CN105392811B - 粉末聚合物、其制备方法及其用作增稠剂的用途 - Google Patents

粉末聚合物、其制备方法及其用作增稠剂的用途 Download PDF

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CN105392811B
CN105392811B CN201480041310.6A CN201480041310A CN105392811B CN 105392811 B CN105392811 B CN 105392811B CN 201480041310 A CN201480041310 A CN 201480041310A CN 105392811 B CN105392811 B CN 105392811B
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CN105392811A (zh
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O·布朗
P·马洛
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PROD POUR LES IND CHIMIQUES SE
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PROD POUR LES IND CHIMIQUES SE
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16—Organic material
    • B01J39/18—Macromolecular compounds
    • B01J39/20—Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/58—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-(meth)acryloylmorpholine
    • C08F220/585—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing oxygen in addition to the carbonamido oxygen, e.g. N-methylolacrylamide, N-(meth)acryloylmorpholine and containing other heteroatoms, e.g. 2-acrylamido-2-methylpropane sulfonic acid [AMPS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/48—Thickener, Thickening system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54—Polymers characterized by specific structures/properties
    • A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
    • A61K2800/5424—Polymers characterized by specific structures/properties characterized by the charge anionic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C08F220/1812—C12-(meth)acrylate, e.g. lauryl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C08F220/1818—C13or longer chain (meth)acrylate, e.g. stearyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/20—Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/103—Esters of polyhydric alcohols or polyhydric phenols of trialcohols, e.g. trimethylolpropane tri(meth)acrylate

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
CN201480041310.6A 2013-07-24 2014-07-18 粉末聚合物、其制备方法及其用作增稠剂的用途 Active CN105392811B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1357280 2013-07-24
FR1357280A FR3008981B1 (fr) 2013-07-24 2013-07-24 Nouveau polymere en poudre, procede pour sa preparation et utilisation comme epaississant
PCT/FR2014/051851 WO2015011380A1 (fr) 2013-07-24 2014-07-18 Nouveau polymère en poudre, procédé pour sa préparation et utilisation comme épaississant

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CN105392811A CN105392811A (zh) 2016-03-09
CN105392811B true CN105392811B (zh) 2019-03-08

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Country Link
US (1) US10035143B2 (enExample)
EP (1) EP3024859B1 (enExample)
JP (1) JP6370378B2 (enExample)
KR (1) KR102196342B1 (enExample)
CN (1) CN105392811B (enExample)
FR (1) FR3008981B1 (enExample)
WO (1) WO2015011380A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10159638B2 (en) 2016-06-21 2018-12-25 Johnson & Johnson Consumer Inc. Personal care compositions containing complexing polyelectrolytes
CN109957062A (zh) * 2017-12-22 2019-07-02 万华化学（宁波）有限公司 高交联丙烯酸酯类共聚物及其制备方法和作为增稠剂的用途
FR3078709B1 (fr) * 2018-03-06 2020-02-28 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Latex inverse auto-inversible epaississant comprenant comme agent inverseur des especes tensioactives de la famille des esters de polyglycerols, et les compositions en comprenant
FR3078708B1 (fr) * 2018-03-06 2020-03-27 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Latex inverse auto-inversible, comprenant comme agent inverseur des especes tensioactives de la famille des esters de polyglycerols, son utilisation comme agent epaississant et compositions aqueuses liquides detergentes a usage menager ou industriel aqueuse en comprenant
EP3610853A1 (en) 2018-08-15 2020-02-19 The Boots Company PLC Cosmetic compositions
FR3099368B1 (fr) 2019-07-31 2022-08-19 Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic Composition cosmétique sous la forme d’une poudre compacte, résistante aux chocs
WO2022173974A1 (en) * 2021-02-10 2022-08-18 TRI-K Industries, Inc. A novel composition and method containing pea and quinoa natural peptides and niacinamide to enhance skin glow, radiance and even skin tone

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0750899A2 (en) * 1995-06-30 1997-01-02 Shiseido Company Limited An emulsifier or solubilizer which consists of a water soluble amphiphilic polyelectrolyte, and an emulsified composition or a solubilized composition and an emulsified cosmetic or a solubilized cosmetic containing it
WO2004063228A1 (en) * 2003-01-09 2004-07-29 Lamberti Spa Synthetic thickeners for cosmetics
CN1869080A (zh) * 2005-05-25 2006-11-29 化工产品开发公司Seppic Amps和n,n－二甲基丙烯酰胺的共聚物的新的反型胶乳；化妆品用途
CN102548532A (zh) * 2009-09-11 2012-07-04 化工产品开发公司Seppic 新型粉末状聚合物，其制备方法以及作为增稠剂的应用
CN103228258A (zh) * 2010-12-02 2013-07-31 化工产品开发公司Seppic 可在宽pH范围使用的新型阳离子增稠剂，其制备方法和包含它的组合物

