CN108524878A - A kind of skin care antiphlogistine and preparation method thereof for treating burn and scald - Google Patents

A kind of skin care antiphlogistine and preparation method thereof for treating burn and scald Download PDF

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Publication number
CN108524878A
CN108524878A CN201810791437.XA CN201810791437A CN108524878A CN 108524878 A CN108524878 A CN 108524878A CN 201810791437 A CN201810791437 A CN 201810791437A CN 108524878 A CN108524878 A CN 108524878A
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skin care
antiphlogistine
scald
treating burn
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宋运杰
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Lixin County Yun Jie Family Farm
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Lixin County Yun Jie Family Farm
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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Abstract

The invention discloses a kind of skin care antiphlogistines and preparation method thereof for treating burn and scald, are mainly prepared by Radix Sangusorbae, rheum officinale, the coptis, lactogenesis perfume, Myrrha, trigone, curcuma zedoary, ilex pubescens, rice shell, Asian puccoon, eye of wind grass, folium artemisiae argyi, Chinese gall, Os Draconis, licorice and Cortex Phellodendri;Good effect of the present invention, quick, safe without toxic side effect, have anti-inflammatory analgetic, it is promoting blood circulation and removing blood stasis, clearing heat and detoxicating, remove necrosis and promote granulation, remove eliminating dampness, convergence wound and other effects, the skin of necrosis can be allowed to form a scab rapidly regeneration.

Description

A kind of skin care antiphlogistine and preparation method thereof for treating burn and scald
Technical field
The invention belongs to field of traditional Chinese medicine technology, and in particular to a kind of skin care antiphlogistine that treating burn and scald and its preparation Method.
Background technology
Burn and scald refer to because of the effects that boiling water (oil), raging fire, light, electricity, radioactive ray or chemical substance in human body caused by Damage, it includes skin or mucosa injury, and severe patient may injure subcutaneous tissue, is day such as muscle, bone, joint even internal organ Most common and extremely complex one of injury in often work and life.It is injured with the continuous expansion in social life space Number rises year by year, especially children and adolescents and the elderly.According to statistics, there are about 20,000,000 people by different journeys every year in China Degree burn, accounts for the 1.5%~2.0% of total population, wherein number of hospitalized accounts for 5.0%.At present treatment burn and scald chemicals compared with More, such as antibacterials, silver salt, main function is anti-inflammatory, antibacterial, analgesia, but there are certain adverse reaction, to deep burn The surface of a wound promote skin tissue Regenerated energy force difference, treat burnt degree consumer edema effect it is undesirable the deficiencies of place.
Invention content
According to the above-mentioned deficiencies of the prior art, the technical problem to be solved by the present invention is to propose a kind of to treat burn and scald Skin care antiphlogistine and preparation method thereof, in order to solve the above-mentioned technical problem, the technical solution adopted by the present invention is:
A kind of skin care antiphlogistine for treating burn and scald includes mainly:Radix Sangusorbae, rheum officinale, the coptis, lactogenesis perfume, Myrrha, three Rib, curcuma zedoary, ilex pubescens, rice shell, Asian puccoon, eye of wind grass, folium artemisiae argyi, Chinese gall, Os Draconis, licorice, Cortex Phellodendri.
Preferably, it is prepared from the following raw materials in parts by weight:9.5-10.5 grams of Radix Sangusorbae, 29.5-30.5 grams of rheum officinale, the coptis 19.5-20.5 grams, 14.5-15.5 grams of lactogenesis perfume (or spice), 14.5-15.5 grams of Myrrha, 9.5-10.5 grams of trigone, curcuma zedoary 9.5-10.5 Gram, 29.5-30.5 grams of ilex pubescens, 29.5-30.5 grams of meter shell, 499-501 grams of Asian puccoon, 29.5-30.5 grams of eye of wind grass, folium artemisiae argyi 29.5-30.5 grams, 14.5-15.5 grams of Chinese gall, 29.5-30.5 grams of Os Draconis, 9.5-10.5 grams of licorice, Cortex Phellodendri 9.5-10.5 Gram.
