CN1054069C - Preparation of external-use ointment for burn and scald - Google Patents
Preparation of external-use ointment for burn and scald Download PDFInfo
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- CN1054069C CN1054069C CN96111853A CN96111853A CN1054069C CN 1054069 C CN1054069 C CN 1054069C CN 96111853 A CN96111853 A CN 96111853A CN 96111853 A CN96111853 A CN 96111853A CN 1054069 C CN1054069 C CN 1054069C
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- ointment
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- 239000002674 ointment Substances 0.000 title claims abstract description 44
- 206010053615 Thermal burn Diseases 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 239000003814 drug Substances 0.000 claims abstract description 24
- 239000000843 powder Substances 0.000 claims abstract description 18
- 229940079593 drug Drugs 0.000 claims abstract description 11
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 8
- 241000218176 Corydalis Species 0.000 claims abstract description 8
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 8
- 229940105847 calamine Drugs 0.000 claims abstract description 8
- 229910052864 hemimorphite Inorganic materials 0.000 claims abstract description 8
- 239000011787 zinc oxide Substances 0.000 claims abstract description 8
- 235000014692 zinc oxide Nutrition 0.000 claims abstract description 8
- CPYIZQLXMGRKSW-UHFFFAOYSA-N zinc;iron(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[O-2].[Fe+3].[Fe+3].[Zn+2] CPYIZQLXMGRKSW-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000008157 edible vegetable oil Substances 0.000 claims abstract description 5
- 239000009286 sanguis draxonis Substances 0.000 claims description 12
- 239000006071 cream Substances 0.000 claims description 10
- 239000007766 cera flava Substances 0.000 claims description 7
- 239000002537 cosmetic Substances 0.000 claims description 7
- 210000003038 endothelium Anatomy 0.000 claims description 7
- 239000004575 stone Substances 0.000 claims description 7
- 239000000796 flavoring agent Substances 0.000 claims description 6
- 235000019634 flavors Nutrition 0.000 claims description 6
- 230000008030 elimination Effects 0.000 claims description 5
- 238000003379 elimination reaction Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 5
- 239000008158 vegetable oil Substances 0.000 claims description 5
- 230000001225 therapeutic effect Effects 0.000 abstract description 6
- 238000000034 method Methods 0.000 abstract description 5
- 239000007788 liquid Substances 0.000 abstract description 4
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 241000130781 Arnebia Species 0.000 abstract 1
- 241000099774 Cuscuta salina Species 0.000 abstract 1
- 241001644295 Fritillaria przewalskii Species 0.000 abstract 1
- 241000287828 Gallus gallus Species 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 239000011324 bead Substances 0.000 abstract 1
- 235000013871 bee wax Nutrition 0.000 abstract 1
- 239000012166 beeswax Substances 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 239000009136 dragon's blood Substances 0.000 abstract 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 description 30
- 208000027418 Wounds and injury Diseases 0.000 description 30
- 206010051814 Eschar Diseases 0.000 description 8
- 230000000694 effects Effects 0.000 description 8
- 231100000333 eschar Toxicity 0.000 description 8
- 206010030113 Oedema Diseases 0.000 description 5
- 239000003921 oil Substances 0.000 description 5
- 235000019198 oils Nutrition 0.000 description 5
- 206010039509 Scab Diseases 0.000 description 4
- 208000025865 Ulcer Diseases 0.000 description 4
- 230000035876 healing Effects 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- 229940099259 vaseline Drugs 0.000 description 4
- 238000004804 winding Methods 0.000 description 3
- 230000029663 wound healing Effects 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 230000008033 biological extinction Effects 0.000 description 2
- 239000010495 camellia oil Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 239000009416 jing wan hong Substances 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 239000011505 plaster Substances 0.000 description 2
- 206010040872 skin infection Diseases 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 208000009043 Chemical Burns Diseases 0.000 description 1
- 208000018380 Chemical injury Diseases 0.000 description 1
- 208000003656 Electric Burns Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 238000001266 bandaging Methods 0.000 description 1
- 125000001246 bromo group Chemical group Br* 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
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- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a preparation method of externally applied medicinal ointment for treating scalds and burns, which is characterized in that the externally applied medicinal ointment for treating scalds and burns is prepared from 15 kinds of medicines, such as Sichuan fritillary bulb, chicken gizzard-skin, golden thread (Sichuan), rhubarb, arnebia root, corydalis, cortex moutan, Chinese angelica root, dragon blood, beeswax, calcined red halloysite powder, calamine powder, calcined dragon bone powder, borneol powder, etc., as a prescription; the former 8 kinds of medicines are soaked in edible vegetable oil for a certain period of time, decocted in slow fire until medicine liquid drops into beads, and filtered to remove dregs; filter liquor is reboiled and stirred with the later 6 kinds of medicines to obtain ointment. Compared with the existing ointment, the ointment prepared by the method has good therapeutic effect. The cure rate of the ointment can be up to about 99% for 2 to 3 degrees of scalds and burns.
