CN105412280A - 一种治疗肝胆结石的中药制剂 - Google Patents
一种治疗肝胆结石的中药制剂 Download PDFInfo
- Publication number
- CN105412280A CN105412280A CN201511012834.5A CN201511012834A CN105412280A CN 105412280 A CN105412280 A CN 105412280A CN 201511012834 A CN201511012834 A CN 201511012834A CN 105412280 A CN105412280 A CN 105412280A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- medicine preparation
- traditional chinese
- stones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title claims abstract description 25
- 239000004575 stone Substances 0.000 title claims abstract description 16
- 201000001883 cholelithiasis Diseases 0.000 title abstract description 7
- 208000001130 gallstones Diseases 0.000 title abstract description 4
- 230000002440 hepatic effect Effects 0.000 title abstract 2
- 210000004185 liver Anatomy 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 210000000941 bile Anatomy 0.000 claims description 11
- 230000000694 effects Effects 0.000 abstract description 6
- 210000000232 gallbladder Anatomy 0.000 abstract description 4
- 230000001225 therapeutic effect Effects 0.000 abstract description 3
- 208000002193 Pain Diseases 0.000 abstract description 2
- 230000003750 conditioning effect Effects 0.000 abstract description 2
- 238000007596 consolidation process Methods 0.000 abstract description 2
- 230000036407 pain Effects 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 238000012795 verification Methods 0.000 abstract description 2
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 abstract 1
- 235000003097 Artemisia absinthium Nutrition 0.000 abstract 1
- 240000001851 Artemisia dracunculus Species 0.000 abstract 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 235000009917 Crataegus X brevipes Nutrition 0.000 abstract 1
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 abstract 1
- 235000009685 Crataegus X maligna Nutrition 0.000 abstract 1
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 abstract 1
- 235000009486 Crataegus bullatus Nutrition 0.000 abstract 1
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 abstract 1
- 235000009682 Crataegus limnophila Nutrition 0.000 abstract 1
- 235000004423 Crataegus monogyna Nutrition 0.000 abstract 1
- 240000000171 Crataegus monogyna Species 0.000 abstract 1
- 235000002313 Crataegus paludosa Nutrition 0.000 abstract 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 241000195954 Lycopodium clavatum Species 0.000 abstract 1
- 239000001138 artemisia absinthium Substances 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 238000007599 discharging Methods 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- 238000011282 treatment Methods 0.000 description 22
