CN105410940B - A kind of health food including xanthans - Google Patents
A kind of health food including xanthans Download PDFInfo
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- CN105410940B CN105410940B CN201510987470.6A CN201510987470A CN105410940B CN 105410940 B CN105410940 B CN 105410940B CN 201510987470 A CN201510987470 A CN 201510987470A CN 105410940 B CN105410940 B CN 105410940B
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- 229920001285 xanthan gum Polymers 0.000 title claims abstract description 33
- 235000013402 health food Nutrition 0.000 title claims abstract description 20
- 150000001875 compounds Chemical class 0.000 claims abstract description 43
- 239000000654 additive Substances 0.000 claims abstract description 17
- 230000000996 additive effect Effects 0.000 claims abstract description 16
- 229940126062 Compound A Drugs 0.000 claims abstract description 14
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 claims abstract description 14
- LVTJOONKWUXEFR-FZRMHRINSA-N protoneodioscin Natural products O(C[C@@H](CC[C@]1(O)[C@H](C)[C@@H]2[C@]3(C)[C@H]([C@H]4[C@@H]([C@]5(C)C(=CC4)C[C@@H](O[C@@H]4[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@H](CO)O4)CC5)CC3)C[C@@H]2O1)C)[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1 LVTJOONKWUXEFR-FZRMHRINSA-N 0.000 claims abstract description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
- 239000000706 filtrate Substances 0.000 claims description 16
- 239000000284 extract Substances 0.000 claims description 13
- 206010013786 Dry skin Diseases 0.000 claims description 12
- 238000001035 drying Methods 0.000 claims description 12
- 235000019441 ethanol Nutrition 0.000 claims description 12
- 239000012467 final product Substances 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 12
- 239000000463 material Substances 0.000 claims description 11
- 239000008267 milk Substances 0.000 claims description 9
- 235000013336 milk Nutrition 0.000 claims description 9
- 210000004080 milk Anatomy 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 9
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 8
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 8
- 241000180649 Panax notoginseng Species 0.000 claims description 8
- 239000006228 supernatant Substances 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 6
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 4
- 241001148782 Davallia Species 0.000 claims description 4
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 4
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 4
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 4
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 4
- 244000068988 Glycine max Species 0.000 claims description 4
- 235000010469 Glycine max Nutrition 0.000 claims description 4
- 244000241838 Lycium barbarum Species 0.000 claims description 4
- 235000015459 Lycium barbarum Nutrition 0.000 claims description 4
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 claims description 4
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims description 4
- 238000009835 boiling Methods 0.000 claims description 4
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 claims description 4
- 239000001527 calcium lactate Substances 0.000 claims description 4
- 235000011086 calcium lactate Nutrition 0.000 claims description 4
- 229960002401 calcium lactate Drugs 0.000 claims description 4
- 238000005119 centrifugation Methods 0.000 claims description 4
- 230000006837 decompression Effects 0.000 claims description 4
- 238000005538 encapsulation Methods 0.000 claims description 4
- 238000000265 homogenisation Methods 0.000 claims description 4
- 238000002390 rotary evaporation Methods 0.000 claims description 4
- 239000000661 sodium alginate Substances 0.000 claims description 4
- 235000010413 sodium alginate Nutrition 0.000 claims description 4
- 229940005550 sodium alginate Drugs 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 240000001949 Taraxacum officinale Species 0.000 claims 1
- 208000001132 Osteoporosis Diseases 0.000 abstract description 15
- 235000013305 food Nutrition 0.000 abstract description 10
- 239000003814 drug Substances 0.000 abstract description 9
- 229940079593 drug Drugs 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 6
- 238000012545 processing Methods 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 6
- 229960005069 calcium Drugs 0.000 description 6
- 239000011575 calcium Substances 0.000 description 6
- 229910052791 calcium Inorganic materials 0.000 description 6
- 210000000988 bone and bone Anatomy 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 230000037182 bone density Effects 0.000 description 4
- 239000013642 negative control Substances 0.000 description 4