Description
The present invention relates to a kind of external Chinese medicine ointment that is used for the treatment of various wounds, burn, scald, skin infection ulcer, liquid permeability dermatitis, decubital ulcer etc.
Present external-applied ointments such as treatment wound, burn and scald burning hot cream commonly used, HUATUO GAO, JINGWANHONG cream, alleviated to a certain extent the wounded slight illness, quickened the healing of wound, improved skin graft survival rate.According to interrelated data, to 2-3 ° of burn and scald, the cure rate of burning hot cream and HUATUO GAO is about 68%, and the cure rate of JINGWANHONG cream is about 72%.This shows, generally have the patient about 30% to cure, stayed repent forever for many people with 2-3 ° of burn and scald of existing ointment treatment.
The objective of the invention is: a kind of preparation method that is used for the treatment of the external-applied ointment of burn and scald is provided, the ointment made from the method, existing ointment has better therapeutic, can reach about 99% the cure rate of 2-3 ° of burn and scald.
Technical scheme of the present invention comprises the steps:
A. be ready to following prescription according to proper proportion: Bulbus Fritillariae Cirrhosae, Endothelium Corneum Gigeriae Galli, Rhizoma Coptidis (river), Radix Et Rhizoma Rhei, Radix Arnebiae (Radix Lithospermi), Rhizoma Corydalis, Cortex Moutan, Radix Angelicae Sinensis, Sanguis Draxonis, Cera Flava, calcined akaishi cosmetics, calamine stone, Dragon bone(fried) powder, Borneolum Syntheticum powder; Be equipped with the proper amount of edible vegetable oil in addition; With preceding 8 flavor medicines drop into soak certain hour in the edible vegetable oils after, endure to medicine with warm fire and to drip into pearl, the elimination medicinal residues are endured and are boiled, and drop into the later Six-element medicine of Sanguis Draxonis again and stir into cream;
The percentage by weight of described prescription is: Bulbus Fritillariae Cirrhosae 6.2-10.2%, Endothelium Corneum Gigeriae Galli 3.1-5.1%, Rhizoma Coptidis (river) 10.6-16.6%, Radix Et Rhizoma Rhei 3.1-5.1%, Radix Arnebiae (Radix Lithospermi) 6.5-12.5%, Rhizoma Corydalis 6.5-12.5%, Cortex Moutan 4.1-8.1%, Radix Angelicae Sinensis 6.2-10.2%, Sanguis Draxonis 3.1-5.1%, Cera Flava 10.6-16.6%, calcined akaishi cosmetics 3.1-5.1%, calamine stone 3.1-5.1%, Dragon bone(fried) powder 6.2-10.2%, Borneolum Syntheticum powder 1.7-3.7%.
Show that through clinic trial the more conventional ointment of ointment that makes by the invention described above method can obviously reduce the time that stops 2-3 ° of empyrosis wound surface sepage and eliminate edema, accelerates wound healing, has the protection wound surface effect of similar allo-skin graft; Can be very fast molten soft, remove 3 ° of burn and scald eschars, be better than cutting the decrustation effect of crust operation; Ointment of the present invention can improve skin graft survival rate, 2-3 ° of burn and scald is cured reach about 99%; Slight burn and scald is had more the therapeutic effect that gets instant result; Wounds such as various wounds, skin infection ulcer, liquid permeability dermatitis, decubital ulcer also had extraordinary curative effect.