- 208000024891 symptom Diseases 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000002980 postoperative effect Effects 0.000 description 4
- 238000003384 imaging method Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 206010061695 Biliary tract infection Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000003591 anti-choleraic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000013 bile duct Anatomy 0.000 description 1
- 210000003445 biliary tract Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 230000035568 catharsis Effects 0.000 description 1
- 208000003167 cholangitis Diseases 0.000 description 1
- 239000000731 choleretic agent Substances 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗肝胆结石的中药制剂,由以下重量份的中药制剂原料制成:伸筋草32-45份,艾叶30-39份,二母宁21-31份,猪牙皂12-28份,山楂叶13-27份,青风藤9-17份,大枣5-14份,茵陈3-7份,川楝子5-10份。本发明配方合理,服用方便安全,未发现毒副作用,临床验证疗效确切、显著。多年临床观察表明,本药具有养阴柔肝,滋阴降火,消炎利胆排石功能,治疗肝内胆管结石的有效率高达990%以上,同时本药还可以用于减少术后残石率,预防结石复发,针对术前调理及术后巩固,效果显著。而且本发明的中药制剂制备成本低,治愈后不复发,解除了广大患者的痛苦,产生了良好的经济效益和社会效益。
Description
技术领域
本发明涉及一种治疗肝胆结石的中药制剂。
背景技术
肝、胆结石属于中医“肋瘤”“腹痛”“胃痛”等病之范畴。病因病机多为肝气郁结、肝失调达,胆附于肝,胆失疏泄、气滞血瘀、湿热阻滞、蕴结石化、煎熬成结石,停滞胆道,肝胆气机不化,故而为患。胆石症是临床常见病,多发病,近年来胆石症患者更是逐年递增。目前临床常用的治疗肝胆结石的方案包括西医手术、碎石治疗以及中成药口服治疗等。手术治疗肝胆结石的一大弊端就是术后结石的残余及复发。碎石治疗只适用于胆囊小结石,治愈不彻底,易复发;胆管切除术对患者造成的痛苦大,并且费用高,不适合工薪阶层患者。目前市面上治疗肝胆结石的中成药又良莠不齐,溶石排石效果差,对于减少术后残石率,预防结石复发更是效果不佳。
发明内容
本发明所要解决的技术问题是:供一种对肝胆结石行之有效的、价格低,治疗效果好且不复发的的中药制剂。为解决上述技术问题,本发明采用的技术方案是:
本发明提供的一种治疗肝胆结石的中药制剂,由以下重量份的中药制剂原料制成:伸筋草32-45份,艾叶30-39份,二母宁21-31份,猪牙皂12-28份,山楂叶13-27份,青风藤9-17份,大枣5-14份,茵陈3-7份,川楝子5-10份。
优选的,本发明提供的中药制剂由以下重量份的中药制剂原料制成:伸筋草41份,艾叶36份,二母宁28份,猪牙皂25份,山楂叶24份,青风藤13份,大枣10份,茵陈6份,川楝子8份。
用法用量:将上述中药制剂用温水浸泡30分钟后,用武火煮沸后再用文火煮30分钟,取药液150毫升,再加水二煎,将两次药液混合后过滤,分两次服用。每天两次,饭后服用。
疗程:15天为一疗程,需服用2-5疗程。
临床试验选取100例门诊和住院患者进行临床试验,这些患者依据临床症状体征,辅以超声、腹平片、实验室检查确诊为肝胆结石。年龄最大70岁,最小者18岁,病程最长者15年,最短1周,
服用实施例1制得的药对上述患者进行临床试验,三个疗程后检查患者病状。判断标准为:治愈:症状、体征消失,实验室,影像学检查结石消失。有效:症状、体征减轻,实验室,影像学检查结石较前减少或变小。无效:症状、体征减轻不明显,影像学检查结石体积数量无变化。实验结果显示:治愈患者92例,有效患者7例,无效患者1例,总有效率92%,证明本发明对肝胆结石具有明显的治疗效果。本发明的有益效果:
本发明配方合理,服用方便安全,未发现毒副作用,临床验证疗效确切、显著。多年临床观察表明,本药具有养阴柔肝,滋阴降火,消炎利胆排石功能,治疗肝内胆管结石的有效率高达990%以上,同时本药还可以用于减少术后残石率,预防结石复发,针对术前调理及术后巩固,效果显著。而且本发明的中药制剂制备成本低,治愈后不复发,解除了广大患者的痛苦,产生了良好的经济效益和社会效益。
具体实施方式
实施例1
本实施例提供的一种治疗肝胆结石的中药制剂,由以下重量份的中药制剂原料制成:伸筋草41份,艾叶36份,二母宁28份,猪牙皂25份,山楂叶24份,青风藤13份,大枣10份,茵陈6份,川楝子8份。
典型病例:
1.赵某,男,60岁,查体B超显示有胆结石,食欲不振,服用本发明实施例1的药物治疗,1个疗程后症状好转,巩固治疗2个疗程后,饮食基本正常,又巩固1个疗程后病症消失,随诊2年未见异常,身体健康。
2、鲁某,女,41岁,查体B超显示有胆结石合并胆道感染,服用本发明实施例1的药物治疗,1个疗程后症状缓解,饮食增加,3个疗程右肩背酸沉疼消失,继服2个疗程巩固治疗后,复诊B超显示未见结石出现,随诊1年半未见复发,恢复健康。
