CN105381142A - Traditional Chinese medicine composition for treating hyperplasia of mammary glands - Google Patents

Traditional Chinese medicine composition for treating hyperplasia of mammary glands Download PDF

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Publication number
CN105381142A
CN105381142A CN201510900967.XA CN201510900967A CN105381142A CN 105381142 A CN105381142 A CN 105381142A CN 201510900967 A CN201510900967 A CN 201510900967A CN 105381142 A CN105381142 A CN 105381142A
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parts
chinese medicine
radix
medicine composition
traditional chinese
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CN201510900967.XA
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欧小宇
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/413Gall bladder; Bile
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)

Abstract

The invention discloses a traditional Chinese medicine composition for treating hyperplasia of mammary glands. The traditional Chinese medicine composition is mainly composed of the following raw materials in parts by weight: 15 to 20 parts of radix bupleuri, 10 to 12 parts of root of kudzu vine, 6 to 10 parts of spatholobus stem, 15 to 25 parts of ligusticum wallichii, 10 to 20 parts of white peony root, 15 to 25 parts of Chinese angelica, 10 to 20 parts of cowherb seed, 10 to 15 parts of cyperus rotundus, 3 to 5 parts of white quartz, 10 to 15 parts of corydalis tuber, 1 to 3 parts of bear gall powder, 15 to 20 parts of flying squirrel feces, and 10 to 15 parts of frankincense.

Description

A kind of Chinese medicine composition for the treatment of cyclomastopathy
Technical field
The present invention relates to the field of Chinese medicines, specifically a kind of Chinese medicine being used for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy (hyperplasticdiseaseofbreast, HDB) be the general name of the class disease changed for basic pathology with the Epithelial cell of mammary gland alveolus, conduit and connective tissue proliferation, being a kind of neither the tumor noninflammatory breast lesion that is special disease with mastalgia and lump in breast again, is the modal cystic hyperplasia of breast of women.About there is the women of 70%-80% to have cyclomastopathy in various degree according to investigations, be more common in the women in 25-45 year.Clinical main manifestations is one-sided or that size appears in bilateral breast, form differs mass, and companion local distending pain, string pain or dull pain, its form, size and hardness, affect by factors such as menstrual cycle, emotion, fatigues.
The method of current treatment cyclomastopathy has a lot, conventional Western medicine, as oral hormone class medicine or by operative treatment, although oral hormone class medicine can alleviate some symptoms, is singly difficult to reach the object of thoroughly curing, drug side effect is large, and likely increases its canceration.Treatment by Chinese herbs is based on dispersing the stagnated live-QI to relieve the stagnation of QI, eliminating stagnation blood stasis dispelling, and clinical common medicine has ease pill, BUPIXIAO PIAN and Xiaojin Capsules, though these medicines have curative effect in various degree, it is long to improve the symptom time, and general cure rate is low.
Summary of the invention
The object of the invention is for people provide a kind of, to there is blood circulation promoting and blood stasis dispelling, dredge the Chinese medicine of the treatment cyclomastopathy of effect of newborn network.
The technical scheme realizing the object of the invention is:
Be used for the treatment of a Chinese medicine for cyclomastopathy, the raw material primarily of following weight parts proportioning is made:
Radix Bupleuri 15-20 part, Radix Puerariae 10-12 part, Caulis Spatholobi 6-10 part, Rhizoma Chuanxiong 15-25 part, Radix Paeoniae Alba 10-20 part, Radix Angelicae Sinensis 15-25 part, Semen Vaccariae 10-20 part, Rhizoma Cyperi 10-15 part, Quartz Album 3-5 part, Rhizoma Corydalis 10-15 part, Fel Ursi powder 1-3 part, Oletum Trogopterori 15-20 part, Olibanum 10-15 part.
Further, the weight of each raw material is:
Radix Bupleuri 18 parts, Radix Puerariae 11 parts, Caulis Spatholobi 8 parts, Rhizoma Chuanxiong 20 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 20 parts, Semen Vaccariae 15 parts, Rhizoma Cyperi 12 parts, Quartz Album 4 parts, Rhizoma Corydalis 12 parts, Fel Ursi powder 2 parts, Oletum Trogopterori 18 parts, Olibanum 12 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 40-45min, merges decoction liquor, filter and remove residue, it is the extractum of 1.10-1.30 that filtrate is concentrated into relative density at 55-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
13 kinds of natural Chinese medicine scientific compatibility chosen by the medicine that the present invention is used for the treatment of cyclomastopathy, and formula is simple, and each crude drug synergism plays blood circulation promoting and blood stasis dispelling, dredges the effect of newborn network, and instant effect, has no side effect, and its preparation method is simple, taking convenience.
Detailed description of the invention
Below in conjunction with embodiment, content of the present invention is further described, but is not limitation of the invention.
Embodiment 1
Be used for the treatment of a Chinese medicine for cyclomastopathy, the proportioning of crude drug is:
Radix Bupleuri 150g, Radix Puerariae 100g, Caulis Spatholobi 60g, Rhizoma Chuanxiong 150g, Radix Paeoniae Alba 100g, Radix Angelicae Sinensis 150g, Semen Vaccariae 100g, Rhizoma Cyperi 100g, Quartz Album 30g, Rhizoma Corydalis 100g, Fel Ursi powder 10g, Oletum Trogopterori 150g, Olibanum 100g.
Preparation method is as follows: be placed in container by the mixing of above-mentioned raw materials medicine, then add the soak by water 3 times of material quantity weight 10 times, decoct 40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.10 that filtrate is concentrated into relative density at 55 DEG C, add adjuvant, make tablet, every sheet 0.3g.
Embodiment 2
Be used for the treatment of a Chinese medicine for cyclomastopathy, the proportioning of crude drug is: Radix Bupleuri 200g, Radix Puerariae 120g, Caulis Spatholobi 80g, Rhizoma Chuanxiong 200g, Radix Paeoniae Alba 150g, Radix Angelicae Sinensis 200g, Semen Vaccariae 150g, Rhizoma Cyperi 120g, Quartz Album 50g, Rhizoma Corydalis 150g, Fel Ursi powder 30g, Oletum Trogopterori 180g, Olibanum 120g.
Preparation method is as follows: be placed in container by the mixing of above-mentioned raw materials medicine, then add the soak by water 3 times of material quantity weight 15 times, decoct 45min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 55 DEG C, add adjuvant, make granule, every 0.3g.
Embodiment 3
Be used for the treatment of a Chinese medicine for cyclomastopathy, the proportioning of crude drug is:
Radix Bupleuri 180g, Radix Puerariae 110g, Caulis Spatholobi 100g, Rhizoma Chuanxiong 250g, Radix Paeoniae Alba 200g, Radix Angelicae Sinensis 250g, Semen Vaccariae 200g, Rhizoma Cyperi 150g, Quartz Album 50g, Rhizoma Corydalis 120g, Fel Ursi powder 20g, Oletum Trogopterori 200g, Olibanum 150g.
Preparation method is as follows: be placed in container by the mixing of above-mentioned raw materials medicine, then add the soak by water 3 times of material quantity weight 20 times, decoct 40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 55 DEG C, add adjuvant, make pill, every 0.3g.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, selecting 600 examples of accepting for medical treatment in patient, clinical observation is carried out to the curative effect of medicine of the present invention.Age 20-49 year, be divided into 4 groups at random, often organize 150 example, be respectively experimental group 1-4 group.
Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 3 times, and each 4 slices/for oral administration, within one week, be a course for the treatment of, the course for the treatment of is 2 weeks.Wherein cure 472 examples, effective 87 examples, invalid 41 examples, cure rate 79%, effective percentage 94%.