Be three specific embodiments of the present invention below.
Embodiment 1:
A, be ready to prescription as following weight percent: Bulbus Fritillariae Cirrhosae 6.4%, Endothelium Corneum Gigeriae Galli 5.1%, Rhizoma Coptidis (river) 10.8%, Radix Et Rhizoma Rhei 5.1%, Radix Arnebiae (Radix Lithospermi) 6.8%, Rhizoma Corydalis 12.5%, Cortex Moutan 4.4%, Radix Angelicae Sinensis 10.2%, Sanguis Draxonis 3.4%, Cera Flava 16.6%, calcined akaishi cosmetics 3.4%, calamine stone 5.1%, Dragon bone(fried) powder 6.5%, Borneolum Syntheticum powder 3.7%; Other is equipped with an amount of Oleum Camelliae;
B, will be preceding 8 flavor medicines drop in the edible camellia oils and soak 10 hours (summer), endure to medicine with warm fire and drip into pearl, the elimination medicinal residues are endured and are boiled, and drop into the later Six-element medicine of Sanguis Draxonis more successively and stir into cream.
Embodiment 2:
A, be ready to prescription as following weight percent: Bulbus Fritillariae Cirrhosae 10.2%, Endothelium Corneum Gigeriae Galli 3.1%, Rhizoma Coptidis (river) 14.5%, Radix Et Rhizoma Rhei 3.1%, Radix Arnebiae (Radix Lithospermi) 12.5%, Rhizoma Corydalis 6.5%, Cortex Moutan 8.1%, Radix Angelicae Sinensis 6.2%, Sanguis Draxonis 5.1%, Cera Flava 10.6%, calcined akaishi cosmetics 5.1%, calamine stone 3.1%, Dragon bone(fried) powder 10.2%, Borneolum Syntheticum powder 1.7%, be equipped with proper amount of edible Oleum Camelliae in addition;
B, will be preceding 8 flavor medicines drop in the edible flowers Oleum Brassicae campestriss and soak 14 hours (winter), endure to medicine with warm fire and drip into pearl, the elimination medicinal residues are endured and are boiled, and evenly drop into the later Six-element medicine of Sanguis Draxonis again and stir into cream.
Embodiment 3:
A, be ready to prescription as following weight percent: Bulbus Fritillariae Cirrhosae 8.2%, Endothelium Corneum Gigeriae Galli 4.1%, Rhizoma Coptidis (river) 13.6%, Radix Et Rhizoma Rhei 4.1%, Radix Arnebiae (Radix Lithospermi) 9.5%, Rhizoma Corydalis 9.4%, Cortex Moutan 6.1%, Radix Angelicae Sinensis 8.2%, Sanguis Draxonis 4.1%, Cera Flava 13.6%, calcined akaishi cosmetics 4.1%, calamine stone 4.1%, Dragon bone(fried) powder 8.2%, Borneolum Syntheticum powder 2.7%, be equipped with proper amount of edible Oleum Camelliae in addition;
B will be preceding 8 flavor medicines drop into and soak 12 hours (sky in spring and autumn) in the edible camellia oils, endure to medicine with warm fire and drip into pearl, the elimination medicinal residues are endured and are boiled, and evenly drop into the later Six-element medicine of Sanguis Draxonis again and stir into cream.
The addition of vegetable oil is in the foregoing description: prescription total amount 100 grams, the vegetable oil consumption is the 310-370 milliliter.
The soak time of medicine in oil can suitably be adjusted according to ambient temperature, and the measure of also can taking suitably to heat is enhanced productivity to shorten soak time.
Further specify good effect of the present invention below by one a group of clinical comparison test and a treated animal contrast test.
One, ointment of the present invention and burning hot ointment clinical comparison test:
The burn and scald patient is totally 942 examples, male's 697 examples wherein, women's 245 examples; 4 months-78 years old age, 394 examples of wherein being grown up, children's's 548 examples.Hinder level by the evaluation of " surgery " standard (a yellow tame team of four horses, second edition, Beijing people's health 1972:69 of publishing house) three degree classification method, 2 ° of burn and scald 143 examples wherein, the course of disease all is less than 4 days.942 examples are divided into ointment treatment group of the present invention and burning hot ointment matched group at random in 2: 1 ratios.