Preferably, it is prepared from the following raw materials in parts by weight:10 grams of Radix Sangusorbae, 20 grams of rheum officinale, 20 grams of the coptis, lactogenesis perfume (or spice) 15 Gram, 15 grams of Myrrha, 10 grams of trigone, 10 grams of curcuma zedoary, 30 grams of 30 gram, meter shell of ilex pubescens, 500 grams of Asian puccoon, the eye of wind careless 30 grams, folium artemisiae argyi 30 grams, 15 grams of Chinese gall, 30 grams of Os Draconis, 10 grams of licorice, 10 grams of Cortex Phellodendri.
A kind of preparation method of skin care antiphlogistine that treating burn and scald, includes the following steps:
(1) Radix Sangusorbae, rheum officinale, the coptis, lactogenesis perfume, Myrrha, trigone, curcuma zedoary, ilex pubescens, rice shell, purple are weighed by quality 3000 grams of sesame oil are added in grass, eye of wind grass, folium artemisiae argyi, Chinese gall, Os Draconis, licorice, Cortex Phellodendri, after impregnating 48 hours, heat big fire It decocts 3-4 hours, filters, obtain medicine oil, liquid and the dregs of a decoction;
(2) liquid is reheated through adsorption clarification, medicine oil, adds beeswax, and 20 grams of beeswax, medicine is added in every 100 grams of medicine oils Oily centrifugal concentrating is at the concentrate that density is 1.20-1.35;
(3) when medicine oil is cooled to 30-35 DEG C, 3% borneol crushed is added while stirring, is sealed after stirring evenly It is canned to get skin care anti-inflammatory paste.
Preferably, the application method is that paste final drug is applied with the surface of a wound with the thickness of 0.5mm-1.0mm, one day three It is secondary, have when fester, bubble or slough first that cleaning or debridement, rear yarn cloth wrap very thin absorbent cotton, absorbent cotton is stained with this hair Bright skin care antiphlogistine, is sticked, dressing after bandaging 24 hours.
Compared with prior art, beneficial effects of the present invention:
1. the raw material of the present invention is generally easy to get and cheap, preparation process is simple, easy to operate, is suitable for extensive Industrialized production.
2. good effect of the present invention, quick, safe without toxic side effect, have anti-inflammatory analgetic, it is promoting blood circulation and removing blood stasis, clearing heat and detoxicating, It removes necrosis and promote granulation, remove eliminating dampness, convergence wound and other effects, the skin of necrosis can be allowed to form a scab rapidly regeneration, disappeared especially for burn and scald It is swollen quick.
3, the present invention is fast with town pain, resistance infection is strong, stronger bacteriostasis, effectively body fluid can be inhibited to exosmose, effectively Reduce the formation of pigmentation and scar.
Specific implementation mode
It below by the description to embodiment, is described in further detail, to help those skilled in the art to this hair Bright inventive concept, technical solution have more complete, accurate and deep understanding.
Embodiment 1
(1) 15 grams fragrant 10 grams of Radix Sangusorbae, 20 grams of rheum officinale, 20 grams of the coptis, lactogenesis, 15 grams of Myrrha, 10 grams of trigone, cowherb are weighed 10 grams of art, 30 grams of 30 gram, meter shell of ilex pubescens, 500 grams of Asian puccoon, 30 grams of eye of wind grass, 30 grams of folium artemisiae argyi, 15 grams of Chinese gall, Os Draconis 30 Gram, 10 grams of licorice, 10 grams of Cortex Phellodendri, 3000 grams of sesame oil of addition, after impregnating 48 hours, heating big fire decocts 3.5 hours, filters, obtains Medicine oil, liquid and the dregs of a decoction;
(2) liquid is reheated through adsorption clarification, medicine oil, adds beeswax, and 20 grams of beeswax, medicine is added in every 100 grams of medicine oils The concentrate that oily centrifugal concentrating is 1.30 at density;
(3) when medicine oil is cooled to 35 DEG C, 3% borneol crushed is added while stirring, stirs evenly rear hermetically sealed can Dress is to get skin care anti-inflammatory paste.