- 206010039984 Senile osteoporosis Diseases 0.000 description 3
- 241000245665 Taraxacum Species 0.000 description 3
- 235000005911 diet Nutrition 0.000 description 3
- 108010048734 sclerotin Proteins 0.000 description 3
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 241000589649 Xanthomonas campestris pv. campestris Species 0.000 description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 2
- 235000013365 dairy product Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000005360 mashing Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 208000001685 postmenopausal osteoporosis Diseases 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- 208000008035 Back Pain Diseases 0.000 description 1
- 241001474374 Blennius Species 0.000 description 1
- 208000020084 Bone disease Diseases 0.000 description 1
- 206010005963 Bone formation increased Diseases 0.000 description 1
- 235000006008 Brassica napus var napus Nutrition 0.000 description 1
- 240000007124 Brassica oleracea Species 0.000 description 1
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 1
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 1
- 206010006966 Calcium intoxication Diseases 0.000 description 1
- 241001674939 Caulanthus Species 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 208000000913 Kidney Calculi Diseases 0.000 description 1
- 241000406668 Loxodonta cyclotis Species 0.000 description 1
- 206010029148 Nephrolithiasis Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 241000589634 Xanthomonas Species 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 238000010564 aerobic fermentation Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 210000003323 beak Anatomy 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 229940084954 dexamethasone 1 mg Drugs 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000013611 frozen food Nutrition 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000015243 ice cream Nutrition 0.000 description 1
- 201000000916 idiopathic juvenile osteoporosis Diseases 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 230000000366 juvenile effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000020124 milk-based beverage Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 235000021590 normal diet Nutrition 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 229930002330 retinoic acid Natural products 0.000 description 1
- 230000001835 salubrious effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
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- 230000002485 urinary effect Effects 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to food processing technology fields, disclose a kind of health food including xanthans, are prepared as follows and obtain：1）Prepare compound A；2）Prepare compound B；3）Prepare compound C；4）Prepare compound D；5）Prepare xanthans compound additive；6）Prepare health food.Food of the present invention can effectively prevent and treat osteoporosis, reduce the toxic side effect of drug.
Description
Technical field
The invention belongs to food processing technology fields, more particularly to a kind of health food including xanthans.
Background technology
Xanthans is also known as yellow glue, xanthan gum, and Xanthan Gum is that a kind of monospore generated by the fermentation of false xanthomonas is more
Sugar, through aerobic fermentation biotechnology, is cut by cabbage black rot xanthomonas campestris using carbohydrate as primary raw material
Disconnected 1,6- glycosidic bonds, after opening branch, in a kind of extracellular heteroglycan of acidity for being bonded to straight chain composition by Isosorbide-5-Nitrae-.Nineteen fifty-two by
The isolated Xanthomonas campestris pv. campestris of the United States Department of Agriculture Illinois Lilles Pi Ao the north research institute, and wild cabbage is made to carry
Object is taken to be converted into the water-soluble extracellular heteroglycan of acidity and obtain.
Xanthans is ideal thickener, suspending agent, emulsifier and forming agent in food industry, under certain harsh conditions
Performance ratio gelatin, the CMC of xanthans（Carboxymethyl cellulose）, the foodstuffs additive such as seaweed have more superiority.Applied to milk
Product（Such as cheese, fruit and milk drink, ice cream, Yoghourt）In can improve quality, increase stability, be easy to fragrance release, mouthfeel
The effects that fine and smooth salubrious.For fruit drink, there is good compatibility with other additives, it can Effective Suspension pulp and release
Flavor keeps liquid uniformly not stratified.It is added in beer, production bubble excellent.In frozen food, after multiple freeze-thaw,
Still there is good stability energy and water retention property, reduce frost crystalline substance, keep food mouthfeel smooth.