Wherein, 628 examples are organized in treatment of the present invention, male's 471 examples, and women's 157 examples, 261 examples of being grown up, children's's 367 examples all adopt ointment treatment of the present invention; Burning hot ointment matched group 314 examples, male's 226 examples, women's 88 examples, 133 examples of being grown up, children's's 181 examples all adopt commercially available burning hot ointment treatment;
To hindering reason: scald 352 examples, general burn 216 examples, chemical burn 50 examples, electric burn 10 examples, burn and scald accounts for body surface area 1%-40%, wherein 2 ° of burn and scald (comprising shallow dark), 268 examples, on average account for body surface area 7.7%, 3 ° of burn and scald 46 examples of facet on average account for 1.2%, two group of characteristic of disease contrast of body surface area no significant difference.
Medication: all cases are used 1% bromo geramine liquid successively, and normal saline cleans wound surface.Of the present invention group that ointment of the present invention is coated in the dressing about 0.2cm is thick, and bandaging is changed dressings 1 1-2 day, and dark 2-3 ° is watered and scald the patient and change every day 1 time; Matched group is by burning hot cream using method.
Observation item and standard:, observe its wound surface and stop sepage disappearing edema and curative day to two groups 2 ° (shallow dark) burn and scald the wounded; To 3 ° of burn and scald of two groups of small sizes, observe its eschar and remove time and curative day fully; Measure eschar and take off wound surface bud surface pH value when most, by " tcm diagnosis, criterion of therapeutical effect " (1988:95 of State Administration of Traditional Chinese Medicine).
The result:
It is 42 hours that 2 ° of 531 examples in of the present invention group (shallow dark) empyrosis wound surfaces stop the sepage time, and edema extinction time average 4.3 days, average cure time are 12.8 days.2 ° of matched group 268 examples (shallow dark) empyrosis wound surfaces stop 60 hours sepage time, edema extinction time average 6.2 days, average cure time 21.6 days, two groups of contrasts cure average time the P value all less than 0.01.
Eschar removes the time: 3 ° of burn and scald eschars of of the present invention group 97 example removed time average 13.5 days, and wound surface granulation pH value was 7.0-7.5 during wherein 88 routine crusts removed.3 ° of burn and scald eschars of matched group 46 examples removed time average 23.4 days, and wound surface granulation pH value was 7.0-7.5 during wherein 19 routine crusts removed, and 29 examples were failed decrustation above 25 days and adopted excision of eschar.
This group clinical comparison result of the test shows that the therapeutic effect of ointment of the present invention obviously is better than burning hot ointment.
Two, the animal contrast test of ointment of the present invention and vaseline oil yarn and burning hot ointment:
(1), ointment of the present invention and vaseline oil yarn are adjusted the comparison of wound surface pH value
With 6 groups of TWOs is subjects, infects the wound surface that its wound surface obtains different PH with different bacterium:
1st, the wound surface mean P H-number of 2 winding kind staphylococcus aureuses is 6.2;
3rd, the colibacillary wound surface mean P of 4 winding kinds H-number is 6.5;
5th, the colibacillary wound surface mean P of 6 winding kinds H-number is 8.2.
With ointment of the present invention the wound surface of the 1st, 3,5 group of TWO is applied ointment or plaster 4 times, all the pH value of wound surface transfers 7-7.5 to, wherein the 1st, 3,5 group of pH value difference average out to 7.2,7.3,7.4.
To paste the vaseline oil yarn wound surface of the 2nd, 4,6 group of TWO is applied ointment or plaster 4 times, pH value changes little, the 2nd, 4,6 group of pH value difference average out to 6.7,6.8,8.1.
1st, the transformation of forming the face pH value for 3,5 groups and the 2nd, 4,6 contrasts its P value all less than 0.01.The effect that shows the vaseline oil yarn that ointment of the present invention is more best than existing generally acknowledged adjustment wound surface pH value effect is much better.