Application method is that paste final drug is applied with the surface of a wound with the thickness of 0.5mm-1.0mm to have purulence three times a day First cleaning or debridement when liquid, bubble or slough, rear yarn cloth wrap very thin absorbent cotton, and absorbent cotton is stained with the skin care anti-inflammatory of the present invention Cream sticks, dressing after bandaging 24 hours.
Embodiment 2
(1) 14.5 grams fragrant 9.5 grams of Radix Sangusorbae, 19.5 grams of rheum officinale, 19.5 grams of the coptis, lactogenesis, 14.5 grams of Myrrha, three are weighed 9.5 grams of rib, 9.5 grams of curcuma zedoary, 29.5 grams of 29.5 gram, meter shell of ilex pubescens, 499 grams of Asian puccoon, the eye of wind grass 29.5 grams, 29.5 grams of folium artemisiae argyi, 14.5 grams of Chinese gall, 29.5 grams of Os Draconis, 9.5 grams of licorice, Cortex Phellodendri 9.5 grams of additions, 3000 grams of sesame oil add after impregnating 48 hours Hot big fire decocts 3 hours, and filtering obtains medicine oil, liquid and the dregs of a decoction;
(2) liquid is reheated through adsorption clarification, medicine oil, adds beeswax, and 20 grams of beeswax, medicine is added in every 100 grams of medicine oils The concentrate that oily centrifugal concentrating is 1.20 at density;
(3) when medicine oil is cooled to 30 DEG C, 3% borneol crushed is added while stirring, stirs evenly rear hermetically sealed can Dress is to get skin care anti-inflammatory paste.
Application method is the same as embodiment 1.
Embodiment 3
(1) weigh 15.5 grams fragrant 10.5 grams of Radix Sangusorbae, 20.5 grams of rheum officinale, 20.5 grams of the coptis, lactogenesis, 15.5 grams of Myrrha, 10.5 grams of trigone, 10.5 grams of curcuma zedoary, 30.5 grams of 30.5 gram, meter shell of ilex pubescens, 501 grams of Asian puccoon, the eye of wind careless 30.5 grams, folium artemisiae argyi 30.5 Gram, 15.5 grams of Chinese gall, 30.5 grams of Os Draconis, 10.5 grams of licorice, 10.5 grams of Cortex Phellodendri, 3000 grams of sesame oil of addition, impregnate 48 hours Afterwards, heating big fire decocts 4 hours, filters, obtains medicine oil, liquid and the dregs of a decoction;
(2) liquid is reheated through adsorption clarification, medicine oil, adds beeswax, and 20 grams of beeswax, medicine is added in every 100 grams of medicine oils The concentrate that oily centrifugal concentrating is 1.35 at density;
(3) when medicine oil is cooled to 35 DEG C, 3% borneol crushed is added while stirring, stirs evenly rear hermetically sealed can Dress is to get skin care anti-inflammatory paste.
Application method is the same as embodiment 1.
Clinical trial:
(1) clinical data:240 scald patients of the present inventor couple carry out clinical observation treatment, wherein man 120, female 120 Example, the age is between 20-65 Sui.Be randomly divided into 4 groups, every group of 60 people, first three groups are experimental group, the 4th group be control group, four groups In gender, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), it is comparable.