Osteoporosis is since bone density caused by many reasons and bone mass decline, and bone micro-structure destroys, and causes bone
Brittleness increases, to be easy to happen the systemic osteopathy of fracture.Osteoporosis is divided into primary and secondary two major class.It is primary
Property osteoporosis be divided into for Postmenopausal Osteoporosis (I types), senile osteoporosis (II type) and idiopathic sclerotin dredge
Three kinds of loose (including juvenile).Postmenopausal Osteoporosis typically occurs in after postmenopausal women in 5-10；Senile sclerotin
Osteoporosis refers generally to the osteoporosis that old man occurs after 70 years old；And idiopathic osteoporosis occurs mainly in teenager, the cause of disease is still
It is unknown；Wherein, occur most frequent to be senile osteoporosis.Osteoporosis is the important symbol of aging population society.
Conventional therapeutic modality is usually that drug therapy adds dietetic regulation at present, and common drug is anti-bone information drug and promotion
Bon e formation drug, diet mainly eat some and are rich in calcareous food.Prolonged administration of drugs is easy to cause kidney stone, higher urinary calcium
And calcium intoxication etc., white elephant can be also brought to liver kidney, while larger financial burden is also brought to patient.How only
It is prior art technical barrier urgently to be resolved hurrily that osteoporosis can be effectively treated through diet.
Invention content
In order to solve above-mentioned technical problem, the present invention provides a kind of health food including xanthans, the foods
Product can be effectively so that prevention and treatment osteoporosis, raising bone density and bone mass, can reduce medication or without medication, keep away
The toxic side effect that medicine band is come is exempted from.
To achieve the above object, the technical solution adopted by the present invention is as follows：
A kind of health food including xanthans, is prepared as follows and obtains：1）Prepare compound A；2）It prepares
Compound B；3）Prepare compound C；4）Prepare compound D；5）Prepare xanthans compound additive；6）Prepare health food.
Specifically, it is prepared as follows and obtains：
1）Prepare compound A：By Radix Salviae Miltiorrhizae, matrimony vine and Chinese yam according to 2:1：1 weight ratio is uniformly mixed, and adds 10 times of weight
Water decocts 1 hour, and filtrate is collected by filtration, and the pH that filtrate is adjusted with the hydrochloric acid solution of 1mol/L is 6.5, is then condensed into filtrate
Density is that the medicinal extract of 1.2g/ml is ground into powder after 80 DEG C of dryings to obtain the final product；
2）Prepare compound B：By the rhizome of davallia and Radix Notoginseng according to 1:1 weight ratio mixing, crushes, boiling is added to boil 20min, mistake
Filter collect filtrate, be then condensed into density be 1.2g/ml medicinal extract, after 80 DEG C of dryings, be ground into powder to get；The Radix Notoginseng
Mass ratio with water is 1:5；
3）Prepare compound C：By dandelion and malt according to 3:1 weight ratio mixing, then adding volume fraction is
It is impregnated 30 minutes in 70% ethyl alcohol, is subject to and does not cross, decompression rotary evaporation removes ethyl alcohol；It is 85% to add volume fraction again
Ethyl alcohol impregnates 30min, is subject to and does not cross, then supernatant is collected by centrifugation in 1000 turns/min, is at density by supernatant concentration
The medicinal extract of 1.2g/ml, after 80 DEG C of dryings, be ground into powder to get；
4）Prepare compound D：By oat and soybean according to 3:1 weight ratio is uniformly mixed, and is then ground to powdered, mistake
300 mesh sieve to obtain the final product；
5）Prepare xanthans compound additive：By xanthans, calcium lactate and sodium alginate according to 3:2:1 weight ratio is mixed
Close, stir evenly to get；
6）Prepare health food：By compound A, compound B, compound C, compound D and xanthans compound additive
It puts into milk, is uniformly mixed, is then preheating to 50 DEG C, carry out homogeneous and obtain mixed material, homogenization pressure is 18~
20Mpa；The mixed material after homogeneous is finally placed in 95 DEG C to sterilize 120 seconds, package encapsulation to obtain the final product；
The weight ratio of the compound A, compound B, compound C, compound D, xanthans compound additive and milk
For 5-9：7-10：9-15：12-21：1-2：500-1000.