Claims (2)

1. be used for the treatment of a Chinese medicine for cyclomastopathy, it is characterized in that, the raw material primarily of following weight parts proportioning is made: Radix Bupleuri 15-20 part, Radix Puerariae 10-12 part, Caulis Spatholobi 6-10 part, Rhizoma Chuanxiong 15-25 part, Radix Paeoniae Alba 10-20 part, Radix Angelicae Sinensis 15-25 part, Semen Vaccariae 10-20 part, Rhizoma Cyperi 10-15 part, Quartz Album 3-5 part, Rhizoma Corydalis 10-15 part, Fel Ursi powder 1-3 part, Oletum Trogopterori 15-20 part, Olibanum 10-15 part.
2. a kind of Chinese medicine being used for the treatment of cyclomastopathy according to claim 1, is characterized in that, the weight of each raw material is: Radix Bupleuri 18 parts, Radix Puerariae 11 parts, Caulis Spatholobi 8 parts, Rhizoma Chuanxiong 20 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 20 parts, Semen Vaccariae 15 parts, Rhizoma Cyperi 12 parts, Quartz Album 4 parts, Rhizoma Corydalis 12 parts, Fel Ursi powder 2 parts, Oletum Trogopterori 18 parts, Olibanum 12 parts.
CN201510900967.XA 2015-12-09 2015-12-09 Traditional Chinese medicine composition for treating hyperplasia of mammary glands Pending CN105381142A (en)

Priority Applications (1)

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CN201510900967.XA CN105381142A (en) 2015-12-09 2015-12-09 Traditional Chinese medicine composition for treating hyperplasia of mammary glands

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104043049A (en) * 2014-06-25 2014-09-17 梁黎明 Traditional Chinese medicine composition for treating hyperplasia of mammary glands
CN105056146A (en) * 2015-08-31 2015-11-18 谢丽蓉 Chinese patent medicine for treating blood stasis accumulation type breast hyperplasia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104043049A (en) * 2014-06-25 2014-09-17 梁黎明 Traditional Chinese medicine composition for treating hyperplasia of mammary glands
CN105056146A (en) * 2015-08-31 2015-11-18 谢丽蓉 Chinese patent medicine for treating blood stasis accumulation type breast hyperplasia

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
马春瑜: "《经方验方治疗妇科常见病》", 31 May 2014, 甘肃科学技术出版社 *

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Application publication date: 20160309