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2798053A (en) 1952-09-03 1957-07-02 Goodrich Co B F Carboxylic polymers
DE2638386A1 (de) 1976-08-26 1978-03-02 Basf Ag Wasserloesliche, haertbare acrylharz- copolymere, verfahren zu ihrer herstellung und ihre verwendung
US4170563A (en) * 1977-08-12 1979-10-09 Eastman Kodak Company Liquid electrographic developer comprising polymeric phosphonate dispersing agent
JPS5431738A (en) * 1977-08-12 1979-03-08 Eastman Kodak Co Liquid electrophotographic developer
EP0301532A3 (en) 1987-07-30 1989-10-18 The B.F. Goodrich Company Solvent free acrylic acid type thickening agents and a method of making same
GB9104878D0 (en) * 1991-03-08 1991-04-24 Scott Bader Co Thickeners for personal care products
DE4209632A1 (de) 1992-03-25 1993-09-30 Basf Ag Sulfogruppenhaltige Polymere
US5288814A (en) 1992-08-26 1994-02-22 The B. F. Goodrich Company Easy to disperse polycarboxylic acid thickeners
JPH09136826A (ja) * 1995-11-15 1997-05-27 Shiseido Co Ltd 水溶性架橋型両親媒性高分子電解質からなる可溶化剤、これを配合した可溶化組成物及び可溶化化粧料
JPH09141080A (ja) * 1995-11-15 1997-06-03 Shiseido Co Ltd 水溶性架橋型両親媒性高分子電解質からなる乳化剤、これを配合した乳化組成物及び乳化化粧料
DE19625810A1 (de) 1996-06-28 1998-01-02 Hoechst Ag Wasserlösliche oder wasserquellbare Polymerisate
JPH1112511A (ja) * 1997-06-27 1999-01-19 Mitsubishi Chem Corp 記録液
ES2674247T3 (es) 1998-01-16 2018-06-28 Societe D'exploitation De Produits Pour Les Industries Chimiques, S.E.P.P.I.C. Composición cosmética espesada con un látex
DE50015912D1 (de) 1999-07-15 2010-06-10 Clariant Produkte Deutschland Wasserlösliche Polymere und ihre Verwendung in kosmetischen und pharmazeutischen Mitteln
DE10000648A1 (de) 2000-01-11 2001-07-12 Clariant Gmbh Wasserlösliche oder wasserquellbare vernetzte Copolymere
FR2807046B1 (fr) 2000-03-29 2003-01-03 Seppic Sa Nouveau polymere, procede de preparation, utilisation comme epaississant et/ou emulsionnant et composition en comprenant
FR2856691B1 (fr) 2003-06-26 2005-08-26 Seppic Sa Nouveau polymere en poudre, procede pour sa preparation et utilisation comme epaississant
FR2879607B1 (fr) 2004-12-16 2007-03-30 Seppic Sa Nouveaux latex inverse concentre, procede pour sa preparation, et utilisation dans l'industrie
DE602006000979T2 (de) * 2005-06-29 2009-05-28 Rohm And Haas Co. Verdickungsmittel für wässrige Systeme
FR2933096B1 (fr) 2008-06-27 2010-08-20 Seppic Sa Nouveaux latex inverses sur des ethers d'alcools gras, compositions cosmetiques, dermocosmetiques, dermopharmaceutiques ou pharmaceutiques en comportant

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0750899A2 (en) * 1995-06-30 1997-01-02 Shiseido Company Limited An emulsifier or solubilizer which consists of a water soluble amphiphilic polyelectrolyte, and an emulsified composition or a solubilized composition and an emulsified cosmetic or a solubilized cosmetic containing it
WO2004063228A1 (en) * 2003-01-09 2004-07-29 Lamberti Spa Synthetic thickeners for cosmetics
CN1869080A (zh) * 2005-05-25 2006-11-29 化工产品开发公司Seppic Amps和n,n－二甲基丙烯酰胺的共聚物的新的反型胶乳；化妆品用途
CN102548532A (zh) * 2009-09-11 2012-07-04 化工产品开发公司Seppic 新型粉末状聚合物，其制备方法以及作为增稠剂的应用
CN103228258A (zh) * 2010-12-02 2013-07-31 化工产品开发公司Seppic 可在宽pH范围使用的新型阳离子增稠剂，其制备方法和包含它的组合物

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Publication number Publication date
WO2015011380A1 (fr) 2015-01-29
US20160167040A1 (en) 2016-06-16
KR102196342B1 (ko) 2020-12-29
EP3024859A1 (fr) 2016-06-01
EP3024859B1 (fr) 2019-03-27
US10035143B2 (en) 2018-07-31
JP6370378B2 (ja) 2018-08-08
CN105392811A (zh) 2016-03-09
KR20160037891A (ko) 2016-04-06
FR3008981A1 (fr) 2015-01-30
JP2016525606A (ja) 2016-08-25
FR3008981B1 (fr) 2016-11-18

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