The advantageous effect of health food of the present invention includes mainly as follows：The health-care food preparation technology of the present invention is unique, most
It extracts to limits and obtains active ingredient, reduce wastage of material, saved cost；Food of the present invention can give osteoporosis
People is edible, can effectively treat osteoporosis, improves bone density and bone mass；The present invention adds the xanthans in allowable range
Compound additive has thickening suspension effect, improves mouthfeel, supplemented with calcareous；The present invention selects a variety of medicinal herb components, rationally
Compatibility dexterously adds in dairy produce so that the edible function of dairy produce and the health therapy function of medicinal material are organically combined to one
It rises；The side effect that patient's Long-term taking medicine is brought is avoided, and alleviates the financial burden of patient；The system of health food of the present invention
Preparation Method simple possible, can be with large-scale industrial production.
Specific implementation mode
According to following embodiments, the present invention may be better understood.However, as it will be easily appreciated by one skilled in the art that real
It applies specific material proportion, process conditions and its result described in example and is merely to illustrate the present invention, without that should will not limit
The present invention described in detail in claims processed.
Embodiment 1
A kind of health food including xanthans, is prepared as follows and obtains：
1）Prepare compound A：By Radix Salviae Miltiorrhizae, matrimony vine and Chinese yam according to 2:1：1 weight ratio is uniformly mixed, and adds 10 times of weight
Water decocts 1 hour, and filtrate is collected by filtration, and the pH that filtrate is adjusted with the hydrochloric acid solution of 1mol/L is 6.5, is then condensed into filtrate
Density is that the medicinal extract of 1.2g/ml is ground into powder after 80 DEG C of dryings to obtain the final product；
2）Prepare compound B：By the rhizome of davallia and Radix Notoginseng according to 1:1 weight ratio mixing, crushes, boiling is added to boil 20min, mistake
Filter collect filtrate, be then condensed into density be 1.2g/ml medicinal extract, after 80 DEG C of dryings, be ground into powder to get；The Radix Notoginseng
Mass ratio with water is 1:5；
3）Prepare compound C：By dandelion and malt according to 3:1 weight ratio mixing, then adding volume fraction is
It is impregnated 30 minutes in 70% ethyl alcohol, is subject to and does not cross, decompression rotary evaporation removes ethyl alcohol；It is 85% to add volume fraction again
Ethyl alcohol impregnates 30min, is subject to and does not cross, then supernatant is collected by centrifugation in 1000 turns/min, is at density by supernatant concentration
The medicinal extract of 1.2g/ml, after 80 DEG C of dryings, be ground into powder to get；
4）Prepare compound D：By oat and soybean according to 3:1 weight ratio is uniformly mixed, and is then ground to powdered, mistake
300 mesh sieve to obtain the final product；
5）Prepare xanthans compound additive：By xanthans, calcium lactate and sodium alginate according to 3:2:1 weight ratio is mixed
Close, stir evenly to get；
6）Prepare health food：By compound A, compound B, compound C, compound D and xanthans compound additive
It puts into milk, is uniformly mixed, is then preheating to 50 DEG C, carry out homogeneous and obtain mixed material, homogenization pressure is 18~
20Mpa；The mixed material after homogeneous is finally placed in 95 DEG C to sterilize 120 seconds, package encapsulation to obtain the final product；
The weight ratio of the compound A, compound B, compound C, compound D, xanthans compound additive and milk
It is 5：7：9：12：1：500.
Edible way：Twice daily, each 200-300ml.