(2), ointment of the present invention and burning hot ointment are to the comparison of zoogenetic infection wound healing time influence
With ointment of the present invention above-mentioned 1,3,5 group of TWO is treated, the average natural law that reaches healing was respectively 36.5 days, 35.4 days, 35.8 days.With burning hot ointment above-mentioned 2,4,6 groups of TWOs are treated, the average natural law that reaches healing was respectively 49.3 days, 48.7 days, 50.1 days.Obviously accelerate than matched group healing time for of the present invention group.
Test shows that also ointment of the present invention can shorten the time that stops 2-3 ° of empyrosis wound surface sepage, eliminates edema rapidly, obviously accelerates wound healing, has the protection wound surface effect of similar allo-skin graft.Can be very fast molten soft, remove 3 ° of burn and scald eschars, have precedence over the decrustation effect of cutting the crust operation.
According to interrelated data, staphylococcus aureus produces acid because of decomposing saccharide, the wound surface pH value is reduced to below 6.7, and bacillus pyocyaneus produce ammonia because of decomposing aminoacid, and the wound surface pH value is risen to more than 8.0, the wound surface bacteria containing amount is minimum when only making its pH value transfer to 7-7.5, infect the gentlyest, it is the fastest to heal, and ointment of the present invention can all transfer zoogenetic infection wound surface pH value to neutrality, have significant bactericidal action, this is the main cause that its therapeutic effect is better than other ointment greatly.
Claims (3)
1, a kind of preparation method for the treatment of the external-applied ointment of burn and scald is characterized in that, comprises the steps:
A, be ready to following prescription: Bulbus Fritillariae Cirrhosae, Endothelium Corneum Gigeriae Galli, Rhizoma Coptidis (river), Radix Et Rhizoma Rhei, Radix Arnebiae (Radix Lithospermi), Rhizoma Corydalis, Cortex Moutan, Radix Angelicae Sinensis, Sanguis Draxonis, Cera Flava, calcined akaishi cosmetics, calamine stone, Dragon bone(fried) powder, Borneolum Syntheticum powder according to proper proportion; Be equipped with the proper amount of edible vegetable oil in addition;
B, with preceding 8 flavor medicines drop into soak certain hour in the edible vegetable oils after, endure to medicine with warm fire and to drip into pearl, the elimination medicinal residues are endured and are boiled, and drop into the later Six-element medicine of Sanguis Draxonis again and stir into cream;
The percentage by weight of described prescription is: Bulbus Fritillariae Cirrhosae 6.2-10.2%, Endothelium Corneum Gigeriae Galli 3.1-5.1%, Rhizoma Coptidis (river) 10.6-16.6%, Radix Et Rhizoma Rhei 3.1-5.1%, Radix Arnebiae (Radix Lithospermi) 6.5-12.5%, Rhizoma Corydalis 6.5-12.5%, Cortex Moutan 4.1-8.1%, Radix Angelicae Sinensis 6.2-10.2%, Sanguis Draxonis 3.1-5.1%, Cera Flava 10.6-16.6%, calcined akaishi cosmetics 3.1-5.1%, calamine stone 3.1-5.1%, Dragon bone(fried) powder 6.2-10.2%, Borneolum Syntheticum powder 1.7-3.7%.
2, the preparation method of external-applied ointment according to claim 1 is characterized in that, the addition of described vegetable oil is: prescription total amount 100 grams, the vegetable oil consumption is the 310-370 milliliter.
