乳香10份；没药10份；桃仁10份；红花10份；苏木10份；骨碎补10份；赤芍15份；接骨木12份；补骨脂10份；自然铜10份；香附10份；延胡15份；儿茶10份；地鳖虫10份；川牛膝10份；牡丹皮10份；巴戟10份；菟丝子15份；川芎10份；甘草6份按重量份计，混合均匀，然后放入粉碎机中进行粉碎，当粉碎到20目时，停止粉碎；
2)取步骤1)中的粉碎颗粒，粉碎颗粒与水按重量比1：10混合均匀，放入反应釜中，加热温度为90～100摄氏度，时间为3小时；；
3)过滤，分离药渣和溶液，取出溶液备用；
4)将溶液加热到70～80℃，搅拌真空脱水，浓缩至固体含量30～40％时，加入按重量份计增稠剂5份和白砂糖8份，进行搅拌溶解；
5)搅拌溶解后，加入重量份计干燥剂5份；进行喷雾干燥成颗粒，制备获得接骨颗粒。
6.根据权利要求5所述的接骨颗粒的制备方法，其特征在于：步骤4)所述的增稠剂为糊精；
步骤(5)所述的干燥剂为甘露醇。
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CN106177593A (zh) * 2016-08-31 2016-12-07 韦志春 一种跌打接骨散颗粒及其制备方法
CN114788848A (zh) * 2021-01-25 2022-07-26 江西省人民医院 一种适用于跌打消肿的中药

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CN104800443A (zh) * 2015-04-02 2015-07-29 赵志勇 一种补肾生髓续骨剂
CN105106528A (zh) * 2015-09-22 2015-12-02 孔盟 一种用于髌骨骨折术后恢复的中药制剂及其制备方法

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CN104800443A (zh) * 2015-04-02 2015-07-29 赵志勇 一种补肾生髓续骨剂
CN105106528A (zh) * 2015-09-22 2015-12-02 孔盟 一种用于髌骨骨折术后恢复的中药制剂及其制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177593A (zh) * 2016-08-31 2016-12-07 韦志春 一种跌打接骨散颗粒及其制备方法
CN114788848A (zh) * 2021-01-25 2022-07-26 江西省人民医院 一种适用于跌打消肿的中药

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