Embodiment 2
A kind of health food including xanthans, is prepared as follows and obtains：
1）Prepare compound A：By Radix Salviae Miltiorrhizae, matrimony vine and Chinese yam according to 2:1：1 weight ratio is uniformly mixed, and adds 10 times of weight
Water decocts 1 hour, and filtrate is collected by filtration, and the pH that filtrate is adjusted with the hydrochloric acid solution of 1mol/L is 6.5, is then condensed into filtrate
Density is that the medicinal extract of 1.2g/ml is ground into powder after 80 DEG C of dryings to obtain the final product；
2）Prepare compound B：By the rhizome of davallia and Radix Notoginseng according to 1:1 weight ratio mixing, then uses high-speed tissue mashing machine
Mashing adds boiling to boil 20min, filtrate is collected by filtration, and is then condensed into the medicinal extract that density is 1.2g/ml, after 80 DEG C of dryings, crushes
At powder to get；The mass ratio of the Radix Notoginseng and water is 1:5；
3）Prepare compound C：By dandelion and malt according to 3:1 weight ratio mixing, then adding volume fraction is
It is impregnated 30 minutes in 70% ethyl alcohol, is subject to and does not cross, decompression rotary evaporation removes ethyl alcohol；It is 85% to add volume fraction again
Ethyl alcohol impregnates 30min, is subject to and does not cross, then supernatant is collected by centrifugation in 1000 turns/min, is at density by supernatant concentration
The medicinal extract of 1.2g/ml, after 80 DEG C of dryings, be ground into powder to get；
4）Prepare compound D：By oat and soybean according to 3:1 weight ratio is uniformly mixed, and is then ground to powdered, mistake
300 mesh sieve to obtain the final product；
5）Prepare xanthans compound additive：By xanthans, calcium lactate and sodium alginate according to 3:2:1 weight ratio is mixed
Close, stir evenly to get；
6）Prepare health food：By compound A, compound B, compound C, compound D and xanthans compound additive
It puts into milk, is uniformly mixed, is then preheating to 50 DEG C, carry out homogeneous and obtain mixed material, homogenization pressure is 18~
20Mpa；The mixed material after homogeneous is finally placed in 95 DEG C to sterilize 120 seconds, package encapsulation to obtain the final product；
The weight ratio of the compound A, compound B, compound C, compound D, xanthans compound additive and milk
It is 9：10：15：21：2：1000.
Edible way：Twice daily, each 200-300ml.
Embodiment 3
Pharmacological evaluation
The influence of health food prepared by the edible present invention to SD rat blood serums calcium and writhing response；
SD rats, weight (250 ± 10) g is selected 30, to be provided by Shandong University's experimental animal center.It is randomly divided into 3
Group, blank control group 10, experimental group 10, negative control group.Blank control group gives physiological saline, experimental group of the present invention and
Negative control group gives dexamethasone 1mg/kg, and injection is primary every three days, intramuscular injection, meanwhile, combine vitamin A acid gavage, often
Its dosage 70mg/kg, totally three weeks.
Feeding methods：Blank control group and negative control group eat normal diet during modeling, and experimental group of the present invention is edible
The food of the embodiment of the present invention 1, daily 50ml.After 20 days, writhing number is detected, then tail portion takes blood, centrifuging and taking serum, with complete
Automatic biochemistry analyzer detects serum calcium levels.Referring to the following table 1
Table 1
| Classification | Serum calcium levels（mmol/L） | Writhing number in a quarter of an hour |
| Blank control group | 1.81±0.32 | Nothing |
| Experimental group of the present invention | 1.97±0.29 | 10±3 |
| Negative control group | 3.64±0.53 | 43±9 |
Conclusion：Experimental group serum calcium levels of the present invention are substantially reduced, it is seen that the calcium loss in sclerotin is less, and writhing time
Number greatly reduces, it is seen that has preferable analgesic activity.
Embodiment 4
Clinical typical case
Zhu, man, 56 years old；Pain in the back pain 20 years, recurrent exerbation, nearly half a year aggravate.Patient's long campaigns manual labor, long
It stands after sitting, when standing is unable to normal waking activity, and the breaking-out that is in a bad way every year is multiple.It is shown through X-ray：Lumbar curvature becomes
Directly, hyperosteogeny spur is in " beak shape ", narrowing of intervertebral space.It is diagnosed as：Senile osteoporosis.Adhere to eating daily to implement
Health food prepared by example 1, daily 500ml are eaten at twice, and after eating one month, symptom mitigates, and continue edible half a year, respectively
Kind symptom disappears, and bone density is close to normally.