(2) therapy:Experimental group first three groups use the skin care antiphlogistine of 1-3 of the embodiment of the present invention, application method respectively For paste final drug is applied with the surface of a wound with the thickness of 0.5mm-1.0mm, three times a day, there are fester, bubble or downright bad group First cleaning or debridement when knitting, rear yarn cloth wrap very thin absorbent cotton, and absorbent cotton is stained with the skin care antiphlogistine of the present invention, sticks, bandage Dressing after 24 hours.15 days courses for the treatment of, the 4th group is control group, and control group smears other drugs, as traumatology spirit is sprayed The conventional medications such as mist agent, scald oil.Experimental group and control group persistently use 3 courses for the treatment of respectively.During treatment to four groups of patients into Row is observed continuously, and records symptom and variation.
(3) curative effect determinate standard:
It cures:The surface of a wound heals completely, no infection, and non-pigment is calm, no longer pain, preventing from scar.
It is effective:90% or more wound healing, there is slight pigmentation, no longer pain, and there are a little scars.
Effectively:50% or more wound healing, has pigmentation, pain relief, there are scars.
In vain:Trauma surface infestation fails to control, and pain does not mitigate, and there are scars.
(4) clinical effectiveness:
Experimental group:Clinical cure 100 (55.5%), it is effective 66 (36.7%), it is effective 10 (5.6%), it is total effective Rate is 97.8%.Control group:It cures 3 (5%), effective 10 (16.7%), effective 15 (25%), total effective rate is 46.7%;It can be seen that the with obvious effects of experimental group is higher than control group.
Model case:
Guo, man, 45 years old, accidentally falls down, left foot anterolateral crural is scalded by exhaust pipe, and wound has 5 lis by motorcycle Rice or so, removes hospital admission, after hospitalize for a period of time, locally festers, use up ointment for treating burn on the market in time at that time, It does not all take effect, very thin absorbent cotton is wrapped with gauze, be stained with 2 ointment of the embodiment of the present invention, stick, bandage.Second night When dressing is opened, tape removes the rotten meat of a big layer.Part is there remains to rot meat, it is cleaned it is complete after, give his dressing, wrapping It is good.The evening dressing of third day, when opening, the meat that rots all is removed, the 4th day, and most of contraction of wounds is shown in surplus three centimetres or so The wound of side.Dressing is adhered to daily, and whole rehabilitations in the 12nd day, wound there is not scar, the affected part colour of skin newer.
Chen, female, 56 years old, when burning down boiling water, the when of falling boiling water, was accidentally spread on foot, caused the big face of instep Product scald, instep is swollen with after one day, has played bubble, and with other medicament for treating scald without what effect, very thin absorbent cotton is wrapped with gauze, It is stained with the ointment of the embodiment of the present invention 1, is sticked, is bandaged.Find that bubble has been broken, and is continuing with 5 days when dressing in second day It was found that scald part has been formed a scab, scar has fallen off after 10 days, fully recovers.
Zhang, man, 47 years old, because of gas leakage, explodes, right hand arm large-area burns are wrapped very thin with gauze Absorbent cotton is stained with 3 ointment of the embodiment of the present invention, sticks, bandage.When dressing in second day, black dead skin, third are stained on cotton yarn When its dressing, the carrion of burn is also removed, and finds after 15 days to have grown new meat, though having uneven, has been fully recovered after 30 days.
The present invention is exemplarily described above in conjunction with specific embodiment, it is clear that the present invention implements not by upper The limitation of mode is stated, if the improvement of the various unsubstantialities of inventive concept and technical scheme of the present invention progress is used, or It is not improved by the present invention design and technical solution directly apply to other occasions, protection scope of the present invention it It is interior.Protection scope of the present invention should be determined by the scope of protection defined in the claims.

Claims (5)

1. a kind of skin care antiphlogistine for treating burn and scald, which is characterized in that include mainly:Radix Sangusorbae, rheum officinale, the coptis, lactogenesis be fragrant, Myrrha, trigone, curcuma zedoary, ilex pubescens, rice shell, Asian puccoon, eye of wind grass, folium artemisiae argyi, Chinese gall, Os Draconis, licorice, Cortex Phellodendri.