3, the preparation method of external-applied ointment according to claim 1 is characterized in that, the soak time of preceding 8 flavor medicines in vegetable oil should suitably be adjusted into 10-14 hour according to ambient temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96111853A CN1054069C (en) | 1996-08-21 | 1996-08-21 | Preparation of external-use ointment for burn and scald |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96111853A CN1054069C (en) | 1996-08-21 | 1996-08-21 | Preparation of external-use ointment for burn and scald |
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| Publication Number | Publication Date |
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| CN1158733A CN1158733A (en) | 1997-09-10 |
| CN1054069C true CN1054069C (en) | 2000-07-05 |
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| CN96111853A Expired - Fee Related CN1054069C (en) | 1996-08-21 | 1996-08-21 | Preparation of external-use ointment for burn and scald |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1058627C (en) * | 1997-12-05 | 2000-11-22 | 湖南省向红机械厂 | Compound arnebia root paste for curing heat injury of human body and its preparing method |
| CN103083373B (en) * | 2013-01-24 | 2014-01-22 | 孙吉书 | Specific medicine for treating burns and scalds and other skin injury |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055297A (en) * | 1991-03-28 | 1991-10-16 | 许聿祥 | A kind of autofrettage of skin-moistening burn and scald medicine |
| CN1092986A (en) * | 1993-03-31 | 1994-10-05 | 熊光明 | The compound method of general universal ointment and purposes |
| CN1101858A (en) * | 1994-03-02 | 1995-04-26 | 曾涛 | Powder medicine for removing necrotic tissue and promoting muscle growing |
| CN1106697A (en) * | 1994-10-18 | 1995-08-16 | 叶太华 | Medicine for treatment of burn and scald and its preparation |
-
1996
- 1996-08-21 CN CN96111853A patent/CN1054069C/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1055297A (en) * | 1991-03-28 | 1991-10-16 | 许聿祥 | A kind of autofrettage of skin-moistening burn and scald medicine |
| CN1092986A (en) * | 1993-03-31 | 1994-10-05 | 熊光明 | The compound method of general universal ointment and purposes |
| CN1101858A (en) * | 1994-03-02 | 1995-04-26 | 曾涛 | Powder medicine for removing necrotic tissue and promoting muscle growing |
| CN1106697A (en) * | 1994-10-18 | 1995-08-16 | 叶太华 | Medicine for treatment of burn and scald and its preparation |
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| CN1158733A (en) | 1997-09-10 |
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Address after: 518002 Shenzhen Wenjin Road No. 2 stone building block A No. 1606 Applicant after: Kangzhixin Industry Development Co., Ltd., Shenzhen Address before: 1205 Zhenhua building, 99 Shennan East Road, 518001, Shenzhen Applicant before: Shenzhen Land Industry Development Co., Ltd. |
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Free format text: CORRECT: APPLICANT; FROM: SHENZHEN CITY KANGXIN INDUSTRY DEVELOPMENT CO., LTD. TO: ZENG ZHANLIN |
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Address after: 518003 Shenzhen city Futian District Nanyuan Village 7 704 Applicant after: Zeng Zhanlin Address before: 518001 Shenzhen Wenjin Road No. 2, building A, 1606 names Applicant before: Shenzhen Kang Kang Industrial Development Co., Ltd. |
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Owner name: SHENZHEN CITY FUBANG RUIBO TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: ZENG ZHANLIN Effective date: 20090710 |
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Effective date of registration: 20090710 Address after: Room 18F, building 2, Southland building, Hongling Middle Road, Hongling, Shenzhen, Guangdong, Futian District Patentee after: Shenzhen City Fu Ruibo Technology Co. Ltd. to help Address before: Futian District Nanyuan village in Shenzhen province Guangdong city 7 Building 604 Patentee before: Zeng Zhanlin |
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Correction item: Patentee Correct: Shenzhen City Fubon Ruibo Technology Co. Ltd. False: Shenzhen City Fu Ruibo Technology Co. Ltd. to help Number: 33 Page: 2014 Volume: 25 |
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Free format text: CORRECT: PATENTEE; FROM: SHENZHEN CITY FUBANG RUIBO TECHNOLOGY CO., LTD. TO: SHENZHEN CITY FUBANG RUIBO SCIENCE CO., LTD. |
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Owner name: SHENZHEN FUBANG RUIBO PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: SHENZHEN FUBANG RUIBO TECHNOLOGY CO., LTD. Effective date: 20111111 |
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Effective date of registration: 20111111 Address after: Nanshan District Shenzhen City, Guangdong Province, 518000 North Road No. 9116 Fu technology building B block two layer Patentee after: Shenzhen City Fubon Ruibo Pharmaceutical Co. Ltd. Address before: 518008, 18F, room 2, Southland building, Hongling Middle Road, Hongling, Shenzhen, Guangdong, Futian District Patentee before: Shenzhen City Fubon Ruibo Technology Co. Ltd. |
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