It is above-mentioned that detailed description has been carried out to the present invention using specific embodiment, but not to the limit of the scope of the present invention
System, those skilled in the art should understand that, based on the technical solutions of the present invention, those skilled in the art need not pay
Go out various modifications or changes that creative work can be made still within protection scope of the present invention.
Claims (1)
1. a kind of health food including xanthans, which is characterized in that the health food is prepared as follows and obtains：
1）Prepare compound A：By Radix Salviae Miltiorrhizae, matrimony vine and Chinese yam according to 2:1:1 weight ratio is uniformly mixed, and adds the decocting of 10 times of weight
It boils 1 hour, filtrate is collected by filtration, the pH that filtrate is adjusted with the hydrochloric acid solution of 1mol/L is 6.5, and filtrate is then condensed into density
Powder is ground into for the medicinal extract of 1.2g/ml after 80 DEG C of dryings to obtain the final product；
2）Prepare compound B：By the rhizome of davallia and Radix Notoginseng according to 1:1 weight ratio mixing, crushes, and boiling is added to boil 20min, and filtering is received
Collect filtrate, be then condensed into density be 1.2g/ml medicinal extract, after 80 DEG C of dryings, be ground into powder to get；Wherein Radix Notoginseng and water
Mass ratio be 1:5；
3）Prepare compound C：By dandelion and malt according to 3:1 weight ratio mixing, it is 70% then to add volume fraction
It is impregnated 30 minutes in ethyl alcohol, decompression rotary evaporation removes ethyl alcohol；The ethyl alcohol that volume fraction is 85% is added again and impregnates 30min, so
Supernatant is collected by centrifugation in 1000 turns/min afterwards, by supernatant concentration at the medicinal extract that density is 1.2g/ml, after 80 DEG C of dryings, crushes
At powder to get；
4）Prepare compound D：By oat and soybean according to 3:1 weight ratio is uniformly mixed, and is then ground to powdered, mistake 300
Mesh sieves to obtain the final product；
5）Prepare xanthans compound additive：By xanthans, calcium lactate and sodium alginate according to 3:2:1 weight ratio mixing,
Stir evenly to get；
6）Prepare health food：Compound A, compound B, compound C, compound D and xanthans compound additive are put into
It into milk, is uniformly mixed, is then preheating to 50 DEG C, carry out homogeneous and obtain mixed material, homogenization pressure is 18~20Mpa；Most
The mixed material after homogeneous is placed in 95 DEG C afterwards to sterilize 120 seconds, package encapsulation to obtain the final product；The compound A, compound B, compound
C, the weight ratio of compound D, xanthans compound additive and milk are 5-9：7-10：9-15：12-21：1-2：500-1000.
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| CN109705374B (en) * | 2018-12-18 | 2022-04-26 | 山东阜丰发酵有限公司 | Preparation method of liquid xanthan gum |
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| CN104839727A (en) * | 2015-06-05 | 2015-08-19 | 南阳市汇博生物技术有限公司 | Medical emulsion food with total nutrient formula and preparation method thereof |
| CN105613737A (en) * | 2015-12-27 | 2016-06-01 | 山东阜丰发酵有限公司 | Xanthan-gum-added milk product and application thereof |
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| CN104839727A (en) * | 2015-06-05 | 2015-08-19 | 南阳市汇博生物技术有限公司 | Medical emulsion food with total nutrient formula and preparation method thereof |
| CN105613737A (en) * | 2015-12-27 | 2016-06-01 | 山东阜丰发酵有限公司 | Xanthan-gum-added milk product and application thereof |
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Denomination of invention: Health food containing xanthan gum Effective date of registration: 20211018 Granted publication date: 20180824 Pledgee: China Construction Bank Corporation Junan sub branch Pledgor: SHANDONG FUFENG FERMENTATION Co.,Ltd. Registration number: Y2021370000120 |
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Date of cancellation: 20230414 Granted publication date: 20180824 Pledgee: China Construction Bank Corporation Junan sub branch Pledgor: SHANDONG FUFENG FERMENTATION CO.,LTD. Registration number: Y2021370000120 |
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