Claims (2)
1.一种治疗肝胆结石的中药制剂,其特征在于,由以下重量份的中药制剂原料制成:伸筋草32-45份,艾叶30-39份,二母宁21-31份,猪牙皂12-28份,山楂叶13-27份,青风藤9-17份,大枣5-14份,茵陈3-7份,川楝子5-10份。
2.根据权利要求1所述的中药制剂,其特征在于,由以下重量份的中药制剂原料制成:伸筋草41份,艾叶36份,二母宁28份,猪牙皂25份,山楂叶24份,青风藤13份,大枣10份,茵陈6份,川楝子8份。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201511012834.5A CN105412280A (zh) | 2015-12-31 | 2015-12-31 | 一种治疗肝胆结石的中药制剂 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201511012834.5A CN105412280A (zh) | 2015-12-31 | 2015-12-31 | 一种治疗肝胆结石的中药制剂 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105412280A true CN105412280A (zh) | 2016-03-23 |
Family
ID=55491129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201511012834.5A Pending CN105412280A (zh) | 2015-12-31 | 2015-12-31 | 一种治疗肝胆结石的中药制剂 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105412280A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105853582A (zh) * | 2016-04-08 | 2016-08-17 | 广州暨南生物医药研究开发基地有限公司 | 一种含有艾叶的治疗胆石症的药物制剂及其制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104435739A (zh) * | 2014-12-24 | 2015-03-25 | 张冬 | 一种治疗肝胆结石的中药制剂及其制备方法 |
-
2015
- 2015-12-31 CN CN201511012834.5A patent/CN105412280A/zh active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104435739A (zh) * | 2014-12-24 | 2015-03-25 | 张冬 | 一种治疗肝胆结石的中药制剂及其制备方法 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105853582A (zh) * | 2016-04-08 | 2016-08-17 | 广州暨南生物医药研究开发基地有限公司 | 一种含有艾叶的治疗胆石症的药物制剂及其制备方法 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101274087B (zh) | 利胆排石中药汤剂 | |
CN104523865A (zh) | 一种治疗乳腺疾病的药物 | |
CN100444888C (zh) | 用于治疗乙肝和肝癌的中草药丸 | |
CN103142737B (zh) | 一种治疗骨折气滞血瘀症的中药胶囊及其制备方法 | |
CN105412280A (zh) | 一种治疗肝胆结石的中药制剂 | |
CN102205096B (zh) | 一种治疗附件炎、盆腔炎的药物 | |
CN104524458A (zh) | 一种治疗肝胆结石的中药散剂及其制备方法 | |
CN104435739A (zh) | 一种治疗肝胆结石的中药制剂及其制备方法 | |
CN105343222A (zh) | 一种治疗肝胆结石的中药制剂 | |
CN105362969A (zh) | 治疗肝胆结石的中药汤剂 | |
CN105435124A (zh) | 治疗肝胆结石的中药汤剂 | |
CN105456676A (zh) | 一种治疗肝胆结石的中药 | |
CN103041026B (zh) | 治疗肝胆结石的中药及其制备方法 | |
CN103041316B (zh) | 一种治疗肝胆结石的中药及其制备方法 | |
CN104127827A (zh) | 一种治疗胆道结石症的中药制剂 | |
CN103933177B (zh) | 一种治疗肠梗阻的药剂的制备方法 | |
CN102836346B (zh) | 一种治疗腰椎间盘突出的中药 | |
CN102949672A (zh) | 一种治疗盆腔炎的药物 | |
CN105998968A (zh) | 一种治疗湿热型外阴炎的药物组合物 | |
CN104491088A (zh) | 一种治疗肝胆结石的中药组合物及其制备方法 | |
CN105596694A (zh) | 一种治疗肝胆结石的中药 | |
CN105250641A (zh) | 治疗风湿病的中药组合物 | |
CN105079202A (zh) | 一种片仔癀痔疮软膏及其制备方法 | |
CN105169106A (zh) | 一种治疗乳腺增生的中药制剂 | |
CN104338088A (zh) | 治疗前列腺增生症的外用中药膏剂 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160323 |
|
WD01 | Invention patent application deemed withdrawn after publication |