2. a kind of skin care antiphlogistine for treating burn and scald according to claim 1, which is characterized in that by following weight proportion Raw material be made:9.5-10.5 grams of Radix Sangusorbae, 29.5-30.5 grams of rheum officinale, 19.5-20.5 grams of the coptis, lactogenesis perfume (or spice) 14.5-15.5 Gram, 14.5-15.5 grams of Myrrha, 9.5-10.5 grams of trigone, 9.5-10.5 grams of curcuma zedoary, 29.5-30.5 grams of ilex pubescens, meter shell 29.5-30.5 grams, 499-501 grams of Asian puccoon, 29.5-30.5 grams of eye of wind grass, 29.5-30.5 grams of folium artemisiae argyi, Chinese gall 14.5-15.5 Gram, 29.5-30.5 grams of Os Draconis, 9.5-10.5 grams of licorice, 9.5-10.5 grams of Cortex Phellodendri.
3. a kind of skin care antiphlogistine for treating burn and scald according to claim 1, which is characterized in that by following weight proportion Raw material be made:10 grams of Radix Sangusorbae, 20 grams of rheum officinale, 20 grams of the coptis, 15 grams of lactogenesis perfume, 15 grams of Myrrha, 10 grams of trigone, curcuma zedoary 10 Gram, it is 30 grams of 30 gram, meter shell of ilex pubescens, 500 grams of Asian puccoon, 30 grams of eye of wind grass, 30 grams of folium artemisiae argyi, 15 grams of Chinese gall, 30 grams of Os Draconis, raw 10 grams of Radix Glycyrrhizae, 10 grams of Cortex Phellodendri.
4. a kind of preparation method of skin care antiphlogistine for treating burn and scald according to any one of claim 1-3, It is characterized in that, includes the following steps:
(1) Radix Sangusorbae, rheum officinale, the coptis, lactogenesis perfume, Myrrha, trigone, curcuma zedoary, ilex pubescens, rice shell, Asian puccoon, wind are weighed by quality Eye grass, folium artemisiae argyi, Chinese gall, Os Draconis, licorice, Cortex Phellodendri, are added 3000 grams of sesame oil, and after impregnating 48 hours, heating big fire decocts 3-4 hours, filtering obtained medicine oil, liquid and the dregs of a decoction;
(2) liquid is reheated through adsorption clarification, medicine oil, adds beeswax, and every 100 grams of medicine oils are added 20 grams of beeswax, medicine oil from The heart is condensed into the concentrate that density is 1.20-1.35;
(3) when medicine oil is cooled to 30-35 DEG C, 3% borneol crushed is added while stirring, stirs evenly rear hermetically sealed can Dress is to get skin care anti-inflammatory paste.
5. a kind of skin care antiphlogistine for treating burn and scald according to claim 1, which is characterized in that the application method is Paste final drug is applied with the surface of a wound with the thickness of 0.5mm-1.0mm has fester, bubble or slough three times a day When first cleaning or debridement, rear yarn cloth wrap very thin absorbent cotton, absorbent cotton is stained with the skin care antiphlogistine of the present invention, sticks, bandages 24 Dressing after hour.
CN201810791437.XA 2018-07-18 2018-07-18 A kind of skin care antiphlogistine and preparation method thereof for treating burn and scald Pending CN108524878A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1207318A (en) * 1998-08-13 1999-02-10 王新民 Ointment for treating burn and scald
CN102258746A (en) * 2011-06-29 2011-11-30 李宏干 Ointment for treating surface of burns and scalds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1207318A (en) * 1998-08-13 1999-02-10 王新民 Ointment for treating burn and scald
CN102258746A (en) * 2011-06-29 2011-11-30 李宏干 Ointment for treating surface of burns and scalds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
孙继青等: "京万红治疗输液所致静脉炎的疗效观察", 《护士进修杂志》 *

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Application publication date: 20180914